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Conserved domains on  [gi|501454705|ref|WP_012478150|]
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MULTISPECIES: DeoR/GlpR family DNA-binding transcription regulator [Agrobacterium]

Protein Classification

DeoR/GlpR family DNA-binding transcription regulator( domain architecture ID 11442564)

DeoR/GlpR family DNA-binding transcription regulator is a helix-turn-helix type transcriptional regulator that may be involved in sugar metabolism

Gene Ontology:  GO:0003700|GO:0003677
PubMed:  15808743

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 5-253 2.62e-75

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


:

Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 229.25  E-value: 2.62e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705   5 TQDRQAKIVELLRGEQFLSIGKLTDHFEISVATARRDLSELHEAGLLRRTHGGAVSVSQVAQDKPNAARAVSHQAEKAVI 84
Cdd:COG1349    3 AEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSAAAEPPFAERETLNAEEKRAI 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705  85 AAAAAAMIKDGDAVLLDAGTTALEVAKHISGRAGLTLISNGADIVAELIRGETKNVYSVGGEYTETNRSFRGPLAEQFIR 164
Cdd:COG1349   83 ARAAASLIEDGDTIFLDAGTTTLALARALPDRRNLTVVTNSLNIANELAERPNIEVILLGGELRPSSGSLVGPLAEEALR 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705 165 QFNVDKLILNASSIDLDRGLiCTASPLNASVQKAMIEVASRVIVVADHSKFTKSSLSVTARIEDVGVIVTDAGArsiiet 244
Cdd:COG1349  163 RFRADKAFLGASGIDAEGGL-TTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGP------ 235


                 ....*....
gi 501454705 245 vPEKLRKKL 253
Cdd:COG1349  236 -PPELLEAL 243
 
Name Accession Description Interval E-value
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 5-253 2.62e-75

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 229.25  E-value: 2.62e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705   5 TQDRQAKIVELLRGEQFLSIGKLTDHFEISVATARRDLSELHEAGLLRRTHGGAVSVSQVAQDKPNAARAVSHQAEKAVI 84
Cdd:COG1349    3 AEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSAAAEPPFAERETLNAEEKRAI 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705  85 AAAAAAMIKDGDAVLLDAGTTALEVAKHISGRAGLTLISNGADIVAELIRGETKNVYSVGGEYTETNRSFRGPLAEQFIR 164
Cdd:COG1349   83 ARAAASLIEDGDTIFLDAGTTTLALARALPDRRNLTVVTNSLNIANELAERPNIEVILLGGELRPSSGSLVGPLAEEALR 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705 165 QFNVDKLILNASSIDLDRGLiCTASPLNASVQKAMIEVASRVIVVADHSKFTKSSLSVTARIEDVGVIVTDAGArsiiet 244
Cdd:COG1349  163 RFRADKAFLGASGIDAEGGL-TTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGP------ 235


                 ....*....
gi 501454705 245 vPEKLRKKL 253
Cdd:COG1349  236 -PPELLEAL 243
DeoRC pfam00455
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive ...
 91-236 3.55e-53

DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site. DeorC senses diverse sugar derivatives such as deoxyribose nucleoside (DeoR), tagatose phosphate (LacR), galactosamine (AgaR), myo-inositol (Bacillus IolR) and L-ascorbate (UlaR). It can also bind L-ascorbate 6-phosphate, agrocinopines, sn-glycerol 3-phosphate, and sulfoquinovose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 395365  Cd Length: 160  Bit Score: 169.61  E-value: 3.55e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705   91 MIKDGDAVLLDAGTTALEVAKHISGRAGLTLISNGADIVAELIRGETKNVYSVGGEYTETNRSFRGPLAEQFIRQFNVDK 170
Cdd:pfam00455  16 LIEDGDTIFLDAGTTTLELARALPDRRNLTVITNSLNIANELSEKPDIEVILLGGEVRPKTGAFVGPLAEEFLRQFNVDK 95

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 501454705  171 LILNASSIDLDRGLiCTASPLNASVQKAMIEVASRVIVVADHSKFTKSSLSVTARIEDVGVIVTDA 236
Cdd:pfam00455  96 AFIGANGIDLEGGL-TTSDEEEAEVKRAMIEAARRVILLADSSKFGKRAFARFAPLEDIDALITDK 160
TranRegGlpR_Halo NF041397
HTH-type transcriptional regulator GlpR;
8-257 1.28e-49

HTH-type transcriptional regulator GlpR;


Pssm-ID: 469288 [Multi-domain]  Cd Length: 253  Bit Score: 163.54  E-value: 1.28e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705   8 RQAKIVELLRGEQFLSIGKLTDHFEISVATARRDLSELHEAGLLRRTHGGAVSVSQVAQDKPNAARAVSHQAEKAVIAAA 87
Cdd:NF041397   6 RKRKIVELVTERDGCSVEELADELDVSKATIRRDLRDLEDRGLIERSHGGAVPVTSVGRERSYGQREVQNLEAKRAIAER 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705  88 AAAMIKDGDAVLLDAGTTALEVAKHISGRAGLTLISNGADIVAELIRGETkNVYSVGGEYTETNRSFRGPLAEQFIRQFN 167
Cdd:NF041397  86 AVEEIHDGQVVFFDAGTTTMEVAKRVPTDGSFLAVTNSPLLALELAERDG-EVKLTGGTLRPRTRALVGPTAESFMERTN 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705 168 VDKLILNASSIDLDRGLIcTASPLNASVQKAMIEVASRVIVVADHSKFTKSSLSVTARIEDVGVIVTDagarsiiETVPE 247
Cdd:NF041397 165 FDLLFLGTNGIDPDGGLT-TPNEDEARMKELMVENAKRVVLVADGSKFGERSFVRFADLDDVDLFVTD-------GALPE 236

                        250
                 ....*....|
gi 501454705 248 KLRKKLVIAN 257
Cdd:NF041397 237 ELREAFEEAG 246
srlR PRK10434
DNA-binding transcriptional repressor;
6-252 1.72e-44

DNA-binding transcriptional repressor;


Pssm-ID: 182457 [Multi-domain]  Cd Length: 256  Bit Score: 150.61  E-value: 1.72e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705   6 QDRQAKIVELLRGEQFLSIGKLTDHFEISVATARRDLSELHEAGLLRRTHGGAVsVSQVAQDKPNAARAVSHQAEKAVIA 85
Cdd:PRK10434   4 RQRQAAILEYLQKQGKTSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVV-LNKEESDPPIDHKTLINTHKKELIA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705  86 AAAAAMIKDGDAVLLDAGTTALEVAKHISGRAGLTLISNGADIVAELIrgETKNVYSV---GGEYTETNRSFRGPLAEQF 162
Cdd:PRK10434  83 EAAVSLIHDGDSIILDAGSTVLQMVPLLSRFNNITVMTNSLHIVNALS--ELDNEQTIlmpGGTFRKKSASFHGQLAENA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705 163 IRQFNVDKLILNASSIDLDRGLictaSPLNA--SVQKAMIEVASRVIVVADHSKFTKSSLSVTARIEDVGVIVTDAGars 240
Cdd:PRK10434 161 FEHFTFDKLFIGTDGIDLNAGV----TTFNEvyTVSKAMCNAAREIILMADSSKFGRKSPNVVCSLEKVDKLITDAG--- 233

                        250
                 ....*....|..
gi 501454705 241 IIETVPEKLRKK 252
Cdd:PRK10434 234 IDPAFRQALEEK 245
HTH_DEOR smart00420
helix_turn_helix, Deoxyribose operon repressor;
8-60 5.27e-16

helix_turn_helix, Deoxyribose operon repressor;


Pssm-ID: 197714 [Multi-domain]  Cd Length: 53  Bit Score: 69.94  E-value: 5.27e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 501454705     8 RQAKIVELLRGEQFLSIGKLTDHFEISVATARRDLSELHEAGLLRRTHGGAVS 60
Cdd:smart00420   1 RQQQILELLAQQGKVSVEELAELLGVSEMTIRRDLNKLEEQGLLTRVHGGAVS 53
 
Name Accession Description Interval E-value
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 5-253 2.62e-75

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 229.25  E-value: 2.62e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705   5 TQDRQAKIVELLRGEQFLSIGKLTDHFEISVATARRDLSELHEAGLLRRTHGGAVSVSQVAQDKPNAARAVSHQAEKAVI 84
Cdd:COG1349    3 AEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSAAAEPPFAERETLNAEEKRAI 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705  85 AAAAAAMIKDGDAVLLDAGTTALEVAKHISGRAGLTLISNGADIVAELIRGETKNVYSVGGEYTETNRSFRGPLAEQFIR 164
Cdd:COG1349   83 ARAAASLIEDGDTIFLDAGTTTLALARALPDRRNLTVVTNSLNIANELAERPNIEVILLGGELRPSSGSLVGPLAEEALR 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705 165 QFNVDKLILNASSIDLDRGLiCTASPLNASVQKAMIEVASRVIVVADHSKFTKSSLSVTARIEDVGVIVTDAGArsiiet 244
Cdd:COG1349  163 RFRADKAFLGASGIDAEGGL-TTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGP------ 235


                 ....*....
gi 501454705 245 vPEKLRKKL 253
Cdd:COG1349  236 -PPELLEAL 243
DeoRC pfam00455
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive ...
 91-236 3.55e-53

DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site. DeorC senses diverse sugar derivatives such as deoxyribose nucleoside (DeoR), tagatose phosphate (LacR), galactosamine (AgaR), myo-inositol (Bacillus IolR) and L-ascorbate (UlaR). It can also bind L-ascorbate 6-phosphate, agrocinopines, sn-glycerol 3-phosphate, and sulfoquinovose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 395365  Cd Length: 160  Bit Score: 169.61  E-value: 3.55e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705   91 MIKDGDAVLLDAGTTALEVAKHISGRAGLTLISNGADIVAELIRGETKNVYSVGGEYTETNRSFRGPLAEQFIRQFNVDK 170
Cdd:pfam00455  16 LIEDGDTIFLDAGTTTLELARALPDRRNLTVITNSLNIANELSEKPDIEVILLGGEVRPKTGAFVGPLAEEFLRQFNVDK 95

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 501454705  171 LILNASSIDLDRGLiCTASPLNASVQKAMIEVASRVIVVADHSKFTKSSLSVTARIEDVGVIVTDA 236
Cdd:pfam00455  96 AFIGANGIDLEGGL-TTSDEEEAEVKRAMIEAARRVILLADSSKFGKRAFARFAPLEDIDALITDK 160
TranRegGlpR_Halo NF041397
HTH-type transcriptional regulator GlpR;
8-257 1.28e-49

HTH-type transcriptional regulator GlpR;


Pssm-ID: 469288 [Multi-domain]  Cd Length: 253  Bit Score: 163.54  E-value: 1.28e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705   8 RQAKIVELLRGEQFLSIGKLTDHFEISVATARRDLSELHEAGLLRRTHGGAVSVSQVAQDKPNAARAVSHQAEKAVIAAA 87
Cdd:NF041397   6 RKRKIVELVTERDGCSVEELADELDVSKATIRRDLRDLEDRGLIERSHGGAVPVTSVGRERSYGQREVQNLEAKRAIAER 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705  88 AAAMIKDGDAVLLDAGTTALEVAKHISGRAGLTLISNGADIVAELIRGETkNVYSVGGEYTETNRSFRGPLAEQFIRQFN 167
Cdd:NF041397  86 AVEEIHDGQVVFFDAGTTTMEVAKRVPTDGSFLAVTNSPLLALELAERDG-EVKLTGGTLRPRTRALVGPTAESFMERTN 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705 168 VDKLILNASSIDLDRGLIcTASPLNASVQKAMIEVASRVIVVADHSKFTKSSLSVTARIEDVGVIVTDagarsiiETVPE 247
Cdd:NF041397 165 FDLLFLGTNGIDPDGGLT-TPNEDEARMKELMVENAKRVVLVADGSKFGERSFVRFADLDDVDLFVTD-------GALPE 236

                        250
                 ....*....|
gi 501454705 248 KLRKKLVIAN 257
Cdd:NF041397 237 ELREAFEEAG 246
srlR PRK10434
DNA-binding transcriptional repressor;
6-252 1.72e-44

DNA-binding transcriptional repressor;


Pssm-ID: 182457 [Multi-domain]  Cd Length: 256  Bit Score: 150.61  E-value: 1.72e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705   6 QDRQAKIVELLRGEQFLSIGKLTDHFEISVATARRDLSELHEAGLLRRTHGGAVsVSQVAQDKPNAARAVSHQAEKAVIA 85
Cdd:PRK10434   4 RQRQAAILEYLQKQGKTSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVV-LNKEESDPPIDHKTLINTHKKELIA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705  86 AAAAAMIKDGDAVLLDAGTTALEVAKHISGRAGLTLISNGADIVAELIrgETKNVYSV---GGEYTETNRSFRGPLAEQF 162
Cdd:PRK10434  83 EAAVSLIHDGDSIILDAGSTVLQMVPLLSRFNNITVMTNSLHIVNALS--ELDNEQTIlmpGGTFRKKSASFHGQLAENA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705 163 IRQFNVDKLILNASSIDLDRGLictaSPLNA--SVQKAMIEVASRVIVVADHSKFTKSSLSVTARIEDVGVIVTDAGars 240
Cdd:PRK10434 161 FEHFTFDKLFIGTDGIDLNAGV----TTFNEvyTVSKAMCNAAREIILMADSSKFGRKSPNVVCSLEKVDKLITDAG--- 233

                        250
                 ....*....|..
gi 501454705 241 IIETVPEKLRKK 252
Cdd:PRK10434 234 IDPAFRQALEEK 245
PRK09802 PRK09802
DeoR family transcriptional regulator;
5-237 1.58e-33

DeoR family transcriptional regulator;


Pssm-ID: 182086 [Multi-domain]  Cd Length: 269  Bit Score: 122.27  E-value: 1.58e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705   5 TQDRQAKIVELLRGEQFLSIGKLTDHFEISVATARRDLSELHEAGLLRRTHGGAV-------SVSQVAQDKPNAARAVSH 77
Cdd:PRK09802  15 TSERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGIAVRAYGGALicdsttpSVEPSVEDKSALNTAMKR 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705  78 QAEKAVIAaaaaaMIKDGDAVLLDAGTTALEVAKHISGRAGLTLISNGADIVAELIRGETKNVYSVGGEYTETNRSFRGP 157
Cdd:PRK09802  95 SVAKAAVE-----LIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLRRQSQSFYGD 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705 158 LAEQFIRQFNVDKLILNASSIDLDRGlICTASPLNASVQKAMIEVASRVIVVADHSKFTKSSLSVTARIEDVGVIVTDAG 237
Cdd:PRK09802 170 QAEQSLQNYHFDMLFLGVDAIDLERG-VSTHNEDEARLNRRMCEVAERIIVVTDSSKFNRSSLHKIIDTQRIDMIIVDEG 248
PRK10906 PRK10906
DeoR/GlpR family transcriptional regulator;
8-243 2.71e-24

DeoR/GlpR family transcriptional regulator;


Pssm-ID: 182827 [Multi-domain]  Cd Length: 252  Bit Score: 97.62  E-value: 2.71e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705   8 RQAKIVELLRGEQFLSIGKLTDHFEISVATARRDLSELHEAGLLRRTHGGAV----SVSQVAQDkpnaaRAVSHQAEKAV 83
Cdd:PRK10906   6 RHDAIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNDLAEQNKILRHHGGAAlpssSVNTPWHD-----RKATQTEEKER 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705  84 IAAAAAAMIKDGDAVLLDAGTTALEVAKHISGRAGLTLISNGADIVAELIRGETKNVYSVGGEYTETNRSFRGPLAEQFI 163
Cdd:PRK10906  81 IARKVASQIPNGATLFIDIGTTPEAVAHALLNHSNLRIVTNNLNVANTLMAKEDFRIILAGGELRSRDGGIIGEATLDFI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705 164 RQFNVDKLILNASSIDLDrGLICTASPLNASVQKAMIEVASRVIVVADHSKFTKSSLSVTARIEDVGVIVTD----AGAR 239
Cdd:PRK10906 161 SQFRLDFGILGISGIDSD-GSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVNMGSISMVDAVYTDqlppASVM 239


                 ....
gi 501454705 240 SIIE 243
Cdd:PRK10906 240 QVIE 243
PRK10411 PRK10411
L-fucose operon activator;
8-236 1.88e-19

L-fucose operon activator;


Pssm-ID: 236684 [Multi-domain]  Cd Length: 240  Bit Score: 84.47  E-value: 1.88e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705   8 RQAKIVELLRGEQFLSIGKLTDHFEISVATARRDLSELHEAGLLRRTHGGAVSVSQVAQD--KPNAARAVSHQAEKAVIA 85
Cdd:PRK10411   5 RQQAIVDLLLNHTSLTTEALAEQLNVSKETIRRDLNELQTQGKILRNHGRAKYIHRQNQDsgDPFHIRLKSHYAHKADIA 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705  86 AAAAAMIKDGDAVLLDAGTTALEVAKHISGRAgLTLISNGADIVAELIRGETKNVYSVGGEYTETNRSFRGPLAEQFIRQ 165
Cdd:PRK10411  85 REALAWIEEGMVIALDASSTCWYLARQLPDIN-IQVFTNSHPICQELGKRERIQLISSGGTLERKYGCYVNPSLISQLKS 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 501454705 166 FNVDKLILNASSIDlDRGLICTASPLNASVQKAMIEVASRVIVVADHSKFTKSSLSVTARIEDVGVIVTDA 236
Cdd:PRK10411 164 LEIDLFIFSCEGID-SSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDE 233
HTH_DeoR pfam08220
DeoR-like helix-turn-helix domain;
8-64 1.36e-17

DeoR-like helix-turn-helix domain;


Pssm-ID: 285436 [Multi-domain]  Cd Length: 57  Bit Score: 74.22  E-value: 1.36e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 501454705    8 RQAKIVELLRGEQFLSIGKLTDHFEISVATARRDLSELHEAGLLRRTHGGAVSVSQV 64
Cdd:pfam08220   1 RIQQILELLKQQGTLSVEELAELLGVSEMTIRRDLNELEEQGLLTRTHGGAVSNSST 57
PRK13509 PRK13509
HTH-type transcriptional regulator UlaR;
8-238 2.20e-17

HTH-type transcriptional regulator UlaR;


Pssm-ID: 184100 [Multi-domain]  Cd Length: 251  Bit Score: 78.89  E-value: 2.20e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705   8 RQAKIVELLRGEQFLSIGKLTDHFEISVATARRDLSELHEAGLLRRTHGGAVSVSqvaQDKPNAARAVSHQAEKAVI--- 84
Cdd:PRK13509   6 RHQILLELLAQLGFVTVEKVIERLGISPATARRDINKLDESGKLKKVRNGAEAIT---QQRPRWTPMNIHQAQNHDEkvr 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705  85 -AAAAAAMIKDGDAVLLDAGTTALEVAKHISGRaGLTLISNGADIVAELIRGETKNVYSVGGEYTETNRSFRGPlaeqfi 163
Cdd:PRK13509  83 iAKAASQLCNPGESVVINCGSTAFLLGRELCGK-PVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSP------ 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705 164 rqfNVDKLILNASSIDLDRGLICTASPL------NASVQKAMIEVASRVIVVADHSKFTKSSLSVTARIEDVGVIVTDAG 237
Cdd:PRK13509 156 ---QGSENSLYAGHWMFTSGKGLTADGLyktdmlTAMAEQKMLSVVGKLVVLVDSSKIGERAGMLFSRADQIDMLITGKN 232


                 .
gi 501454705 238 A 238
Cdd:PRK13509 233 A 233
HTH_DEOR smart00420
helix_turn_helix, Deoxyribose operon repressor;
8-60 5.27e-16

helix_turn_helix, Deoxyribose operon repressor;


Pssm-ID: 197714 [Multi-domain]  Cd Length: 53  Bit Score: 69.94  E-value: 5.27e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 501454705     8 RQAKIVELLRGEQFLSIGKLTDHFEISVATARRDLSELHEAGLLRRTHGGAVS 60
Cdd:smart00420   1 RQQQILELLAQQGKVSVEELAELLGVSEMTIRRDLNKLEEQGLLTRVHGGAVS 53
COG3177 COG3177
Fic family protein [Transcription];
7-57 1.03e-06

Fic family protein [Transcription];


Pssm-ID: 442410 [Multi-domain]  Cd Length: 316  Bit Score: 48.91  E-value: 1.03e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 501454705   7 DRQAKIVELLRGEQFLSIGKLTDHFEISVATARRDLSELHEAGLLRRTHGG 57
Cdd:COG3177  261 ERQRKLLELLFENPVLTASELAELLGVSRRTARRDLKDLVELGILEKVGGG 311
YobV COG2378
Predicted DNA-binding transcriptional regulator YobV, contains HTH and WYL domains ...
 7-49 2.17e-05

Predicted DNA-binding transcriptional regulator YobV, contains HTH and WYL domains [Transcription];


Pssm-ID: 441945 [Multi-domain]  Cd Length: 314  Bit Score: 44.68  E-value: 2.17e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 501454705   7 DRQAKIVELLRGEQFLSIGKLTDHFEISVATARRDLSELHEAG 49
Cdd:COG2378    5 ERLLALLQLLQSRRGVTAAELAERLEVSERTIYRDIDALRELG 47
COG2345 COG2345
Predicted transcriptional regulator, ArsR family [Transcription];
4-54 7.89e-04

Predicted transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 441914 [Multi-domain]  Cd Length: 217  Bit Score: 39.52  E-value: 7.89e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 501454705   4 STQDRqakIVELLRGEQFLSIGKLTDHFEISVATARRDLSELHEAGLLRRT 54
Cdd:COG2345   13 PTRRR---ILELLKRAGPVTAAELAEALGLTPNAVRRHLDALEEEGLVERE 60
PRK10681 PRK10681
DNA-binding transcriptional repressor DeoR; Provisional
 144-235 1.25e-03

DNA-binding transcriptional repressor DeoR; Provisional


Pssm-ID: 182644 [Multi-domain]  Cd Length: 252  Bit Score: 39.29  E-value: 1.25e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501454705 144 GGEYTETNRSFRgPLAEQ-FIRQFNVDKLILNASSIDLDRGLICTASPLNASVQKAMiEVASRVIVVADHSKFTKSSlsv 222
Cdd:PRK10681 142 GGEFHASNAIFK-PLDFQqTLDNICPDIAFYSAAGVHVSKGATCFNLEELPVKHWAM-AMAQKHVLVVDHSKFGKVR--- 216

                         90
                 ....*....|....*.
gi 501454705 223 TARIEDVG---VIVTD 235
Cdd:PRK10681 217 PARMGDLTrfdTVVSD 232
HTH_11 pfam08279
HTH domain; This family includes helix-turn-helix domains in a wide variety of proteins.
 11-50 1.32e-03

HTH domain; This family includes helix-turn-helix domains in a wide variety of proteins.


Pssm-ID: 429896 [Multi-domain]  Cd Length: 52  Bit Score: 35.87  E-value: 1.32e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 501454705   11 KIVELLR-GEQFLSIGKLTDHFEISVATARRDLSELHEAGL 50
Cdd:pfam08279   2 QILQLLLeARGPISGQELAEKLGVSRRTIRRDIKILEELGV 42
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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