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Conserved domains on  [gi|501404921|ref|WP_012436487|]
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MULTISPECIES: 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase PaaG [Ralstonia]

Protein Classification

enoyl-CoA hydratase( domain architecture ID 10793017)

enoyl-CoA hydratase such as 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase, which catalyzes the reversible conversion of the epoxide to 2-oxepin-2(3H)-ylideneacetyl-CoA (oxepin-CoA)

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
1-262 2.45e-148

enoyl-CoA hydratase; Provisional


:

Pssm-ID: 236163  Cd Length: 262  Bit Score: 414.70  E-value: 2.45e-148
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQRARALILTGAGRGFCAGQDLSELNFTP-GQMTDL 79
Cdd:PRK08140   1 MMYETILLAIEAGVATLTLNRPDKLNSFTREMHRELREALDQVEDDGARALLLTGAGRGFCAGQDLADRDVTPgGAMPDL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  80 GQLIDEQFNPLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARS 159
Cdd:PRK08140  81 GESIETFYNPLVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGMARA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 160 MGLAMLGEKLDAKTALAWGLIWGVYHDAKiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRELG 239
Cdd:PRK08140 161 LGLALLGEKLSAEQAEQWGLIWRVVDDAA-LADEAQQLAAHLATQPTRGLALIKQAMNASATNTLDAQLDLERDLQREAG 239
                        250       260
                 ....*....|....*....|...
gi 501404921 240 NSRDYAEGVDAFLNKRVAHFTGE 262
Cdd:PRK08140 240 RSADYAEGVSAFLEKRAPRFTGR 262
 
Name Accession Description Interval E-value
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
1-262 2.45e-148

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 414.70  E-value: 2.45e-148
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQRARALILTGAGRGFCAGQDLSELNFTP-GQMTDL 79
Cdd:PRK08140   1 MMYETILLAIEAGVATLTLNRPDKLNSFTREMHRELREALDQVEDDGARALLLTGAGRGFCAGQDLADRDVTPgGAMPDL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  80 GQLIDEQFNPLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARS 159
Cdd:PRK08140  81 GESIETFYNPLVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGMARA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 160 MGLAMLGEKLDAKTALAWGLIWGVYHDAKiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRELG 239
Cdd:PRK08140 161 LGLALLGEKLSAEQAEQWGLIWRVVDDAA-LADEAQQLAAHLATQPTRGLALIKQAMNASATNTLDAQLDLERDLQREAG 239
                        250       260
                 ....*....|....*....|...
gi 501404921 240 NSRDYAEGVDAFLNKRVAHFTGE 262
Cdd:PRK08140 240 RSADYAEGVSAFLEKRAPRFTGR 262
PaaB1 TIGR02280
phenylacetate degradation probable enoyl-CoA hydratase paaB; This family of proteins are found ...
6-262 1.86e-145

phenylacetate degradation probable enoyl-CoA hydratase paaB; This family of proteins are found within apparent operons for the degradation of phenylacetic acid. These proteins contain the enoyl-CoA hydratase domain as detected by pfam00378. This activity is consistent with current hypotheses for the degradation pathway, which involve the ligation of phenylacetate with coenzyme A (paaF), hydroxylation (paaGHIJK), ring-opening (paaN) and degradation of the resulting fatty acid-like compound to a Krebs cycle intermediate (paaABCDE).


Pssm-ID: 274065  Cd Length: 257  Bit Score: 407.32  E-value: 1.86e-145
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921    6 ILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQR-ARALILTGAGRGFCAGQDLSELNFTPGQMTDLGQLID 84
Cdd:TIGR02280   1 ILSHLEKGVATLTLNRPDKLNSFNAEMHAELAEALKRVERDDtARALLLTGAGRGFCAGQDLSDRNVTPGPAPDLGMTVE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   85 EQFNPLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARSMGLAM 164
Cdd:TIGR02280  81 RFYNPLVRRLAALPKPVICAVNGVAAGAGANLALAGDIVIAARSAKFIQAFSKLGLIPDSGGTWLLPRLVGRARAMGLAL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  165 LGEKLDAKTALAWGLIWGVYHDAkILMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRELGNSRDY 244
Cdd:TIGR02280 161 LGNKLSAEQAHEWGLIWQVVDDA-TLMDEAQALARHLATQPTRGLGLIKRAIQAAETNSLDTQLDLERDLQREAGRSADY 239
                         250
                  ....*....|....*...
gi 501404921  245 AEGVDAFLNKRVAHFTGE 262
Cdd:TIGR02280 240 AEGVSAFLDKRSPQFTGK 257
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
6-255 1.45e-72

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 222.35  E-value: 1.45e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   6 ILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAGRGFCAGQDLSElnFTPGQMTDLGQLID 84
Cdd:COG1024    1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDvRVVVLTGAGKAFCAGADLKE--LAAAADPEEARAFA 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  85 EQFNPLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARSMGLAM 164
Cdd:COG1024   79 RGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLL 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 165 LGEKLDAKTALAWGLIWGVYHDAKiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRELGNSRDY 244
Cdd:COG1024  159 TGRRIDAEEALELGLVNRVVPDDE-LLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDA 237
                        250
                 ....*....|.
gi 501404921 245 AEGVDAFLNKR 255
Cdd:COG1024  238 REGIAAFLEKR 248
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
14-261 1.72e-53

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 173.70  E-value: 1.72e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   14 VATITLNRPDQLNSFTAGMHRELREALDKVER-QRARALILTGAGRGFCAGQDLSEL-NFTPGQMTDLGqlidEQFNPLV 91
Cdd:pfam00378   6 VAVITLNRPEAVNALSAELITELIQALEKLRTdPSVRAVVLTGGDKAFCAGADLKEMyGEGPAHQALYR----ENVLDLW 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   92 RRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARSMGLAMLGEKLDA 171
Cdd:pfam00378  82 TLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISA 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  172 KTALAWGLIWGVYHDAKILMTEVNCMAdHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRELGNSRDYAEGVDAF 251
Cdd:pfam00378 162 QEALKWGLVDKVVPEDQLLDEARELAE-KLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQAF 240
                         250
                  ....*....|
gi 501404921  252 LNKRVAHFTG 261
Cdd:pfam00378 241 LEKRKPPWED 250
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
6-190 6.85e-47

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 154.64  E-value: 6.85e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   6 ILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQR-ARALILTGAGRGFCAGQDLSELNFTPGQMTDLGQLID 84
Cdd:cd06558    1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPdVRVVVLTGAGKAFCAGADLKELAALSDAGEEARAFIR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  85 EqFNPLVRRLRAMPLPVIaavngvaagaganlalACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARSMGLAM 164
Cdd:cd06558   81 E-LQELLRALLRLPKPVIaavngaalggglelalACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLL 159
                        170       180
                 ....*....|....*....|....*.
gi 501404921 165 LGEKLDAKTALAWGLIWGVYHDAKIL 190
Cdd:cd06558  160 TGRRISAEEALELGLVDEVVPDEELL 185
 
Name Accession Description Interval E-value
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
1-262 2.45e-148

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 414.70  E-value: 2.45e-148
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQRARALILTGAGRGFCAGQDLSELNFTP-GQMTDL 79
Cdd:PRK08140   1 MMYETILLAIEAGVATLTLNRPDKLNSFTREMHRELREALDQVEDDGARALLLTGAGRGFCAGQDLADRDVTPgGAMPDL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  80 GQLIDEQFNPLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARS 159
Cdd:PRK08140  81 GESIETFYNPLVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGMARA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 160 MGLAMLGEKLDAKTALAWGLIWGVYHDAKiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRELG 239
Cdd:PRK08140 161 LGLALLGEKLSAEQAEQWGLIWRVVDDAA-LADEAQQLAAHLATQPTRGLALIKQAMNASATNTLDAQLDLERDLQREAG 239
                        250       260
                 ....*....|....*....|...
gi 501404921 240 NSRDYAEGVDAFLNKRVAHFTGE 262
Cdd:PRK08140 240 RSADYAEGVSAFLEKRAPRFTGR 262
PaaB1 TIGR02280
phenylacetate degradation probable enoyl-CoA hydratase paaB; This family of proteins are found ...
6-262 1.86e-145

phenylacetate degradation probable enoyl-CoA hydratase paaB; This family of proteins are found within apparent operons for the degradation of phenylacetic acid. These proteins contain the enoyl-CoA hydratase domain as detected by pfam00378. This activity is consistent with current hypotheses for the degradation pathway, which involve the ligation of phenylacetate with coenzyme A (paaF), hydroxylation (paaGHIJK), ring-opening (paaN) and degradation of the resulting fatty acid-like compound to a Krebs cycle intermediate (paaABCDE).


Pssm-ID: 274065  Cd Length: 257  Bit Score: 407.32  E-value: 1.86e-145
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921    6 ILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQR-ARALILTGAGRGFCAGQDLSELNFTPGQMTDLGQLID 84
Cdd:TIGR02280   1 ILSHLEKGVATLTLNRPDKLNSFNAEMHAELAEALKRVERDDtARALLLTGAGRGFCAGQDLSDRNVTPGPAPDLGMTVE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   85 EQFNPLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARSMGLAM 164
Cdd:TIGR02280  81 RFYNPLVRRLAALPKPVICAVNGVAAGAGANLALAGDIVIAARSAKFIQAFSKLGLIPDSGGTWLLPRLVGRARAMGLAL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  165 LGEKLDAKTALAWGLIWGVYHDAkILMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRELGNSRDY 244
Cdd:TIGR02280 161 LGNKLSAEQAHEWGLIWQVVDDA-TLMDEAQALARHLATQPTRGLGLIKRAIQAAETNSLDTQLDLERDLQREAGRSADY 239
                         250
                  ....*....|....*...
gi 501404921  245 AEGVDAFLNKRVAHFTGE 262
Cdd:TIGR02280 240 AEGVSAFLDKRSPQFTGK 257
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
1-261 9.15e-74

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 225.77  E-value: 9.15e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVE--RQRARALILTGAGRGFCAGQDLSELNFTPGQM-- 76
Cdd:PRK05981   1 MQFKKVTLDFDGGVAILTLDHPEVMNAVSIDMLGGLAEALDAIEdgKAEVRCLVLTGAGRGFCTGANLQGRGSGGRESds 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  77 -TDLGQLIDEQFNPLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIG 155
Cdd:PRK05981  81 gGDAGAALETAYHPFLRRLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 156 VARSMGLAMLGEKLDAKTALAWGLIWGVYHDAKiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQ 235
Cdd:PRK05981 161 KARAMELSLLGEKLPAETALQWGLVNRVVDDAE-LMAEAMKLAHELANGPTVALGLIRKLYWDSPENDFEEQLNLEREAQ 239
                        250       260
                 ....*....|....*....|....*.
gi 501404921 236 RELGNSRDYAEGVDAFLNKRVAHFTG 261
Cdd:PRK05981 240 RIAGKTEDFKEGVGAFLQKRPAQFKG 265
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
6-255 1.45e-72

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 222.35  E-value: 1.45e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   6 ILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAGRGFCAGQDLSElnFTPGQMTDLGQLID 84
Cdd:COG1024    1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDvRVVVLTGAGKAFCAGADLKE--LAAAADPEEARAFA 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  85 EQFNPLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARSMGLAM 164
Cdd:COG1024   79 RGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLL 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 165 LGEKLDAKTALAWGLIWGVYHDAKiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRELGNSRDY 244
Cdd:COG1024  159 TGRRIDAEEALELGLVNRVVPDDE-LLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDA 237
                        250
                 ....*....|.
gi 501404921 245 AEGVDAFLNKR 255
Cdd:COG1024  238 REGIAAFLEKR 248
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
1-261 1.17e-66

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 207.41  E-value: 1.17e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAGRGFCAGQDLSELNFTPGQMTDl 79
Cdd:PRK06688   2 TMVTDLLVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAvRVVVLTGAGRAFSAGGDIKDFPKAPPKPPD- 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  80 gqlIDEQFNPLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARS 159
Cdd:PRK06688  81 ---ELAPVNRFLRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIGRARA 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 160 MGLAMLGEKLDAKTALAWGLIWGVYHDAKiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRELG 239
Cdd:PRK06688 158 AEMLLLGEPLSAEEALRIGLVNRVVPAAE-LDAEADAQAAKLAAGPASALRYTKRAINAATLTELEEALAREAAGFGRLL 236
                        250       260
                 ....*....|....*....|..
gi 501404921 240 NSRDYAEGVDAFLNKRVAHFTG 261
Cdd:PRK06688 237 RTPDFREGATAFIEKRKPDFTG 258
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
14-261 1.72e-53

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 173.70  E-value: 1.72e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   14 VATITLNRPDQLNSFTAGMHRELREALDKVER-QRARALILTGAGRGFCAGQDLSEL-NFTPGQMTDLGqlidEQFNPLV 91
Cdd:pfam00378   6 VAVITLNRPEAVNALSAELITELIQALEKLRTdPSVRAVVLTGGDKAFCAGADLKEMyGEGPAHQALYR----ENVLDLW 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   92 RRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARSMGLAMLGEKLDA 171
Cdd:pfam00378  82 TLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISA 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  172 KTALAWGLIWGVYHDAKILMTEVNCMAdHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRELGNSRDYAEGVDAF 251
Cdd:pfam00378 162 QEALKWGLVDKVVPEDQLLDEARELAE-KLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQAF 240
                         250
                  ....*....|
gi 501404921  252 LNKRVAHFTG 261
Cdd:pfam00378 241 LEKRKPPWED 250
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
1-261 1.50e-48

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 161.41  E-value: 1.50e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDWH-EHVATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAGRGFCAGQDLSELNFTPG---- 74
Cdd:PRK06210   2 MAYDAVLYEVAdSGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAvRVIVLTGAGRGFCAGADMGELQTIDPsdgr 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  75 QMTDLGQLIDEQFNPLVRR---LRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLP 151
Cdd:PRK06210  82 RDTDVRPFVGNRRPDYQTRyhfLTALRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWILP 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 152 QRIGVARSMGLAMLGEKLDAKTALAWGLIWGVYHDAKiLMTEVNCMADHLAKQPT-RALAAIKRAMHAAPTQSL-DAQLD 229
Cdd:PRK06210 162 RLVGHANALDLLLSARTFYAEEALRLGLVNRVVPPDE-LMERTLAYAEDLARNVSpASMAVIKRQLYEDAFQTLaEATAR 240
                        250       260       270
                 ....*....|....*....|....*....|..
gi 501404921 230 LERDLQRELGnSRDYAEGVDAFLNKRVAHFTG 261
Cdd:PRK06210 241 ANREMHESLQ-RPDFIEGVASFLEKRPPRFPG 271
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
6-190 6.85e-47

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 154.64  E-value: 6.85e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   6 ILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQR-ARALILTGAGRGFCAGQDLSELNFTPGQMTDLGQLID 84
Cdd:cd06558    1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPdVRVVVLTGAGKAFCAGADLKELAALSDAGEEARAFIR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  85 EqFNPLVRRLRAMPLPVIaavngvaagaganlalACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARSMGLAM 164
Cdd:cd06558   81 E-LQELLRALLRLPKPVIaavngaalggglelalACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLL 159
                        170       180
                 ....*....|....*....|....*.
gi 501404921 165 LGEKLDAKTALAWGLIWGVYHDAKIL 190
Cdd:cd06558  160 TGRRISAEEALELGLVDEVVPDEELL 185
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
1-262 1.76e-45

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 153.59  E-value: 1.76e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPtILLDWHEHVATITLNRPDQLNSFTA-GMHRELREALDKVERQRA-RALILTGAGRGFCAGQDLSELNFTPGQMTD 78
Cdd:PRK09245   1 MTDF-LLVERDGHIVTLTMNRPETRNALSDnDAVDALVAACAAINADRSvRAVILTGAGTAFSSGGNVKDMRARVGAFGG 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  79 LGQLIDEQFNP----LVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRI 154
Cdd:PRK09245  80 SPADIRQGYRHgiqrIPLALYNLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRII 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 155 GVARSMGLAMLGEKLDAKTALAWGLIWGVYHDAKiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDL 234
Cdd:PRK09245 160 GMARAAEMAFTGDAIDAATALEWGLVSRVVPADQ-LLPAARALAERIAANPPHALRLTKRLLREGQHASLDTLLELSAAY 238
                        250       260
                 ....*....|....*....|....*...
gi 501404921 235 QRELGNSRDYAEGVDAFLNKRVAHFTGE 262
Cdd:PRK09245 239 QALAHHTADHREAVDAFLEKRPPVFTGR 266
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
1-261 1.48e-44

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 152.08  E-value: 1.48e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAGRGFCAGQDLS------ELNFTP 73
Cdd:PRK08260   1 MTYETIRYDVADGIATITLNRPDKLNAFTVTMARELIEAFDAADADDAvRAVIVTGAGRAFCAGADLSaggntfDLDAPR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  74 GQMTDLGQLIDEQFNPLVR--------RLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSG 145
Cdd:PRK08260  81 TPVEADEEDRADPSDDGVRdgggrvtlRIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 146 GTWFLPQRIGVARSMGLAMLGEKLDAKTALAWGLIWGVyHDAKILMTEVNCMADHLAKQPTRALAAIKRAM---HAAPTQ 222
Cdd:PRK08260 161 SSWFLPRLVGLQTALEWVYSGRVFDAQEALDGGLVRSV-HPPDELLPAARALAREIADNTSPVSVALTRQMmwrMAGADH 239
                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 501404921 223 SLDAQLDLERDLQrELGNSRDYAEGVDAFLNKRVAHFTG 261
Cdd:PRK08260 240 PMEAHRVDSRAIY-SRGRSGDGKEGVSSFLEKRPAVFPG 277
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
2-261 1.71e-43

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 148.22  E-value: 1.71e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   2 TSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAGRGFCAGQDLSEL----NFTPGQM 76
Cdd:PRK07511   1 MSAELLSRREGSTLVLTLSNPGARNALHPDMYAAGIEALNTAERDPSiRAVVLTGAGGFFCAGGNLNRLlenrAKPPSVQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  77 TDLgqliDEQFNPLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGV 156
Cdd:PRK07511  81 AAS----IDGLHDWIRAIRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARALPR 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 157 ARSMGLAMLGEKLDAKTALAWGLIWGVYHDAKILmTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQR 236
Cdd:PRK07511 157 QLATELLLEGKPISAERLHALGVVNRLAEPGQAL-AEALALADQLAAGSPNALARIKSLIADAPEATLAAQLEAERDHFV 235
                        250       260
                 ....*....|....*....|....*
gi 501404921 237 ELGNSRDYAEGVDAFLNKRVAHFTG 261
Cdd:PRK07511 236 ASLHHADALEGIAAFLEKRAPDYKR 260
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
5-262 4.01e-42

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 144.41  E-value: 4.01e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   5 TILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQRARALILTGAGRGFCAGQD----LSELNftPGQMTDLG 80
Cdd:PRK07659   7 SVVVKYEGRVATIMLNRPEALNALDEPMLKELLQALKEVAESSAHIVVLRGNGRGFSAGGDikmmLSSND--ESKFDGVM 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  81 QLIDEqfnpLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARSM 160
Cdd:PRK07659  85 NTISE----IVVTLYTMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKRVGENKAK 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 161 GLAMLGEKLDAKTALAWGLIWGVYHDAKILMTEvNCMADHLAKqPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRELGN 240
Cdd:PRK07659 161 QIIWEGKKLSATEALDLGLIDEVIGGDFQTAAK-QKISEWLQK-PLKAMIETKQIYCELNRSQLEQVLQLEKRAQYAMRQ 238
                        250       260
                 ....*....|....*....|..
gi 501404921 241 SRDYAEGVDAFLNKRVAHFTGE 262
Cdd:PRK07659 239 TADHKEGIRAFLEKRLPVFKGE 260
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
5-255 2.47e-40

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 139.87  E-value: 2.47e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   5 TILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAGRGFCAGQDLSELNfTPGQMTDLGQL- 82
Cdd:PRK07260   3 HIIYEVEDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSvRFLLINANGKVFSVGGDLVEMK-RAVDEDDVQSLv 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  83 -IDEQFNPLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARSMG 161
Cdd:PRK07260  82 kIAELVNEISFAIKQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTRAIGLNRATH 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 162 LAMLGEKLDAKTALAWGLIWGVYHDAKiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRELGNS 241
Cdd:PRK07260 162 LAMTGEALTAEKALEYGFVYRVAESEK-LEKTCEQLLKKLRRGSSNSYAAIKSLVWESFFKGWEDYAKLELALQESLAFK 240
                        250
                 ....*....|....
gi 501404921 242 RDYAEGVDAFLNKR 255
Cdd:PRK07260 241 EDFKEGVRAFSERR 254
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
6-262 3.17e-40

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 139.53  E-value: 3.17e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   6 ILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQ-RARALILTGAGRGFCAGQDLSELNftpgqmTDLGQLID 84
Cdd:PRK06072   2 IKVESREGYAIVTMSRPDKLNALNLEMRNEFISKLKQINADpKIRVVIVTGEGRAFCVGADLSEFA------PDFAIDLR 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  85 EQFNPLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLpQRIGVARSMGLAM 164
Cdd:PRK06072  76 ETFYPIIREIRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFL-LKLTGQRFYEILV 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 165 LGEKLDAKTALAWGLIwgvyhdaKIL---MTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRELGNS 241
Cdd:PRK06072 155 LGGEFTAEEAERWGLL-------KISedpLSDAEEMANRISNGPFQSYIAAKRMINLVLYNDLEEFLEYESAIQGYLGKT 227
                        250       260
                 ....*....|....*....|.
gi 501404921 242 RDYAEGVDAFLNKRVAHFTGE 262
Cdd:PRK06072 228 EDFKEGISSFKEKREPKFKGI 248
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
2-251 3.72e-36

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 128.69  E-value: 3.72e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   2 TSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVER-QRARALILTGAGRGFCAGQDLSELNFTPGQMT--D 78
Cdd:PRK05870   1 MMDPVLLDVDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEAdPDVHALVVTGAGKAFCAGADLTALGAAPGRPAedG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  79 LGQLIDEqfnplVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVAR 158
Cdd:PRK05870  81 LRRIYDG-----FLAVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGPQV 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 159 SMGLAMLGEKLDAKTALAWGLIWGVYHDakiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQ-SLDAQLDLERDLQRE 237
Cdd:PRK05870 156 ARAALLFGMRFDAEAAVRHGLALMVADD---PVAAALELAAGPAAAPRELVLATKASMRATASLaQHAAAVEFELGPQAA 232
                        250
                 ....*....|....
gi 501404921 238 LGNSRDYAEGVDAF 251
Cdd:PRK05870 233 SVQSPEFAARLAAA 246
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
1-262 1.23e-35

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 127.86  E-value: 1.23e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDWHEH-VATITLNRPDQLNSFTAGMHRELREALDK-VERQRARALILTGAGRGFCAGQDLSEL-NFTPGQMt 77
Cdd:PRK08138   4 TATDVVLLERPADgVALLRLNRPEARNALNMEVRQQLAEHFTElSEDPDIRAIVLTGGEKVFAAGADIKEFaTAGAIEM- 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  78 dLGQLIDEQFNPLVRrlraMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVA 157
Cdd:PRK08138  83 -YLRHTERYWEAIAQ----CPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVGKF 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 158 RSMGLAMLGEKLDAKTALAWGLIWGVYHDAKILMTEVNcMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRE 237
Cdd:PRK08138 158 KAMRMALTGCMVPAPEALAIGLVSEVVEDEQTLPRALE-LAREIARMPPLALAQIKEVVLAGADAPLDAALALERKAFQL 236
                        250       260
                 ....*....|....*....|....*
gi 501404921 238 LGNSRDYAEGVDAFLNKRVAHFTGE 262
Cdd:PRK08138 237 LFDSEDQKEGMDAFLEKRKPAYKGK 261
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
1-250 1.95e-35

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 127.01  E-value: 1.95e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAGRGFCAGQDLSELNFTPGQMTDL 79
Cdd:PRK06190   1 MTEPILLVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDvDVVVLTGADPAFCAGLDLKELGGDGSAYGAQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  80 GQLIDeqfnpLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARS 159
Cdd:PRK06190  81 DALPN-----PSPAWPAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGIGRA 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 160 MGLAMLGEKLDAKTALAWGLIWGVYHDAKILMTEVNcMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRElG 239
Cdd:PRK06190 156 RRMSLTGDFLDAADALRAGLVTEVVPHDELLPRARR-LAASIAGNNPAAVRALKASYDDGAAAQTGDALALEAEAARA-H 233
                        250
                 ....*....|.
gi 501404921 240 NSRDYAEGVDA 250
Cdd:PRK06190 234 NRSVSPDGIAA 244
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
14-261 2.70e-32

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 119.30  E-value: 2.70e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  14 VATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAGRGFCAGQDLSE-------------LNFTpgQMTdl 79
Cdd:PRK08258  27 VATITLNRPERKNPLTFESYAELRDLFRELVYADDvKAVVLTGAGGNFCSGGDVHEiigpltkmdmpelLAFT--RMT-- 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  80 GQLideqfnplVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLL-PDSGGTWFLPQRIGVAR 158
Cdd:PRK08258 103 GDL--------VKAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRVGLAgADMGACALLPRIIGQGR 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 159 SMGLAMLGEKLDAKTALAWGLIWGVyHDAKILMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQREL 238
Cdd:PRK08258 175 ASELLYTGRSMSAEEGERWGFFNRL-VEPEELLAEAQALARRLAAGPTFAHGMTKTMLHQEWDMGLEEAIEAEAQAQAIC 253
                        250       260
                 ....*....|....*....|...
gi 501404921 239 GNSRDYAEGVDAFLNKRVAHFTG 261
Cdd:PRK08258 254 MQTEDFRRAYEAFVAKRKPVFEG 276
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
12-262 1.05e-30

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 114.73  E-value: 1.05e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  12 EHVATITLNRPDQlNSFTAGMHRELREALDKVE-RQRARALILTGAGRGFCAGQDLSElnFTP-------GQMTDLGQLI 83
Cdd:PRK07658  10 DHVAVITLNHPPA-NALSSQVLHELSELLDQVEkDDNVRVVVIHGEGRFFSAGADIKE--FTSvteaeqaTELAQLGQVT 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  84 DEqfnplvrRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARSMGLA 163
Cdd:PRK07658  87 FE-------RVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALEMM 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 164 MLGEKLDAKTALAWGLIWGVYHDAKiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRELGNSRD 243
Cdd:PRK07658 160 LTSEPITGAEALKWGLVNGVFPEET-LLDDAKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKREAKIFGEVFTSED 238
                        250
                 ....*....|....*....
gi 501404921 244 YAEGVDAFLNKRVAHFTGE 262
Cdd:PRK07658 239 AKEGVQAFLEKRKPSFSGK 257
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
11-261 2.08e-30

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 114.09  E-value: 2.08e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  11 HEHVATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAGRGFCAGQDLSELnftpgQMTDLGQLIDEQFNP 89
Cdd:PRK09674   9 QQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSiGVCVITGNARFFAAGADLNEM-----AEKDLAATLNDPRPQ 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  90 LVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARSMGLAMLGEKL 169
Cdd:PRK09674  84 LWQRLQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASQMVLTGESI 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 170 DAKTALAWGLIWGVYHDAkILMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRELGNSRDYAEGVD 249
Cdd:PRK09674 164 TAQQAQQAGLVSEVFPPE-LTLERALQLASKIARHSPLALRAAKQALRQSQEVDLQAGLAQERQLFTLLAATEDRHEGIS 242
                        250
                 ....*....|..
gi 501404921 250 AFLNKRVAHFTG 261
Cdd:PRK09674 243 AFLEKRTPDFKG 254
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
1-259 1.65e-29

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 111.76  E-value: 1.65e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQR-ARALILTGAG-RGFCAGQDLSEL-NFTPGQMT 77
Cdd:PRK05809   1 MELKNVILEKEGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDnVYAVILTGAGeKAFVAGADISEMkDLNEEEGR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  78 DLGQLIDEQFnplvRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVA 157
Cdd:PRK05809  81 KFGLLGNKVF----RKLENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGPG 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 158 RSMGLAMLGEKLDAKTALAWGLIWGVYHDAKiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRE 237
Cdd:PRK05809 157 KAKELIYTGDMINAEEALRIGLVNKVVEPEK-LMEEAKALANKIAANAPIAVKLCKDAINRGMQVDIDTAVAIEAEDFGE 235
                        250       260
                 ....*....|....*....|..
gi 501404921 238 LGNSRDYAEGVDAFLNKRVAHF 259
Cdd:PRK05809 236 CFSTEDQTEGMTAFVEKREKNF 257
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
1-261 3.14e-29

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 110.90  E-value: 3.14e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQ-RARALILTGAG-RGFCAGQDLSELnftpGQMTD 78
Cdd:PRK06494   1 MALPFSTVERKGHVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADpEQWVAIVTGAGdKAFSAGNDLKEQ----AAGGK 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  79 LGqlIDEQ-FNPLVRRLrAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVA 157
Cdd:PRK06494  77 RG--WPESgFGGLTSRF-DLDKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRQIGLK 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 158 RSMGLAMLGEKLDAKTALAWGLIWGVYHDAKiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERD--LQ 235
Cdd:PRK06494 154 RAMGMILTGRRVTAREGLELGFVNEVVPAGE-LLAAAERWADDILACSPLSIRASKQAVYRGLEVSLEEAITAQRDypAV 232
                        250       260
                 ....*....|....*....|....*.
gi 501404921 236 RELGNSRDYAEGVDAFLNKRVAHFTG 261
Cdd:PRK06494 233 EARRASQDYIEGPKAFAEKRPPRWKG 258
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
1-260 4.76e-29

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 110.52  E-value: 4.76e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAGRGFCAGQDLSE---LNFTPGQM 76
Cdd:PRK05862   1 MAYETILVETRGRVGLITLNRPKALNALNDALMDELGAALAAFDADEGiGAIVITGSEKAFAAGADIKEmadLSFMDVYK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  77 TDLGQLIDEqfnplVRRLRAmplPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGV 156
Cdd:PRK05862  81 GDYITNWEK-----VARIRK---PVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGK 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 157 ARSMGLAMLGEKLDAKTALAWGLIWGVYHDAKiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQR 236
Cdd:PRK05862 153 AKAMDLCLTGRMMDAAEAERAGLVSRVVPADK-LLDEALAAATTIASFSLPAVMMAKEAVNRAYETTLAEGLLFERRLFH 231
                        250       260
                 ....*....|....*....|....
gi 501404921 237 ELGNSRDYAEGVDAFLNKRVAHFT 260
Cdd:PRK05862 232 SLFATEDQKEGMAAFVEKRKPVFK 255
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
2-259 6.33e-29

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 109.97  E-value: 6.33e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   2 TSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQR-ARALILTGAGRGFCAGQDLSELNFTPGQMT-DL 79
Cdd:PRK07509   1 MMDRVSVTIEDGIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRgIRAVILSGEGGAFCAGLDVKSVASSPGNAVkLL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  80 GQLIDEQFNpLVRRL----RAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIG 155
Cdd:PRK07509  81 FKRLPGNAN-LAQRVslgwRRLPVPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTVSLRGLVR 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 156 VARSMGLAMLGEKLDAKTALAWGLIWGVYHDAkilMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQ 235
Cdd:PRK07509 160 KDVARELTYTARVFSAEEALELGLVTHVSDDP---LAAALALAREIAQRSPDAIAAAKRLINRSWTASVRALLARESVEQ 236
                        250       260
                 ....*....|....*....|....
gi 501404921 236 RELGNSRDYAEGVDAFLNKRVAHF 259
Cdd:PRK07509 237 IRLLLGKNQKIAVKAQMKKRAPKF 260
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
3-262 2.99e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 108.28  E-value: 2.99e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   3 SPTILLDWHE-HVATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAG-RGFCAGQDLSE-LNFTPGQMTD 78
Cdd:PRK07657   2 LQNISVDYVTpHVVKITLNRPRAANALSLALLEELQNILTQINEEANvRVVILTGAGeKAFCAGADLKErAGMNEEQVRH 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  79 LGQLIDEQFNplvrRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVAR 158
Cdd:PRK07657  82 AVSLIRTTME----MVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGR 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 159 SMGLAMLGEKLDAKTALAWGLIWGVYHDAKiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQREL 238
Cdd:PRK07657 158 AKELIYTGRRISAQEAKEIGLVEFVVPAHL-LEEKAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIEKQAYEGT 236
                        250       260
                 ....*....|....*....|....
gi 501404921 239 GNSRDYAEGVDAFLNKRVAHFTGE 262
Cdd:PRK07657 237 IPTKDRLEGLQAFKEKRKPMYKGE 260
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
3-255 4.48e-28

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 107.92  E-value: 4.48e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   3 SPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAG-RGFCAGQDLSELNFTPGQMTDL- 79
Cdd:PRK05980   2 TDTVLIEIRDGIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESvRAVILTGAGdRAFSAGADIHEFSASVAAGADVa 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  80 -------GQlideqfnPLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQ 152
Cdd:PRK05980  82 lrdfvrrGQ-------AMTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPR 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 153 RIGVARSMGLAMLGEKLDAKTALAWGLIWGVY-HDAkiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLE 231
Cdd:PRK05980 155 LAGRKRALELLLTGDAFSAERALEIGLVNAVVpHEE--LLPAARALARRIIRHSPVAVAAILTAVTRGLNLSIAEGLLIE 232
                        250       260
                 ....*....|....*....|....
gi 501404921 232 RDLQRELGNSRDYAEGVDAFLNKR 255
Cdd:PRK05980 233 SEQFARMAGSADLREGLAAWIERR 256
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
2-262 2.25e-27

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 105.84  E-value: 2.25e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   2 TSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVE-RQRARALILTGAGRGFCAGQDLSelNFTPGQMTDL- 79
Cdd:PRK08252   1 MSDEVLVERRGRVLIITINRPEARNAVNAAVAQGLAAALDELDaDPDLSVGILTGAGGTFCAGMDLK--AFARGERPSIp 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  80 --GqlideqFNPLVRRLRAMPLpvIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVA 157
Cdd:PRK08252  79 grG------FGGLTERPPRKPL--IAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLPRRIPYH 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 158 RSMGLAMLGEKLDAKTALAWGLIWGVYHDAKILMTEVNcMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRE 237
Cdd:PRK08252 151 IAMELALTGDMLTAERAHELGLVNRLTEPGQALDAALE-LAERIAANGPLAVAASKRIVVESGDWSEDEMFARQRELIAP 229
                        250       260
                 ....*....|....*....|....*
gi 501404921 238 LGNSRDYAEGVDAFLNKRVAHFTGE 262
Cdd:PRK08252 230 VFTSADAKEGATAFAEKRAPVWTGK 254
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
1-262 2.96e-27

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 105.78  E-value: 2.96e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAGRGFCAGQDLSELNfTPGQMTDL 79
Cdd:PRK05995   1 MMYETLEIEQRGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSvRAVVLAGAGKAFCAGADLNWMK-KMAGYSDD 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  80 GQLIDEQ-FNPLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPdsggTWFLPQrigVAR 158
Cdd:PRK05995  80 ENRADARrLADMLRAIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIP----ATISPY---VIR 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 159 SMG------LAMLGEKLDAKTALAWGLIWGVYH----DAKilmteVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQL 228
Cdd:PRK05995 153 AMGeraarrYFLTAERFDAAEALRLGLVHEVVPaealDAK-----VDELLAALVANSPQAVRAGKRLVRDVAGRPIDAAL 227
                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 501404921 229 dLERDLQR--ELGNSRDYAEGVDAFLNKRVAHFTGE 262
Cdd:PRK05995 228 -IADTASRiaLIRATEEAREGVAAFLEKRKPAWRGR 262
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
1-262 2.78e-26

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 103.10  E-value: 2.78e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAGRGFCAGQDLSELNFTPGQmtdl 79
Cdd:PRK08139   8 TEAPLLLREDRDGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSvRVVVLAAAGKAFCAGHDLKEMRAARGL---- 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  80 gqlidEQFNPLVRR-------LRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLpdsGGTWFLPQ 152
Cdd:PRK08139  84 -----AYFRALFARcsrvmqaIVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLF---CSTPMVAL 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 153 RIGVARSMGLAML--GEKLDAKTALAWGLI-WGVYHDAkiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLD 229
Cdd:PRK08139 156 SRNVPRKQAMEMLltGEFIDAATAREWGLVnRVVPADA--LDAAVARLAAVIAAKSPAAVRIGKEAFYRQAEMPLADAYA 233
                        250       260       270
                 ....*....|....*....|....*....|...
gi 501404921 230 LERDLQRELGNSRDYAEGVDAFLNKRVAHFTGE 262
Cdd:PRK08139 234 YAGDVMAENMMAEDAEEGIDAFLEKRPPEWRGR 266
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
1-262 3.73e-25

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 100.15  E-value: 3.73e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPtILLDWHEHVATITLNRPdQLNSFTAGMHRELREA-LDKVERQRARALILTGAG-RGFCAGQDLSELNftpgqmtd 78
Cdd:PRK03580   1 MSES-LHTTRNGSILEITLDRP-KANAIDAKTSFAMGEVfLNFRDDPELRVAIITGAGeKFFSAGWDLKAAA-------- 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  79 LGQLIDEQFNPL----VRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRI 154
Cdd:PRK03580  71 EGEAPDADFGPGgfagLTEIFDLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKRL 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 155 GVARSMGLAMLGEKLDAKTALAWGLIWGVYHDAKiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDL 234
Cdd:PRK03580 151 PPAIANEMVMTGRRMDAEEALRWGIVNRVVPQAE-LMDRARELAQQLVNSAPLAIAALKEIYRETSEMPVEEAYRYIRSG 229
                        250       260       270
                 ....*....|....*....|....*....|..
gi 501404921 235 Q----RELGNSRDYAEGVDAFLNKRVAHFTGE 262
Cdd:PRK03580 230 VlkhyPSVLHSEDALEGPRAFAEKRDPVWKGR 261
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
1-262 5.50e-25

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 99.72  E-value: 5.50e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQRARALILtGAGRG---FCAGQDLSELNfTPGQmT 77
Cdd:PRK11423   1 MSMQYVNVVTINKIATITFNNPAKRNALSKVLIDDLMQALSDLNRPEIRVVIL-RAPSGskvWSAGHDIHELP-SGGR-D 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  78 DLGQliDEQFNPLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIG-- 155
Cdd:PRK11423  78 PLSY--DDPLRQILRMIQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSGILNFTNDAGfh 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 156 VARSMglAMLGEKLDAKTALAWGLIWGVYhDAKILMTEVNCMADHLAKQPTRALAAIKRAMHA-APTQSLDAQLdLER-- 232
Cdd:PRK11423 156 IVKEM--FFTASPITAQRALAVGILNHVV-EVEELEDFTLQMAHHISEKAPLAIAVIKEQLRVlGEAHPMNPDE-FERiq 231
                        250       260       270
                 ....*....|....*....|....*....|
gi 501404921 233 DLQRELGNSRDYAEGVDAFLNKRVAHFTGE 262
Cdd:PRK11423 232 GLRRAVYDSEDYQEGMNAFLEKRKPVFVGH 261
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
12-261 7.43e-25

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 99.66  E-value: 7.43e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  12 EHVATITLNRPDQLNSFTAGMHRELREALDKVERQR-ARALILTGAGRGFCAGQDLSELNFTPGQM-TDLGQLIDEQFNP 89
Cdd:PRK06142  14 DHVAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPeVRAVVLSGSGKHFSYGIDLPAMAGVFGQLgKDGLARPRTDLRR 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  90 LVRRLRAM-------PLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARSMGL 162
Cdd:PRK06142  94 EILRLQAAinavadcRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQRLPRIIGDGHLREL 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 163 AMLGEKLDAKTALAWGLIWGVYHDAKILMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRELGNSR 242
Cdd:PRK06142 174 ALTGRDIDAAEAEKIGLVNRVYDDADALLAAAHATAREIAAKSPLAVRGTKEVLDYMRDHRVADGLRYVATWNAAMLPSK 253
                        250
                 ....*....|....*....
gi 501404921 243 DYAEGVDAFLNKRVAHFTG 261
Cdd:PRK06142 254 DLTEAIAAHMEKRPPEFTG 272
PLN02888 PLN02888
enoyl-CoA hydratase
13-247 1.10e-24

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 99.06  E-value: 1.10e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  13 HVATITLNRPDQLNSFTAGMHRELREALDKV-ERQRARALILTGAGRGFCAGQDLselnfTPGQMTDLGQLIDEQFNPLV 91
Cdd:PLN02888  19 GIATITINRPKALNALTRPMMVELAAAFKRLdEDDSVKVIILTGSGRAFCSGVDL-----TAAEEVFKGDVKDVETDPVA 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  92 R--RLRAmplPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARSMGLAMLGEKL 169
Cdd:PLN02888  94 QmeRCRK---PIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANRAREVSLTAMPL 170
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 501404921 170 DAKTALAWGLIWGVYHDAKILMTEVNcMADHLAKQPTRALAAIKRAMHAAptqsldAQLDLERDLQRELGNSRDYAEG 247
Cdd:PLN02888 171 TAETAERWGLVNHVVEESELLKKARE-VAEAIIKNNQGMVLRYKSVINDG------LKLDLGHALQLEKERAHDYYNG 241
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
13-261 2.59e-24

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 97.72  E-value: 2.59e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  13 HVATITLNRPDQLNSFTAGMHRELREALDKVER-QRARALILTGAGRGFCAGQDLSElnFTPGQMTDLGQLIDEQFNPLV 91
Cdd:PRK06563   8 HVLLIGLDRPAKRNAFDSAMLDDLALALGEYEAdDELRVAVLFAHGEHFTAGLDLAD--VAPKLAAGGFPFPEGGIDPWG 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  92 RRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARSMGLAMLGEKLDA 171
Cdd:PRK06563  86 TVGRRLSKPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILPFGGATLRFPQAAGWGNAMRYLLTGDEFDA 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 172 KTALAWGLIWGVYHDAKILMTEVNcMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRELGNSRDYAEGVDAF 251
Cdd:PRK06563 166 QEALRLGLVQEVVPPGEQLERAIE-LAERIARAAPLGVQATLASARAAVREGEAAAAAQLPPELRPLFTSEDAKEGVQAF 244
                        250
                 ....*....|
gi 501404921 252 LNKRVAHFTG 261
Cdd:PRK06563 245 LERRPARFKG 254
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
5-261 6.44e-24

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 96.69  E-value: 6.44e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   5 TILLDWHEHVATITLNRPdQLNSFTAGMHRELREALDKV-ERQRARALILTGAGRGFCAGQDL---SELNFTPGQMTDLG 80
Cdd:PRK06495   5 QLKLEVSDHVAVVTLDNP-PVNALSRELRDELIAVFDEIsERPDVRVVVLTGAGKVFCAGADLkgrPDVIKGPGDLRAHN 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  81 QLIDEQFNPLvrrlRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLpdsGGTWFLPQRIGVARSM 160
Cdd:PRK06495  84 RRTRECFHAI----RECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGLA---GGGKHAMRLFGHSLTR 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 161 GLAMLGEKLDAKTALAWGLIWG-VYHDAkiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRELG 239
Cdd:PRK06495 157 RMMLTGYRVPAAELYRRGVIEAcLPPEE--LMPEAMEIAREIASKSPLATRLAKDALNTIENMSLRDGYRYEQDITAKLA 234
                        250       260
                 ....*....|....*....|..
gi 501404921 240 NSRDYAEGVDAFLNKRVAHFTG 261
Cdd:PRK06495 235 KTEDAKEAQRAFLEKRPPVFKG 256
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
1-262 6.97e-23

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 94.01  E-value: 6.97e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAGRGFCAGQDLSELNFT-PGQMTD 78
Cdd:PRK07799   2 EGGPHALVEQRGHTLIVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDiRSCILTGAGGAFCAGMDLKAATKKpPGDSFK 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  79 LGQLIDEQFNPLV--RRLRAmplPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGV 156
Cdd:PRK07799  82 DGSYDPSRIDALLkgRRLTK---PLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAVRLVRQIPY 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 157 ARSMGLAMLGEKLDAKTALAWGLIWGVYHDAKILmTEVNCMADHLAKQPTRALAAIKRAMHAapTQSLDAQLDLERDLQR 236
Cdd:PRK07799 159 TVACDLLLTGRHITAAEAKEIGLIGHVVPDGQAL-DKALELAELINANGPLAVQAILRTIRE--TEGMHENEAFKIDTKI 235
                        250       260
                 ....*....|....*....|....*...
gi 501404921 237 --ELGNSRDYAEGVDAFLNKRVAHFTGE 262
Cdd:PRK07799 236 giPVFLSEDAKEGPRAFAEKRAPNFQGR 263
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
5-255 1.08e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 93.44  E-value: 1.08e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   5 TILLDW--HEHVATITLNRPDQlNSFTAGMHRELREALDKV-ERQRARALILTGAG-RGFCAGQDLSelNFTPGqmtDLG 80
Cdd:PRK09076   2 MIELDLeiDGHVAILTLNNPPA-NTWTADSLQALKQLVLELnADKDVYALVITGDGeKFFSAGADLN--LFADG---DKA 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  81 QLID--EQFNPLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGV-- 156
Cdd:PRK09076  76 VAREmaRRFGEAFEALSAFRGVSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVGEgw 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 157 ARSMGLamLGEKLDAKTALAWGLIWGVYHDAKILMTEVNcMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQR 236
Cdd:PRK09076 156 AKRMIL--CGERVDAATALRIGLVEEVVEKGEAREAALA-LAQKVANQSPSAVAACKTLIQAARNGPRAAALALERELFV 232
                        250
                 ....*....|....*....
gi 501404921 237 ELGNSRDYAEGVDAFLNKR 255
Cdd:PRK09076 233 DLFDTEDQREGVNAFLEKR 251
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
1-258 1.98e-22

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 92.82  E-value: 1.98e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDW-HEHVATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAGRGFCAGQDLSELNftpGQMT- 77
Cdd:PRK07468   1 MMFETIRIAVdARGVATLTLNRPEKHNALSARMIAELTTAARRLAADAAvRVVVLTGAGKSFCAGGDLGWMR---AQMTa 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  78 DLGQLIDE--QFNPLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLpQRIG 155
Cdd:PRK07468  78 DRATRIEEarRLAMMLKALNDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVV-ARMG 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 156 VARSMGLAMLGEKLDAKTALAWGLIWGVYHDAKI---LMTEVncmADHLAKQPTrALAAIKRAMHAAPTQSLDAQLDLER 232
Cdd:PRK07468 157 EANARRVFMSARLFDAEEAVRLGLLSRVVPAERLdaaVEAEV---TPYLSCAPG-AVAAAKALVRALGAPIDEAVIDATI 232
                        250       260
                 ....*....|....*....|....*.
gi 501404921 233 DLQRELGNSRDYAEGVDAFLNKRVAH 258
Cdd:PRK07468 233 EALADTWETEEAREGIAAFFDKRAPA 258
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
1-261 1.17e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 90.82  E-value: 1.17e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAG-RGFCAGQDLSEL-NFTPGQ-M 76
Cdd:PRK06144   5 TSTDELLLEVRGGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSiRAVVLRGAGdKAFVAGTDIAQFrAFSTAEdA 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  77 TDLGQLIDEqfnpLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENAcflqafvKIGL---------LPDSGGT 147
Cdd:PRK06144  85 VAYERRIDR----VLGALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSA-------RFGFpiartlgncLSMSNLA 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 148 WfLPQRIGVARSMGLAMLGEKLDAKTALAWGLIWGVYHDAkILMTEVNCMADHLAKQPTRALAAIKRAMHaaptQSLDAQ 227
Cdd:PRK06144 154 R-LVALLGAARVKDMLFTARLLEAEEALAAGLVNEVVEDA-ALDARADALAELLAAHAPLTLRATKEALR----RLRREG 227
                        250       260       270
                 ....*....|....*....|....*....|....
gi 501404921 228 LDLERDLQRELGNSRDYAEGVDAFLNKRVAHFTG 261
Cdd:PRK06144 228 LPDGDDLIRMCYMSEDFREGVEAFLEKRPPKWKG 261
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
5-255 1.42e-21

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 90.84  E-value: 1.42e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   5 TILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVE-RQRARALILTGAGRGFCAGQDLSELNFTPGQMTDLGQL- 82
Cdd:PRK09120   9 TVKVEVEDGIAWVTLNRPEKRNAMSPTLNREMIDVLDALEfDDDAGVLVLTGAGDAWSAGMDLKEYFRETDAQPEILQEr 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  83 IDEQFNPLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARSMGL 162
Cdd:PRK09120  89 IRREAYGWWRRLRWYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKAMADTVGHRDALYY 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 163 AMLGEKLDAKTALAWGLI-WGVYHDAkiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLD-LERDLQ--REL 238
Cdd:PRK09120 169 IMTGETFTGRKAAEMGLVnESVPLAQ--LRARTRELAAKLLEKNPVVLRAAKDGFKRVRELTWDQAEDyLYAKLEqaNSL 246
                        250
                 ....*....|....*..
gi 501404921 239 GNSRDYAEGVDAFLNKR 255
Cdd:PRK09120 247 DPEGGREEGLKQFLDDK 263
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
1-219 1.70e-20

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 88.56  E-value: 1.70e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVE-RQRARALILTGAGRGFCAGQDLSEL---------- 69
Cdd:PRK08272   7 DNLKTMTYEVTGRIARITLNRPEKGNAITADTPLELRAAVERADlDPGVHVILVSGAGKGFCAGYDLSAYaegsssgggg 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  70 NFTPGQMTDLGQLIDEQFNPLV------------RRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENAcflqafvK 137
Cdd:PRK08272  87 GAYPGKRQAVNHLPDDPWDPMIdyqmmsrfvrgfMSLWHAHKPTVAKVHGYCVAGGTDIALHCDQVIAADDA-------K 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 138 IGLLPD------SGGTWFlpQRIGVARSMGLAMLGEKLDAKTALAWGLIWGVYhDAKILMTEVNCMADHLAKQPTRALAA 211
Cdd:PRK08272 160 IGYPPTrvwgvpATGMWA--YRLGPQRAKRLLFTGDCITGAQAAEWGLAVEAV-PPEELDERTERLVERIAAVPVNQLAM 236

                 ....*...
gi 501404921 212 IKRAMHAA 219
Cdd:PRK08272 237 VKLAVNSA 244
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
14-255 1.61e-19

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 85.12  E-value: 1.61e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  14 VATITLNRPDQLNSFTAGMHRELREALDKV-ERQRARALILTGAGRGFCAGQDLSELNFTPGQMTDLGQLIDEQFNPLVR 92
Cdd:PRK07827  16 VATLTLDSPHNRNALSARLVAQLHDGLRAAaADPAVRAVVLTHTGGTFCAGADLSEAGGGGGDPYDAAVARAREMTALLR 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  93 RLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRigVARSMGLAML-GEKLDA 171
Cdd:PRK07827  96 AIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRL--SPRAAARYYLtGEKFGA 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 172 KTALAWGLIWGVYHDakiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRELGNSRDYAEGVDAF 251
Cdd:PRK07827 174 AEAARIGLVTAAADD---VDAAVAALLADLRRGSPQGLAESKALTTAAVLAGFDRDAEELTEESARLFVSDEAREGMTAF 250

                 ....
gi 501404921 252 LNKR 255
Cdd:PRK07827 251 LQKR 254
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
11-254 5.40e-19

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 83.30  E-value: 5.40e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  11 HEHVATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAGRGFCAGQDLSE-LNFTPGQMTDLGQLIDeqfn 88
Cdd:PRK06023  13 HPGVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAiRAHVFLGTEGCFSAGNDMQDfLAAAMGGTSFGSEILD---- 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  89 pLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARSMGLAMLGEK 168
Cdd:PRK06023  89 -FLIALAEAEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMGHQRAFALLALGEG 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 169 LDAKTALAWGLIWGVYhDAKILMTEVNCMADHLAKQPTRALaAIKRAMHAAPTQSLDAQLDLERDLQRELGNSRDYAEGV 248
Cdd:PRK06023 168 FSAEAAQEAGLIWKIV-DEEAVEAETLKAAEELAAKPPQAL-QIARDLMRGPREDILARIDEEAKHFAARLKSAEARAAF 245

                 ....*.
gi 501404921 249 DAFLNK 254
Cdd:PRK06023 246 EAFMRR 251
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
12-261 5.81e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 83.15  E-value: 5.81e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  12 EHVATITLNRPDQLNSFTAGMHRELREALDKVERQRARALILTGAGRGFCAGQDLSelnftpgqmtdlGQLIDEQF-NPL 90
Cdd:PRK07854   8 GQVLTIELQRPERRNALNAELCEELREAVRKAVDESARAIVLTGQGTVFCAGADLS------------GDVYADDFpDAL 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  91 VRRLRAM---PLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSggtWFLpQRI------GVARSMG 161
Cdd:PRK07854  76 IEMLHAIdaaPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALDN---WTI-RRLsslvggGRARAML 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 162 LAmlGEKLDAKTALAWGLIW--GVYHDAKILMTEVncmadhlAKQPTRALAAIKRAMHAAPTQslDAQLDLERDLQRELG 239
Cdd:PRK07854 152 LG--AEKLTAEQALATGMANriGTLADAQAWAAEI-------AGLAPLALQHAKRVLNDDGAI--EEAWPAHKELFDKAW 220
                        250       260
                 ....*....|....*....|..
gi 501404921 240 NSRDYAEGVDAFLNKRVAHFTG 261
Cdd:PRK07854 221 ASQDAIEAQVARIEKRPPKFQG 242
PLN02921 PLN02921
naphthoate synthase
12-260 1.61e-17

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 80.60  E-value: 1.61e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  12 EHVATITLNRPDQLNSFTAGMHRELREAL-DKVERQRARALILTGAG-RGFCAGQDLSELNFTPGQMTD-LGQL--IDEQ 86
Cdd:PLN02921  75 EGIAKITINRPERRNAFRPRTVKELQRAFnDARDDSSVGVIILTGKGtKAFCSGGDQAVRGKDGYVGPDdAGRLnvLDLQ 154
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  87 FnplvrRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLpDSG-GTWFLPQRIGVARSMGLAML 165
Cdd:PLN02921 155 I-----QIRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSF-DAGyGSSIMARLVGQKKAREMWFL 228
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 166 GEKLDAKTALAWGLIWGVYHDAKILMTEVNCMADHLAKQPTrALAAIKRAMHAAPTQSLDAQlDLERDLQRELGNSRDYA 245
Cdd:PLN02921 229 ARFYTASEALKMGLVNTVVPLDELEGETVKWCREILRNSPT-AIRVLKSALNAADDGHAGLQ-ELGGNATLLFYGSEEGN 306
                        250
                 ....*....|....*
gi 501404921 246 EGVDAFLNKRVAHFT 260
Cdd:PLN02921 307 EGRTAYLEGRAPDFS 321
PLN02600 PLN02600
enoyl-CoA hydratase
14-262 1.77e-17

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 79.08  E-value: 1.77e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  14 VATITLNRPDQLNSFTAGMHRELREALDKVERQ-RARALILTGAGRG-FCAGQDLSELN-FTPGQMTDLGQLIDEQFNpl 90
Cdd:PLN02600   5 IVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADaSARVVMLRSSVPGvFCAGADLKERRkMSPSEVQKFVNSLRSTFS-- 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  91 vrRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARSMGLAMLGEKLD 170
Cdd:PLN02600  83 --SLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 171 AKTALAWGLI-----WGVYHDAKILmtevncMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRELGNSRDYA 245
Cdd:PLN02600 161 AREAASMGLVnycvpAGEAYEKALE------LAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRL 234
                        250
                 ....*....|....*..
gi 501404921 246 EGVDAFLNKRVAHFTGE 262
Cdd:PLN02600 235 EGLAAFAEKRKPVYTGK 251
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
13-260 2.18e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 79.49  E-value: 2.18e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  13 HVATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAGRGFCAGQDLSELNFTPgQMTDLGQ---------L 82
Cdd:PRK05864  19 EIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSvRVVVLTGAGRGFSSGADHKSAGVVP-HVEGLTRptyalrsmeL 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  83 IDEqfnpLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDS-GGTWFLPQRIGVARSMG 161
Cdd:PRK05864  98 LDD----VILALRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTASElGLSYLLPRAIGSSRAFE 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 162 LAMLGEKLDAKTALAWGLIWGVYHDAKILMTevnC--MADHLAKQPTRALAAIKRAMHAAptqsLDAQlDLERDLQRE-L 238
Cdd:PRK05864 174 IMLTGRDVDAEEAERIGLVSRQVPDEQLLDT---CyaIAARMAGFSRPGIELTKRTLWSG----LDAA-SLEAHMQAEgL 245
                        250       260
                 ....*....|....*....|....*...
gi 501404921 239 GN------SRDYAEGVDAFLNKRVAHFT 260
Cdd:PRK05864 246 GQlfvrllTANFEEAVAARAEKRPPVFT 273
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
1-227 3.20e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 79.23  E-value: 3.20e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAGRGFCAGQDLS------ELNFTP 73
Cdd:PRK08290   1 MEYEYVRYEVAGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAvRVIVLAGAGKHFSAGHDLGsgtpgrDRDPGP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  74 GQMTDLG----------QLID---EQFNPLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGL 140
Cdd:PRK08290  81 DQHPTLWwdgatkpgveQRYArewEVYLGMCRRWRDLPKPTIAQVQGACIAGGLMLAWVCDLIVASDDAFFSDPVVRMGI 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 141 lpdsGG------TWFLPQRIgvARSMGLamLGEKLDAKTALAWGLIWGVYHDAKiLMTEVNCMADHLAKQPTRALAAIKR 214
Cdd:PRK08290 161 ----PGveyfahPWELGPRK--AKELLF--TGDRLTADEAHRLGMVNRVVPRDE-LEAETLELARRIAAMPPFGLRLTKR 231
                        250
                 ....*....|...
gi 501404921 215 AMHaaptQSLDAQ 227
Cdd:PRK08290 232 AVN----QTLDAQ 240
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
14-255 4.91e-17

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 78.31  E-value: 4.91e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  14 VATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAGRGFCAGQDLSELNftpgQMTDL---GQLIDEQ-FN 88
Cdd:PRK05674  16 FATLWLSRADKNNAFNAQMIRELILALDQVQSDASlRFLLLRGRGRHFSAGADLAWMQ----QSADLdynTNLDDAReLA 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  89 PLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTwFLPQRIGVARSMGLAMLGEK 168
Cdd:PRK05674  92 ELMYNLYRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAVISP-FVVKAIGERAARRYALTAER 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 169 LDAKTALAWGLIWGVYHDAKiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAqlDLERDLQRELGNSRDYA--- 245
Cdd:PRK05674 171 FDGRRARELGLLAESYPAAE-LEAQVEAWIANLLLNSPQALRASKDLLREVGDGELSP--ALRRYCENAIARIRVSAegq 247
                        250
                 ....*....|
gi 501404921 246 EGVDAFLNKR 255
Cdd:PRK05674 248 EGLRAFLEKR 257
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
6-259 7.30e-17

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 78.01  E-value: 7.30e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   6 ILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKV-ERQRARALILTGAG-RGFCAGQDLSelnfTPGQmtdlGQLI 83
Cdd:PRK07396  15 ILYKSADGIAKITINRPEVRNAFRPKTVKEMIDAFADArDDDNIGVIILTGAGdKAFCSGGDQK----VRGY----GGYV 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  84 DEQFNP------LVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLpDSG-GTWFLPQRIGV 156
Cdd:PRK07396  87 DDDGVPrlnvldLQRLIRTCPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSF-DGGyGASYLARIVGQ 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 157 ARSMGLAMLGEKLDAKTALAWGLIWGVYHDAKILMTEVNCMADHLAKQPTrALAAIKRAMHaaptqsldAQLDLERDLQR 236
Cdd:PRK07396 166 KKAREIWFLCRQYDAQEALDMGLVNTVVPLADLEKETVRWCREMLQNSPM-ALRCLKAALN--------ADCDGQAGLQE 236
                        250       260       270
                 ....*....|....*....|....*....|
gi 501404921 237 ELGN-------SRDYAEGVDAFLNKRVAHF 259
Cdd:PRK07396 237 LAGNatmlfymTEEAQEGRNAFNEKRQPDF 266
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
5-261 1.38e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 77.05  E-value: 1.38e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   5 TILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVE-RQRARALILTGAG-RGFCAGQDLS---ELNFTPGQMTDL 79
Cdd:PRK06127  12 KLLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEdDDAIRVVVLTGAGeKAFVSGADISqfeESRSDAEAVAAY 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  80 GQLIDEQFNPLVrrlrAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARS 159
Cdd:PRK06127  92 EQAVEAAQAALA----DYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVDLVGPSAA 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 160 MGLAMLGEKLDAKTALAWGLIWGVYHDAKiLMTEVNCMADHLAKQPTRALAAIKRAMhaAPTQSLDAQLDLE--RDLQRE 237
Cdd:PRK06127 168 KDLFYTARRFDAAEALRIGLVHRVTAADD-LETALADYAATIAGNAPLTLRAAKRAI--AELLKDEPERDMAacQALVAA 244
                        250       260
                 ....*....|....*....|....
gi 501404921 238 LGNSRDYAEGVDAFLNKRVAHFTG 261
Cdd:PRK06127 245 CFDSEDYREGRAAFMEKRKPVFKG 268
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
14-230 1.45e-16

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 77.90  E-value: 1.45e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   14 VATITLNRPDQLNSFTAGMHRELREALDKVER-QRARALILTGAG-RGFCAGQDLSEL--NFTPGQMTDLGQLIDEQFNp 89
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDdPAVKLVVLKGAGeRAFCAGGDVRALyeAAKAGGGEAGRDFFREEYR- 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   90 LVRRLRAMPLPVIaavngvaagaganlaLACD-IVM--------------AAENACFlqAF--VKIGLLPDSGGTWFLPQ 152
Cdd:pfam16113  80 LNYLIATYPKPYV---------------ALMDgIVMgggvglsvhgsfrvVTERTRF--AMpeTAIGLFPDVGGSYFLSR 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  153 ---RIGVArsmgLAMLGEKLDAKTALAWGLiwgvyhdakilmtevncmADHLAkqPTRALAAIKRAMHAAPTQSLDAQLD 229
Cdd:pfam16113 143 lpgELGLY----LALTGARLNGADALAAGL------------------ATHYV--PSARLPALEEALAALDWSDPADVDA 198

                  .
gi 501404921  230 L 230
Cdd:pfam16113 199 V 199
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
4-261 3.93e-16

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 75.83  E-value: 3.93e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   4 PTILLDWHEH-VATITLNRPDQLNSFTAGMHRELREALDKVER-QRARALILTGAGRGFCAGQDLSELNFTPGQMTDLGQ 81
Cdd:PRK07327  11 PALRFDRPPPgVLEIVLNGPGALNAADARMHRELADIWRDVDRdPDVRVVLIRGEGKAFSAGGDLALVEEMADDFEVRAR 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  82 LIDEQFNpLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARSMG 161
Cdd:PRK07327  91 VWREARD-LVYNVINCDKPIVSAIHGPAVGAGLVAALLADISIAAKDARIIDGHTRLGVAAGDHAAIVWPLLCGMAKAKY 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 162 LAMLGEKLDAKTALAWGLIWGVYHDAKILMTEVNcMADHLAKQPTRALAAIKRAMH-----AAPTqsLDAQLDLERdlqr 236
Cdd:PRK07327 170 YLLLCEPVSGEEAERIGLVSLAVDDDELLPKALE-VAERLAAGSQTAIRWTKYALNnwlrmAGPT--FDTSLALEF---- 242
                        250       260
                 ....*....|....*....|....*.
gi 501404921 237 eLG-NSRDYAEGVDAFLNKRVAHFTG 261
Cdd:PRK07327 243 -MGfSGPDVREGLASLREKRAPDFPG 267
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
14-230 4.13e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 75.46  E-value: 4.13e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  14 VATITLNRPDQLNSFTAGMHRELREALDKV-ERQRARALILTGAG-RGFCAGQDLSElnftpgqMTDLGQLIDEQFNPLV 91
Cdd:PRK06143  17 VATLTIRNAGSLNILGTPVILALTQALRWLaADPDVRVLVLRGAGeKAFIGGADIKE-------MATLDQASAEAFISRL 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  92 RRL----RAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGlLPDSGGTWFLPQRIGVARSMGLAMLGE 167
Cdd:PRK06143  90 RDLcdavRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVG-IPSVIHAALLPRLIGWARTRWLLLTGE 168
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 501404921 168 KLDAKTALAWGLI-WGVYHDAkiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDL 230
Cdd:PRK06143 169 TIDAAQALAWGLVdRVVPLAE--LDAAVERLAASLAGCGPQALRQQKRLLREWEDMPLDVAIDD 230
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
14-260 6.05e-16

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 75.32  E-value: 6.05e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  14 VATITLNRPDQLNSFTAGMHRELREALDKVERQ-RARALILTGAGRGFCAGQDLSELN--FTPGQMTDLGQlIDEQFNPL 90
Cdd:PLN02664  18 VFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNpNVSVIILSGAGDHFCSGIDLKTLNsiSEQSSSGDRGR-SGERLRRK 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  91 VRRLRAMPL-------PVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARSMGLA 163
Cdd:PLN02664  97 IKFLQDAITaieqcrkPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGTLQRLPSIVGYGNAMELA 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 164 MLGEKLDAKTALAWGLIWGVYHDAKILMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRELGNSRD 243
Cdd:PLN02664 177 LTGRRFSGSEAKELGLVSRVFGSKEDLDEGVRLIAEGIAAKSPLAVTGTKAVLLRSRELSVEQGLDYVATWNSAMLVSDD 256
                        250
                 ....*....|....*..
gi 501404921 244 YAEGVDAFLNKRVAHFT 260
Cdd:PLN02664 257 LNEAVSAQIQKRKPVFA 273
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
5-229 8.95e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 72.30  E-value: 8.95e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   5 TILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVER-QRARALILTGAGRGFCAGQDL-------SELNFTPGQM 76
Cdd:PRK12478   6 TLLYTTAGPVATITLNRPEQLNTIVPPMPDEIEAAIGLAERdQDIKVIVLRGAGRAFSGGYDFgggfqhwGEAMMTDGRW 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  77 ---TDLGQLIDEQFNPlVRRLRAM---PLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKI--GLLPdsgGTW 148
Cdd:PRK12478  86 dpgKDFAMVTARETGP-TQKFMAIwraSKPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTPYSRMwgAYLT---GMW 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 149 FlpQRIGVARSMGLAMLGEKLDAKTALAWGLIwgvyHDA---KILMTEVNCMADHLAKQPTRALAAIK-------RAMHA 218
Cdd:PRK12478 162 L--YRLSLAKVKWHSLTGRPLTGVQAAEAELI----NEAvpfERLEARVAEVATELARIPLSQLQAQKlivnqayENMGL 235
                        250
                 ....*....|.
gi 501404921 219 APTQSLDAQLD 229
Cdd:PRK12478 236 ASTQTLGGILD 246
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
1-239 4.81e-13

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 66.92  E-value: 4.81e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVER-QRARALILTGAGRGFCAG---QDLSELNFTPGQM 76
Cdd:PRK07110   2 MMKVVELREVEEGIAQVTMQDRVNKNAFSDELCDQLHEAFDTIAQdPRYKVVILTGYPNYFATGgtqEGLLSLQTGKGTF 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  77 TDLgqlideqfnPLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGV 156
Cdd:PRK07110  82 TEA---------NLYSLALNCPIPVIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPEKLGL 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 157 ArsMGLAML-------GEKLDAKtalawGLIWGVYHDAKILMTEVNcMADHLAKQPTRALAAIKRAMhaaptqSLDAQLD 229
Cdd:PRK07110 153 A--LGQEMLltaryyrGAELKKR-----GVPFPVLPRAEVLEKALE-LARSLAEKPRHSLVLLKDHL------VADRRRR 218
                        250
                 ....*....|
gi 501404921 230 LERDLQRELG 239
Cdd:PRK07110 219 LPEVIEQEVA 228
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
11-179 2.84e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 64.65  E-value: 2.84e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  11 HEHVATITLNRPDQLNSFTAGMHRELREALDKVERQrARALILTGAGRGFCAGQDLSEL-NFTPGQMTDLGQLIDEQFNp 89
Cdd:PRK08150   9 DGGVATIGLNRPAKRNALNDGLIAALRAAFARLPEG-VRAVVLHGEGDHFCAGLDLSELrERDAGEGMHHSRRWHRVFD- 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  90 lvrRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARSMGLAMLGEKL 169
Cdd:PRK08150  87 ---KIQYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGVARMTDMMLTGRVY 163
                        170
                 ....*....|
gi 501404921 170 DAKTALAWGL 179
Cdd:PRK08150 164 DAQEGERLGL 173
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
1-180 5.58e-12

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 63.93  E-value: 5.58e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVERQrARALILTGAGRGFCAGQDLSELNftpgQMTDLG 80
Cdd:PRK07112   1 MDYQTIRVRQQGDVCFLQLHRPEAQNTINDRLIAECMDVLDRCEHA-ATIVVLEGLPEVFCFGADFSAIA----EKPDAG 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  81 QliDEQFNP-----LVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPdSGGTWFLPQRIG 155
Cdd:PRK07112  76 R--ADLIDAeplydLWHRLATGPYVTIAHVRGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIP-ACVLPFLIRRIG 152
                        170       180
                 ....*....|....*....|....*
gi 501404921 156 VARSMGLAMLGEKLDAKTALAWGLI 180
Cdd:PRK07112 153 TQKAHYMTLMTQPVTAQQAFSWGLV 177
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
13-229 9.80e-11

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 60.99  E-value: 9.80e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  13 HVATITLNRPDQLNSFTAGMHRELREALDKVERQRA-RALILTGAG-RGFCAGQDLSELNftPGQMTDLGQLIDEQFN-- 88
Cdd:PRK05617  12 GVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAvAAVVIEGAGeRGFCAGGDIRALY--EAARAGDPLAADRFFRee 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  89 -PLVRRLRAMPLPVIAAVngvaagaganlalacD-IVMAA--------------ENACFLQAFVKIGLLPDSGGTWFLPQ 152
Cdd:PRK05617  90 yRLNALIARYPKPYIALM---------------DgIVMGGgvgisahgshrivtERTKMAMPETGIGFFPDVGGTYFLSR 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 153 ---RIGvarsMGLAMLGEKLDAKTALAWGLiwgvyhdakilmtevncmADHLAkqPTRALAAIKRAMHAAPTQSLDAQLD 229
Cdd:PRK05617 155 apgALG----TYLALTGARISAADALYAGL------------------ADHFV--PSADLPALLDALISLRWDSGADVVD 210
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
14-218 2.02e-10

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 59.08  E-value: 2.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  14 VATITLNRPDQlNSFTAGMHRELREALDKV-ERQRARALILTGAGRGFCAGQDLSELNFTPGQMTDLGQLIDEQfnpLVR 92
Cdd:PRK05869  18 LATLLLSRPPT-NALTRQVYREIVAAANELgRRDDVAAVILYGGHEIFSAGDDMPELRTLSAQEADTAARVRQQ---AVD 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  93 RLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVARSMGLAMLGEKLDAK 172
Cdd:PRK05869  94 AVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRAAGPSRAKELVFSGRFFDAE 173
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 501404921 173 TALAWGLI------WGVYhDAKIlmtevnCMADHLAKQPTRALAAIKRAMHA 218
Cdd:PRK05869 174 EALALGLIdemvapDDVY-DAAA------AWARRFLDGPPHALAAAKAGISD 218
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
4-179 2.99e-10

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 59.81  E-value: 2.99e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   4 PTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVER-QRARALILTGAGRGFCAGQDLselnftpgQMTDLGQL 82
Cdd:PLN02874  11 EVVLGEEKGRVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKdDSVELIIIKGAGRAFSAGGDL--------KMFYDGRE 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  83 IDEQFNPLVRR-------LRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIG 155
Cdd:PLN02874  83 SDDSCLEVVYRmywlcyhIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILSRLPG 162
                        170       180
                 ....*....|....*....|....*.
gi 501404921 156 varSMG--LAMLGEKLDAKTALAWGL 179
Cdd:PLN02874 163 ---HLGeyLALTGARLNGKEMVACGL 185
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
2-231 4.19e-10

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 58.37  E-value: 4.19e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   2 TSPTILLDWHEHVATITLNRPDQLNSFTAGMHRELREALDKVER-QRARALILTGAGRGFCAGQDLSELNftpgqmtdlg 80
Cdd:PRK08259   1 MSMSVRVERNGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDAdDAASVAVLWGAGGTFCAGADLKAVG---------- 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  81 qliDEQFNPLVR---------RLRaMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGL-LPDsGGTWFL 150
Cdd:PRK08259  71 ---TGRGNRLHPsgdgpmgpsRMR-LSKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVFGVFCRRWGVpLID-GGTVRL 145
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 151 PQRIGVARSMGLAMLGEKLDAKTALAWGLIWGVYHDAKILmTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDL 230
Cdd:PRK08259 146 PRLIGHSRAMDLILTGRPVDADEALAIGLANRVVPKGQAR-AAAEELAAELAAFPQTCLRADRLSALEQWGLPEEAALAN 224

                 .
gi 501404921 231 E 231
Cdd:PRK08259 225 E 225
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
10-260 8.29e-09

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 55.03  E-value: 8.29e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  10 WHEHVAT----ITLNRPDQLNSFTAGMHRELREALDKVERQ-RARALILTG-------AGRGFCAGQDL-----SELNFT 72
Cdd:PRK08321  27 YHRAVDQgtvrIAFDRPEVRNAFRPHTVDELYRALDHARMSpDVGCVLLTGngpspkdGGWAFCSGGDQrirgrDGYQYA 106
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  73 PGQMTD------LGQL-IDEqfnplVRRL-RAMPLPVIAAVNGVAAGAGANLALACDIVMA-AENACFLQAFVKIGLLpD 143
Cdd:PRK08321 107 EGDEADtvdparAGRLhILE-----VQRLiRFMPKVVIAVVPGWAAGGGHSLHVVCDLTLAsREHARFKQTDADVGSF-D 180
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 144 SG-GTWFLPQRIGVARSMGLAMLGEKLDAKTALAWGLIWGVYHDAKILMTEVNCMADHLAKQPTrALAAIKRAMHaAPTQ 222
Cdd:PRK08321 181 GGyGSAYLARQVGQKFAREIFFLGRTYSAEEAHDMGAVNAVVPHAELETEALEWAREINGKSPT-AMRMLKYAFN-LTDD 258
                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 501404921 223 SLDAQLDLERDLQReLGNSRDYA-EGVDAFLNKRVAHFT 260
Cdd:PRK08321 259 GLVGQQLFAGEATR-LAYMTDEAqEGRDAFLEKRDPDWS 296
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
13-257 1.46e-08

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 53.82  E-value: 1.46e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  13 HVATITLNRPdQLNSFTAGMHRELREALDKVER-QRARALILTGAGRGFCAGQDLSELNFTPGQmtdlGQLID------E 85
Cdd:PRK07938  11 GIAEVTVDYP-PVNALPSAGWFALADAITAAGAdPDTRVVVLRAEGRGFNAGVDIKELQATPGF----TALIDanrgcfA 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  86 QFNPLVRrlraMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLpdsGGTWFLPQRIGVARSMGLAML 165
Cdd:PRK07938  86 AFRAVYE----CAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPEVDRGAL---GAATHLQRLVPQHLMRALFFT 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 166 GEKLDAKTALAWGLIWGVYHDAKiLMTEVNCMADHLAKQPTRALAAIKRAMHAAPTQSLDAQLDLERDLQRELGNSRDYA 245
Cdd:PRK07938 159 AATITAAELHHFGSVEEVVPRDQ-LDEAALEVARKIAAKDTRVIRAAKEALNGIDPQDVERSYRWEQGFTFELNLAGVSD 237
                        250
                 ....*....|..
gi 501404921 246 EGVDAFLNKRVA 257
Cdd:PRK07938 238 EHRDAFVEKRKA 249
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
12-180 1.92e-07

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 51.82  E-value: 1.92e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  12 EHVATITLNRPDQ-LNSFTAGMHRELREALDKVERQRA-RALILT-GAGRGFCAGQDLSELNF--TPGQMTDLGQLIDEQ 86
Cdd:PRK11154  14 DNIAVITIDVPGEkMNTLKAEFAEQVRAILKQLREDKElKGVVFIsGKPDNFIAGADINMLAAckTAQEAEALARQGQQL 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  87 FNplvrRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENA--CFLQAFVKIGLLPDSGGTWFLPQRIGVARSMGLAM 164
Cdd:PRK11154  94 FA----EIEALPIPVVAAIHGACLGGGLELALACHYRVCTDDPktVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALDMIL 169
                        170
                 ....*....|....*.
gi 501404921 165 LGEKLDAKTALAWGLI 180
Cdd:PRK11154 170 TGKQLRAKQALKLGLV 185
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
6-179 6.60e-07

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 49.72  E-value: 6.60e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   6 ILLDWHEHVATITLNRPDQLNSFTAGM-HRELREALDKVERQRARALILTGAGRGFCAGQDLSEL--NFTPGQMTDLGQL 82
Cdd:PLN02988  11 VLVEEKSSVRILTLNRPKQLNALSFHMiSRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVvrDIEQGNWRLGANF 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  83 IDEQF--NPLVRRLRAMPLPVIAAVNGVAAGAGANLALacdIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIG-VARS 159
Cdd:PLN02988  91 FSDEYmlNYVMATYSKAQVSILNGIVMGGGAGVSVHGR---FRIATENTVFAMPETALGLFPDVGASYFLSRLPGfFGEY 167
                        170       180
                 ....*....|....*....|
gi 501404921 160 MGLAmlGEKLDAKTALAWGL 179
Cdd:PLN02988 168 VGLT--GARLDGAEMLACGL 185
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
2-180 1.72e-06

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 48.68  E-value: 1.72e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921    2 TSPTILLDWHEH------VATITLNRPD-QLNSFTAGMHRELREALDKVERQRA--RALILTGAGRGFCAGQDLSELNF- 71
Cdd:TIGR02441   5 TSAALMARTHRHyevkgdVAVVKIDSPNsKVNTLSKELFAEFKEVMNELWTNEAikSAVLISGKPGSFVAGADIQMIAAc 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   72 -TPGQMTDLGQLIDEQFNplvrRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAF--VKIGLLPDSGGTW 148
Cdd:TIGR02441  85 kTAQEVTQLSQEGQEMFE----RIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKTLLGLpeVMLGLLPGAGGTQ 160
                         170       180       190
                  ....*....|....*....|....*....|..
gi 501404921  149 FLPQRIGVARSMGLAMLGEKLDAKTALAWGLI 180
Cdd:TIGR02441 161 RLPKLTGVPAALDMMLTGKKIRADRAKKMGIV 192
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
19-179 9.45e-06

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 46.13  E-value: 9.45e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  19 LNRPDQLNSFTAGMHRELREALDKVERQRARALILT-GAGRGFCAGQDLSELNFTPGQ-MTDLGQLIDEQFNPLVRRLRA 96
Cdd:PLN02851  57 LNRPSSLNALTIPMVARLKRLYESWEENPDIGFVLMkGSGRAFCSGADVVSLYHLINEgNVEECKLFFENLYKFVYLQGT 136
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  97 MPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQRIGVarsMG--LAMLGEKLDAKTA 174
Cdd:PLN02851 137 YLKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQMGFHPDAGASYYLSRLPGY---LGeyLALTGQKLNGVEM 213

                 ....*
gi 501404921 175 LAWGL 179
Cdd:PLN02851 214 IACGL 218
PRK06213 PRK06213
crotonase/enoyl-CoA hydratase family protein;
14-102 1.03e-05

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235744  Cd Length: 229  Bit Score: 45.35  E-value: 1.03e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  14 VATITLNRpDQLNSFTAGMHRELREALDKVERQRArALILTGAGRGFCAGQDLSElnFTPGQMTDLGQLidEQFNPLVRR 93
Cdd:PRK06213  13 VATITLDD-GKVNALSPAMIDALNAALDQAEDDRA-VVVITGQPGIFSGGFDLKV--MTSGAQAAIALL--TAGSTLARR 86

                 ....*....
gi 501404921  94 LRAMPLPVI 102
Cdd:PRK06213  87 LLSHPKPVI 95
PLN02267 PLN02267
enoyl-CoA hydratase/isomerase family protein
36-203 1.24e-05

enoyl-CoA hydratase/isomerase family protein


Pssm-ID: 215151  Cd Length: 239  Bit Score: 45.09  E-value: 1.24e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  36 LREALDKVERQRAR--ALILTGAGRGFCAGQDLSELNFTPGQMTDLGQLiDEQFNPLVRRLRAMPLPVIAAVNGVAAGAG 113
Cdd:PLN02267  31 IRSALRQVKSQATPgsVLITTAEGKFFSNGFDLAWAQAAGSAPSRLHLM-VAKLRPLVADLISLPMPTIAAVTGHASAAG 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921 114 ANLALACDIVMAAENACFL-QAFVKIGL-LPDsggtWF---LPQRIGVARSMGLAML-GEKLDAKTALAWGLIWGVYHDA 187
Cdd:PLN02267 110 FILALSHDYVLMRKDRGVLyMSEVDIGLpLPD----YFmalLRAKIGSPAARRDVLLrAAKLTAEEAVEMGIVDSAHDSA 185
                        170
                 ....*....|....*.
gi 501404921 188 KILMTEVNCMADHLAK 203
Cdd:PLN02267 186 EETVEAAVRLGEELAA 201
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
3-183 1.48e-05

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 46.01  E-value: 1.48e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   3 SPTILLDWHE-HVATITLNRPDQLNSFTAGMHRELREALDKVERQR-ARALILTGAGRGFCAGQDLSELnftpgqmTDLG 80
Cdd:PRK11730   5 GKTLQVDWLEdGIAELVFDAPGSVNKLDRATLASLGEALDALEAQSdLKGLLLTSAKDAFIVGADITEF-------LSLF 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  81 QLIDEQF-------NPLVRRLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTWFLPQR 153
Cdd:PRK11730  78 AAPEEELsqwlhfaNSIFNRLEDLPVPTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRL 157
                        170       180       190
                 ....*....|....*....|....*....|
gi 501404921 154 IGVARSMGLAMLGEKLDAKTALAWGLIWGV 183
Cdd:PRK11730 158 IGADNALEWIAAGKDVRAEDALKVGAVDAV 187
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
1-214 1.01e-04

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 42.56  E-value: 1.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921   1 MTSPTILLDWH-EHVATITLNRpDQLNSFTAGMHRELREALDKVERQRA-RALILTGAGRG--FCAGQDLSELNFTPGQM 76
Cdd:PLN03214   8 GATPGVRVDRRpGGIAVVWLAK-EPVNSMTLAMWRSLDDALTALENDPTvRGVVFASGLRRdvFTAGNDIAELYAPKTSA 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  77 TDLGQLIDEQFNPLVRRLRAmPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGL-LPDSGGTWFLPQRIG 155
Cdd:PLN03214  87 ARYAEFWLTQTTFLVRLLRS-RLATVCAIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEVALGIpVPKFWARLFMGRVID 165
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 501404921 156 VARSMGLAMLGEKLDAKTALAWGLIWGVYHDAKiLMTEVNCMADHLAKQPTRALAAIKR 214
Cdd:PLN03214 166 RKVAESLLLRGRLVRPAEAKQLGLIDEVVPAAA-LMEAAASAMERALKLPSAARAATKA 223
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
16-179 3.24e-03

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 38.51  E-value: 3.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  16 TITLNRPDQLNSFTAGMHRELREALDKVERQRARALILT-GAGRGFCAGQDLSELNF--TPGQMTDLGQLIDEQFNpLVR 92
Cdd:PLN02157  49 TAILNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFVMMkGSGRAFCAGGDIVSLYHlrKRGSPDAIREFFSSLYS-FIY 127
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501404921  93 RLRAMPLPVIAAVNGVAAGAGANLALACDIVMAAENACFLQAFVKIGLLPDSGGTW---FLPQRIGVArsmgLAMLGEKL 169
Cdd:PLN02157 128 LLGTYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFnlsHLPGRLGEY----LGLTGLKL 203
                        170
                 ....*....|
gi 501404921 170 DAKTALAWGL 179
Cdd:PLN02157 204 SGAEMLACGL 213
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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