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Conserved domains on  [gi|501259396|ref|WP_012302414|]
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AAA family ATPase [Candidatus Desulforudis audaxviator]

Protein Classification

NadR3 family protein( domain architecture ID 10007007)

NadR3 family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NadR3 COG3172
Nicotinamide riboside kinase [Coenzyme transport and metabolism]; Nicotinamide riboside kinase ...
 1-185 2.26e-29

Nicotinamide riboside kinase [Coenzyme transport and metabolism]; Nicotinamide riboside kinase is part of the Pathway/BioSystem: NAD biosynthesis


:

Pssm-ID: 442405 [Multi-domain]  Cd Length: 178  Bit Score: 107.60  E-value: 2.26e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501259396   1 MRIGLSGAQGVGKTTLAGALARETGLPLVEEQARvvarelgldHLRKLKGRPqLSRSFQWKCLKAQIRAEDELGR----- 75
Cdd:COG3172    9 KKIVLLGAESTGKTTLARALAAHYNTPWVPEYGR---------EYLEEKGRA-LTYDDLLAIARGQLALEDAAAKrankl 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501259396  76 FIADRTVIDNAAyWLKWRSGRSTsranvDYYRECERHaQTYDLMLYVPPEIPLVSNGFRTVNtDYQAEMDWLIRTVLRGL 155
Cdd:COG3172   79 LFCDTDALTTKV-YSELYFGKCP-----PWLEALAAQ-RRYDLYLLLDPDIPWVADGLRDGP-EVREEFQQLLREELEER 150

                        170       180       190
                 ....*....|....*....|....*....|
gi 501259396 156 vpPGKIFTLRGGLEERLSLALGRIRELEKR 185
Cdd:COG3172  151 --GIPYVVISGDYEERLEQALAAIDELLAK 178
 
Name Accession Description Interval E-value
NadR3 COG3172
Nicotinamide riboside kinase [Coenzyme transport and metabolism]; Nicotinamide riboside kinase ...
 1-185 2.26e-29

Nicotinamide riboside kinase [Coenzyme transport and metabolism]; Nicotinamide riboside kinase is part of the Pathway/BioSystem: NAD biosynthesis


Pssm-ID: 442405 [Multi-domain]  Cd Length: 178  Bit Score: 107.60  E-value: 2.26e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501259396   1 MRIGLSGAQGVGKTTLAGALARETGLPLVEEQARvvarelgldHLRKLKGRPqLSRSFQWKCLKAQIRAEDELGR----- 75
Cdd:COG3172    9 KKIVLLGAESTGKTTLARALAAHYNTPWVPEYGR---------EYLEEKGRA-LTYDDLLAIARGQLALEDAAAKrankl 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501259396  76 FIADRTVIDNAAyWLKWRSGRSTsranvDYYRECERHaQTYDLMLYVPPEIPLVSNGFRTVNtDYQAEMDWLIRTVLRGL 155
Cdd:COG3172   79 LFCDTDALTTKV-YSELYFGKCP-----PWLEALAAQ-RRYDLYLLLDPDIPWVADGLRDGP-EVREEFQQLLREELEER 150

                        170       180       190
                 ....*....|....*....|....*....|
gi 501259396 156 vpPGKIFTLRGGLEERLSLALGRIRELEKR 185
Cdd:COG3172  151 --GIPYVVISGDYEERLEQALAAIDELLAK 178
AAA_28 pfam13521
AAA domain;
2-171 1.06e-16

AAA domain;


Pssm-ID: 433278 [Multi-domain]  Cd Length: 164  Bit Score: 74.22  E-value: 1.06e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501259396    2 RIGLSGAQGVGKTTLAGALARETGLPLVEEQARVVARELGLDHLRKLKGRPQLSRsFQWKCLKAQIRAEDEL---GRFIA 78
Cdd:pfam13521   1 RIVITGGPSTGKTTLAEALAARFGYPVVPEAAREILEELGADGGDALPWVEDLLA-FARGVLEAQLEDEAAAaanDLLFF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501259396   79 DRTVIDNAAYWLkwrsgrstsRANVDYYRECERHA--QTYDLMLYVPPEIPLVSNGFRTVNTDYQAEMDWLIRTVLRGL- 155
Cdd:pfam13521  80 DRGPLDTLAYSR---------AYGGPCPPELEAAAraSRYDLVFLLPPDPEIVQDGERREDPEERERFHERLREALRELg 150

                         170
                  ....*....|....*.
gi 501259396  156 VPpgKIFTLRGGLEER 171
Cdd:pfam13521 151 IP--VIIVPRGSVEER 164
PRK04182 PRK04182
cytidylate kinase; Provisional
 1-43 3.15e-05

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 42.87  E-value: 3.15e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 501259396   1 MRIGLSGAQGVGKTTLAGALARETGLPLVE--EQARVVARELGLD 43
Cdd:PRK04182   1 MIITISGPPGSGKTTVARLLAEKLGLKHVSagEIFRELAKERGMS 45
CooC1 cd02034
accessory protein CooC1; The accessory protein CooC1, a nickel-binding ATPase, participates in ...
 1-37 8.21e-03

accessory protein CooC1; The accessory protein CooC1, a nickel-binding ATPase, participates in the incorporation of nickel into the complex active site ([Ni-4Fe-4S]) cluster of Ni,Fe-dependent carbon monoxide dehydrogenase (CODH). CODH from Rhodospirillum rubrum catalyzes the reversible oxidation of CO to CO2. CODH contains a nickel-iron-sulfur cluster (C-center) and an iron-sulfur cluster (B-center). CO oxidation occurs at the C-center. Three accessory proteins encoded by cooCTJ genes are involved in nickel incorporation into a nickel site. CooC functions as a nickel insertase that mobilizes nickel to apoCODH using energy released from ATP hydrolysis. CooC is a homodimer and has NTPase activities. Mutation at the P-loop abolishs its function.


Pssm-ID: 349754 [Multi-domain]  Cd Length: 249  Bit Score: 36.13  E-value: 8.21e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 501259396   1 MRIGLSGAQGVGKTTLAGALAREtglpLVEEQARVVA 37
Cdd:cd02034    1 MKIAVAGKGGVGKTTIAALLIRY----LAKKGGKVLA 33
 
Name Accession Description Interval E-value
NadR3 COG3172
Nicotinamide riboside kinase [Coenzyme transport and metabolism]; Nicotinamide riboside kinase ...
 1-185 2.26e-29

Nicotinamide riboside kinase [Coenzyme transport and metabolism]; Nicotinamide riboside kinase is part of the Pathway/BioSystem: NAD biosynthesis


Pssm-ID: 442405 [Multi-domain]  Cd Length: 178  Bit Score: 107.60  E-value: 2.26e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501259396   1 MRIGLSGAQGVGKTTLAGALARETGLPLVEEQARvvarelgldHLRKLKGRPqLSRSFQWKCLKAQIRAEDELGR----- 75
Cdd:COG3172    9 KKIVLLGAESTGKTTLARALAAHYNTPWVPEYGR---------EYLEEKGRA-LTYDDLLAIARGQLALEDAAAKrankl 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501259396  76 FIADRTVIDNAAyWLKWRSGRSTsranvDYYRECERHaQTYDLMLYVPPEIPLVSNGFRTVNtDYQAEMDWLIRTVLRGL 155
Cdd:COG3172   79 LFCDTDALTTKV-YSELYFGKCP-----PWLEALAAQ-RRYDLYLLLDPDIPWVADGLRDGP-EVREEFQQLLREELEER 150

                        170       180       190
                 ....*....|....*....|....*....|
gi 501259396 156 vpPGKIFTLRGGLEERLSLALGRIRELEKR 185
Cdd:COG3172  151 --GIPYVVISGDYEERLEQALAAIDELLAK 178
AAA_28 pfam13521
AAA domain;
2-171 1.06e-16

AAA domain;


Pssm-ID: 433278 [Multi-domain]  Cd Length: 164  Bit Score: 74.22  E-value: 1.06e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501259396    2 RIGLSGAQGVGKTTLAGALARETGLPLVEEQARVVARELGLDHLRKLKGRPQLSRsFQWKCLKAQIRAEDEL---GRFIA 78
Cdd:pfam13521   1 RIVITGGPSTGKTTLAEALAARFGYPVVPEAAREILEELGADGGDALPWVEDLLA-FARGVLEAQLEDEAAAaanDLLFF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501259396   79 DRTVIDNAAYWLkwrsgrstsRANVDYYRECERHA--QTYDLMLYVPPEIPLVSNGFRTVNTDYQAEMDWLIRTVLRGL- 155
Cdd:pfam13521  80 DRGPLDTLAYSR---------AYGGPCPPELEAAAraSRYDLVFLLPPDPEIVQDGERREDPEERERFHERLREALRELg 150

                         170
                  ....*....|....*.
gi 501259396  156 VPpgKIFTLRGGLEER 171
Cdd:pfam13521 151 IP--VIIVPRGSVEER 164
PRK04182 PRK04182
cytidylate kinase; Provisional
 1-43 3.15e-05

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 42.87  E-value: 3.15e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 501259396   1 MRIGLSGAQGVGKTTLAGALARETGLPLVE--EQARVVARELGLD 43
Cdd:PRK04182   1 MIITISGPPGSGKTTVARLLAEKLGLKHVSagEIFRELAKERGMS 45
Fap7 COG1936
Broad-specificity NMP kinase [Nucleotide transport and metabolism];
1-30 4.08e-05

Broad-specificity NMP kinase [Nucleotide transport and metabolism];


Pssm-ID: 441539 [Multi-domain]  Cd Length: 173  Bit Score: 42.50  E-value: 4.08e-05
                         10        20        30
                 ....*....|....*....|....*....|
gi 501259396   1 MRIGLSGAQGVGKTTLAGALARETGLPLVE 30
Cdd:COG1936    1 MRIAITGTPGTGKTTVAKLLAERLGLEVIH 30
PRK04195 PRK04195
replication factor C large subunit; Provisional
 5-30 4.98e-05

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 43.37  E-value: 4.98e-05
                         10        20
                 ....*....|....*....|....*.
gi 501259396   5 LSGAQGVGKTTLAGALARETGLPLVE 30
Cdd:PRK04195  44 LYGPPGVGKTSLAHALANDYGWEVIE 69
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
 5-30 3.05e-04

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 39.50  E-value: 3.05e-04
                          10        20
                  ....*....|....*....|....*.
gi 501259396    5 LSGAQGVGKTTLAGALARETGLPLVE 30
Cdd:pfam00004   3 LYGPPGTGKTTLAKAVAKELGAPFIE 28
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
 5-30 3.85e-04

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 40.66  E-value: 3.85e-04
                         10        20
                 ....*....|....*....|....*.
gi 501259396   5 LSGAQGVGKTTLAGALARETGLPLVE 30
Cdd:COG0464  196 LYGPPGTGKTLLARALAGELGLPLIE 221
COG1223 COG1223
Predicted ATPase, AAA+ superfamily [General function prediction only];
2-30 4.41e-04

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440836 [Multi-domain]  Cd Length: 246  Bit Score: 39.87  E-value: 4.41e-04
                         10        20
                 ....*....|....*....|....*....
gi 501259396   2 RIGLSGAQGVGKTTLAGALARETGLPLVE 30
Cdd:COG1223   37 KILFYGPPGTGKTMLAEALAGELKLPLLT 65
CooC COG3640
CO dehydrogenase nickel-insertion accessory protein CooC1 [Posttranslational modification, ...
 1-37 5.66e-04

CO dehydrogenase nickel-insertion accessory protein CooC1 [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442857 [Multi-domain]  Cd Length: 249  Bit Score: 39.76  E-value: 5.66e-04
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 501259396   1 MRIGLSGAQGVGKTTLAGALAREtglpLVEEQARVVA 37
Cdd:COG3640    1 MKIAVAGKGGVGKTTLSALLARY----LAEKGKPVLA 33
AAA_17 pfam13207
AAA domain;
6-92 7.22e-04

AAA domain;


Pssm-ID: 463810 [Multi-domain]  Cd Length: 136  Bit Score: 38.37  E-value: 7.22e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501259396    6 SGAQGVGKTTLAGALARETGLPLVE--EQARVVARELGL----DHLRKLKGRPQLSRsfqWKCLKAQIRAEDELGRFIAD 79
Cdd:pfam13207   1 TGVPGSGKTTQLKKLAEKLGFPHISagDLLREEAKERGLvedrDEMRKLPLEPQKEL---QKLAAERIAEEAGEGGVIVD 77

                          90
                  ....*....|....*
gi 501259396   80 --RTVIDNAAYWLKW 92
Cdd:pfam13207  78 ghPRIKTPAGYLPGL 92
AAA_18 pfam13238
AAA domain;
3-84 1.57e-03

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 37.41  E-value: 1.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501259396    3 IGLSGAQGVGKTTLAGALARETGLPLVeeqARVVARELGLdHLRKLKGRPQLSRSFQWKCLKAQIRAEDELGRFIADRTV 82
Cdd:pfam13238   1 ILITGTPGVGKTTLAKELSKRLGFGDN---VRDLALENGL-VLGDDPETRESKRLDEDKLDRLLDLLEENAALEEGGNLI 76


                  ..
gi 501259396   83 ID 84
Cdd:pfam13238  77 ID 78
fliI PRK07721
flagellar protein export ATPase FliI;
2-47 3.16e-03

flagellar protein export ATPase FliI;


Pssm-ID: 181092 [Multi-domain]  Cd Length: 438  Bit Score: 37.78  E-value: 3.16e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 501259396   2 RIGLSGAQGVGKTTLAGALARETG-----LPLVEEQARVV----ARELGLDHLRK 47
Cdd:PRK07721 160 RVGIFAGSGVGKSTLMGMIARNTSadlnvIALIGERGREVrefiERDLGPEGLKR 214
Dck COG1428
Deoxyadenosine/deoxycytidine kinase [Nucleotide transport and metabolism];
1-32 5.12e-03

Deoxyadenosine/deoxycytidine kinase [Nucleotide transport and metabolism];


Pssm-ID: 441037 [Multi-domain]  Cd Length: 205  Bit Score: 36.69  E-value: 5.12e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 501259396   1 MRIGLSGAQGVGKTTLAGALARETGLPLVEEQ 32
Cdd:COG1428    4 RYIAVEGNIGAGKTTLARLLAEHLGAELLLEP 35
Pgk2 COG2074
2-phosphoglycerate kinase/Mevalonate-3-phosphate 5-kinase [Carbohydrate transport and ...
 3-29 5.41e-03

2-phosphoglycerate kinase/Mevalonate-3-phosphate 5-kinase [Carbohydrate transport and metabolism, Lipid transport and metabolism];


Pssm-ID: 441677  Cd Length: 207  Bit Score: 36.47  E-value: 5.41e-03
                         10        20
                 ....*....|....*....|....*..
gi 501259396   3 IGlsGAQGVGKTTLAGALARETGLPLV 29
Cdd:COG2074   11 IG--GASGVGKSTIAAELARRLGIPRV 35
CooC1 cd02034
accessory protein CooC1; The accessory protein CooC1, a nickel-binding ATPase, participates in ...
 1-37 8.21e-03

accessory protein CooC1; The accessory protein CooC1, a nickel-binding ATPase, participates in the incorporation of nickel into the complex active site ([Ni-4Fe-4S]) cluster of Ni,Fe-dependent carbon monoxide dehydrogenase (CODH). CODH from Rhodospirillum rubrum catalyzes the reversible oxidation of CO to CO2. CODH contains a nickel-iron-sulfur cluster (C-center) and an iron-sulfur cluster (B-center). CO oxidation occurs at the C-center. Three accessory proteins encoded by cooCTJ genes are involved in nickel incorporation into a nickel site. CooC functions as a nickel insertase that mobilizes nickel to apoCODH using energy released from ATP hydrolysis. CooC is a homodimer and has NTPase activities. Mutation at the P-loop abolishs its function.


Pssm-ID: 349754 [Multi-domain]  Cd Length: 249  Bit Score: 36.13  E-value: 8.21e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 501259396   1 MRIGLSGAQGVGKTTLAGALAREtglpLVEEQARVVA 37
Cdd:cd02034    1 MKIAVAGKGGVGKTTIAALLIRY----LAKKGGKVLA 33
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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