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Conserved domains on  [gi|501083135|ref|WP_012133673|]
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MULTISPECIES: putative lateral flagellar export/assembly protein LafU [Citrobacter]

Protein Classification

MotB family protein( domain architecture ID 11482413)

MotB family protein similar to Escherichia coli putative lateral flagellar export/assembly protein LafU that could be the product of a pseudogene

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK06778 PRK06778
hypothetical protein; Validated
 9-315 3.24e-175

hypothetical protein; Validated


:

Pssm-ID: 235860 [Multi-domain]  Cd Length: 289  Bit Score: 486.36  E-value: 3.24e-175
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135   9 TTIIKRSSRKSHDEFHGGAWKVAFADFTLAMMALFMVLWIMGAVTEEERKEIVSMLNGESVFegnsltpitqkegQGGQL 88
Cdd:PRK06778   3 TTIIKRANRKKHHVRHSGAWKVAFADFTLAMMALFMVLWIVNSVSKSERESIIAALHGQSIF-------------NGGGL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  89 SLIDSRHPKTPKPSKTAESSKPLTDAEKQVaqqakqTESLDDVNARSRNEIEDLARIIMKITSTYDAQANLKMEIVPQGL 168
Cdd:PRK06778  70 SPLNKISPSHPPKPATVAVPEETEKKARDV------NEKTALLKKKSATELGELATSINTIARDAHMEANLEMEIVPQGL 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 169 RILVSDDQKREMFQRSSAILTPFFKRLLTEFAPELNKIDNKIIITGHTDATRFRDQVlYNNWNLSGERAMQARAVLTTGG 248
Cdd:PRK06778 144 RVLIKDDQNRNMFERGSAQIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKNNI-YNNWNLSGDRALSARRVLEEAG 222

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 501083135 249 LDQSKILQVSGMADQMLLDPQHPLSSANRRIEIMVLTHSASDSLYQFFGQHGEKVIKPLTDKLTKNH 315
Cdd:PRK06778 223 MPEDKVMQVSAMADQMLLDAKNPQSAGNRRIEIMVLTKSASDTLYQYFGQHGDKVVQPLVQKLDKQQ 289
 
Name Accession Description Interval E-value
PRK06778 PRK06778
hypothetical protein; Validated
 9-315 3.24e-175

hypothetical protein; Validated


Pssm-ID: 235860 [Multi-domain]  Cd Length: 289  Bit Score: 486.36  E-value: 3.24e-175
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135   9 TTIIKRSSRKSHDEFHGGAWKVAFADFTLAMMALFMVLWIMGAVTEEERKEIVSMLNGESVFegnsltpitqkegQGGQL 88
Cdd:PRK06778   3 TTIIKRANRKKHHVRHSGAWKVAFADFTLAMMALFMVLWIVNSVSKSERESIIAALHGQSIF-------------NGGGL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  89 SLIDSRHPKTPKPSKTAESSKPLTDAEKQVaqqakqTESLDDVNARSRNEIEDLARIIMKITSTYDAQANLKMEIVPQGL 168
Cdd:PRK06778  70 SPLNKISPSHPPKPATVAVPEETEKKARDV------NEKTALLKKKSATELGELATSINTIARDAHMEANLEMEIVPQGL 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 169 RILVSDDQKREMFQRSSAILTPFFKRLLTEFAPELNKIDNKIIITGHTDATRFRDQVlYNNWNLSGERAMQARAVLTTGG 248
Cdd:PRK06778 144 RVLIKDDQNRNMFERGSAQIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKNNI-YNNWNLSGDRALSARRVLEEAG 222

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 501083135 249 LDQSKILQVSGMADQMLLDPQHPLSSANRRIEIMVLTHSASDSLYQFFGQHGEKVIKPLTDKLTKNH 315
Cdd:PRK06778 223 MPEDKVMQVSAMADQMLLDAKNPQSAGNRRIEIMVLTKSASDTLYQYFGQHGDKVVQPLVQKLDKQQ 289
MotB COG1360
Flagellar motor protein MotB [Cell motility];
20-291 1.42e-41

Flagellar motor protein MotB [Cell motility];


Pssm-ID: 440971 [Multi-domain]  Cd Length: 174  Bit Score: 141.91  E-value: 1.42e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  20 HDEFHGGAWKVAFADFTLAMMALFMVLWIMGAVTEEErkeivsmlngesvfegnsltpitqkegqggqlslidsrhpktp 99
Cdd:COG1360    2 EEGHHGGAWLVTYADLMTLLLAFFVLLWALSSALEEN------------------------------------------- 38

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 100 kpsktaesskpltdaekqvaqqakqteslddvnarsrneiedlariimkitstyDAQANLKMEIVPQGLRILVSDdqkRE 179
Cdd:COG1360   39 ------------------------------------------------------LLSGQVEVRITEEGLVIEIQD---RV 61

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 180 MFQRSSAILTPFFKRLLTEFAPELNKIDNKIIITGHTDATRFRDQVLYNNWNLSGERAMQARAVLTTGGLDQSKiLQVSG 259
Cdd:COG1360   62 LFDSGSAELTPEGRELLDKIAAVLAEVPNRIRVEGHTDNVPISTARFPSNWELSAARAAAVVRYLIEGGVPPER-LSAVG 140

                        250       260       270
                 ....*....|....*....|....*....|....
gi 501083135 260 MADQMLLDPQH--PLSSANRRIEIMVLTHSASDS 291
Cdd:COG1360  141 YGDTRPLAPNDtpEGRARNRRVEIVILRRAAEEA 174
OmpA_C-like cd07185
Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; ...
 181-283 2.69e-17

Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.


Pssm-ID: 143586 [Multi-domain]  Cd Length: 106  Bit Score: 76.05  E-value: 2.69e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 181 FQRSSAILTPFFKRLLTEFAPELNKIDN-KIIITGHTDAT-RFRDqvlynNWNLSGERAMQARAVLTTGGLDQSKIlQVS 258
Cdd:cd07185    6 FDFGSAELTPEAKPLLDKLAEVLKKNPDaKIRIEGHTDSRgSDAY-----NQELSERRAEAVADYLVSKGVDASRI-TAV 79

                         90       100
                 ....*....|....*....|....*..
gi 501083135 259 GMADQMLLDPQH--PLSSANRRIEIMV 283
Cdd:cd07185   80 GYGESRPIASNDteEGRAKNRRVEIVI 106
type_VI_ompA TIGR03350
type VI secretion system peptidoglycan-associated domain; The flagellar motor protein MotB, ...
 156-283 6.58e-16

type VI secretion system peptidoglycan-associated domain; The flagellar motor protein MotB, the Gram-negative bacterial outer membrane protein OmpA (with an N-terminal outer membrane beta barrel domain) share a C-terminal peptidoglycan-associating homology region. This model describes a domain found fused to type VI secretion system homologs of the type IV system protein DotU (see model TIGR03349), with OmpA/MotB homology. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274533 [Multi-domain]  Cd Length: 137  Bit Score: 73.10  E-value: 6.58e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  156 QANLKMEIVPQGLRilVSDDQKR--------EMFQRSSAILTPFFKRLLTEFAPELNKIDNKIIITGHTDATRFRDQVLY 227
Cdd:TIGR03350   3 RALLAPEIAAGLLT--VDEDGDRsvvrlrgdELFASGSAEVRAEFEPLLLRIAKALAAVPGRITVVGHTDNVPIRTARFP 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 501083135  228 NNWNLSGERAMQARAVLTTGGLDQSKIlQVSGMAD-QMLLDPQHPLS-SANRRIEIMV 283
Cdd:TIGR03350  81 SNWHLSEARAKAVADVLAQAGGPAGRV-RAEGRGDsEPIASNATAAGrARNRRVEIDV 137
MotB_plug pfam13677
Membrane MotB of proton-channel complex MotA/MotB; This is the MotB member of the E.coli MotA ...
 13-66 7.90e-15

Membrane MotB of proton-channel complex MotA/MotB; This is the MotB member of the E.coli MotA/MotB proton-channel complex that forms the stator of the bacterial membrane flagellar motor. Key residues act as a plug to prevent premature proton flow. The plug is in the periplasm just C-terminal to the MotB TM, consisting of an amphipathic alpha helix flanked by Pro-52 and Pro-65, eg in Swiss:D3V2T1. In addition to the Pro residues, Ile-58, Tyr-61, and Phe 62 are also essential for plug function.


Pssm-ID: 463955 [Multi-domain]  Cd Length: 57  Bit Score: 67.55  E-value: 7.90e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 501083135   13 KRSSRKSHDEFHGGAWKVAFADFTLAMMALFMVLWIMGAVTEEERKEIVSMLNG 66
Cdd:pfam13677   2 KKKKEPEHEGGHGERWLVTYADLMTLLLAFFVLLYSMSSVDEKKFQQIAESFQD 55
 
Name Accession Description Interval E-value
PRK06778 PRK06778
hypothetical protein; Validated
 9-315 3.24e-175

hypothetical protein; Validated


Pssm-ID: 235860 [Multi-domain]  Cd Length: 289  Bit Score: 486.36  E-value: 3.24e-175
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135   9 TTIIKRSSRKSHDEFHGGAWKVAFADFTLAMMALFMVLWIMGAVTEEERKEIVSMLNGESVFegnsltpitqkegQGGQL 88
Cdd:PRK06778   3 TTIIKRANRKKHHVRHSGAWKVAFADFTLAMMALFMVLWIVNSVSKSERESIIAALHGQSIF-------------NGGGL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  89 SLIDSRHPKTPKPSKTAESSKPLTDAEKQVaqqakqTESLDDVNARSRNEIEDLARIIMKITSTYDAQANLKMEIVPQGL 168
Cdd:PRK06778  70 SPLNKISPSHPPKPATVAVPEETEKKARDV------NEKTALLKKKSATELGELATSINTIARDAHMEANLEMEIVPQGL 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 169 RILVSDDQKREMFQRSSAILTPFFKRLLTEFAPELNKIDNKIIITGHTDATRFRDQVlYNNWNLSGERAMQARAVLTTGG 248
Cdd:PRK06778 144 RVLIKDDQNRNMFERGSAQIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKNNI-YNNWNLSGDRALSARRVLEEAG 222

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 501083135 249 LDQSKILQVSGMADQMLLDPQHPLSSANRRIEIMVLTHSASDSLYQFFGQHGEKVIKPLTDKLTKNH 315
Cdd:PRK06778 223 MPEDKVMQVSAMADQMLLDAKNPQSAGNRRIEIMVLTKSASDTLYQYFGQHGDKVVQPLVQKLDKQQ 289
motB PRK09041
motility protein MotB;
1-292 4.34e-65

motility protein MotB;


Pssm-ID: 236365 [Multi-domain]  Cd Length: 317  Bit Score: 207.49  E-value: 4.34e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135   1 MRNRSKeHTTIIKRSSRKSHDEfHGGAWKVAFADFTLAMMALFMVLWIMGAVTEEERKEI---------VSMLNGESvfE 71
Cdd:PRK09041   1 MKKENH-PPIVVKRVKKKGHGH-HGGSWKIAYADFMTAMMAFFLVMWLLSSSTPEQLIGIaeyfrtplkVALTGGDR--S 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  72 GNSLTPItqkegQGGqlslidsrhpktpkpsktaesSKPLTDAEKQVAQQAKQTESLDdvNARSRNEIEDLARIIMKITS 151
Cdd:PRK09041  77 SDSTSPI-----PGG---------------------GDDITQQDGEVNKQPNIAELAQ--GEKERREQERLEKLKQELDQ 128

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 152 TYDA-------QANLKMEIVPQGLRILVSDDQKREMFQRSSAILTPFFKRLLTEFAPELNKIDNKIIITGHTDATRF-RD 223
Cdd:PRK09041 129 AIESnpklrqfKPQLLIDLTQEGLRIQIVDSQNRPMFATGSAEVEPYMRDILREIAPVLNDVPNRISLSGHTDATPYaNG 208

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 501083135 224 QVLYNNWNLSGERAMQARAVLTTGGLDQSKILQVSGMADQMLLDPQHPLSSANRRIEIMVLTHSASDSL 292
Cdd:PRK09041 209 EKGYSNWELSADRANASRRELVAGGMDEGKVLRVVGLASTMLLDKKDPLNPVNRRISIVVLNKKAEEAI 277
motB PRK12799
flagellar motor protein MotB; Reviewed
 4-292 1.33e-47

flagellar motor protein MotB; Reviewed


Pssm-ID: 183756 [Multi-domain]  Cd Length: 421  Bit Score: 164.89  E-value: 1.33e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135   4 RSKEHTTIIKRSSRKSHDE-FHGGAWKVAFADFTLAMMALFMVLWIMGAVTEEERKEIVSMLNgesvfegnslTPITQKE 82
Cdd:PRK12799   2 KHQNHPVILVKKRKTKHGAaHYGGSWKIAYADFMTAMMAFFLVMWLLAVSSPQELTQIAEYFR----------TPLKVAL 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  83 GQGgqlslidsrhpktpkpSKTAESSKPL----TDAEKQVAQQAKQTESLDdvnarSRNEIEDLARIIMKITSTYDAQAN 158
Cdd:PRK12799  72 TSG----------------DKSSSSTSPIpgggDDPTQQVGEVRKQINSEE-----SRQEIHRLNKLREKLDQLIESDPR 130

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 159 LK-------MEIVPQGLRILVSDDQKREMFQRSSAILTPFFKRLLTEFAPELNKIDNKIIITGHTDATRF-RDQVLYNNW 230
Cdd:PRK12799 131 LKalrphllINMMDEGLRIQIIDSQNRPMFKMGSAQVEPYMRDILRAIAPILNDIPNKLSLSGHTDDLPYaRGERGYSNW 210

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 501083135 231 NLSGERAMQARAVLTTGGLDQSKILQVSGMADQMLLDPQHPLSSANRRIEIMVLTHSASDSL 292
Cdd:PRK12799 211 ELSADRANASRRELLAGGLDEGKILRVVGMASTMRLKEQASDDPVNRRISILVLNKQSQHDI 272
MotB COG1360
Flagellar motor protein MotB [Cell motility];
20-291 1.42e-41

Flagellar motor protein MotB [Cell motility];


Pssm-ID: 440971 [Multi-domain]  Cd Length: 174  Bit Score: 141.91  E-value: 1.42e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  20 HDEFHGGAWKVAFADFTLAMMALFMVLWIMGAVTEEErkeivsmlngesvfegnsltpitqkegqggqlslidsrhpktp 99
Cdd:COG1360    2 EEGHHGGAWLVTYADLMTLLLAFFVLLWALSSALEEN------------------------------------------- 38

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 100 kpsktaesskpltdaekqvaqqakqteslddvnarsrneiedlariimkitstyDAQANLKMEIVPQGLRILVSDdqkRE 179
Cdd:COG1360   39 ------------------------------------------------------LLSGQVEVRITEEGLVIEIQD---RV 61

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 180 MFQRSSAILTPFFKRLLTEFAPELNKIDNKIIITGHTDATRFRDQVLYNNWNLSGERAMQARAVLTTGGLDQSKiLQVSG 259
Cdd:COG1360   62 LFDSGSAELTPEGRELLDKIAAVLAEVPNRIRVEGHTDNVPISTARFPSNWELSAARAAAVVRYLIEGGVPPER-LSAVG 140

                        250       260       270
                 ....*....|....*....|....*....|....
gi 501083135 260 MADQMLLDPQH--PLSSANRRIEIMVLTHSASDS 291
Cdd:COG1360  141 YGDTRPLAPNDtpEGRARNRRVEIVILRRAAEEA 174
motB PRK05996
MotB family protein;
11-283 1.52e-37

MotB family protein;


Pssm-ID: 235665 [Multi-domain]  Cd Length: 423  Bit Score: 138.29  E-value: 1.52e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  11 IIKRSSRKSHDEFHGGAWKVAFADFTLAMMALFMVLWIMGAVTEEERKEIVSMLN------------------------- 65
Cdd:PRK05996  15 IVRRGGDDDHEGHHGGVWKIAYADFMTAMMAFFLVMWLINAANEETKAAVASYFNpikltdrkpsekglkdpvdgaegeq 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  66 --------------GESVFEGNSLTP-----------------------ITQKEGQ----------------------GG 86
Cdd:PRK05996  95 kpgkskfeedqrveGSSAVTGDDTTRtsgdqtnyseadlfrnpyavlaeIAQEVGQqanvsakgdggaaqsgpatgadGG 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  87 Q-----------------------LSLIDSRHPKTPKPSKTAESSKPLTDAE---------------------------- 115
Cdd:PRK05996 175 EayrdpfdpdfwskqvevttagdlLPPGQAREQAQGAKSATAAPATVPQAAPlpqaqpkkaateeeliadakkaatgepa 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 116 KQVAQQAKQTESLDDVNARSRNEIEDLARIIMKITstydAQANLKMEIVP--QGLRILVSDDQKREMFQRSSAILTPFFK 193
Cdd:PRK05996 255 ANAAKAAKPEPMPDDQQKEAEQLQAAIAQAIGGVA----GKLAEGVTVTPveGGLLISLTDQVDYGMFAIGSAVPRAELV 330

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 194 RLLTEFAPELNKIDNKIIITGHTDATRFRDQVlYNNWNLSGERAMQARAVLTTGGLDQSKILQVSGMADQMLLDPQHPLS 273
Cdd:PRK05996 331 LAMEKIGQLLAERPGAVIIRGHTDARPFKSAT-YDNWRLSTARAQSAYYMLVRGGLDEKRIEQVEGFADRRPKLPNDPNA 409

                        410
                 ....*....|
gi 501083135 274 SANRRIEIMV 283
Cdd:PRK05996 410 AANRRIEILI 419
motB PRK08944
flagellar motor protein MotB; Reviewed
 27-291 7.42e-18

flagellar motor protein MotB; Reviewed


Pssm-ID: 236356 [Multi-domain]  Cd Length: 302  Bit Score: 81.98  E-value: 7.42e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  27 AWKVAFADFTLAMMALFMVLWIMGAVTEEERKEIV-SM---------LNGESVFEGNSL------------TPITQKEGQ 84
Cdd:PRK08944  16 AWLATFADLMSLLMCFFVLLLSFSEMDVLKFKQIAgSMkfafgvqnkIEVKDIPKGTSIiaqefrpgrpepTPIEVIMQQ 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  85 GGQLSL--IDSRHPKTPKPSKTAESSKPLTDAEKQVAQQAKQTESLDDvnarsrneIEDLARIImkitstydAQAnLKME 162
Cdd:PRK08944  96 TIDMTQqtLEFQAGESDSAGGTQQQRGKQRGGEASAEVKAEKAAAQEQ--------IEDLVKKL--------AQQ-LEKE 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 163 IVPQGLRILVSDDQK----RE--MFQRSSAILTPFFKRLLTEFAPELNKIDNKIIITGHTDATRFRDQVLYNNWNLSGER 236
Cdd:PRK08944 159 IEDGAIEIESLGQQIiiriREkgSFPSGSAFLQPKFKPVVRKIGELLKDVPGIITVSGHTDNVPISSELYRSNWDLSSAR 238

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 237 AMQ-ARAVLTTGGLDQSKiLQVSGMADQMLLDP----QHplSSANRRIEIMVLTHSASDS 291
Cdd:PRK08944 239 AVAvAHELLKVKGFDPQR-LKVVGMADTQPLVPndtaEN--RARNRRVEIIIEQGKAKES 295
OmpA_C-like cd07185
Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; ...
 181-283 2.69e-17

Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.


Pssm-ID: 143586 [Multi-domain]  Cd Length: 106  Bit Score: 76.05  E-value: 2.69e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 181 FQRSSAILTPFFKRLLTEFAPELNKIDN-KIIITGHTDAT-RFRDqvlynNWNLSGERAMQARAVLTTGGLDQSKIlQVS 258
Cdd:cd07185    6 FDFGSAELTPEAKPLLDKLAEVLKKNPDaKIRIEGHTDSRgSDAY-----NQELSERRAEAVADYLVSKGVDASRI-TAV 79

                         90       100
                 ....*....|....*....|....*..
gi 501083135 259 GMADQMLLDPQH--PLSSANRRIEIMV 283
Cdd:cd07185   80 GYGESRPIASNDteEGRAKNRRVEIVI 106
type_VI_ompA TIGR03350
type VI secretion system peptidoglycan-associated domain; The flagellar motor protein MotB, ...
 156-283 6.58e-16

type VI secretion system peptidoglycan-associated domain; The flagellar motor protein MotB, the Gram-negative bacterial outer membrane protein OmpA (with an N-terminal outer membrane beta barrel domain) share a C-terminal peptidoglycan-associating homology region. This model describes a domain found fused to type VI secretion system homologs of the type IV system protein DotU (see model TIGR03349), with OmpA/MotB homology. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274533 [Multi-domain]  Cd Length: 137  Bit Score: 73.10  E-value: 6.58e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  156 QANLKMEIVPQGLRilVSDDQKR--------EMFQRSSAILTPFFKRLLTEFAPELNKIDNKIIITGHTDATRFRDQVLY 227
Cdd:TIGR03350   3 RALLAPEIAAGLLT--VDEDGDRsvvrlrgdELFASGSAEVRAEFEPLLLRIAKALAAVPGRITVVGHTDNVPIRTARFP 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 501083135  228 NNWNLSGERAMQARAVLTTGGLDQSKIlQVSGMAD-QMLLDPQHPLS-SANRRIEIMV 283
Cdd:TIGR03350  81 SNWHLSEARAKAVADVLAQAGGPAGRV-RAEGRGDsEPIASNATAAGrARNRRVEIDV 137
MotB_plug pfam13677
Membrane MotB of proton-channel complex MotA/MotB; This is the MotB member of the E.coli MotA ...
 13-66 7.90e-15

Membrane MotB of proton-channel complex MotA/MotB; This is the MotB member of the E.coli MotA/MotB proton-channel complex that forms the stator of the bacterial membrane flagellar motor. Key residues act as a plug to prevent premature proton flow. The plug is in the periplasm just C-terminal to the MotB TM, consisting of an amphipathic alpha helix flanked by Pro-52 and Pro-65, eg in Swiss:D3V2T1. In addition to the Pro residues, Ile-58, Tyr-61, and Phe 62 are also essential for plug function.


Pssm-ID: 463955 [Multi-domain]  Cd Length: 57  Bit Score: 67.55  E-value: 7.90e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 501083135   13 KRSSRKSHDEFHGGAWKVAFADFTLAMMALFMVLWIMGAVTEEERKEIVSMLNG 66
Cdd:pfam13677   2 KKKKEPEHEGGHGERWLVTYADLMTLLLAFFVLLYSMSSVDEKKFQQIAESFQD 55
OmpA pfam00691
OmpA family; The Pfam entry also includes MotB and related proteins which are not included in ...
 181-278 4.77e-13

OmpA family; The Pfam entry also includes MotB and related proteins which are not included in the Prosite family.


Pssm-ID: 425825 [Multi-domain]  Cd Length: 95  Bit Score: 63.92  E-value: 4.77e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  181 FQRSSAILTPFFKRLLTEFAPELNKIDNK--IIITGHTDATRFRDQvlynNWNLSGERAMQARAVLTTGGLDQSKIlQVS 258
Cdd:pfam00691   1 FDPGSSQLTPKAKATLDEIADLLKFPELKntITIEGHTDTVGSAAY----NWELSQRRAEAVRRYLVNFGVPPSRI-SVV 75

                          90       100
                  ....*....|....*....|
gi 501083135  259 GMADQMLLDPQHPLSSANRR 278
Cdd:pfam00691  76 GYGATKPITDNKTPEGRARN 95
motB PRK07734
flagellar motor protein MotB; Reviewed
 13-284 1.63e-12

flagellar motor protein MotB; Reviewed


Pssm-ID: 236080 [Multi-domain]  Cd Length: 259  Bit Score: 66.30  E-value: 1.63e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  13 KRSSRKSHDEFHGGAWKVAFADFTLAMMALFMVLWIMGAVTEEERKEIVSMLNgeSVFEGNSltpitqkegqgGQLSLID 92
Cdd:PRK07734   4 RKKKKKKHEEHIDESWLIPYADLLTLLLALFIVLFAMSSIDAAKFKQMAVAFN--SEFAGGT-----------GVKDFLS 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  93 SRHPKTPKpsktaESSKPLTDAEKQVAQQAKQTEslddvNARSRNEIEDLARIIMKITSTYDAQANLKMEIVPQGLRILV 172
Cdd:PRK07734  71 DQKPEDEK-----ELSASSLEAEQAKKKEEAEAK-----KKKEMEELKAVQKKIDQYIKEKQLSSSLQTKLTEEGLLITI 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 173 SDDQkreMFQRSSAILTPFFKRLLTEFAPEL--NKIDNkIIITGHTDATRFRDQVLYNNWNLSGERAMQARAVLTTGGLD 250
Cdd:PRK07734 141 LDNI---LFDSGKADVRLEDLPLAKEISNLLvsNPPRN-ITISGHTDNVPIANAQFASNWELSVMRAVNFMQVLLENKEL 216

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 501083135 251 QSKILQVSGMADqmlLDPQHPLSSA-----NRRIEIMVL 284
Cdd:PRK07734 217 DPEKFSAKGYGE---YKPIASNDTAegrakNRRVEVLIL 252
OmpA COG2885
Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins [Cell wall ...
 181-285 2.62e-10

Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442131 [Multi-domain]  Cd Length: 294  Bit Score: 60.18  E-value: 2.62e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 181 FQRSSAILTPFFKRLLTEFAPELNKIDN-KIIITGHTDATRFRDqvlYNNWnLSGERAMQARAVLTTGGLDQSKIlQVSG 259
Cdd:COG2885  191 FDFDSAELTPEAKAALDELAALLKENPDlRIEIEGHTDSRGSDA---YNLA-LSERRAEAVKDYLVSKGIPASRI-TAVG 265

                         90       100
                 ....*....|....*....|....*...
gi 501083135 260 MADQMLLDPQHPLS--SANRRIEIMVLT 285
Cdd:COG2885  266 YGESRPVASNDTEEgrAKNRRVEIVVLK 293
PRK07033 PRK07033
DotU family type VI secretion system protein;
159-284 2.55e-09

DotU family type VI secretion system protein;


Pssm-ID: 180801 [Multi-domain]  Cd Length: 427  Bit Score: 57.75  E-value: 2.55e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 159 LKMEIvPQGLrILVSDDQKR--------EMFQRSSAILTPFFKRLLTEFAPELNKIDNKIIITGHTDATRFRDQVLYNNW 230
Cdd:PRK07033 290 LEPEI-RAGL-VAVRDEADRsvvtlrgdGLFASASTSVRDRYQPVLARVADALNQVKGNVLVTGYSDNVPIRTARFPSNW 367

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 501083135 231 NLSGERAMQARAVLtTGGLDQSKILQVSGMADqmlLDPQHPLSSA-----NRRIEIMVL 284
Cdd:PRK07033 368 ELSQARAQAVRALL-AARLGQPERVTAEGRGD---SDPVAPNDSAenrarNRRVEITLL 422
PRK09038 PRK09038
flagellar motor protein MotD; Reviewed
 15-284 5.66e-09

flagellar motor protein MotD; Reviewed


Pssm-ID: 181618 [Multi-domain]  Cd Length: 281  Bit Score: 56.17  E-value: 5.66e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  15 SSRKSHDEFHGG--AWKVAFADFTLAMMALFMVLWIMGAVTEEERKEIVSMLNGesVFEG--NSLTPItqkegqggqlsl 90
Cdd:PRK09038   2 MRRRKHHEEHENheRWLVSYADFITLLFAFFVVMYAISSVNEGKYKVLSEALTG--AFNGpsRSMKPI------------ 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  91 idsrhPKTPKPSKTAESSKPLTDAEKQVAQQAKQTeslddvnarsrneIEDLARIIMKITSTYDAQANLKMEIVPQGLRI 170
Cdd:PRK09038  68 -----PIGKEQPKTTQPARPLVIDSEQPDARAQDQ-------------LKTIADDLRKALGPLIESGQVTVRRNELWIEI 129

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 171 LVSDDQkreMFQRSSAILTPFFKRLLTEFAPELNKIDNKIIITGHTDATRFRDQVLYNNWNLSGERAMQARAVLTTGGLD 250
Cdd:PRK09038 130 EINSSL---LFGSGDAMLSDQAFAILEKVAEVLKPAPNPIHVEGFTDNVPIATAQFPSNWELSAARAASVVRLLADDGVA 206

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 501083135 251 QSKILQVsGMADqmlldpQHPLSS--------ANRRIEIMVL 284
Cdd:PRK09038 207 PSRLAAV-GYGE------FQPVADndtaegraRNRRVVLVIL 241
PRK08126 PRK08126
hypothetical protein; Provisional
 159-283 5.94e-08

hypothetical protein; Provisional


Pssm-ID: 236157 [Multi-domain]  Cd Length: 432  Bit Score: 53.54  E-value: 5.94e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 159 LKMEIVpQGLrILVSDDQKRE--------MFQRSSAILTPFFKRLLTEFAPELNKIDNKIIITGHTDATRFRDQVLYNNW 230
Cdd:PRK08126 299 LKNEIA-RGT-LSVDEDARHSsvvfrgdaMFVPGQATVNPAMGPLIAKIAREIARVGGKVTVTGHTDNQPIRSAQFASNL 376

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 501083135 231 NLSGERAMQARAVLTTGGLDQSKILQVSGMADQMLLDPQHPLSSA-NRRIEIMV 283
Cdd:PRK08126 377 VLSEKRAAQVAQMLQSAGVPASRLEAVGKGDAQPVADNRTPQGRAqNRRVEITV 430
PRK06925 PRK06925
flagellar motor protein MotB;
1-284 6.45e-08

flagellar motor protein MotB;


Pssm-ID: 235887 [Multi-domain]  Cd Length: 230  Bit Score: 52.46  E-value: 6.45e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135   1 MRNRSKEHttiiKRSSRKshdefhggaWKVAFADFTLAMMALFMVLWIMGAVTEEERKEIVSMLngesvfegnsltpitQ 80
Cdd:PRK06925   1 MERRKRQQ----SKGSPK---------WMVTFSDLITLILVFFILLFSMSQIDAQKFKAAVESF---------------Q 52

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  81 KEGQGGQLslidsrhpktpkPSKTAESSKPLTDAEKQvaqqaKQTESLDDVNARSRNEIEDlARIIMKITSTYDAqanlk 160
Cdd:PRK06925  53 QRGSLGFL------------PSAIEFENPAESSEDEE-----KQEDQLDELLKKVNEYIEE-NELKSVITAKRDE----- 109

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 161 meivpqglRILVSDDQKREMFQRSSAILTPFFKRLLTEFAPELNKIDNKIIITGHTDATRFRDQVLYNNWNLSGERAMQA 240
Cdd:PRK06925 110 --------RGVVLVLQEAVLFETGEADILKQAEPFLHKIGVLLSTIPNDIKVEGHTDSRPISTYRYPSNWELSAARASSV 181

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 501083135 241 -RAVLTTGGLDQSKILQVsGMADQMLLDPQHPLS--SANRRIEIMVL 284
Cdd:PRK06925 182 iRYFTSKEKLDSSRFIAV-GYADTKPVVPNTTEEnmQENRRVEIVIS 227
motB PRK08457
flagellar motor protein MotB; Reviewed
 25-292 2.90e-06

flagellar motor protein MotB; Reviewed


Pssm-ID: 181435 [Multi-domain]  Cd Length: 257  Bit Score: 47.79  E-value: 2.90e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  25 GGAWKVAFADFTLAMMALFMVLWIMGAVTeeerKEIVSMLNGESV--FEGNSLTPITQKEgqggqlslidSRHPKTPKPS 102
Cdd:PRK08457  13 GEKWAVPYADFLSLLLALFIALYAISAVN----KAKVEALKTEFIkiFDYTAKPEVKQPV----------KVIPPDSGDA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 103 KTAESSKpltdaEKQVAQQAKQTESLDDVNARSRN--EIEDlaRIIMKITStydaqanlKMEIVPQGLRILVSDDQkrEM 180
Cdd:PRK08457  79 EEEMDEL-----KSLKASQNTQQETIERRKGEGGAldQIDN--GIALKLPS--------KLLFENGSAEIINADMM--DY 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 181 FQRSSAILTPFFKRLltefapelnkidnKIIITGHTDATRFRDQVLYNNWNLSGERAMQARAVLTTGGLDQSKiLQVSGM 260
Cdd:PRK08457 142 LKRIAKIITKLPKQV-------------KINVRGYTDNSPLNKSRYKDHYELAAARAYNVMKVLIQYGINPNR-LSFSSY 207

                        250       260       270
                 ....*....|....*....|....*....|....
gi 501083135 261 ADQMLLDPQHPLSSA--NRRIEIMVLTHSASDSL 292
Cdd:PRK08457 208 GSNNPIAPNDSLENRlkNNRVEIFFKVDANDTST 241
motB PRK06667
flagellar motor protein MotB; Validated
 11-285 1.84e-05

flagellar motor protein MotB; Validated


Pssm-ID: 180652 [Multi-domain]  Cd Length: 252  Bit Score: 45.17  E-value: 1.84e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  11 IIKRSSRKSHDEFHGGAWKVAFADFTLAMMALFMVLWIMGAVTEEERKEIVSMLNGESVFEGNsltpITQKEGQGGQLSL 90
Cdd:PRK06667   1 MAMRKKKCPKCIQGAPEYMLTYGDMVTLLLCFFVMLFTTNDVDENVLQIISASFTGTGFFKGG----QTLSKGKLSELGN 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  91 IDSRHPKTPKPSKTAESSKpltdaeKQVAQQAKQTESlddvnarsrNEI---EDLARIIMKITST---YDAQANLKMeiv 164
Cdd:PRK06667  77 SIMSLPSTEKGKQLSQAKK------NASSLFKPEIQS---------NKVavtEDERGLVISLASDaffYPGSAEVKL--- 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 165 pqglrilvsdDQKREMFQRSSAILTpffkrlltefapELNKIDNKIIITGHTDATRFRDQVLY-NNWNLSGERAMQARAV 243
Cdd:PRK06667 139 ----------EENRETLQKIASFIG------------FLDLAGRNFRIEGHTDNVDVNPEGPWkSNWELSGARAVNMLEY 196

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 501083135 244 LTTGGLDQSKILQVSGMAD-QMLLDPQHPLSSA-NRRIEIMVLT 285
Cdd:PRK06667 197 ILNYGDQSESWFQVSGFAGsRPLATEDTPEGRAyNRRIDIVILT 240
PRK06742 PRK06742
flagellar motor protein MotS; Reviewed
 90-283 2.32e-04

flagellar motor protein MotS; Reviewed


Pssm-ID: 102525 [Multi-domain]  Cd Length: 225  Bit Score: 41.59  E-value: 2.32e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135  90 LIDSRHPKTPKPSKTAESskpLTDAEKQVAQQAKQT-----ESLDDVNARSRNEIEDL-ARIIMKITSTYDAQANLKMEi 163
Cdd:PRK06742  30 LVATSKQDAVKLSKMLEK---FSDTEQVDAKVMENTipdisHEKNDEKMISKKRMDELyKKLKAYVDNNGISQVNVYRE- 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501083135 164 vPQGLRILVSDDQkreMFQRSSAILTPFFKRLLTEFAPELNKIDNKIIITGHTDATRFRDQVLYNNWNLSGERAMQARAV 243
Cdd:PRK06742 106 -DTGVSVVIVDNL---IFDTGDANVKPEAKEIISQLVGFFQSVPNPIVVEGHTDSRPIHNDKFPSNWELSSARAANMIHH 181

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 501083135 244 LTTGGLDQSKILQVSGMADQMLLDPQHPLSS--ANRRIEIMV 283
Cdd:PRK06742 182 LIEVYNVDDKRLAAVGYADTKPVVPNDSPQNweKNRRVVIYI 223
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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