|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05748 |
PRK05748 |
replicative DNA helicase; Provisional |
1-447 |
0e+00 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180232 [Multi-domain] Cd Length: 448 Bit Score: 868.12 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 1 MTELLDDRLPPQNIEAEQAVLGAVFLEPSALTLASEVLIPEDFYRMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLL 80
Cdd:PRK05748 1 MSEVAALRVPPQSIEAEQAVLGAIFLDPDALITVSEYLSPDDFYRHAHRLIFRAMLKLSDRGEPIDVVTVTEILDDQGDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 81 EEVGGISYLTDIANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGYTREDEVEDLLSDAEKTIMEVAQRKNSGAFQ 160
Cdd:PRK05748 81 EEVGGLSYLAELANSVPTAANIEYYAKIVAEKAMLRRLIRTATEIANDAYEPEDDADEILDEAEKKIFEVSERRNKSGFK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 161 NIKDVLVQTYDNIEQLHNRKGDITGIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSL 240
Cdd:PRK05748 161 NIKDVLVKAYDRIEMLHNQTGDITGIPTGFTDLDKMTSGLQPNDLIIVAARPSVGKTAFALNIAQNVATKTDKNVAIFSL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 241 EMGSEQLVMRMLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLKQEN-GLGMILI 319
Cdd:PRK05748 241 EMGAESLVMRMLCAEGNIDAQRLRTGQLTDDDWPKLTIAMGSLSDAPIYIDDTPGIKVTEIRARCRRLAQEHgGLGLILI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 320 DYLQLIQGSGRSSDNRQQEVSEISRALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRD 399
Cdd:PRK05748 321 DYLQLIQGSGRSGENRQQEVSEISRSLKALAKELKVPVIALSQLSRGVEQRQDKRPVMSDIRESGSIEQDADIVAFLYRD 400
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 500861317 400 DYYDKESENKNIIEIIIAKQRNGPVGTVSLAFVKEYNKFVNLERRFDD 447
Cdd:PRK05748 401 DYYDEETENKNTIEIIIAKQRNGPVGTVELAFQKEYNKFVNLARREED 448
|
|
| DnaB |
TIGR00665 |
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein ... |
10-442 |
0e+00 |
|
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273206 [Multi-domain] Cd Length: 432 Bit Score: 748.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 10 PPQNIEAEQAVLGAVFLEPSALTLASEVLIPEDFYRMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLLEEVGGISYL 89
Cdd:TIGR00665 1 PPHNIEAEQAVLGAILLDNEAIDDVAEILKPEDFYRPAHRLIFQAILDLYEKGEPIDLVTVAEELEKDGELEEVGGLAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 90 TDIANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGYTREDEVEDLLSDAEKTIMEVAQRKNSGAFQNIKDVLVQT 169
Cdd:TIGR00665 81 AELASNVPSAANIEYYAEIVKEKAILRRLIQAGTEIVELAYDPTGDVEELLDEAEQKIFEIAESRTSKGFKSIKEILKEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 170 YDNIEQLHNRKGDITGIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSLEMGSEQLVM 249
Cdd:TIGR00665 161 VEEIEELYERKGGITGVPTGFTDLDKLTSGLQPSDLIILAARPSMGKTAFALNIAENAAIKEGKPVAFFSLEMSAEQLVM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 250 RMLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLKQENGLGMILIDYLQLIQGSG 329
Cdd:TIGR00665 241 RMLSSESRVDSQKLRTGRLSDEDWEKLTEAAGELSEAPLYIDDTPGLTITELRAKARRLKREHGLGLIVIDYLQLMSGSG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 330 RsSDNRQQEVSEISRALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYDKESENK 409
Cdd:TIGR00665 321 R-SENRQQEVSEISRSLKALAKELNVPVIALSQLSRSVEQREDKRPQLSDLRESGSIEQDADIVMFLYRDEYYNPDSEDK 399
|
410 420 430
....*....|....*....|....*....|...
gi 500861317 410 NIIEIIIAKQRNGPVGTVSLAFVKEYNKFVNLE 442
Cdd:TIGR00665 400 GIAEIIIAKQRNGPTGTVKLAFLGEYTRFENLA 432
|
|
| DnaB |
COG0305 |
Replicative DNA helicase [Replication, recombination and repair]; |
13-442 |
0e+00 |
|
Replicative DNA helicase [Replication, recombination and repair];
Pssm-ID: 440074 [Multi-domain] Cd Length: 429 Bit Score: 733.03 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 13 NIEAEQAVLGAVFLEPSALTLASEVLIPEDFYRMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLLEEVGGISYLTDI 92
Cdd:COG0305 1 NIEAEQAVLGALLLDNDALDEVADILKPEDFYRPAHRLIFEAILDLYERGEPIDLVTVAEELEKRGELEEVGGAAYLAEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 93 ANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGYTREDEVEDLLSDAEKTIMEVAQRKNSGAFQNIKDVLVQTYDN 172
Cdd:COG0305 81 AENVPSAANIEYYARIVKEKALLRRLIEAGTEIVELAYDEDEDVDELLDEAEQKIFEIAEKRSSKGFVSISDILKEALER 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 173 IEQLHNRKGDITGIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSLEMGSEQLVMRML 252
Cdd:COG0305 161 IEELYKNGGGITGVPTGFTDLDKLTGGLQPGDLIILAARPSMGKTAFALNIARNAAIKEGKPVAIFSLEMSAEQLVMRLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 253 CAEGNINAQNLRTGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLKQENGLGMILIDYLQLIQGSGRsS 332
Cdd:COG0305 241 SSEARIDSSKLRTGKLSDEDWERLSSAAGELSEAPIYIDDTPGLTIAEIRAKARRLKREHGLGLIVIDYLQLMSGSGR-S 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 333 DNRQQEVSEISRALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYDKESENKNII 412
Cdd:COG0305 320 ENRQQEISEISRSLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGSIEQDADVVMFLYRDEYYNPDSEDKGIA 399
|
410 420 430
....*....|....*....|....*....|
gi 500861317 413 EIIIAKQRNGPVGTVSLAFVKEYNKFVNLE 442
Cdd:COG0305 400 EIIIAKQRNGPTGTVKLAFDGEYTRFENLA 429
|
|
| DnaB_C |
pfam03796 |
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
185-440 |
6.74e-173 |
|
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 427509 [Multi-domain] Cd Length: 254 Bit Score: 484.61 E-value: 6.74e-173
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 185 GIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSLEMGSEQLVMRMLCAEGNINAQNLR 264
Cdd:pfam03796 1 GLPTGFTDLDRLTGGLQPGDLIIIAARPSMGKTAFALNIARNAAVKHKKPVAIFSLEMSAEQLVMRLLASEAGVDSQKLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 265 TGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLKQENGLGMILIDYLQLIQGsGRSSDNRQQEVSEISR 344
Cdd:pfam03796 81 TGQLTDEDWEKLAKAAGRLSEAPLYIDDTPGLSIAEIRAKARRLKREHGLGLIVIDYLQLMSG-GSRGENRQQEISEISR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 345 ALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYDKEsENKNIIEIIIAKQRNGPV 424
Cdd:pfam03796 160 SLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGAIEQDADVVMFLYRDEYYNPK-EPEGKAEIIIAKQRNGPT 238
|
250
....*....|....*.
gi 500861317 425 GTVSLAFVKEYNKFVN 440
Cdd:pfam03796 239 GTVKLAFLGEYTRFEN 254
|
|
| DnaB_C |
cd00984 |
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase ... |
185-440 |
1.39e-152 |
|
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 410864 [Multi-domain] Cd Length: 256 Bit Score: 433.48 E-value: 1.39e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 185 GIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSLEMGSEQLVMRMLCAEGNINAQNLR 264
Cdd:cd00984 1 GLPTGFTDLDKLTGGLQPGDLIIIAARPSMGKTAFALNIAENIALDEGLPVLFFSLEMSAEQLAERLLSSESGVSLSKLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 265 TGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLKQENG-LGMILIDYLQLIQGSGRSsDNRQQEVSEIS 343
Cdd:cd00984 81 TGRLDDEDWERLTAAMGELSELPLYIDDTPGLTVDEIRAKARRLKREHGgLGLIVIDYLQLIRGSKRA-ENRQQEVAEIS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 344 RALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYDKESENKNIIEIIIAKQRNGP 423
Cdd:cd00984 160 RSLKALAKELNVPVIALSQLNRGVESRTDKRPMLSDLRESGSIEQDADVVIFLYRDEYYDKDSEDKGIAEIIIAKNRNGP 239
|
250
....*....|....*..
gi 500861317 424 VGTVSLAFVKEYNKFVN 440
Cdd:cd00984 240 TGTVYLAFNPEYTRFTD 256
|
|
| dnaB_SPI-7_type |
NF040583 |
SPI-7-type island replicative DNA helicase; Members of this family are DnaB-PI, a ... |
10-441 |
1.49e-143 |
|
SPI-7-type island replicative DNA helicase; Members of this family are DnaB-PI, a pathogenicity island (PI) variant of the replicative DNA helicase DnaB. Members are found with other conjugative element replication proteins such as ParA, ParB in genetic islands whose core proteins (but not cargo proteins) are shared with the Salmonella typhi SPI-7 island.
Pssm-ID: 468557 [Multi-domain] Cd Length: 434 Bit Score: 417.10 E-value: 1.49e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 10 PPQNIEAEQAVLGAVFLEPSALTLASEVLIPEDFYRMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLLEEVGGISYL 89
Cdd:NF040583 1 GPYSVEAEQSVLGGLMLDNDRWDDVALLLAADDFYSRAHRIIFRAMARLVSAGQPIDLITLSESLEQQGQLEQVGGFAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 90 TDIANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGYTREDEVEDLLSDAEKTIMEVAQRKNSGAFQNIKDVLVQT 169
Cdd:NF040583 81 AELSKNTPSAANIVAYAEIVAEYSRARQLLALGHDLSADASAPRADIADLLEQAEQRLFDIAEQAEPQQEVTLIEGLETL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 170 YDNIEQLHNRKGDITGIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQN-VATKTDESVAIFSLEMGSEQLV 248
Cdd:NF040583 161 VSELELRCQSGNGITGTPTGFAELDEMTCGLQPGDLILLAARPSMGKTALALAFCLGaLRGKPDKVVQIYSLEMPTEQLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 249 MRMLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSLS--NSGIFIDDTPGIRVSEIRSKCRRLKQENGL-GMILIDYLQLI 325
Cdd:NF040583 241 MRLVSMLGRVPLQRLRSGLLDDEDWARISQAMALLTdwKDRLIIDDTSYLTPALLRARARRNARKYGKpSLIMVDYLQLM 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 326 QGSGRssDNRQQEVSEISRALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYDKE 405
Cdd:NF040583 321 RCPGQ--ENRTQEIAEISRSLKALAKEMGCPVLALSQLNRQLESRADKRPNNGDLRDSGALEQDADLIMFIYRDEVYNPN 398
|
410 420 430
....*....|....*....|....*....|....*.
gi 500861317 406 SENKNIIEIIIAKQRNGPVGTVSLAFVKEYNKFVNL 441
Cdd:NF040583 399 TPDKGIAEIIIGKQRQGPTGTVKVQFDGRYTRFSDL 434
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05748 |
PRK05748 |
replicative DNA helicase; Provisional |
1-447 |
0e+00 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180232 [Multi-domain] Cd Length: 448 Bit Score: 868.12 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 1 MTELLDDRLPPQNIEAEQAVLGAVFLEPSALTLASEVLIPEDFYRMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLL 80
Cdd:PRK05748 1 MSEVAALRVPPQSIEAEQAVLGAIFLDPDALITVSEYLSPDDFYRHAHRLIFRAMLKLSDRGEPIDVVTVTEILDDQGDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 81 EEVGGISYLTDIANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGYTREDEVEDLLSDAEKTIMEVAQRKNSGAFQ 160
Cdd:PRK05748 81 EEVGGLSYLAELANSVPTAANIEYYAKIVAEKAMLRRLIRTATEIANDAYEPEDDADEILDEAEKKIFEVSERRNKSGFK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 161 NIKDVLVQTYDNIEQLHNRKGDITGIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSL 240
Cdd:PRK05748 161 NIKDVLVKAYDRIEMLHNQTGDITGIPTGFTDLDKMTSGLQPNDLIIVAARPSVGKTAFALNIAQNVATKTDKNVAIFSL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 241 EMGSEQLVMRMLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLKQEN-GLGMILI 319
Cdd:PRK05748 241 EMGAESLVMRMLCAEGNIDAQRLRTGQLTDDDWPKLTIAMGSLSDAPIYIDDTPGIKVTEIRARCRRLAQEHgGLGLILI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 320 DYLQLIQGSGRSSDNRQQEVSEISRALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRD 399
Cdd:PRK05748 321 DYLQLIQGSGRSGENRQQEVSEISRSLKALAKELKVPVIALSQLSRGVEQRQDKRPVMSDIRESGSIEQDADIVAFLYRD 400
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 500861317 400 DYYDKESENKNIIEIIIAKQRNGPVGTVSLAFVKEYNKFVNLERRFDD 447
Cdd:PRK05748 401 DYYDEETENKNTIEIIIAKQRNGPVGTVELAFQKEYNKFVNLARREED 448
|
|
| DnaB |
TIGR00665 |
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein ... |
10-442 |
0e+00 |
|
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273206 [Multi-domain] Cd Length: 432 Bit Score: 748.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 10 PPQNIEAEQAVLGAVFLEPSALTLASEVLIPEDFYRMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLLEEVGGISYL 89
Cdd:TIGR00665 1 PPHNIEAEQAVLGAILLDNEAIDDVAEILKPEDFYRPAHRLIFQAILDLYEKGEPIDLVTVAEELEKDGELEEVGGLAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 90 TDIANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGYTREDEVEDLLSDAEKTIMEVAQRKNSGAFQNIKDVLVQT 169
Cdd:TIGR00665 81 AELASNVPSAANIEYYAEIVKEKAILRRLIQAGTEIVELAYDPTGDVEELLDEAEQKIFEIAESRTSKGFKSIKEILKEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 170 YDNIEQLHNRKGDITGIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSLEMGSEQLVM 249
Cdd:TIGR00665 161 VEEIEELYERKGGITGVPTGFTDLDKLTSGLQPSDLIILAARPSMGKTAFALNIAENAAIKEGKPVAFFSLEMSAEQLVM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 250 RMLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLKQENGLGMILIDYLQLIQGSG 329
Cdd:TIGR00665 241 RMLSSESRVDSQKLRTGRLSDEDWEKLTEAAGELSEAPLYIDDTPGLTITELRAKARRLKREHGLGLIVIDYLQLMSGSG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 330 RsSDNRQQEVSEISRALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYDKESENK 409
Cdd:TIGR00665 321 R-SENRQQEVSEISRSLKALAKELNVPVIALSQLSRSVEQREDKRPQLSDLRESGSIEQDADIVMFLYRDEYYNPDSEDK 399
|
410 420 430
....*....|....*....|....*....|...
gi 500861317 410 NIIEIIIAKQRNGPVGTVSLAFVKEYNKFVNLE 442
Cdd:TIGR00665 400 GIAEIIIAKQRNGPTGTVKLAFLGEYTRFENLA 432
|
|
| DnaB |
COG0305 |
Replicative DNA helicase [Replication, recombination and repair]; |
13-442 |
0e+00 |
|
Replicative DNA helicase [Replication, recombination and repair];
Pssm-ID: 440074 [Multi-domain] Cd Length: 429 Bit Score: 733.03 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 13 NIEAEQAVLGAVFLEPSALTLASEVLIPEDFYRMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLLEEVGGISYLTDI 92
Cdd:COG0305 1 NIEAEQAVLGALLLDNDALDEVADILKPEDFYRPAHRLIFEAILDLYERGEPIDLVTVAEELEKRGELEEVGGAAYLAEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 93 ANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGYTREDEVEDLLSDAEKTIMEVAQRKNSGAFQNIKDVLVQTYDN 172
Cdd:COG0305 81 AENVPSAANIEYYARIVKEKALLRRLIEAGTEIVELAYDEDEDVDELLDEAEQKIFEIAEKRSSKGFVSISDILKEALER 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 173 IEQLHNRKGDITGIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSLEMGSEQLVMRML 252
Cdd:COG0305 161 IEELYKNGGGITGVPTGFTDLDKLTGGLQPGDLIILAARPSMGKTAFALNIARNAAIKEGKPVAIFSLEMSAEQLVMRLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 253 CAEGNINAQNLRTGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLKQENGLGMILIDYLQLIQGSGRsS 332
Cdd:COG0305 241 SSEARIDSSKLRTGKLSDEDWERLSSAAGELSEAPIYIDDTPGLTIAEIRAKARRLKREHGLGLIVIDYLQLMSGSGR-S 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 333 DNRQQEVSEISRALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYDKESENKNII 412
Cdd:COG0305 320 ENRQQEISEISRSLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGSIEQDADVVMFLYRDEYYNPDSEDKGIA 399
|
410 420 430
....*....|....*....|....*....|
gi 500861317 413 EIIIAKQRNGPVGTVSLAFVKEYNKFVNLE 442
Cdd:COG0305 400 EIIIAKQRNGPTGTVKLAFDGEYTRFENLA 429
|
|
| PRK05595 |
PRK05595 |
replicative DNA helicase; Provisional |
8-442 |
0e+00 |
|
replicative DNA helicase; Provisional
Pssm-ID: 235525 [Multi-domain] Cd Length: 444 Bit Score: 561.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 8 RLPPQNIEAEQAVLGAVFLEPSALTLASEVLIPEDFYRMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLLEEVGGIS 87
Cdd:PRK05595 6 RSLPQSIEAEQSVLGAMIIDKTSIAEAAEVLKSEDFYRDSHKVIFSAIIELYQKDIAVDMLTLTENLKSTDKLEAAGGVT 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 88 YLTDIANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGYTREDEVEDLLSDAEKTIMEVAQRKNSGAFQNIKDVLV 167
Cdd:PRK05595 86 YITELSNSIVSTANIQSYIKIVKDKSTLRRLIKSSTEIIENSYNNQDDVEKVIDSAEKKIFDISEKRTTSDFEPLSNVLE 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 168 QTYDNIEQLHNRKGDITGIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSLEMGSEQL 247
Cdd:PRK05595 166 RGFEQIENLFNNKGETTGVASGFRELDAKTSGFQKGDMILIAARPSMGKTTFALNIAEYAALREGKSVAIFSLEMSKEQL 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 248 VMRMLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLKQENGLGMILIDYLQLIQG 327
Cdd:PRK05595 246 AYKLLCSEANVDMLRLRTGNLEDKDWENIARASGPLAAAKIFIDDTAGVSVMEMRSKCRRLKIEHGIDMILIDYLQLMSG 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 328 SGrSSDNRQQEVSEISRALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYDKESE 407
Cdd:PRK05595 326 GK-GSESRQQEVSEISRSIKALAKEMECPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRDEYYNKETE 404
|
410 420 430
....*....|....*....|....*....|....*
gi 500861317 408 NKNIIEIIIAKQRNGPVGTVSLAFVKEYNKFVNLE 442
Cdd:PRK05595 405 DKNVAECIIAKQRNGPTGTVKLAWLGQYSKFGNLD 439
|
|
| PRK07773 |
PRK07773 |
replicative DNA helicase; Validated |
7-392 |
0e+00 |
|
replicative DNA helicase; Validated
Pssm-ID: 236093 [Multi-domain] Cd Length: 886 Bit Score: 532.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 7 DRLPPQNIEAEQAVLGAVFLEPSALTLASEVLIPEDFYRMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLLEEVGGI 86
Cdd:PRK07773 21 GRQPPQDLAAEQSVLGGMLLSKEAIARVLERLRPGAFYRPAHQNIYDAILDLYGRGEPADLVTVAAELDRRGLLERIGGA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 87 SYLTDIANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGYTREDEVEDLLSDAEKTIMEVAQRKNSGAFQNIKDVL 166
Cdd:PRK07773 101 PYLHTLISTVPTAANADYYARIVAEKALLRRLIEAGTRIVQYGYAEGADVAEVVDRAQAEIYDVTDRRLSEDFVALEDLL 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 167 VQTYDNIEQLHNRKGDITGIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSLEMGSEQ 246
Cdd:PRK07773 181 QPTFDEIDAIASSGGLARGVPTGFTELDAMTNGLHPGQLIIVAARPSMGKTTFGLDFARNCAIRHRLAVAIFSLEMSKEQ 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 247 LVMRMLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLKQENGLGMILIDYLQLIQ 326
Cdd:PRK07773 261 LVMRLLSAEAKIKLSDMRSGRMSDDDWTRLARAMGEISEAPIFIDDTPNLTVMEIRAKARRLRQEANLGLIVVDYLQLMT 340
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 500861317 327 GsGRSSDNRQQEVSEISRALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADI 392
Cdd:PRK07773 341 S-GKKYENRQQEVSEISRHLKLLAKELEVPVVALSQLSRGVEQRTDKRPMLSDLRESGCLTGDTLI 405
|
|
| DnaB_C |
pfam03796 |
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
185-440 |
6.74e-173 |
|
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 427509 [Multi-domain] Cd Length: 254 Bit Score: 484.61 E-value: 6.74e-173
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 185 GIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSLEMGSEQLVMRMLCAEGNINAQNLR 264
Cdd:pfam03796 1 GLPTGFTDLDRLTGGLQPGDLIIIAARPSMGKTAFALNIARNAAVKHKKPVAIFSLEMSAEQLVMRLLASEAGVDSQKLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 265 TGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLKQENGLGMILIDYLQLIQGsGRSSDNRQQEVSEISR 344
Cdd:pfam03796 81 TGQLTDEDWEKLAKAAGRLSEAPLYIDDTPGLSIAEIRAKARRLKREHGLGLIVIDYLQLMSG-GSRGENRQQEISEISR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 345 ALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYDKEsENKNIIEIIIAKQRNGPV 424
Cdd:pfam03796 160 SLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGAIEQDADVVMFLYRDEYYNPK-EPEGKAEIIIAKQRNGPT 238
|
250
....*....|....*.
gi 500861317 425 GTVSLAFVKEYNKFVN 440
Cdd:pfam03796 239 GTVKLAFLGEYTRFEN 254
|
|
| PRK09165 |
PRK09165 |
replicative DNA helicase; Provisional |
8-448 |
1.12e-160 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181676 [Multi-domain] Cd Length: 497 Bit Score: 463.20 E-value: 1.12e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 8 RLPPQNIEAEQAVLGAVFLEPSALTLASEVLIPEDFYRMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLLEEVGGIS 87
Cdd:PRK09165 19 RELPHNIEAEQALLGAILINNRALDRVSDFLKPEHFFEPLHQRIYEAIAKIIRKGKLATPVTLKTFLENDEALGELGGVQ 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 88 YLTDIANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGYTREDEVE--DLLSDAEKTIMEVA-QRKNSGAFQNIKD 164
Cdd:PRK09165 99 YLAKLATEAVTIINARDYGRIIYDLALRRELINIGEDVVNNAYDAPVDVApqEQIEDAEQKLYELAeTGRYEGGFQSFGT 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 165 VLVQTYDNIEQLHNRKGDITGIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVA--------------TK 230
Cdd:PRK09165 179 AITEAVDMANAAFKRDGHLSGISTGLRDLDSKLGGLHPSDLIILAGRPSMGKTALATNIAFNAAkayrreaqpdgskkAV 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 231 TDESVAIFSLEMGSEQLVMRMLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLKQ 310
Cdd:PRK09165 259 NGGVVGFFSLEMSAEQLATRILSEQSEISSSKIRRGKISEEDFEKLVDASQELQKLPLYIDDTPALSISQLRARARRLKR 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 311 ENGLGMILIDYLQLIQGSG-RSSDNRQQEVSEISRALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQD 389
Cdd:PRK09165 339 QHGLDLLVVDYLQLIRGSSkRSSDNRVQEISEITQGLKALAKELNIPVIALSQLSRQVEQRDDKRPQLSDLRESGSIEQD 418
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 500861317 390 ADIVAFLYRDDYYDKESENK-----------------NIIEIIIAKQRNGPVGTVSLAFVKEYNKFVNLERRFDDA 448
Cdd:PRK09165 419 ADVVMFVYREEYYLKRKEPRegtpkheewqekmekvhNKAEVIIAKQRHGPTGTVKLAFESEFTRFGDLADRSQLP 494
|
|
| PRK08760 |
PRK08760 |
replicative DNA helicase; Provisional |
8-441 |
2.37e-160 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181547 [Multi-domain] Cd Length: 476 Bit Score: 461.69 E-value: 2.37e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 8 RLPPQNIEAEQAVLGAVFLEPSALTLASEVLIPEDFYRMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLLEEVGGIS 87
Cdd:PRK08760 31 RVPPHSVEAEQAVLGGLMLAPDALDRVNDQLTENDFYRRDHRLIYRAIRELSEKDRPFDAVTLGEWFESQGKLEQVGDGA 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 88 YLTDIANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGYTRED-EVEDLLSDAEKTIMEVAQRKNSGAfQNIKDVL 166
Cdd:PRK08760 111 YLIELASTTPSAANIAAYAEIVRDKAVLRQLIEVGTTIVNDGFQPEGrESIELLASAEKAVFKIAEAGARGR-TDFVAMP 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 167 VQTYDNIEQLHNR---KGDITGIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSLEMG 243
Cdd:PRK08760 190 GALKDAFEELRNRfenGGNITGLPTGYNDFDAMTAGLQPTDLIILAARPAMGKTTFALNIAEYAAIKSKKGVAVFSMEMS 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 244 SEQLVMRMLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLKQENGLGMILIDYLQ 323
Cdd:PRK08760 270 ASQLAMRLISSNGRINAQRLRTGALEDEDWARVTGAIKMLKETKIFIDDTPGVSPEVLRSKCRRLKREHDLGLIVIDYLQ 349
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 324 LIQGSGrSSDNRQQEVSEISRALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYD 403
Cdd:PRK08760 350 LMSVPG-NSENRATEISEISRSLKGLAKELNVPVIALSQLNRSLETRTDKRPVMADLRESGAIEQDADMIVFIYRDDYYN 428
|
410 420 430
....*....|....*....|....*....|....*....
gi 500861317 404 KE-SENKNIIEIIIAKQRNGPVGTVSLAFVKEYNKFVNL 441
Cdd:PRK08760 429 KEnSPDKGLAEIIIGKHRGGPTGSCKLKFFGEYTRFDNL 467
|
|
| PRK07004 |
PRK07004 |
replicative DNA helicase; Provisional |
8-440 |
1.18e-158 |
|
replicative DNA helicase; Provisional
Pssm-ID: 235907 [Multi-domain] Cd Length: 460 Bit Score: 456.68 E-value: 1.18e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 8 RLPPQNIEAEQAVLGAVFLEPSALTLASEVLIPEDFYRMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLLEEVGGIS 87
Cdd:PRK07004 13 KVPPHSIEAEQSVLGGLLLDNAAWDRIADFLSQSDFYRYDHRIIFEHIGRLIAATRPADVITVYEALTTSGKAEEVGGLA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 88 YLTDIANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGYTRE-DEVEDLLSDAEKTIMEVAQRKNSGA--FQNIKD 164
Cdd:PRK07004 93 YLNALAQNTPSAANIRRYAEIVRDRAVLRRLVSVADEISADAFNPQgKEVRQLLDEAESKVFSIAEEGARGTqgFLEIGP 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 165 VLVQTYDNIEQLHNRKG--DITGIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSLEM 242
Cdd:PRK07004 173 LLTQVVERIDTLYHTANpsDVTGTPTGFVDLDRMTSGMHGGELIIVAGRPSMGKTAFSMNIGEYVAVEYGLPVAVFSMEM 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 243 GSEQLVMRMLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLKQENG-LGMILIDY 321
Cdd:PRK07004 253 PGTQLAMRMLGSVGRLDQHRMRTGRLTDEDWPKLTHAVQKMSEAQLFIDETGGLNPMELRSRARRLARQCGkLGLIIIDY 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 322 LQLIQGSGrSSDNRQQEVSEISRALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDY 401
Cdd:PRK07004 333 LQLMSGSS-QGENRATEISEISRSLKSLAKELDVPVIALSQLNRGLEQRPNKRPVMSDLRESGAIEQDADVILFIYRDEV 411
|
410 420 430
....*....|....*....|....*....|....*....
gi 500861317 402 YDKESENKNIIEIIIAKQRNGPVGTVSLAFVKEYNKFVN 440
Cdd:PRK07004 412 YNPDSPDKGTAEIIIGKQRNGPIGPVRLTFLGQYTKFDN 450
|
|
| DnaB_C |
cd00984 |
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase ... |
185-440 |
1.39e-152 |
|
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 410864 [Multi-domain] Cd Length: 256 Bit Score: 433.48 E-value: 1.39e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 185 GIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSLEMGSEQLVMRMLCAEGNINAQNLR 264
Cdd:cd00984 1 GLPTGFTDLDKLTGGLQPGDLIIIAARPSMGKTAFALNIAENIALDEGLPVLFFSLEMSAEQLAERLLSSESGVSLSKLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 265 TGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLKQENG-LGMILIDYLQLIQGSGRSsDNRQQEVSEIS 343
Cdd:cd00984 81 TGRLDDEDWERLTAAMGELSELPLYIDDTPGLTVDEIRAKARRLKREHGgLGLIVIDYLQLIRGSKRA-ENRQQEVAEIS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 344 RALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYDKESENKNIIEIIIAKQRNGP 423
Cdd:cd00984 160 RSLKALAKELNVPVIALSQLNRGVESRTDKRPMLSDLRESGSIEQDADVVIFLYRDEYYDKDSEDKGIAEIIIAKNRNGP 239
|
250
....*....|....*..
gi 500861317 424 VGTVSLAFVKEYNKFVN 440
Cdd:cd00984 240 TGTVYLAFNPEYTRFTD 256
|
|
| PRK05636 |
PRK05636 |
replicative DNA helicase; Provisional |
3-443 |
4.19e-150 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180177 [Multi-domain] Cd Length: 505 Bit Score: 436.58 E-value: 4.19e-150
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 3 ELLDDRLPPQNIEAEQAVLGAVFLEPSALTLASEVLIPEDFYRMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLLEE 82
Cdd:PRK05636 63 EYRDFRQPPYDNEAEQGVLGAMLLSPDTVIDIVEVLTPEDFYRPAHQLIFQAIIDLFSDNKEIDPVIVAGRLDRTNDLER 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 83 VGGISYLTDIANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGY--TREDEVEDLLSDAEKTIMEVAQRKNSGAFQ 160
Cdd:PRK05636 143 VGGAPYLHTLIQSVPTAANARYYAEIVSEKAVLRRLVDAGTRVVQLGYegDEGAEIDSVIDRAQQEVFAVSQKNQSEDYA 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 161 NIKDVLVQTYDNIEQLHNRKGDITGIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSL 240
Cdd:PRK05636 223 VLADILDPTMDELEMLSSQGGIATGIPTGFKDLDDLTNGLRGGQMIIVAARPGVGKSTLALDFMRSASIKHNKASVIFSL 302
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 241 EMGSEQLVMRMLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLKQENGLGMILID 320
Cdd:PRK05636 303 EMSKSEIVMRLLSAEAEVRLSDMRGGKMDEDAWEKLVQRLGKIAQAPIFIDDSANLTMMEIRSKARRLKQKHDLKLIVVD 382
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 321 YLQLIQgSGRSSDNRQQEVSEISRALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDD 400
Cdd:PRK05636 383 YLQLMS-SGKRVESRQQEVSEFSRQLKLLAKELDVPLIAISQLNRGPESRTDKRPQLADLRESGSLEQDADMVMLLYRPD 461
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 500861317 401 YYDKESENKNIIEIIIAKQRNGPVGTVSLAFVKEYNKFVNLER 443
Cdd:PRK05636 462 SQDKDDERAGEADIILAKHRGGPIDTVQVAHQLHYSRFVDMAR 504
|
|
| PRK06904 |
PRK06904 |
replicative DNA helicase; Validated |
9-447 |
2.59e-145 |
|
replicative DNA helicase; Validated
Pssm-ID: 136106 [Multi-domain] Cd Length: 472 Bit Score: 423.25 E-value: 2.59e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 9 LPPQNIEAEQAVLGAVFLEPSALTLASEVLIPEDFYRMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLLEEVGGISY 88
Cdd:PRK06904 22 IPPHSIEAEQAVLGGIMLDNRHWDSVAERVIADDFYTFEHRIIFQEMELLFRQNTPIDLLTLDQALKTKGKSDEVGGFAY 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 89 LTDIANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGYT-REDEVEDLLSDAEKTIMEVAQRKNSG--AFQNIKDV 165
Cdd:PRK06904 102 LAELSNNTPSAANILAYADIVREKAILRELISVGNNIAKNAYSpKGQDIKDILDEAERDVFSIAEKRTTAneGPQNVINL 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 166 LVQTYDNIEQLHNRKGD--ITGIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSLEMG 243
Cdd:PRK06904 182 LENTIDKIENLAATPTNngVTGVTTGFTDLDKKTAGLQPSDLIIVAARPSMGKTTFAMNLCENAAMASEKPVLVFSLEMP 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 244 SEQLVMRMLCAEGNINAQNLRTG-NLTEEDWGKLTMAMGSLSN-SGIFIDDTPGIRVSEIRSKCRRLKQENG-LGMILID 320
Cdd:PRK06904 262 AEQIMMRMLASLSRVDQTKIRTGqNLDQQDWAKISSTVGMFKQkPNLYIDDSSGLTPTELRSRARRVYRENGgLSLIMVD 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 321 YLQLIQGSGrSSDNRQQEVSEISRALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDD 400
Cdd:PRK06904 342 YLQLMRAPG-FEDNRTLEIAEISRSLKALAKELKVPVVALSQLNRTLENRGDKRPVNSDLRESGSIEQDADLIMFIYRDE 420
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 500861317 401 YYDKESE-NKNIIEIIIAKQRNGPVGTVSLAFVKEYNKFVNL--ERRFDD 447
Cdd:PRK06904 421 VYNETTEdNKGVAEIIIGKQRNGPIGRVRLAFQGQYSRFDNLanIPQYYD 470
|
|
| dnaB_SPI-7_type |
NF040583 |
SPI-7-type island replicative DNA helicase; Members of this family are DnaB-PI, a ... |
10-441 |
1.49e-143 |
|
SPI-7-type island replicative DNA helicase; Members of this family are DnaB-PI, a pathogenicity island (PI) variant of the replicative DNA helicase DnaB. Members are found with other conjugative element replication proteins such as ParA, ParB in genetic islands whose core proteins (but not cargo proteins) are shared with the Salmonella typhi SPI-7 island.
Pssm-ID: 468557 [Multi-domain] Cd Length: 434 Bit Score: 417.10 E-value: 1.49e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 10 PPQNIEAEQAVLGAVFLEPSALTLASEVLIPEDFYRMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLLEEVGGISYL 89
Cdd:NF040583 1 GPYSVEAEQSVLGGLMLDNDRWDDVALLLAADDFYSRAHRIIFRAMARLVSAGQPIDLITLSESLEQQGQLEQVGGFAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 90 TDIANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGYTREDEVEDLLSDAEKTIMEVAQRKNSGAFQNIKDVLVQT 169
Cdd:NF040583 81 AELSKNTPSAANIVAYAEIVAEYSRARQLLALGHDLSADASAPRADIADLLEQAEQRLFDIAEQAEPQQEVTLIEGLETL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 170 YDNIEQLHNRKGDITGIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQN-VATKTDESVAIFSLEMGSEQLV 248
Cdd:NF040583 161 VSELELRCQSGNGITGTPTGFAELDEMTCGLQPGDLILLAARPSMGKTALALAFCLGaLRGKPDKVVQIYSLEMPTEQLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 249 MRMLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSLS--NSGIFIDDTPGIRVSEIRSKCRRLKQENGL-GMILIDYLQLI 325
Cdd:NF040583 241 MRLVSMLGRVPLQRLRSGLLDDEDWARISQAMALLTdwKDRLIIDDTSYLTPALLRARARRNARKYGKpSLIMVDYLQLM 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 326 QGSGRssDNRQQEVSEISRALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYDKE 405
Cdd:NF040583 321 RCPGQ--ENRTQEIAEISRSLKALAKEMGCPVLALSQLNRQLESRADKRPNNGDLRDSGALEQDADLIMFIYRDEVYNPN 398
|
410 420 430
....*....|....*....|....*....|....*.
gi 500861317 406 SENKNIIEIIIAKQRNGPVGTVSLAFVKEYNKFVNL 441
Cdd:NF040583 399 TPDKGIAEIIIGKQRQGPTGTVKVQFDGRYTRFSDL 434
|
|
| PRK08840 |
PRK08840 |
replicative DNA helicase; Provisional |
8-447 |
1.95e-143 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181562 [Multi-domain] Cd Length: 464 Bit Score: 418.24 E-value: 1.95e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 8 RLPPQNIEAEQAVLGAVFLEPSALTLASEVLIPEDFYRMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLLEEVGGIS 87
Cdd:PRK08840 18 KVPPHSLEAEQSVIGGLLLDNERWDTVAEKVVASDFYSRPHRLIFEGVKSILEAGKPLDLITLSEHLERREQLEDVGGFA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 88 YLTDIANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGYTREDEV-EDLLSDAEKTIMEVAQRK---NSGAfQNIK 163
Cdd:PRK08840 98 YLADLAKNTPSAANINAYADIVAERALVRNLIGVANEIADAGYDPQGRTsEDLLDMAESKVFAIAEARtseNEGP-QNVD 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 164 DVLVQTYDNIEQLHNRKGD-ITGIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSLEM 242
Cdd:PRK08840 177 SILEKTLERIELLYKTPQDgVTGVDTGFTDLNKKTAGLQGSDLIIVAARPSMGKTTFAMNLCENAAMDQDKPVLIFSLEM 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 243 GSEQLVMRMLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSL-SNSGIFIDDTPGIRVSEIRSKCRRLKQEN-GLGMILID 320
Cdd:PRK08840 257 PAEQLMMRMLASLSRVDQTKIRTGQLDDEDWARISSTMGILmEKKNMYIDDSSGLTPTEVRSRARRIAREHgGLSMIMVD 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 321 YLQLIQGSGRSsDNRQQEVSEISRALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDD 400
Cdd:PRK08840 337 YLQLMRVPALS-DNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDE 415
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 500861317 401 YYDKESENKNIIEIIIAKQRNGPVGTVSLAFVKEYNKFVNLE-RRFDD 447
Cdd:PRK08840 416 VYNPDSPLKGTAEIIIGKQRNGPIGSVRLTFQGQYSRFDNYAgPAFDD 463
|
|
| phage_DnaB |
TIGR03600 |
phage replicative helicase, DnaB family, HK022 subfamily; Members of this family are phage (or ... |
13-431 |
1.50e-142 |
|
phage replicative helicase, DnaB family, HK022 subfamily; Members of this family are phage (or prophage-region) homologs of the bacterial homohexameric replicative helicase DnaB. Some phage may rely on host DnaB, while others encode their own verions. This model describes the largest phage-specific clade among the close homologs of DnaB, but there are, or course, other DnaB homologs from phage that fall outside the scope of this model. [Mobile and extrachromosomal element functions, Prophage functions]
Pssm-ID: 274672 [Multi-domain] Cd Length: 420 Bit Score: 414.11 E-value: 1.50e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 13 NIEAEQAVLGAVFLEPSALTLASEVLIPEDFYRMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLLEEVGGISYLTDI 92
Cdd:TIGR03600 1 SIEAEQAVLGGLLLDNDFIERVMAILKPEHFYSQDHRIIFEAMLDMFAENRPVDPLTLADKLEAEGEAEKVGGLAYLAEI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 93 ANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGYTREDE-VEDLLSDAEKTIMEVAQRKNS-GAFQNIKDVLVQTY 170
Cdd:TIGR03600 81 SNNTPSAANISSYARIVREKAKERKLIAACQRIITLACSPDGGtAEQKVEEAQAALLALTMSDGQeDGFVTFGEVLEDVV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 171 DNIEQLHNRKGDITGIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSLEMGSEQLVMR 250
Cdd:TIGR03600 161 RDLDKRFNPKGELTGLSTGLPKLDRLTNGLVKGDLIVIGARPSMGKTTLALNIAENVALREGKPVLFFSLEMSAEQLGER 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 251 MLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLKQE-NGLGMILIDYLQLIQGSG 329
Cdd:TIGR03600 241 LLASKSGINTGNIRTGRFNDSEFNRLLNAVDRLSEKDLYIDDTGGLTVAQIRSIARRIKRKkGGLDLIVVDYIQLMAPAR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 330 RSsdNRQQEVSEISRALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYDKESENK 409
Cdd:TIGR03600 321 GR--DRNEELGGISRGLKALAKELDVPVVLLAQLNRGSEKRTDKRPIMSDLRDSGAIEQDADVIGLIHREGYYDAREPPA 398
|
410 420
....*....|....*....|..
gi 500861317 410 NIIEIIIAKQRNGPVGTVSLAF 431
Cdd:TIGR03600 399 GIAELILAKNRHGPTGTVELLF 420
|
|
| PRK08006 |
PRK08006 |
replicative DNA helicase DnaB; |
8-440 |
1.20e-141 |
|
replicative DNA helicase DnaB;
Pssm-ID: 181193 [Multi-domain] Cd Length: 471 Bit Score: 414.02 E-value: 1.20e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 8 RLPPQNIEAEQAVLGAVFLEPSALTLASEVLIPEDFYRMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLLEEVGGIS 87
Cdd:PRK08006 25 KVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGFA 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 88 YLTDIANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGYTREDEV-EDLLSDAEKTIMEVAQR---KNSGAfQNIK 163
Cdd:PRK08006 105 YLAELSKNTPSAANISAYADIVRERAVVREMISVANEIADAGYDPQGRTsEDLLDLAESRVFQIAESranKDEGP-KNIA 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 164 DVLVQTYDNIEQLHNRKGD-ITGIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSLEM 242
Cdd:PRK08006 184 DILDATVARIEQLFQQPHDgVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLCENAAMLQDKPVLIFSLEM 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 243 GSEQLVMRMLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSL-SNSGIFIDDTPGIRVSEIRSKCRRLKQEN-GLGMILID 320
Cdd:PRK08006 264 PGEQIMMRMLASLSRVDQTRIRTGQLDDEDWARISGTMGILlEKRNMYIDDSSGLTPTEVRSRARRIFREHgGLSLIMID 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 321 YLQLIQGSGRSsDNRQQEVSEISRALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDD 400
Cdd:PRK08006 344 YLQLMRVPSLS-DNRTLEIAEISRSLKALAKELQVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDE 422
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 500861317 401 YYDKESENKNIIEIIIAKQRNGPVGTVSLAFVKEYNKFVN 440
Cdd:PRK08006 423 VYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDN 462
|
|
| PRK08506 |
PRK08506 |
replicative DNA helicase; Provisional |
12-439 |
1.60e-139 |
|
replicative DNA helicase; Provisional
Pssm-ID: 236278 [Multi-domain] Cd Length: 472 Bit Score: 408.24 E-value: 1.60e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 12 QNIEAEQAVLGAVFLEPSALTLASEVLIPEDFYRMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLLEEvggiSYLTD 91
Cdd:PRK08506 5 YDLDIERAVLSSILFSPDKFEEIASVLEPKDFYLPAHQDIFEAMLKLHNEDEPIDEEFIRKKLPKDKKIDE----EILLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 92 I--ANSVptaANIEYYAKIVEEKSILRRLIRTATTIAQDGYTREDEVEDLLSDAEKTIMEVAQRKNSGAFQNIKDVLVQT 169
Cdd:PRK08506 81 IlaTNPI---DNIEAYVEEIKEKSIKRELLSLANTIPEQAVEEDQKSSDILDEVERELYSITNGSNSEDFKDSKEVIEST 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 170 YDNIEQLHNRKG-DITGIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVaTKTDESVAIFSLEMGSEQLV 248
Cdd:PRK08506 158 MEHIKKQKRLGNkDIIGLDTGFVELNKMTKGFNKGDLIIIAARPSMGKTTLCLNMALKA-LNQDKGVAFFSLEMPAEQLM 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 249 MRMLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLK-QENGLGMILIDYLQLIQG 327
Cdd:PRK08506 237 LRMLSAKTSIPLQNLRTGDLDDDEWERLSDACDELSKKKLFVYDSGYVNIHQVRAQLRKLKsQHPEIGLAVIDYLQLMSG 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 328 SGRSSDnRQQEVSEISRALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYY----- 402
Cdd:PRK08506 317 SGNFKD-RHLQISEISRGLKLLARELDIPIIALSQLNRSLESRADKRPMLSDLRESGAIEQDADIILFVYRDDVYkeree 395
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 500861317 403 -DKESENKNIIEIII----------------AKQRNGPVGTVSLAFVKEYNKFV 439
Cdd:PRK08506 396 kEKEKKAKKEGKEERrihfqnksieeaeiiiGKNRNGPTGTVKLRFQKEFTRFV 449
|
|
| PRK06749 |
PRK06749 |
replicative DNA helicase; Provisional |
12-442 |
6.23e-129 |
|
replicative DNA helicase; Provisional
Pssm-ID: 168658 [Multi-domain] Cd Length: 428 Bit Score: 379.68 E-value: 6.23e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 12 QNIEAEQAVLGAVFLEPSaltLASEVLIPEDFYRM-SHQKIYNAMLVLGDRGEPVDLVTVTSELaNTDLLEEVGGISYLT 90
Cdd:PRK06749 4 QNVEAEKTVLGSLLLDGE---LIKECRLTEQYFSMpVHKSIFQLMRKMEDEGQPIDLVTFTSRV-DPNFLKGIGGMEYFI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 91 DIANSVPTAANIEYYAKIVEEKSILRRlirtATTIAQDGYTR--EDEVEDLLSDAEKTIMEVAQRKNSGAFqNIKDVLVQ 168
Cdd:PRK06749 80 GLMDGVPTTSNFSYYEGLVRGAWKMYQ----AGVLGHKMGERliAEKSEKIIGETITALCELEEKDCVCEF-DLKDALVD 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 169 TYdniEQLHNRKGDITGIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNvATKTDESVAIFSLEMGSEQLV 248
Cdd:PRK06749 155 LY---EELHQDAKEITGIETGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLH-AAKSGAAVGLFSLEMSSKQLL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 249 MRMLCAEGNINAQNLRTGN--LTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLKQENGLG--MILIDYLQL 324
Cdd:PRK06749 231 KRMASCVGEVSGGRLKNPKhrFAMEDWEKVSKAFAEIGELPLEIYDNAGVTVQDIWMQTRKLKRKHGDKkiLIIVDYLQL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 325 IQGSGRSSDNRQQEVSEISRALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYDK 404
Cdd:PRK06749 311 ITGDPKHKGNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADVIMLMYREDYYDK 390
|
410 420 430
....*....|....*....|....*....|....*...
gi 500861317 405 ESENKNIIEIIIAKQRNGPVGTVSLAFVKEYNKFVNLE 442
Cdd:PRK06749 391 ETMQKEMTEIHVAKHRNGPVGSFKLRFLKEFGRFVEGG 428
|
|
| PRK06321 |
PRK06321 |
replicative DNA helicase; Provisional |
10-440 |
2.64e-128 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180528 [Multi-domain] Cd Length: 472 Bit Score: 379.96 E-value: 2.64e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 10 PPQNIEAEQAVLGAVFLEPSALTLASEVLIPEDFYRMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLLEEVGGISYL 89
Cdd:PRK06321 16 PPNSKESEMIVLGCMLTSVNYLNLAANQLQEDDFYFLEHKIIFRVLQDAFKSDKPIDVHLAGEELKRRNQLNVIGGPSYL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 90 TDIANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGYTREDEVEDLLSDAEKTIMEVAQRKNSGAFQNIKDV---- 165
Cdd:PRK06321 96 ITLAEFAGTSAYIEEYAEIIRSKSILRKMIQTAKEIEKKALEEPKDVATALDEAQNLLFKISQTTNLAQYVLVADKlkgl 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 166 --------LVQTYDNIEQ-LHNRKGD----ITGIPTGFSELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTD 232
Cdd:PRK06321 176 tsskdkpfLLQLQERQEAfQQSAQGDsspmISGIPTHFIDLDKMINGFSPSNLMILAARPAMGKTALALNIAENFCFQNR 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 233 ESVAIFSLEMGSEQLVMRMLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLKQEN 312
Cdd:PRK06321 256 LPVGIFSLEMTVDQLIHRIICSRSEVESKKISVGDLSGRDFQRIVSVVNEMQEHTLLIDDQPGLKITDLRARARRMKESY 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 313 GLGMILIDYLQLIQGSG--RSSDNRQQEVSEISRALKSLARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDA 390
Cdd:PRK06321 336 DIQFLIIDYLQLLSGSGnlRNSESRQTEISEISRMLKNLARELNIPILCLSQLSRKVEDRANHRPMMSDLRESGSIEQDS 415
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 500861317 391 DIVAFLYRDDYYDKeSENKNIIEIIIAKQRNGPVGTVSLAFVKEYNKFVN 440
Cdd:PRK06321 416 DLVMFLLRREYYDP-NDKPGTAELIVAKNRHGSIGSVPLVFEKEFARFRN 464
|
|
| DnaB |
pfam00772 |
DnaB-like helicase N terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
10-111 |
3.10e-40 |
|
DnaB-like helicase N terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This N-terminal domain is required both for interaction with other proteins in the primosome and for DnaB helicase activity.
Pssm-ID: 395624 [Multi-domain] Cd Length: 103 Bit Score: 139.68 E-value: 3.10e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 10 PPQNIEAEQAVLGAVFLEPSALTLASEVLIPEDFYRMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLLEEVGGISYL 89
Cdd:pfam00772 2 PPHNIEAEQAVLGALLLDPEAIDEVADILKPEDFYDPAHRLIFEAILDLYDKGEPIDPVTVAEELEKKGKLEDVGGIAYL 81
|
90 100
....*....|....*....|..
gi 500861317 90 TDIANSVPTAANIEYYAKIVEE 111
Cdd:pfam00772 82 AELAANVPSAANIEYYARIVKE 103
|
|
| PRK07773 |
PRK07773 |
replicative DNA helicase; Validated |
379-443 |
4.31e-16 |
|
replicative DNA helicase; Validated
Pssm-ID: 236093 [Multi-domain] Cd Length: 886 Bit Score: 80.95 E-value: 4.31e-16
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 500861317 379 DIRESGSIEQDADIVAFLYRDDYYDKESENKNIIEIIIAKQRNGPVGTVSLAFVKEYNKFVNLER 443
Cdd:PRK07773 821 GIIVHNSIEQDADVVILLYRPDYYDRDDPRGGEAEFIVAKHRNGPTGTVTLAFQLHLSRFANLAR 885
|
|
| RecA-like_Gp4D_helicase |
cd19483 |
RecA-like domain of Escherichia coli bacteriophage T7 Gp4D helicase; This family includes the ... |
206-422 |
7.71e-15 |
|
RecA-like domain of Escherichia coli bacteriophage T7 Gp4D helicase; This family includes the RecA-like domain of the Gp4D fragment of the Gene4 helicase-primase (Gp4) from bacteriophage T7. Gp4D (residues 241-566) is the minimal fragment of the Gp4 that forms hexameric rings, it contains the helicase domain and the linker connecting the helicase and primase domains. Helicases are ring-shaped oligomeric enzymes that unwind DNA at the replication fork; they couple NTP hydrolysis to the unwinding of nucleic acid duplexes into their component strands. This family belongs to the RecA-like NTPase superfamily which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410891 [Multi-domain] Cd Length: 231 Bit Score: 73.76 E-value: 7.71e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 206 IIVAARPSVGKTAFALNIAQNVATKTDESVAIFSLEMGSEQLVMRMLCAEGNINAQNLRTGnlTEEDWGKLTMAMGSLSN 285
Cdd:cd19483 1 VTIGAGSGIGKSTIVRELAYHLITEHGEKVGIISLEESVEETAKGLAGKHLGKPEPLELPR--DDITEEEEDDAFDNELG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 286 SG--IFIDDTPGIRVSEIRSKCRRLKQENGLGMILIDYLQLIqGSGRSSDNRQQEVSEISRALKSLARELEVPVIALSQL 363
Cdd:cd19483 79 SGrfFLYDHFGSLDWDNLKEKIRYMVKVLGCKVIVLDHLTIL-VSGLDSSDERKELDEIMTELAALVKELGVTIILVSHL 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 500861317 364 SR---GVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYDKESEnKNIIEIIIAKQRNG 422
Cdd:cd19483 158 RRpggGKGHEEGGEVSESDLRGSSAIAQLSDYVIGLERNKQADDPVE-RNTTRVRVLKNRFT 218
|
|
| PRK05973 |
PRK05973 |
replicative DNA helicase; Provisional |
204-381 |
9.73e-10 |
|
replicative DNA helicase; Provisional
Pssm-ID: 168322 [Multi-domain] Cd Length: 237 Bit Score: 58.89 E-value: 9.73e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 204 DLIIVAARPSVGKTAFALNIAQnVATKTDESVAIFSLEMgSEQLVMRMLCAegnINAQNLRTGNLTEedwgkltmamgsl 283
Cdd:PRK05973 65 DLVLLGARPGHGKTLLGLELAV-EAMKSGRTGVFFTLEY-TEQDVRDRLRA---LGADRAQFADLFE------------- 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 284 snsgifIDDTPGIRVSEIrskCRRLKQENGLGMILIDYLQLIqgsgrssDNRQQ--EVSEISRALKSLARELEVPVIALS 361
Cdd:PRK05973 127 ------FDTSDAICADYI---IARLASAPRGTLVVIDYLQLL-------DQRREkpDLSVQVRALKSFARERGLIIVFIS 190
|
170 180
....*....|....*....|
gi 500861317 362 QLSRGVEQRQDKRPMMSDIR 381
Cdd:PRK05973 191 QIDRSFDPSAKPLPDIRDVR 210
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
186-401 |
2.10e-09 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 57.62 E-value: 2.10e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 186 IPTGFSELDRMTA-GFQRNDLIIVAARPSVGKTAFALNIAQNVAtKTDESVAIFSLEMGSEQLVMRMlcAEGNINAQNLr 264
Cdd:COG0467 2 VPTGIPGLDELLGgGLPRGSSTLLSGPPGTGKTTLALQFLAEGL-RRGEKGLYVSFEESPEQLLRRA--ESLGLDLEEY- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 265 tgnlteEDWGKLTmamgslsnsgiFIDDTP---GIRVSEIRSKCRRLKQENGLGMILIDYLQLIqgsgRSSDNRQQEVSE 341
Cdd:COG0467 78 ------IESGLLR-----------IIDLSPeelGLDLEELLARLREAVEEFGAKRVVIDSLSGL----LLALPDPERLRE 136
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 342 ISRALKSLARELEVPVIALSQLsrgveqrqdkrPMMSDIRESGSIEQDADIVAFLYRDDY 401
Cdd:COG0467 137 FLHRLLRYLKKRGVTTLLTSET-----------GGLEDEATEGGLSYLADGVILLRYVEL 185
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
202-452 |
8.11e-07 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 50.67 E-value: 8.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 202 RNDLIIVAARPSVGKTAFALNIAQNVATKTD--------ESVAIFSLEMGSEQLVMRMlcaegniNAQNLRTGNLTEEDW 273
Cdd:COG3598 12 EGGVTLLAGPPGTGKSFLALQLAAAVAAGGPwlgrrvppGKVLYLAAEDDRGELRRRL-------KALGADLGLPFADLD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 274 GKLTMAmgslsNSGIFIDDTPGIrvseirskcRRLKQ---ENGLGMILIDYLQ-LIQGsgrsSDNRQQEVSEISRALKSL 349
Cdd:COG3598 85 GRLRLL-----SLAGDLDDTDDL---------EALERaieEEGPDLVVIDPLArVFGG----DENDAEEMRAFLNPLDRL 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 350 ARELEVPVIALSQLSRGveqrQDKRPMMSDIRESGSIEQDADIVAFLYRDdyydkesENKNIIEIIIAKQRNGP------ 423
Cdd:COG3598 147 AERTGAAVLLVHHTGKG----GAGKDSGDRARGSSALRGAARSVLVLSRE-------KGEDLRVLTRAKSNYGPeialrw 215
|
250 260 270
....*....|....*....|....*....|
gi 500861317 424 -VGTVSLAFVKEYNKFVNLERRFDDAGVPP 452
Cdd:COG3598 216 dNGGRLALEEVAALTAGAGEVELKELVGGV 245
|
|
| 41 |
PHA02542 |
41 helicase; Provisional |
186-420 |
1.40e-06 |
|
41 helicase; Provisional
Pssm-ID: 222864 [Multi-domain] Cd Length: 473 Bit Score: 50.45 E-value: 1.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 186 IPTGFSELDRMT-AGFQRNDLIIVAARPSVGKTAFALNIAQNVATkTDESVAIFSLEMGSEQLVMRMLCAEGNINAQNLR 264
Cdd:PHA02542 172 IPFKLEILNKITkGGAERKTLNVLLAGVNVGKSLGLCSLAADYLQ-QGYNVLYISMEMAEEVIAKRIDANLLDVSLDDID 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 265 tgNLTEEDWgKLTMAMGSLSNSG-IFIDDTP--GIRVSEIRSKCRRLKQENGL--GMILIDYLQlIQGSGR---SSDNRQ 336
Cdd:PHA02542 251 --DLSKAEY-KAKMEKLRSKTQGkLIIKQYPtgGAHAGHFRALLNELKLKKNFkpDVIIVDYLG-ICASSRlrvSSENSY 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 337 QEVSEISRALKSLARELEVPVIALSQLSRGVEQRQDkrPMMSDIRESGSIEQDAD-IVAFLYRDD--------------- 400
Cdd:PHA02542 327 TYVKAIAEELRGLAVEHDVVVWTAAQTTRSGWDSSD--VDMSDTAESAGLPATADfMLAVIETEElaqmgqqlvkqlksr 404
|
250 260
....*....|....*....|
gi 500861317 401 YYDKESENKNIIEIIIAKQR 420
Cdd:PHA02542 405 YGDKNKFNKFLMGVDKGNQR 424
|
|
| KaiC-like |
cd01124 |
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ... |
186-364 |
7.56e-06 |
|
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410869 [Multi-domain] Cd Length: 222 Bit Score: 46.87 E-value: 7.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 186 IPTGFSELDRMT-AGFQRNDLIIVAARPSVGKTAFALNIAQNvATKTDESVAIFSLEMGSEQLVMRMLCAEGNINAqnlr 264
Cdd:cd01124 1 VKTGIPGLDELLgGGIPKGSVTLLTGGPGTGKTLFGLQFLYA-GAKNGEPGLFFTFEESPERLLRNAKSFGWDFDE---- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 265 tgnltEEDWGKLtmamgslsnsgIFIDDTP----GIRVSEIRSKCRRLKQENGLGMILIDYLQLIQgsgRSSDNRQQEVs 340
Cdd:cd01124 76 -----MEDEGKL-----------IIVDAPPteagRFSLDELLSRILSIIKSFKAKRVVIDSLSGLR---RAKEDQMRAR- 135
|
170 180
....*....|....*....|....
gi 500861317 341 EISRALKSLARELEVPVIALSQLS 364
Cdd:cd01124 136 RIVIALLNELRAAGVTTIFTSEMR 159
|
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
205-366 |
7.84e-06 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 46.61 E-value: 7.84e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 205 LIIVAARPSVGKTAFALNIAQNVATKTDE----------SVAIFSLEMGSEQLVMRMLCAEGNINAQnlrtGNLTEEDWG 274
Cdd:pfam13481 35 LGLLAGAPGTGKTTLALDLAAAVATGKPWlggprvpeqgKVLYVSAEGPADELRRRLRAAGADLDLP----ARLLFLSLV 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 275 KLTMamgslsnsgIFIDDTPGIRV-SEIRSKCRRLKQENGLGMILIDYLQLIQGsgrSSDNRQQEVSEISRALKSLAREL 353
Cdd:pfam13481 111 ESLP---------LFFLDRGGPLLdADVDALEAALEEVEDPDLVVIDPLARALG---GDENSNSDVGRLVKALDRLARRT 178
|
170
....*....|...
gi 500861317 354 EVPVIALSQLSRG 366
Cdd:pfam13481 179 GATVLLVHHVGKD 191
|
|
| KaiC_C |
cd19484 |
C-terminal domain of Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most ... |
186-251 |
1.28e-03 |
|
C-terminal domain of Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410892 [Multi-domain] Cd Length: 218 Bit Score: 40.00 E-value: 1.28e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 500861317 186 IPTGFSELDRMTA--GFQRNDLIIVAARPSVGKTAFALNIAQNvATKTDESVAIFSLEMGSEQLVMRM 251
Cdd:cd19484 1 ISTGIPRLDAMLGggGFFRGSSILVSGATGTGKTLLAASFADA-ACRRGERCLYFAFEESPAQLIRNA 67
|
|
| RecA-like_superfamily |
cd01120 |
RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 ... |
298-387 |
2.58e-03 |
|
RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410865 [Multi-domain] Cd Length: 119 Bit Score: 37.87 E-value: 2.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500861317 298 VSEIRSKCRRLKQENGLGMILIDYLQLIqgSGRSSDNRQQEVSEISRALKSLARELEVPVIALSQLSRGVEqrqDKRPMM 377
Cdd:cd01120 35 LDTILEAIEDLIEEKKLDIIIIDSLSSL--ARASQGDRSSELLEDLAKLLRAARNTGITVIATIHSDKFDI---DRGGSS 109
|
90
....*....|
gi 500861317 378 SDIRESGSIE 387
Cdd:cd01120 110 NDERLLKSLR 119
|
|
| PRK09302 |
PRK09302 |
circadian clock protein KaiC; Reviewed |
186-251 |
8.27e-03 |
|
circadian clock protein KaiC; Reviewed
Pssm-ID: 236461 [Multi-domain] Cd Length: 509 Bit Score: 38.32 E-value: 8.27e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 500861317 186 IPTGFSELDRMTA-GFQRNDLIIVAARPSVGKTAFALNIAQNvATKTDESVAIFSLEMGSEQLVMRM 251
Cdd:PRK09302 255 ISSGVPDLDEMLGgGFFRGSIILVSGATGTGKTLLASKFAEA-ACRRGERCLLFAFEESRAQLIRNA 320
|
|
| |
