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Conserved domains on  [gi|500858568|ref|WP_012010072|]
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MULTISPECIES: DUF3992 domain-containing protein [Bacillus]

Protein Classification

DUF3992 domain-containing protein( domain architecture ID 10587019)

DUF3992 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Enas pfam13157
Endospore appendages; The surface of Bacillus and Clostridium endospores is decorated with ...
 4-114 3.49e-25

Endospore appendages; The surface of Bacillus and Clostridium endospores is decorated with long filamentous endospores appendages that resemble pili from Gram- negative and Gram-positive bacteria. They show two morphologies, the main or Staggered-type (S-Ena) which accounts for 90% of the fibres, and the Ladder-like (L-Ena) which is smaller and less abundant. They are a novel class of Gram-positive pili, consisting in single domain subunits with a jellyroll topology comprised by two juxtaposed beta-sheets. This domain represents the S-Ena core. Disulfide bonding through the N-terminal connector peptide that precedes this domain stabilizes longitudinally the fibres, bridging the helical turns. This results in flexible pili, highly resistant to environmental harsh such as heat, drought, and chemical damage.


:

Pssm-ID: 463794  Cd Length: 111  Bit Score: 91.17  E-value: 3.49e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500858568    4 LGGCSNEQTgFVNDAVCFTVDLAAAADPV-VVWTDGTPFVINGTIMVENNGIVAvAPTVTLEVNGAAVPDFTVAPGESQS 82
Cdd:pfam13157   1 LGCCPDKKE-IVQDKVCGNFSITCGGKGTtTLWTNNTNQNISGTIYVKNEGGCG-AITVDVLVNGGTVKTFTLPPGESRS 78

                          90       100       110
                  ....*....|....*....|....*....|...
gi 500858568   83 ITLSDLNSIGIVATGGT-STGSIVVSFSLNYQY 114
Cdd:pfam13157  79 FTVSRLDSIEIVCTGAAdGTCQGEFCITLHYKL 111
 
Name Accession Description Interval E-value
Enas pfam13157
Endospore appendages; The surface of Bacillus and Clostridium endospores is decorated with ...
 4-114 3.49e-25

Endospore appendages; The surface of Bacillus and Clostridium endospores is decorated with long filamentous endospores appendages that resemble pili from Gram- negative and Gram-positive bacteria. They show two morphologies, the main or Staggered-type (S-Ena) which accounts for 90% of the fibres, and the Ladder-like (L-Ena) which is smaller and less abundant. They are a novel class of Gram-positive pili, consisting in single domain subunits with a jellyroll topology comprised by two juxtaposed beta-sheets. This domain represents the S-Ena core. Disulfide bonding through the N-terminal connector peptide that precedes this domain stabilizes longitudinally the fibres, bridging the helical turns. This results in flexible pili, highly resistant to environmental harsh such as heat, drought, and chemical damage.


Pssm-ID: 463794  Cd Length: 111  Bit Score: 91.17  E-value: 3.49e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500858568    4 LGGCSNEQTgFVNDAVCFTVDLAAAADPV-VVWTDGTPFVINGTIMVENNGIVAvAPTVTLEVNGAAVPDFTVAPGESQS 82
Cdd:pfam13157   1 LGCCPDKKE-IVQDKVCGNFSITCGGKGTtTLWTNNTNQNISGTIYVKNEGGCG-AITVDVLVNGGTVKTFTLPPGESRS 78

                          90       100       110
                  ....*....|....*....|....*....|...
gi 500858568   83 ITLSDLNSIGIVATGGT-STGSIVVSFSLNYQY 114
Cdd:pfam13157  79 FTVSRLDSIEIVCTGAAdGTCQGEFCITLHYKL 111
 
Name Accession Description Interval E-value
Enas pfam13157
Endospore appendages; The surface of Bacillus and Clostridium endospores is decorated with ...
 4-114 3.49e-25

Endospore appendages; The surface of Bacillus and Clostridium endospores is decorated with long filamentous endospores appendages that resemble pili from Gram- negative and Gram-positive bacteria. They show two morphologies, the main or Staggered-type (S-Ena) which accounts for 90% of the fibres, and the Ladder-like (L-Ena) which is smaller and less abundant. They are a novel class of Gram-positive pili, consisting in single domain subunits with a jellyroll topology comprised by two juxtaposed beta-sheets. This domain represents the S-Ena core. Disulfide bonding through the N-terminal connector peptide that precedes this domain stabilizes longitudinally the fibres, bridging the helical turns. This results in flexible pili, highly resistant to environmental harsh such as heat, drought, and chemical damage.


Pssm-ID: 463794  Cd Length: 111  Bit Score: 91.17  E-value: 3.49e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500858568    4 LGGCSNEQTgFVNDAVCFTVDLAAAADPV-VVWTDGTPFVINGTIMVENNGIVAvAPTVTLEVNGAAVPDFTVAPGESQS 82
Cdd:pfam13157   1 LGCCPDKKE-IVQDKVCGNFSITCGGKGTtTLWTNNTNQNISGTIYVKNEGGCG-AITVDVLVNGGTVKTFTLPPGESRS 78

                          90       100       110
                  ....*....|....*....|....*....|...
gi 500858568   83 ITLSDLNSIGIVATGGT-STGSIVVSFSLNYQY 114
Cdd:pfam13157  79 FTVSRLDSIEIVCTGAAdGTCQGEFCITLHYKL 111
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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