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Conserved domains on  [gi|500664873|ref|WP_011969204|]
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MULTISPECIES: FAD-dependent oxidoreductase [Clostridium]

Protein Classification

FAD-dependent oxidoreductase( domain architecture ID 12014393)

FAD-dependent oxidoreductase similar to tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG that is involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GIDA pfam01134
Glucose inhibited division protein A;
2-352 4.86e-53

Glucose inhibited division protein A;


:

Pssm-ID: 250388 [Multi-domain]  Cd Length: 391  Bit Score: 181.98  E-value: 4.86e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873    2 KVIIVGGGWSGCAAAISSKKAGADVTII-EKTDLLLGLGNVGGImRNNGRYTAAEELIALgGGDLIKITDEISTHKNID- 79
Cdd:pfam01134   1 DVIVIGGGHAGCEAALAAARMGAKVLLItHNTDTIAELSCNPSI-GGIAKGHLVREIDAL-GGLMGKAADKTGIQFRMLn 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873   80 ----FPGHKHATLYNVNLIEGVVSKYLKSLDiNL-MMESRVNDINFDGQKIKGAYLSDGTYIEGDVFIETTGTtgpmgnc 154
Cdd:pfam01134  79 tskgPAVRALRAQVDRDLYSKEMTETLENHP-NLtLIQGEVTDLIPENGKVKGVVTEDGEEYKAKAVVLATGT------- 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873  155 lrYGNGCSMCVLRCPAFGPRISISERCGVSDIQgERGDDiLGAFSGSCKLAKESLSDEIRNEL----DSKGVV------- 223
Cdd:pfam01134 151 --FLNGKIHIGLKCYPAGRLGELTSEGLSESLK-ELGFE-LGRFKTGTPPRIDKDSIDFSKLEeqpgDKPGPPfsylncp 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873  224 ----------------VLKVPKEDIN--------YDKLSTKVC-----QQYALKEFAENIILL-------DTGHAKLMTT 267
Cdd:pfam01134 227 mnkeqypcfltytneaTHEIIRDNLHrspmfegcIEGIGPRYCpsiedKPVRFADKPYHQVFLepegldtDEYYLVGFST 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873  268 YYPLYK----LRKIKGLENAKYVDPyagskGNSIRYLSVAPRT--NDLKVIGVDNLFCAGEKSGLfVGHTEAMCTGALAG 341
Cdd:pfam01134 307 SLPEDVqkrvLRTIPGLENAEIVRP-----GYAIEYDYIDPPQllPTLETKKIPGLFFAGQINGT-EGYEEAAAQGLLAG 380

                         410
                  ....*....|.
gi 500664873  342 HNAVRLAMGMP 352
Cdd:pfam01134 381 INAARKALGKE 391
 
Name Accession Description Interval E-value
GIDA pfam01134
Glucose inhibited division protein A;
2-352 4.86e-53

Glucose inhibited division protein A;


Pssm-ID: 250388 [Multi-domain]  Cd Length: 391  Bit Score: 181.98  E-value: 4.86e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873    2 KVIIVGGGWSGCAAAISSKKAGADVTII-EKTDLLLGLGNVGGImRNNGRYTAAEELIALgGGDLIKITDEISTHKNID- 79
Cdd:pfam01134   1 DVIVIGGGHAGCEAALAAARMGAKVLLItHNTDTIAELSCNPSI-GGIAKGHLVREIDAL-GGLMGKAADKTGIQFRMLn 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873   80 ----FPGHKHATLYNVNLIEGVVSKYLKSLDiNL-MMESRVNDINFDGQKIKGAYLSDGTYIEGDVFIETTGTtgpmgnc 154
Cdd:pfam01134  79 tskgPAVRALRAQVDRDLYSKEMTETLENHP-NLtLIQGEVTDLIPENGKVKGVVTEDGEEYKAKAVVLATGT------- 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873  155 lrYGNGCSMCVLRCPAFGPRISISERCGVSDIQgERGDDiLGAFSGSCKLAKESLSDEIRNEL----DSKGVV------- 223
Cdd:pfam01134 151 --FLNGKIHIGLKCYPAGRLGELTSEGLSESLK-ELGFE-LGRFKTGTPPRIDKDSIDFSKLEeqpgDKPGPPfsylncp 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873  224 ----------------VLKVPKEDIN--------YDKLSTKVC-----QQYALKEFAENIILL-------DTGHAKLMTT 267
Cdd:pfam01134 227 mnkeqypcfltytneaTHEIIRDNLHrspmfegcIEGIGPRYCpsiedKPVRFADKPYHQVFLepegldtDEYYLVGFST 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873  268 YYPLYK----LRKIKGLENAKYVDPyagskGNSIRYLSVAPRT--NDLKVIGVDNLFCAGEKSGLfVGHTEAMCTGALAG 341
Cdd:pfam01134 307 SLPEDVqkrvLRTIPGLENAEIVRP-----GYAIEYDYIDPPQllPTLETKKIPGLFFAGQINGT-EGYEEAAAQGLLAG 380

                         410
                  ....*....|.
gi 500664873  342 HNAVRLAMGMP 352
Cdd:pfam01134 381 INAARKALGKE 391
TrmFO COG1206
Folate-dependent tRNA-U54 methylase TrmFO/GidA [Translation, ribosomal structure and ...
 274-368 4.92e-09

Folate-dependent tRNA-U54 methylase TrmFO/GidA [Translation, ribosomal structure and biogenesis]; Folate-dependent tRNA-U54 methylase TrmFO/GidA is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440819  Cd Length: 436  Bit Score: 57.76  E-value: 4.92e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873 274 LRKIKGLENAKYVdpyagskgnsiRYLSV-------APR--TNDLKVIGVDNLFCAGEKSGlfV-GHTEAMCTGALAGHN 343
Cdd:COG1206  292 FRMIPGLENAEFV-----------RYGVMhrntfinSPKllDPTLQLKARPNLFFAGQITG--VeGYVESAASGLLAGIN 358

                         90       100
                 ....*....|....*....|....*
gi 500664873 344 AVRLAMGMPLLILPSSIAIGDMITY 368
Cdd:COG1206  359 AARLLLGKEPVPPPPTTALGALLNY 383
PRK05335 PRK05335
tRNA (uracil-5-)-methyltransferase Gid; Reviewed
 274-368 2.63e-08

tRNA (uracil-5-)-methyltransferase Gid; Reviewed


Pssm-ID: 235416  Cd Length: 436  Bit Score: 55.54  E-value: 2.63e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873 274 LRKIKGLENAKYVdpyagskgnsiRYLSV-------APR--TNDLKVIGVDNLFCAGEKSGlfV-GHTEAMCTGALAGHN 343
Cdd:PRK05335 292 FRMIPGLENAEFV-----------RYGVMhrntfinSPKllDPTLQLKKRPNLFFAGQITG--VeGYVESAASGLLAGIN 358

                         90       100
                 ....*....|....*....|....*
gi 500664873 344 AVRLAMGMPLLILPSSIAIGDMITY 368
Cdd:PRK05335 359 AARLALGKEPVIPPPTTALGALLNY 383
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 3-33 1.07e-03

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 40.77  E-value: 1.07e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 500664873    3 VIIVGGGWSGCAAAISSKKAGADVTIIEKTD 33
Cdd:TIGR02032   3 VVVVGAGPAGASAAYRLADKGLRVLLLEKKS 33
 
Name Accession Description Interval E-value
GIDA pfam01134
Glucose inhibited division protein A;
2-352 4.86e-53

Glucose inhibited division protein A;


Pssm-ID: 250388 [Multi-domain]  Cd Length: 391  Bit Score: 181.98  E-value: 4.86e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873    2 KVIIVGGGWSGCAAAISSKKAGADVTII-EKTDLLLGLGNVGGImRNNGRYTAAEELIALgGGDLIKITDEISTHKNID- 79
Cdd:pfam01134   1 DVIVIGGGHAGCEAALAAARMGAKVLLItHNTDTIAELSCNPSI-GGIAKGHLVREIDAL-GGLMGKAADKTGIQFRMLn 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873   80 ----FPGHKHATLYNVNLIEGVVSKYLKSLDiNL-MMESRVNDINFDGQKIKGAYLSDGTYIEGDVFIETTGTtgpmgnc 154
Cdd:pfam01134  79 tskgPAVRALRAQVDRDLYSKEMTETLENHP-NLtLIQGEVTDLIPENGKVKGVVTEDGEEYKAKAVVLATGT------- 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873  155 lrYGNGCSMCVLRCPAFGPRISISERCGVSDIQgERGDDiLGAFSGSCKLAKESLSDEIRNEL----DSKGVV------- 223
Cdd:pfam01134 151 --FLNGKIHIGLKCYPAGRLGELTSEGLSESLK-ELGFE-LGRFKTGTPPRIDKDSIDFSKLEeqpgDKPGPPfsylncp 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873  224 ----------------VLKVPKEDIN--------YDKLSTKVC-----QQYALKEFAENIILL-------DTGHAKLMTT 267
Cdd:pfam01134 227 mnkeqypcfltytneaTHEIIRDNLHrspmfegcIEGIGPRYCpsiedKPVRFADKPYHQVFLepegldtDEYYLVGFST 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873  268 YYPLYK----LRKIKGLENAKYVDPyagskGNSIRYLSVAPRT--NDLKVIGVDNLFCAGEKSGLfVGHTEAMCTGALAG 341
Cdd:pfam01134 307 SLPEDVqkrvLRTIPGLENAEIVRP-----GYAIEYDYIDPPQllPTLETKKIPGLFFAGQINGT-EGYEEAAAQGLLAG 380

                         410
                  ....*....|.
gi 500664873  342 HNAVRLAMGMP 352
Cdd:pfam01134 381 INAARKALGKE 391
TrmFO COG1206
Folate-dependent tRNA-U54 methylase TrmFO/GidA [Translation, ribosomal structure and ...
 274-368 4.92e-09

Folate-dependent tRNA-U54 methylase TrmFO/GidA [Translation, ribosomal structure and biogenesis]; Folate-dependent tRNA-U54 methylase TrmFO/GidA is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440819  Cd Length: 436  Bit Score: 57.76  E-value: 4.92e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873 274 LRKIKGLENAKYVdpyagskgnsiRYLSV-------APR--TNDLKVIGVDNLFCAGEKSGlfV-GHTEAMCTGALAGHN 343
Cdd:COG1206  292 FRMIPGLENAEFV-----------RYGVMhrntfinSPKllDPTLQLKARPNLFFAGQITG--VeGYVESAASGLLAGIN 358

                         90       100
                 ....*....|....*....|....*
gi 500664873 344 AVRLAMGMPLLILPSSIAIGDMITY 368
Cdd:COG1206  359 AARLLLGKEPVPPPPTTALGALLNY 383
PRK05335 PRK05335
tRNA (uracil-5-)-methyltransferase Gid; Reviewed
 274-368 2.63e-08

tRNA (uracil-5-)-methyltransferase Gid; Reviewed


Pssm-ID: 235416  Cd Length: 436  Bit Score: 55.54  E-value: 2.63e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873 274 LRKIKGLENAKYVdpyagskgnsiRYLSV-------APR--TNDLKVIGVDNLFCAGEKSGlfV-GHTEAMCTGALAGHN 343
Cdd:PRK05335 292 FRMIPGLENAEFV-----------RYGVMhrntfinSPKllDPTLQLKKRPNLFFAGQITG--VeGYVESAASGLLAGIN 358

                         90       100
                 ....*....|....*....|....*
gi 500664873 344 AVRLAMGMPLLILPSSIAIGDMITY 368
Cdd:PRK05335 359 AARLALGKEPVIPPPTTALGALLNY 383
FAD_oxidored pfam12831
FAD dependent oxidoreductase; This family of proteins contains FAD dependent oxidoreductases ...
 3-146 1.14e-06

FAD dependent oxidoreductase; This family of proteins contains FAD dependent oxidoreductases and related proteins.


Pssm-ID: 432816 [Multi-domain]  Cd Length: 420  Bit Score: 50.30  E-value: 1.14e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873    3 VIIVGGGWSGCAAAISSKKAGADVTIIEKTDL---LLGLGNVGGIMrnnGRYTAAEELIalGGgdlikITDEIstHKNID 79
Cdd:pfam12831   2 VVVVGGGPAGVAAAIAAARAGAKVLLVERRGFlggMLTSGLVGPDM---GFYLNKEQVV--GG-----IAREF--RQRLR 69

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 500664873   80 FPGHKHATL---YNVNLIEGVVSKY-----LKSLDINLMMESRVNDINFDGQKIKGAYL---SDGTYIEGDVFIETTG 146
Cdd:pfam12831  70 ARGGLPGPYglrGGWVPFDPEVAKAvldemLAEAGVTVLLHTRVVGVVKEGGRITGVTVetkGGRITIRAKVFIDATG 147
MnmG COG0445
tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA [Translation, ribosomal ...
 274-366 7.30e-06

tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA [Translation, ribosomal structure and biogenesis]; tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440214 [Multi-domain]  Cd Length: 626  Bit Score: 48.08  E-value: 7.30e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873 274 LRKIKGLENAKYVDP-YAgskgnsIRYLSVAPR--TNDLKVIGVDNLFCAGEKSGlfvghT----EAMCTGALAGHNAVR 346
Cdd:COG0445  324 LRSIPGLENAEILRPgYA------IEYDYVDPTqlKPTLETKKIEGLFFAGQING-----TtgyeEAAAQGLMAGINAAL 392

                         90       100
                 ....*....|....*....|.
gi 500664873 347 LAMGMPLLILPSSIA-IGDMI 366
Cdd:COG0445  393 KAQGKEPFILDRSEAyIGVLI 413
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 3-33 1.58e-05

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 46.75  E-value: 1.58e-05
                         10        20        30
                 ....*....|....*....|....*....|.
gi 500664873   3 VIIVGGGWSGCAAAISSKKAGADVTIIEKTD 33
Cdd:COG1053    6 VVVVGSGGAGLRAALEAAEAGLKVLVLEKVP 36
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 1-142 2.00e-05

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 46.08  E-value: 2.00e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873   1 MKVIIVGGGWSGCAAAISSKKAGADVTIIEKTDLLLGLGNVGGIMRNngrytAAEELIALGGGDLIK----ITDEISTH- 75
Cdd:COG0654    4 TDVLIVGGGPAGLALALALARAGIRVTVVERAPPPRPDGRGIALSPR-----SLELLRRLGLWDRLLargaPIRGIRVRd 78

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 500664873  76 -------KNIDFPGHKHATLYNV--NLIEGVVSKYLKSLDINLMMESRVNDINFDGQKIkGAYLSDGTYIEGDVFI 142
Cdd:COG0654   79 gsdgrvlARFDAAETGLPAGLVVprADLERALLEAARALGVELRFGTEVTGLEQDADGV-TVTLADGRTLRADLVV 153
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 1-30 5.62e-05

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 45.23  E-value: 5.62e-05
                         10        20        30
                 ....*....|....*....|....*....|
gi 500664873   1 MKVIIVGGGWSGCAAAISSKKAGADVTIIE 30
Cdd:COG3349    4 PRVVVVGGGLAGLAAAVELAEAGFRVTLLE 33
FAD_binding_2 pfam00890
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 3-32 6.08e-05

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


Pssm-ID: 395718 [Multi-domain]  Cd Length: 398  Bit Score: 44.97  E-value: 6.08e-05
                          10        20        30
                  ....*....|....*....|....*....|
gi 500664873    3 VIIVGGGWSGCAAAISSKKAGADVTIIEKT 32
Cdd:pfam00890   2 VLVIGGGLAGLAAALAAAEAGLKVAVVEKG 31
PRK06847 PRK06847
hypothetical protein; Provisional
 2-31 6.74e-05

hypothetical protein; Provisional


Pssm-ID: 235874 [Multi-domain]  Cd Length: 375  Bit Score: 44.86  E-value: 6.74e-05
                         10        20        30
                 ....*....|....*....|....*....|
gi 500664873   2 KVIIVGGGWSGCAAAISSKKAGADVTIIEK 31
Cdd:PRK06847   6 KVLIVGGGIGGLSAAIALRRAGIAVDLVEI 35
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
5-33 9.63e-05

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 40.21  E-value: 9.63e-05
                          10        20
                  ....*....|....*....|....*....
gi 500664873    5 IVGGGWSGCAAAISSKKAGADVTIIEKTD 33
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRD 29
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
1-31 1.84e-04

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 43.36  E-value: 1.84e-04
                         10        20        30
                 ....*....|....*....|....*....|.
gi 500664873   1 MKVIIVGGGWSGCAAAISSKKAGADVTIIEK 31
Cdd:COG0665    3 ADVVVIGGGIAGLSTAYHLARRGLDVTVLER 33
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 1-30 2.03e-04

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 43.08  E-value: 2.03e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 500664873    1 MKVIIVGGGWSGCAAAISSKKAGADVTIIE 30
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGGKVTLIE 30
HI0933_like pfam03486
HI0933-like protein;
2-31 2.15e-04

HI0933-like protein;


Pssm-ID: 427330 [Multi-domain]  Cd Length: 406  Bit Score: 43.34  E-value: 2.15e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 500664873    2 KVIIVGGGWSGCAAAISSKKAGADVTIIEK 31
Cdd:pfam03486   2 DVIVIGGGAAGLMAAISAAKRGRRVLLIEK 31
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
2-33 3.90e-04

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 42.54  E-value: 3.90e-04
                         10        20        30
                 ....*....|....*....|....*....|..
gi 500664873   2 KVIIVGGGWSGCAAAISSKKAGADVTIIEKTD 33
Cdd:COG1148  142 RALVIGGGIAGMTAALELAEQGYEVYLVEKEP 173
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 1-33 5.21e-04

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 42.13  E-value: 5.21e-04
                         10        20        30
                 ....*....|....*....|....*....|...
gi 500664873   1 MKVIIVGGGWSGCAAAISSKKAGADVTIIEKTD 33
Cdd:COG1232    2 KRVAVIGGGIAGLTAAYRLAKAGHEVTVLEASD 34
PTZ00306 PTZ00306
NADH-dependent fumarate reductase; Provisional
 2-31 5.90e-04

NADH-dependent fumarate reductase; Provisional


Pssm-ID: 140327 [Multi-domain]  Cd Length: 1167  Bit Score: 42.46  E-value: 5.90e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 500664873    2 KVIIVGGGWSGCAAAISSKKAGADVTIIEK 31
Cdd:PTZ00306  411 RVIVVGGGLAGCSAAIEAASCGAQVILLEK 440
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 3-33 7.69e-04

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 41.39  E-value: 7.69e-04
                         10        20        30
                 ....*....|....*....|....*....|.
gi 500664873   3 VIIVGGGWSGCAAAISSKKAGADVTIIEKTD 33
Cdd:COG2072    9 VVVIGAGQAGLAAAYHLRRAGIDFVVLEKAD 39
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 2-146 8.66e-04

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 41.15  E-value: 8.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873    2 KVIIVGGGWSGCAAAISSKKAGADVTIIEKTDLllglgnvggimrnngrytaaeeliaLGGGDLIKITDEisthknidfp 81
Cdd:pfam07992 154 RVVVVGGGYIGVELAAALAKLGKEVTLIEALDR-------------------------LLRAFDEEISAA---------- 198

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 500664873   82 ghkhatlynvnliegvVSKYLKSLDINLMMESRVNDINFDGQKIKGAyLSDGTYIEGDVFIETTG 146
Cdd:pfam07992 199 ----------------LEKALEKNGVEVRLGTSVKEIIGDGDGVEVI-LKDGTEIDADLVVVAIG 246
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 2-31 1.02e-03

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 40.84  E-value: 1.02e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 500664873    2 KVIIVGGGWSGCAAAISSKKAGADVTIIEK 31
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLER 30
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 3-33 1.07e-03

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 40.77  E-value: 1.07e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 500664873    3 VIIVGGGWSGCAAAISSKKAGADVTIIEKTD 33
Cdd:TIGR02032   3 VVVVGAGPAGASAAYRLADKGLRVLLLEKKS 33
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 1-33 1.32e-03

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 40.99  E-value: 1.32e-03
                         10        20        30
                 ....*....|....*....|....*....|...
gi 500664873   1 MKVIIVGGGWSGCAAAISSKKAGADVTIIEKTD 33
Cdd:COG1233    4 YDVVVIGAGIGGLAAAALLARAGYRVTVLEKND 36
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 2-33 2.40e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 36.80  E-value: 2.40e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 500664873    2 KVIIVGGGWSGCAAAISSKKAGADVTIIEKTD 33
Cdd:pfam00070   1 RVVVVGGGYIGLELAGALARLGSKVTVVERRD 32
PRK11883 PRK11883
protoporphyrinogen oxidase; Reviewed
 1-33 2.44e-03

protoporphyrinogen oxidase; Reviewed


Pssm-ID: 237009 [Multi-domain]  Cd Length: 451  Bit Score: 39.83  E-value: 2.44e-03
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 500664873   1 MKVIIVGGGWSGCAAAISSKKAG--ADVTIIEKTD 33
Cdd:PRK11883   1 KKVAIIGGGITGLSAAYRLHKKGpdADITLLEASD 35
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
8-152 2.48e-03

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 39.57  E-value: 2.48e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500664873   8 GGWSGCAAAISSKKAGADVTIIEKTDLLLGLGNVGGIMRNngrytAAEELIALGGGDLikITDEIsTHKNIDFPGHKHAT 87
Cdd:COG0644    1 AGPAGSAAARRLARAGLSVLLLEKGSFPGDKICGGGLLPR-----ALEELEPLGLDEP--LERPV-RGARFYSPGGKSVE 72

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 500664873  88 L-------YNVNLieGVVSKYL----KSLDINLMMESRVNDINFDGQKIKgAYLSDGTYIEGDVFIETTGTTGPMG 152
Cdd:COG0644   73 LppgrgggYVVDR--ARFDRWLaeqaEEAGAEVRTGTRVTDVLRDDGRVV-VRTGDGEEIRADYVVDADGARSLLA 145
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 3-31 2.53e-03

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 40.07  E-value: 2.53e-03
                         10        20
                 ....*....|....*....|....*....
gi 500664873   3 VIIVGGGWSGCAAAISSKKAGADVTIIEK 31
Cdd:COG1249    6 LVVIGAGPGGYVAAIRAAQLGLKVALVEK 34
PRK06753 PRK06753
hypothetical protein; Provisional
 1-31 2.96e-03

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 39.67  E-value: 2.96e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 500664873   1 MKVIIVGGGWSGCAAAISSKKAGADVTIIEK 31
Cdd:PRK06753   1 MKIAIIGAGIGGLTAAALLQEQGHEVKVFEK 31
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
2-30 4.19e-03

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 39.13  E-value: 4.19e-03
                         10        20
                 ....*....|....*....|....*....
gi 500664873   2 KVIIVGGGWSGCAAAISSKKAGADVTIIE 30
Cdd:COG1231    9 DVVIVGAGLAGLAAARELRKAGLDVTVLE 37
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 2-31 4.39e-03

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 39.44  E-value: 4.39e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 500664873   2 KVIIVGGGWSGCAAAISSKKAGADVTIIEK 31
Cdd:PRK01747 262 DAAIIGGGIAGAALALALARRGWQVTLYEA 291
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
2-31 5.06e-03

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 38.56  E-value: 5.06e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 500664873   2 KVIIVGGGWSGCAAAISSKKAGADVTIIEK 31
Cdd:COG0492    2 DVVIIGAGPAGLTAAIYAARAGLKTLVIEG 31
PRK12842 PRK12842
putative succinate dehydrogenase; Reviewed
 3-33 8.92e-03

putative succinate dehydrogenase; Reviewed


Pssm-ID: 237224 [Multi-domain]  Cd Length: 574  Bit Score: 38.14  E-value: 8.92e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 500664873   3 VIIVGGGWSGCAAAISSKKAGADVTIIEKTD 33
Cdd:PRK12842  12 VLVIGSGAGGLSAAITARKLGLDVVVLEKEP 42
PRK05329 PRK05329
glycerol-3-phosphate dehydrogenase subunit GlpB;
1-29 9.73e-03

glycerol-3-phosphate dehydrogenase subunit GlpB;


Pssm-ID: 235412  Cd Length: 422  Bit Score: 37.91  E-value: 9.73e-03
                         10        20
                 ....*....|....*....|....*....
gi 500664873   1 MKVIIVGGGWSGCAAAISSKKAGADVTII 29
Cdd:PRK05329   3 FDVLVIGGGLAGLTAALAAAEAGKRVALV 31
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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