NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|499973115|ref|WP_011653833|]
View 

MULTISPECIES: ABC transporter permease [Rhizobium]

Protein Classification

ABC transporter permease( domain architecture ID 11427312)

ABC transporter permease similar to ABC oligopeptide transporter permease proteins (OppB, AppB, and AmiC), the transmembrane subunits (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Gene Ontology:  GO:0055085
PubMed:  18535149|17723295
TCDB:  3.A.1

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 19-328 3.93e-106

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 312.77  E-value: 3.93e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115  19 LKAVGVRLLAGIPVFLLVTFSATALSSLMPGSAAQLILGENATQAQIDALNSRYGYDLPVWERYLGWLGRLLQGDLGQTM 98
Cdd:COG0601    2 LRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTSF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115  99 FSQQSVAKLLVDRAAVTFEIALLAMFVSLLIGLPLAMYTASRPGGIEDTVLRAVSSVMLSIPTFVIVVLLGFVFAIVLRW 178
Cdd:COG0601   82 VYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGW 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 179 LPATGWVSFSDDPIGNLYYVALPVMCLSVHQAAYFYRVSRSEFVAILQEDYVLVARAKGLPTRYILMRHVLRPASPQVLT 258
Cdd:COG0601  162 LPVSGRVSPWEDFLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVT 241

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 259 VMGLSMTYLLGGSFIVESYFAVPGIGWTVLNAVSSHDLPVMQAILSLTVVIFVVIFILVDLGYALIDPRV 328
Cdd:COG0601  242 VLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRI 311
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 19-328 3.93e-106

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 312.77  E-value: 3.93e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115  19 LKAVGVRLLAGIPVFLLVTFSATALSSLMPGSAAQLILGENATQAQIDALNSRYGYDLPVWERYLGWLGRLLQGDLGQTM 98
Cdd:COG0601    2 LRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTSF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115  99 FSQQSVAKLLVDRAAVTFEIALLAMFVSLLIGLPLAMYTASRPGGIEDTVLRAVSSVMLSIPTFVIVVLLGFVFAIVLRW 178
Cdd:COG0601   82 VYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGW 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 179 LPATGWVSFSDDPIGNLYYVALPVMCLSVHQAAYFYRVSRSEFVAILQEDYVLVARAKGLPTRYILMRHVLRPASPQVLT 258
Cdd:COG0601  162 LPVSGRVSPWEDFLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVT 241

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 259 VMGLSMTYLLGGSFIVESYFAVPGIGWTVLNAVSSHDLPVMQAILSLTVVIFVVIFILVDLGYALIDPRV 328
Cdd:COG0601  242 VLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRI 311
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 25-328 2.54e-47

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 161.81  E-value: 2.54e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115  25 RLLAGIPVFLLVTFSATALSSLMPGSAAQLILGENATQAQIDALNSRYGYDLPVWERYLGWLGRLLQGDLGQTMFSQQSV 104
Cdd:PRK15081   8 RLLGLIPTLLIVAVLVFLFVHLLPGDPARLAAGPEADAQVVALVRQQLGLDQPLPHQFWHYISNALQGDFGTSMVSRRPV 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 105 AKLLVDRAAVTFEIALLAMFVSLLIGLPLAMYTASRPGGIEDTVLRAVSSVMLSIPTFVIVVLLGFVFAIVLRWLPATGW 184
Cdd:PRK15081  88 SEEIASRFMPTLWLTITSMVWAVIFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMQVFSVELGWLPTVGA 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 185 VSFsddpignLYYVaLPVMCLSVHQAAYFYRVSRSEFVAILQEDYVLVARAKGLPTRYILMRHVLRPASPQVLTVMGLSM 264
Cdd:PRK15081 168 DSW-------QHYI-LPSLTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQF 239

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499973115 265 TYLLGGSFIVESYFAVPGIGWTVLNAVSSHDLPVMQAILSLTVVIFVVIFILVDLGYALIDPRV 328
Cdd:PRK15081 240 GFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLYAAINPAI 303
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 130-330 1.78e-20

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 86.97  E-value: 1.78e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115  130 GLPLAMYTASRPGGIEDTVLRAVSSVMLSIPTFVIVVLLgfvfaivlrwlpatgwvsFSDDPIGNLYYVALPVMCLSVHQ 209
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILL------------------VVIAILSILGHGILPAIILALLG 62

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115  210 AAYFYRVSRSEFVAILQEDYVLVARAKGLPTRYILMRHVLRPASPQVLTVMGLSMTYLLGGSFIVESYFAVPGIGWTVLN 289
Cdd:pfam00528  63 WAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIE 142

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 499973115  290 AVSSHDLPVMQAILSLTVVIFVVIFILVDLGYALIDPRVDV 330
Cdd:pfam00528 143 AILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVRK 183
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 112-316 7.06e-13

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 66.15  E-value: 7.06e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 112 AAVTFEIALLAMFVSLLIGLPLAMYTASRPGGIeDTVLRAVSSVMLSIPTFVIVVLLGFVFAIVLRWLPATGWvsfsddp 191
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKL-DRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGL------- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 192 ignlyyvALPVMCLSVHQAAYFYRVSRSEFVAILQEDYVLVARAKGLPTRYILMRHVLRPASPQVLTVMGLSMTYLLGGS 271
Cdd:cd06261   73 -------GLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEF 145

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 499973115 272 FIVESYFAVPGIGWTVLNAVSSHDLPVMQAILSLTVVIFVVIFIL 316
Cdd:cd06261  146 ALVSFLGGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 19-328 3.93e-106

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 312.77  E-value: 3.93e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115  19 LKAVGVRLLAGIPVFLLVTFSATALSSLMPGSAAQLILGENATQAQIDALNSRYGYDLPVWERYLGWLGRLLQGDLGQTM 98
Cdd:COG0601    2 LRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTSF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115  99 FSQQSVAKLLVDRAAVTFEIALLAMFVSLLIGLPLAMYTASRPGGIEDTVLRAVSSVMLSIPTFVIVVLLGFVFAIVLRW 178
Cdd:COG0601   82 VYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGW 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 179 LPATGWVSFSDDPIGNLYYVALPVMCLSVHQAAYFYRVSRSEFVAILQEDYVLVARAKGLPTRYILMRHVLRPASPQVLT 258
Cdd:COG0601  162 LPVSGRVSPWEDFLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVT 241

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 259 VMGLSMTYLLGGSFIVESYFAVPGIGWTVLNAVSSHDLPVMQAILSLTVVIFVVIFILVDLGYALIDPRV 328
Cdd:COG0601  242 VLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRI 311
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 25-328 2.54e-47

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 161.81  E-value: 2.54e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115  25 RLLAGIPVFLLVTFSATALSSLMPGSAAQLILGENATQAQIDALNSRYGYDLPVWERYLGWLGRLLQGDLGQTMFSQQSV 104
Cdd:PRK15081   8 RLLGLIPTLLIVAVLVFLFVHLLPGDPARLAAGPEADAQVVALVRQQLGLDQPLPHQFWHYISNALQGDFGTSMVSRRPV 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 105 AKLLVDRAAVTFEIALLAMFVSLLIGLPLAMYTASRPGGIEDTVLRAVSSVMLSIPTFVIVVLLGFVFAIVLRWLPATGW 184
Cdd:PRK15081  88 SEEIASRFMPTLWLTITSMVWAVIFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMQVFSVELGWLPTVGA 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 185 VSFsddpignLYYVaLPVMCLSVHQAAYFYRVSRSEFVAILQEDYVLVARAKGLPTRYILMRHVLRPASPQVLTVMGLSM 264
Cdd:PRK15081 168 DSW-------QHYI-LPSLTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQF 239

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499973115 265 TYLLGGSFIVESYFAVPGIGWTVLNAVSSHDLPVMQAILSLTVVIFVVIFILVDLGYALIDPRV 328
Cdd:PRK15081 240 GFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLYAAINPAI 303
oppB PRK09471
oligopeptide ABC transporter permease OppB;
19-328 1.63e-43

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 151.76  E-value: 1.63e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115  19 LKAVGVRLLAGIP-VFLLVTFSATaLSSLMPGSAaqlILGENATQAQIDA-LNSRYGYDLPVWERYLGWLGRLLQGDLGQ 96
Cdd:PRK09471   2 LKFILRRCLEAIPtLFILITISFF-MMRLAPGSP---FTGERTLPPEVMAnIEAKYHLNDPIMTQYFSYLKQLAHGDFGP 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115  97 TM-FSQQSVAKLLVDRAAVTFEIALLAMFVSLLIGLPLAMYTASRPGGIEDTVLRAVSSVMLSIPTFVIVVLLGFVFAIV 175
Cdd:PRK09471  78 SFkYKDYSVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGFAMTGVVIPSFVVAPLLVLIFAIT 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 176 LRWLPATGWVSfsddpiGNLYYVALPVMCLSVHQAAYFYRVSRSEFVAILQEDYVLVARAKGLPTRYILMRHVLRPASPQ 255
Cdd:PRK09471 158 LHWLPGGGWNG------GALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRRIILRHALKPALLP 231

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499973115 256 VLTVMGLSMTYLLGGSFIVESYFAVPGIGWTVLNAVSSHDLPVmqaILSLTVVI---FVVIFILVDLGYALIDPRV 328
Cdd:PRK09471 232 VLSYMGPAFVGIITGSMVIETIFGLPGIGQLFVNGALNRDYSL---VLSLTILVgalTILFNAIVDVLYAVIDPKI 304
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 25-328 7.53e-42

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 147.54  E-value: 7.53e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115  25 RLLAGIPVFLLVTFSATALSSLMPGSAAQLILGEN---ATQAQIDALNSRYGYDLPVWERYLGWLGRLLQGDLGQTMFSQ 101
Cdd:PRK10352   8 RLLLLIPMLLAASVIIFLMLRLGTGDPALDYLRLSnlpPTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDFGISFATQ 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 102 QSVAKLLVDRAAVTFEIALLAMFVSLLIGLPLAMYTASRPGGIEDTVLRAVSSVMLSIPTFVIVVLLGFVFAIVLRWLPA 181
Cdd:PRK10352  88 RPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSVYLQWLPA 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 182 TGWvsfsddpiGNLYYVALPVMCLSVHQAAYFYRVSRSEFVAILQEDYVLVARAKGLPTRYILMRHVLRPASPQVLTVMG 261
Cdd:PRK10352 168 MGY--------GGWQHIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERRHILRNASLPMITAVG 239

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499973115 262 LSMTYLLGGSFIVESYFAVPGIGWTVLNAVSSHDLPVMQAILSLTVVIFVVIFILVDLGYALIDPRV 328
Cdd:PRK10352 240 MHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRI 306
SapB COG4168
ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];
75-326 1.11e-36

ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];


Pssm-ID: 443329 [Multi-domain]  Cd Length: 321  Bit Score: 134.19  E-value: 1.11e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115  75 DLPVWERYLGWLGRLLQGDLGQTMFSQQSVAKLLVDRAAVTFEIALLAMFVSLLIGLPLAMYTASRPGGIEDTVLRAVSS 154
Cdd:COG4168   37 DASLFSGYLFYLQNLLQGDFGISSINGEPILEQLLTVFPATLELCFLAFLLALLIGIPLGILAGIYRGKWLDKLISSLSL 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 155 VMLSIPTFVIVVLLGFVFAIVLRWLPATGWVS-----------------FSDDP------IGNLYYVALPVMCLSVHQAA 211
Cdd:COG4168  117 LGFSIPVFWLALLLILFFSLNLGWLPVSGRYNllyeippvtgfalidawLSDSPyrlkaiQSALQHLILPTLVLAVAPTT 196

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 212 YFYRVSRSEFVAILQEDYVLVARAKGLPTRYILMRHVLRPASPQVLTVMGLSMTYLLGGSFIVESYFAVPGIGWTVLNAV 291
Cdd:COG4168  197 EVIRLTRQSTEEVMNQNYIKAAATRGLSRFTIIRRHVLRNALPPIIPQLGLQFSTMLTLAMITEVVFSWPGIGRWLINAI 276

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 499973115 292 SSHDLPVMQAILsLTVVIFVVIF-ILVDLGYALIDP 326
Cdd:COG4168  277 RQQDYAAISAGV-IVIGTFVIIVnILSDILGALLNP 311
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
25-328 2.08e-36

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 133.78  E-value: 2.08e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115  25 RLLAGIPVFLLVTFSATALSSLMPGSAAQLILGENATQAQIDA-LNSRYGYDLPVWERYLGWLGRLLQGDLGQTMFSQQS 103
Cdd:PRK10914   8 RLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGISPERHAqLLAELGLDKPMWQQYLHYIWGVMHGDLGISLKSRIP 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 104 VAKLLVDRAAVTFEIALLAMFVSLLIGLPLAMYTASRPGGIEDTVLRAVSSVMLSIPTFVIVVLLGFVFAIVLRWLPATG 183
Cdd:PRK10914  88 VWDEFVPRFKATLELGVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHWNLTPVSG 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 184 WVS---FSDDP--------------------IGNLYYVALPVMCLSVHQAAYFYRVSRSEFVAILQEDYVLVARAKGLPT 240
Cdd:PRK10914 168 RVSdmvFLDDSnpltgfmlidtaiwgedgnfIDAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTARAKGLTR 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 241 RYILMRHVLRPASPQVLTVMGLSMTYLLGGSFIVESYFAVPGIGWTVLNAVSSHDLPVMQAILSLTVVIFVVIFILVDLG 320
Cdd:PRK10914 248 MRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLL 327


                 ....*...
gi 499973115 321 YALIDPRV 328
Cdd:PRK10914 328 YGVVNPRI 335
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 65-329 1.75e-32

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 124.09  E-value: 1.75e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115  65 IDALNSRYGYDLPVWERYLGWLGRLLQGDLGQTMFSQQSVAKLLVDRAAVTFEIALLAMFVSLLIGLPLAMYTASRPGGI 144
Cdd:PRK15133  86 IAEITHRYGFDKPLHERYFKMLWDYIRFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAVRNGSR 165

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 145 EDTVLRAVSSVMLSIPTFVIVVLLGFVFA--IVLRWLPATGWVS--FSDDP-----IGNLYYVALPVMCLSVHQAAYFYR 215
Cdd:PRK15133 166 FDVWSSAFIIIGYAIPAFLFAILLIVFFAggSYFDLFPLRGLVSanFDSLPwyqkiTDYLWHITLPVLATVIGGFAALTM 245

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 216 VSRSEFVAILQEDYVLVARAKGLPTRYILMRHVLRPAspQVLTVMGLSMTYL---LGGSFIVESYFAVPGIGWTVLNAVS 292
Cdd:PRK15133 246 LTKNSFLDEIRKQYVVTARAKGVSEKNILWKHVFRNA--MLLVIAGFPATFIsmfFTGSLLIEVMFSLNGLGLLGYEATV 323

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 499973115 293 SHDLPVMQAILSLTVVIFVVIFILVDLGYALIDPRVD 329
Cdd:PRK15133 324 SRDYPVMFGTLYIFTLIGLLLNIVSDISYTLVDPRID 360
PRK15110 PRK15110
peptide ABC transporter permease SapB;
79-326 6.55e-23

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 97.07  E-value: 6.55e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115  79 WERYLGWLGRLLQGDLGQTMFSQQSVAKLLVDRAAVTFEIALLAMFVSLLIGLPLAMYTASRPGGIEDTVLRAVSSVMLS 158
Cdd:PRK15110  41 WDAWVFWFNGLLHWDFGVSSINGQPISEQLKEVFPATMELCILAFGFALLVGIPVGIIAGVTRHKWQDNLISALALLGFS 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 159 IPTFVIVVLLGFVFAIVLRWLPATG-------------------WvsFSDDP------IGNLYYVALPVMCLSVHQAAYF 213
Cdd:PRK15110 121 IPVFWLALLLTLFFSLTLGWLPVSGrfdllyevkpvtgfalidaW--LSDSPwrdemiMSAIRHMILPVITLAVAPTTEV 198

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 214 YRVSRSEFVAILQEDYVLVARAKGLPTRYILMRHVLRPASPQVLTVMGLSMTYLLGGSFIVESYFAVPGIGWTVLNAVSS 293
Cdd:PRK15110 199 IRLMRISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQ 278

                        250       260       270
                 ....*....|....*....|....*....|...
gi 499973115 294 HDLPVMQAILSLTVVIFVVIFILVDLGYALIDP 326
Cdd:PRK15110 279 QDYAAISAGVMVVGSLVIIVNVLSDILGAMANP 311
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 130-330 1.78e-20

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 86.97  E-value: 1.78e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115  130 GLPLAMYTASRPGGIEDTVLRAVSSVMLSIPTFVIVVLLgfvfaivlrwlpatgwvsFSDDPIGNLYYVALPVMCLSVHQ 209
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILL------------------VVIAILSILGHGILPAIILALLG 62

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115  210 AAYFYRVSRSEFVAILQEDYVLVARAKGLPTRYILMRHVLRPASPQVLTVMGLSMTYLLGGSFIVESYFAVPGIGWTVLN 289
Cdd:pfam00528  63 WAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIE 142

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 499973115  290 AVSSHDLPVMQAILSLTVVIFVVIFILVDLGYALIDPRVDV 330
Cdd:pfam00528 143 AILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVRK 183
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 93-264 3.33e-14

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 71.68  E-value: 3.33e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115  93 DLGQTMFSQqsvaklLVDRAAVTFEIALLAMFVSLLIGLPLAMYTASRpGGIEDTVLRAVSSVMLSIPTFVIVVLLGFVF 172
Cdd:COG1173   65 QLGRDVLSR------LLYGARISLLVGLLAVLIALVIGVLLGLLAGYF-GGWVDAVLMRLVDVLLAFPSLLLAIALVAVL 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 173 AivlrwlpatgwvsfsddpiGNLYYVALPVMCLSVhqaAYFYRVSRSEFVAILQEDYVLVARAKGLPTRYILMRHVLRPA 252
Cdd:COG1173  138 G-------------------PGLLNVILALGLTGW---PGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNV 195

                        170
                 ....*....|..
gi 499973115 253 SPQVLTVMGLSM 264
Cdd:COG1173  196 LPPLIVQATLGI 207
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 112-316 7.06e-13

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 66.15  E-value: 7.06e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 112 AAVTFEIALLAMFVSLLIGLPLAMYTASRPGGIeDTVLRAVSSVMLSIPTFVIVVLLGFVFAIVLRWLPATGWvsfsddp 191
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKL-DRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGL------- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 192 ignlyyvALPVMCLSVHQAAYFYRVSRSEFVAILQEDYVLVARAKGLPTRYILMRHVLRPASPQVLTVMGLSMTYLLGGS 271
Cdd:cd06261   73 -------GLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEF 145

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 499973115 272 FIVESYFAVPGIGWTVLNAVSSHDLPVMQAILSLTVVIFVVIFIL 316
Cdd:cd06261  146 ALVSFLGGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 125-315 9.20e-03

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 37.66  E-value: 9.20e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 125 VSLLIGLPLAMYTA----------SRPGGIEDTVLRAVSSVMLSIPTFVIVVLLGFVFAIVLRWLPAT----GWVSFsdd 190
Cdd:PRK15021 142 ISVLFGLMLTLCSSvmgvlagalqGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAItvlfGWMSL--- 218

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499973115 191 pIGnlyyvalpvmclsvhqaayfyrVSRSEFVAILQEDYVLVARAKGLPTRYILMRHVLRPASPQVLT----VMGLSMTY 266
Cdd:PRK15021 219 -VG----------------------VVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTflpfILCSSITT 275

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 499973115 267 LLGGSFIVESY-FAVPGIGWTVLNAVSSHDLPVM--QAILSLTVVIFVVIFI 315
Cdd:PRK15021 276 LTSLDFLGFGLpLGSPSLGELLLQGKNNLQAPWLgiTAFLSVAILLSLLIFI 327
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH