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Conserved domains on  [gi|499972520|ref|WP_011653238|]
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MULTISPECIES: ABC transporter permease [Rhizobium]

Protein Classification

ABC transporter permease( domain architecture ID 11439449)

ABC transporter permease is the transmembrane (TM) subunit in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter which generally binds a type 2 PBP; similar to the permease subunit of ABC-type dipeptide/oligopeptide/nickel transport systems

Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 36-392 4.01e-87

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 265.44  E-value: 4.01e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520  36 AIGPWRLVAGKLVRQKVAMVAGAIILFLYLVGLFAEFLAPALPMTSRPQYTYAPPqgfsffvekpdgssefnfhvkgykv 115
Cdd:COG1173    1 PRSRWRRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPP------------------------- 55

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 116 eidkvalrrtfvvdetkvvpigffvkgaaydlwglipmnrhligplnqnDPMYLLGADRLGRDVFSRLVYGTRVSMSIGL 195
Cdd:COG1173   56 -------------------------------------------------SAAHWLGTDQLGRDVLSRLLYGARISLLVGL 86

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 196 VGVAMSLILGVVLGSISGFYGGWVDTLIQRVIEVVSAMPTIPLWLGLAAAIPLTWspvnvyFVITIIVSLLGWTSLAREV 275
Cdd:COG1173   87 LAVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGL------LNVILALGLTGWPGYARLV 160

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 276 RGRFLALRSEDFVVAARLDGSSEARLIFRHILPSLTSHILAVVTLAVPTMIVAETSLSFLGIGLKPPVVSWGVLLQDAQN 355
Cdd:COG1173  161 RAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSEGRN 240

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 499972520 356 irTVATAPWLLIWPSLAVVVAVLSFNFFGDGLRDAAD 392
Cdd:COG1173  241 --YLLTAPWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 36-392 4.01e-87

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 265.44  E-value: 4.01e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520  36 AIGPWRLVAGKLVRQKVAMVAGAIILFLYLVGLFAEFLAPALPMTSRPQYTYAPPqgfsffvekpdgssefnfhvkgykv 115
Cdd:COG1173    1 PRSRWRRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPP------------------------- 55

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 116 eidkvalrrtfvvdetkvvpigffvkgaaydlwglipmnrhligplnqnDPMYLLGADRLGRDVFSRLVYGTRVSMSIGL 195
Cdd:COG1173   56 -------------------------------------------------SAAHWLGTDQLGRDVLSRLLYGARISLLVGL 86

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 196 VGVAMSLILGVVLGSISGFYGGWVDTLIQRVIEVVSAMPTIPLWLGLAAAIPLTWspvnvyFVITIIVSLLGWTSLAREV 275
Cdd:COG1173   87 LAVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGL------LNVILALGLTGWPGYARLV 160

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 276 RGRFLALRSEDFVVAARLDGSSEARLIFRHILPSLTSHILAVVTLAVPTMIVAETSLSFLGIGLKPPVVSWGVLLQDAQN 355
Cdd:COG1173  161 RAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSEGRN 240

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 499972520 356 irTVATAPWLLIWPSLAVVVAVLSFNFFGDGLRDAAD 392
Cdd:COG1173  241 --YLLTAPWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 167-393 3.86e-51

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 173.38  E-value: 3.86e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 167 MYLLGADRLGRDVFSRLVYGTRVSMSIGLVGVAMSLILGVVLGSISGFYGGWVDTLIQRVIEVVSAMPTIPLWLGLAAAi 246
Cdd:PRK15082  79 QHWFGVDSLGRDIFSRILVGARISLAAGFFSVAIGAAIGTVLGLLAGYYEGWWDRIIMRICDVLFAFPGILLAIAVVAI- 157

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 247 pLTWSPVNVyfviTIIVSLLGWTSLAREVRGRFLALRSEDFVVAARLDGSSEARLIFRHILPSLTSHILAVVTLAVPTMI 326
Cdd:PRK15082 158 -LGSGMANV----IIAVAIFSIPAFARLVRGNTLVLKQQTYIESARSIGASDWTILLRHILPGTVSSIVVYFTMRIGTSI 232

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499972520 327 VAETSLSFLGIGLKPPVVSWGVLLQDAQniRTVATAPWLLIWPSLAVVVAVLSFNFFGDGLRDAADP 393
Cdd:PRK15082 233 ITAASLSFLGLGAQPPTPEWGAMLNEAR--ADMVIAPHVALFPSLAIFLTVLAFNLLGDGLRDALDP 297
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 188-362 5.88e-18

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 81.17  E-value: 5.88e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 188 RVSMSIGLVGVAMSLILGVVLGSISGFYGGWVDTLIQRVIEVVSAMPTI--PLWLGLAAAIPLTWSPVNVYFVITIIVSL 265
Cdd:cd06261    2 LNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLvlGLLLVLLFGVLLGWGILPGLGLPALILAL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 266 LGWTSLAREVRGRFLALRSEDFVVAARLDGSSEARLIFRHILPSLTSHILAVVTLAVPTMIVAETSLSFLGIGLkPPVVS 345
Cdd:cd06261   82 LLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGE-APGPG 160

                        170
                 ....*....|....*..
gi 499972520 346 WGVLLQDAQNIRTVATA 362
Cdd:cd06261  161 TGLLLIFAILFPGDLGV 177
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 205-393 3.26e-17

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 78.88  E-value: 3.26e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520  205 GVVLGSISGFY-GGWVDTLIQRVIEVVSAMPTIPLWLGLAAAIPLTWspVNVYFVITIIVSLLGWTSLAREVRGRFLALR 283
Cdd:pfam00528   1 GIPLGIIAALRrGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSI--LGHGILPAIILALLGWAGYARLIRRAALRSL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520  284 SEDFVVAARLDGSSEARLIFRHILPSLTSHILAVVTLAVPTMIVAETSLSFLGIGlkPPVvswGVLLQDAQNIRTVAtap 363
Cdd:pfam00528  79 PSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSW--PGL---GLLLIEAILGYDYP--- 150

                         170       180       190
                  ....*....|....*....|....*....|
gi 499972520  364 wLLIWPSLAVVVAVLSFNFFGDGLRDAADP 393
Cdd:pfam00528 151 -EIQGPVLAAALILLLLNLLVDILQRLLDP 179
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 36-392 4.01e-87

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 265.44  E-value: 4.01e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520  36 AIGPWRLVAGKLVRQKVAMVAGAIILFLYLVGLFAEFLAPALPMTSRPQYTYAPPqgfsffvekpdgssefnfhvkgykv 115
Cdd:COG1173    1 PRSRWRRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPP------------------------- 55

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 116 eidkvalrrtfvvdetkvvpigffvkgaaydlwglipmnrhligplnqnDPMYLLGADRLGRDVFSRLVYGTRVSMSIGL 195
Cdd:COG1173   56 -------------------------------------------------SAAHWLGTDQLGRDVLSRLLYGARISLLVGL 86

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 196 VGVAMSLILGVVLGSISGFYGGWVDTLIQRVIEVVSAMPTIPLWLGLAAAIPLTWspvnvyFVITIIVSLLGWTSLAREV 275
Cdd:COG1173   87 LAVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGL------LNVILALGLTGWPGYARLV 160

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 276 RGRFLALRSEDFVVAARLDGSSEARLIFRHILPSLTSHILAVVTLAVPTMIVAETSLSFLGIGLKPPVVSWGVLLQDAQN 355
Cdd:COG1173  161 RAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSEGRN 240

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 499972520 356 irTVATAPWLLIWPSLAVVVAVLSFNFFGDGLRDAAD 392
Cdd:COG1173  241 --YLLTAPWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 167-393 3.86e-51

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 173.38  E-value: 3.86e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 167 MYLLGADRLGRDVFSRLVYGTRVSMSIGLVGVAMSLILGVVLGSISGFYGGWVDTLIQRVIEVVSAMPTIPLWLGLAAAi 246
Cdd:PRK15082  79 QHWFGVDSLGRDIFSRILVGARISLAAGFFSVAIGAAIGTVLGLLAGYYEGWWDRIIMRICDVLFAFPGILLAIAVVAI- 157

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 247 pLTWSPVNVyfviTIIVSLLGWTSLAREVRGRFLALRSEDFVVAARLDGSSEARLIFRHILPSLTSHILAVVTLAVPTMI 326
Cdd:PRK15082 158 -LGSGMANV----IIAVAIFSIPAFARLVRGNTLVLKQQTYIESARSIGASDWTILLRHILPGTVSSIVVYFTMRIGTSI 232

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499972520 327 VAETSLSFLGIGLKPPVVSWGVLLQDAQniRTVATAPWLLIWPSLAVVVAVLSFNFFGDGLRDAADP 393
Cdd:PRK15082 233 ITAASLSFLGLGAQPPTPEWGAMLNEAR--ADMVIAPHVALFPSLAIFLTVLAFNLLGDGLRDALDP 297
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 169-393 5.10e-51

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 174.18  E-value: 5.10e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 169 LLGADRLGRDVFSRLVYGTRVSMSIGLVGVAMSLILGVVLGSISGFYGGWVDTLIQRVIEVVSAMPTIPLWLGLAAAIPL 248
Cdd:COG4239  122 WLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVAAGAVQGYFGGRVDLLFQRFIEIWSSMPELYLLIILSSIFQP 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 249 TwspvnvYFVITIIVSLLGWTSLAREVRGRFLALRSEDFVVAARLDGSSEARLIFRHILP-SLTshilAVVTLAVPTM-- 325
Cdd:COG4239  202 S------FWLLLGILLLFGWMGLVGVVRAEFLRARNLEYVRAARALGVSDRRIMFRHILPnAMV----ATLTFLPFILsg 271

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 326 -IVAETSLSFLGIGLKPPVVSWGVLL-QDAQNIrtvaTAPWLLIWPSLAVVVAVLSFNFFGDGLRDAADP 393
Cdd:COG4239  272 aITTLTSLDFLGFGLPPGSPSLGELLaQGKNNL----QAPWLGLSAFVVLALMLSLLVFIGEAVRDAFDP 337
nikC PRK10417
nickel transporter permease NikC; Provisional
 165-393 6.01e-51

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 172.16  E-value: 6.01e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 165 DPMYLLGADRLGRDVFSRLVYGTRVSMSIGLVGVAMSLILGVVLGSISGFYGGWVDTLIQRVIEVVSAMPTIPLWLGLAA 244
Cdd:PRK10417  44 DAQHWLGTDHLGRDIFSRLMAGTRVSLGSVMACLLLVLALGLVIGGSAGLLGGRVDQATMRVADMFMTFPTSILAFFMVG 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 245 AipLTWSPVNVyfVITIIVSLLGWtsLAREVRGRFLALRSEDFVVAARLDGSSEARLIFRHILPSLTSHILAVVTLAVPT 324
Cdd:PRK10417 124 V--LGTGLTNV--IIAIALSHWAW--YARMVRSLVISLRQREFVLAARLSGAGHVRVFIDHLLPAVIPQLLVLATLDIGH 197

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499972520 325 MIVAETSLSFLGIGLKPPVVSWGVLLQDAQNIrtVATAPWLLIWPSLAVVVAVLSFNFFGDGLRDAADP 393
Cdd:PRK10417 198 MMLHVAGLSFLGLGVTAPTAEWGVMINDARQY--IWTQPLLMFWPGLALFISVMAFNLLGDALRDHLDP 264
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 170-395 6.05e-44

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 154.61  E-value: 6.05e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 170 LGADRLGRDVFSRLVYGTRVSMSIGLVGVAMSLILGVVLGSISGFYGGWVDTLIQRVIEVVSAMPTIPLWLGLaaaipLT 249
Cdd:PRK15406  84 FGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILL-----VT 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 250 WSPVNVyFVITIIVSLLGWTSLAREVRGRFLALRSEDFVVAARLDGSSEARLIFRHILPSLTSHILAVVTLAVPTMIVAE 329
Cdd:PRK15406 159 FFGQNI-LLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRGIVLRHIVPNVLGVVVVYASLLVPSMILFE 237

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499972520 330 TSLSFLGIGLKPPVVSWGVLLQDAQNirTVATAPWLLIWPSLAVVVAVLSFNFFGDGLRDAADPYD 395
Cdd:PRK15406 238 SFLSFLGLGTQEPLSSWGALLSDGAN--SMEVSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDPKD 301
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
168-393 2.34e-43

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 153.01  E-value: 2.34e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 168 YLLGADRLGRDVFSRLVYGTRVSMSIGLVGVAMSLILGVVLGSISGFYGGWVDTLIQRVIEVVSAMPTIPLWLGLAAAip 247
Cdd:PRK10913  79 HILGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLVMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAI-- 156

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 248 LTWSPVNVYFVITiIVSLLGWTSLAREVrgrFLALRSEDFVVAARLDGSSEARLIFRHILPSLTSHILAVVTLAVPTMIV 327
Cdd:PRK10913 157 FGPSIVNAALALT-FVALPHYVRLTRAA---VLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAIL 232

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499972520 328 AETSLSFLGIGLKPPVVSWGVLLQDAqnIRTVATAPWLLIWPSLAVVVAVLSFNFFGDGLRDAADP 393
Cdd:PRK10913 233 DMAALGFLGMGAQPPTPEWGTMLSDV--LQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDP 296
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 170-393 1.77e-39

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 143.97  E-value: 1.77e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 170 LGADRLGRDVFSRLVYGTRVSMSIGLVGVAMSLILGVVLGSISGFYGGWVDTLIQRVIEVVSAMPTIPLWLGLAAAIplt 249
Cdd:PRK15021 123 LGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVLAGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVV--- 199

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 250 wSPvNVYFVITIIVsLLGWTSLAREVRGRFLALRSEDFVVAARLDGSSEARLIFRHILPSLTSHILAVVTLAVPTMIVAE 329
Cdd:PRK15021 200 -QP-NFWWLLAITV-LFGWMSLVGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTL 276

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499972520 330 TSLSFLGIGLKPPVVSWG-VLLQDAQNIRtvatAPWLLIWPSLAVVVAVLSFNFFGDGLRDAADP 393
Cdd:PRK15021 277 TSLDFLGFGLPLGSPSLGeLLLQGKNNLQ----APWLGITAFLSVAILLSLLIFIGEAVRDAFDP 337
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
171-393 1.16e-37

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 137.64  E-value: 1.16e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 171 GADRLGRDVFSRLVYGTRVSMSIGLVGVAMSLILGVVLGSISGFYGGWVDTLIQRVIEVVSAMPTIPLWLGLAAAipLTW 250
Cdd:PRK09881  77 GTDEVGRDLFSRVLVGSQQSILAGLVVVAIAGMIGSLLGCLSGVLGGRADAIIMRIMDIMLSIPSLVLTMALAAA--LGP 154

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 251 SPVNVYFVITiIVSLLGWTSLArevRGRFLALRSEDFVVAARLDGSSEARLIFRHILPSLTSHILAVVTLAVPTMIVAET 330
Cdd:PRK09881 155 SLFNAMLAIA-IVRIPFYVRLA---RGQALVVRQYTYVQAAKTFGASRWHLISWHILRNSLPPLIVQASLDIGSAILMAA 230

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499972520 331 SLSFLGIGLKPPVVSWGVLLQDAQNIrtVATAPWLLIWPSLAVVVAVLSFNFFGDGLRDAADP 393
Cdd:PRK09881 231 TLGFIGLGAQQPSAEWGAMVANGRNY--VLDQWWYCAFPGAAILLTAVGFNLFGDGIRDLLDP 291
PRK15111 PRK15111
peptide ABC transporter permease SapC;
168-390 3.05e-22

peptide ABC transporter permease SapC;


Pssm-ID: 185066 [Multi-domain]  Cd Length: 296  Bit Score: 95.54  E-value: 3.05e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 168 YLLGADRLGRDVFSRLVYGTRVSMSIGLVGVAMSLILGVVLGSISGFYGGWVDTLIQRVIEVVSAMPTIPLWLGLAAAIp 247
Cdd:PRK15111  76 FFLGTDDLGRDVLSRLLSGAAPTVGGAFVVTLAATLCGLVLGVFAGATHGLRSAVLNHILDTLLSIPSLLLAIIVVAFA- 154

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 248 ltwSPVNVYFVITIIVSLLgwtslAREVRGRFLALRSE---DFVVAARLDGSSEARLIFRHILPSLTSHILAVVTLAVPT 324
Cdd:PRK15111 155 ---GPSLSHAMFAVWLALL-----PRMVRSIYSAVHDElekEYVIAARLDGASTLNILWYAVLPNITAGLVTEITRALSM 226

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499972520 325 MIVAETSLSFLGIGLKPPVVSWGVLLQDAqnIRTVATAPWLLIWPSLAVVVAVLSFNFFGDGLRDA 390
Cdd:PRK15111 227 AILDIAALGFLDLGAQLPSPEWGAMLGDS--LELIYVAPWTVMLPGAAIMLSVLLVNLLGDGIRRA 290
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 188-362 5.88e-18

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 81.17  E-value: 5.88e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 188 RVSMSIGLVGVAMSLILGVVLGSISGFYGGWVDTLIQRVIEVVSAMPTI--PLWLGLAAAIPLTWSPVNVYFVITIIVSL 265
Cdd:cd06261    2 LNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLvlGLLLVLLFGVLLGWGILPGLGLPALILAL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 266 LGWTSLAREVRGRFLALRSEDFVVAARLDGSSEARLIFRHILPSLTSHILAVVTLAVPTMIVAETSLSFLGIGLkPPVVS 345
Cdd:cd06261   82 LLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGE-APGPG 160

                        170
                 ....*....|....*..
gi 499972520 346 WGVLLQDAQNIRTVATA 362
Cdd:cd06261  161 TGLLLIFAILFPGDLGV 177
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 205-393 3.26e-17

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 78.88  E-value: 3.26e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520  205 GVVLGSISGFY-GGWVDTLIQRVIEVVSAMPTIPLWLGLAAAIPLTWspVNVYFVITIIVSLLGWTSLAREVRGRFLALR 283
Cdd:pfam00528   1 GIPLGIIAALRrGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSI--LGHGILPAIILALLGWAGYARLIRRAALRSL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520  284 SEDFVVAARLDGSSEARLIFRHILPSLTSHILAVVTLAVPTMIVAETSLSFLGIGlkPPVvswGVLLQDAQNIRTVAtap 363
Cdd:pfam00528  79 PSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSW--PGL---GLLLIEAILGYDYP--- 150

                         170       180       190
                  ....*....|....*....|....*....|
gi 499972520  364 wLLIWPSLAVVVAVLSFNFFGDGLRDAADP 393
Cdd:pfam00528 151 -EIQGPVLAAALILLLLNLLVDILQRLLDP 179
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 174-338 9.03e-11

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 62.39  E-value: 9.03e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 174 RLGRDVFSRLVYGTRVSMSIGLVGVAMSLILGVVLGSISGFY-GGWVDTLIQRVIEVVSAMPTipLWLGLAA----AIPL 248
Cdd:COG0601   82 VYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRrGSWLDRLITVLALLGISIPS--FWLGLLLillfAVKL 159

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499972520 249 TWSPVNVYFVI--------------TIIVSLLGWTSLAREVRGRFLALRSEDFVVAARLDGSSEARLIFRHILP-SLTSh 313
Cdd:COG0601  160 GWLPVSGRVSPwedfldalrhlilpALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRnALIP- 238

                        170       180
                 ....*....|....*....|....*....
gi 499972520 314 ILAVVTLAVPTMI----VAETSLSFLGIG 338
Cdd:COG0601  239 VVTVLGLQLGGLLggavVVETVFSWPGLG 267
OppC_N pfam12911
N-terminal TM domain of oligopeptide transport permease C; Oligopeptide permeases (Opp) have ...
 38-90 1.07e-07

N-terminal TM domain of oligopeptide transport permease C; Oligopeptide permeases (Opp) have been identified in numerous gram-negative and -positive bacteria. These transport systems belong to the superfamily of highly conserved ATP-binding cassette transporters. Typically, Opp importers comprise a complex of five proteins. The oligopeptide-binding protein OppA is responsible for the capture of peptides from the external medium. Two integral highly hydrophobic membrane spanning proteins, OppB and OppC, form a channel through the membrane used for peptide translocation. This N-terminal domain appears to be the first TM domain of the molecule.


Pssm-ID: 463747 [Multi-domain]  Cd Length: 53  Bit Score: 48.18  E-value: 1.07e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 499972520   38 GPWRLVAGKLVRQKVAMVAGAIILFLYLVGLFAEFLAPALPMTSRPQYTYAPP 90
Cdd:pfam12911   1 SPWQDAWRRFRRNKLAMVGLVILLLLVLLAIFAPLLAPYDPDQQDLSADLLPP 53
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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