|
Name |
Accession |
Description |
Interval |
E-value |
| PBP2_ChoS |
cd13610 |
Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; ... |
235-498 |
3.39e-152 |
|
Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270328 Cd Length: 264 Bit Score: 434.71 E-value: 3.39e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 235 TITLAGKLGSEPSIITNMYKILIEDETDD-TVDVKDGMGKTSFLFNALKSDDIDGYLEFTGTVLGELTKEDLKSKKEDAV 313
Cdd:cd13610 1 SIVIAGKLGSEPDILINMYKLLIEEETPDlQVTLKPNFGKTSFLFNALKSGDIDIYPEFTGTVLETLLKEPPKSNDPMEV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 314 YQQAKQSLEKKYDMTMLKPMKYNNTYALAVKRDFAKENNIKTIGDLQKVEDKIKPGFTMEFNDRSDGYKAVAKAYGLNLs 393
Cdd:cd13610 81 YEQARDGLAKQYQLTYLKPMAYNNTYALAVKKEFAKQHNLKTISDLQKVQDKLKAGFTLEFMDREDGYKGLQKAYGLNF- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 394 NVKKMEPKLRYTAVEKGDINLIDAYSTDAELKQYNMVVLKDDKHVFPPYQGAPMFKEKFLKQHPEIKKPLNKLEGKISDE 473
Cdd:cd13610 160 NVKSMEPALRYQAINNGQVNVIDAYSTDSEIKQYDLVVLKDDKHLFPPYQGAPLMREEFLKKHPELVKALNKLAGKITDE 239
|
250 260
....*....|....*....|....*
gi 499595699 474 EMQEMNYKVTVKNEDPYNVAKHYLE 498
Cdd:cd13610 240 EMQEMNYRVDVKHKSAAKVAKEYLQ 264
|
|
| OsmF |
COG1732 |
Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system ... |
207-500 |
2.18e-116 |
|
Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441338 [Multi-domain] Cd Length: 294 Bit Score: 344.44 E-value: 2.18e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 207 KKLLITVGAMILIILLVIVVPLFGKKGDTITLAGKLGSEPSIITNMYKILIEDEtDDTVDVKDGMGKTSFLFNALKSDDI 286
Cdd:COG1732 3 RLLLLALALAAALALAGCGLASAAAAGDTIVVGSKNFTEQEILAEIYAQALEAA-GLKVERKLNLGGTEVVRQALKSGEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 287 DGYLEFTGTVLGELTKEDlKSKKEDAVYQQAKQSLEKKYDMTMLKPMKYNNTYALAVKRDFAKENNIKTIGDLQKVEDKI 366
Cdd:COG1732 82 DLYPEYTGTALTTYLKED-PITDPEEVYEAVKEALPEKNGLTWLDPAGFNNTYALAVTKETAEKYGLKTISDLAKVAGEL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 367 KPGFTMEFNDRSDGYKAVAKAYGLNLSNVKKMEPKLRYTAVEKGDINLIDAYSTDAELKQYNMVVLKDDKHVFPPYQGAP 446
Cdd:COG1732 161 TLGADPEFAERPDGLPGLKKAYGFEFKEVKPMDTGLTYTALANGQVDVADAYTTDGRIAALDLVVLEDDKNFFPPYNAAP 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 499595699 447 MFKEKFLKQHPEIKKPLNKLEGKISDEEMQEMNYKVTVKNEDPYNVAKHYLEKE 500
Cdd:COG1732 241 LVRKEVLEKYPELAEVLNKLSGKLTTETMQELNYQVDVDGEDPADVAREFLKEK 294
|
|
| OpuBB |
COG1174 |
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ... |
2-204 |
8.90e-91 |
|
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];
Pssm-ID: 440787 [Multi-domain] Cd Length: 212 Bit Score: 275.78 E-value: 8.90e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 2 SELFSTLNDRKGEVLTTILEHIQISFIALLIAILIAVPLGIALTKTKRLSEVVMNIAAILQTIPSLALLGLMIPIFGIGR 81
Cdd:COG1174 3 LSLIEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGIGP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 82 VPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGIGMKPMRRLTKVELPIAMPVMMAGIRTAMVLIIGTATLAALIGA 161
Cdd:COG1174 83 APAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALIGA 162
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 499595699 162 GGLGDLILLGIDRNNTSLILIGAIPAALLAIMFDLILRYMEKL 204
Cdd:COG1174 163 GGLGDLIFDGLQLNNTALILAGAILVALLALLVDLLLALLERL 205
|
|
| OpuAC |
pfam04069 |
Substrate binding domain of ABC-type glycine betaine transport system; Part of a high affinity ... |
234-499 |
1.76e-59 |
|
Substrate binding domain of ABC-type glycine betaine transport system; Part of a high affinity multicomponent binding-protein-dependent transport system involved in bacterial osmoregulation. This domain is often fused to the permease component of the transporter complex. Family members are often integral membrane proteins or predicted to be attached to the membrane by a lipid anchor. Glycine betaine is involved in protection from high osmolarity environments for example in Bacillus subtilis. The family member OpuBC is closely related, and involved in choline transport. Choline is necessary for the biosynthesis of glycine betaine. L-carnitine is important for osmoregulation in Listeria monocytogenes. Family also contains proteins binding l-proline (ProX), histidine (HisX) and taurine (TauA).
Pssm-ID: 397954 [Multi-domain] Cd Length: 257 Bit Score: 196.78 E-value: 1.76e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 234 DTITLAGKLGSEPSIITNMYKILIEDetDDTVDVKDGMGKTSFLFNALKSDDIDGYL-EFTGTVlgeltkedlkskkeda 312
Cdd:pfam04069 1 KTIVIGSKNWTEQEILANIAAQLLEA--LGYVVELVGLGSSAVLFAALASGDIDLYPeEWTGTT---------------- 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 313 vYQQAKQSLEKKYDMTMLKPMKYNNTYALAVKRDFAKENNIKTIGDLQKVEDKIKPGFTMEFNDRSDGY------KAVAK 386
Cdd:pfam04069 63 -YEAYKKAVEEKLGLLVLGPLGAGNTYGLAVPKYVAEKPGIKSISDLAKPADDLELGFKGEFIGRPDGWgcmrstEGLLK 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 387 AYGLNL-----SNVKKMEPkLRYTAVEKGDINLIDAYSTDAELKQYNMVVLKDDKHVFPP-YQGAPMFKEKFLKQHPEIK 460
Cdd:pfam04069 142 AYGLDKyelveGSEAAMDA-LIYAAYKRGEPDVVYAWTPDWMIKKYDLVVLEDPKGLFPPaYNVVPVVRKGFAEKHPEVA 220
|
250 260 270
....*....|....*....|....*....|....*....
gi 499595699 461 KPLNKLegKISDEEMQEMNYKVTVKNEDPYNVAKHYLEK 499
Cdd:pfam04069 221 AFLNKL--SLDTEDLNELNAQVDVEGKDPEEVAKDWLAE 257
|
|
| PRK10952 |
PRK10952 |
proline/glycine betaine ABC transporter permease ProW; |
39-195 |
2.15e-24 |
|
proline/glycine betaine ABC transporter permease ProW;
Pssm-ID: 236805 Cd Length: 355 Bit Score: 104.40 E-value: 2.15e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 39 PLGIALTKTKRLSEVVMNIAAILQTIPSLALLGLMIPIFGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGI 118
Cdd:PRK10952 166 PLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPPIVRLTILGINQVPADLIEASRSF 245
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499595699 119 GMKPMRRLTKVELPIAMPVMMAGIRTAMVLIIGTATLAALIGAGGLGDLILLGIDRNNTSLILIGAIPAALLAIMFD 195
Cdd:PRK10952 246 GASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQMVLRGIGRLDMGLATVGGVGIVILAIILD 322
|
|
| BPD_transp_1 |
pfam00528 |
Binding-protein-dependent transport system inner membrane component; The alignments cover the ... |
38-203 |
8.21e-24 |
|
Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.
Pssm-ID: 334128 [Multi-domain] Cd Length: 183 Bit Score: 98.14 E-value: 8.21e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 38 VPLGI--ALTKTKRLSEVVMNIAAILQTIPSLALLGLMIP-----IFGIGRVPAIIALVVYALLPILRNTYTGIKEVDPS 110
Cdd:pfam00528 2 IPLGIiaALRRGRRLDRLLRPLIDLLQALPSFVLAILLVViailsILGHGILPAIILALLGWAGYARLIRRAALRSLPSD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 111 LIEAAKGIGMKPMRRLTKVELPIAMPVMMAGIRTAMVLIIGTATLAALIGA-----GGLGDLILLGIDRNNTSLILIGAI 185
Cdd:pfam00528 82 LVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSwpglgLLLIEAILGYDYPEIQGPVLAAAL 161
|
170
....*....|....*...
gi 499595699 186 PAALLAIMFDLILRYMEK 203
Cdd:pfam00528 162 ILLLLNLLVDILQRLLDP 179
|
|
| TM_PBP2 |
cd06261 |
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ... |
38-194 |
5.15e-20 |
|
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.
Pssm-ID: 119394 [Multi-domain] Cd Length: 190 Bit Score: 87.72 E-value: 5.15e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 38 VPLGIALT-KTKRLSEVVMNIAAILQTIPSLALLGLMIPIFGIGRV---------PAIIALVVYALLPILRNTYTGIKEV 107
Cdd:cd06261 20 LLLGIILArKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGwgilpglglPALILALLLIAPFARLIRRAALESI 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 108 DPSLIEAAKGIGMKPMRRLTKVELPIAMPVMMAGIRTAMVLIIGTATLAALIGAGGLGDLILLGIDRNNTSLILIGAIPA 187
Cdd:cd06261 100 PKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPGTGLLLIFAILFPGDLGVAA 179
|
....*..
gi 499595699 188 ALLAIMF 194
Cdd:cd06261 180 AVALILL 186
|
|
| PhnE |
TIGR01097 |
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ... |
1-151 |
7.00e-07 |
|
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]
Pssm-ID: 273441 [Multi-domain] Cd Length: 250 Bit Score: 50.62 E-value: 7.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 1 MSELFSTLNDRKGEVLTTILEHIQISFIALLIAILIAVPLGI----ALTKTKRLSEVVMNIAAILQTIPSLALLGLMIPI 76
Cdd:TIGR01097 42 LGRMFPPDWSYLPRILKALLETLAMAILGTVLAAVLAVPLALlaarNITPSPWLYGLARLLLNFLRAIPELVWALIFVAA 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 77 FGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGIGMKPMRRLTKVELPIAMPVMMA--------GIRTAMVL 148
Cdd:TIGR01097 122 VGLGPFAGVLALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQVLPQFLSytlyrfeiNVRAAAVL 201
|
....
gi 499595699 149 -IIG 151
Cdd:TIGR01097 202 gLVG 205
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PBP2_ChoS |
cd13610 |
Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; ... |
235-498 |
3.39e-152 |
|
Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270328 Cd Length: 264 Bit Score: 434.71 E-value: 3.39e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 235 TITLAGKLGSEPSIITNMYKILIEDETDD-TVDVKDGMGKTSFLFNALKSDDIDGYLEFTGTVLGELTKEDLKSKKEDAV 313
Cdd:cd13610 1 SIVIAGKLGSEPDILINMYKLLIEEETPDlQVTLKPNFGKTSFLFNALKSGDIDIYPEFTGTVLETLLKEPPKSNDPMEV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 314 YQQAKQSLEKKYDMTMLKPMKYNNTYALAVKRDFAKENNIKTIGDLQKVEDKIKPGFTMEFNDRSDGYKAVAKAYGLNLs 393
Cdd:cd13610 81 YEQARDGLAKQYQLTYLKPMAYNNTYALAVKKEFAKQHNLKTISDLQKVQDKLKAGFTLEFMDREDGYKGLQKAYGLNF- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 394 NVKKMEPKLRYTAVEKGDINLIDAYSTDAELKQYNMVVLKDDKHVFPPYQGAPMFKEKFLKQHPEIKKPLNKLEGKISDE 473
Cdd:cd13610 160 NVKSMEPALRYQAINNGQVNVIDAYSTDSEIKQYDLVVLKDDKHLFPPYQGAPLMREEFLKKHPELVKALNKLAGKITDE 239
|
250 260
....*....|....*....|....*
gi 499595699 474 EMQEMNYKVTVKNEDPYNVAKHYLE 498
Cdd:cd13610 240 EMQEMNYRVDVKHKSAAKVAKEYLQ 264
|
|
| OsmF |
COG1732 |
Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system ... |
207-500 |
2.18e-116 |
|
Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441338 [Multi-domain] Cd Length: 294 Bit Score: 344.44 E-value: 2.18e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 207 KKLLITVGAMILIILLVIVVPLFGKKGDTITLAGKLGSEPSIITNMYKILIEDEtDDTVDVKDGMGKTSFLFNALKSDDI 286
Cdd:COG1732 3 RLLLLALALAAALALAGCGLASAAAAGDTIVVGSKNFTEQEILAEIYAQALEAA-GLKVERKLNLGGTEVVRQALKSGEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 287 DGYLEFTGTVLGELTKEDlKSKKEDAVYQQAKQSLEKKYDMTMLKPMKYNNTYALAVKRDFAKENNIKTIGDLQKVEDKI 366
Cdd:COG1732 82 DLYPEYTGTALTTYLKED-PITDPEEVYEAVKEALPEKNGLTWLDPAGFNNTYALAVTKETAEKYGLKTISDLAKVAGEL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 367 KPGFTMEFNDRSDGYKAVAKAYGLNLSNVKKMEPKLRYTAVEKGDINLIDAYSTDAELKQYNMVVLKDDKHVFPPYQGAP 446
Cdd:COG1732 161 TLGADPEFAERPDGLPGLKKAYGFEFKEVKPMDTGLTYTALANGQVDVADAYTTDGRIAALDLVVLEDDKNFFPPYNAAP 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 499595699 447 MFKEKFLKQHPEIKKPLNKLEGKISDEEMQEMNYKVTVKNEDPYNVAKHYLEKE 500
Cdd:COG1732 241 LVRKEVLEKYPELAEVLNKLSGKLTTETMQELNYQVDVDGEDPADVAREFLKEK 294
|
|
| PBP2_osmoprotectants |
cd13528 |
Substrate-binding domain of osmoregulatory ABC-type transporters; the type 2 ... |
235-498 |
2.32e-111 |
|
Substrate-binding domain of osmoregulatory ABC-type transporters; the type 2 periplasmic-binding protein fold; This family represents the periplasmic substrate-binding component of ABC transport systems that are involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. To counteract the efflux of water, bacteria and archaea accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270246 [Multi-domain] Cd Length: 264 Bit Score: 330.71 E-value: 2.32e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 235 TITLAGKLGSEPSIITNMYKILIEDETDDTVDVKDGMGKTSFLFNALKSDDIDGYLEFTGTVLGELTKEDLKSKKEDAVY 314
Cdd:cd13528 1 TIVVGSKNFTEQYILGEMLAQLLEANTDLTVERKLNLGGTEVAFNALKNGDIDLYVEYTGTALLTILKEDAPITDPEEVY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 315 QQAKQSLEKKYDMTMLKPMKYNNTYALAVKRDFAKENNIKTIGDLQKVEDKIKPGFTMEFNDRSDGYKAVAKAYGLNLSN 394
Cdd:cd13528 81 EKVKKEYEEKFGLTWLDPLGFNNTYALAVRKDTAEKYGLKTISDLAPHSDQLVFGADPEFYERSDGLPGLKKTYGFDFKE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 395 VKKMEPKLRYTAVEKGDINLIDAYSTDAELKQYNMVVLKDDKHVFPPYQGAPMFKEKFLKQHPEIKKPLNKLEGKISDEE 474
Cdd:cd13528 161 VKTMDPGLTYEALDNGEVDVIDAFSTDGRIKAFDLVVLEDDKNFFPPYNAAPVVREDVLKKHPELEEVLNKLSGKLTDET 240
|
250 260
....*....|....*....|....
gi 499595699 475 MQEMNYKVTVKNEDPYNVAKHYLE 498
Cdd:cd13528 241 MQQLNYQVDVEGKDPEEVARDFLK 264
|
|
| PBP2_Opu_like_1 |
cd13609 |
Substrate-binding domain of putative ABC-type osmoprotectant uptake system; the type 2 ... |
235-498 |
2.40e-98 |
|
Substrate-binding domain of putative ABC-type osmoprotectant uptake system; the type 2 periplasmic-binding protein fold; This group includes the periplasmic substrate-binding component of a putative ABC transport system that is predicted to be involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. The relative substrate preference of this group is not known. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270327 Cd Length: 263 Bit Score: 297.21 E-value: 2.40e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 235 TITLAGKLGSEPSIITNMYKILIEDETDDTVDVKDGMGKTSFLFNALKSDDIDGYLEFTGTVLGELTKEDLKSKkEDAVY 314
Cdd:cd13609 1 TIVIGSKNFTEQLILGNMYADLIEANTDIKVERKLNLGGSSVCFSALKNGDIDMYVDYTGTILVNILKEPPISD-PDEVY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 315 QQAKQSLEKKYDMTMLKPMKYNNTYALAVKRDFAKENNIKTIGDLQKVEDKIKPGFTMEFNDRSDGYKAVAKAYGLNLSN 394
Cdd:cd13609 80 NTVKELMKEKYNLEVLKPLGFNNTYTLAVRKETAEKYNLKTISDLAKVSDELTLGCTLEFLNREDGLPGLEKTYGLNFKD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 395 VKKMEPKLRYTAVEKGDINLIDAYSTDAELKQYNMVVLKDDKHVFPPYQGAPMFKEKFLKQHPEIKKPLNKLEGKISDEE 474
Cdd:cd13609 160 VKGLDGSLRYTALENGEVDVIDAFSTDGLLKKFDLVVLEDDKNFFPPYYAVPLVREETLEKYPELEDVLNKLAGKISEET 239
|
250 260
....*....|....*....|....
gi 499595699 475 MQEMNYKVTVKNEDPYNVAKHYLE 498
Cdd:cd13609 240 MRELNYKVDELGKDPEDVAHEFLV 263
|
|
| OpuBB |
COG1174 |
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ... |
2-204 |
8.90e-91 |
|
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];
Pssm-ID: 440787 [Multi-domain] Cd Length: 212 Bit Score: 275.78 E-value: 8.90e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 2 SELFSTLNDRKGEVLTTILEHIQISFIALLIAILIAVPLGIALTKTKRLSEVVMNIAAILQTIPSLALLGLMIPIFGIGR 81
Cdd:COG1174 3 LSLIEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGIGP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 82 VPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGIGMKPMRRLTKVELPIAMPVMMAGIRTAMVLIIGTATLAALIGA 161
Cdd:COG1174 83 APAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALIGA 162
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 499595699 162 GGLGDLILLGIDRNNTSLILIGAIPAALLAIMFDLILRYMEKL 204
Cdd:COG1174 163 GGLGDLIFDGLQLNNTALILAGAILVALLALLVDLLLALLERL 205
|
|
| PBP2_ProWX |
cd13612 |
Substrate-binding protein ProWX of ABC-type osmoregulated transporter and its related proteins; ... |
235-502 |
1.46e-80 |
|
Substrate-binding protein ProWX of ABC-type osmoregulated transporter and its related proteins; the type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein ProWX of Helicobacter pylori is predicted to be involved in uptake of compatible solutes such as choline, L-proline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ProWX belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270330 Cd Length: 267 Bit Score: 251.77 E-value: 1.46e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 235 TITLAGKLGSEPSIITNMYKILIEDETDDTVDVKDGM-GKTSFLFNALKSDDIDGYLEFTGTVLGELTKEDLKSKKEDav 313
Cdd:cd13612 1 TIHIATKPMTEQYILGEMLKQLIEQDTDLKVELTKGVgGGTSNIHPAMVKGEFDLYPEYTGTGWLFVLKKDGTYSEEL-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 314 YQQAKQSLEKKYDMTMLKPMKYNNTYALAVKRDFAKENNIKTIGDLQKVEDKIKPGFTMEFNDRSDGYKAVAKAYGLNLS 393
Cdd:cd13612 79 FDQLQKEYEEKYNLTWLGLYGFNNTYGLAVRKELAEKYNLKTYSDLAKVSNQLVFGAEYDFFEREDGYDALQKAYGFNFK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 394 NVKKMEPKLRYTAVEKGDINLIDAYSTDAELKQYNMVVLKDDKHVFPPYQGAPMFKEKFLKQHPEIKKPLNKLEGKISDE 473
Cdd:cd13612 159 KTVDMDIGLKYQAIESGKVDVINVFTTDGQLSDADIVVLEDDKGFFPSYYAGTVVREETLEKYPELEDVLEKLTGLISDE 238
|
250 260
....*....|....*....|....*....
gi 499595699 474 EMQEMNYKVTVKNEDPYNVAKHYLEKEGL 502
Cdd:cd13612 239 DMAEMNYQVEIEKKDPKDVAKEFLEEKGL 267
|
|
| PBP2_OpuCC_like |
cd13608 |
Substrate-binding protein OpuCC of ABC-type osmoregulatory transporter and related proteins; ... |
235-498 |
3.55e-80 |
|
Substrate-binding protein OpuCC of ABC-type osmoregulatory transporter and related proteins; the type 2 periplasmic-binding protein fold; This subfamily includes the periplasmic substrate-binding protein OpuCC of the ABC transporter OpuC (where Opu is osmoprotectant uptake), which can recognize a broad spectrum of compatible solutes, and its paralog OpuBC that can solely bind choline. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270326 Cd Length: 265 Bit Score: 250.62 E-value: 3.55e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 235 TITLAGKLGSEPSIITNMYKILIEDETDDTVDVKDGMGKTSFLFNALKSDDID-GYLEFTGTVL-GELTKEDLKSKKEda 312
Cdd:cd13608 1 TIRIGSQSTTESQILAEMVKQLIEHYTDLKVELINNLGSSTVQHQAMLNGDANiSAARYTGTDLtGELGMEPIKDPEK-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 313 VYQQAKQSLEKKYDMTMLKPMKYNNTYALAVKRDFAKENNIKTIGDLQKVEDKIKPGFTMEFNDRS-DGYKAVAKAYGLN 391
Cdd:cd13608 79 ALKVVQKEFQKRFDQTWFDSYGFANTYAFMVTKEFAEKYNLKKVSDLKKVADNLKLGVDTSWLNRKgDGYPGFKETYGFD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 392 LSNVKKMEPKLRYTAVEKGDINLIDAYSTDAELKQYNMVVLKDDKHVFPPYQGAPMFKEKFLKQHPEIKKPLNKLEGKIS 471
Cdd:cd13608 159 FGTVYPMQIGLVYDAVASGKMDVVLGYSTDGRIKSYDLVVLEDDKQFFPPYDASPVATNEILKKYPELEEILEKLEGKIS 238
|
250 260
....*....|....*....|....*..
gi 499595699 472 DEEMQEMNYKVTVKNEDPYNVAKHYLE 498
Cdd:cd13608 239 TETMQELNYQVDNDLKEPSVVAKEFLE 265
|
|
| PBP2_Opu_like_2 |
cd13613 |
Substrate-binding domain of putative ABC-type osmoprotectant uptake system; the type 2 ... |
235-497 |
7.36e-72 |
|
Substrate-binding domain of putative ABC-type osmoprotectant uptake system; the type 2 periplasmic-binding protein fold; This group includes the periplasmic substrate-binding component of a putative ABC transport system that is predicted to be involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. The relative substrate preference of this group is not known. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270331 Cd Length: 264 Bit Score: 229.15 E-value: 7.36e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 235 TITLAGKLGSEPSIITNMYKILIEDETDDTVDVKDGMGKTSFLFNALKSDDIDGYLEFTGTVLGELTKEDLkSKKEDAVY 314
Cdd:cd13613 1 RIIIGSKNFTEQVILGELLAQQIEARTDLKVERRFNLGGTFICHQALLSGAIDAYVEYTGTALTAILKQPP-IRDPQRVY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 315 QQAKQSLEKKYDMTMLKPMKYNNTYALAVKRDFAKENNIKTIGDLQKVEDKIKPGFTMEFNDRSDGYKAVAKAYGLNL-S 393
Cdd:cd13613 80 EQVKQLYADRFGLEVMPPLGFENTFAILVRGEDARKLGLKTLSDAAPYTPGWRAGFGYEFLERADGYPGLAKTYGLKFaK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 394 NVKKMEPKLRYTAVEKGDINLIDAYSTDAELKQYNMVVLKDDKHVFPPYQGAPMFKEKFLKQHPEIKKPLNKLEGKISDE 473
Cdd:cd13613 160 TPRVMDLGLLYRALAQKQVDLIAGNSTDGLIAALDLVILEDDRHYFPPYQAVPVVRQATLAKYPELRTAIAELAGKISAE 239
|
250 260
....*....|....*....|....
gi 499595699 474 EMQEMNYKVTVKNEDPYNVAKHYL 497
Cdd:cd13613 240 TMQQMNYQVDGEHRDVAEVAREFL 263
|
|
| PBP2_AfProX_like |
cd13607 |
Substrate-binding protein ProX of ABC-type osmoregulatory transporter from Archaeoglobus ... |
235-498 |
3.00e-69 |
|
Substrate-binding protein ProX of ABC-type osmoregulatory transporter from Archaeoglobus fulgidus and its related proteins; the type 2 periplasmic-binding protein fold; This subfamily includes the periplasmic substrate-binding protein ProX from the hyperthermophilic archaeon Archaeoglobus fulgidus and its related proteins. AfProX is involved in uptake of compatible solutes such as the trimethylammonium compound glycine betaine and the dimethylammonium compound proline betaine, but the relative substrate preference is not known. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. AfProX belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270325 Cd Length: 261 Bit Score: 222.46 E-value: 3.00e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 235 TITLAGKLGSEPSIITNMYKILIEDETDDtVDVKDGMGKTSFLFNALKSDDIDGYLEFTGTVLGELTKEDlKSKKEDAVY 314
Cdd:cd13607 1 TVVIGSKTFTEQYILAEMIAQLLEEAGYP-AEHREGLGGTRVLFEALKSGEIDVYVEYTGTLYAEILKRP-ETWDPAAVL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 315 QQAKQSLEKKyDMTMLKPMKYNNTYALAVKRDFAKENNIKTIGDLQKVEDKIKPGFTMEFNDRSDGYKAVAKAYGLNLSN 394
Cdd:cd13607 79 AELKEALAER-GIVVAGPLGFENTYALAMREDRAEALGIRTISDLLARAPDLRFGFDPEFLDRPDGWPALRRVYGLPFKE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 395 VKKMEPKLRYTAVEKGDINLIDAYSTDAELKQYNMVVLKDDKHVFPPYQGAPMFKEKFLKQHPEIKKPLNKLEGKISDEE 474
Cdd:cd13607 158 VRGLDHTLAYRALKSGQVDVIDAYTTDARIDAYDLRVLEDDRGAFPPYDAVLLYRADLAERAPKAVAALRRLEGRIDADT 237
|
250 260
....*....|....*....|....
gi 499595699 475 MQEMNYKVTVKNEDPYNVAKHYLE 498
Cdd:cd13607 238 MRALNAQVDLEKRSEAEVAAEFLA 261
|
|
| PBP2_QAT_like |
cd13614 |
Substrate-binding domain of quaternary amine ABC-type transporter; the type 2 ... |
235-498 |
3.10e-67 |
|
Substrate-binding domain of quaternary amine ABC-type transporter; the type 2 periplasmic-binding protein fold; This group includes the periplasmic substrate-binding component of a putative quaternary amine ABC transport system that is predicted to be involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. The relative substrate preference of this group is not known. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270332 Cd Length: 264 Bit Score: 217.25 E-value: 3.10e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 235 TITLAGKLGSEPSIITNMYKILIEDETDDtVDVKDGMGKTSFLFNALKSDDIDGYLEFTGTVLGELTKEDlKSKKEDAVY 314
Cdd:cd13614 1 AIRVGSKNFTEQFILGEMYALALEDAGIK-VERKLNLGGTLIAHQALVNGEIDLYPEYTGTALLTVLKGE-PSSDAKQVY 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 315 QQAKQSLEKKYDMTMLKPMKYNNTYALAVKRDFAKENNIKTIGDLQKVEDKIKPGFTMEFNDRSDGYKAVAKAYG-LNLS 393
Cdd:cd13614 79 KTVKDAYAEQFQLTWLEPAPFNNTYALVMTRETAEKYGIKTLSDLAKAAGELVFGGGPEFQDREDGLPGLKAKYGaFDFK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 394 NVKKMEPK-LRYTAVEKGDINLIDAYSTDAELKQYNMVVLKDDKHVFPPYQGAPMFKEKFLKQHPEIKKPLNKLEGKISD 472
Cdd:cd13614 159 EFVQVDPLgLRYQALAQGQIDVAVGFGTDGQIAAYGLVVLEDDKNLFPPYQVAPVVRQDVLDANPKIAEVLNKLSALLDN 238
|
250 260
....*....|....*....|....*.
gi 499595699 473 EEMQEMNYKVTVKNEDPYNVAKHYLE 498
Cdd:cd13614 239 ETMQRLNYEVDGNKREPKDVAREFLK 264
|
|
| PBP2_YehZ |
cd13611 |
Substrate-binding domain YehZ of an osmoregulated ABC-type transporter; the type 2 ... |
235-498 |
5.10e-65 |
|
Substrate-binding domain YehZ of an osmoregulated ABC-type transporter; the type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein YehZ of Clostridium sticklandii is predicted to be involved in uptake of compatible solutes such as choline, L-proline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. YehZ belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270329 Cd Length: 267 Bit Score: 211.67 E-value: 5.10e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 235 TITLAGKLGSEPSIITNMYKILIEDETDDtVDVKDGMGKTSFLFNALKSDDIDGYLEFTGTVLGELTKEDLKSKKEDAVY 314
Cdd:cd13611 1 TITVGSKDFTEQLILGKITVQALQAAGAD-VTDKTNLGGSASARQALENGQVDVYWEYTGTAWITYLGHTEPILDPQEQY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 315 QQAKQsLEKKYDMTMLKPMKYNNTYALAVKRDFAKENNIKTIGDLQKVE---DKIKPGFTMEFNDRSDGYKAVAKAYGLN 391
Cdd:cd13611 80 EAVKD-LDAEKGLVWLDPAPLNNTYALAMREATAEELGITTLSDLALAKlppGDRTFCVDAEFASRPDGLPPLLEAYGFE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 392 L--SNVKKMEPKLRYTAVEKGDINLIDAYSTDAELKQYNMVVLKDDKHVFPPYQGAPMFKEKFLKQHPEIKKPLNKLEGK 469
Cdd:cd13611 159 FprANVRQMDTGLVYTATANGQCDFGEVFTTDGRIKALDLVVLEDDKGFFPAYNAAPVVRTEVLDAHPELAEILNPISAK 238
|
250 260
....*....|....*....|....*....
gi 499595699 470 ISDEEMQEMNYKVTVKNEDPYNVAKHYLE 498
Cdd:cd13611 239 LDNDTMQELNARVDVDGEDPADVARDWLV 267
|
|
| OpuAC |
pfam04069 |
Substrate binding domain of ABC-type glycine betaine transport system; Part of a high affinity ... |
234-499 |
1.76e-59 |
|
Substrate binding domain of ABC-type glycine betaine transport system; Part of a high affinity multicomponent binding-protein-dependent transport system involved in bacterial osmoregulation. This domain is often fused to the permease component of the transporter complex. Family members are often integral membrane proteins or predicted to be attached to the membrane by a lipid anchor. Glycine betaine is involved in protection from high osmolarity environments for example in Bacillus subtilis. The family member OpuBC is closely related, and involved in choline transport. Choline is necessary for the biosynthesis of glycine betaine. L-carnitine is important for osmoregulation in Listeria monocytogenes. Family also contains proteins binding l-proline (ProX), histidine (HisX) and taurine (TauA).
Pssm-ID: 397954 [Multi-domain] Cd Length: 257 Bit Score: 196.78 E-value: 1.76e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 234 DTITLAGKLGSEPSIITNMYKILIEDetDDTVDVKDGMGKTSFLFNALKSDDIDGYL-EFTGTVlgeltkedlkskkeda 312
Cdd:pfam04069 1 KTIVIGSKNWTEQEILANIAAQLLEA--LGYVVELVGLGSSAVLFAALASGDIDLYPeEWTGTT---------------- 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 313 vYQQAKQSLEKKYDMTMLKPMKYNNTYALAVKRDFAKENNIKTIGDLQKVEDKIKPGFTMEFNDRSDGY------KAVAK 386
Cdd:pfam04069 63 -YEAYKKAVEEKLGLLVLGPLGAGNTYGLAVPKYVAEKPGIKSISDLAKPADDLELGFKGEFIGRPDGWgcmrstEGLLK 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 387 AYGLNL-----SNVKKMEPkLRYTAVEKGDINLIDAYSTDAELKQYNMVVLKDDKHVFPP-YQGAPMFKEKFLKQHPEIK 460
Cdd:pfam04069 142 AYGLDKyelveGSEAAMDA-LIYAAYKRGEPDVVYAWTPDWMIKKYDLVVLEDPKGLFPPaYNVVPVVRKGFAEKHPEVA 220
|
250 260 270
....*....|....*....|....*....|....*....
gi 499595699 461 KPLNKLegKISDEEMQEMNYKVTVKNEDPYNVAKHYLEK 499
Cdd:pfam04069 221 AFLNKL--SLDTEDLNELNAQVDVEGKDPEEVAKDWLAE 257
|
|
| PBP2_ProWY |
cd13615 |
Substrate-binding domain of ABC-type osmoregulated transporter; the type 2 periplasmic-binding ... |
235-498 |
5.86e-54 |
|
Substrate-binding domain of ABC-type osmoregulated transporter; the type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein ProWY of Streptococcus thermophilus is predicted to be involved in uptake of compatible solutes such as choline, L-proline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ProWY belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270333 Cd Length: 262 Bit Score: 182.26 E-value: 5.86e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 235 TITLAGKLGSEPSIITNMYKILIEDEtDDTVDVKDGMGkTSFLFNALKSDDIDGYLEFTGTVLGELTKEDLKSKKEDaVY 314
Cdd:cd13615 1 AIRVGSKDFTENLIVAEIYALALEDA-GYKVKRKPNIS-SSVVHQALTSGQIDLYPEYTGTGLLAVLKKEAITDPQK-VY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 315 QQAKQSLEKKYDMTMLKPMKYNNTYALAVKRDFAKENNIKTIGDLQKVEDKIKPGFTMEFNDRSDGYKAVAKAYGL-NLS 393
Cdd:cd13615 78 ATVKDGYAKKFNLVWLDYAPANDGQGLVIRTSVAKKYGIKTISDLQKNASQIRFASQGEFDQREDGLPGLEKVYGKfSFK 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 394 NVKKMEPKLRYTAVEKGDINLIDAYSTDAELKQYNMVVLKDDKHVFPPYQGAPMFKEKFLKQHPEIKKPLNKLEGKISDE 473
Cdd:cd13615 158 STKVYDNGLKYQVLANDKADITPAYTTEGQLDTSKFTLLKDDKHVWPPYNLAPVVRKDVLKANPKIASALNKVSAKLTTK 237
|
250 260
....*....|....*....|....*
gi 499595699 474 EMQEMNYKVTVKNEDPYNVAKHYLE 498
Cdd:cd13615 238 TLTQLNAKVDVDKQEYADVAKDFYL 262
|
|
| PBP2_OsmF |
cd13616 |
Substrate-binding domain OsmF of an osmoregulated ABC-type transporter; the type 2 ... |
235-497 |
4.23e-45 |
|
Substrate-binding domain OsmF of an osmoregulated ABC-type transporter; the type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein OsmF of an ABC transporter (YehZYXW) from Escherichia coli is predicted to be involved in uptake of compatible solutes such as choline, L-proline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. OsmF belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270334 Cd Length: 274 Bit Score: 159.42 E-value: 4.23e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 235 TITLAGKLGSEPSIITNMYKILIEDETDDTVDvKDGMGKTSFLFNALKSDDIDGYLEFTGTVLGELTKEDLK-SKKEDAV 313
Cdd:cd13616 1 PVVVGSKIDTEGALLGNMIVLALEAHGFPVED-KTGLGTTPVVRKALLSGEIDLYPEYTGNGAFFFPEADDPvWKDARKG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 314 YQQAKQSLEKKYDMTMLKPMKYNNTYALAVKRDFAKENNIKTIGDLQKVEDK---IKPGFTMEFNDRSDGYKAVAKAYGL 390
Cdd:cd13616 80 YETVKELDAKNNGLVWLDPAPANNTWAIAVRRDLAEKNNLKTLADLAAYVNEggaFKLAASAEFVERPDALPAFEKAYGF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 391 NLS-----NVKKMEPKLRYTAVEKG--DINLIDAYSTDAELKQYNMVVLKDDKHVFPPYQGAPMFKEKFLKQHPEIKKPL 463
Cdd:cd13616 160 KLSkdqlvILSGGNTAQTEQAAAQGtsGVNAAMAYGTDGAIAALGLVVLEDPKGAQPVYAPAPVVRQEVLEAYPEIAEIL 239
|
250 260 270
....*....|....*....|....*....|....
gi 499595699 464 NKLEGKISDEEMQEMNYKVTVKNEDPYNVAKHYL 497
Cdd:cd13616 240 KPVFATLDLKTLQELNARIAVEGESAEDVARDYL 273
|
|
| PBP2_ProX_like |
cd13606 |
Bacterial substrate-binding protein ProX of ABC-type osmoregulated transporter and its related ... |
245-498 |
1.76e-38 |
|
Bacterial substrate-binding protein ProX of ABC-type osmoregulated transporter and its related proteins; the type 2 periplasmic-binding protein fold; This group includes periplasmic substrate-binding component of ABC transport systems from gram-negative and -positive bacteria that are involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270324 Cd Length: 260 Bit Score: 141.16 E-value: 1.76e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 245 EPSIITNMYKILIEDeTDDTVDVKDGMGKTSFLFNALKSDDIDGYLEFTGTVLGELTKeDLKSKKEDAVYQQAKQSLEKK 324
Cdd:cd13606 11 ESEILAEIYAQALEA-AGVKVTRKLNIGSREVYLPALEDGSIDLVPEYTGNLLQYLDK-DATATDPEEVYAALKAALPEG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 325 ydMTMLKPMKYNNTYALAVKRDFAKENNIKTIGDLQKVEDKIKPGFTMEFNDRSDGYKAVAKAYGLNLSNVKKME--PKL 402
Cdd:cd13606 89 --LEVLDPSPAEDKDALVVTKETAEKYGLKSIADLAPVAGELTLGGPPEFKTRPYGLPGLKEVYGVTFKEFKPLDagGPL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 403 RYTAVEKGDINLIDAYSTDAELKQYNMVVLKDDKHVFPPYQGAPMFKEKFLkqHPEIKKPLNKLEGKISDEEMQEMNYKV 482
Cdd:cd13606 167 TVKALKDGTVQVANIFTTDPAIADNGLVVLEDPKNLFPAQNVVPLVRKAKL--DDKAADALNAVSAKLTTEDLTELNKQV 244
|
250
....*....|....*.
gi 499595699 483 TVKNEDPYNVAKHYLE 498
Cdd:cd13606 245 VGDKADPADVAKEWLK 260
|
|
| ProW |
COG4176 |
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ... |
38-199 |
9.97e-34 |
|
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];
Pssm-ID: 443335 Cd Length: 275 Bit Score: 128.68 E-value: 9.97e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 38 VPLGIALTKTKRLSEVVMNIAAILQTIPSLALLglmIPI---FGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEA 114
Cdd:COG4176 111 IPLGILAARSDRVSRIVRPVLDFMQTMPAFVYL---IPAvmlFGIGKVPGVIATVIFALPPAIRLTNLGIRQVPKELVEA 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 115 AKGIGMKPMRRLTKVELPIAMPVMMAGI-RT-----AMVLIigtatlAALIGAGGLGDLILLGIDRNNTSLILIGAIPAA 188
Cdd:COG4176 188 ADAFGATPWQLLFKVQLPLALPTIMAGVnQTimlalSMVVI------ASMIGAGGLGQEVLRALQRLDIGLGFEAGLAIV 261
|
170
....*....|.
gi 499595699 189 LLAIMFDLILR 199
Cdd:COG4176 262 ILAIILDRITQ 272
|
|
| TauC |
COG0600 |
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ... |
38-204 |
2.31e-30 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];
Pssm-ID: 440365 [Multi-domain] Cd Length: 254 Bit Score: 118.71 E-value: 2.31e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 38 VPLGIALTKTKRLSEVVMNIAAILQTIPSLALLGLMIPIFGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKG 117
Cdd:COG0600 82 VPLGLLLGLSRLLRRLLDPLLVFLRPIPPLALAPLLILWFGIGEASKIFVIFLGAFFPILLNTAAGVRSVDPELLELARS 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 118 IGMKPMRRLTKVELPIAMPVMMAGIRTAMVLIIGTATLAALIGAGG-LGDLILLGIDRNNTSLILIGAIPAALLAIMFDL 196
Cdd:COG0600 162 LGASRWQILRKVVLPAALPYIFTGLRIALGLAWIGLVVAELLGASSgLGYLILDARQLLDTDLVFAAILVIGLLGLLLDL 241
|
....*...
gi 499595699 197 ILRYMEKL 204
Cdd:COG0600 242 LLRLLERR 249
|
|
| PRK10952 |
PRK10952 |
proline/glycine betaine ABC transporter permease ProW; |
39-195 |
2.15e-24 |
|
proline/glycine betaine ABC transporter permease ProW;
Pssm-ID: 236805 Cd Length: 355 Bit Score: 104.40 E-value: 2.15e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 39 PLGIALTKTKRLSEVVMNIAAILQTIPSLALLGLMIPIFGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGI 118
Cdd:PRK10952 166 PLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPPIVRLTILGINQVPADLIEASRSF 245
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499595699 119 GMKPMRRLTKVELPIAMPVMMAGIRTAMVLIIGTATLAALIGAGGLGDLILLGIDRNNTSLILIGAIPAALLAIMFD 195
Cdd:PRK10952 246 GASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQMVLRGIGRLDMGLATVGGVGIVILAIILD 322
|
|
| BPD_transp_1 |
pfam00528 |
Binding-protein-dependent transport system inner membrane component; The alignments cover the ... |
38-203 |
8.21e-24 |
|
Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.
Pssm-ID: 334128 [Multi-domain] Cd Length: 183 Bit Score: 98.14 E-value: 8.21e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 38 VPLGI--ALTKTKRLSEVVMNIAAILQTIPSLALLGLMIP-----IFGIGRVPAIIALVVYALLPILRNTYTGIKEVDPS 110
Cdd:pfam00528 2 IPLGIiaALRRGRRLDRLLRPLIDLLQALPSFVLAILLVViailsILGHGILPAIILALLGWAGYARLIRRAALRSLPSD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 111 LIEAAKGIGMKPMRRLTKVELPIAMPVMMAGIRTAMVLIIGTATLAALIGA-----GGLGDLILLGIDRNNTSLILIGAI 185
Cdd:pfam00528 82 LVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSwpglgLLLIEAILGYDYPEIQGPVLAAAL 161
|
170
....*....|....*...
gi 499595699 186 PAALLAIMFDLILRYMEK 203
Cdd:pfam00528 162 ILLLLNLLVDILQRLLDP 179
|
|
| TM_PBP2 |
cd06261 |
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ... |
38-194 |
5.15e-20 |
|
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.
Pssm-ID: 119394 [Multi-domain] Cd Length: 190 Bit Score: 87.72 E-value: 5.15e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 38 VPLGIALT-KTKRLSEVVMNIAAILQTIPSLALLGLMIPIFGIGRV---------PAIIALVVYALLPILRNTYTGIKEV 107
Cdd:cd06261 20 LLLGIILArKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGwgilpglglPALILALLLIAPFARLIRRAALESI 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 108 DPSLIEAAKGIGMKPMRRLTKVELPIAMPVMMAGIRTAMVLIIGTATLAALIGAGGLGDLILLGIDRNNTSLILIGAIPA 187
Cdd:cd06261 100 PKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPGTGLLLIFAILFPGDLGVAA 179
|
....*..
gi 499595699 188 ALLAIMF 194
Cdd:cd06261 180 AVALILL 186
|
|
| ssuC |
PRK11365 |
aliphatic sulfonate ABC transporter permease SsuC; |
60-204 |
2.18e-13 |
|
aliphatic sulfonate ABC transporter permease SsuC;
Pssm-ID: 183100 Cd Length: 263 Bit Score: 70.35 E-value: 2.18e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 60 ILQTIPSLALLGLMIPIFGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGIGMKPMRRLTKVELPIAMPVMM 139
Cdd:PRK11365 103 MLRNVPHLALIPLVILWFGIDESAKIFLVALGTLFPIYINTWHGIRNIDRGLVEMARSYGLSGIPLFIHVILPGALPSIM 182
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499595699 140 AGIRTAMVLIIGTATLAALIGAGGLGDLILLGIDRN-NTSLILIGAIPAALLAIMFDLILRYMEKL 204
Cdd:PRK11365 183 VGVRFALGLMWLTLIVAETISANSGIGYLAMNAREFlQTDVVVVAIILYALLGKLADVSAQLLERL 248
|
|
| MetP |
COG2011 |
ABC-type methionine transport system, permease component [Amino acid transport and metabolism]; ... |
39-161 |
4.17e-13 |
|
ABC-type methionine transport system, permease component [Amino acid transport and metabolism];
Pssm-ID: 441614 Cd Length: 220 Bit Score: 68.54 E-value: 4.17e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 39 PLGIALTKTKR--------LSEVVMNIAAILQTIPSLALLGLMIP----IFG--IGRVPAIIALVVYALLPILRNTYTGI 104
Cdd:COG2011 36 PLGVLLVLTRPggllpnpvLYRVLGVIVNIFRSIPFIILLVALIPltrlIVGtsIGTTAAIVPLTIAAIPFFARLVENAL 115
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 499595699 105 KEVDPSLIEAAKGIGMKPMRRLTKVELPIAMPVMMAGIRTAMVLIIGTATLAALIGA 161
Cdd:COG2011 116 REVDPGVIEAAQAMGASPWQIIFKVLLPEALPSLILGLTVTLISLIGYSAMAGAVGG 172
|
|
| FbpB |
COG1178 |
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; |
38-160 |
3.11e-11 |
|
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
Pssm-ID: 440791 [Multi-domain] Cd Length: 538 Bit Score: 65.57 E-value: 3.11e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 38 VPLGIALTKTK-RLSEVVMNIAAILQTIPSLAL-LGLMIP---IFGIGRVPAIIALV-VYAL--LPI-LRNTYTGIKEVD 108
Cdd:COG1178 359 LLLAYLVRRRRgRLARLLDRLAMLPYAVPGIVLgLGLLLLfnrPLPLLLYGTLAILVlAYVVrfLPFaLRSLEAALAQID 438
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 499595699 109 PSLIEAAKGIGMKPMRRLTKVELPIAMPVMMAGIRTAMVLIIGTATLAALIG 160
Cdd:COG1178 439 PSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKELSATLLLR 490
|
|
| PRK10160 |
PRK10160 |
taurine ABC transporter permease TauC; |
38-203 |
1.11e-09 |
|
taurine ABC transporter permease TauC;
Pssm-ID: 182276 Cd Length: 275 Bit Score: 59.41 E-value: 1.11e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 38 VPLGIALTKTKRLSEVVMNIAAILQTIPSLALLGLMIPIFGIGRVPAI--IALVVYAllPILRNTYTGIKEVDPSLIEAA 115
Cdd:PRK10160 99 IPVGIAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKIllIYLAIFA--PVAMSALAGVKSAQQVRIRAA 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 116 KGIGMKPMRRLTKVELPIAMPVMMAGIRTAmvLIIGTATLAA--LIGAGGLGDLILLGIDRN-NTSLILIGAIPAALLAI 192
Cdd:PRK10160 177 QSLGASRAQVLWFVILPGALPEILTGLRIG--LGVGWSTLVAaeLIAATRGLGFMVQSAGEFlATDVVLAGIAVIAIIAF 254
|
170
....*....|.
gi 499595699 193 MFDLILRYMEK 203
Cdd:PRK10160 255 LLELGLRALQR 265
|
|
| FbpB |
COG1178 |
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; |
68-160 |
1.53e-08 |
|
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
Pssm-ID: 440791 [Multi-domain] Cd Length: 538 Bit Score: 57.09 E-value: 1.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 68 ALLGLMIP-IFGIGrvPAIIALVVYaLLP-ILRNTYTGIKEVDPSLIEAAKGIGMKPMRRLTKVELPIAMPVMMAGIRTA 145
Cdd:COG1178 127 ALFGLEPPdIYGLG--GIILVLVLF-NYPyVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLV 203
|
90
....*....|....*
gi 499595699 146 MVLIIGTATLAALIG 160
Cdd:COG1178 204 FLLCLADFGTPLVLG 218
|
|
| PotC |
COG1177 |
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ... |
38-141 |
2.37e-08 |
|
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];
Pssm-ID: 440790 [Multi-domain] Cd Length: 262 Bit Score: 55.12 E-value: 2.37e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 38 VPLGIALTKTK-RLSEVVMNIAAILQTIPS----LALLGLMIPI-FGIGRVPAIIALVVYALlPI-LRNTYTGIKEVDPS 110
Cdd:COG1177 82 TPAALALARYRfRGRRLLLALLLLPLVVPGivlgVALLLLFSALgLSGGLWGLILAHVVFTL-PFvVLVVLARLQGFDPS 160
|
90 100 110
....*....|....*....|....*....|.
gi 499595699 111 LIEAAKGIGMKPMRRLTKVELPIAMPVMMAG 141
Cdd:COG1177 161 LEEAARDLGASPWQTFRRVTLPLIAPGILAG 191
|
|
| PRK10782 |
PRK10782 |
D-methionine ABC transporter permease MetI; |
38-161 |
6.37e-08 |
|
D-methionine ABC transporter permease MetI;
Pssm-ID: 182726 Cd Length: 217 Bit Score: 53.20 E-value: 6.37e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 38 VPLGIALTKTK--------RLSEVVMNIAAILQTIPSLALLGLMIP----IFG--IGRVPAIIALVVYALLPILRNTYTG 103
Cdd:PRK10782 32 LPVGVLLYVTRpgqiianaKLYRTLSALVNIFRSIPFIILLVWMIPftrvIVGtsIGLQAAIVPLTVGAAPFIARMVENA 111
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 499595699 104 IKEVDPSLIEAAKGIGMKPMRRLTKVELPIAMPVMMAGIRTAMVLIIGTATLAALIGA 161
Cdd:PRK10782 112 LLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGYSAMGGAVGA 169
|
|
| PhnE |
COG3639 |
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ... |
13-151 |
2.97e-07 |
|
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];
Pssm-ID: 442856 [Multi-domain] Cd Length: 244 Bit Score: 51.62 E-value: 2.97e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 13 GEVLTTILEHIQISFIALLIAILIAVPLGIA----LTKTKRLSEVVMNIAAILQTIPSLALLGLMIPIFGIGRVPAIIAL 88
Cdd:COG3639 47 PDLLSALLETLAIALLGTLLGAVLALPLAFLaarnLAPNPWVRLLARRLLNVLRAIPELVWALIFVAAVGLGPFAGVLAL 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 89 VVYallpilrntYTG---------IKEVDPSLIEAAKGIGMKPMRRLTKVELPIAMPVMMA--------GIRTAMVL-II 150
Cdd:COG3639 127 AIH---------TIGflgklfaeaIEEIDPGPVEALRATGASRLQVIRYGVLPQVLPQFLSytlyrfeiNIRAATVLgLV 197
|
.
gi 499595699 151 G 151
Cdd:COG3639 198 G 198
|
|
| PotB |
COG1176 |
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ... |
67-160 |
3.93e-07 |
|
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];
Pssm-ID: 440789 [Multi-domain] Cd Length: 287 Bit Score: 51.69 E-value: 3.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 67 LALLGLMIPIFGIGR-VPAIIALVVYALLP--ILrNTYTGIKEVDPSLIEAAKGIGMKPMRRLTKVELPIAMPVMMAGIR 143
Cdd:COG1176 138 LLALGLIDEPLRLLYtEFAVVIGLVYVYLPfmVL-PLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSL 216
|
90
....*....|....*..
gi 499595699 144 TAMVLIIGTATLAALIG 160
Cdd:COG1176 217 LVFIPALGAFVTPALLG 233
|
|
| HisM |
COG0765 |
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ... |
52-160 |
5.00e-07 |
|
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];
Pssm-ID: 440528 [Multi-domain] Cd Length: 218 Bit Score: 50.46 E-value: 5.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 52 EVVMNIAAILQtipsLALLGLMIPIFGIgRVP----AIIALVVYA---LLPILRntyTGIKEVDPSLIEAAKGIGMKPMR 124
Cdd:COG0765 60 EFFRGTPLLVQ----LFFIYFGLPLLGI-DLSpfvaAVIALTLNSaayLAEIVR---AGIQSVPKGQWEAARALGLSRWQ 131
|
90 100 110
....*....|....*....|....*....|....*.
gi 499595699 125 RLTKVELPIAMPVMMAGIRTAMVLIIGTATLAALIG 160
Cdd:COG0765 132 TMRRIILPQALRIILPPLGNEFISLLKDTSLVSVIG 167
|
|
| PhnE |
TIGR01097 |
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ... |
1-151 |
7.00e-07 |
|
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]
Pssm-ID: 273441 [Multi-domain] Cd Length: 250 Bit Score: 50.62 E-value: 7.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 1 MSELFSTLNDRKGEVLTTILEHIQISFIALLIAILIAVPLGI----ALTKTKRLSEVVMNIAAILQTIPSLALLGLMIPI 76
Cdd:TIGR01097 42 LGRMFPPDWSYLPRILKALLETLAMAILGTVLAAVLAVPLALlaarNITPSPWLYGLARLLLNFLRAIPELVWALIFVAA 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 77 FGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGIGMKPMRRLTKVELPIAMPVMMA--------GIRTAMVL 148
Cdd:TIGR01097 122 VGLGPFAGVLALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQVLPQFLSytlyrfeiNVRAAAVL 201
|
....
gi 499595699 149 -IIG 151
Cdd:TIGR01097 202 gLVG 205
|
|
| potB |
PRK09497 |
spermidine/putrescine ABC transporter membrane protein; Reviewed |
84-160 |
1.32e-04 |
|
spermidine/putrescine ABC transporter membrane protein; Reviewed
Pssm-ID: 181910 Cd Length: 285 Bit Score: 43.91 E-value: 1.32e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499595699 84 AIIALVVYALLP-ILRNTYTGIKEVDPSLIEAAKGIGMKPMRRLTKVELPIAMPVMMAGIRTAMVLIIGTATLAALIG 160
Cdd:PRK09497 152 AVIIGLVYILLPfMVLPLYSSIEKLDKPLLEAARDLGANKLQTFIRIIIPLTMPGIIAGCLLVLLPAMGMFYVSDLLG 229
|
|
| PRK15050 |
PRK15050 |
2-aminoethylphosphonate transport system permease PhnU; Provisional |
76-150 |
2.43e-04 |
|
2-aminoethylphosphonate transport system permease PhnU; Provisional
Pssm-ID: 237888 [Multi-domain] Cd Length: 296 Bit Score: 43.07 E-value: 2.43e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499595699 76 IFGIGRVpaIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGIGMKPMRRLTKVELPIAMPVMMAGirTAMVLII 150
Cdd:PRK15050 158 LYSPGGV--ILAEITFYTPFVVRPLLAAFAQLDARQLEAAASLGASPWRVARRVILPEAWPALAAG--GSLCLLL 228
|
|
| potC |
PRK09500 |
spermidine/putrescine ABC transporter membrane protein; Reviewed |
53-141 |
2.95e-03 |
|
spermidine/putrescine ABC transporter membrane protein; Reviewed
Pssm-ID: 236542 [Multi-domain] Cd Length: 256 Bit Score: 39.58 E-value: 2.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499595699 53 VVMNIAAILQTIPSLALLglMIPIFGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGIGMKPMRRLTKVELP 132
Cdd:PRK09500 101 VVMMSPDIVMAISLLVLF--MLLGIQLGFWSLLFAHITFCLPFVVVTVYSRLKGFDVRMLEAAKDLGASEFTILRKIILP 178
|
....*....
gi 499595699 133 IAMPVMMAG 141
Cdd:PRK09500 179 LALPAVAAG 187
|
|
| |
