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Concise Results
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MULTISPECIES: sodium/proton antiporter NhaB [Photorhabdus]
Protein Classification
Na(+)/H(+) antiporter NhaB ( domain architecture ID 10013265 )
Na(+)/H(+) antiporter NhaB is involved in regulation of intracellular pH under alkaline conditions
List of domain hits
Name
Accession
Description
Interval
E-value
nhaB
PRK09547 sodium/proton antiporter NhaB;
1-512
0e+00
sodium/proton antiporter NhaB;
Pssm-ID: 181942
Cd Length: 513
Bit Score: 955.88
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 1 ME T S ILKTAV KNFLG N SPDWYKLAII I FLIINPLIFF FIN PFV T GWLLV I EFIFTLAMALKCYPLQPGGLLAIEAV I IGM 80
Cdd:PRK09547 1 ME I S LGRAFW KNFLG Q SPDWYKLAII A FLIINPLIFF LVS PFV A GWLLV A EFIFTLAMALKCYPLQPGGLLAIEAV F IGM 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 81 TSP QQ V G HEIA N NLEV V LLL I FMVAGIYFMKQLLLF A FTKLLLSI K SK RM L A LAFCLA S AFLSAFLDALTVIAVVISV SL 160
Cdd:PRK09547 81 TSP EH V Y HEIA A NLEV L LLL M FMVAGIYFMKQLLLF I FTKLLLSI R SK ML L S LAFCLA A AFLSAFLDALTVIAVVISV AV 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 161 GFY S IY NNFITDQ -- NDVINAKH D N HID t AKKKQT LEQFRAFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAK NVN W D F V 238
Cdd:PRK09547 161 GFY G IY HRVASGK gf SEDHDLTD D S HID - ELYRED LEQFRAFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAK QAG W H F G 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 239 T FF I RMAP I T L PV F ICGLL V C F LVE H F KL FGYG TE LPE R VRQVL E DYD KKTS AKRT HKE KA Q LI A QALIG I WLIVALA F H 318
Cdd:PRK09547 240 E FF L RMAP V T V PV L ICGLL T C L LVE K F RW FGYG AK LPE K VRQVL Q DYD DQER AKRT RQD KA K LI V QALIG V WLIVALA L H 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 319 LAEVGLIGLSVIIL T T S F C G I T E EHA L GKAFEEALPFTALLTVFF SI VAVI V DQ Q LF T P F IQFVLQ V SE TS QLSLFY LF N 398
Cdd:PRK09547 320 LAEVGLIGLSVIIL A T A F T G V T D EHA I GKAFEEALPFTALLTVFF AV VAVI I DQ H LF A P I IQFVLQ A SE HA QLSLFY IA N 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 399 GLLSS V SDNVFVGTVYINEA RT A MQE G L IS H KQFE Y LAVAINTGTNLPSVATPNGQAAFLFLLTS T L S PLIRLSYGRMV I 478
Cdd:PRK09547 400 GLLSS I SDNVFVGTVYINEA KA A LES G A IS R KQFE L LAVAINTGTNLPSVATPNGQAAFLFLLTS A L A PLIRLSYGRMV W 479
490 500 510
....*....|....*....|....*....|....
gi 499459322 479 MALPYTIV M TLVGLL C VEF L L I PVT DMMVHW G L I 512
Cdd:PRK09547 480 MALPYTIV L TLVGLL A VEF T L A PVT EWFYQM G W I 513
Name
Accession
Description
Interval
E-value
nhaB
PRK09547 sodium/proton antiporter NhaB;
1-512
0e+00
sodium/proton antiporter NhaB;
Pssm-ID: 181942
Cd Length: 513
Bit Score: 955.88
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 1 ME T S ILKTAV KNFLG N SPDWYKLAII I FLIINPLIFF FIN PFV T GWLLV I EFIFTLAMALKCYPLQPGGLLAIEAV I IGM 80
Cdd:PRK09547 1 ME I S LGRAFW KNFLG Q SPDWYKLAII A FLIINPLIFF LVS PFV A GWLLV A EFIFTLAMALKCYPLQPGGLLAIEAV F IGM 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 81 TSP QQ V G HEIA N NLEV V LLL I FMVAGIYFMKQLLLF A FTKLLLSI K SK RM L A LAFCLA S AFLSAFLDALTVIAVVISV SL 160
Cdd:PRK09547 81 TSP EH V Y HEIA A NLEV L LLL M FMVAGIYFMKQLLLF I FTKLLLSI R SK ML L S LAFCLA A AFLSAFLDALTVIAVVISV AV 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 161 GFY S IY NNFITDQ -- NDVINAKH D N HID t AKKKQT LEQFRAFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAK NVN W D F V 238
Cdd:PRK09547 161 GFY G IY HRVASGK gf SEDHDLTD D S HID - ELYRED LEQFRAFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAK QAG W H F G 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 239 T FF I RMAP I T L PV F ICGLL V C F LVE H F KL FGYG TE LPE R VRQVL E DYD KKTS AKRT HKE KA Q LI A QALIG I WLIVALA F H 318
Cdd:PRK09547 240 E FF L RMAP V T V PV L ICGLL T C L LVE K F RW FGYG AK LPE K VRQVL Q DYD DQER AKRT RQD KA K LI V QALIG V WLIVALA L H 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 319 LAEVGLIGLSVIIL T T S F C G I T E EHA L GKAFEEALPFTALLTVFF SI VAVI V DQ Q LF T P F IQFVLQ V SE TS QLSLFY LF N 398
Cdd:PRK09547 320 LAEVGLIGLSVIIL A T A F T G V T D EHA I GKAFEEALPFTALLTVFF AV VAVI I DQ H LF A P I IQFVLQ A SE HA QLSLFY IA N 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 399 GLLSS V SDNVFVGTVYINEA RT A MQE G L IS H KQFE Y LAVAINTGTNLPSVATPNGQAAFLFLLTS T L S PLIRLSYGRMV I 478
Cdd:PRK09547 400 GLLSS I SDNVFVGTVYINEA KA A LES G A IS R KQFE L LAVAINTGTNLPSVATPNGQAAFLFLLTS A L A PLIRLSYGRMV W 479
490 500 510
....*....|....*....|....*....|....
gi 499459322 479 MALPYTIV M TLVGLL C VEF L L I PVT DMMVHW G L I 512
Cdd:PRK09547 480 MALPYTIV L TLVGLL A VEF T L A PVT EWFYQM G W I 513
NhaB
COG3067 Na+/H+ antiporter NhaB [Energy production and conversion, Inorganic ion transport and ...
3-499
0e+00
Na+/H+ antiporter NhaB [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 442301
Cd Length: 498
Bit Score: 914.64
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 3 T S ILKTAV KNFLG N SPDWYKL A I II FLIINP LI FF FIN PFV T GWLLV I EFIFTLAMALKCYPLQPGGLLAIEAV I IGMTS 82
Cdd:COG3067 1 M S LGRAFA KNFLG Q SPDWYKL T I LA FLIINP IL FF TVG PFV A GWLLV A EFIFTLAMALKCYPLQPGGLLAIEAV L IGMTS 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 83 P QQ V G HE IAN NLEV V LLL I FMVAGIYFMKQLLLF A FTKLLL S I K SK RM L A LAFCLA S AFLSAFLDALTV I AV V ISV SL GF 162
Cdd:COG3067 81 P EH V Y HE VEA NLEV I LLL M FMVAGIYFMKQLLLF V FTKLLL G I R SK IL L S LAFCLA A AFLSAFLDALTV T AV I ISV AV GF 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 163 YS I Y NNFITDQN -- D VINAKH D N H I D t AKKKQT LEQFRAFLRSL M MHA G VGTALGGVMTMVGEPQNLIIA KNVN WDF VT F 240
Cdd:COG3067 161 YS V Y HKVASGKG fh D DHDHTD D D H V D - ELHRED LEQFRAFLRSL L MHA A VGTALGGVMTMVGEPQNLIIA EQAG WDF GE F 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 241 F I RMAP I T L PV F ICGLL V C F L V E H FK L FGYG TE LPE R VRQ V L E D Y D KKTS AKRT HKEK A Q LI A QA L I GI WLIV A LA F HLA 320
Cdd:COG3067 240 F L RMAP V T I PV L ICGLL T C V L L E K FK W FGYG AK LPE S VRQ I L A D F D REED AKRT KQDR A K LI V QA I I AV WLIV G LA L HLA 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 321 EVGLIGLSVIIL T T S F C G I T E EHA L GKAFEEALPFTALL T VFF SI VAVI V DQ Q LFTP F IQ F VL QVSETS QL SL FYL F NGL 400
Cdd:COG3067 320 EVGLIGLSVIIL A T A F N G V T D EHA I GKAFEEALPFTALL V VFF AV VAVI I DQ H LFTP I IQ W VL SLEGEQ QL AM FYL A NGL 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 401 LS SV SDNVFV G TVYINE ART A MQE G L I SHK QF EY LAVAINTGTNLPSVATPNGQAAFLFLLTS T L S PLIRLSYGRMV I MA 480
Cdd:COG3067 400 LS MI SDNVFV A TVYINE VKA A LDA G T I TRE QF DL LAVAINTGTNLPSVATPNGQAAFLFLLTS A L A PLIRLSYGRMV W MA 479
490
....*....|....*....
gi 499459322 481 LPYTIV M TLVGLL C VEFLL 499
Cdd:COG3067 480 LPYTIV L TLVGLL A VEFLL 498
NhaB
TIGR00774 Na+/H+ antiporter NhaB; These proteins are members of the NhaB Na+:H+ Antiporter (NhaB) Family ...
1-513
0e+00
Na+/H+ antiporter NhaB; These proteins are members of the NhaB Na+:H+ Antiporter (NhaB) Family (TC 2.A.34). The only characterised member of this family is the Escherichia coli NhaB protein, which has 12 GES predicted transmembrane regions, and catalyses sodium/proton exchange. Unlike NhaA this activity is not pH dependent. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129856
Cd Length: 515
Bit Score: 738.99
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 1 ME T S ILKTAV KNFLG N SPDWYKLAII I FLIINP LI FF F I N PFV T GWLLV I EFIFTLAMALKCYPLQPGGLLAIEA VI IGM 80
Cdd:TIGR00774 1 ME I S LGNAFI KNFLG K SPDWYKLAII A FLIINP IV FF L I S PFV A GWLLV A EFIFTLAMALKCYPLQPGGLLAIEA IA IGM 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 81 TS PQQ V G HE IAN N L EV V LLL I FMVAGIYFMKQLLLF A FTKLLL S I K SK RM L A LAFC L A S AFLSAFLDALTV I AVVISV SL 160
Cdd:TIGR00774 81 TS AAH V K HE LVA N I EV L LLL V FMVAGIYFMKQLLLF I FTKLLL G I R SK TL L S LAFC F A A AFLSAFLDALTV V AVVISV AV 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 161 GFY S IY NNFITDQN - DVINAKH D NH I DT a KKKQT LE Q FRAFLRSLMMHAGVGTALGGVMTMVGEPQNLIIA KNVN W D F VT 239
Cdd:TIGR00774 161 GFY G IY HKVASGNP i GDHDHTD D DT I TE - LTRDD LE N FRAFLRSLMMHAGVGTALGGVMTMVGEPQNLIIA DQAG W L F GE 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 240 FF I RM A P I TLPVFICGLL V C F LVE HF K L FGYG TE LP ER VRQ V L E D Y D KKTSAK RT HKE K AQ L IA QALI GI WLIVALA F HL 319
Cdd:TIGR00774 240 FF L RM S P V TLPVFICGLL T C A LVE KL K V FGYG EK LP DN VRQ I L V D F D REERKT RT NQD K IK L WV QALI AV WLIVALA L HL 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 320 A E VGLIGLSVIIL T TSF C G I T E EH AL GKAFEE A LPFTALL T VFFS I VAVI V DQ Q LF T P F I Q FVL QVS E TS QL S LFY L FNG 399
Cdd:TIGR00774 320 A A VGLIGLSVIIL A TSF T G V T D EH SI GKAFEE S LPFTALL A VFFS V VAVI I DQ E LF S P I I D FVL AAE E KT QL A LFY V FNG 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 400 LLSS V SDNVFVGTVYINEA RT A MQ EGLI SHK QFE Y LAVAINTGTNLPSVATPNGQAAFLFLLTS T L S PLIRLSYGRMV I M 479
Cdd:TIGR00774 400 LLSS I SDNVFVGTVYINEA KA A LT EGLI TRE QFE L LAVAINTGTNLPSVATPNGQAAFLFLLTS A L A PLIRLSYGRMV Y M 479
490 500 510
....*....|....*....|....*....|....
gi 499459322 480 ALPYTIV MTL VGLL CV EF L L I P V T DMMVHW G L I A 513
Cdd:TIGR00774 480 ALPYTIV LAI VGLL GI EF F L E P A T AWFYDA G W I L 513
NhaB
pfam06450 Bacterial Na+/H+ antiporter B (NhaB); This family consists of several bacterial Na+/H+ ...
1-513
0e+00
Bacterial Na+/H+ antiporter B (NhaB); This family consists of several bacterial Na+/H+ antiporter B (NhaB) proteins. The exact function of this family is unknown.
Pssm-ID: 283984
Cd Length: 515
Bit Score: 735.51
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 1 M ETSILKTAV KNFLG N SPDWYKLAII I FLIINP LI FF F I N PFV T GWLLV I EFIFTLAMALKCYPLQPGGLLAIEAV I IGM 80
Cdd:pfam06450 1 M PITNGQAFI KNFLG A SPDWYKLAII V FLIINP IV FF L I S PFV A GWLLV A EFIFTLAMALKCYPLQPGGLLAIEAV A IGM 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 81 TS PQQ V G HEI AN NLEV V LLL I FMVAGIYFMKQLLLF A FTKLLL S I K SK RM L A LAFC L A S AFLSAFLDALTV I AV V ISV SL 160
Cdd:pfam06450 81 TS AKH V K HEI MA NLEV L LLL V FMVAGIYFMKQLLLF I FTKLLL K I R SK IL L S LAFC F A A AFLSAFLDALTV V AV I ISV AV 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 161 GFY S IY NNFITDQ N DVINAK H -- D NH I DT a KKKQT LE Q FR A FLRSLMMHAGVGTALGGVMTMVGEPQNLIIA KNVN W D F V 238
Cdd:pfam06450 161 GFY G IY HKVASGN N LIDDHD H td D RK I IE - LQHEI LE K FR G FLRSLMMHAGVGTALGGVMTMVGEPQNLIIA EQAG W N F G 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 239 T FF I RM A P I T L PVFICGLL V CFLVE H F K LFGYG TE LP ER VR QV L E D Y D KKTSA KRT HKE K AQ LI A QA L IG I WLIV A LA F H 318
Cdd:pfam06450 240 E FF L RM S P V T V PVFICGLL T CFLVE K F R LFGYG EK LP DE VR KI L S D F D RTERE KRT NQD K IK LI V QA I IG V WLIV G LA L H 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 319 LA E VGLIGLSVIIL T TSF C G I T E EHA L GKAFEE A LPFTALL T VFFS I VAVI V DQQLF T P F IQFVL QVS E TS QL S LFY L FN 398
Cdd:pfam06450 320 LA A VGLIGLSVIIL A TSF T G V T D EHA I GKAFEE S LPFTALL A VFFS V VAVI I DQQLF S P I IQFVL SAE E NT QL A LFY I FN 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 399 GLLSS V SDNVFVGTVYINEA RT A MQE G L I SHK QFE Y LAVAINTGTNLPSVATPNGQAAFLFLLTS T L S PLIRLSYGRMV I 478
Cdd:pfam06450 400 GLLSS I SDNVFVGTVYINEA KA A LTN G V I TRH QFE L LAVAINTGTNLPSVATPNGQAAFLFLLTS A L A PLIRLSYGRMV W 479
490 500 510
....*....|....*....|....*....|....*
gi 499459322 479 MALPYTIV MTL VGLL CV EF L L I P V T DMMVHW G L I A 513
Cdd:pfam06450 480 MALPYTIV LSI VGLL AI EF I L E P A T IWFYDL G W I L 514
ArsB_NhaD_permease
cd00625 Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ...
70-493
3.69e-11
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain]
Cd Length: 396
Bit Score: 64.96
E-value: 3.69e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 70 L L A IEA V II G MT SP QQVGHE I ANNLEVV L LLIFMVAGIYFMKQ L LLFAFT KL LLSI K SK R M L A L AFC L AS A F LSAF L -- D 147
Cdd:cd00625 17 L G A VLL V LL G VV SP KEALSA I DWETILL L FGMMILSAALEETG L FDRLAA KL ARAS K GS R R L L L LLM L LT A A LSAF F sn D 96
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 148 A LT V IAVV I SVS L gfysiynnfitdqndvinakhdnhidtakkkq TLEQFRAFLRS L MMHAGVGTAL GG VM T MV G E P Q NL 227
Cdd:cd00625 97 A TA V LLTP I VLA L -------------------------------- LRKLGLSPPVP L LLALAFAANI GG AA T PI G N P P NL 144
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 228 IIA KNVNWD F VT F FIR MAP IT L PVFICG L LVCF L VEHF KL FGYGTELPERVRQV L EDYDKKTSAKRT hkekaq LIAQA L I 307
Cdd:cd00625 145 IIA SLSGLG F LD F LAF MAP PA L GLLLLL L GLLY L LFRK KL LLPDEDKLTVLAEP L PARPLLKKFLLL ------ ALLLL L L 218
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 308 GIW L IVA L AFHLAEVG L IG L SVII L TT sf C G ITE E HA L GKAFEEA L P F T A L L T V FFSIVAVIVDQQLFTPFIQFVLQVSE 387
Cdd:cd00625 219 FVL L FFF L IPLGLIAL L GA L LLLL L LV -- R G LDP E EV L KSVDWGT L L F F A G L F V LVGALESTGLLEWLAELLVALVGLPP 296
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 388 TSQ L S L FY L FNG LLS SVSD NV FVGTVYINE A RTA mqegli SHKQFEY LA V A I nt G TN L PSVA T PN G QA A F L FL L TSTLSP 467
Cdd:cd00625 297 LAA L L L IG L LSA LLS NFIS NV PTVALLLPI A ASL ------ APPEPAW LA L A L -- G ST L GGNL T LI G SL A N L IP L GAAENA 368
410 420
....*....|....*....|....*.
gi 499459322 468 LIRL S Y G RMVIMA LP Y T IVMTL V G LL 493
Cdd:cd00625 369 GVGI S F G EFLKVG LP L T LLSLV V S LL 394
Name
Accession
Description
Interval
E-value
nhaB
PRK09547 sodium/proton antiporter NhaB;
1-512
0e+00
sodium/proton antiporter NhaB;
Pssm-ID: 181942
Cd Length: 513
Bit Score: 955.88
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 1 ME T S ILKTAV KNFLG N SPDWYKLAII I FLIINPLIFF FIN PFV T GWLLV I EFIFTLAMALKCYPLQPGGLLAIEAV I IGM 80
Cdd:PRK09547 1 ME I S LGRAFW KNFLG Q SPDWYKLAII A FLIINPLIFF LVS PFV A GWLLV A EFIFTLAMALKCYPLQPGGLLAIEAV F IGM 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 81 TSP QQ V G HEIA N NLEV V LLL I FMVAGIYFMKQLLLF A FTKLLLSI K SK RM L A LAFCLA S AFLSAFLDALTVIAVVISV SL 160
Cdd:PRK09547 81 TSP EH V Y HEIA A NLEV L LLL M FMVAGIYFMKQLLLF I FTKLLLSI R SK ML L S LAFCLA A AFLSAFLDALTVIAVVISV AV 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 161 GFY S IY NNFITDQ -- NDVINAKH D N HID t AKKKQT LEQFRAFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAK NVN W D F V 238
Cdd:PRK09547 161 GFY G IY HRVASGK gf SEDHDLTD D S HID - ELYRED LEQFRAFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAK QAG W H F G 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 239 T FF I RMAP I T L PV F ICGLL V C F LVE H F KL FGYG TE LPE R VRQVL E DYD KKTS AKRT HKE KA Q LI A QALIG I WLIVALA F H 318
Cdd:PRK09547 240 E FF L RMAP V T V PV L ICGLL T C L LVE K F RW FGYG AK LPE K VRQVL Q DYD DQER AKRT RQD KA K LI V QALIG V WLIVALA L H 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 319 LAEVGLIGLSVIIL T T S F C G I T E EHA L GKAFEEALPFTALLTVFF SI VAVI V DQ Q LF T P F IQFVLQ V SE TS QLSLFY LF N 398
Cdd:PRK09547 320 LAEVGLIGLSVIIL A T A F T G V T D EHA I GKAFEEALPFTALLTVFF AV VAVI I DQ H LF A P I IQFVLQ A SE HA QLSLFY IA N 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 399 GLLSS V SDNVFVGTVYINEA RT A MQE G L IS H KQFE Y LAVAINTGTNLPSVATPNGQAAFLFLLTS T L S PLIRLSYGRMV I 478
Cdd:PRK09547 400 GLLSS I SDNVFVGTVYINEA KA A LES G A IS R KQFE L LAVAINTGTNLPSVATPNGQAAFLFLLTS A L A PLIRLSYGRMV W 479
490 500 510
....*....|....*....|....*....|....
gi 499459322 479 MALPYTIV M TLVGLL C VEF L L I PVT DMMVHW G L I 512
Cdd:PRK09547 480 MALPYTIV L TLVGLL A VEF T L A PVT EWFYQM G W I 513
NhaB
COG3067 Na+/H+ antiporter NhaB [Energy production and conversion, Inorganic ion transport and ...
3-499
0e+00
Na+/H+ antiporter NhaB [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 442301
Cd Length: 498
Bit Score: 914.64
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 3 T S ILKTAV KNFLG N SPDWYKL A I II FLIINP LI FF FIN PFV T GWLLV I EFIFTLAMALKCYPLQPGGLLAIEAV I IGMTS 82
Cdd:COG3067 1 M S LGRAFA KNFLG Q SPDWYKL T I LA FLIINP IL FF TVG PFV A GWLLV A EFIFTLAMALKCYPLQPGGLLAIEAV L IGMTS 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 83 P QQ V G HE IAN NLEV V LLL I FMVAGIYFMKQLLLF A FTKLLL S I K SK RM L A LAFCLA S AFLSAFLDALTV I AV V ISV SL GF 162
Cdd:COG3067 81 P EH V Y HE VEA NLEV I LLL M FMVAGIYFMKQLLLF V FTKLLL G I R SK IL L S LAFCLA A AFLSAFLDALTV T AV I ISV AV GF 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 163 YS I Y NNFITDQN -- D VINAKH D N H I D t AKKKQT LEQFRAFLRSL M MHA G VGTALGGVMTMVGEPQNLIIA KNVN WDF VT F 240
Cdd:COG3067 161 YS V Y HKVASGKG fh D DHDHTD D D H V D - ELHRED LEQFRAFLRSL L MHA A VGTALGGVMTMVGEPQNLIIA EQAG WDF GE F 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 241 F I RMAP I T L PV F ICGLL V C F L V E H FK L FGYG TE LPE R VRQ V L E D Y D KKTS AKRT HKEK A Q LI A QA L I GI WLIV A LA F HLA 320
Cdd:COG3067 240 F L RMAP V T I PV L ICGLL T C V L L E K FK W FGYG AK LPE S VRQ I L A D F D REED AKRT KQDR A K LI V QA I I AV WLIV G LA L HLA 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 321 EVGLIGLSVIIL T T S F C G I T E EHA L GKAFEEALPFTALL T VFF SI VAVI V DQ Q LFTP F IQ F VL QVSETS QL SL FYL F NGL 400
Cdd:COG3067 320 EVGLIGLSVIIL A T A F N G V T D EHA I GKAFEEALPFTALL V VFF AV VAVI I DQ H LFTP I IQ W VL SLEGEQ QL AM FYL A NGL 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 401 LS SV SDNVFV G TVYINE ART A MQE G L I SHK QF EY LAVAINTGTNLPSVATPNGQAAFLFLLTS T L S PLIRLSYGRMV I MA 480
Cdd:COG3067 400 LS MI SDNVFV A TVYINE VKA A LDA G T I TRE QF DL LAVAINTGTNLPSVATPNGQAAFLFLLTS A L A PLIRLSYGRMV W MA 479
490
....*....|....*....
gi 499459322 481 LPYTIV M TLVGLL C VEFLL 499
Cdd:COG3067 480 LPYTIV L TLVGLL A VEFLL 498
NhaB
TIGR00774 Na+/H+ antiporter NhaB; These proteins are members of the NhaB Na+:H+ Antiporter (NhaB) Family ...
1-513
0e+00
Na+/H+ antiporter NhaB; These proteins are members of the NhaB Na+:H+ Antiporter (NhaB) Family (TC 2.A.34). The only characterised member of this family is the Escherichia coli NhaB protein, which has 12 GES predicted transmembrane regions, and catalyses sodium/proton exchange. Unlike NhaA this activity is not pH dependent. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129856
Cd Length: 515
Bit Score: 738.99
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 1 ME T S ILKTAV KNFLG N SPDWYKLAII I FLIINP LI FF F I N PFV T GWLLV I EFIFTLAMALKCYPLQPGGLLAIEA VI IGM 80
Cdd:TIGR00774 1 ME I S LGNAFI KNFLG K SPDWYKLAII A FLIINP IV FF L I S PFV A GWLLV A EFIFTLAMALKCYPLQPGGLLAIEA IA IGM 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 81 TS PQQ V G HE IAN N L EV V LLL I FMVAGIYFMKQLLLF A FTKLLL S I K SK RM L A LAFC L A S AFLSAFLDALTV I AVVISV SL 160
Cdd:TIGR00774 81 TS AAH V K HE LVA N I EV L LLL V FMVAGIYFMKQLLLF I FTKLLL G I R SK TL L S LAFC F A A AFLSAFLDALTV V AVVISV AV 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 161 GFY S IY NNFITDQN - DVINAKH D NH I DT a KKKQT LE Q FRAFLRSLMMHAGVGTALGGVMTMVGEPQNLIIA KNVN W D F VT 239
Cdd:TIGR00774 161 GFY G IY HKVASGNP i GDHDHTD D DT I TE - LTRDD LE N FRAFLRSLMMHAGVGTALGGVMTMVGEPQNLIIA DQAG W L F GE 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 240 FF I RM A P I TLPVFICGLL V C F LVE HF K L FGYG TE LP ER VRQ V L E D Y D KKTSAK RT HKE K AQ L IA QALI GI WLIVALA F HL 319
Cdd:TIGR00774 240 FF L RM S P V TLPVFICGLL T C A LVE KL K V FGYG EK LP DN VRQ I L V D F D REERKT RT NQD K IK L WV QALI AV WLIVALA L HL 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 320 A E VGLIGLSVIIL T TSF C G I T E EH AL GKAFEE A LPFTALL T VFFS I VAVI V DQ Q LF T P F I Q FVL QVS E TS QL S LFY L FNG 399
Cdd:TIGR00774 320 A A VGLIGLSVIIL A TSF T G V T D EH SI GKAFEE S LPFTALL A VFFS V VAVI I DQ E LF S P I I D FVL AAE E KT QL A LFY V FNG 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 400 LLSS V SDNVFVGTVYINEA RT A MQ EGLI SHK QFE Y LAVAINTGTNLPSVATPNGQAAFLFLLTS T L S PLIRLSYGRMV I M 479
Cdd:TIGR00774 400 LLSS I SDNVFVGTVYINEA KA A LT EGLI TRE QFE L LAVAINTGTNLPSVATPNGQAAFLFLLTS A L A PLIRLSYGRMV Y M 479
490 500 510
....*....|....*....|....*....|....
gi 499459322 480 ALPYTIV MTL VGLL CV EF L L I P V T DMMVHW G L I A 513
Cdd:TIGR00774 480 ALPYTIV LAI VGLL GI EF F L E P A T AWFYDA G W I L 513
NhaB
pfam06450 Bacterial Na+/H+ antiporter B (NhaB); This family consists of several bacterial Na+/H+ ...
1-513
0e+00
Bacterial Na+/H+ antiporter B (NhaB); This family consists of several bacterial Na+/H+ antiporter B (NhaB) proteins. The exact function of this family is unknown.
Pssm-ID: 283984
Cd Length: 515
Bit Score: 735.51
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 1 M ETSILKTAV KNFLG N SPDWYKLAII I FLIINP LI FF F I N PFV T GWLLV I EFIFTLAMALKCYPLQPGGLLAIEAV I IGM 80
Cdd:pfam06450 1 M PITNGQAFI KNFLG A SPDWYKLAII V FLIINP IV FF L I S PFV A GWLLV A EFIFTLAMALKCYPLQPGGLLAIEAV A IGM 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 81 TS PQQ V G HEI AN NLEV V LLL I FMVAGIYFMKQLLLF A FTKLLL S I K SK RM L A LAFC L A S AFLSAFLDALTV I AV V ISV SL 160
Cdd:pfam06450 81 TS AKH V K HEI MA NLEV L LLL V FMVAGIYFMKQLLLF I FTKLLL K I R SK IL L S LAFC F A A AFLSAFLDALTV V AV I ISV AV 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 161 GFY S IY NNFITDQ N DVINAK H -- D NH I DT a KKKQT LE Q FR A FLRSLMMHAGVGTALGGVMTMVGEPQNLIIA KNVN W D F V 238
Cdd:pfam06450 161 GFY G IY HKVASGN N LIDDHD H td D RK I IE - LQHEI LE K FR G FLRSLMMHAGVGTALGGVMTMVGEPQNLIIA EQAG W N F G 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 239 T FF I RM A P I T L PVFICGLL V CFLVE H F K LFGYG TE LP ER VR QV L E D Y D KKTSA KRT HKE K AQ LI A QA L IG I WLIV A LA F H 318
Cdd:pfam06450 240 E FF L RM S P V T V PVFICGLL T CFLVE K F R LFGYG EK LP DE VR KI L S D F D RTERE KRT NQD K IK LI V QA I IG V WLIV G LA L H 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 319 LA E VGLIGLSVIIL T TSF C G I T E EHA L GKAFEE A LPFTALL T VFFS I VAVI V DQQLF T P F IQFVL QVS E TS QL S LFY L FN 398
Cdd:pfam06450 320 LA A VGLIGLSVIIL A TSF T G V T D EHA I GKAFEE S LPFTALL A VFFS V VAVI I DQQLF S P I IQFVL SAE E NT QL A LFY I FN 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 399 GLLSS V SDNVFVGTVYINEA RT A MQE G L I SHK QFE Y LAVAINTGTNLPSVATPNGQAAFLFLLTS T L S PLIRLSYGRMV I 478
Cdd:pfam06450 400 GLLSS I SDNVFVGTVYINEA KA A LTN G V I TRH QFE L LAVAINTGTNLPSVATPNGQAAFLFLLTS A L A PLIRLSYGRMV W 479
490 500 510
....*....|....*....|....*....|....*
gi 499459322 479 MALPYTIV MTL VGLL CV EF L L I P V T DMMVHW G L I A 513
Cdd:pfam06450 480 MALPYTIV LSI VGLL AI EF I L E P A T IWFYDL G W I L 514
ArsB_NhaD_permease
cd00625 Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ...
70-493
3.69e-11
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain]
Cd Length: 396
Bit Score: 64.96
E-value: 3.69e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 70 L L A IEA V II G MT SP QQVGHE I ANNLEVV L LLIFMVAGIYFMKQ L LLFAFT KL LLSI K SK R M L A L AFC L AS A F LSAF L -- D 147
Cdd:cd00625 17 L G A VLL V LL G VV SP KEALSA I DWETILL L FGMMILSAALEETG L FDRLAA KL ARAS K GS R R L L L LLM L LT A A LSAF F sn D 96
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 148 A LT V IAVV I SVS L gfysiynnfitdqndvinakhdnhidtakkkq TLEQFRAFLRS L MMHAGVGTAL GG VM T MV G E P Q NL 227
Cdd:cd00625 97 A TA V LLTP I VLA L -------------------------------- LRKLGLSPPVP L LLALAFAANI GG AA T PI G N P P NL 144
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 228 IIA KNVNWD F VT F FIR MAP IT L PVFICG L LVCF L VEHF KL FGYGTELPERVRQV L EDYDKKTSAKRT hkekaq LIAQA L I 307
Cdd:cd00625 145 IIA SLSGLG F LD F LAF MAP PA L GLLLLL L GLLY L LFRK KL LLPDEDKLTVLAEP L PARPLLKKFLLL ------ ALLLL L L 218
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 308 GIW L IVA L AFHLAEVG L IG L SVII L TT sf C G ITE E HA L GKAFEEA L P F T A L L T V FFSIVAVIVDQQLFTPFIQFVLQVSE 387
Cdd:cd00625 219 FVL L FFF L IPLGLIAL L GA L LLLL L LV -- R G LDP E EV L KSVDWGT L L F F A G L F V LVGALESTGLLEWLAELLVALVGLPP 296
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 388 TSQ L S L FY L FNG LLS SVSD NV FVGTVYINE A RTA mqegli SHKQFEY LA V A I nt G TN L PSVA T PN G QA A F L FL L TSTLSP 467
Cdd:cd00625 297 LAA L L L IG L LSA LLS NFIS NV PTVALLLPI A ASL ------ APPEPAW LA L A L -- G ST L GGNL T LI G SL A N L IP L GAAENA 368
410 420
....*....|....*....|....*.
gi 499459322 468 LIRL S Y G RMVIMA LP Y T IVMTL V G LL 493
Cdd:cd00625 369 GVGI S F G EFLKVG LP L T LLSLV V S LL 394
ArsB
COG1055 Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
70-500
2.09e-10
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain]
Cd Length: 415
Bit Score: 62.45
E-value: 2.09e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 70 L L A IEAVII G MT S PQQVGHE I an NLEVV L L L IF M VAGIYFMKQLLL F AFTKLL L SIKS K --- R M L ALAFC L AS A F LSAFL 146
Cdd:COG1055 31 L G A ALLLLL G VV S LEDALEA I -- DWNTI L F L LG M MIIVAILDESGF F EWLAIK L ARRA K gsp R R L LWLLG L LT A L LSAFL 108
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 147 D AL T VIAVVIS V S L G fysiynnf I TDQNDV inakhdnhidtakkkqtle QFRA FL rslm MHAGVGTAL GG VM T MV G E P Q N 226
Cdd:COG1055 109 D ND T TALLLTP V V L A -------- I ARRLGL ------------------- NPVP FL ---- IAIVFAANI GG AA T PI G N P T N 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 227 LI IA KNVNWD F VT F FIRMA P IT L PVFICG LLV CF L V ehfklfg YGT ELP ERV rqvledy D KKTSA K RTH K EKAQ L IAQA L 306
Cdd:COG1055 158 IM IA SAGGLS F LD F LANLF P PS L VSLLVT LLV LY L L ------- FRK ELP AAP ------- D LEDDP K EAI K DRRL L RISL L 223
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 307 IGIW L I V ALAF H ------ L A EVG L I G LS V II L tts FCGITEEHA L G K A feeal PFTA LL TVF -- F SI V AVIVDQQ L FTPF 378
Cdd:COG1055 224 VLAL L L V GFVL H sflglp P A LIA L L G AA V LL L --- LARVDVREV L K K V ----- DWST LL FFI gl F VV V GGLENTG L LDLL 295
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 379 IQFVLQVSETSQ L SLFY L FN --- GL LS S V S DNV FVGTVYIN e ARTAMQEGLISHKQFEY LA VAINT G T NL psva TP N G Q A 455
Cdd:COG1055 296 AELLASLTGGNL L LAAL L IL wls AI LS A V V DNV PLVAALLP - LIPDLGATGNPEPLWLA LA LGATL G G NL ---- TP I G S A 370
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 499459322 456 A FLFL L TSTLSPL I RL S Y G RMVIMA LP Y T IVMT L VG LL CVEF L LI 500
Cdd:COG1055 371 A NVIV L GIAEKKG I KI S F G EFLKVG LP L T LLTL L IA LL YLLL L YF 415
CitMHS
pfam03600 Citrate transporter;
70-408
3.05e-07
Citrate transporter;
Pssm-ID: 460985 [Multi-domain]
Cd Length: 342
Bit Score: 52.31
E-value: 3.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 70 L L A IEA V II G MTS P QQVGHE I ANNLEVV LL LIFMVAG I YFMKQ L LLFAFT KLL - L SIKSK R M L AL A FC LA S A F LSAFL DA 148
Cdd:pfam03600 17 L G A VLL V LL G VLT P EEALSG I DSPTILL LL GMMIIGA I LERTG L FDRLAL KLL r L AGGKP R R L LV A LM LA T A L LSAFL SN 96
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 149 LTVIAVV I SVS L GFY siynnfitdqndvinakhdnhidtakkkqtl EQFRAFLRS L MMHAGVGTAL GG VM T MV G E P Q N L I 228
Cdd:pfam03600 97 DGTVLIM I PIV L ALA ------------------------------- RRLGLPPSP L LIALAFAANI GG TA T PI G D P P N I I 145
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 229 IA KNVNWD F VT F FIR M A P ITLPVFICGL L VCF L VEHF KL FGYGT E LPERVRQVLEDYD K KTSA krthkekaqliaq AL I G 308
Cdd:pfam03600 146 IA SALGLS F GD F GFF M F P PVGVALLLVG L LPL L LIFR KL LPVRK E EEAELEELRKRAI K DKLL ------------- LA I S 212
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 309 IWLIVALAFHLAEVGLIG L SVII L TTSFCGITE E H AL GKAFEEA L P F T A L L tvf F SI V AVIVDQQ L FTPFIQFVLQV S E - 387
Cdd:pfam03600 213 ALVLALVILGFLLLSVLA L AGAL L LLLTGVLDP E E AL KAVDWST L L F F A G L --- F IL V GALEKTG L ADALADALGGL S G l 289
330 340
....*....|....*....|.
gi 499459322 388 TSQ L S L FYLFNG LLS SVSD NV 408
Cdd:pfam03600 290 LVA L A L ILWLSA LLS AFIS NV 310
YbiR_permease
cd01117 Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to ...
70-493
8.97e-07
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate sodium, sulfate, arsenite and organic anions. A typical ArsB/NhaD permease is composed of 8-13 transmembrane domains.
Pssm-ID: 238537 [Multi-domain]
Cd Length: 384
Bit Score: 51.12
E-value: 8.97e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 70 L L A IEAVII G MT S PQQVGHE I an N L EVVL LL I - F MV AGIYFMKQLLLF A FT - KL L LSIK S K R M L ALAFC L A S AF LSA F L D 147
Cdd:cd01117 19 L G A ALMLLF G VI S LEDAPAA I -- D L DTII LL F g L MV VSAALELSGFFD A LG s RI L VKAG S P R R L LFLLV L L S GI LSA L L T 96
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 148 AL T VIA V VISVS L GF ysiynnfitdqndvinakhdnhidtak KKQTLEQFRAF L RS L mmha GVGTAL G GVM T MV G E PQNL 227
Cdd:cd01117 97 ND T ACL V FTPIV L EL --------------------------- ARVAGLPPIPL L LA L ---- ATAANI G SAA T PI G N PQNL 145
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 228 I IA KNVNWD F VT F FIR MAP IT L PVFICG L LVCFLVEHFK L F G YGTELPERVRQ V LE - DYDK K T sakrthkekaq L IAQA L 306
Cdd:cd01117 146 L IA SESGIS F PF F LAA MAP LA L LGLLLL L ILLLVLFPGE L K G LPLDKATKEEG V GA r KLAV K L ----------- L VLIL L 214
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 307 IGIWLIVA L AFHLAEVGLIGLS V II L T T SFCG ite EHA L G K AFEEA L P F T A L L TVFFSIV A VIVDQQLFTPFIQFVLQ V S 386
Cdd:cd01117 215 LLVAFLAL L GVIPLWTAALVAA V LL L L T RLKP --- RRV L K K VDWGL L L F F A G L FILVGGF A QGLPLEGLSRLLPLLDS V L 291
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 387 ETSQL S LF ylfngl LS SVSD NV FVGTVYINEART A MQEGLIS hkqfey LA VAINTGT NL psva T PN G Q AA F L FLLTSTLS 466
Cdd:cd01117 292 SLFLV S IG ------ LS QLIS NV PAVLLLLPFLPS A DEKDWLL ------ LA AGSTIAG NL ---- T LL G S AA N L IVAEAAER 355
410 420
....*....|....*....|....*..
gi 499459322 467 PLI RLS Y G RMVIMAL P Y T IVMTLV G L L 493
Cdd:cd01117 356 RGV RLS F G EFLKYGV P L T LLTAAI G I L 382
P_permease
cd01116 Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ...
70-333
1.61e-06
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain]
Cd Length: 413
Bit Score: 50.33
E-value: 1.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 70 L L A I EAVIIGMTSPQQVGHEI an NL E VVL LL IF M VAGIYFMKQLLL F AFTKLLLSIK SK --- RM L A L AFC L AS AFLSAFL 146
Cdd:cd01116 25 W L V I LGLATLSPDLETIVSWV -- DW E TLA LL LG M MIIVSILSETGV F EYLAIWAVKI SK grp WR L L L LLG L LT AFLSAFL 102
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 147 D AL T VIAVVIS V SL gfysiynn FITDQNDV inakhdnhidtakkkqtle QFRAF L R S LMMH A GV G talg G VM T MV G E P Q N 226
Cdd:cd01116 103 D NV T TVLLMVP V TI -------- RLCEVLGL ------------------- NPVPV L I S EVIA A NI G ---- G AA T LI G D P P N 151
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 227 LI I AKNVNWD F VT F FIR M A P ITLPVFICGLLVCFL vehfk L FGYGTELP E RVRQV L EDYDK K TSA K R thkek AQ L IAQA L 306
Cdd:cd01116 152 IM I GSAAGLT F ND F LLH M L P SVVLALVVTFILLYF ----- L YRNILKAR E EDVLA L AELEP K YPI K D ----- KV L LLKS L 221
250 260
....*....|....*....|....*..
gi 499459322 307 I g I WLI V ALA F H L AEVGLIG L SV I I L T 333
Cdd:cd01116 222 T - I LTL V IIG F V L HSPLGVS L GW I A L L 247
CitT
COG0471 Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
126-333
3.10e-05
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain]
Cd Length: 369
Bit Score: 46.30
E-value: 3.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 126 K S KRM L A L AFC LA S A F LSAF LDALTVI A VVISVS L GFYSIYN nfitdqndvinakhdnhidtakkkqt L E QFRA F LRS L M 205
Cdd:COG0471 29 G S PLR L L L GLM LA T A L LSAF ISNTARA A MMLPIA L SIAAALG -------------------------- S E KRSK F GSA L L 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459322 206 MHAGVGTAL GG VM T MV G E P Q NLI I A K ------ NVNWD F VTFF irma PIT LPV FIC GLL VCF LV EHFK L FGYGT E L P ERVR 279
Cdd:COG0471 83 LPIAFAASI GG MG T LI G T P P NLI A A G lleeat GIPIS F FEWM ---- LVG LPV ALV GLL LLW LV LYRL L PPEIK E V P GSKE 158
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 499459322 280 QVL E DYDKKTSAK R TH K e K A QL I AQALIGI W LI - VALAFHL A E V G L I G LSVII LT 333
Cdd:COG0471 159 VIR E ELAELGPLS R RE K - I A LA I FALTVLL W IT g SLHGIPI A V V A L L G AVLLL LT 212
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
