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Conserved domains on  [gi|499459075|ref|WP_011146539|]
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MULTISPECIES: type VI secretion lipoprotein TssJ [Photorhabdus]

Protein Classification

type VI secretion lipoprotein TssJ( domain architecture ID 10007514)

type VI secretion lipoprotein TssJ is an outer membrane-associated component that forms the core complex with TssL and TssM inner-membrane proteins

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG3521 COG3521
Predicted component of the type VI protein secretion system [Intracellular trafficking, ...
 1-188 3.44e-23

Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 442743  Cd Length: 168  Bit Score: 91.57  E-value: 3.44e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459075   1 MNNINfySIIKRRFLILTVILLISGCShsiSNDEKRLQAIEQAKPVyasnaiRLKITAVPQLNVF-NNIPNSCTILIVQA 79
Cdd:COG3521    1 MKKRL--KRLARLLLLLLLLLLLAGCG---STQKVTVIFYKQPTTL------HLTLTAAPDLNPDaNGRPSPVVVRVYQL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459075  80 EKREQLDKllanpALLRNLFSGTGAT--EHILQLDNYVMMPGQSVSLHIDRAEQARYIALIAGYYPAPESTHTRVLSLPl 157
Cdd:COG3521   70 KDDSAFES-----ADFFALLDDDEEAlgADLLSVKELTLLPGESKTLDLPLDPEARYIGVVALFRDPDGARWRLVIPVP- 143

                        170       180       190
                 ....*....|....*....|....*....|.
gi 499459075 158 RLEQHGwwnsawsaefvpmRINLTLGRYAIT 188
Cdd:COG3521  144 ELDSDG-------------KLTIELGGNAIT 161
 
Name Accession Description Interval E-value
COG3521 COG3521
Predicted component of the type VI protein secretion system [Intracellular trafficking, ...
 1-188 3.44e-23

Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442743  Cd Length: 168  Bit Score: 91.57  E-value: 3.44e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459075   1 MNNINfySIIKRRFLILTVILLISGCShsiSNDEKRLQAIEQAKPVyasnaiRLKITAVPQLNVF-NNIPNSCTILIVQA 79
Cdd:COG3521    1 MKKRL--KRLARLLLLLLLLLLLAGCG---STQKVTVIFYKQPTTL------HLTLTAAPDLNPDaNGRPSPVVVRVYQL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459075  80 EKREQLDKllanpALLRNLFSGTGAT--EHILQLDNYVMMPGQSVSLHIDRAEQARYIALIAGYYPAPESTHTRVLSLPl 157
Cdd:COG3521   70 KDDSAFES-----ADFFALLDDDEEAlgADLLSVKELTLLPGESKTLDLPLDPEARYIGVVALFRDPDGARWRLVIPVP- 143

                        170       180       190
                 ....*....|....*....|....*....|.
gi 499459075 158 RLEQHGwwnsawsaefvpmRINLTLGRYAIT 188
Cdd:COG3521  144 ELDSDG-------------KLTIELGGNAIT 161
T6SS-SciN pfam12790
Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113; One of the virulence mechanisms of ...
 52-156 6.21e-08

Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113; One of the virulence mechanisms of E coli is the production of toxins which it produces from dedicated machineries called secretion systems. Seven secretion systems have been described, which assemble from 3 to up to more than 20 subunits. These secretion systems derive from or have co-evolved with bacterial organelles such as ABC transporters (type I), type IV pili (type 2), flagella (type 3), or conjugative machines (type IV). The type VI secretion system (T6SS) is present in most pathogens that have contact with animals, plants, or humans. SciN is a lipoprotein tethered to the outer membrane and expressed in the periplasm of E coli and is essential for T6S-dependent secretion of the Hcp-like SciD protein and for biofilm formation.


Pssm-ID: 432786  Cd Length: 120  Bit Score: 49.51  E-value: 6.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459075   52 IRLKITAVPQLNVFNN-IPNSCTILIVQAEKREQLDKLlANPALLRNLFSGTGATehILQLDNYVMMPGQSVSLHIDRAE 130
Cdd:pfam12790   3 LDLTLVAAADLNPDENgRPSPVVVRVYQLKDDSAFNAA-DFFSLYDDDKAALGAD--LVAVDEFILRPGETRTLSLPLDP 79

                          90       100
                  ....*....|....*....|....*.
gi 499459075  131 QARYIALIAGYYPAPESTHTRVLSLP 156
Cdd:pfam12790  80 GARYVGVVAAYRDLDNARWRLVIPIP 105
 
Name Accession Description Interval E-value
COG3521 COG3521
Predicted component of the type VI protein secretion system [Intracellular trafficking, ...
 1-188 3.44e-23

Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442743  Cd Length: 168  Bit Score: 91.57  E-value: 3.44e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459075   1 MNNINfySIIKRRFLILTVILLISGCShsiSNDEKRLQAIEQAKPVyasnaiRLKITAVPQLNVF-NNIPNSCTILIVQA 79
Cdd:COG3521    1 MKKRL--KRLARLLLLLLLLLLLAGCG---STQKVTVIFYKQPTTL------HLTLTAAPDLNPDaNGRPSPVVVRVYQL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459075  80 EKREQLDKllanpALLRNLFSGTGAT--EHILQLDNYVMMPGQSVSLHIDRAEQARYIALIAGYYPAPESTHTRVLSLPl 157
Cdd:COG3521   70 KDDSAFES-----ADFFALLDDDEEAlgADLLSVKELTLLPGESKTLDLPLDPEARYIGVVALFRDPDGARWRLVIPVP- 143

                        170       180       190
                 ....*....|....*....|....*....|.
gi 499459075 158 RLEQHGwwnsawsaefvpmRINLTLGRYAIT 188
Cdd:COG3521  144 ELDSDG-------------KLTIELGGNAIT 161
T6SS-SciN pfam12790
Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113; One of the virulence mechanisms of ...
 52-156 6.21e-08

Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113; One of the virulence mechanisms of E coli is the production of toxins which it produces from dedicated machineries called secretion systems. Seven secretion systems have been described, which assemble from 3 to up to more than 20 subunits. These secretion systems derive from or have co-evolved with bacterial organelles such as ABC transporters (type I), type IV pili (type 2), flagella (type 3), or conjugative machines (type IV). The type VI secretion system (T6SS) is present in most pathogens that have contact with animals, plants, or humans. SciN is a lipoprotein tethered to the outer membrane and expressed in the periplasm of E coli and is essential for T6S-dependent secretion of the Hcp-like SciD protein and for biofilm formation.


Pssm-ID: 432786  Cd Length: 120  Bit Score: 49.51  E-value: 6.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499459075   52 IRLKITAVPQLNVFNN-IPNSCTILIVQAEKREQLDKLlANPALLRNLFSGTGATehILQLDNYVMMPGQSVSLHIDRAE 130
Cdd:pfam12790   3 LDLTLVAAADLNPDENgRPSPVVVRVYQLKDDSAFNAA-DFFSLYDDDKAALGAD--LVAVDEFILRPGETRTLSLPLDP 79

                          90       100
                  ....*....|....*....|....*.
gi 499459075  131 QARYIALIAGYYPAPESTHTRVLSLP 156
Cdd:pfam12790  80 GARYVGVVAAYRDLDNARWRLVIPIP 105
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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