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Conserved domains on  [gi|499412773|ref|WP_011100240|]
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electron transfer flavoprotein subunit beta/FixA family protein [Clostridium tetani]

Protein Classification

electron transfer flavoprotein subunit beta/FixA family protein( domain architecture ID 10005277)

electron transfer flavoprotein (ETF) subunit beta/FixA family protein similar to the beta subunit of ETF, which transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase, and protein FixA, which plays a role in a redox process involved in nitrogen fixation

CATH:  3.40.50.620
EC:  1.-.-.-
Gene Ontology:  GO:0009055
SCOP:  4003848

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
flavo_sub_EftB super family cl46210
electron transfer flavoprotein subunit beta; Members of this family electron transfer ...
2-262 9.17e-139

electron transfer flavoprotein subunit beta; Members of this family electron transfer flavoprotein subunit beta (EftB) as found in pathways for leucine reduction to isocaproate as seen in the strict anaerobe Clostridium difficile.


The actual alignment was detected with superfamily member NF040731:

Pssm-ID: 468695  Cd Length: 260  Bit Score: 390.61  E-value: 9.17e-139
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773   2 NIVVCIKQVPDTTEVRIDPIKGTLIRDGIPSIINPDDKNAIEEALKIKDKIKGTKVIAITMGPLQSESALREALAMGVDK 81
Cdd:NF040731   1 KILVCVKQVPDTNEVKIDPVTGTLIRDGVPSILNPDDANALEEALKIKDEYEDVTVTVITMGPPQADDMLRECLAMGADE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773  82 GILLSDRKFAGSDTLATSYILSSVIKKIGDYDIIFCGRQAIDGDTAQVGPGIAEHLKIPQITYVSGLDVNGRELIVNRDI 161
Cdd:NF040731  81 AYLLSDRAFGGADTWATSNTIAAAIRKIGDYDIIFAGRQAIDGDTAQVGPQIAEKLGIPQVTYVQDFKIEDDKVIVQRQL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773 162 EEGSYVIKSKMPILLTAIKELNEPRYPSIAGIYKAHrEKRIDIWTANDLEIDEEKIGLNGSPTKVKKSFTPSISSQGEII 241
Cdd:NF040731 161 EDGYEVIEVQTPCLLTAVKELNKPRYMSVKGIFDAY-EKEITVWNIDDVDVSPEEVGLKASPTRVFRSFTPPPKGKGVML 239
                        250       260
                 ....*....|....*....|.
gi 499412773 242 EGTAEEASYKLVSKLREKQII 262
Cdd:NF040731 240 EGTVKEMAAKLISRLKKKHII 260
 
Name Accession Description Interval E-value
flavo_sub_EftB NF040731
electron transfer flavoprotein subunit beta; Members of this family electron transfer ...
2-262 9.17e-139

electron transfer flavoprotein subunit beta; Members of this family electron transfer flavoprotein subunit beta (EftB) as found in pathways for leucine reduction to isocaproate as seen in the strict anaerobe Clostridium difficile.


Pssm-ID: 468695  Cd Length: 260  Bit Score: 390.61  E-value: 9.17e-139
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773   2 NIVVCIKQVPDTTEVRIDPIKGTLIRDGIPSIINPDDKNAIEEALKIKDKIKGTKVIAITMGPLQSESALREALAMGVDK 81
Cdd:NF040731   1 KILVCVKQVPDTNEVKIDPVTGTLIRDGVPSILNPDDANALEEALKIKDEYEDVTVTVITMGPPQADDMLRECLAMGADE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773  82 GILLSDRKFAGSDTLATSYILSSVIKKIGDYDIIFCGRQAIDGDTAQVGPGIAEHLKIPQITYVSGLDVNGRELIVNRDI 161
Cdd:NF040731  81 AYLLSDRAFGGADTWATSNTIAAAIRKIGDYDIIFAGRQAIDGDTAQVGPQIAEKLGIPQVTYVQDFKIEDDKVIVQRQL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773 162 EEGSYVIKSKMPILLTAIKELNEPRYPSIAGIYKAHrEKRIDIWTANDLEIDEEKIGLNGSPTKVKKSFTPSISSQGEII 241
Cdd:NF040731 161 EDGYEVIEVQTPCLLTAVKELNKPRYMSVKGIFDAY-EKEITVWNIDDVDVSPEEVGLKASPTRVFRSFTPPPKGKGVML 239
                        250       260
                 ....*....|....*....|.
gi 499412773 242 EGTAEEASYKLVSKLREKQII 262
Cdd:NF040731 240 EGTVKEMAAKLISRLKKKHII 260
FixA COG2086
Electron transfer flavoprotein, alpha and beta subunits [Energy production and conversion];
1-262 1.16e-136

Electron transfer flavoprotein, alpha and beta subunits [Energy production and conversion];


Pssm-ID: 441689  Cd Length: 261  Bit Score: 385.23  E-value: 1.16e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773   1 MNIVVCIKQVPDTT-EVRIDPIKGTLIRDGIPSIINPDDKNAIEEALKIKDKiKGTKVIAITMGPLQSESALREALAMGV 79
Cdd:COG2086    1 MKILVCVKQVPDTNvKIRVDPDGGTLDREGVPSIINPYDEYALEEALRLKEK-GGGEVTVVSMGPPQAEEALRKALAMGA 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773  80 DKGILLSDRKFAGSDTLATSYILSSVIKKIGDYDIIFCGRQAIDGDTAQVGPGIAEHLKIPQITYVSGLDVNGRELIVNR 159
Cdd:COG2086   80 DRAILVSDDAFAGADTLATAKALAAAIKKIGGPDLVLCGKQAIDGDTGQVGPMLAELLGLPQVTYVSKLEVEGGTVTVER 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773 160 DIEEGSYVIKSKMPILLTAIKELNEPRYPSIAGIYKAhREKRIDIWTANDLEIDEEKIGLNGSPTKVKKSFTPSISSQGE 239
Cdd:COG2086  160 ELEGGLETVEVPLPAVVTVDKGLNEPRYPSLKGIMKA-KKKPIEVLSAADLGLDPAKVGLKGSPTKVVKVFAPPARRAGE 238
                        250       260
                 ....*....|....*....|...
gi 499412773 240 IIEGTAEEASYKLVSKLREKQII 262
Cdd:COG2086  239 IIEGDPEEAAAELVEKLKEEAKV 261
ETF_beta cd01714
electron transfer flavoprotein (ETF) beta; The electron transfer flavoprotein (ETF) serves as ...
1-213 1.70e-112

electron transfer flavoprotein (ETF) beta; The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is a heterodimer, consisting of an alpha and a beta subunit, which binds one molecule of FAD per dimer. A similar system also exists in some bacteria. The homologous pair of proteins (FixA/FixB) are essential for nitrogen fixation. The beta subunit is distantly related to and forms a heterodimer with the alpha subunit.


Pssm-ID: 467487  Cd Length: 210  Bit Score: 322.18  E-value: 1.70e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773   1 MNIVVCIKQVPDTTEVRIDPIKGTLIRDGIPSIINPDDKNAIEEALKIKDKiKGTKVIAITMGPLQSESALREALAMGVD 80
Cdd:cd01714    1 MKILVCVKQVPDTEEKKRDPKTGTLDREGVPSIINPFDENAVEEALRLKEK-HGGEVTAVSMGPPQAEEALREALAMGAD 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773  81 KGILLSDRKFAGSDTLATSYILSSVIKKIGdYDIIFCGRQAIDGDTAQVGPGIAEHLKIPQITYVSGLDVNGRELIVNRD 160
Cdd:cd01714   80 RAILVSDRAFAGADTLATAKALAAAIKKEG-PDLILAGKQAIDGDTAQVGPQLAELLGWPQVTYVSKIEIEGGKVTVERE 158
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 499412773 161 IEEGSYVIKSKMPILLTAIKELNEPRYPSIAGIYKAHReKRIDIWTANDLEID 213
Cdd:cd01714  159 LEGGLETVEVPLPAVITVDLRLNEPRYPSLPGIMKAKK-KPIEVWTAADLGVD 210
ETF smart00893
Electron transfer flavoprotein domain; Electron transfer flavoproteins (ETFs) serve as ...
26-213 5.66e-51

Electron transfer flavoprotein domain; Electron transfer flavoproteins (ETFs) serve as specific electron acceptors for primary dehydrogenases, transferring the electrons to terminal respiratory systems. They can be functionally classified into constitutive, "housekeeping" ETFs, mainly involved in the oxidation of fatty acids (Group I), and ETFs produced by some prokaryotes under specific growth conditions, receiving electrons only from the oxidation of specific substrates (Group II). ETFs are heterodimeric proteins composed of an alpha and beta subunit, and contain an FAD cofactor and AMP. ETF consists of three domains: domains I and II are formed by the N- and C-terminal portions of the alpha subunit, respectively, while domain III is formed by the beta subunit. Domains I and III share an almost identical alpha-beta-alpha sandwich fold, while domain II forms an alpha-beta-alpha sandwich similar to that of bacterial flavodoxins. FAD is bound in a cleft between domains II and III, while domain III binds the AMP molecule. Interactions between domains I and III stabilise the protein, forming a shallow bowl where domain II resides. This entry represents the N-terminal domain of both the alpha and beta subunits from Group I and Group II ETFs.


Pssm-ID: 214890 [Multi-domain]  Cd Length: 185  Bit Score: 164.75  E-value: 5.66e-51
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773    26 IRDGIPSIINPDDKNAIEEALKIKDKIKgtkVIAITMGPLQSESALREALAMGVDKGILLSDRKFAGSDTLATSYILSSV 105
Cdd:smart00893   1 AEHGVGALINPVDLEALEAARRLKEKGE---VTAVVVGPPAAEEALREALAMGADKVYLVDDDALAGYDTLATLAEALAA 77
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773   106 IKKIGDYDIIFCGRQaidGDTAQVGPGIAEHLKIPQITYVSGLDVNGrELIVNRDIEEGSY---VIKSKMPILLTAIKEL 182
Cdd:smart00893  78 LIKEEKPDLVLAGAT---SDGKQLAPRLAALLGVPQITDVTKLEVDG-DTFVRRIYGGGAIateVVEADLPAVITVRPGA 153
                          170       180       190
                   ....*....|....*....|....*....|....*
gi 499412773   183 NEP----RYPSIAGIYKAhreKRIDIWTANDLEID 213
Cdd:smart00893 154 FEPaprdGYPSLVEIMKA---KKKPILSLADLGVD 185
ETF pfam01012
Electron transfer flavoprotein domain; This family includes the homologous domain shared ...
23-186 1.83e-43

Electron transfer flavoprotein domain; This family includes the homologous domain shared between the alpha and beta subunits of the electron transfer flavoprotein.


Pssm-ID: 425985 [Multi-domain]  Cd Length: 178  Bit Score: 145.45  E-value: 1.83e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773   23 GTLIRDGiPSIINPDDKNAIEEALKIKDKiKGTKVIAITMGPLQSESALREALA-MGVDKGILLSDRKFAGSDTLATSYI 101
Cdd:pfam01012   2 LVVAEHG-NGKLNPVDLEALEAARRLAEK-GGGEVTAVVLGPPAAEEALAEALAaMGADKVLVVDDPALAGYDAEAYAAA 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773  102 LSSVIKKIGdYDIIFCGRQAIDGdtaQVGPGIAEHLKIPQITYVSGLDVNGReLIVNRDIEEG---SYVIKSKMPILLTA 178
Cdd:pfam01012  80 LAALIKKEG-PDLVLAGATSIGK---DLAPRVAALLGTPLVTDVTKLEVEGG-LTATRPIYGGnglATVVEPSLPAVLTV 154

                  ....*...
gi 499412773  179 IKELNEPR 186
Cdd:pfam01012 155 RPGAFEPA 162
PRK12342 PRK12342
electron transfer flavoprotein;
1-258 2.01e-28

electron transfer flavoprotein;


Pssm-ID: 183455  Cd Length: 254  Bit Score: 108.66  E-value: 2.01e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773   1 MNIVVCIKQVPDTTEVRIDPIKgTLIRDGIPSIINPDDKNAIEEALKIKDKikGTKVIAITMG--PLQSESALREALAMG 78
Cdd:PRK12342   1 MKIITCFKLVPEEQDIVVTPER-TLNFDNAEAKISQFDLNAIEAASQLATD--GDEIAALTVGgsLLQNSKVRKDVLSRG 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773  79 VDKGILLSDRKFAGSDTLATSYILSSVIKKIGdYDIIFCGRQAIDGDTAQVGPGIAEHLKIPQITYVSGLDVNGRELIVN 158
Cdd:PRK12342  78 PHSLYLVQDAQLEHALPLDTAKALAAAIEKIG-FDLLLFGEGSGDLYAQQVGLLLGELLQLPVINAVSKIQRQGNKLIVE 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773 159 RDIEEGSYVIKSKMPILLTAIKELNEPRYPSIAGIYKAHReKRIDIWTANDLEIDEEKIglngsPTKVKKSFTPSISSQG 238
Cdd:PRK12342 157 RTLEDDVEVLELSLPAVLCVTSDINVPRIPSMKAILGAGK-KPVTQWQASDIGWSQSAP-----LAELVGIRVPPQTERK 230
                        250       260
                 ....*....|....*....|.
gi 499412773 239 EII-EGTAEEASYKLVSKLRE 258
Cdd:PRK12342 231 HIIlDNDSPEAIAELAEHLKK 251
 
Name Accession Description Interval E-value
flavo_sub_EftB NF040731
electron transfer flavoprotein subunit beta; Members of this family electron transfer ...
2-262 9.17e-139

electron transfer flavoprotein subunit beta; Members of this family electron transfer flavoprotein subunit beta (EftB) as found in pathways for leucine reduction to isocaproate as seen in the strict anaerobe Clostridium difficile.


Pssm-ID: 468695  Cd Length: 260  Bit Score: 390.61  E-value: 9.17e-139
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773   2 NIVVCIKQVPDTTEVRIDPIKGTLIRDGIPSIINPDDKNAIEEALKIKDKIKGTKVIAITMGPLQSESALREALAMGVDK 81
Cdd:NF040731   1 KILVCVKQVPDTNEVKIDPVTGTLIRDGVPSILNPDDANALEEALKIKDEYEDVTVTVITMGPPQADDMLRECLAMGADE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773  82 GILLSDRKFAGSDTLATSYILSSVIKKIGDYDIIFCGRQAIDGDTAQVGPGIAEHLKIPQITYVSGLDVNGRELIVNRDI 161
Cdd:NF040731  81 AYLLSDRAFGGADTWATSNTIAAAIRKIGDYDIIFAGRQAIDGDTAQVGPQIAEKLGIPQVTYVQDFKIEDDKVIVQRQL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773 162 EEGSYVIKSKMPILLTAIKELNEPRYPSIAGIYKAHrEKRIDIWTANDLEIDEEKIGLNGSPTKVKKSFTPSISSQGEII 241
Cdd:NF040731 161 EDGYEVIEVQTPCLLTAVKELNKPRYMSVKGIFDAY-EKEITVWNIDDVDVSPEEVGLKASPTRVFRSFTPPPKGKGVML 239
                        250       260
                 ....*....|....*....|.
gi 499412773 242 EGTAEEASYKLVSKLREKQII 262
Cdd:NF040731 240 EGTVKEMAAKLISRLKKKHII 260
FixA COG2086
Electron transfer flavoprotein, alpha and beta subunits [Energy production and conversion];
1-262 1.16e-136

Electron transfer flavoprotein, alpha and beta subunits [Energy production and conversion];


Pssm-ID: 441689  Cd Length: 261  Bit Score: 385.23  E-value: 1.16e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773   1 MNIVVCIKQVPDTT-EVRIDPIKGTLIRDGIPSIINPDDKNAIEEALKIKDKiKGTKVIAITMGPLQSESALREALAMGV 79
Cdd:COG2086    1 MKILVCVKQVPDTNvKIRVDPDGGTLDREGVPSIINPYDEYALEEALRLKEK-GGGEVTVVSMGPPQAEEALRKALAMGA 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773  80 DKGILLSDRKFAGSDTLATSYILSSVIKKIGDYDIIFCGRQAIDGDTAQVGPGIAEHLKIPQITYVSGLDVNGRELIVNR 159
Cdd:COG2086   80 DRAILVSDDAFAGADTLATAKALAAAIKKIGGPDLVLCGKQAIDGDTGQVGPMLAELLGLPQVTYVSKLEVEGGTVTVER 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773 160 DIEEGSYVIKSKMPILLTAIKELNEPRYPSIAGIYKAhREKRIDIWTANDLEIDEEKIGLNGSPTKVKKSFTPSISSQGE 239
Cdd:COG2086  160 ELEGGLETVEVPLPAVVTVDKGLNEPRYPSLKGIMKA-KKKPIEVLSAADLGLDPAKVGLKGSPTKVVKVFAPPARRAGE 238
                        250       260
                 ....*....|....*....|...
gi 499412773 240 IIEGTAEEASYKLVSKLREKQII 262
Cdd:COG2086  239 IIEGDPEEAAAELVEKLKEEAKV 261
ETF_beta cd01714
electron transfer flavoprotein (ETF) beta; The electron transfer flavoprotein (ETF) serves as ...
1-213 1.70e-112

electron transfer flavoprotein (ETF) beta; The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is a heterodimer, consisting of an alpha and a beta subunit, which binds one molecule of FAD per dimer. A similar system also exists in some bacteria. The homologous pair of proteins (FixA/FixB) are essential for nitrogen fixation. The beta subunit is distantly related to and forms a heterodimer with the alpha subunit.


Pssm-ID: 467487  Cd Length: 210  Bit Score: 322.18  E-value: 1.70e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773   1 MNIVVCIKQVPDTTEVRIDPIKGTLIRDGIPSIINPDDKNAIEEALKIKDKiKGTKVIAITMGPLQSESALREALAMGVD 80
Cdd:cd01714    1 MKILVCVKQVPDTEEKKRDPKTGTLDREGVPSIINPFDENAVEEALRLKEK-HGGEVTAVSMGPPQAEEALREALAMGAD 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773  81 KGILLSDRKFAGSDTLATSYILSSVIKKIGdYDIIFCGRQAIDGDTAQVGPGIAEHLKIPQITYVSGLDVNGRELIVNRD 160
Cdd:cd01714   80 RAILVSDRAFAGADTLATAKALAAAIKKEG-PDLILAGKQAIDGDTAQVGPQLAELLGWPQVTYVSKIEIEGGKVTVERE 158
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 499412773 161 IEEGSYVIKSKMPILLTAIKELNEPRYPSIAGIYKAHReKRIDIWTANDLEID 213
Cdd:cd01714  159 LEGGLETVEVPLPAVITVDLRLNEPRYPSLPGIMKAKK-KPIEVWTAADLGVD 210
ETF smart00893
Electron transfer flavoprotein domain; Electron transfer flavoproteins (ETFs) serve as ...
26-213 5.66e-51

Electron transfer flavoprotein domain; Electron transfer flavoproteins (ETFs) serve as specific electron acceptors for primary dehydrogenases, transferring the electrons to terminal respiratory systems. They can be functionally classified into constitutive, "housekeeping" ETFs, mainly involved in the oxidation of fatty acids (Group I), and ETFs produced by some prokaryotes under specific growth conditions, receiving electrons only from the oxidation of specific substrates (Group II). ETFs are heterodimeric proteins composed of an alpha and beta subunit, and contain an FAD cofactor and AMP. ETF consists of three domains: domains I and II are formed by the N- and C-terminal portions of the alpha subunit, respectively, while domain III is formed by the beta subunit. Domains I and III share an almost identical alpha-beta-alpha sandwich fold, while domain II forms an alpha-beta-alpha sandwich similar to that of bacterial flavodoxins. FAD is bound in a cleft between domains II and III, while domain III binds the AMP molecule. Interactions between domains I and III stabilise the protein, forming a shallow bowl where domain II resides. This entry represents the N-terminal domain of both the alpha and beta subunits from Group I and Group II ETFs.


Pssm-ID: 214890 [Multi-domain]  Cd Length: 185  Bit Score: 164.75  E-value: 5.66e-51
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773    26 IRDGIPSIINPDDKNAIEEALKIKDKIKgtkVIAITMGPLQSESALREALAMGVDKGILLSDRKFAGSDTLATSYILSSV 105
Cdd:smart00893   1 AEHGVGALINPVDLEALEAARRLKEKGE---VTAVVVGPPAAEEALREALAMGADKVYLVDDDALAGYDTLATLAEALAA 77
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773   106 IKKIGDYDIIFCGRQaidGDTAQVGPGIAEHLKIPQITYVSGLDVNGrELIVNRDIEEGSY---VIKSKMPILLTAIKEL 182
Cdd:smart00893  78 LIKEEKPDLVLAGAT---SDGKQLAPRLAALLGVPQITDVTKLEVDG-DTFVRRIYGGGAIateVVEADLPAVITVRPGA 153
                          170       180       190
                   ....*....|....*....|....*....|....*
gi 499412773   183 NEP----RYPSIAGIYKAhreKRIDIWTANDLEID 213
Cdd:smart00893 154 FEPaprdGYPSLVEIMKA---KKKPILSLADLGVD 185
ETF pfam01012
Electron transfer flavoprotein domain; This family includes the homologous domain shared ...
23-186 1.83e-43

Electron transfer flavoprotein domain; This family includes the homologous domain shared between the alpha and beta subunits of the electron transfer flavoprotein.


Pssm-ID: 425985 [Multi-domain]  Cd Length: 178  Bit Score: 145.45  E-value: 1.83e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773   23 GTLIRDGiPSIINPDDKNAIEEALKIKDKiKGTKVIAITMGPLQSESALREALA-MGVDKGILLSDRKFAGSDTLATSYI 101
Cdd:pfam01012   2 LVVAEHG-NGKLNPVDLEALEAARRLAEK-GGGEVTAVVLGPPAAEEALAEALAaMGADKVLVVDDPALAGYDAEAYAAA 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773  102 LSSVIKKIGdYDIIFCGRQAIDGdtaQVGPGIAEHLKIPQITYVSGLDVNGReLIVNRDIEEG---SYVIKSKMPILLTA 178
Cdd:pfam01012  80 LAALIKKEG-PDLVLAGATSIGK---DLAPRVAALLGTPLVTDVTKLEVEGG-LTATRPIYGGnglATVVEPSLPAVLTV 154

                  ....*...
gi 499412773  179 IKELNEPR 186
Cdd:pfam01012 155 RPGAFEPA 162
PRK12342 PRK12342
electron transfer flavoprotein;
1-258 2.01e-28

electron transfer flavoprotein;


Pssm-ID: 183455  Cd Length: 254  Bit Score: 108.66  E-value: 2.01e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773   1 MNIVVCIKQVPDTTEVRIDPIKgTLIRDGIPSIINPDDKNAIEEALKIKDKikGTKVIAITMG--PLQSESALREALAMG 78
Cdd:PRK12342   1 MKIITCFKLVPEEQDIVVTPER-TLNFDNAEAKISQFDLNAIEAASQLATD--GDEIAALTVGgsLLQNSKVRKDVLSRG 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773  79 VDKGILLSDRKFAGSDTLATSYILSSVIKKIGdYDIIFCGRQAIDGDTAQVGPGIAEHLKIPQITYVSGLDVNGRELIVN 158
Cdd:PRK12342  78 PHSLYLVQDAQLEHALPLDTAKALAAAIEKIG-FDLLLFGEGSGDLYAQQVGLLLGELLQLPVINAVSKIQRQGNKLIVE 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773 159 RDIEEGSYVIKSKMPILLTAIKELNEPRYPSIAGIYKAHReKRIDIWTANDLEIDEEKIglngsPTKVKKSFTPSISSQG 238
Cdd:PRK12342 157 RTLEDDVEVLELSLPAVLCVTSDINVPRIPSMKAILGAGK-KPVTQWQASDIGWSQSAP-----LAELVGIRVPPQTERK 230
                        250       260
                 ....*....|....*....|.
gi 499412773 239 EII-EGTAEEASYKLVSKLRE 258
Cdd:PRK12342 231 HIIlDNDSPEAIAELAEHLKK 251
PRK03359 PRK03359
putative electron transfer flavoprotein FixA; Reviewed
1-258 8.09e-23

putative electron transfer flavoprotein FixA; Reviewed


Pssm-ID: 179569  Cd Length: 256  Bit Score: 93.69  E-value: 8.09e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773   1 MNIVVCIKQVPDTTEVRIDPIKGTLIRDGIPSIINPDDKNAIEEALKIKDKIKGTKVIAITMG--PLQSESALREALAMG 78
Cdd:PRK03359   1 MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTALSVGgkALTNAKGRKDVLSRG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773  79 VDKGILLSDRKFAGSDTLATSYILSSVIKKIGdYDIIFCGRQAIDGDTAQVGPGIAEHLKIPQITYVSG-LDVNGRELIV 157
Cdd:PRK03359  81 PDELIVVIDDQFEQALPQQTASALAAAAQKAG-FDLILCGDGSSDLYAQQVGLLVGEILNIPAINGVSKiISLTDDTLTV 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499412773 158 NRDIEEGSYVIKSKMPILLTAIKELNEPRYPSIAGIYKAHReKRIDIWTANDLEIDEEKIGLNGSPTKVKKSftpsiSSQ 237
Cdd:PRK03359 160 ERELEDEVETLSIPLPAVIAVSTDINSPQIPSMKAILGAAK-KPVQVWSAADIGFNAEPAWSEQQVAAPKQR-----ERQ 233
                        250       260
                 ....*....|....*....|.
gi 499412773 238 GEIIEGTAEEASYKLVSKLRE 258
Cdd:PRK03359 234 RIVIEGDGEEQIAAFAENLRK 254
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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