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Conserved domains on  [gi|499399008|ref|WP_011086475|]
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MULTISPECIES: RNA polymerase sigma factor [Bradyrhizobium]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK12538 super family cl31386
RNA polymerase sigma factor; Provisional
1-232 1.23e-140

RNA polymerase sigma factor; Provisional


The actual alignment was detected with superfamily member PRK12538:

Pssm-ID: 139048 [Multi-domain]  Cd Length: 233  Bit Score: 393.07  E-value: 1.23e-140
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008   1 MSFAVDVFARAEAEIATTITSE--ANAPVIASASIAPDGEPVAaDVVFDEDSELLDRLAADDETAFRMLVERHIDRAYAI 78
Cdd:PRK12538   1 MNYALDVLAPAEAAPATTAPSPivAEAPDAASVSIVPDPPPVA-DAVFDEDEELLDRLATDDEAAFRLLVERHIDRAYAI 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  79 ALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGRAKFSTWLYRVISNRCIDLRRKPRTENVDTVPEVADGRPDASRVIERN 158
Cdd:PRK12538  80 ALRIVGNRADAEDVVQDTMLKVWTHRGRWQHGRAKFSTWLYRVVSNRCIDLRRKPRTENVDAVPEVADGKPDAVSVIERN 159
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499399008 159 ELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKRGRQQLRQLLRRHERDIRTAFTDC 232
Cdd:PRK12538 160 ELSDLLEAAMQRLPEQQRIAVILSYHENMSNGEIAEVMDTTVAAVESLLKRGRQQLRDLLRRHERDIRHAFTDC 233
 
Name Accession Description Interval E-value
PRK12538 PRK12538
RNA polymerase sigma factor; Provisional
1-232 1.23e-140

RNA polymerase sigma factor; Provisional


Pssm-ID: 139048 [Multi-domain]  Cd Length: 233  Bit Score: 393.07  E-value: 1.23e-140
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008   1 MSFAVDVFARAEAEIATTITSE--ANAPVIASASIAPDGEPVAaDVVFDEDSELLDRLAADDETAFRMLVERHIDRAYAI 78
Cdd:PRK12538   1 MNYALDVLAPAEAAPATTAPSPivAEAPDAASVSIVPDPPPVA-DAVFDEDEELLDRLATDDEAAFRLLVERHIDRAYAI 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  79 ALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGRAKFSTWLYRVISNRCIDLRRKPRTENVDTVPEVADGRPDASRVIERN 158
Cdd:PRK12538  80 ALRIVGNRADAEDVVQDTMLKVWTHRGRWQHGRAKFSTWLYRVVSNRCIDLRRKPRTENVDAVPEVADGKPDAVSVIERN 159
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499399008 159 ELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKRGRQQLRQLLRRHERDIRTAFTDC 232
Cdd:PRK12538 160 ELSDLLEAAMQRLPEQQRIAVILSYHENMSNGEIAEVMDTTVAAVESLLKRGRQQLRDLLRRHERDIRHAFTDC 233
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
48-210 3.44e-48

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 156.69  E-value: 3.44e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  48 EDSELLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQhGRAKFSTWLYRVISNRCI 127
Cdd:COG1595    3 SDEELLERLRAGDEAAFEELYERYRPRLYRYARRLLGDRADAEDLVQETFLRLWRKLDSFR-GRGSFRAWLYRIARNLAI 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 128 DLRRKPRTENV---DTVPEVADGRPDASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVE 204
Cdd:COG1595   82 DHLRKRRRRRElldELAEELPDEAADPEEALEAEELLEALLAALERLPPRQREVLVLRYLEGLSYAEIAEILGISEGTVK 161

                 ....*.
gi 499399008 205 SLLKRG 210
Cdd:COG1595  162 SRLSRA 167
Sig70_bacteroi1 TIGR02985
RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors ...
62-210 6.27e-46

RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors are members of the sigma-70 family (TIGR02937) and are found primarily in the genus Bacteroides. This family appears to have resulted from a lineage-specific expansion as B. thetaiotaomicron VPI-5482, Bacteroides forsythus ATCC 43037, Bacteroides fragilis YCH46 and Bacteroides fragilis NCTC 9343 contain 25, 12, 24 and 23 members, respectively. There are currentlyonly two known members of this family outside of the Bacteroides, in Rhodopseudomonas and Bradyrhizobium.


Pssm-ID: 274376 [Multi-domain]  Cd Length: 161  Bit Score: 150.02  E-value: 6.27e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008   62 TAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWqHGRAKFSTWLYRVISNRCID-LRRKPRTENVDT 140
Cdd:TIGR02985   1 EAFEQLYRRYYPKLCAFARRYVKDEEDAEDIVQDVFLKLWENRETL-EISESIKAYLFTIVKNRCLNyLRHKQVEEKYQE 79
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499399008  141 vpEVADGRPDASRV------IERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKRG 210
Cdd:TIGR02985  80 --ELAEIEERELSEadpeeeLEAKELEEIIEEAIEKLPEQCREIFILSRFEGLSNKEIAEELGISVKTVEYHITKA 153
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
67-132 2.18e-18

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 76.09  E-value: 2.18e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499399008   67 LVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGRA-KFSTWLYRVISNRCIDLRRK 132
Cdd:pfam04542   1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFDPERGvSFSTWLYTIIRNAIIDYLRK 67
CAS_III-E_sigma NF041236
type III-E CRISPR-associated RpoE-like sigma factor;
86-197 7.83e-09

type III-E CRISPR-associated RpoE-like sigma factor;


Pssm-ID: 469138 [Multi-domain]  Cd Length: 192  Bit Score: 53.54  E-value: 7.83e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  86 AADAEDVVQDSMLKIWSHRGRWQhGR--AKFSTWLYRVISNRCIDLRRKPRTENVDTVPEV---ADGRPDASRVIERNEL 160
Cdd:NF041236  47 PEDREDILSETVEAVQRGIGKFE-GRrgAKFSTWVWRIFRNKRVDYFRKKYKKKEYSLPLEgaeDDQEEEPEDDIEEMFA 125
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 499399008 161 NGMLEEAM-QRLPEQQR--IAVILSYHEDMSNG----EIAEVMD 197
Cdd:NF041236 126 AEDIIECLkKKVDDGETgcIRLLLDLYRWFKEGltqkEMAESYG 169
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
163-210 7.07e-08

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 47.87  E-value: 7.07e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 499399008 163 MLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKRG 210
Cdd:cd06171    3 RLEEALDKLPEREREVILLRFGEGLSYEEIAEILGISRSTVRQRLHRA 50
 
Name Accession Description Interval E-value
PRK12538 PRK12538
RNA polymerase sigma factor; Provisional
1-232 1.23e-140

RNA polymerase sigma factor; Provisional


Pssm-ID: 139048 [Multi-domain]  Cd Length: 233  Bit Score: 393.07  E-value: 1.23e-140
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008   1 MSFAVDVFARAEAEIATTITSE--ANAPVIASASIAPDGEPVAaDVVFDEDSELLDRLAADDETAFRMLVERHIDRAYAI 78
Cdd:PRK12538   1 MNYALDVLAPAEAAPATTAPSPivAEAPDAASVSIVPDPPPVA-DAVFDEDEELLDRLATDDEAAFRLLVERHIDRAYAI 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  79 ALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGRAKFSTWLYRVISNRCIDLRRKPRTENVDTVPEVADGRPDASRVIERN 158
Cdd:PRK12538  80 ALRIVGNRADAEDVVQDTMLKVWTHRGRWQHGRAKFSTWLYRVVSNRCIDLRRKPRTENVDAVPEVADGKPDAVSVIERN 159
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499399008 159 ELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKRGRQQLRQLLRRHERDIRTAFTDC 232
Cdd:PRK12538 160 ELSDLLEAAMQRLPEQQRIAVILSYHENMSNGEIAEVMDTTVAAVESLLKRGRQQLRDLLRRHERDIRHAFTDC 233
PRK05602 PRK05602
RNA polymerase sigma factor; Reviewed
47-210 1.07e-56

RNA polymerase sigma factor; Reviewed


Pssm-ID: 235530 [Multi-domain]  Cd Length: 186  Bit Score: 178.31  E-value: 1.07e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  47 DEDSELLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGRAKFSTWLYRVISNRC 126
Cdd:PRK05602   5 DPDEELLARVAAGDPAAFRVLVARKLPRLLALATRMLGDPAEAEDVAQETFLRIWKQAPSWRPGEARFDTWLHRVVLNLC 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 127 IDLRRKPRTENVDTVPEVADGRPDASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESL 206
Cdd:PRK05602  85 YDRLRRRREVPVEDAPDVPDPAPGPDAGLEARQRARRVEQALAALPERQREAIVLQYYQGLSNIEAAAVMDISVDALESL 164

                 ....
gi 499399008 207 LKRG 210
Cdd:PRK05602 165 LARG 168
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
48-210 3.44e-48

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 156.69  E-value: 3.44e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  48 EDSELLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQhGRAKFSTWLYRVISNRCI 127
Cdd:COG1595    3 SDEELLERLRAGDEAAFEELYERYRPRLYRYARRLLGDRADAEDLVQETFLRLWRKLDSFR-GRGSFRAWLYRIARNLAI 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 128 DLRRKPRTENV---DTVPEVADGRPDASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVE 204
Cdd:COG1595   82 DHLRKRRRRRElldELAEELPDEAADPEEALEAEELLEALLAALERLPPRQREVLVLRYLEGLSYAEIAEILGISEGTVK 161

                 ....*.
gi 499399008 205 SLLKRG 210
Cdd:COG1595  162 SRLSRA 167
Sig70_bacteroi1 TIGR02985
RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors ...
62-210 6.27e-46

RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors are members of the sigma-70 family (TIGR02937) and are found primarily in the genus Bacteroides. This family appears to have resulted from a lineage-specific expansion as B. thetaiotaomicron VPI-5482, Bacteroides forsythus ATCC 43037, Bacteroides fragilis YCH46 and Bacteroides fragilis NCTC 9343 contain 25, 12, 24 and 23 members, respectively. There are currentlyonly two known members of this family outside of the Bacteroides, in Rhodopseudomonas and Bradyrhizobium.


Pssm-ID: 274376 [Multi-domain]  Cd Length: 161  Bit Score: 150.02  E-value: 6.27e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008   62 TAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWqHGRAKFSTWLYRVISNRCID-LRRKPRTENVDT 140
Cdd:TIGR02985   1 EAFEQLYRRYYPKLCAFARRYVKDEEDAEDIVQDVFLKLWENRETL-EISESIKAYLFTIVKNRCLNyLRHKQVEEKYQE 79
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499399008  141 vpEVADGRPDASRV------IERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKRG 210
Cdd:TIGR02985  80 --ELAEIEERELSEadpeeeLEAKELEEIIEEAIEKLPEQCREIFILSRFEGLSNKEIAEELGISVKTVEYHITKA 153
PRK12524 PRK12524
RNA polymerase sigma factor; Provisional
36-210 1.48e-41

RNA polymerase sigma factor; Provisional


Pssm-ID: 183573 [Multi-domain]  Cd Length: 196  Bit Score: 140.02  E-value: 1.48e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  36 DGEPVAADVvfdEDSELLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGRAKFS 115
Cdd:PRK12524   3 MPFDALSDV---SDEALLVLYANGDPAAARALTLRLAPRALAVATRVLGDRAEAEDVTQEAMLRLWRIAPDWRQGEARVS 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 116 TWLYRVISNRCIDLRRKPRTENV--DTVPEVADGRPDASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIA 193
Cdd:PRK12524  80 TWLYRVVCNLCTDRLRRRRRASVdlDDAPEPADAAPGAEEALIEGDRMRALDAALAALPERQRQAVVLRHIEGLSNPEIA 159
                        170
                 ....*....|....*..
gi 499399008 194 EVMDSTVAAVESLLKRG 210
Cdd:PRK12524 160 EVMEIGVEAVESLTARG 176
sigma70-ECF TIGR02937
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the ...
63-210 6.47e-36

RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.


Pssm-ID: 274357 [Multi-domain]  Cd Length: 158  Bit Score: 124.38  E-value: 6.47e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008   63 AFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQhGRAKFSTWLYRVISNRCIDLRRKPR--TENVDT 140
Cdd:TIGR02937   2 AFEELYERYLPLVYRYARRYLGDDADAEDLVQEAFLKLLEALDRFD-PEGSFKAWLFRIARNLILDYLRRKRrlRRELDL 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  141 VPEVADGRPDASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKRG 210
Cdd:TIGR02937  81 LEELLDSDPSPEEELEQEEEREALREALEKLPEREREVLVLRYLEGLSYKEIAEILGISVGTVKRRLKRA 150
PRK09652 PRK09652
RNA polymerase sigma factor RpoE; Provisional
53-210 8.39e-32

RNA polymerase sigma factor RpoE; Provisional


Pssm-ID: 236608 [Multi-domain]  Cd Length: 182  Bit Score: 114.52  E-value: 8.39e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  53 LDRLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQhGRAKFSTWLYRVISNRCID---- 128
Cdd:PRK09652   1 VERVQRGDRAAFALLVRRYQPRVKRLLSRLTRDPADAEDLVQETFIKAYRALHSFR-GGAAFYTWLYRIARNTAINylrk 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 129 LRRKPRTENVDT-------VPEVADGRPDASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVA 201
Cdd:PRK09652  80 QGRRPPASDVDAeeaedfdLADALRDISTPENELLSAELEQRVRAAIESLPEELRTAITLREIEGLSYEEIAEIMGCPIG 159

                 ....*....
gi 499399008 202 AVESLLKRG 210
Cdd:PRK09652 160 TVRSRIFRA 168
PRK09641 PRK09641
RNA polymerase sigma factor SigW; Provisional
49-214 7.05e-29

RNA polymerase sigma factor SigW; Provisional


Pssm-ID: 182012 [Multi-domain]  Cd Length: 187  Bit Score: 107.09  E-value: 7.05e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  49 DSELLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGRaKFSTWLYRVISNRCID 128
Cdd:PRK09641   5 IKRLIKQVKKGDQNAFAELVDLYKDKIYQLCYRMLGNRHEAEDAAQEAFIRAYVNIDSYDINR-KFSTWLYRIATNLTID 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 129 -LR-RKPR---------TENVDTVPEVADGRPDASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMD 197
Cdd:PRK09641  84 rLRkRKPDyyldaevagTEGLTMYSQLAADDALPEEQVVSLELQETIQEAILQLPEKYRTVIVLKYIEDLSLKEISEILD 163
                        170
                 ....*....|....*..
gi 499399008 198 STVAAVESLLKRGRQQL 214
Cdd:PRK09641 164 LPVGTVKTRIHRGREAL 180
PRK11924 PRK11924
RNA polymerase sigma factor; Provisional
50-210 8.63e-28

RNA polymerase sigma factor; Provisional


Pssm-ID: 183384 [Multi-domain]  Cd Length: 179  Bit Score: 103.90  E-value: 8.63e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  50 SELLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRgRWQHGRAKFSTWLYRVISNRCIDL 129
Cdd:PRK11924   1 GQLMPVDATGDKEAFSELFRPHAPDLLRYARRQLGDRALAEDAVQEAFLRAWRKA-DLFNGKGSARTWLLTIARNVCYDL 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 130 RRKPRTENVDTV-----PEVADGRPDASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVE 204
Cdd:PRK11924  80 LRRRRREKAVLSddalePEFAETAETPEAALLAKDDLARIDRCLDALPVKQREVFLLRYVEGLSYREIAEILGVPVGTVK 159

                 ....*.
gi 499399008 205 SLLKRG 210
Cdd:PRK11924 160 SRLRRA 165
PRK12513 PRK12513
RNA polymerase sigma factor; Provisional
49-208 7.50e-26

RNA polymerase sigma factor; Provisional


Pssm-ID: 183566 [Multi-domain]  Cd Length: 194  Bit Score: 99.38  E-value: 7.50e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  49 DSELLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHgRAKFSTWLYRVISNRCID 128
Cdd:PRK12513  13 DEALMLRYRAGDAAAFEALYARHRTGLYRFLLRLARDRALAEDIFQETWLRVIRARAQYQP-RARFRTWLYQIARNLLID 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 129 ------LRRKPRTENVDTVPEVADGRPDASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAA 202
Cdd:PRK12513  92 hwrrhgARQAPSLDADEQLHALADDGAAPEQQLSLFRDRRRLQAALETLPDEQREVFLLREHGDLELEEIAELTGVPEET 171

                 ....*.
gi 499399008 203 VESLLK 208
Cdd:PRK12513 172 VKSRLR 177
PRK09643 PRK09643
RNA polymerase sigma factor SigM; Reviewed
49-210 8.41e-25

RNA polymerase sigma factor SigM; Reviewed


Pssm-ID: 236604 [Multi-domain]  Cd Length: 192  Bit Score: 96.70  E-value: 8.41e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  49 DSELLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQhGRAKFSTWLYRVISNRCID 128
Cdd:PRK09643  14 DAELLAAHVAGDRYAFGELFRRHHRRLWAVARRTSGTREDAADALQDAMLSAHRAAGSFR-GDAAVSSWLHRIVVNACLD 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 129 LRRKPRTENVDTVPEVADGRPDASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLK 208
Cdd:PRK09643  93 RLRRAKARPTVPLDDVYPVAQLERDPTARVETALAVQRALMRLPVEQRAALVAVDMQGYSVADAARMLGVAEGTVKSRCA 172

                 ..
gi 499399008 209 RG 210
Cdd:PRK09643 173 RG 174
PRK08241 PRK08241
RNA polymerase subunit sigma-70;
51-209 1.59e-22

RNA polymerase subunit sigma-70;


Pssm-ID: 236196 [Multi-domain]  Cd Length: 339  Bit Score: 93.85  E-value: 1.59e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  51 ELLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQhGRAKFSTWLYRVISNRCID-L 129
Cdd:PRK08241   8 ALLARAAAGDRDAFAALVEPHRRELLAHCYRMLGSVHDAEDAVQETLLRAWRGYDRFE-GRSSLRTWLYRIATNVCLDaL 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 130 RRKPR--------------TENVDTVPEVA------DGRPD------ASRVIERNELNGMLEEAMQRLPEQQRIAVILSY 183
Cdd:PRK08241  87 EGRARrplptdlgapaadpVDELVERPEVPwlepypDALLDpaaadpAARVVARESVRLAFVAALQHLPPRQRAVLILRD 166
                        170       180
                 ....*....|....*....|....*.
gi 499399008 184 HEDMSNGEIAEVMDSTVAAVESLLKR 209
Cdd:PRK08241 167 VLGWSAAEVAELLDTSVAAVNSALQR 192
PRK11922 PRK11922
RNA polymerase sigma factor; Provisional
33-209 3.50e-21

RNA polymerase sigma factor; Provisional


Pssm-ID: 237024 [Multi-domain]  Cd Length: 231  Bit Score: 88.10  E-value: 3.50e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  33 IAPDGEPVAADVVFDEDSELLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQhGRA 112
Cdd:PRK11922   1 MTTAPASRPPPLSAASDRELVARVLAGDEAAFEALMRRHNRRLYRTARAILRNDAEAEDVVQEAYLRAFRALGTFR-GDA 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 113 KFSTWLYRVISNRCID-LRRKPRTENVDTVP-----------EVADGRPDASRVIERNELNGMLEEAMQRLPEQQRIAVI 180
Cdd:PRK11922  80 SLSTWLSRIVLNEALGrLRRRRRLVNLAEMVmastiaggertPLADPAEDPERAAARREIRALLERAIDALPDAFRAVFV 159
                        170       180
                 ....*....|....*....|....*....
gi 499399008 181 LSYHEDMSNGEIAEVMDSTVAAVESLLKR 209
Cdd:PRK11922 160 LRVVEELSVEETAQALGLPEETVKTRLHR 188
PRK09638 PRK09638
RNA polymerase sigma factor SigY; Reviewed
48-210 7.98e-20

RNA polymerase sigma factor SigY; Reviewed


Pssm-ID: 182010 [Multi-domain]  Cd Length: 176  Bit Score: 83.15  E-value: 7.98e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  48 EDSELLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQhGRAKFSTWLYRVISNRCI 127
Cdd:PRK09638   4 DEKELIQKAKKGDDAALTTLFQQHYSFLYKYLLKLTLDPDLAEDLVQETMLKAIENLSSFQ-GRSKFSTWLISIASRLYK 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 128 D-LRRKPRTENVDTvpEVADGRPDASRV---IERNELNGMLeEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAV 203
Cdd:PRK09638  83 DhLRKQKREKLRLQ--RAKEETLRKEKWeaaIKGAEWSEML-DALSKLDPEFRAPVILKHYYGYTYEEIAKMLNIPEGTV 159

                 ....*..
gi 499399008 204 ESLLKRG 210
Cdd:PRK09638 160 KSRVHHG 166
PRK12515 PRK12515
RNA polymerase sigma factor; Provisional
49-207 1.95e-19

RNA polymerase sigma factor; Provisional


Pssm-ID: 183567 [Multi-domain]  Cd Length: 189  Bit Score: 82.47  E-value: 1.95e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  49 DSELLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQhGRAKFSTWLYRVISNRCID 128
Cdd:PRK12515   9 DEMLLARIAQGDRTAMQTLYGRHHVRVYRFGLRLVRDEQTAEDLVSEVFLDVWRQAGQFE-GRSQVSTWLLSIARFKALS 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 129 LRRKPRTENVD--TVPEVADGRPDASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESL 206
Cdd:PRK12515  88 ALRRRKHEEIDdeAAAAIEDGADTPEVALQKSDTSAALRACLAKLSPAHREIIDLVYYHEKSVEEVGEIVGIPESTVKTR 167

                 .
gi 499399008 207 L 207
Cdd:PRK12515 168 M 168
PRK12519 PRK12519
RNA polymerase sigma factor; Provisional
37-210 1.96e-19

RNA polymerase sigma factor; Provisional


Pssm-ID: 237125 [Multi-domain]  Cd Length: 194  Bit Score: 82.42  E-value: 1.96e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  37 GEPVAADVVFDEDSELLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGrWQHGRAKFST 116
Cdd:PRK12519   4 GDSAPTSLSSRSDAELFSALKAGQSAALGVLYDRHAGLVYGLALKILGNSQEAEDLTQEIFLSLWRKSS-YDPKRGSLSS 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 117 WLYRVISNRCID-LR-RKPRTENVDTVPEVADGRPDASRVIER---NELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGE 191
Cdd:PRK12519  83 YLLTLTRSRAIDrLRsRRSRQRLLERWQQELLGEASEDTPLEQaslAERSQRVQTALAQLPESQRQVLELAYYEGLSQSE 162
                        170
                 ....*....|....*....
gi 499399008 192 IAEVMDSTVAAVESLLKRG 210
Cdd:PRK12519 163 IAKRLGIPLGTVKARARQG 181
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
67-132 2.18e-18

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 76.09  E-value: 2.18e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499399008   67 LVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGRA-KFSTWLYRVISNRCIDLRRK 132
Cdd:pfam04542   1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFDPERGvSFSTWLYTIIRNAIIDYLRK 67
algU PRK11923
RNA polymerase sigma factor AlgU; Provisional
47-209 3.12e-18

RNA polymerase sigma factor AlgU; Provisional


Pssm-ID: 171347 [Multi-domain]  Cd Length: 193  Bit Score: 79.46  E-value: 3.12e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  47 DEDSELLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQhGRAKFSTWLYRVI---- 122
Cdd:PRK11923   5 EEDQQLVERVQRGDKRAFDLLVLKYQHKILGLIVRFVHDTAEAQDVAQEAFIKAYRALGNFR-GDSAFYTWLYRIAinta 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 123 SNRCIDLRRKPRTENVDTV-PEVADGR------PDASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEV 195
Cdd:PRK11923  84 KNHLVSRGRRPPDSDVSSEdAEFYDGDhalkdiESPERALLRDEIEGTVHRTIQQLPEDLRTALTLREFDGLSYEDIASV 163
                        170
                 ....*....|....
gi 499399008 196 MDSTVAAVESLLKR 209
Cdd:PRK11923 164 MQCPVGTVRSRIFR 177
Sig70_famx3 TIGR02954
RNA polymerase sigma-70 factor, TIGR02954 family; This group of sigma factors are members of ...
49-210 5.40e-18

RNA polymerase sigma-70 factor, TIGR02954 family; This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building, bidirectional best hits and one-to-a-genome distribution, to represent a conserved family. This family is found in certain Bacillus and Clostridium species.


Pssm-ID: 213752 [Multi-domain]  Cd Length: 169  Bit Score: 78.21  E-value: 5.40e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008   49 DSELLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGRAkFSTWLYRVISNRCID 128
Cdd:TIGR02954   3 DEELVKKAKRGNKPAFESLIKKHKEKLYKTAFIYVKNEHDALDVIQETVYKAYLSIDKLKHPKY-FNTWLTRILINECID 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  129 LRRKPRtenvDTVPEvadGRPDASRVIE-----RNELNgmLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAV 203
Cdd:TIGR02954  82 LLKKKK----KVIPF---DPNTSIEKGEcethaDSRLD--LYKAIDTLNDKYQTAIILRYYHDLTIKEIAEVMNKPEGTV 152

                  ....*..
gi 499399008  204 ESLLKRG 210
Cdd:TIGR02954 153 KTYLHRA 159
Sig70_famx2 TIGR02952
RNA polymerase sigma-70 factor, TIGR02952 family; This group of sigma factors are members of ...
52-209 6.93e-18

RNA polymerase sigma-70 factor, TIGR02952 family; This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building, bidirectional best hits and one-to-a-genome distribution, to represent a conserved family. This family is found in a limited number of Gram-positive bacterial lineages.


Pssm-ID: 131997 [Multi-domain]  Cd Length: 170  Bit Score: 77.92  E-value: 6.93e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008   52 LLDRLAADDETAFRMLVERHIDRAYA-IALRiVGNAADAEDVVQDSMLKIWSHRGRWQHGRAKFSTWLYRVISNRCID-- 128
Cdd:TIGR02952   1 LLERAQDREEDAFARIYETYSDRVYRyIYYR-VGCKYTAEDLTSEVFERVLRKIDSFKEQKNSFEAWLFTIARNVVNDyf 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  129 --LRRKPRTeNVDTVPEVADGRPDASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESL 206
Cdd:TIGR02952  80 rgSKRHPLF-SLDVFKELLSNEPNPEEAILKEEANEKLLKALKILTPKQQHVIALRFGQNLPIAEVARILGKTEGAVKIL 158

                  ...
gi 499399008  207 LKR 209
Cdd:TIGR02952 159 QFR 161
SigE-fam_strep TIGR02983
RNA polymerase sigma-70 factor, sigma-E family; This group of similar sigma-70 factors ...
57-210 2.09e-17

RNA polymerase sigma-70 factor, sigma-E family; This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.


Pssm-ID: 132028 [Multi-domain]  Cd Length: 162  Bit Score: 76.27  E-value: 2.09e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008   57 AADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWshrGRWQHGRAKFST--WLYRVISNRCIDL--RRK 132
Cdd:TIGR02983   1 RSATEEEFTAFVAARYPRLLRTAYLLTGDPHEAEDLVQEALVRTY---VRWDRIRDPDAPdaYVRRVLVNLARSRwrRRR 77
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499399008  133 PRTENVDTVPEVADGRPDAsrvieRNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKRG 210
Cdd:TIGR02983  78 LLELPTRELPDAAAPDPAP-----DVALRAALARALRRLPARQRAVVVLRYYEDLSEAQVAEALGISVGTVKSRLSRA 150
PRK09647 PRK09647
RNA polymerase sigma factor SigE; Reviewed
67-210 2.66e-16

RNA polymerase sigma factor SigE; Reviewed


Pssm-ID: 236606 [Multi-domain]  Cd Length: 203  Bit Score: 74.44  E-value: 2.66e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  67 LVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGraKFSTWLYRVISNRCIDLRRKPRTENVDTVPEVAD 146
Cdd:PRK09647  33 LVRQHADRVYRLAYRLSGNQHDAEDLTQETFIRVFRSLQNYQPG--TFEGWLHRITTNLFLDMVRRRARIRMEALPEDYD 110
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499399008 147 ----GRPDASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKRG 210
Cdd:PRK09647 111 rvpgDEPNPEQIYHDARLDPDLQAALDSLPPEFRAAVVLCDIEGLSYEEIAATLGVKLGTVRSRIHRG 178
PRK12514 PRK12514
RNA polymerase sigma factor; Provisional
47-209 4.91e-16

RNA polymerase sigma factor; Provisional


Pssm-ID: 105710 [Multi-domain]  Cd Length: 179  Bit Score: 73.32  E-value: 4.91e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  47 DEDSELLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGRAKFSTWLYRVISNRC 126
Cdd:PRK12514   4 DDIEKLIVRVSLGDRDAFSSLYDATSAKLFGICLRVLKDRSEAEEALQDVYVKIWTKADRFAVSGLSPMTWLITIARNHA 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 127 ID-LR-RKPRTENVDTVPEVADGRPDA-SRVIERNElNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAV 203
Cdd:PRK12514  84 IDrLRaRKAVAVDIDEAHDLADPSPGPeAEVIAGDE-GQRIDACLEELEKDRAAAVRRAYLEGLSYKELAERHDVPLNTM 162

                 ....*.
gi 499399008 204 ESLLKR 209
Cdd:PRK12514 163 RTWLRR 168
SigZ TIGR02959
RNA polymerase sigma factor, SigZ family; This family of RNA polymerase sigma factors is a ...
83-213 3.53e-15

RNA polymerase sigma factor, SigZ family; This family of RNA polymerase sigma factors is a member of the Sigma-70 subfamily (TIGR02937). One of these is designated as SigZ in B. subtilis (Swiss_Prot: SIGZ_BACSU). Interestingly, this group has a very sporatic distribution, B. subtilis, for instance, being the only sequenced strain of Bacilli with a member. Dechloromonas aromatica RCB appears to have two of these sigma factors. A member appears on a plasmid found in Photobacterium profundum SS9 and Vibrio fischeri ES114 (where a second one is chromosomally encoded).


Pssm-ID: 132004 [Multi-domain]  Cd Length: 170  Bit Score: 70.47  E-value: 3.53e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008   83 VGNAADAEDVVQDSMLKIWSHRGRWQHGrAKFSTWLYRVISNRCIDLRRKPRTENVDTVPEVAdgrPDASRVIE-RNELN 161
Cdd:TIGR02959  16 VSDASDVEDLLQEVFIKIHRNLPSLKDG-QKIQSWLYQIARNTIIDFYRSKSRSVELPESLLA---ADSAREETfVKELS 91
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 499399008  162 GMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKRGRQQ 213
Cdd:TIGR02959  92 QCIPPMIKELPDEYREAIRLTELEGLSQQEIAEKLGLSLSGAKSRVQRGRKK 143
PRK09640 PRK09640
RNA polymerase sigma factor SigX; Reviewed
49-209 4.32e-15

RNA polymerase sigma factor SigX; Reviewed


Pssm-ID: 236603 [Multi-domain]  Cd Length: 188  Bit Score: 70.74  E-value: 4.32e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  49 DSELLDRLAAD---DETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQhGRAKFSTWLYRVISNR 125
Cdd:PRK09640  10 DEELVARVHVElfhVTRAYEELMRRYQRTLFNVCARYLGNDRDADDVCQEVMLKVLYGLKNFE-GKSKFKTWLYSITYNE 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 126 CIDLRRKPRTENVDTVPEVADGRPDAS-RVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVE 204
Cdd:PRK09640  89 CITQYRKERRKRRLMDALSLDPLEEASeEKAPKPEERGGLDRWLVHVNPIDREILVLRFVAELEFQEIADIMHMGLSATK 168

                 ....*
gi 499399008 205 SLLKR 209
Cdd:PRK09640 169 MRYKR 173
PRK12518 PRK12518
RNA polymerase sigma factor; Provisional
52-207 6.02e-15

RNA polymerase sigma factor; Provisional


Pssm-ID: 237124 [Multi-domain]  Cd Length: 175  Bit Score: 70.13  E-value: 6.02e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  52 LLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAAdAEDVVQDSMLKIWSHRGRWQHgRAKFSTWLYRVISNRCIDLRR 131
Cdd:PRK12518   1 LILRCQRGDRQSFRQLYRRYQQKVRSTLYQLCGREL-LDDLVQEVFLRVWKGLPKLRN-PAYFSTWLYRITWNVATDARR 78
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499399008 132 ---KPRTENVDTVPEVADGRPDASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLL 207
Cdd:PRK12518  79 qfaQRPSRIQDDSLNDQPSRPSDTPDLMQLHYQDLVQQGLQTLSLEHRAVLVLHDLEDLPQKEIAEILNIPVGTVKSRL 157
PRK09645 PRK09645
ECF RNA polymerase sigma factor SigL;
57-197 6.46e-15

ECF RNA polymerase sigma factor SigL;


Pssm-ID: 236605 [Multi-domain]  Cd Length: 173  Bit Score: 70.11  E-value: 6.46e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  57 AADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGRAKFSTWLYRVISNRCIDLRRKPRTE 136
Cdd:PRK09645   4 ATAEAALMRALYDEHAAPLWRYALRLTGDRARAEDVVQETLLRAWQHPEVLADTGRSARAWLFTVARNLVIDERRSARAR 83
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 499399008 137 NVDTVPEV-ADGRPDASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMD 197
Cdd:PRK09645  84 PVEGGDDVlGVPEQSAPDEVDRALDRLLVADALAQLSPEHRAVLVRSYYRGWSTAQIAADLG 145
PRK12534 PRK12534
RNA polymerase sigma factor; Provisional
47-210 7.85e-15

RNA polymerase sigma factor; Provisional


Pssm-ID: 183576 [Multi-domain]  Cd Length: 187  Bit Score: 70.08  E-value: 7.85e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  47 DEDSELLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGRAKFSTWLYRVISNRC 126
Cdd:PRK12534  10 DETGRLLTATAGGDRHAFEALYRQTSPKLFGVCLRMIPQRAEAEEVLQDVFTLIWHKAGQFDPSRARGLTWLAMIARNKA 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 127 ID-LR-RKPRTENV--DTVPEV-ADGRPDASRViERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVA 201
Cdd:PRK12534  90 IDhLRaNAPQRRNValDDAGELrAADASPLERT-ERASTRRRIDHCLAELEPPRSELIRTAFFEGITYEELAARTDTPIG 168

                 ....*....
gi 499399008 202 AVESLLKRG 210
Cdd:PRK12534 169 TVKSWIRRG 177
PRK12537 PRK12537
RNA polymerase sigma factor; Provisional
46-210 9.79e-14

RNA polymerase sigma factor; Provisional


Pssm-ID: 171568 [Multi-domain]  Cd Length: 182  Bit Score: 67.11  E-value: 9.79e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  46 FDEDSELLdRLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGRAKFSTWLYRVISNR 125
Cdd:PRK12537   8 FDYEACLL-ACARGDRRALQALYQQESARLLGVARRIVRDRALAEDIVHDAFIKIWTGAASFDPARGSARGWIYSVTRHL 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 126 CIDLRRKPRTENV--DTVPEVADGRPDASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAV 203
Cdd:PRK12537  87 ALNVLRDTRREVVldDDAEETAQTLHEIIDDFDLWANSGKIHRCLEQLEPARRNCILHAYVDGCSHAEIAQRLGAPLGTV 166

                 ....*..
gi 499399008 204 ESLLKRG 210
Cdd:PRK12537 167 KAWIKRS 173
PRK09415 PRK09415
RNA polymerase factor sigma C; Reviewed
83-212 1.69e-13

RNA polymerase factor sigma C; Reviewed


Pssm-ID: 181835 [Multi-domain]  Cd Length: 179  Bit Score: 66.31  E-value: 1.69e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  83 VGNAADAEDVVQDSMLKIWSHRGRWQhGRAKFSTWLYRVISNRCIDLRRKPRTENVDTVPEVADGRPDASR-----VIER 157
Cdd:PRK09415  37 VKNKEVAEDLTQEIFVKCYKSLHTYK-GKSSLKTWLYRIAINHCKDYLKSWHNKKVIVTEDIFTYMESQKEsveeeVIQN 115
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 499399008 158 NELNGMLEEAMQrLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKRGRQ 212
Cdd:PRK09415 116 AEDERLASAVMS-LPIKYREVIYLFYYEELSIKEIAEVTGVNENTVKTRLKKAKE 169
PRK09637 PRK09637
RNA polymerase sigma factor SigZ; Provisional
83-213 2.48e-13

RNA polymerase sigma factor SigZ; Provisional


Pssm-ID: 236601 [Multi-domain]  Cd Length: 181  Bit Score: 65.78  E-value: 2.48e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  83 VGNAADAEDVVQDSMLKIWSHRGRWQHGrAKFSTWLYRVISNRCIDLRRKPRTENVDTVPEVADGRPDASRVieRNELNG 162
Cdd:PRK09637  22 VSNEADVDDLLQEVLIKTHSNLHSLKDG-SSIKSWLYQIANNTIIDFYRKKNRSEELPDDLLFEDEEREENA--KKELAP 98
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 499399008 163 MLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKRGRQQ 213
Cdd:PRK09637  99 CLRPFIDALPEKYAEALRLTELEGLSQKEIAEKLGLSLSGAKSRVQRGRVK 149
PRK12531 PRK12531
RNA polymerase sigma factor; Provisional
48-208 2.50e-13

RNA polymerase sigma factor; Provisional


Pssm-ID: 105726 [Multi-domain]  Cd Length: 194  Bit Score: 66.11  E-value: 2.50e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  48 EDSELLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGRAKFSTWLYRVISNRCI 127
Cdd:PRK12531  13 EWLECMEKVKSRDKQAFALVFSYYAPKLKQFAMKHVGNEQVAMEMVQETMSTVWQKAHLFDGQKSALSTWIYTIIRNLCF 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 128 DLRRKPRTENV-----DTVPEvaDGRPdASRVIERNELNGMLEEA----MQRLPEQQRIAVILSYHEDMSNGEIAEVMDS 198
Cdd:PRK12531  93 DLLRKQKGKDLhihadDIWPS--DYYP-PDLVDHYSPEQDMLKEQvmkfLDRLPKAQRDVLQAVYLEELPHQQVAEMFDI 169
                        170
                 ....*....|
gi 499399008 199 TVAAVESLLK 208
Cdd:PRK12531 170 PLGTVKSRLR 179
PRK12522 PRK12522
RNA polymerase sigma factor; Provisional
61-210 2.13e-12

RNA polymerase sigma factor; Provisional


Pssm-ID: 183571 [Multi-domain]  Cd Length: 173  Bit Score: 63.35  E-value: 2.13e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  61 ETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWS--HRGRWQHgraKFSTWLYRVISNRCID-LRRKPRTEN 137
Cdd:PRK12522   2 EEKVEELIDIYKQQIYSLCYKLAKTKEDAEDIFQETWIKVFSsrHQLSYVE---NYKKWITTICVRTFYDfYRKKKRWKD 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 138 V--DTVPEVADGR---PDASRVIE---RNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKR 209
Cdd:PRK12522  79 RilDLFHKEDGGEiefADDVNISEefiQKVEAEMIREVIQLLNEKYKTVLVLYYYEQYSYKEMSEILNIPIGTVKYRLNY 158

                 .
gi 499399008 210 G 210
Cdd:PRK12522 159 A 159
SigM_subfam TIGR02950
RNA polymerase sigma factor, SigM family; This family of RNA polymerase sigma factors is a ...
76-214 1.94e-11

RNA polymerase sigma factor, SigM family; This family of RNA polymerase sigma factors is a member of the Sigma-70 subfamily (TIGR02937) and is restricted to certain lineages of the order Bacillales. This family encompasses at least two distinct sigma factors as two proteins are found in each of B. anthracis, B. subtilis subsp. subtilis str. 168, and B. lichiniformis (although these are not apparently the same two in each). One of these is designated as SigM in B. subtilis (Swiss_Prot:


Pssm-ID: 274361 [Multi-domain]  Cd Length: 154  Bit Score: 60.16  E-value: 1.94e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008   76 YAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHgrAKFSTWLYRVISNRCIDLRRKPRTENVDTVPEVADGRPDASRVI 155
Cdd:TIGR02950   9 FRYLYRLTKDKHLAEDLLQETFLKAYIHLHSFKD--SSIKPWLFRIARNAFIDWYRKDKKIQTIDDDAIGDLEQHPVESP 86
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499399008  156 ERNELNGMLEEA----MQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKRGRQQL 214
Cdd:TIGR02950  87 EHHLLIKIEQEEithhLSRLPENYRTVLILREFKEFSYKEIAELLNLSLAKVKSNLFRARKEL 149
PRK12546 PRK12546
RNA polymerase sigma factor; Provisional
74-210 3.60e-11

RNA polymerase sigma factor; Provisional


Pssm-ID: 139055 [Multi-domain]  Cd Length: 188  Bit Score: 60.24  E-value: 3.60e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  74 RAYAIALriVGNAADAEDVVQDSMLKIWSHRGRWQHGrAKFSTWLYRVISNRCIDLRRKPRTENVDTVPEVADG---RPD 150
Cdd:PRK12546  21 RAFAISL--TRNVAVADDLVQDTIVKAWTNFDKFQEG-TNLRAWLFTILRNTFYSDRRKHKREVPDPEGVHAASlavKPA 97
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 151 ASRVIERNELNgmleEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKRG 210
Cdd:PRK12546  98 HDGRLAMSDFR----AAFAQLPDEQREALILVGASGFSYEEAAEMCGVAVGTVKSRANRA 153
PRK09047 PRK09047
RNA polymerase factor sigma-70; Validated
83-197 3.91e-11

RNA polymerase factor sigma-70; Validated


Pssm-ID: 236367 [Multi-domain]  Cd Length: 161  Bit Score: 59.60  E-value: 3.91e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  83 VGNAADAEDVVQDSMLKIWSHRGrwQHGRAKFSTWLYRVISNRCIDLRRKPRTEN--------------------VDTVP 142
Cdd:PRK09047   1 VRDDDAALDIVQDAMIKLAEKYG--DRPAAEWPPLFQRILQNRIHDWFRRQKVRNtwvslfssfsdddddddfdpLETLD 78
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 499399008 143 EVADGRPDASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMD 197
Cdd:PRK09047  79 SADEGAESPADKLERAQVLQLIEEAIQKLPARQREAFLLRYWEDMDVAETAAAMG 133
PRK12543 PRK12543
RNA polymerase sigma factor; Provisional
60-210 6.70e-11

RNA polymerase sigma factor; Provisional


Pssm-ID: 183582 [Multi-domain]  Cd Length: 179  Bit Score: 59.36  E-value: 6.70e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  60 DETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGRAkFSTWLYRVISNRCIDLRRK------- 132
Cdd:PRK12543   5 DQEAFSEIYDVTIQEVYKTVHFLVEDKQDVDDVVNEIYIQLWESLRKYDSNRP-FRFWLIGLVIKQIHSWRRKrwrrfri 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 133 -------PRTENVDTVPEVADgrpdasrvierNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVES 205
Cdd:PRK12543  84 fekaeeqRKPVSIDFSEDVLS-----------KESNQELIELIHKLPYKLRQVIILRYLHDYSQEEIAQLLQIPIGTVKS 152

                 ....*
gi 499399008 206 LLKRG 210
Cdd:PRK12543 153 RIHAA 157
PRK12533 PRK12533
RNA polymerase sigma factor; Provisional
57-214 9.24e-11

RNA polymerase sigma factor; Provisional


Pssm-ID: 237129 [Multi-domain]  Cd Length: 216  Bit Score: 59.36  E-value: 9.24e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  57 AADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGRAKfsTWLYRVISNRCID--LRRKPR 134
Cdd:PRK12533  13 AAARGERFRQLVLPHLDAAYNLARWLCGNASDADDVVQEACMRALRFFDSFRGDNAR--PWLLAIVRHTWYSewRRRANA 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 135 TENV--------DTVPEVADGRPDASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESL 206
Cdd:PRK12533  91 HEVAapdtlddaDSLDDWQPAGEDPLALLLRAEDVRLVNAALAKLPVEYREVLVLRELEDMSYREIAAIADVPVGTVMSR 170

                 ....*...
gi 499399008 207 LKRGRQQL 214
Cdd:PRK12533 171 LARARRRL 178
PRK12511 PRK12511
RNA polymerase sigma factor; Provisional
74-210 2.14e-10

RNA polymerase sigma factor; Provisional


Pssm-ID: 237123 [Multi-domain]  Cd Length: 182  Bit Score: 57.87  E-value: 2.14e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  74 RAYAIALriVGNAADAEDVVQDSMLKIWSHRGRWQHGrAKFSTWLYRVISNRCIDLRRKPRTENV--DTVPEVADGRPDA 151
Cdd:PRK12511  18 RRYARSL--TRDSAEAEDLVHDALVRALERRASFRSG-GNLRTWLMSILHNAFIDELRRRRVEARraDELAVLADASLPA 94
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 499399008 152 SRviERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKRG 210
Cdd:PRK12511  95 AQ--EHAVRLAQIRDAFFDLPEEQRAALHLVAIEGLSYQEAAAVLGIPIGTLMSRIGRA 151
Sigma70_r4_2 pfam08281
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
163-210 2.31e-10

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif.


Pssm-ID: 400535 [Multi-domain]  Cd Length: 54  Bit Score: 54.38  E-value: 2.31e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 499399008  163 MLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKRG 210
Cdd:pfam08281   3 ALLRALEELPPRQREVFLLRYLEGLSYAEIAELLGISEGTVKSRLSRA 50
PRK09636 PRK09636
RNA polymerase sigma factor SigJ; Provisional
69-209 4.80e-10

RNA polymerase sigma factor SigJ; Provisional


Pssm-ID: 236600 [Multi-domain]  Cd Length: 293  Bit Score: 58.01  E-value: 4.80e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  69 ERHIDRAYAIALRIVGNAADAEDVVQDSMLkiwshrgRWQhgRAKFST------WLYRVISNRCID-LR--RKPRTENV- 138
Cdd:PRK09636  11 EPLRPHLLSVAYRMLGSVADAEDIVQEAWL-------RWN--NADRAQirdpraWLTRVVTRLCLDrLRsaRHRRETYVg 81
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499399008 139 ----DTVPEVADGRPDASRVIERNELNGMLeeAMQRLPEQQRIAVILsyHE--DMSNGEIAEVMDSTVAAVESLLKR 209
Cdd:PRK09636  82 pwlpEPVVEELDDPLEAVVAAEDLSLALML--ALERLSPLERAAFLL--HDvfGVPFDEIASTLGRSPAACRQLASR 154
PRK12526 PRK12526
RNA polymerase sigma factor; Provisional
48-208 2.35e-09

RNA polymerase sigma factor; Provisional


Pssm-ID: 237127 [Multi-domain]  Cd Length: 206  Bit Score: 55.19  E-value: 2.35e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  48 EDSELLDRLAAD-DETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGRAKFSTWLYRVISNRC 126
Cdd:PRK12526  23 ELSQWLILVAISrDKQAFTHLFQFFAPKIKRFGIKQLGNEAQANELVQETMSNVWRKAHLYNGDKGAATTWVYTVMRNAA 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 127 IDLRRKPRTENVDTVPEvaDGRPDASRVIERN----ELNGMLEEA-----MQRLPEQQRIAVILSYHEDMSNGEIAEVMD 197
Cdd:PRK12526 103 FDMLRKIKAKKEQNLGD--DIWPIEQALAESQseseEFSDHLMDKqilsyIEKLPEAQQTVVKGVYFQELSQEQLAQQLN 180
                        170
                 ....*....|.
gi 499399008 198 STVAAVESLLK 208
Cdd:PRK12526 181 VPLGTVKSRLR 191
Sig-70_gvs1 TIGR02989
RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family; This group of sigma ...
63-209 6.43e-09

RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family; This group of sigma factors are members of the sigma-70 family (TIGR02937) and are abundantly found in the species Rhodopirellula baltica (11), and Verrucomicrobium spinosum (16) and to a lesser extent in Gemmata obscuriglobus (2).


Pssm-ID: 274379 [Multi-domain]  Cd Length: 159  Bit Score: 53.09  E-value: 6.43e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008   63 AFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGrAKFSTWLYRVISNRCIDLRRKPRTENVDTVP 142
Cdd:TIGR02989   2 AFVRLLTRHERALRAFVRSLVADRDDVDDVLQETFVVAWRKFDQFDPG-TNFVAWARGIARNKVLNYRRKLGRDRLVFDD 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  143 EVADGRPDASRVIERNELNGM---LEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKR 209
Cdd:TIGR02989  81 DLLEALAAEAEPTEAERLSDDrqaLEGCLEKLPERQRELLDLRYQRGQKATALAEQTGRTVNAVYKALQR 150
CAS_III-E_sigma NF041236
type III-E CRISPR-associated RpoE-like sigma factor;
86-197 7.83e-09

type III-E CRISPR-associated RpoE-like sigma factor;


Pssm-ID: 469138 [Multi-domain]  Cd Length: 192  Bit Score: 53.54  E-value: 7.83e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  86 AADAEDVVQDSMLKIWSHRGRWQhGR--AKFSTWLYRVISNRCIDLRRKPRTENVDTVPEV---ADGRPDASRVIERNEL 160
Cdd:NF041236  47 PEDREDILSETVEAVQRGIGKFE-GRrgAKFSTWVWRIFRNKRVDYFRKKYKKKEYSLPLEgaeDDQEEEPEDDIEEMFA 125
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 499399008 161 NGMLEEAM-QRLPEQQR--IAVILSYHEDMSNG----EIAEVMD 197
Cdd:NF041236 126 AEDIIECLkKKVDDGETgcIRLLLDLYRWFKEGltqkEMAESYG 169
PRK09646 PRK09646
ECF RNA polymerase sigma factor SigK;
51-210 3.10e-08

ECF RNA polymerase sigma factor SigK;


Pssm-ID: 182015 [Multi-domain]  Cd Length: 194  Bit Score: 51.98  E-value: 3.10e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  51 ELLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGRAKFSTWLYRVISNRCIDLR 130
Cdd:PRK09646  19 ALLRRVARGDQDAFAELYDRTSSRVYGLVRRVLRDPGYSEETTQEVYLEVWRTASRFDPARGSALAWLLTLAHRRAVDRV 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 131 RKPRTEN--------------VDTVPEVADGRPDASRViernelngmlEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVM 196
Cdd:PRK09646  99 RSEQAASqrevrygarnvdpaFDQVAEEVEARLERERV----------RDCLDALTDTQRESVTLAYYGGLTYREVAERL 168
                        170
                 ....*....|....
gi 499399008 197 DSTVAAVESLLKRG 210
Cdd:PRK09646 169 AVPLGTVKTRMRDG 182
PRK12512 PRK12512
RNA polymerase sigma factor; Provisional
47-210 3.60e-08

RNA polymerase sigma factor; Provisional


Pssm-ID: 171551 [Multi-domain]  Cd Length: 184  Bit Score: 51.62  E-value: 3.60e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  47 DEDSELLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAA----DAEDVVQDSMLKIWSHRGRWQHGrAKFSTWLYRVI 122
Cdd:PRK12512   7 DEWTDLMRSANAGDAAAYRRLLKAVTPVLRAAARRGLARAGqpadQAEDIVQEILLAVHLKRHTWDPG-APFAPWLFAIA 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 123 SNRCID-LRRKPRTENVDtVPEVADGRP--DASRVIERNELNGMLEeamqRLPEQQRIAVILSYHEDMSNGEIAEVMDST 199
Cdd:PRK12512  86 RNKLIDaLRRRGRRVFVD-IDDFAETLPaePATETLPAGDVGRHLE----TLPPRQRDVVQSISVEGASIKETAAKLSMS 160
                        170
                 ....*....|.
gi 499399008 200 VAAVESLLKRG 210
Cdd:PRK12512 161 EGAVRVALHRG 171
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
163-210 7.07e-08

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 47.87  E-value: 7.07e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 499399008 163 MLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKRG 210
Cdd:cd06171    3 RLEEALDKLPEREREVILLRFGEGLSYEEIAEILGISRSTVRQRLHRA 50
PRK12527 PRK12527
RNA polymerase sigma factor; Reviewed
83-204 8.35e-08

RNA polymerase sigma factor; Reviewed


Pssm-ID: 171560 [Multi-domain]  Cd Length: 159  Bit Score: 50.16  E-value: 8.35e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  83 VGNAADAEDVVQDSMLKIW--SHRGRWQHGRAkfstWLYRVISNRCIDLRRKPRTENVDTVpEVADGR-----PDASRVI 155
Cdd:PRK12527  16 LGNRQAAEDVAHDAYLRVLerSSSAQIEHPRA----FLYRTALNLVVDRHRRHRVRQAEPL-EVLDEEerlhsPSPQTRL 90
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 499399008 156 ERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVE 204
Cdd:PRK12527  91 DLGQRLALLQRALAELPPACRDSFLLRKLEGLSHQQIAEHLGISRSLVE 139
PRK12516 PRK12516
RNA polymerase sigma factor; Provisional
74-209 1.06e-07

RNA polymerase sigma factor; Provisional


Pssm-ID: 183568 [Multi-domain]  Cd Length: 187  Bit Score: 50.35  E-value: 1.06e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  74 RAYAIALriVGNAADAEDVVQDSMLKIWSHRGRWQHGrAKFSTWLYRVISNRCIDLRRKPRTENVDTvpevaDGRPDASR 153
Cdd:PRK12516  24 RAFAVSL--IGRHDRADDLVQDTIMKAWAKQDHFEVG-TNMKAWLFTILRNEFYSQMRKRGREVQDT-----DGMFTEQL 95
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 154 VIERNELNGM----LEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKR 209
Cdd:PRK12516  96 AVHPSQYGTLdlqdFRAALDQLPDDQREAIILVGASGFAYEEAAEICGCAVGTIKSRVNR 155
PRK12547 PRK12547
RNA polymerase sigma factor; Provisional
74-209 1.41e-07

RNA polymerase sigma factor; Provisional


Pssm-ID: 139056 [Multi-domain]  Cd Length: 164  Bit Score: 49.49  E-value: 1.41e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  74 RAYAIALriVGNAADAEDVVQDSMLKIWSHRGRWQHGrAKFSTWLYRVISNRCIDLRRKPRTENVDTvpevaDGRPdASR 153
Cdd:PRK12547  20 RAFAVSL--SSKHDKAEDLVQDTLMKAWAKQDSFEMG-TNLKAWLFTILRNEFYSQMRKRGREVQDS-----DGVF-TAR 90
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499399008 154 VIERNELNGMLE-----EAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKR 209
Cdd:PRK12547  91 VAVHPAQYGSLDlqdfkKALNLLSADQREAIILIGASGFSYEDAAAICGCAVGTIKSRVSR 151
PRK09644 PRK09644
RNA polymerase sigma factor SigM; Provisional
89-214 6.98e-07

RNA polymerase sigma factor SigM; Provisional


Pssm-ID: 170033 [Multi-domain]  Cd Length: 165  Bit Score: 47.57  E-value: 6.98e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  89 AEDVVQDSMLKIWSHRGRWQHGRAKfsTWLYRVISNRCIDLRRKPRTENVDTVPEVADGRPDASR-VIERNELNGMLEEA 167
Cdd:PRK09644  28 AEDLLQETFYRAYIYLEDYDNQKVK--PWLFKVAYHTFIDFVRKEKKVSFVGTDEIEAIQAESTEeYVVAKNSYEKLIQI 105
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 499399008 168 MQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKRGRQQL 214
Cdd:PRK09644 106 IHTLPVIEAQAILLCDVHELTYEEAASVLDLKLNTYKSHLFRGRKRL 152
PRK06288 PRK06288
RNA polymerase sigma factor WhiG; Reviewed
138-199 1.09e-06

RNA polymerase sigma factor WhiG; Reviewed


Pssm-ID: 235770 [Multi-domain]  Cd Length: 268  Bit Score: 48.14  E-value: 1.09e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 499399008 138 VDTVPEVADGRPDAsrVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDST 199
Cdd:PRK06288 182 MDTLESPAALNPDE--IAEREEIKRVIVEAIKTLPEREKKVLILYYYEDLTLKEIGKVLGVT 241
PRK12545 PRK12545
RNA polymerase factor sigma-70;
57-147 1.16e-06

RNA polymerase factor sigma-70;


Pssm-ID: 183584 [Multi-domain]  Cd Length: 201  Bit Score: 47.64  E-value: 1.16e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  57 AADDETAFRMLVERHIDRAYAIALRivgNAADAEDVVQDSMLKIWSHRGRWQhGRAKFSTWLYRVISNRCID-LRRKPRT 135
Cdd:PRK12545   6 SAHDDPAYLAQLRHDLLRFARLQLR---DADAAEDAVQEALAAAWSQAGRFA-GQSAHKTWVFGILRNKLIDtLRARQRT 81
                         90
                 ....*....|..
gi 499399008 136 ENVDTVPEVADG 147
Cdd:PRK12545  82 VNLSALDAELDG 93
PRK09639 PRK09639
RNA polymerase sigma factor SigX; Provisional
59-210 1.69e-06

RNA polymerase sigma factor SigX; Provisional


Pssm-ID: 236602 [Multi-domain]  Cd Length: 166  Bit Score: 46.48  E-value: 1.69e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  59 DDETaFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWshRGRWqHGRAKFSTWLYRVISNRCIDL-----RRKP 133
Cdd:PRK09639   1 SDET-FEDLFEQYYPDVVQQIFYIVKDRTQAEDLAQEVFLRLY--RSDF-KGIENEKGWLIKSARNVAYNYlrsekRRRA 76
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499399008 134 RTENVDTVPEVaDGRPDASRVIERNELNGMLEEAMQRLPEQQRiAVILSYHEDMSNGEIAEVMDSTVAAVESLLKRG 210
Cdd:PRK09639  77 RILGEFQWQEV-DNEPSPEEIWIRKEEITKVQEVLAKMTERDR-TVLLLRFSGYSYKEIAEALGIKESSVGTTLARA 151
PRK13919 PRK13919
putative RNA polymerase sigma E protein; Provisional
49-209 2.32e-06

putative RNA polymerase sigma E protein; Provisional


Pssm-ID: 184395 [Multi-domain]  Cd Length: 186  Bit Score: 46.45  E-value: 2.32e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  49 DSELLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGRAKFSTWLYRVISNRCID 128
Cdd:PRK13919  10 DEALLALVARGEEEALRALFRRYAGAFLALARRMGLDGAAAEDVVQEVFIRVWKKAKEFDPRRGSARAWLLALAHHAAVD 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 129 -LRR---KPRTENVDTVPEVADGRPDASRVIERNELNGMLEEAMQRL-PEQQRIAVILsYHEDMSNGEIAEVMDSTVAAV 203
Cdd:PRK13919  90 hVRRraaRPQPLEPDEREPEAFDLPGPGLDEEGHLDRTRLGRALKALsPEERRVIEVL-YYQGYTHREAAQLLGLPLGTL 168

                 ....*.
gi 499399008 204 ESLLKR 209
Cdd:PRK13919 169 KTRARR 174
PRK09642 PRK09642
RNA polymerase sigma factor;
76-210 4.12e-06

RNA polymerase sigma factor;


Pssm-ID: 170031 [Multi-domain]  Cd Length: 160  Bit Score: 45.48  E-value: 4.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  76 YAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGRAKfsTWLYRVISNRCIDLRRKPRTENVD-TVPEVADGRPDASRV 154
Cdd:PRK09642   9 FQVIFSILRHEEDAKDVTQEVFVKIHASLPNYQFRGLK--TWMARIATNHAIDYKRKKARENEElSLCKETEENIKSSHN 86
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 155 IE----RNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKRG 210
Cdd:PRK09642  87 IEdlllTKEQKLLIAQKLRELPENYRDVVLAHYLEEKSYQEIALQEKIEVKTVEMKLYRA 146
PRK09648 PRK09648
RNA polymerase sigma factor ShbA;
48-203 4.20e-06

RNA polymerase sigma factor ShbA;


Pssm-ID: 236607 [Multi-domain]  Cd Length: 189  Bit Score: 45.73  E-value: 4.20e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  48 EDSELLDRL----AADDETAFRMLVE--RHIDRAYAIAL--RIVGNAADAEDVVQDSMLKIWSHRGRWQHGRAKFSTWLY 119
Cdd:PRK09648   6 DTGEELDALvaeaVAGDRRALREVLEiiRPLVVRYCRARlgGVERPGLSADDVAQEVCLAVITALPRYRDQGRPFLAFVY 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 120 RVISNRCIDLRR---KPRTENVDTVPEVADGRPDASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVM 196
Cdd:PRK09648  86 GIAAHKVADAHRaagRDKAVPTEEVPERPSDDAGPEERALRSESSNRMRELLDTLPEKQREILILRVVVGLSAEETAEAV 165

                 ....*..
gi 499399008 197 DSTVAAV 203
Cdd:PRK09648 166 GSTPGAV 172
PRK12540 PRK12540
RNA polymerase sigma factor; Provisional
74-209 4.71e-06

RNA polymerase sigma factor; Provisional


Pssm-ID: 183579 [Multi-domain]  Cd Length: 182  Bit Score: 45.73  E-value: 4.71e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  74 RAYAIALRivGNAADAEDVVQDSMLKIWSHRGRWQHGrAKFSTWLYRVISNRCIDLRRKPRTENVDTVPEVA---DGRPD 150
Cdd:PRK12540  19 RAFAISLS--GNGDRADDLVQETLLRALANIDSFQPG-SNLPAWLFTILRNLFRSDYRKRRREVEDADGSYAktlKSQPG 95
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 499399008 151 ASRVIERNELNGMLEeamqRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKR 209
Cdd:PRK12540  96 QNAHLEFEEFRAALD----KLPQDQREALILVGASGFSYEDAAAICGCAVGTIKSRVNR 150
PRK12532 PRK12532
RNA polymerase sigma factor; Provisional
80-209 5.99e-06

RNA polymerase sigma factor; Provisional


Pssm-ID: 171564 [Multi-domain]  Cd Length: 195  Bit Score: 45.31  E-value: 5.99e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  80 LRIVGNAADAEDVVQDSMLKIWSHRGRWQhGRAKFSTWLYRVISNRCID-LRRKPRT---------ENVDTVPEV----- 144
Cdd:PRK12532  24 LQLPDHPDLAEDLVQETLLSAYSAGDSFQ-GRALVNSWLFAILKNKIIDaLRQIGRQrkvftllddELLDEAFEShfsqn 102
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499399008 145 ----ADGRP----DASRVIERNELNGMLEEAMQRLPEQqrIAVILSYHE--DMSNGEIAEVMDSTVAAVESLLKR 209
Cdd:PRK12532 103 ghwtPEGQPqhwnTPEKSLNNNEFQKILQSCLYNLPEN--TARVFTLKEilGFSSDEIQQMCGISTSNYHTIMHR 175
sigI PRK09635
RNA polymerase sigma factor SigI; Provisional
74-209 7.77e-06

RNA polymerase sigma factor SigI; Provisional


Pssm-ID: 182008 [Multi-domain]  Cd Length: 290  Bit Score: 45.73  E-value: 7.77e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  74 RAYAI--ALRIVGNAADAEDVVQDSMLKIW-SHRGRWQHGRAkfstWLYRVISNRCIDLRRKPRT--ENVDTVPEVADGR 148
Cdd:PRK09635  15 RAYLVdlAFRMVGDIGVAEDMVQEAFSRLLrAPVGDIDDERG----WLIVVTSRLCLDHIKSASTrrERPQDIAAWHDGD 90
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499399008 149 PD------ASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKR 209
Cdd:PRK09635  91 ASvssvdpADRVTLDDEVRLALLIMLERLGPAERVVFVLHEIFGLPYQQIATTIGSQASTCRQLAHR 157
PRK06811 PRK06811
RNA polymerase factor sigma-70; Validated
45-211 1.91e-05

RNA polymerase factor sigma-70; Validated


Pssm-ID: 180707 [Multi-domain]  Cd Length: 189  Bit Score: 43.77  E-value: 1.91e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  45 VFDEDSELLDRLAADDETAFRMLVERHIDRAYAIALRIVGNAA---DAEDVVQDSMLKIWSHRGRWQHGRAKFSTWLYRV 121
Cdd:PRK06811   1 MKINEDNFIKELKKKNEKALEFIVDTYGNLVKKIVHKVLGTVNysqLIEECVNDIFLSIWNNIDKFDEEKGSFKKWIAAI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 122 ISNRCIDLRRKPRTE-NVDTVPEVADGRPDA--SRVIERNELNGMLEeAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDS 198
Cdd:PRK06811  81 SKYKAIDYKRKLTKNnEIDSIDEFILISEESieNEIILKENKEEILK-LINDLEKLDREIFIRRYLLGEKIEEIAKKLGL 159
                        170
                 ....*....|...
gi 499399008 199 TVAAVESLLKRGR 211
Cdd:PRK06811 160 TRSAIDNRLSRGR 172
FliA COG1191
DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA ...
149-209 2.09e-05

DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA polymerase specialized sigma subunit is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 440804 [Multi-domain]  Cd Length: 236  Bit Score: 44.04  E-value: 2.09e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499399008 149 PDASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKR 209
Cdd:COG1191  165 GDPEEELEHEELREALAEAIEQLPERERLVLSLYYFEELTLKEIAEVLGVSESRVSRLHKK 225
PRK07037 PRK07037
extracytoplasmic-function sigma-70 factor; Validated
78-178 4.55e-05

extracytoplasmic-function sigma-70 factor; Validated


Pssm-ID: 180803 [Multi-domain]  Cd Length: 163  Bit Score: 42.36  E-value: 4.55e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  78 IALRIVGNAADAEDVVQDSMLKIWSHRGRwQHGRAKFStWLYRVISNRCIDLRRKPRTENVDTVPE-------VADGRPD 150
Cdd:PRK07037  14 IAARIVGCRSRAEDVVQDAFVKLVEAPNQ-DAVKQPVA-YLFRIVRNLAIDHYRRQALENKYHGDEedgldvpSPEASPE 91
                         90       100
                 ....*....|....*....|....*...
gi 499399008 151 ASrVIERNELNgMLEEAMQRLPEQQRIA 178
Cdd:PRK07037  92 AA-LINRDTLR-HVADALSELPARTRYA 117
PRK12530 PRK12530
RNA polymerase sigma factor; Provisional
85-209 6.06e-05

RNA polymerase sigma factor; Provisional


Pssm-ID: 237128 [Multi-domain]  Cd Length: 189  Bit Score: 42.45  E-value: 6.06e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  85 NAADAEDVVQDSMLKIWSHRGRWQhGRAKFSTWLYRVISNRCIDL-RRKPRTENVDTVPEVAD--------GRPDASRvI 155
Cdd:PRK12530  30 DADLAEDVVQEALVSAYKNADSFK-GQSALKTWIFAILKNKIIDLiRYRKRFVNESELIEEDSpnsffdekGHWKPEY-Y 107
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499399008 156 ERNELNG------------MLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKR 209
Cdd:PRK12530 108 EPSEWQEventvykeefwlIFEACLNHLPAQQARVFMMREYLELSSEQICQECDISTSNLHVLLYR 173
Sigma70_r4 pfam04545
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
167-210 1.11e-04

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif. Due to the way Pfam works, the threshold has been set artificially high to prevent overlaps with other helix-turn-helix families. Therefore there are many false negatives.


Pssm-ID: 461347 [Multi-domain]  Cd Length: 50  Bit Score: 38.56  E-value: 1.11e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 499399008  167 AMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKRG 210
Cdd:pfam04545   1 ALASLPPRERQVLVLRYGEGLTLEEIGERLGISRERVRQIEKRA 44
PRK12541 PRK12541
RNA polymerase sigma factor; Provisional
63-212 1.25e-04

RNA polymerase sigma factor; Provisional


Pssm-ID: 183580 [Multi-domain]  Cd Length: 161  Bit Score: 41.08  E-value: 1.25e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  63 AFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGRAKfsTWLYRVISNRCIDLRRKPRTENVDTVP 142
Cdd:PRK12541   6 SLEEIYSEHMQDLFRYLLSLTGDSHFAEDLMQETFYRMLVHIDYYKGEEIR--PWLFTIAYNAFIDWYRKEKKYKTTTIE 83
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 499399008 143 EVA-DGRPDAS-RVIERNELNGMLEEAMQRLPEQQRIAVILSYHeDMSNGEIAEVMDSTVAAVESLLKRGRQ 212
Cdd:PRK12541  84 EFHlPNVPSTEhEYFIKHEIASWLDSLSSLPLERRNVLLLRDYY-GFSYKEIAEMTGLSLAKVKIELHRGRK 154
PRK12536 PRK12536
RNA polymerase sigma factor; Provisional
52-210 1.33e-04

RNA polymerase sigma factor; Provisional


Pssm-ID: 237131 [Multi-domain]  Cd Length: 181  Bit Score: 41.19  E-value: 1.33e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  52 LLDRLAADDETAFRMLVE---RHIdRAYaIALRIVGNAADAEDVVQDSMLKIWSHRGRWQHGrAKFSTWLYRVISNRCID 128
Cdd:PRK12536  11 LLLRGLAGDAAAYRQFLSelaAHL-RGF-LRRRLPQLPDEVEDLVQEILLAVHNARHTYRAD-QPLTAWVHAIARYKLMD 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 129 -LRRKPRTENV-DTVPEVAD--GRPDASRVIERNELNGMLEEamqrLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVE 204
Cdd:PRK12536  88 fLRSRARREALhDPLDDESElfATSDDEAAEARRDLGKLLEQ----LPDRQRLPIVHVKLEGLSVAETAQLTGLSESAVK 163

                 ....*.
gi 499399008 205 SLLKRG 210
Cdd:PRK12536 164 VGIHRG 169
PRK12544 PRK12544
RNA polymerase factor sigma-70;
83-209 1.53e-04

RNA polymerase factor sigma-70;


Pssm-ID: 183583 [Multi-domain]  Cd Length: 206  Bit Score: 41.33  E-value: 1.53e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  83 VGNAADAEDVVQDSMLKIWSHRGRWQhGRAKFSTWLYRVISNRCID-LRRKPRTENVDTVPEVADGRPDASRVIERN--- 158
Cdd:PRK12544  39 LSDLHLAEDAVQEALIGALKNADSFA-GRAAFKTWVFAILKNKIIDlLRQKKRHVSASSLLRDEEEEEDFEELFDESghw 117
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 159 ----------ELNGMLEEA---------MQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKR 209
Cdd:PRK12544 118 qkderpqawgNPEESLEQEqfwrifeacLDGLPAKYARVFMMREFIELETNEICHAVDLSVSNLNVLLYR 187
fliA PRK06986
flagellar biosynthesis sigma factor; Validated
150-209 4.95e-04

flagellar biosynthesis sigma factor; Validated


Pssm-ID: 235901 [Multi-domain]  Cd Length: 236  Bit Score: 40.22  E-value: 4.95e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 150 DASRVIERNELNGMLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLKR 209
Cdd:PRK06986 164 DPLQQLEDEELREALVEAIESLPEREQLVLSLYYQEELNLKEIGAVLGVSESRVSQIHSQ 223
PRK12539 PRK12539
RNA polymerase sigma factor SigF;
60-210 1.10e-03

RNA polymerase sigma factor SigF;


Pssm-ID: 237132 [Multi-domain]  Cd Length: 184  Bit Score: 38.56  E-value: 1.10e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  60 DETAFRMLVER---HIDRAYAIALRIVGNAAD-AEDVVQDSMLKIWSHRGRWQhGRAKFSTWLYRVISNRCID-LRRKPR 134
Cdd:PRK12539  19 DAAAHRALLERlsgHLRAYYKGKLARIGRGAEeAEDLVQEALMAIHTRRHTYD-PEQPLTPWVYAIARYKLIDhLRRTRA 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 135 T------ENVDTVPEvADGRPDASRVIErnelngmLEEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLK 208
Cdd:PRK12539  98 SladvpiDDADELVA-HDDHAAVESTLD-------LGRLLARLPEKMRLAIQAVKLEGLSVAEAATRSGMSESAVKVSVH 169

                 ..
gi 499399008 209 RG 210
Cdd:PRK12539 170 RG 171
PRK12542 PRK12542
RNA polymerase sigma factor; Provisional
55-210 4.07e-03

RNA polymerase sigma factor; Provisional


Pssm-ID: 183581 [Multi-domain]  Cd Length: 185  Bit Score: 36.95  E-value: 4.07e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008  55 RLAADDETAFRMLVERHIDRAYAIALRIVGNAADAEDVVQDSMLKIWSHRGRWQH-GRAKFSTWLYRVISNRCIDLRRKP 133
Cdd:PRK12542   2 KVTNNDYEKMEELYELYEQKVYYVAYSILNNIQQAEDAVQETFITLYKNLEKLHSlNTQELKRYILRVAKNKAIDSYRKN 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499399008 134 R----------TENVDTVPEVADGRpdASRVIERNELNGMLEEamqrLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAV 203
Cdd:PRK12542  82 KrhetfleeyeRESIEAVDENIEEW--EKRKMSEVQIDTLLKE----LNESNRQVFKYKVFYNLTYQEISSVMGITEANV 155

                 ....*..
gi 499399008 204 ESLLKRG 210
Cdd:PRK12542 156 RKQFERA 162
PRK09191 PRK09191
two-component response regulator; Provisional
165-208 9.17e-03

two-component response regulator; Provisional


Pssm-ID: 236402 [Multi-domain]  Cd Length: 261  Bit Score: 36.36  E-value: 9.17e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 499399008 165 EEAMQRLPEQQRIAVILSYHEDMSNGEIAEVMDSTVAAVESLLK 208
Cdd:PRK09191  83 ERRLAGLTPLPRQAFLLTALEGFSVEEAAEILGVDPAEAEALLD 126
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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