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Conserved domains on  [gi|499225284|ref|WP_010922824|]
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MULTISPECIES: iron ABC transporter permease [Staphylococcus]

Protein Classification

FecCD family ABC transporter permease( domain architecture ID 10001816)

FecCD family ABC transporter permease such as iron ABC transporter permease, which is the transmembrane subunit (TM) found in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter involved in the import of iron and iron-containing compounds

CATH:  1.10.3470.10
Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
SCOP:  4002900
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 26-311 4.86e-60

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


:

Pssm-ID: 440374  Cd Length: 306  Bit Score: 194.13  E-value: 4.86e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284  26 LGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFG--SGLALFLGLTTLWIPVF 103
Cdd:COG0609   19 LGPDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGavLAIVLGGGLSALGLPLA 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 104 SITFSLITLITVLVITSVLSQGYPVRiLILSGLMIGALFNSLLYFLILL-KPRKLNTIANYLFGGFGDAEYSNVSIIAIT 182
Cdd:COG0609   99 AFLGALLAALLVYLLARRGGGLSPLR-LVLAGVAVSALFSALTSLLLLLaDPEQLRSIVFWLMGSLAGASWDDVLLLLPV 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 183 FIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWqWKQSLGRQ 262
Cdd:COG0609  178 LLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGLVVPHIARLL-VGPDHRRL 256

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 499225284 263 LALNIVIGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQ 311
Cdd:COG0609  257 LPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRR 305
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 26-311 4.86e-60

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 194.13  E-value: 4.86e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284  26 LGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFG--SGLALFLGLTTLWIPVF 103
Cdd:COG0609   19 LGPDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGavLAIVLGGGLSALGLPLA 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 104 SITFSLITLITVLVITSVLSQGYPVRiLILSGLMIGALFNSLLYFLILL-KPRKLNTIANYLFGGFGDAEYSNVSIIAIT 182
Cdd:COG0609   99 AFLGALLAALLVYLLARRGGGLSPLR-LVLAGVAVSALFSALTSLLLLLaDPEQLRSIVFWLMGSLAGASWDDVLLLLPV 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 183 FIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWqWKQSLGRQ 262
Cdd:COG0609  178 LLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGLVVPHIARLL-VGPDHRRL 256

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 499225284 263 LALNIVIGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQ 311
Cdd:COG0609  257 LPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRR 305
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 26-309 1.63e-46

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 159.23  E-value: 1.63e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284   26 LGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGS--GLALFLGLTTLWIPVF 103
Cdd:pfam01032  26 LLGGDDSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISSGAALGAvlAILLGGSLSLFALPLA 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284  104 SITFSLITLITVLVITSVLSQGYPVRiLILSGLMIGALFNSLLYFLILLK-PRKLNTIANYLFGGFGDAEYSNVSIIAIT 182
Cdd:pfam01032 106 AFIGALLAALLVYFLSRGRGGASPLR-LILAGIAVSALLSALTSLLLLLLnPEALQSILFWLMGSLSGANWSDVLILLPL 184

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284  183 FIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQwKQSLGRQ 262
Cdd:pfam01032 185 LLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPIGFVGLIVPHIARLLV-GANHRRL 263

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 499225284  263 LALNIVIGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLI 309
Cdd:pfam01032 264 LPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLL 310
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
6-314 4.87e-35

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 134.20  E-value: 4.87e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284   6 VLLSWIVILIITTSIYLFwqLGDINDVFN------QSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGL 79
Cdd:PRK10577 357 WLLALGLLLLLALVVALS--FGRDAHGWNwlsgqlLDALLPLRLPRLLAALLAGAMLAVAGTLLQRLTRNPLASPEVLGI 434

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284  80 ASGATFGSGLALFL--GLTTLWIPVFSITFSLITLITVLVITSvlSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKL 157
Cdd:PRK10577 435 SSGAGLGVVLALFLvpGAGFGWLLAAALLGALAALALILLLAR--RGGFAPERLLLTGIALSALFTALIQLLLASGDPRA 512

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 158 NTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVG 237
Cdd:PRK10577 513 AQLLTWLSGSTYGVTWAQALPLLIVAVLLLALALLLRRWLDLLPLGDDTARALGLPVTRARLALLLLAALLTAAATATVG 592

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 238 IIGFIGMVIPQLIRkwqwkqSLG-----RQLALNIVIGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQS 312
Cdd:PRK10577 593 PLSFVGLMAPHLAR------MLGgrrarPQLVLAALLGALLMVLADWLGRTLLFPYQIPAGLLAALIGAPYFLWLLRRSR 666


                 ..
gi 499225284 313 KR 314
Cdd:PRK10577 667 RR 668
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 46-308 1.03e-31

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 118.81  E-value: 1.03e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284  46 LLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLWIPVFSITFSLITLITVLVITSVLSQG 125
Cdd:cd06550    1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAFAFAGALAIALLVLLLASRGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 126 YPVRILILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGEL 205
Cdd:cd06550   81 LSPSKLILIGIVLSAFFSAGVILISLLSDDSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFDED 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 206 KSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKwQWKQSLGRQLALNIVIGGQIMVMADFIGSHIL 285
Cdd:cd06550  161 LAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARR-LFGRSHRYLLPLSALLGAILLLLGDLLSRTLL 239

                        250       260
                 ....*....|....*....|...
gi 499225284 286 sPVQIPASIIIALIGIPVLFYML 308
Cdd:cd06550  240 -PSELPVGPVTALLGAPYFLYLL 261
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 26-311 4.86e-60

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 194.13  E-value: 4.86e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284  26 LGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFG--SGLALFLGLTTLWIPVF 103
Cdd:COG0609   19 LGPDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGavLAIVLGGGLSALGLPLA 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 104 SITFSLITLITVLVITSVLSQGYPVRiLILSGLMIGALFNSLLYFLILL-KPRKLNTIANYLFGGFGDAEYSNVSIIAIT 182
Cdd:COG0609   99 AFLGALLAALLVYLLARRGGGLSPLR-LVLAGVAVSALFSALTSLLLLLaDPEQLRSIVFWLMGSLAGASWDDVLLLLPV 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 183 FIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWqWKQSLGRQ 262
Cdd:COG0609  178 LLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGLVVPHIARLL-VGPDHRRL 256

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 499225284 263 LALNIVIGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQ 311
Cdd:COG0609  257 LPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRR 305
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 26-309 1.63e-46

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 159.23  E-value: 1.63e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284   26 LGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGS--GLALFLGLTTLWIPVF 103
Cdd:pfam01032  26 LLGGDDSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISSGAALGAvlAILLGGSLSLFALPLA 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284  104 SITFSLITLITVLVITSVLSQGYPVRiLILSGLMIGALFNSLLYFLILLK-PRKLNTIANYLFGGFGDAEYSNVSIIAIT 182
Cdd:pfam01032 106 AFIGALLAALLVYFLSRGRGGASPLR-LILAGIAVSALLSALTSLLLLLLnPEALQSILFWLMGSLSGANWSDVLILLPL 184

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284  183 FIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQwKQSLGRQ 262
Cdd:pfam01032 185 LLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPIGFVGLIVPHIARLLV-GANHRRL 263

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 499225284  263 LALNIVIGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLI 309
Cdd:pfam01032 264 LPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLL 310
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
6-314 4.87e-35

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 134.20  E-value: 4.87e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284   6 VLLSWIVILIITTSIYLFwqLGDINDVFN------QSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGL 79
Cdd:PRK10577 357 WLLALGLLLLLALVVALS--FGRDAHGWNwlsgqlLDALLPLRLPRLLAALLAGAMLAVAGTLLQRLTRNPLASPEVLGI 434

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284  80 ASGATFGSGLALFL--GLTTLWIPVFSITFSLITLITVLVITSvlSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKL 157
Cdd:PRK10577 435 SSGAGLGVVLALFLvpGAGFGWLLAAALLGALAALALILLLAR--RGGFAPERLLLTGIALSALFTALIQLLLASGDPRA 512

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 158 NTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVG 237
Cdd:PRK10577 513 AQLLTWLSGSTYGVTWAQALPLLIVAVLLLALALLLRRWLDLLPLGDDTARALGLPVTRARLALLLLAALLTAAATATVG 592

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 238 IIGFIGMVIPQLIRkwqwkqSLG-----RQLALNIVIGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQS 312
Cdd:PRK10577 593 PLSFVGLMAPHLAR------MLGgrrarPQLVLAALLGALLMVLADWLGRTLLFPYQIPAGLLAALIGAPYFLWLLRRSR 666


                 ..
gi 499225284 313 KR 314
Cdd:PRK10577 667 RR 668
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 46-308 1.03e-31

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 118.81  E-value: 1.03e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284  46 LLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLWIPVFSITFSLITLITVLVITSVLSQG 125
Cdd:cd06550    1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAFAFAGALAIALLVLLLASRGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 126 YPVRILILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGEL 205
Cdd:cd06550   81 LSPSKLILIGIVLSAFFSAGVILISLLSDDSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFDED 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 206 KSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKwQWKQSLGRQLALNIVIGGQIMVMADFIGSHIL 285
Cdd:cd06550  161 LAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARR-LFGRSHRYLLPLSALLGAILLLLGDLLSRTLL 239

                        250       260
                 ....*....|....*....|...
gi 499225284 286 sPVQIPASIIIALIGIPVLFYML 308
Cdd:cd06550  240 -PSELPVGPVTALLGAPYFLYLL 261
FepG COG4779
ABC-type enterobactin transport system, permease component [Inorganic ion transport and ...
 37-314 4.43e-30

ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443810  Cd Length: 344  Bit Score: 116.37  E-value: 4.43e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284  37 ILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLA-LFLGLTTLWIPVFSITFSLITLITV 115
Cdd:COG4779   68 VVLELRLPRALAALLVGAALGLSGAIFQSLTRNPLASPDIIGITAGASAGAVAAiVVLGGSGLAVALGALAGGLATALLV 147

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 116 LVIT-SVLSQGYpvRiLILSGLMIGALFNSLLYFLILLKP-RKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFII 193
Cdd:COG4779  148 YLLAwRGGVSGY--R-LILVGIGVSAMLTAVNSYLLTRADlEDAQSAAVWLTGSLNGRTWEDVLPLAVALAVLLPLALAL 224

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 194 LNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKwqwkqsLGRQLALNIV----I 269
Cdd:COG4779  225 ARRLRLLELGDDTAAALGVRVERTRLLLLLVAVALAAVATAAAGPIAFVALAAPQIARR------LTRSPGPPLLpsalV 298

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 499225284 270 GGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKR 314
Cdd:COG4779  299 GALLLLAADLVAQHLLAPVQLPVGVVTGALGGPYLLWLLIRENRR 343
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
31-308 6.31e-28

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 113.78  E-value: 6.31e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284  31 DVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFG--SGLALFLGLTTLWIPVFSITFS 108
Cdd:PRK10577  51 DDLEQLLLHYSRLPRLAIALLVGAALGLAGALLQQVLRNPLASPTTLGVAAGAQLAlvLATLFAPALLALASQLAAFAGG 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 109 LITLITVLVItSVLSQGYPVRiLILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALF 188
Cdd:PRK10577 131 LLAAALVFAL-AGGKRLSPLR-LVLAGMVVSLYLGALTTLLLLFNEQYLQGLFLWGAGSLAQNDWSGVQRLLPRLLVGLL 208

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 189 GIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQsLGRQLALNIV 268
Cdd:PRK10577 209 LLLLLARPLTLLGLGDDVARSLGLAVSLTRLAALALAVLLSAAVVSAVGPIGFIGLAAPNLARLLGARR-LRARLPLSPL 287

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 499225284 269 IGGQIMVMADFIGSHI--LSPVQIPASIIIALIGIPVLFYML 308
Cdd:PRK10577 288 IGALLLLLTDQLVRLLagVGGELLPTGAVTALIGAPLLLWLL 329
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
24-309 3.33e-26

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 105.51  E-value: 3.33e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284  24 WQLGDINDVfnqsILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGS--GLALFLGLTTLWIP 101
Cdd:PRK09777  37 WQAGDEHYY----VLMEYRLPRLLLALFVGAALAVSGVLVQGIVRNPLASPDILGVNHAASLASvgALLLFPSLPVMWLP 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 102 VFSITFSLITLITVLVITSvlsQGYPVRiLILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAI 181
Cdd:PRK09777 113 LLAFIGGMAGLILLKMLAG---THQPMK-LALTGVALSALWASLTDYLMLSRPQDINNALLWLTGSLWGRDWSFVKVALP 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 182 TFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWkqslGR 261
Cdd:PRK09777 189 WLILLLPLSLSFCRDLDLLALGDARATTLGVSVPHTQFWALLLAVALTATGVAACGPISFIGLVVPHLMRSLVG----GR 264

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 499225284 262 Q---LALNIVIGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLI 309
Cdd:PRK09777 265 HrrlLPVSALTGALLLLLADLLARIIHPPLELPAGVLTAIIGAPWFFWLLV 315
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
35-303 3.99e-26

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 105.55  E-value: 3.99e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284  35 QSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFgsGLALFLGLTTLWIPVFSITF-----SL 109
Cdd:PRK11228  44 EALVQNLRLPRSLVAVLIGASLALAGALLQTLTHNPLASPSLLGINSGAAL--AMALTSALSPTPFAGYSLAFiaacgGG 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 110 ITLITVLVITSVLSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFG 189
Cdd:PRK11228 122 LSWLLVMTAGGGWRHTHDRNRLILAGIALSALCMALTRITLLLAEDHAYGIFYWLAGGVSHARWQEVWQLLPFVVTAVPV 201

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 190 IFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQwKQSLGRQLALNIVI 269
Cdd:PRK11228 202 VLLLANQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLLVGACVSVAGPVAFIGLLVPHLARFWI-GYDQRNVLPMSMLL 280

                        250       260       270
                 ....*....|....*....|....*....|....
gi 499225284 270 GGQIMVMADFIGSHILSPVQIPASIIIALIGIPV 303
Cdd:PRK11228 281 GATLMLLADLLARALAFPGELPAGAVLALIGAPC 314
btuC PRK09535
cobalamin ABC transporter permease BtuC;
35-308 2.27e-24

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 101.37  E-value: 2.27e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284  35 QSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLT-TLWIPVFSITFSLITLI 113
Cdd:PRK09535  88 QTIVLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIGVSSGAAVGAVAAIVLPLAvPFGLQAAAFAGALVAAF 167

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 114 TVLVITSVLSQGyPVRILILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFII 193
Cdd:PRK09535 168 GVYAIATENGRT-PVATLLLAGVAVQTFLGAVISYLLLHSGESLRRAVYWLMGHLHGSTWSDVEVALPVVVVGFVVLLAY 246

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 194 LNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRkwqwkQSLGRQ----LALNIVI 269
Cdd:PRK09535 247 ARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAGVIGFVGLIVPHVMR-----LLVGPDhrilLPTSALA 321

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 499225284 270 GGQIMVMADFIGShiLSPVQIPASIIIALIGIPVLFYML 308
Cdd:PRK09535 322 GASFLVATDTVAR--SGPAEVPVGIVTAALGAPFFLYLL 358
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 33-309 3.10e-18

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 83.47  E-value: 3.10e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284  33 FNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLwiPVFSITFSLIT- 111
Cdd:PRK03784  49 RGELFVWQLRLPRTLAVLLVGAALAVSGAVMQALFENPLAEPGLLGVSNGAGVALVAAVLLGQGLL--PPWALSLCAIAg 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 112 --LITVLVITSVLSQGYPVRILILSGLMIGALFNSL----LYFLILLKPRKLntiANYLFGGFGDAEYSNvSIIAITFII 185
Cdd:PRK03784 127 alLITLILLRFARRHRLSTSRLLLAGVALGIICSALmtwaVYFSTSLDLRQL---MYWMMGGFGGVDWRQ-SWLMLALLP 202

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 186 ALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSlGRQLAL 265
Cdd:PRK03784 203 VLIWLCCQGRPLNMLALGEISARQLGLPLWFWRNLLVLATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTDH-RVLLPG 281

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 499225284 266 NIVIGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLI 309
Cdd:PRK03784 282 CALAGASLLLLADIVARLALASAELPIGVVTATLGAPVFIWLLL 325
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
37-307 6.93e-17

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 79.75  E-value: 6.93e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284  37 ILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGS--GLALFLGLTTLWIPVFSITFSLI-TLI 113
Cdd:PRK10441  55 IVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGASFAIvlGAALFGYSSAQEQLAMAFAGALVaSLI 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 114 TVLVITSVLSQGYPVRiLILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFII 193
Cdd:PRK10441 135 VAFTGSQGGGQLSPVR-LTLAGVALAAVLEGLTSGIALLNPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLIAGATALLL 213

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 194 LNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRkWQWKQSLGRQLALNIVIGGQI 273
Cdd:PRK10441 214 SRALNSLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAVVGPIAFIGLMMPHMAR-WLVGADHRWSLPVTLLATPAL 292

                        250       260       270
                 ....*....|....*....|....*....|....
gi 499225284 274 MVMADFIGsHILSPVQIPASIIIALIGIPVLFYM 307
Cdd:PRK10441 293 LLFADIIG-RLLVPGELRVSVVSAFIGAPVLIFL 325
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
42-314 1.33e-13

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 70.12  E-value: 1.33e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284  42 RLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLwipvFSITFSLIT--LITVLVIT 119
Cdd:PRK10440  59 RLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDL----TAIALAAMAggIVTSLLVW 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 120 SVL-SQGYPVRILILSGLMIGALFNSLLYFLILLKPRKLN-TIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQL 197
Cdd:PRK10440 135 LLAwRNGIDTFRLIIIGIGVRAMLVAFNTWLLLKASLETAlTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRM 214

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499225284 198 KLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSLGrqLALNIVIGGQIMVMA 277
Cdd:PRK10440 215 RLLEMGDDTACALGVSVERSRLLLMLVAVVLTAAATALAGPISFIALVAPHIARRLSGTARWG--LTQAALCGALLLLAA 292

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 499225284 278 DFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKR 314
Cdd:PRK10440 293 DLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESRK 329
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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