|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
16-270 |
2.38e-58 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 188.48 E-value: 2.38e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 16 HEPPKRRRASLTVC-GLRAVETLGSiHPEKIHRFFFTPVRAKRFGPLCAYLAARKRLYRSANTQELERLTQSVHHQGVAA 94
Cdd:COG0566 16 RDKKYREEEGLFLAeGRHAVEEALK-AGREIEELLVTEGALDRLAELLALAKAAGIPVYEVSREVLDKLSGTETHQGVLA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 95 TIDEPRFPAVthSQVEFWVQRREFVVLLDRVGDAHNLGAIIRSAAFFGVHSLVVSDCRQqAQVTSATYRVAQGGMEFVQL 174
Cdd:COG0566 95 VVRPPEYADL--EDLLAEAGEPPLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRA-DPYNPKVVRASAGALFHVPV 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 175 LRCTNAQEVLEMCAGK-MTRVGASPHAFRSLTRLSnilsPEEAVILVLGNEETGLSEHLTAHCDHLCRIAGSGQVESLNV 253
Cdd:COG0566 172 ARVTNLADALEELKEAgFWVVGTDLDGEASLYEVD----LPGPVALVLGNEGKGLSRLVLEACDELVRIPMAGGVESLNV 247
|
250
....*....|....*..
gi 499183963 254 AQAGALFLSTIVQLRQS 270
Cdd:COG0566 248 AVAAAILLYEAARQRRA 264
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
118-264 |
1.40e-41 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 141.02 E-value: 1.40e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 118 FVVLLDRVGDAHNLGAIIRSAAFFGVHSLVVSDCRqqAQVTS-ATYRVAQGGMEFVQLLRCTNAQEVLEMC-AGKMTRVG 195
Cdd:cd18095 1 LVLVLDGVQDPGNLGTIIRTAAAFGVDGVILSKGT--VDPYNpKVVRASMGALFRLPIIRVDDLEELLEELkEAGYKVVA 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499183963 196 ASPHAFRSLTRLSNilspEEAVILVLGNEETGLSEHLTAHCDHLCRIAGSGQVESLNVAQAGALFLSTI 264
Cdd:cd18095 79 ADLDGGSSLYDLDL----PKPVALVLGNEGNGLSDELLELCDKRVTIPMSGGVESLNVAVAAAILLYEL 143
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
117-261 |
1.49e-41 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 141.13 E-value: 1.49e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 117 EFVVLLDRVGDAHNLGAIIRSAAFFGVHSLVVSDCRQQAQVTSATYRVAQGGMEFVQLLRCTNAQEVLEMCAGK-MTRVG 195
Cdd:pfam00588 1 PLVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEPRSADPYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAgYAVVA 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499183963 196 ASPHAfrslTRLSNILSPEEAViLVLGNEETGLSEHLTAHCDHLCRIAGSGQVESLNVAQAGALFL 261
Cdd:pfam00588 81 TSLGG----KSLYEIDFPKKVA-LVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIAL 141
|
|
| PRK10864 |
PRK10864 |
putative methyltransferase; Provisional |
11-262 |
3.38e-32 |
|
putative methyltransferase; Provisional
Pssm-ID: 236779 [Multi-domain] Cd Length: 346 Bit Score: 122.58 E-value: 3.38e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 11 RSQLSHEPPKRRRASLT-VCGLRAVETLGSIHPEKIHRFFFTPVRAKRFGPLCAYLAARKRLYRSANTQELERLTQSVHH 89
Cdd:PRK10864 93 KSFIDPEVLRRQRAEETrVYGENACQALFQSRPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEAELTKASGTEHH 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 90 QGVAATIDEPRfpavtHSQVEFWVQR---REFVVLLDRVGDAHNLGAIIRSAAFFGVHSLVVSDCrqqAQVTS-ATYRVA 165
Cdd:PRK10864 173 GGVCFLIKKRN-----GTDVQQWLAQagaQDCVLALEDVGNPHNLGGIMRSCAHFGVKGVVVQDA---ALLESgAAIRTA 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 166 QGGMEFVQLLRCTNAQEVLEMC--AGkMTRVGASPHAFRSLTRLSnilSPEEAViLVLGNEETGLSEHLTAHCDHLCRIA 243
Cdd:PRK10864 245 EGGAEHVQPITGDSFVDVLDDFrqAG-YTIVTTSSHKGTPLFKAS---LPAKMV-LVLGQEYDGLSDAARQQGDLSVSID 319
|
250
....*....|....*....
gi 499183963 244 GSGQVESLNVAQAGALFLS 262
Cdd:PRK10864 320 GTGNVESLNVSVATGVLLA 338
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
75-268 |
3.08e-29 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 112.05 E-value: 3.08e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 75 ANTQELERLTQSVHHQGVAATIDEPRFpavthSQVEFWVQRRE-----FVVLLDRVGDAHNLGAIIRSAAFFGVHsLVVS 149
Cdd:TIGR00186 48 VDRQKLDQLTKGGNHQGIAAKVKPILY-----KDLNDLYKTAKskkqpFLLILDEITDPHNLGAILRTAEAFGVD-GVIL 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 150 DCRQQAQVTSATYRVAQGGMEFVQLLRCTNAQEVLEmcagKMTRVG----ASPHAFRSLTRLSNILSPeeaVILVLGNEE 225
Cdd:TIGR00186 122 PKRRSAPLNSTVVKTSSGAVEYVPLARVTNLSRTIT----KLKESGfwtvGTDLDAQDTLYQVKLTKP---LALVVGNEG 194
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 499183963 226 TGLSEHLTAHCDHLCRIAGSGQVESLNVAQAGALFLSTIVQLR 268
Cdd:TIGR00186 195 EGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIKRQR 237
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
28-98 |
5.67e-09 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 51.77 E-value: 5.67e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 499183963 28 VCGLRAV-ETLGSihPEKIHRFFFTPVRAKRFGPLCAYLAARKRLYRSANTQELERLTQSVHHQGVAATIDE 98
Cdd:smart00967 1 IEGRHAVeEALKS--GRRIKELYLTEGRAERLKELLKLAKERGIKVIEVSKKELDKLSGTANHQGVVAVVKP 70
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
16-270 |
2.38e-58 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 188.48 E-value: 2.38e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 16 HEPPKRRRASLTVC-GLRAVETLGSiHPEKIHRFFFTPVRAKRFGPLCAYLAARKRLYRSANTQELERLTQSVHHQGVAA 94
Cdd:COG0566 16 RDKKYREEEGLFLAeGRHAVEEALK-AGREIEELLVTEGALDRLAELLALAKAAGIPVYEVSREVLDKLSGTETHQGVLA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 95 TIDEPRFPAVthSQVEFWVQRREFVVLLDRVGDAHNLGAIIRSAAFFGVHSLVVSDCRQqAQVTSATYRVAQGGMEFVQL 174
Cdd:COG0566 95 VVRPPEYADL--EDLLAEAGEPPLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRA-DPYNPKVVRASAGALFHVPV 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 175 LRCTNAQEVLEMCAGK-MTRVGASPHAFRSLTRLSnilsPEEAVILVLGNEETGLSEHLTAHCDHLCRIAGSGQVESLNV 253
Cdd:COG0566 172 ARVTNLADALEELKEAgFWVVGTDLDGEASLYEVD----LPGPVALVLGNEGKGLSRLVLEACDELVRIPMAGGVESLNV 247
|
250
....*....|....*..
gi 499183963 254 AQAGALFLSTIVQLRQS 270
Cdd:COG0566 248 AVAAAILLYEAARQRRA 264
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
118-264 |
1.40e-41 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 141.02 E-value: 1.40e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 118 FVVLLDRVGDAHNLGAIIRSAAFFGVHSLVVSDCRqqAQVTS-ATYRVAQGGMEFVQLLRCTNAQEVLEMC-AGKMTRVG 195
Cdd:cd18095 1 LVLVLDGVQDPGNLGTIIRTAAAFGVDGVILSKGT--VDPYNpKVVRASMGALFRLPIIRVDDLEELLEELkEAGYKVVA 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499183963 196 ASPHAFRSLTRLSNilspEEAVILVLGNEETGLSEHLTAHCDHLCRIAGSGQVESLNVAQAGALFLSTI 264
Cdd:cd18095 79 ADLDGGSSLYDLDL----PKPVALVLGNEGNGLSDELLELCDKRVTIPMSGGVESLNVAVAAAILLYEL 143
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
117-261 |
1.49e-41 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 141.13 E-value: 1.49e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 117 EFVVLLDRVGDAHNLGAIIRSAAFFGVHSLVVSDCRQQAQVTSATYRVAQGGMEFVQLLRCTNAQEVLEMCAGK-MTRVG 195
Cdd:pfam00588 1 PLVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEPRSADPYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAgYAVVA 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499183963 196 ASPHAfrslTRLSNILSPEEAViLVLGNEETGLSEHLTAHCDHLCRIAGSGQVESLNVAQAGALFL 261
Cdd:pfam00588 81 TSLGG----KSLYEIDFPKKVA-LVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIAL 141
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
118-264 |
2.43e-35 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 124.80 E-value: 2.43e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 118 FVVLLDRVGDAHNLGAIIRSAAFFGVHSLVVSDcRQQAQVTSATYRVAQGGMEFVQLLRCTNAQEVLEMCAGK-MTRVGA 196
Cdd:cd18103 1 LLLILDGITDPHNLGAIIRSAEAFGVDGVIIPK-RRSAPLTPTVAKASAGALEHLPIARVTNLARALEELKEAgFWIYGA 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499183963 197 SPHAFRSLTRLSnilsPEEAVILVLGNEETGLSEHLTAHCDHLCRIAGSGQVESLNVAQAGALFLSTI 264
Cdd:cd18103 80 DGEAEKSLYDVD----LTGPLALVLGSEGKGLRRLVLKNCDFLVKIPMAGKVDSLNVSVAAGIILYEI 143
|
|
| PRK10864 |
PRK10864 |
putative methyltransferase; Provisional |
11-262 |
3.38e-32 |
|
putative methyltransferase; Provisional
Pssm-ID: 236779 [Multi-domain] Cd Length: 346 Bit Score: 122.58 E-value: 3.38e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 11 RSQLSHEPPKRRRASLT-VCGLRAVETLGSIHPEKIHRFFFTPVRAKRFGPLCAYLAARKRLYRSANTQELERLTQSVHH 89
Cdd:PRK10864 93 KSFIDPEVLRRQRAEETrVYGENACQALFQSRPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEAELTKASGTEHH 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 90 QGVAATIDEPRfpavtHSQVEFWVQR---REFVVLLDRVGDAHNLGAIIRSAAFFGVHSLVVSDCrqqAQVTS-ATYRVA 165
Cdd:PRK10864 173 GGVCFLIKKRN-----GTDVQQWLAQagaQDCVLALEDVGNPHNLGGIMRSCAHFGVKGVVVQDA---ALLESgAAIRTA 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 166 QGGMEFVQLLRCTNAQEVLEMC--AGkMTRVGASPHAFRSLTRLSnilSPEEAViLVLGNEETGLSEHLTAHCDHLCRIA 243
Cdd:PRK10864 245 EGGAEHVQPITGDSFVDVLDDFrqAG-YTIVTTSSHKGTPLFKAS---LPAKMV-LVLGQEYDGLSDAARQQGDLSVSID 319
|
250
....*....|....*....
gi 499183963 244 GSGQVESLNVAQAGALFLS 262
Cdd:PRK10864 320 GTGNVESLNVSVATGVLLA 338
|
|
| SpoU-like_MRM1 |
cd18105 |
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose ... |
118-264 |
2.40e-29 |
|
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose residues G1145 to GmG residue of the mitochondrial 16S rRNA. MRM1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349978 Cd Length: 158 Bit Score: 109.92 E-value: 2.40e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 118 FVVLLDRVGDAHNLGAIIRSAAFFGVHSLVVSDcRQQAQVTSATYRVAQGGMEFVQLLRCTNAQEVLEMCAGKMTRV-GA 196
Cdd:cd18105 1 LWLLLDEITDPQNLGAILRSAYFLGVDGVVVSS-KNSAPLSPVVSKASAGALELMPIYSVDNLASFLKSSKENGWKVvGT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 197 SP-------HAFRSLTRLSNILsPEEAVILVLGNEETGLSEHLTAHCDHLCRIAGSGQ-----VESLNVAQAGALFLSTI 264
Cdd:cd18105 80 SAppsassdKKTIPANELSELL-LEKPTILVLGNEGRGLRTNIKNLCDYLVSIPGGRSaenpgVDSLNVSVAAGILLHSL 158
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
75-268 |
3.08e-29 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 112.05 E-value: 3.08e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 75 ANTQELERLTQSVHHQGVAATIDEPRFpavthSQVEFWVQRRE-----FVVLLDRVGDAHNLGAIIRSAAFFGVHsLVVS 149
Cdd:TIGR00186 48 VDRQKLDQLTKGGNHQGIAAKVKPILY-----KDLNDLYKTAKskkqpFLLILDEITDPHNLGAILRTAEAFGVD-GVIL 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 150 DCRQQAQVTSATYRVAQGGMEFVQLLRCTNAQEVLEmcagKMTRVG----ASPHAFRSLTRLSNILSPeeaVILVLGNEE 225
Cdd:TIGR00186 122 PKRRSAPLNSTVVKTSSGAVEYVPLARVTNLSRTIT----KLKESGfwtvGTDLDAQDTLYQVKLTKP---LALVVGNEG 194
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 499183963 226 TGLSEHLTAHCDHLCRIAGSGQVESLNVAQAGALFLSTIVQLR 268
Cdd:TIGR00186 195 EGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIKRQR 237
|
|
| SpoU-like_family |
cd18082 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
119-264 |
5.81e-21 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349955 Cd Length: 145 Bit Score: 87.28 E-value: 5.81e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 119 VVLLDRVGDAHNLGAIIRSAAFFGVHSLVVsdCRQQAQVTSA-TYRVAQGGMEFVQLLRCTNAQEVLE--MCAGK----- 190
Cdd:cd18082 1 HLVLDNIRSPGNIGSIFRTADAFGVEKIYL--VGPTADIFDPkAKRTSRGTHFSVPYERVDNFEEYLKslKEEGYpligl 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499183963 191 -MTRVGASPHAFRsltrlsniLSPEEAVILVLGNEETGLSEHLTAHCDHLCRIAGSGQVESLNVAQAGALFLSTI 264
Cdd:cd18082 79 eLTDGSIPLSEFK--------FKKPKKIALIFGNERSGLSPELLALCDYTVHIPMSGKNSSLNVSVATGIALYEF 145
|
|
| SpoU-like_AviRb |
cd18107 |
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes ... |
118-261 |
6.45e-17 |
|
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes methylates the 2'-O atom of U2479 of the 23S ribosomal RNA. AviRb is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349980 Cd Length: 148 Bit Score: 76.27 E-value: 6.45e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 118 FVVLLDRVGDAHNLGAIIRSAAFFGVHSLVVS----DCRQQAQVTSATyrvaqGGMEFVQLLRCTNAQEVLEMCAGKMTR 193
Cdd:cd18107 1 LVVLFDRPTSPGNLGTIIRSADALGAHGLVVTghaaDVYDPKTIRAST-----GSLFSLPIVRVPSNRELEDWVEARKAR 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499183963 194 ------VGASPHAFRSLTRlSNILSPeeaVILVLGNEETGLSEHLTAHCDHLCRIAGSGQVESLNVAQAGALFL 261
Cdd:cd18107 76 gtplqlVGTDEHGDHQIAD-HDFTRP---TLLLIGNETAGLSAAWRELCDETVSIPMAGSASSLNAACAASIFL 145
|
|
| SpoU-like_RNA-MTase |
cd18109 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
118-264 |
1.36e-16 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349982 Cd Length: 141 Bit Score: 75.27 E-value: 1.36e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 118 FVVLLDRVGDAHNLGAIIRSAAFFGVHSLVVS-DCrqqAQVTSA-TYRVAQGGMEFVQLLRCtNAQEVLEMCAGKMTRVG 195
Cdd:cd18109 1 LTLALDGIQDPGNLGTIIRTADWFGIRQIICSpDT---VDPYNPkVVQASMGSIFRVQIHYT-DLPALLAELKKAFPVYG 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 196 ASPHAfRSLTRLSnilsPEEAVILVLGNEETGLSEHLTAHCDHLCRIAGSGQ-VESLNVAQAGALFLSTI 264
Cdd:cd18109 77 ADLDG-ENLYEFT----LPEKGILVMGNEGHGISPEVLKLLTHRLTIPRYGKgAESLNVAVATAILLSEF 141
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
30-270 |
1.40e-16 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 77.70 E-value: 1.40e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 30 GLRAVETLGSIHPEKIHRFFFTPVRA-KRFGPLCAYLAARKRLYRSANTQELERLTQSVHHQGVAATIDEPRfpAVTHSQ 108
Cdd:PRK11181 7 GIHAVQALLERAPERFIEVFVLKGREdKRLLPLINELEAQGIVIQLANRQTLDEKAEGAVHQGIIARVKPGR--QLQEND 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 109 VEFWVQRRE--FVVLLDRVGDAHNLGAIIRSAAFFGVHSLVVSDCRqQAQVTSATYRVAQGGMEFVQLLRCTN-AQEVLE 185
Cdd:PRK11181 85 LPDLLASLEqpFLLILDGVTDPHNLGACLRSADAAGVHAVIVPKDR-SAQLNATAKKVACGAAETVPLIRVTNlARTMRM 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 186 MCAGKMTRVGASPHAFRSL--TRLSNILSpeeaviLVLGNEETGLSEHLTAHCDHLCRIAGSGQVESLNVAQAGALFLST 263
Cdd:PRK11181 164 LQEKNIWIVGTAGEADHTLyqSKLTGPLA------LVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICLFE 237
|
....*..
gi 499183963 264 IVQLRQS 270
Cdd:PRK11181 238 AVRQRSA 244
|
|
| SpoU-like_TrmH |
cd18092 |
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group ... |
116-268 |
9.17e-16 |
|
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of the ribose of the universally conserved guanosine 18 (G18) position in tRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349965 Cd Length: 162 Bit Score: 73.27 E-value: 9.17e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 116 REFVVLLDRVGDAHNLGAIIRSAAFFGVHSLVVSDCRQQAQVTSatyRVAQGGMEFVQLLRCTNAQEVLE-MCAGKMTRV 194
Cdd:cd18092 15 RDLTVVLENVHDPHNASAVLRTCDAFGVQDVHVIEPKNKFKKNR---GVAMGADKWLDVHRHDSTEECLAaLKEQGYRIV 91
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499183963 195 GASPHAfrsltrlsNILSPEEAVI-----LVLGNEETGLSEHLTAHCDHLCRIAGSGQVESLNVAQAGALFLSTIVQLR 268
Cdd:cd18092 92 ATSLSP--------DAVPLDELDYtrptaLVFGNEKDGVSEEALAAADERVYIPMYGFVESLNVSVAAAIILYELQRQR 162
|
|
| SpoU-like |
cd18097 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
119-258 |
3.15e-14 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349970 Cd Length: 144 Bit Score: 68.75 E-value: 3.15e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 119 VVLLDRVGDAHNLGAIIRSAAFFGVHSLVV---SDCRQQAQVTsatyRVAQGGMEFVQLLRCTNAQEVLEMCAGKMTRVG 195
Cdd:cd18097 2 VVVLDNLRSAHNVGSIFRTADAAGVEKIYLcgyTPTPPHPKVA----KTALGAEESVPWEHFEDTLEAVRALKARGYTII 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499183963 196 A---SPHAfRSLTRLSnilsPEEAVILVLGNEETGLSEHLTAHCDHLCRIAGSGQVESLNVAQAGA 258
Cdd:cd18097 78 AletTENS-VPLHEAR----LPRPLALVLGNEVRGVSPEVLALCDAVVEIPMFGRKNSLNVAVAAA 138
|
|
| SpoU-like_RNA-MTase |
cd18104 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
118-261 |
1.14e-13 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349977 Cd Length: 146 Bit Score: 67.22 E-value: 1.14e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 118 FVVLLDRVGDAHNLGAIIRSAAFFGVHSLVVSDCR---QQAQVTsatyRVAQGGMEFVQLLRCTNAQEVLEMCAGKMTRV 194
Cdd:cd18104 1 LILVLEGLEKPGNLGAILRSADAAGADAVILCDPKtdlFNPNVI----RASLGAVFTLPVAEASSEETLAWLKENKIRIL 76
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499183963 195 GASPHAFRSLTRlSNILSPeeaVILVLGNEETGLSEHLTAHCDHLCRIAGSGQVESLNVAQAGALFL 261
Cdd:cd18104 77 ATTPKAEKLYYE-ADLRGP---IAIVVGSESEGLSEFWLKAADERVRIPMAGQADSLNVSVAAAILL 139
|
|
| SpoU_sub_bind |
pfam08032 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
28-100 |
7.41e-12 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 429793 [Multi-domain] Cd Length: 74 Bit Score: 59.95 E-value: 7.41e-12
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499183963 28 VCGLRAVETLGSIHPEkIHRFFFTP-VRAKRFGPLCAYLAARKRLYRSANTQELERLTQSVHHQGVAATIDEPR 100
Cdd:pfam08032 2 IYGRHAVLEALKSGPE-IKKLYLTEgRRDPRLKELLKLAKERGIKVEEVDRKKLDKLSGTANHQGVVAEVKPYE 74
|
|
| SpoU-like_TrmJ |
cd18093 |
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl ... |
128-261 |
5.30e-11 |
|
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 32 in both tRNASer1 and tRNAGln2. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349966 Cd Length: 153 Bit Score: 59.82 E-value: 5.30e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 128 AHNLGAIIRSAAFFGVHSLVVSDCRQqAQVTSATYRVAQGGmefVQLLRctNAQEV---LEMCAGKMTRVGASPhafRSL 204
Cdd:cd18093 11 PGNIGAVARAMKNFGLSDLRLVNPRC-DDPEEAARALASGA---EDVLE--NAKVYdtlEEALADCDLVVATTA---RPR 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 205 TRLSNILSPEEAVI------------LVLGNEETGLS-EHLtAHCDHLCRIAGSGQVESLNVAQAGALFL 261
Cdd:cd18093 82 GLRRPLLTPRELAEllkehaaggkvaLVFGREDSGLTnEEL-ALCDLLVTIPTNPEYPSLNLAQAVAIVL 150
|
|
| SpoU-like |
cd18096 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
118-261 |
8.78e-11 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349969 Cd Length: 140 Bit Score: 59.15 E-value: 8.78e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 118 FVVLLDRVGDAHNLGAIIRSAAFFGVHSLVVSDCRQQAqvtsatYRVAQGGMEFVQLLRCTNAQEVLEMCAGKMTRV--- 194
Cdd:cd18096 1 LYLVLHNVAKRHNIGTIVRSANAFGVKEVHLVGRRKFN------PFGAMGTDRHVKFRHFDTLAEAKEYLKERGIRLvgv 74
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499183963 195 ----GASP---HAFRSLTrlsnilspeeavILVLGNEETGLSEHLTAHCDHLCRIAGSGQ-VESLNVAQAGALFL 261
Cdd:cd18096 75 eivpGAEPietHPFPGDT------------AFVLGNEGTGLSDEQLAICDGFVYIPQYGSgTASLNVSVAASIVL 137
|
|
| SpoU-like_TRM3-like |
cd18091 |
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O) ... |
121-261 |
6.19e-10 |
|
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O)-methyltransferase TRM3 catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in various tRNAs. TRM3 is similar to C-terminal domain of TAR (HIV-1) RNA binding protein 1 (TARBP1), a protein binding to TAR, which functions as a RNA regulatory signal by forming a stable stem-loop structure to which transactivator protein Tat binds. The role of TARBP1 is believed to be to disengage RNA polymerase II from TAR during transcriptional elongation. TRM3 and the C-terminal methyltransferase domain of TARBP1 are members of the SPOUT methyltransferase superfamily.
Pssm-ID: 349964 Cd Length: 145 Bit Score: 56.77 E-value: 6.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 121 LLDRVgdaHNLGAIIRSAAFFGVHSLVVSDCR--QQAQVTSATyRVAQGGMEFVQLLRCTNAQEVLEMCAGKMTRVGASP 198
Cdd:cd18091 7 LIDKP---PNLGGLCRTCEIFGVSKLVLPNLAvvEDKQFKALS-VSAEKWLPIEEVKPEDLLPYLKEKKQEGYTIVGLEQ 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499183963 199 HAfRSlTRLSNILSPEEAViLVLGNEETGLSEHLTAHCDHLCRIAGSGQVESLNVAQAGALFL 261
Cdd:cd18091 83 TA-NS-VSLHDFQFPKKTV-LVLGNEKEGIPAELLSLLDVCVEIPQLGVIRSLNVHVSGAIAI 142
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
28-98 |
5.67e-09 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 51.77 E-value: 5.67e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 499183963 28 VCGLRAV-ETLGSihPEKIHRFFFTPVRAKRFGPLCAYLAARKRLYRSANTQELERLTQSVHHQGVAATIDE 98
Cdd:smart00967 1 IEGRHAVeEALKS--GRRIKELYLTEGRAERLKELLKLAKERGIKVIEVSKKELDKLSGTANHQGVVAVVKP 70
|
|
| PRK11081 |
PRK11081 |
tRNA guanosine-2'-O-methyltransferase; Provisional |
120-290 |
6.17e-08 |
|
tRNA guanosine-2'-O-methyltransferase; Provisional
Pssm-ID: 236837 [Multi-domain] Cd Length: 229 Bit Score: 52.30 E-value: 6.17e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 120 VLLDRVGDAHNLGAIIRSAAFFGVHSL--VVSDcrQQAQVTSATyrvAQGGMEFVQLLRCTN-AQEVLEMCAGKMTRVGA 196
Cdd:PRK11081 22 VCMEQVHKPHNVSAIIRTADAVGVHEVhaVWPG--SRMRTMGST---AAGSNSWVQVKTHRTiGDAVAHLKGQGMQILAT 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 197 --SPHA--FRSL--TRLSNILspeeavilvLGNEETGLSEHLTAHCDHLCRIAGSGQVESLNVAQAGALFLSTIVQLRQS 270
Cdd:PRK11081 97 hlSDTAvdFREIdyTRPTCIL---------MGQEKTGISQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
|
170 180
....*....|....*....|
gi 499183963 271 PQDYTQGHRATPraQERVHR 290
Cdd:PRK11081 168 AGMYLRENSMLP--EEEQQR 185
|
|
| SpoU-like_NHR |
cd18108 |
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) ... |
119-261 |
1.81e-07 |
|
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) confers resistance to the thiazole antibiotic nosiheptide via catalyzing 2'O-methylation of 23S rRNA at the nucleotide A1067. NHR is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349981 Cd Length: 144 Bit Score: 49.78 E-value: 1.81e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 119 VVLLDRVGDAHNLGAIIRSAAFFGVHSLVVSDcrqqAQVTSATYR---------------VAQGGMEFVQLLRcTNAQEV 183
Cdd:cd18108 2 VVVLDGVRIVGNIGAIVRTSLALGAAGIVLVD----SDLATVADRrllrasrgyvfslpvVLADREEAVAFLR-DNDIPL 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499183963 184 LEMCAGKMTRVgasphafRSLTRLSnilspeEAVILVLGNEETGLSEHLTAHCDHLCRIAGSGQVESLNVAQAGALFL 261
Cdd:cd18108 77 MTLDADGDVPV-------KELGDRP------DRLALVFGSEKGGPSGLFEEAAAGTVSIPMSSSTESLNVSVSAGIAL 141
|
|
| SpoU-like |
cd18098 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
118-261 |
1.88e-06 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349971 Cd Length: 138 Bit Score: 46.49 E-value: 1.88e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 118 FVVLLDRVGDAHNLGAIIRSAAFFGVHSLVVSDCR--QQAQVTSATYRVAQGGM----EFVQLLRCTNAQEVL---EMCa 188
Cdd:cd18098 1 FAIGIENPKTPKNVGTLWRAAGCLGASFVFTIGARykRRKQSTDTSKAWRHIPLfhydDLEDLAEPLPFGAVLvavELT- 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499183963 189 gkmtrVGASPhafrsltrLSNILSPEEAVILvLGNEETGLSEHLTAHCDHLCRIAGSGqveSLNVAQAGALFL 261
Cdd:cd18098 80 -----EGATP--------LPDFKHPDRAVYL-LGPEDGGLPQEVLARCHHVVYLPTRG---SLNVAVAGSIVL 135
|
|
| SpoU-like_TrmL |
cd18094 |
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL ... |
130-269 |
3.03e-05 |
|
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349967 Cd Length: 145 Bit Score: 43.21 E-value: 3.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 130 NLGAIIRSAAFFGV--HsLV------VSDcrqqaqvtsatYRVAQGGM---EFVQLLRCTNAQEVLEMCAGKmtR-VGAS 197
Cdd:cd18094 12 NTGNIARTCAATGArlH-LIeplgfsLDD-----------KRLKRAGLdywDHVDLTVHDSWEAFLEALPPG--RlFLFT 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499183963 198 PHAFRSLTRLSnilsPEEAVILVLGNEETGLSEH-LTAHCDHLCRIAGSGQVESLNVAQAGALFLSTIvqLRQ 269
Cdd:cd18094 78 TKGTKPYTDFD----FKPGDYLVFGRESTGLPEEiLDAFPDRRLRIPMRPKVRSLNLSNSVAIVLYEA--LRQ 144
|
|
| SpoU-like_RNMTL1 |
cd18106 |
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) ... |
120-261 |
6.66e-05 |
|
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) catalyzes the methylation of 2'-O-ribose residues G1370 to GmG residue of the mitochondrial 16S rRNA. RNMTL1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349979 Cd Length: 148 Bit Score: 42.24 E-value: 6.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 120 VLLDRVGDAHNLGAIIRSAAFFGVHSLVVSdcrqqaqvtsatyrvaQGgmefvqllrCTNAQEVlemcagKMTRVGASPH 199
Cdd:cd18106 3 VICDNIRDPGNLGSILRSAAAAGCSKVLLT----------------KG---------CVDPWEP------KVLRAGAGAH 51
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 200 aFR-------SLTRLSNILSPEEAV----------------------ILVLGNEETGLSE--HLTAHCDHLCR--IAGSG 246
Cdd:cd18106 52 -FRlpiygnlSWDDIPNYLPDDSKVfladnnlpvqpydsidycsgpiVLVIGGETHGVSPeaYKLAHSTGGSRvhIPLAN 130
|
170
....*....|....*
gi 499183963 247 QVESLNVAQAGALFL 261
Cdd:cd18106 131 GVDSLNSAVAASILL 145
|
|
| TrmJ |
COG0565 |
tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase [Translation, ... |
210-296 |
7.46e-05 |
|
tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase [Translation, ribosomal structure and biogenesis]; tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440331 [Multi-domain] Cd Length: 237 Bit Score: 43.18 E-value: 7.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499183963 210 ILSPEEA------------VILVLGNEETGLS-EHLtAHCDHLCRIAGSGQVESLNVAQAGALFLSTIVQLRQSPQDYTQ 276
Cdd:COG0565 89 VLTPREAaeellaraaggkVALVFGRERSGLTnEEL-ALCDALVTIPTNPEYPSLNLAQAVQVVAYELRKAALEAPPLPP 167
|
90 100
....*....|....*....|.
gi 499183963 277 GHRATPRAQERVHRC-GQLEE 296
Cdd:COG0565 168 PPEPEPATAEELEGLyEHLEE 188
|
|
| |
