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Conserved domains on  [gi|498913420|ref|WP_010848593|]
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DUF423 domain-containing protein [Xenorhabdus nematophila]

Protein Classification

DUF423 domain-containing protein( domain architecture ID 10013669)

DUF423 domain-containing protein similar to Escherichia coli UPF0382 inner membrane protein YgdD

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK10873 PRK10873
hypothetical protein; Provisional
1-131 3.93e-66

hypothetical protein; Provisional


:

Pssm-ID: 182798  Cd Length: 131  Bit Score: 196.46  E-value: 3.93e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498913420   1 MSSRAMLIFVGISGFFYVALGAMGAHMLAPVLTSRQMEWIHTGLQYQGLHTLAMMALAVLSTRQPVAQFGWSGIFFLVGI 80
Cdd:PRK10873   1 MTSRFMLIFAAISGFIYVALGAFGAHVLSKTLGAVEMGWIQTGLEYQAFHTLAILGLAVAMQRRISIWFYWSSVFLALGT 80
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 498913420  81 MLFSGSLYCLAFLPLKFLVYLTPIGGVSFLIGWLCVLIGALRLRKSALSHE 131
Cdd:PRK10873  81 VLFSGSLYCLALSHLRLWAYITPVGGVSFLAGWALMLIGALRLKKKAESHE 131
 
Name Accession Description Interval E-value
PRK10873 PRK10873
hypothetical protein; Provisional
1-131 3.93e-66

hypothetical protein; Provisional


Pssm-ID: 182798  Cd Length: 131  Bit Score: 196.46  E-value: 3.93e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498913420   1 MSSRAMLIFVGISGFFYVALGAMGAHMLAPVLTSRQMEWIHTGLQYQGLHTLAMMALAVLSTRQPVAQFGWSGIFFLVGI 80
Cdd:PRK10873   1 MTSRFMLIFAAISGFIYVALGAFGAHVLSKTLGAVEMGWIQTGLEYQAFHTLAILGLAVAMQRRISIWFYWSSVFLALGT 80
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 498913420  81 MLFSGSLYCLAFLPLKFLVYLTPIGGVSFLIGWLCVLIGALRLRKSALSHE 131
Cdd:PRK10873  81 VLFSGSLYCLALSHLRLWAYITPVGGVSFLAGWALMLIGALRLKKKAESHE 131
YgdD COG2363
Uncharacterized membrane protein YgdD, TMEM256/DUF423 family [Function unknown];
1-126 5.81e-40

Uncharacterized membrane protein YgdD, TMEM256/DUF423 family [Function unknown];


Pssm-ID: 441930  Cd Length: 126  Bit Score: 129.91  E-value: 5.81e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498913420   1 MSSRAMLIFVGISGFFYVALGAMGAHMLAPVLTSRQMEWIHTGLQYQGLHTLAMMALAVLSTRQPVAQFGWSGIFFLVGI 80
Cdd:COG2363    1 MMMRLFLILGALLGALAVALGAFGAHGLKGRLSPEALATFETAVRYQMYHALALLALGLLAQRLPSRLLRLAGWLFLLGI 80
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 498913420  81 MLFSGSLYCLAFLPLKFLVYLTPIGGVSFLIGWLCVLIGALRLRKS 126
Cdd:COG2363   81 LLFSGSLYALALTGIKLLGAITPIGGLLFILGWLLLAIAALRLKRR 126
DUF423 pfam04241
Protein of unknown function (DUF423); This family of proteins with unknown function is a ...
20-106 4.32e-23

Protein of unknown function (DUF423); This family of proteins with unknown function is a possible integral membrane protein from Caenorhabditis elegans. This family of proteins has GO references indicating the protein is involved in nematode larval development and is a positive regulator of growth rate.


Pssm-ID: 461234  Cd Length: 86  Bit Score: 85.65  E-value: 4.32e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498913420   20 LGAMGAHMLAPVltSRQMEWIHTGLQYQGLHTLAMMALAVLSTRQPVAQ-FGWSGIFFLVGIMLFSGSLYCLAFLPLKFL 98
Cdd:pfam04241   1 LGAFGAHGLKAR--PEQLAVFETAVQYQMYHALALLAVALLARGAPRARlLNLAGWLFLAGIVLFSGSLYALALTGIKWL 78

                  ....*...
gi 498913420   99 VYLTPIGG 106
Cdd:pfam04241  79 GPITPIGG 86
 
Name Accession Description Interval E-value
PRK10873 PRK10873
hypothetical protein; Provisional
1-131 3.93e-66

hypothetical protein; Provisional


Pssm-ID: 182798  Cd Length: 131  Bit Score: 196.46  E-value: 3.93e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498913420   1 MSSRAMLIFVGISGFFYVALGAMGAHMLAPVLTSRQMEWIHTGLQYQGLHTLAMMALAVLSTRQPVAQFGWSGIFFLVGI 80
Cdd:PRK10873   1 MTSRFMLIFAAISGFIYVALGAFGAHVLSKTLGAVEMGWIQTGLEYQAFHTLAILGLAVAMQRRISIWFYWSSVFLALGT 80
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 498913420  81 MLFSGSLYCLAFLPLKFLVYLTPIGGVSFLIGWLCVLIGALRLRKSALSHE 131
Cdd:PRK10873  81 VLFSGSLYCLALSHLRLWAYITPVGGVSFLAGWALMLIGALRLKKKAESHE 131
YgdD COG2363
Uncharacterized membrane protein YgdD, TMEM256/DUF423 family [Function unknown];
1-126 5.81e-40

Uncharacterized membrane protein YgdD, TMEM256/DUF423 family [Function unknown];


Pssm-ID: 441930  Cd Length: 126  Bit Score: 129.91  E-value: 5.81e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498913420   1 MSSRAMLIFVGISGFFYVALGAMGAHMLAPVLTSRQMEWIHTGLQYQGLHTLAMMALAVLSTRQPVAQFGWSGIFFLVGI 80
Cdd:COG2363    1 MMMRLFLILGALLGALAVALGAFGAHGLKGRLSPEALATFETAVRYQMYHALALLALGLLAQRLPSRLLRLAGWLFLLGI 80
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 498913420  81 MLFSGSLYCLAFLPLKFLVYLTPIGGVSFLIGWLCVLIGALRLRKS 126
Cdd:COG2363   81 LLFSGSLYALALTGIKLLGAITPIGGLLFILGWLLLAIAALRLKRR 126
DUF423 pfam04241
Protein of unknown function (DUF423); This family of proteins with unknown function is a ...
20-106 4.32e-23

Protein of unknown function (DUF423); This family of proteins with unknown function is a possible integral membrane protein from Caenorhabditis elegans. This family of proteins has GO references indicating the protein is involved in nematode larval development and is a positive regulator of growth rate.


Pssm-ID: 461234  Cd Length: 86  Bit Score: 85.65  E-value: 4.32e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498913420   20 LGAMGAHMLAPVltSRQMEWIHTGLQYQGLHTLAMMALAVLSTRQPVAQ-FGWSGIFFLVGIMLFSGSLYCLAFLPLKFL 98
Cdd:pfam04241   1 LGAFGAHGLKAR--PEQLAVFETAVQYQMYHALALLAVALLARGAPRARlLNLAGWLFLAGIVLFSGSLYALALTGIKWL 78

                  ....*...
gi 498913420   99 VYLTPIGG 106
Cdd:pfam04241  79 GPITPIGG 86
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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