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Conserved domains on  [gi|498112210|ref|WP_010426366|]
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MULTISPECIES: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [Enterobacter]

Protein Classification

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase( domain architecture ID 11478026)

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase (GPDH) catalyzes the interconversion of glycerone phosphate and sn-glycerol-3-phosphate

EC:  1.1.1.94
Gene Ontology:  GO:0051287|GO:0047952|GO:0009331|GO:0046167
SCOP:  4000111

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
gpsA PRK00094
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase;
10-330 0e+00

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase;


:

Pssm-ID: 234629 [Multi-domain]  Cd Length: 325  Bit Score: 550.44  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  10 VIGAGSYGTALAITLARNGHDVVLWGHDPKHIATLQRDRCNVAFLPDVPFPDSLHLESDLATALAASRNILIVVPSHVFG 89
Cdd:PRK00094   6 VLGAGSWGTALAIVLARNGHDVTLWARDPEQAAEINADRENPRYLPGIKLPDNLRATTDLAEALADADLILVAVPSQALR 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  90 EVLRQIKPLMRPDARIVWATKGLEAETGRLLQDVAREALGDDIPLAVISGPTFAKELAAGLPTAISLASTDQAFSDDLQQ 169
Cdd:PRK00094  86 EVLKQLKPLLPPDAPIVWATKGIEPGTGKLLSEVLEEELPDLAPIAVLSGPSFAKEVARGLPTAVVIASTDEELAERVQE 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210 170 LLHCGkSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMSRLGAALGADPATFMGMAGLGDL 249
Cdd:PRK00094 166 LFHSP-YFRVYTNTDVIGVELGGALKNVIAIAAGIADGLGLGDNARAALITRGLAEITRLGVALGANPETFLGLAGLGDL 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210 250 VLTCTDNQSRNRRFGMMLGQGSDVKSAQEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLG 329
Cdd:PRK00094 245 VLTCTSPLSRNRRFGLALGQGKSLEEALAEIGMVAEGVRTAKAVYELAKKLGVEMPITEAVYAVLYEGKDPREAVEDLMG 324


                 .
gi 498112210 330 R 330
Cdd:PRK00094 325 R 325
 
Name Accession Description Interval E-value
gpsA PRK00094
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase;
10-330 0e+00

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase;


Pssm-ID: 234629 [Multi-domain]  Cd Length: 325  Bit Score: 550.44  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  10 VIGAGSYGTALAITLARNGHDVVLWGHDPKHIATLQRDRCNVAFLPDVPFPDSLHLESDLATALAASRNILIVVPSHVFG 89
Cdd:PRK00094   6 VLGAGSWGTALAIVLARNGHDVTLWARDPEQAAEINADRENPRYLPGIKLPDNLRATTDLAEALADADLILVAVPSQALR 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  90 EVLRQIKPLMRPDARIVWATKGLEAETGRLLQDVAREALGDDIPLAVISGPTFAKELAAGLPTAISLASTDQAFSDDLQQ 169
Cdd:PRK00094  86 EVLKQLKPLLPPDAPIVWATKGIEPGTGKLLSEVLEEELPDLAPIAVLSGPSFAKEVARGLPTAVVIASTDEELAERVQE 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210 170 LLHCGkSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMSRLGAALGADPATFMGMAGLGDL 249
Cdd:PRK00094 166 LFHSP-YFRVYTNTDVIGVELGGALKNVIAIAAGIADGLGLGDNARAALITRGLAEITRLGVALGANPETFLGLAGLGDL 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210 250 VLTCTDNQSRNRRFGMMLGQGSDVKSAQEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLG 329
Cdd:PRK00094 245 VLTCTSPLSRNRRFGLALGQGKSLEEALAEIGMVAEGVRTAKAVYELAKKLGVEMPITEAVYAVLYEGKDPREAVEDLMG 324


                 .
gi 498112210 330 R 330
Cdd:PRK00094 325 R 325
GpsA COG0240
Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate ...
 10-333 0e+00

Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate dehydrogenase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 440010 [Multi-domain]  Cd Length: 327  Bit Score: 525.37  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  10 VIGAGSYGTALAITLARNGHDVVLWGHDPKHIATLQRDRCNVAFLPDVPFPDSLHLESDLATALAASRNILIVVPSHVFG 89
Cdd:COG0240    5 VLGAGSWGTALAKVLARNGHEVTLWGRDPEVAEEINETRENPRYLPGVKLPENLRATSDLEEALAGADLVLLAVPSQALR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  90 EVLRQIKPLMRPDARIVWATKGLEAETGRLLQDVAREALGDDIPLAVISGPTFAKELAAGLPTAISLASTDQAFSDDLQQ 169
Cdd:COG0240   85 EVLEQLAPLLPPGAPVVSATKGIEPGTGLLMSEVIAEELPGALRIAVLSGPSFAEEVARGLPTAVVVASEDEEVAERLQE 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210 170 LLHCgKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMSRLGAALGADPATFMGMAGLGDL 249
Cdd:COG0240  165 LLST-PYFRVYTSDDVIGVELGGALKNVIAIAAGIADGLGLGDNARAALITRGLAEMTRLGVALGARPETFMGLAGLGDL 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210 250 VLTCTDNQSRNRRFGMMLGQGSDVKSAQEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLG 329
Cdd:COG0240  244 VLTCTSDLSRNRRFGLALGKGKSLEEALAEMGMVAEGVYTAKAVYELAEKLGVEMPITEAVYAVLYEGKSPREAVEALMA 323


                 ....
gi 498112210 330 RARK 333
Cdd:COG0240  324 RPLK 327
NAD_Gly3P_dh_C pfam07479
NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent ...
 184-323 2.29e-77

NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase (GPDH) catalyzes the interconversion of dihydroxyacetone phosphate and L-glycerol-3-phosphate. This family represents the C-terminal substrate-binding domain.


Pssm-ID: 462178 [Multi-domain]  Cd Length: 142  Bit Score: 233.43  E-value: 2.29e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  184 DFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMSRLGAALGADPATFMGMAGLGDLVLTCTDNQSRNRRF 263
Cdd:pfam07479   1 DVIGVELGGALKNVIAIAAGIADGLGLGDNAKAALITRGLAEMIRLGKALGAKPETFFGLAGLGDLIVTCTSGLSRNRRF 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  264 GMMLGQGSDVKSAQEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREA 323
Cdd:pfam07479  81 GEALGKGKSLEEAEKELGQVAEGVYTAKAVYELAKKLGVEMPIFEAVYRILYEGKSPEEA 140
glycerol3P_DH TIGR03376
glycerol-3-phosphate dehydrogenase (NAD(+)); Members of this protein family are the eukaryotic ...
 10-317 4.01e-55

glycerol-3-phosphate dehydrogenase (NAD(+)); Members of this protein family are the eukaryotic enzyme, glycerol-3-phosphate dehydrogenase (NAD(+)) (EC 1.1.1.8). Enzymatic activity for 1.1.1.8 is defined as sn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADH. Note the very similar reactions of enzymes defined as EC 1.1.1.94 and 1.1.99.5, assigned to families of proteins in the bacteria.


Pssm-ID: 274551 [Multi-domain]  Cd Length: 342  Bit Score: 183.31  E-value: 4.01e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210   10 VIGAGSYGTALAITLARNG--------HDVVLWGHDPKHIAT-----LQRDRCNVAFLPDVPFPDSLHLESDLATALAAS 76
Cdd:TIGR03376   4 VVGSGNWGTAIAKIVAENAralpelfeESVRMWVFEEEIEGRnlteiINTTHENVKYLPGIKLPANLVAVPDLVEAAKGA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210   77 RNILIVVPSHVFGEVLRQIKPLMRPDARIVWATKGLE--AETGRLLQDVAREALGddIPLAVISGPTFAKELAAGLPTAI 154
Cdd:TIGR03376  84 DILVFVIPHQFLEGICKQLKGHVKPNARAISCIKGLEvsKDGVKLLSDIIEEELG--IPCGVLSGANLANEVAKEKFSET 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  155 SLASTDQAFSDD----LQQLLHcGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMSRLG 230
Cdd:TIGR03376 162 TVGYRDPADFDVdarvLKALFH-RPYFRVNVVDDVAGVEIAGALKNVVAIAAGFVDGLGWGDNAKAAVMRRGLLEMIKFA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  231 AALG--ADPATFMGMAGLGDLVLTCTDnqSRNRRFGMMLGQGSdvKSAQE-----KIGQVVEGYRNTKEVRELAHRFGV- 302
Cdd:TIGR03376 241 RMFFptGEVTFTFESCGVADLITTCLG--GRNFKVGRAFAKTG--KSLEElekelLNGQSLQGVATAKEVHELLKNKNKd 316

                         330
                  ....*....|....*.
gi 498112210  303 -EMPITEEIYQVLYCG 317
Cdd:TIGR03376 317 dEFPLFEAVYQILYEG 332
 
Name Accession Description Interval E-value
gpsA PRK00094
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase;
10-330 0e+00

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase;


Pssm-ID: 234629 [Multi-domain]  Cd Length: 325  Bit Score: 550.44  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  10 VIGAGSYGTALAITLARNGHDVVLWGHDPKHIATLQRDRCNVAFLPDVPFPDSLHLESDLATALAASRNILIVVPSHVFG 89
Cdd:PRK00094   6 VLGAGSWGTALAIVLARNGHDVTLWARDPEQAAEINADRENPRYLPGIKLPDNLRATTDLAEALADADLILVAVPSQALR 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  90 EVLRQIKPLMRPDARIVWATKGLEAETGRLLQDVAREALGDDIPLAVISGPTFAKELAAGLPTAISLASTDQAFSDDLQQ 169
Cdd:PRK00094  86 EVLKQLKPLLPPDAPIVWATKGIEPGTGKLLSEVLEEELPDLAPIAVLSGPSFAKEVARGLPTAVVIASTDEELAERVQE 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210 170 LLHCGkSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMSRLGAALGADPATFMGMAGLGDL 249
Cdd:PRK00094 166 LFHSP-YFRVYTNTDVIGVELGGALKNVIAIAAGIADGLGLGDNARAALITRGLAEITRLGVALGANPETFLGLAGLGDL 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210 250 VLTCTDNQSRNRRFGMMLGQGSDVKSAQEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLG 329
Cdd:PRK00094 245 VLTCTSPLSRNRRFGLALGQGKSLEEALAEIGMVAEGVRTAKAVYELAKKLGVEMPITEAVYAVLYEGKDPREAVEDLMG 324


                 .
gi 498112210 330 R 330
Cdd:PRK00094 325 R 325
GpsA COG0240
Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate ...
 10-333 0e+00

Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate dehydrogenase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 440010 [Multi-domain]  Cd Length: 327  Bit Score: 525.37  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  10 VIGAGSYGTALAITLARNGHDVVLWGHDPKHIATLQRDRCNVAFLPDVPFPDSLHLESDLATALAASRNILIVVPSHVFG 89
Cdd:COG0240    5 VLGAGSWGTALAKVLARNGHEVTLWGRDPEVAEEINETRENPRYLPGVKLPENLRATSDLEEALAGADLVLLAVPSQALR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  90 EVLRQIKPLMRPDARIVWATKGLEAETGRLLQDVAREALGDDIPLAVISGPTFAKELAAGLPTAISLASTDQAFSDDLQQ 169
Cdd:COG0240   85 EVLEQLAPLLPPGAPVVSATKGIEPGTGLLMSEVIAEELPGALRIAVLSGPSFAEEVARGLPTAVVVASEDEEVAERLQE 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210 170 LLHCgKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMSRLGAALGADPATFMGMAGLGDL 249
Cdd:COG0240  165 LLST-PYFRVYTSDDVIGVELGGALKNVIAIAAGIADGLGLGDNARAALITRGLAEMTRLGVALGARPETFMGLAGLGDL 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210 250 VLTCTDNQSRNRRFGMMLGQGSDVKSAQEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLG 329
Cdd:COG0240  244 VLTCTSDLSRNRRFGLALGKGKSLEEALAEMGMVAEGVYTAKAVYELAEKLGVEMPITEAVYAVLYEGKSPREAVEALMA 323


                 ....
gi 498112210 330 RARK 333
Cdd:COG0240  324 RPLK 327
PRK14618 PRK14618
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional
 10-335 9.42e-84

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 237770 [Multi-domain]  Cd Length: 328  Bit Score: 256.72  E-value: 9.42e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  10 VIGAGSYGTALAITLARNGHDVVLWGHDPKHIATLQRDRCNVAFLPDVPFPDSLHLESDLATALAASRNILIVVPSHVFG 89
Cdd:PRK14618   9 VLGAGAWGTALAVLAASKGVPVRLWARRPEFAAALAAERENREYLPGVALPAELYPTADPEEALAGADFAVVAVPSKALR 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  90 EVLRQIKPlmrpDARIVWATKGLEAETGRLLQDVAREALGDDIPLAVISGPTFAKELAAGLPTAISLASTDQAFSDDLQQ 169
Cdd:PRK14618  89 ETLAGLPR----ALGYVSCAKGLAPDGGRLSELARVLEFLTQARVAVLSGPNHAEEIARFLPAATVVASPEPGLARRVQA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210 170 LLhCGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMSRLGAALGADPATFMGMAGLGDL 249
Cdd:PRK14618 165 AF-SGPSFRVYTSRDRVGVELGGALKNVIALAAGMVDGLKLGDNAKAALITRGLREMVRFGVALGAEEATFYGLSGLGDL 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210 250 VLTCTDNQSRNRRFGMMLGQGSDVKSAQEKiGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLG 329
Cdd:PRK14618 244 IATATSPHSRNRAAGEAIVRGVDREHLEAG-GKVVEGLYTVKALDAWAKAHGHDLPIVEAVARVARGGWDPLAGLRSLMG 322


                 ....*.
gi 498112210 330 RARKDE 335
Cdd:PRK14618 323 REAKEE 328
PRK12439 PRK12439
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional
 9-335 5.10e-82

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 171500 [Multi-domain]  Cd Length: 341  Bit Score: 252.40  E-value: 5.10e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210   9 IVIGAGSYGTALAITLARNGhDVVLWGHDPKHIATLQRDRCNVAFLP-DVPFPDSLHLESDLATALAASRNILIVVPSHV 87
Cdd:PRK12439  11 VVLGGGSWGTTVASICARRG-PTLQWVRSAETADDINDNHRNSRYLGnDVVLSDTLRATTDFAEAANCADVVVMGVPSHG 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  88 FGEVLRQIKPLMRPDARIVWATKGLEAETGRLLQDVAREALGDDiPLAVISGPTFAKELAAGLPTAISLASTDQAFSDDL 167
Cdd:PRK12439  90 FRGVLTELAKELRPWVPVVSLVKGLEQGTNMRMSQIIEEVLPGH-PAGILAGPNIAREVAEGYAAAAVLAMPDQHLATRL 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210 168 QQLLHCgKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMSRLGAALGADPATFMGMAGLG 247
Cdd:PRK12439 169 SPLFRT-RRFRVYTTDDVVGVEMAGALKNVFAIAVGMGYSLGIGENTRAMVIARALREMTKLGVAMGGNPETFAGLAGMG 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210 248 DLVLTCTDNQSRNRRFGMMLGQGSDVKSAQEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTL 327
Cdd:PRK12439 248 DLIVTCTSQRSRNRHVGEQLGAGKPIDEIIASMNQVAEGVKAASVVMEFADEYGLNMPIAREVDAVINHGSTVEQAYRGL 327


                 ....*...
gi 498112210 328 LGRARKDE 335
Cdd:PRK12439 328 IAEVPGHE 335
PRK14619 PRK14619
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional
 10-335 1.25e-81

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 237771 [Multi-domain]  Cd Length: 308  Bit Score: 250.29  E-value: 1.25e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  10 VIGAGSYGTALAITLARNGHDVVLWghdpkhiatlqrdrcnvaflpdvpfpdSLHLESDLATALAASRNILIVVPSHVFG 89
Cdd:PRK14619   9 ILGAGAWGSTLAGLASANGHRVRVW---------------------------SRRSGLSLAAVLADADVIVSAVSMKGVR 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  90 EVLRQIKPL-MRPDARIVWATKGLEAETGRLLQDVAREALGDDiPLAVISGPTFAKELAAGLPTAISLASTDQAFSDDLQ 168
Cdd:PRK14619  62 PVAEQVQALnLPPETIIVTATKGLDPETTRTPSQIWQAAFPNH-PVVVLSGPNLSKEIQQGLPAATVVASRDLAAAETVQ 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210 169 QLLhCGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMSRLGAALGADPATFMGMAGLGD 248
Cdd:PRK14619 141 QIF-SSERFRVYTNSDPLGTELGGTLKNVIAIAAGVCDGLQLGTNAKAALVTRALPEMIRVGTHLGAQTETFYGLSGLGD 219

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210 249 LVLTCTDNQSRNRRFGMMLGQGSDVKSAQEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLyCGKNAREAALT-L 327
Cdd:PRK14619 220 LLATCTSPLSRNYQVGYGLAQGKSLEQILAELEGTAEGVNTANVLVQLAQQQNIAVPITEQVYRLL-QGEITPQQALEeL 298


                 ....*...
gi 498112210 328 LGRARKDE 335
Cdd:PRK14619 299 MERDLKPE 306
NAD_Gly3P_dh_C pfam07479
NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent ...
 184-323 2.29e-77

NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase (GPDH) catalyzes the interconversion of dihydroxyacetone phosphate and L-glycerol-3-phosphate. This family represents the C-terminal substrate-binding domain.


Pssm-ID: 462178 [Multi-domain]  Cd Length: 142  Bit Score: 233.43  E-value: 2.29e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  184 DFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMSRLGAALGADPATFMGMAGLGDLVLTCTDNQSRNRRF 263
Cdd:pfam07479   1 DVIGVELGGALKNVIAIAAGIADGLGLGDNAKAALITRGLAEMIRLGKALGAKPETFFGLAGLGDLIVTCTSGLSRNRRF 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  264 GMMLGQGSDVKSAQEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREA 323
Cdd:pfam07479  81 GEALGKGKSLEEAEKELGQVAEGVYTAKAVYELAKKLGVEMPIFEAVYRILYEGKSPEEA 140
NAD_Gly3P_dh_N pfam01210
NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; NAD-dependent ...
 10-163 1.75e-72

NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase (GPDH) catalyzes the interconversion of dihydroxyacetone phosphate and L-glycerol-3-phosphate. This family represents the N-terminal NAD-binding domain.


Pssm-ID: 395967 [Multi-domain]  Cd Length: 158  Bit Score: 221.68  E-value: 1.75e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210   10 VIGAGSYGTALAITLARNGHDVVLWGHDPKHIATLQRDRCNVAFLPDVPFPDSLHLESDLATALAASRNILIVVPSHVFG 89
Cdd:pfam01210   4 VLGAGSWGTALAKVLADNGHEVRLWGRDEELIEEINTTHENVRYLPGIKLPENLKATTDLAEALKGADIIVIVVPSQALR 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 498112210   90 EVLRQIKPLMRPDARIVWATKGLEAETGRLLQDVAREALGDDIPLAVISGPTFAKELAAGLPTAISLASTDQAF 163
Cdd:pfam01210  84 EVLKQLKGLLKPDAILVSLSKGIEPGTLKLLSEVIEEELGIQPPIAVLSGPSHAEEVAQGLPTATVIASKDEEA 157
PRK14620 PRK14620
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional
 10-315 2.83e-68

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 173083 [Multi-domain]  Cd Length: 326  Bit Score: 216.62  E-value: 2.83e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  10 VIGAGSYGTALAITLARNGHDVVLWGHDPKHIATLQRDRCNVAFLPDVPFPDSLHLESDLATALAASRNILIV-VPSHVF 88
Cdd:PRK14620   5 ILGAGSFGTAIAIALSSKKISVNLWGRNHTTFESINTKRKNLKYLPTCHLPDNISVKSAIDEVLSDNATCIILaVPTQQL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  89 GEVLRQIKPL-MRPDARIVWATKGLEAETGRLLQDVAREALGDDiPLAVISGPTFAKELAAGLPTAISLASTDQAFSDDL 167
Cdd:PRK14620  85 RTICQQLQDChLKKNTPILICSKGIEKSSLKFPSEIVNEILPNN-PIAILSGPSFAKEIAEKLPCSIVLAGQNETLGSSL 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210 168 QQLLHcGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMSRLGAA--LGADPATFMGMAG 245
Cdd:PRK14620 164 ISKLS-NENLKIIYSQDIIGVQIGAALKNIIAIACGIVLGKNLGNNAHAAVITKGMNEIKTLYSAknGSIDLNTLIGPSC 242

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210 246 LGDLVLTCTDNQSRNRRFGMMLGQGSDVKSAQEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLY 315
Cdd:PRK14620 243 LGDLILTCTTLHSRNMSFGFKIGNGFNINQILSEGKSVIEGFSTVKPLISLAKKLNIELPICESIYNLLY 312
glycerol3P_DH TIGR03376
glycerol-3-phosphate dehydrogenase (NAD(+)); Members of this protein family are the eukaryotic ...
 10-317 4.01e-55

glycerol-3-phosphate dehydrogenase (NAD(+)); Members of this protein family are the eukaryotic enzyme, glycerol-3-phosphate dehydrogenase (NAD(+)) (EC 1.1.1.8). Enzymatic activity for 1.1.1.8 is defined as sn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADH. Note the very similar reactions of enzymes defined as EC 1.1.1.94 and 1.1.99.5, assigned to families of proteins in the bacteria.


Pssm-ID: 274551 [Multi-domain]  Cd Length: 342  Bit Score: 183.31  E-value: 4.01e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210   10 VIGAGSYGTALAITLARNG--------HDVVLWGHDPKHIAT-----LQRDRCNVAFLPDVPFPDSLHLESDLATALAAS 76
Cdd:TIGR03376   4 VVGSGNWGTAIAKIVAENAralpelfeESVRMWVFEEEIEGRnlteiINTTHENVKYLPGIKLPANLVAVPDLVEAAKGA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210   77 RNILIVVPSHVFGEVLRQIKPLMRPDARIVWATKGLE--AETGRLLQDVAREALGddIPLAVISGPTFAKELAAGLPTAI 154
Cdd:TIGR03376  84 DILVFVIPHQFLEGICKQLKGHVKPNARAISCIKGLEvsKDGVKLLSDIIEEELG--IPCGVLSGANLANEVAKEKFSET 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  155 SLASTDQAFSDD----LQQLLHcGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMSRLG 230
Cdd:TIGR03376 162 TVGYRDPADFDVdarvLKALFH-RPYFRVNVVDDVAGVEIAGALKNVVAIAAGFVDGLGWGDNAKAAVMRRGLLEMIKFA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  231 AALG--ADPATFMGMAGLGDLVLTCTDnqSRNRRFGMMLGQGSdvKSAQE-----KIGQVVEGYRNTKEVRELAHRFGV- 302
Cdd:TIGR03376 241 RMFFptGEVTFTFESCGVADLITTCLG--GRNFKVGRAFAKTG--KSLEElekelLNGQSLQGVATAKEVHELLKNKNKd 316

                         330
                  ....*....|....*.
gi 498112210  303 -EMPITEEIYQVLYCG 317
Cdd:TIGR03376 317 dEFPLFEAVYQILYEG 332
PTZ00345 PTZ00345
glycerol-3-phosphate dehydrogenase; Provisional
 10-322 3.31e-38

glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 240373 [Multi-domain]  Cd Length: 365  Bit Score: 139.39  E-value: 3.31e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  10 VIGAGSYGTALAITLARNGH-------DVVLWGHDP-----KHIATLQRDRCNVAFLPDVPFPDSLHLESDLATALAASr 77
Cdd:PTZ00345  16 VIGSGNWGSAISKVVGENTQrnyifhnEVRMWVLEEivegeKLSDIINTKHENVKYLPGIKLPDNIVAVSDLKEAVEDA- 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  78 NILI-VVPSHVFGEVLRQIKPL--MRPDARIVWATKGLEAETGR--LLQDVAREALGddIPLAVISGPTFAKELAAGLPT 152
Cdd:PTZ00345  95 DLLIfVIPHQFLESVLSQIKENnnLKKHARAISLTKGIIVENGKpvLCSDVIEEELG--IPCCALSGANVANDVAREEFS 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210 153 AISLASTDQAFSDDLQQLLHCgKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMSRLGAA 232
Cdd:PTZ00345 173 EATIGCEDKDDALIWQRLFDR-PYFKINCVPDVIGVEVCGALKNIIALAAGFCDGLGLGTNTKSAIIRIGLEEMKLFGKI 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210 233 L--GADPATFMGMAGLGDLVLTCTDnqSRNRRFGMMLGQGSDVKSaQEKI------GQVVEGYRNTKEVREL--AHRFGV 302
Cdd:PTZ00345 252 FfpNVMDETFFESCGLADLITTCLG--GRNVRCAAEFAKRNGKKS-WEEIeaellnGQKLQGTVTLKEVYEVleSHDLKK 328

                        330       340
                 ....*....|....*....|
gi 498112210 303 EMPITEEIYQVLYCGKNARE 322
Cdd:PTZ00345 329 EFPLFTVTYKIAFEGADPSS 348
GPD_NAD_C_bact pfam20618
Bacterial GPD, NAD-dependent C-terminal; This is the C-terminal domain of NAD-dependent ...
 244-310 1.61e-27

Bacterial GPD, NAD-dependent C-terminal; This is the C-terminal domain of NAD-dependent glycerol-3-phosphate dehydrogenase (GPD) from bacteria and archaea. GPD catalyzes the reversible reduction of dihydroxyacetone phosphate to glycerol-3-phosphate.


Pssm-ID: 466767 [Multi-domain]  Cd Length: 66  Bit Score: 102.57  E-value: 1.61e-27
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 498112210  244 AGLGDLVLTCTDNQSRNRRFGMMLGQGsdVKSAQEKIGQVVEGYRNTKEVRE-LAHRFGVEMPITEEI 310
Cdd:pfam20618   1 AGLGDLVLTCTSDLSRNRTFGLLLGKG--MTLAEAGNGQVAEGVRTAKAVAAiLARAHNVEMPILEAV 66
ApbA pfam02558
Ketopantoate reductase PanE/ApbA; This is a family of 2-dehydropantoate 2-reductases also ...
 10-142 6.04e-09

Ketopantoate reductase PanE/ApbA; This is a family of 2-dehydropantoate 2-reductases also known as ketopantoate reductases, EC:1.1.1.169. The reaction catalyzed by this enzyme is: (R)-pantoate + NADP(+) <=> 2-dehydropantoate + NADPH. AbpA catalyzes the NADPH reduction of ketopantoic acid to pantoic acid in the alternative pyrimidine biosynthetic (APB) pathway. ApbA and PanE are allelic. ApbA, the ketopantoate reductase enzyme is required for the synthesis of thiamine via the APB biosynthetic pathway.


Pssm-ID: 426831 [Multi-domain]  Cd Length: 147  Bit Score: 54.16  E-value: 6.04e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210   10 VIGAGSYGTALAITLARNGHDVVLWGHDPKHIA------TLQRDRCNVAFLPDVPFPDSLHLESdlatalaaSRNILIVV 83
Cdd:pfam02558   3 ILGAGAIGSLLGARLAKAGHDVTLILRGAELAAikknglRLTSPGGERIVPPPAVTSASESLGP--------IDLVIVTV 74

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 498112210   84 PSHVFGEVLRQIKPLMRPDARIVWATKGLEAEtgrllqDVAREALGDDiplAVISGPTF 142
Cdd:pfam02558  75 KAYQTEEALEDIAPLLGPNTVVLLLQNGLGHE------EVLREAVPRE---RVLGGVTT 124
PanE COG1893
Ketopantoate reductase [Coenzyme transport and metabolism]; Ketopantoate reductase is part of ...
 10-131 2.40e-07

Ketopantoate reductase [Coenzyme transport and metabolism]; Ketopantoate reductase is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


Pssm-ID: 441497 [Multi-domain]  Cd Length: 305  Bit Score: 51.40  E-value: 2.40e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  10 VIGAGSYGTALAITLARNGHDVVLWGHdPKHIATLQRDRCNVAFLPDVPFPDSLHLESDLAtALAASRNILIVVPSHVFG 89
Cdd:COG1893    5 ILGAGAIGGLLGARLARAGHDVTLVAR-GAHAEALRENGLRLESPDGDRTTVPVPAVTDPE-ELGPADLVLVAVKAYDLE 82

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 498112210  90 EVLRQIKPLMRPDARIVWATKGLEAEtgrllqDVAREALGDD 131
Cdd:COG1893   83 AAAEALAPLLGPDTVVLSLQNGLGHE------ERLAEALGAE 118
PRK06522 PRK06522
2-dehydropantoate 2-reductase; Reviewed
 10-106 7.98e-06

2-dehydropantoate 2-reductase; Reviewed


Pssm-ID: 235821 [Multi-domain]  Cd Length: 304  Bit Score: 46.77  E-value: 7.98e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  10 VIGAGSYGTALAITLARNGHDVVLWGHDPKHIATLQRDRCNV----AFLPDVPFPDSLHL-ESDLatalaasrnILIVVP 84
Cdd:PRK06522   5 ILGAGAIGGLFGAALAQAGHDVTLVARRGAHLDALNENGLRLedgeITVPVLAADDPAELgPQDL---------VILAVK 75

                         90       100
                 ....*....|....*....|..
gi 498112210  85 SHVFGEVLRQIKPLMRPDARIV 106
Cdd:PRK06522  76 AYQLPAALPSLAPLLGPDTPVL 97
Ugd COG1004
UDP-glucose 6-dehydrogenase [Cell wall/membrane/envelope biogenesis];
10-148 1.07e-05

UDP-glucose 6-dehydrogenase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440628 [Multi-domain]  Cd Length: 436  Bit Score: 46.94  E-value: 1.07e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  10 VIGAGSYGTALAITLARNGHDVVLWGHDPKHIATLQRDRcnvaflpdVPF--P------------DSLHLESDLATALAA 75
Cdd:COG1004    5 VIGTGYVGLVTAACLAELGHEVTCVDIDEEKIEALNAGE--------IPIyePgleelvarnvaaGRLRFTTDLAEAVAE 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  76 SRNILIVVP-----------SHVFgEVLRQIKPLMRPDARIVwaTK-----GleaeTGRLLQDVAREAL-GDDIPLAVIS 138
Cdd:COG1004   77 ADVVFIAVGtpsdedgsadlSYVL-AAARSIGEALKGYKVVV--TKstvpvG----TADRVRAIIAEELrGAGVDFDVVS 149

                        170
                 ....*....|
gi 498112210 139 GPTFAKELAA 148
Cdd:COG1004  150 NPEFLREGSA 159
PRK08655 PRK08655
prephenate dehydrogenase; Provisional
 9-102 3.11e-05

prephenate dehydrogenase; Provisional


Pssm-ID: 236326 [Multi-domain]  Cd Length: 437  Bit Score: 45.36  E-value: 3.11e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210   9 IVIGAGSYGTALAITLARNGHDVVLWGHDPKHIATLQRdRCNVAFLPDvpfpdslhlesdlATALAASRNILIV-VPSHV 87
Cdd:PRK08655   5 IIGGTGGLGKWFARFLKEKGFEVIVTGRDPKKGKEVAK-ELGVEYAND-------------NIDAAKDADIVIIsVPINV 70

                         90
                 ....*....|....*
gi 498112210  88 FGEVLRQIKPLMRPD 102
Cdd:PRK08655  71 TEDVIKEVAPHVKEG 85
COG5495 COG5495
Predicted oxidoreductase, contains short-chain dehydrogenase (SDR) and DUF2520 domains ...
 10-106 6.85e-05

Predicted oxidoreductase, contains short-chain dehydrogenase (SDR) and DUF2520 domains [General function prediction only];


Pssm-ID: 444246 [Multi-domain]  Cd Length: 286  Bit Score: 44.03  E-value: 6.85e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  10 VIGAGSYGTALAITLARNGHDVV-LWGHDPKHIATLqrdrcnVAFLPDVPF--PDSLHLESDLatalaasrnILIVVPSH 86
Cdd:COG5495    8 IIGAGRVGTALAAALRAAGHEVVgVYSRSPASAERA------AALLGAVPAldLEELAAEADL---------VLLAVPDD 72

                         90       100
                 ....*....|....*....|..
gi 498112210  87 VFGEVLRQIK--PLMRPDARIV 106
Cdd:COG5495   73 AIAEVAAGLAaaGALRPGQLVV 94
PRK06129 PRK06129
3-hydroxyacyl-CoA dehydrogenase; Validated
 6-114 9.44e-05

3-hydroxyacyl-CoA dehydrogenase; Validated


Pssm-ID: 235706 [Multi-domain]  Cd Length: 308  Bit Score: 43.49  E-value: 9.44e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210   6 ASMIVIGAGSYGTALAITLARNGHDVVLWGHDPkhiATLQRDRCNVA-FLPDVPFPDSLHLES------------DLATA 72
Cdd:PRK06129   3 GSVAIIGAGLIGRAWAIVFARAGHEVRLWDADP---AAAAAAPAYIAgRLEDLAAFDLLDGEApdavlarirvtdSLADA 79

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 498112210  73 LAASRNILIVVPSHVFG--EVLRQIKPLMRPDARIVWATKGLEA 114
Cdd:PRK06129  80 VADADYVQESAPENLELkrALFAELDALAPPHAILASSTSALLA 123
PRK08229 PRK08229
2-dehydropantoate 2-reductase; Provisional
 5-135 1.76e-04

2-dehydropantoate 2-reductase; Provisional


Pssm-ID: 236193 [Multi-domain]  Cd Length: 341  Bit Score: 42.68  E-value: 1.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210   5 NASMIVIGAGSYGTALAITLARNGHDVVLWGHDP------KHIATLQRDRCNVAFLPdvpfPDSLHLESDLAtALAASRN 78
Cdd:PRK08229   2 MARICVLGAGSIGCYLGGRLAAAGADVTLIGRARigdelrAHGLTLTDYRGRDVRVP----PSAIAFSTDPA-ALATADL 76

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 498112210  79 ILIVVPSHVFGEVLRQIKPLMRPDARIVWATKGLEAEtgrllqDVAREALGDDIPLA 135
Cdd:PRK08229  77 VLVTVKSAATADAAAALAGHARPGAVVVSFQNGVRNA------DVLRAALPGATVLA 127
GIDA pfam01134
Glucose inhibited division protein A;
9-53 1.78e-04

Glucose inhibited division protein A;


Pssm-ID: 250388 [Multi-domain]  Cd Length: 391  Bit Score: 42.92  E-value: 1.78e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 498112210    9 IVIGAGSYGTALAITLARNGHDVVLWGHDPKHIATLQrdrCNVAF 53
Cdd:pfam01134   3 IVIGGGHAGCEAALAAARMGAKVLLITHNTDTIAELS---CNPSI 44
ProC COG0345
Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; ...
 10-106 3.06e-04

Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Pyrroline-5-carboxylate reductase is part of the Pathway/BioSystem: Proline biosynthesis


Pssm-ID: 440114 [Multi-domain]  Cd Length: 267  Bit Score: 41.97  E-value: 3.06e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  10 VIGAGSYGTALAITLARNG---HDVVLWGHDPKHIATLQRdRCNVaflpdvpfpdslHLESDLATALAASRNILIVVPSH 86
Cdd:COG0345    7 FIGAGNMGSAIIKGLLKSGvppEDIIVSDRSPERLEALAE-RYGV------------RVTTDNAEAAAQADVVVLAVKPQ 73

                         90       100
                 ....*....|....*....|
gi 498112210  87 VFGEVLRQIKPLMRPDARIV 106
Cdd:COG0345   74 DLAEVLEELAPLLDPDKLVI 93
NDP-sugDHase TIGR03026
nucleotide sugar dehydrogenase; Enzymes in this family catalyze the NAD-dependent ...
 10-106 4.49e-04

nucleotide sugar dehydrogenase; Enzymes in this family catalyze the NAD-dependent alcohol-to-acid oxidation of nucleotide-linked sugars. Examples include UDP-glucose 6-dehydrogenase (1.1.1.22), GDP-mannose 6-dehydrogenase (1.1.1.132), UDP-N-acetylglucosamine 6-dehydrogenase (1.1.1.136), UDP-N-acetyl-D-galactosaminuronic acid dehydrogenase, and UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase. These enzymes are most often involved in the biosynthesis of polysaccharides and are often found in operons devoted to that purpose. All of these enzymes contain three Pfam domains, pfam03721, pfam00984, and pfam03720 for the N-terminal, central, and C-terminal regions respectively.


Pssm-ID: 274399 [Multi-domain]  Cd Length: 409  Bit Score: 41.83  E-value: 4.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210   10 VIGAGSYGTALAITLARNGHDVVLWGHDPKHIATLQRDRCNV------AFLPDVPFPDSLHLESDLATALAASRNILIVV 83
Cdd:TIGR03026   5 VIGLGYVGLPLAALLADLGHDVTGVDIDQEKVDKLNKGKSPIyepgldELLAKALKAGRLRATTDYEEAIRDADVIIICV 84

                          90       100       110
                  ....*....|....*....|....*....|....
gi 498112210   84 P-----------SHVFgEVLRQIKPLMRPDARIV 106
Cdd:TIGR03026  85 PtplkedgspdlSYVE-SAAETIAKHLRKGATVV 117
TrkA COG0569
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ...
 9-51 2.14e-03

Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440335 [Multi-domain]  Cd Length: 296  Bit Score: 39.28  E-value: 2.14e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 498112210   9 IVIGAGSYGTALAITLARNGHDVVLWGHDPKHIATLQRDRCNV 51
Cdd:COG0569   99 IIIGAGRVGRSLARELEEEGHDVVVIDKDPERVERLAEEDVLV 141
PRK09599 PRK09599
NADP-dependent phosphogluconate dehydrogenase;
10-102 3.43e-03

NADP-dependent phosphogluconate dehydrogenase;


Pssm-ID: 236582 [Multi-domain]  Cd Length: 301  Bit Score: 38.58  E-value: 3.43e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498112210  10 VIGAGSYGTALAITLARNGHDVVLWGHDPKHIATLQRDRCNVAflpdvpfpDSLhleSDLATALAASRNILIVVPS-HVF 88
Cdd:PRK09599   5 MIGLGRMGGNMARRLLRGGHEVVGYDRNPEAVEALAEEGATGA--------DSL---EELVAKLPAPRVVWLMVPAgEIT 73

                         90
                 ....*....|....
gi 498112210  89 GEVLRQIKPLMRPD 102
Cdd:PRK09599  74 DATIDELAPLLSPG 87
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
9-33 9.33e-03

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 37.58  E-value: 9.33e-03
                         10        20
                 ....*....|....*....|....*
gi 498112210   9 IVIGAGSYGTALAITLARNGHDVVL 33
Cdd:COG0665    6 VVIGGGIAGLSTAYHLARRGLDVTV 30
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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