|
Name |
Accession |
Description |
Interval |
E-value |
| PRK00145 |
PRK00145 |
putative inner membrane protein translocase component YidC; Provisional |
9-224 |
1.60e-84 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234665 [Multi-domain] Cd Length: 223 Bit Score: 250.81 E-value: 1.60e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 9 FVNFFDAIHGMIQSVISNPNYSYGIAIIIFTIVVKVILLPLTIKQTRSSVKLAEVQPKTAAIQEKYKNDPQRAQQEILKL 88
Cdd:PRK00145 9 FVQFFKFIHGFVSSVISNPNFSYGIAIILVTLIIRLLILPLNIKQTKSSLRMNEIQPEIKKLQAKYKNDPQKLQQEMMKL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 89 YKEENVSPMSGCLPLLIQYPIIIVLFYAFSTLN-YHGAGFLWIPNLNQPDPYFILPVLSGVSTYIMSKMLQPKTNANSSs 167
Cdd:PRK00145 89 YKEKGVNPLGGCLPLLIQWPILIALYYVFNNLTgINGVSFLWIKDLAKPDITWILPILSGATTYLSGYLMTKADSSQAG- 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 497984170 168 qampNMGMMNIVMAGMFTWMGFKMQSAIVIYWIINN--LIQLIQTLLLRPRKKNEELAT 224
Cdd:PRK00145 168 ----QMKTMNIGMSIFMGVMSWKFKSALVLYWVIGNliQIIQTYFIKKLELKKKVEAKA 222
|
|
| 5TM_YidC_Alb3 |
cd20070 |
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ... |
32-203 |
7.48e-73 |
|
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410994 [Multi-domain] Cd Length: 181 Bit Score: 219.56 E-value: 7.48e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 32 GIAIIIFTIVVKVILLPLTIKQTRSSVKLAEVQPKTAAIQEKYKNDPQRAQQEILKLYKEENVSPMSGCLPLLIQYPIII 111
Cdd:cd20070 1 GLAIILLTILIRLLLLPLTLKQYKSMKKMQELQPKIKEIQEKYKDDKQKLQQEMMKLYKEHGVNPLGGCLPLLIQMPIFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 112 VLFYAF-STLNYHGAGFLW-IPNLNQPDPYFILPVLSGVSTYIMSKMLQPKTnanssSQAMPNMGMMNIVMAGMFTWMGF 189
Cdd:cd20070 81 ALYQVLrNSIELRGAPFLWwILDLSAPDPYYILPILMGVTMFLQQKLTPTPT-----DDQAPQQKMMMYFMPVMFTFIFL 155
|
170
....*....|....
gi 497984170 190 KMQSAIVIYWIINN 203
Cdd:cd20070 156 SFPSGLVLYWLVSN 169
|
|
| YidC |
COG0706 |
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis]; |
4-203 |
1.52e-72 |
|
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440470 [Multi-domain] Cd Length: 212 Bit Score: 219.99 E-value: 1.52e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 4 FFSVYFVNFFDAIHGMIQSvisnpnysYGIAIIIFTIVVKVILLPLTIKQTRSSVKLAEVQPKTAAIQEKYKNDPQRAQQ 83
Cdd:COG0706 8 FIAKPLFWLLNFLHSLVGN--------WGLAIILLTLIVRLLLFPLTVKQYKSMAKMQELQPELKEIQEKYKDDPQKLQQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 84 EILKLYKEENVSPMSGCLPLLIQYPIIIVLFYAF-STLNYHGAGFLWIPNLNQPDPYFI-LPVLSGVSTYIMSKMlqpkt 161
Cdd:COG0706 80 EMMKLYKEEGVNPLGGCLPMLIQMPIFIALYRVLrNSIELRHAPFLGIPDLSAPDPYYIfLPILMGVTMFLQQKL----- 154
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 497984170 162 naNSSSQAMPNMGMMNIVMAGMFTWMGFKMQSAIVIYWIINN 203
Cdd:COG0706 155 --NPAPAQDPQQKKMMYIMPLMFLFFFLSFPAGLVLYWVVSN 194
|
|
| yidC_oxa1_cterm |
TIGR03592 |
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ... |
30-203 |
1.48e-70 |
|
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274665 [Multi-domain] Cd Length: 179 Bit Score: 213.88 E-value: 1.48e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 30 SYGIAIIIFTIVVKVILLPLTIKQTRSSVKLAEVQPKTAAIQEKYKNDPQRAQQEILKLYKEENVSPMSGCLPLLIQYPI 109
Cdd:TIGR03592 1 NWGLAIILLTIIVRLILLPLTLKQYKSMRKMQELQPKLKEIQEKYKEDPQKLQQEMMKLYKEEGVNPLGGCLPLLIQMPI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 110 IIVLFYAFS-TLNYHGAGFLWIPNLNQPDPYFILPVLSGVSTYIMSKMlQPKTNANSSSQAmpnmgMMNIVMAGMFTWMG 188
Cdd:TIGR03592 81 FIALYQVLLrSIELRHAPFLWIIDLSSPDPYYILPILMGVTMFLQQKL-SPKGPPDPAQQK-----MMMYFMPLMFLFFF 154
|
170
....*....|....*
gi 497984170 189 FKMQSAIVIYWIINN 203
Cdd:TIGR03592 155 LSFPAGLVLYWVVSN 169
|
|
| 60KD_IMP |
pfam02096 |
60Kd inner membrane protein; |
31-203 |
6.36e-70 |
|
60Kd inner membrane protein;
Pssm-ID: 460443 [Multi-domain] Cd Length: 187 Bit Score: 212.33 E-value: 6.36e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 31 YGIAIIIFTIVVKVILLPLTIKQTRSSVKLAEVQPKTAAIQEKYKNDPQRAQQEILKLYKEENVSPMSGCLPLLIQYPII 110
Cdd:pfam02096 1 YGLAIILLTILIKLILFPLTYKQYKSMAKMQELQPEMKEIQEKYKDDRQKLQQEMMKLYKKEGVNPLGGCLPMLIQMPIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 111 IVLFYAFSTLN--YHGAGFLWIPNLNQPDP-----YFILPVLSGVSTYIMSKMLQPKTNansssQAMPNMGMMNIVMAGM 183
Cdd:pfam02096 81 IALYRVLRNSIelRHAPFFLWIADLSAPDPisilhYYILPILMGVTMFLQQKLTPAPQD-----QPPQMKMMMLYFMPLM 155
|
170 180
....*....|....*....|
gi 497984170 184 FTWMGFKMQSAIVIYWIINN 203
Cdd:pfam02096 156 FLFFFLNFPAGLVLYWVVSN 175
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK00145 |
PRK00145 |
putative inner membrane protein translocase component YidC; Provisional |
9-224 |
1.60e-84 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234665 [Multi-domain] Cd Length: 223 Bit Score: 250.81 E-value: 1.60e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 9 FVNFFDAIHGMIQSVISNPNYSYGIAIIIFTIVVKVILLPLTIKQTRSSVKLAEVQPKTAAIQEKYKNDPQRAQQEILKL 88
Cdd:PRK00145 9 FVQFFKFIHGFVSSVISNPNFSYGIAIILVTLIIRLLILPLNIKQTKSSLRMNEIQPEIKKLQAKYKNDPQKLQQEMMKL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 89 YKEENVSPMSGCLPLLIQYPIIIVLFYAFSTLN-YHGAGFLWIPNLNQPDPYFILPVLSGVSTYIMSKMLQPKTNANSSs 167
Cdd:PRK00145 89 YKEKGVNPLGGCLPLLIQWPILIALYYVFNNLTgINGVSFLWIKDLAKPDITWILPILSGATTYLSGYLMTKADSSQAG- 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 497984170 168 qampNMGMMNIVMAGMFTWMGFKMQSAIVIYWIINN--LIQLIQTLLLRPRKKNEELAT 224
Cdd:PRK00145 168 ----QMKTMNIGMSIFMGVMSWKFKSALVLYWVIGNliQIIQTYFIKKLELKKKVEAKA 222
|
|
| 5TM_YidC_Alb3 |
cd20070 |
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ... |
32-203 |
7.48e-73 |
|
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410994 [Multi-domain] Cd Length: 181 Bit Score: 219.56 E-value: 7.48e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 32 GIAIIIFTIVVKVILLPLTIKQTRSSVKLAEVQPKTAAIQEKYKNDPQRAQQEILKLYKEENVSPMSGCLPLLIQYPIII 111
Cdd:cd20070 1 GLAIILLTILIRLLLLPLTLKQYKSMKKMQELQPKIKEIQEKYKDDKQKLQQEMMKLYKEHGVNPLGGCLPLLIQMPIFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 112 VLFYAF-STLNYHGAGFLW-IPNLNQPDPYFILPVLSGVSTYIMSKMLQPKTnanssSQAMPNMGMMNIVMAGMFTWMGF 189
Cdd:cd20070 81 ALYQVLrNSIELRGAPFLWwILDLSAPDPYYILPILMGVTMFLQQKLTPTPT-----DDQAPQQKMMMYFMPVMFTFIFL 155
|
170
....*....|....
gi 497984170 190 KMQSAIVIYWIINN 203
Cdd:cd20070 156 SFPSGLVLYWLVSN 169
|
|
| YidC |
COG0706 |
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis]; |
4-203 |
1.52e-72 |
|
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440470 [Multi-domain] Cd Length: 212 Bit Score: 219.99 E-value: 1.52e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 4 FFSVYFVNFFDAIHGMIQSvisnpnysYGIAIIIFTIVVKVILLPLTIKQTRSSVKLAEVQPKTAAIQEKYKNDPQRAQQ 83
Cdd:COG0706 8 FIAKPLFWLLNFLHSLVGN--------WGLAIILLTLIVRLLLFPLTVKQYKSMAKMQELQPELKEIQEKYKDDPQKLQQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 84 EILKLYKEENVSPMSGCLPLLIQYPIIIVLFYAF-STLNYHGAGFLWIPNLNQPDPYFI-LPVLSGVSTYIMSKMlqpkt 161
Cdd:COG0706 80 EMMKLYKEEGVNPLGGCLPMLIQMPIFIALYRVLrNSIELRHAPFLGIPDLSAPDPYYIfLPILMGVTMFLQQKL----- 154
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 497984170 162 naNSSSQAMPNMGMMNIVMAGMFTWMGFKMQSAIVIYWIINN 203
Cdd:COG0706 155 --NPAPAQDPQQKKMMYIMPLMFLFFFLSFPAGLVLYWVVSN 194
|
|
| yidC_oxa1_cterm |
TIGR03592 |
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ... |
30-203 |
1.48e-70 |
|
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274665 [Multi-domain] Cd Length: 179 Bit Score: 213.88 E-value: 1.48e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 30 SYGIAIIIFTIVVKVILLPLTIKQTRSSVKLAEVQPKTAAIQEKYKNDPQRAQQEILKLYKEENVSPMSGCLPLLIQYPI 109
Cdd:TIGR03592 1 NWGLAIILLTIIVRLILLPLTLKQYKSMRKMQELQPKLKEIQEKYKEDPQKLQQEMMKLYKEEGVNPLGGCLPLLIQMPI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 110 IIVLFYAFS-TLNYHGAGFLWIPNLNQPDPYFILPVLSGVSTYIMSKMlQPKTNANSSSQAmpnmgMMNIVMAGMFTWMG 188
Cdd:TIGR03592 81 FIALYQVLLrSIELRHAPFLWIIDLSSPDPYYILPILMGVTMFLQQKL-SPKGPPDPAQQK-----MMMYFMPLMFLFFF 154
|
170
....*....|....*
gi 497984170 189 FKMQSAIVIYWIINN 203
Cdd:TIGR03592 155 LSFPAGLVLYWVVSN 169
|
|
| 60KD_IMP |
pfam02096 |
60Kd inner membrane protein; |
31-203 |
6.36e-70 |
|
60Kd inner membrane protein;
Pssm-ID: 460443 [Multi-domain] Cd Length: 187 Bit Score: 212.33 E-value: 6.36e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 31 YGIAIIIFTIVVKVILLPLTIKQTRSSVKLAEVQPKTAAIQEKYKNDPQRAQQEILKLYKEENVSPMSGCLPLLIQYPII 110
Cdd:pfam02096 1 YGLAIILLTILIKLILFPLTYKQYKSMAKMQELQPEMKEIQEKYKDDRQKLQQEMMKLYKKEGVNPLGGCLPMLIQMPIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 111 IVLFYAFSTLN--YHGAGFLWIPNLNQPDP-----YFILPVLSGVSTYIMSKMLQPKTNansssQAMPNMGMMNIVMAGM 183
Cdd:pfam02096 81 IALYRVLRNSIelRHAPFFLWIADLSAPDPisilhYYILPILMGVTMFLQQKLTPAPQD-----QPPQMKMMMLYFMPLM 155
|
170 180
....*....|....*....|
gi 497984170 184 FTWMGFKMQSAIVIYWIINN 203
Cdd:pfam02096 156 FLFFFLNFPAGLVLYWVVSN 175
|
|
| PRK01318 |
PRK01318 |
membrane protein insertase; Provisional |
4-203 |
1.62e-52 |
|
membrane protein insertase; Provisional
Pssm-ID: 234942 [Multi-domain] Cd Length: 521 Bit Score: 177.37 E-value: 1.62e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 4 FFSVYFVNFFDAIHGMIqsvisnPNYsyGIAIIIFTIVVKVILLPLTIKQTRSSVKLAEVQPKTAAIQEKYKNDPQRAQQ 83
Cdd:PRK01318 304 FITKPLFWLLDFLHSFV------GNW--GWAIILLTIIVKLLLFPLTYKSYVSMAKMKVLQPKMQELKEKYKDDPQKMQQ 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 84 EILKLYKEENVSPMSGCLPLLIQYPIIIVLFYAFstLNY----HGAGFLWIPNLNQPDPYFIL-----PVLSGVSTYIMS 154
Cdd:PRK01318 376 EMMELYKKEKVNPLGGCLPILIQIPIFFALYKVL--LVSielrHAPFIGWIHDLSAPDPYFILhigllPILMGITMFLQQ 453
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 497984170 155 KMlqpktnaNSSSQAMPNMGMMNIvMAGMFTWMGFKMQSAIVIYWIINN 203
Cdd:PRK01318 454 KL-------NPTPTDPMQAKIMKF-MPLIFTFFFLSFPAGLVLYWIVNN 494
|
|
| 5TM_YidC_Oxa1_Alb3 |
cd19751 |
Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1 ... |
32-203 |
2.36e-41 |
|
Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1/Alb3 protein family of insertases facilitate the insertion, folding and assembly of proteins of the inner membranes of bacteria and mitochondria, and the thylakoid membrane of plastids. Members include bacterial YidC, mitochondrial Cox18 and Oxa1, and chloroplastic Alb3 and Alb4. Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Oxa1 and Cox18/Oxa2 mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Alb3 and Alb3-like proteins, including Alb4, are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410992 [Multi-domain] Cd Length: 189 Bit Score: 139.61 E-value: 2.36e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 32 GIAIIIFTIVVKVILLPLTIKQTRSSVKLAEVQPKTAAIQEKYKND------PQRAQQEILKLYKEENVSPMSGCLPLLI 105
Cdd:cd19751 1 GLSIIIVTILIRLALLPLTLKQQKSMRKMQVIRPEMEAIREKYKEKaskdkvQQEMQKEMLGLYKKHGVNPMAGCLPLFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 106 QYPIIIVLFYAF-STLNYHGAGFLWIPNLNQPDPYFILPVLSGVSTYIMSKMlqpktNANSSSQAMPNMGMMNI---VMA 181
Cdd:cd19751 81 QLPIFMAFYFAImRTEEIRYHTFLWFFDLGQPDYLYILPFVAGITTYFQFKM-----TMSHQQQMQMMQMQMKVmlyVMP 155
|
170 180
....*....|....*....|..
gi 497984170 182 GMFTWMGFKMQSAIVIYWIINN 203
Cdd:cd19751 156 VMIIIAGLSFPSALSLYWIISN 177
|
|
| 5TM_Oxa1-like |
cd20069 |
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar ... |
34-203 |
6.59e-39 |
|
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar proteins; This group is composed mostly of the mitochondrial members of the YidC/Oxa1/Alb3 protein family of insertases, including mitochondrial inner membrane proteins Oxa1, Oxa1-like (Oxa1L), cytochrome c oxidase assembly protein 18 (Cox18, also called Oxa2), and Arabidopsis thaliana mitochondrial ALBINO3-like protein 3 (ALB33). It also includes Arabidopsis thaliana chloroplastic ALBINO3-like protein 2 (ALB32). Members of this group mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Oxa1 and Cox18/Oxa2 are essential for the activity and assembly of cytochrome c oxidase, playing central roles in the translocation and export of the N-terminal and C-terminal parts, respectively, of the COX2 protein into the mitochondrial intermembrane space. ALB32 may be involved in the insertion of integral membrane proteins into the chloroplast thylakoid membranes. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410993 [Multi-domain] Cd Length: 201 Bit Score: 133.80 E-value: 6.59e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 34 AIIIFTIVVKVILLPLTIKQTRSSVKLAEVQPKTAAIQEKYK-----NDP---QRAQQEILKLYKEENVSPMSGCLPLLI 105
Cdd:cd20069 7 TIAATTVALRLLLLPLVIKSQRNAARMANLQPELQKLQEKLKearasGDQleaAEARKELKELMKKHNVNPLKSLLLPLV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 106 QYPIIIVLFYAFSTLNYHG------AGFLWIPNLNQPDPYFILPVLSGVSTYIMSKMlqpktNANSSSQAMPNMGMMNIV 179
Cdd:cd20069 87 QAPVFISFFFALRKMANLPvpsfktGGLLWFTDLTVPDPYYILPILTSLTFLATIEL-----GAETGTSGSPQSKTMKNV 161
|
170 180
....*....|....*....|....*..
gi 497984170 180 MAGM---FTWMGFKMQSAIVIYWIINN 203
Cdd:cd20069 162 FRGLpvlMIPFTANFPSAVFLYWITSN 188
|
|
| PRK01001 |
PRK01001 |
putative inner membrane protein translocase component YidC; Provisional |
30-200 |
5.43e-38 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234887 [Multi-domain] Cd Length: 795 Bit Score: 140.32 E-value: 5.43e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 30 SYGIAIIIFTIVVKVILLPLTIKQTRSSVKLAEVQPKTAAIQEKYKNDPQRAQQEILKLYKEENVSPMSGCLPLLIQYPI 109
Cdd:PRK01001 575 SWGISIILLTVFLKLLLYPLNAWSIRSMRRMQKLSPYIQEIQQKYKKEPKRAQMEIMALYKTNKVNPITGCLPLLIQLPF 654
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 110 IIVLFYAF-STLNYHGAGFL--WIPNLNQPDPYF--------------ILPVLSGVSTYIMSKM--LQPKTNANSSSQAM 170
Cdd:PRK01001 655 LIAMFDLLkSSFLLRGASFIpgWIDNLTAPDVLFswetpiwfignefhLLPILLGVVMFAQQKIssLKRKGPVTDQQRQQ 734
|
170 180 190
....*....|....*....|....*....|
gi 497984170 171 PNMGMMnivMAGMFTWMGFKMQSAIVIYWI 200
Cdd:PRK01001 735 EAMGTM---MALLFTFMFYNFPSGLNIYWL 761
|
|
| PRK01622 |
PRK01622 |
membrane protein insertase YidC; |
4-203 |
2.01e-36 |
|
membrane protein insertase YidC;
Pssm-ID: 179310 Cd Length: 256 Bit Score: 129.10 E-value: 2.01e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 4 FFSVYFVNFFDAihgMIQSVISNPNYSYGIAIIIFTIVVKVILLPLTIKQTRSSV----KLAEVQPKTAAIQEKYK--ND 77
Cdd:PRK01622 36 FFDHYFVYPFSF---LIQFVAHHIGGSYGIAIIIVTLIIRSLMIPLAVSQYKSQRgmqeKMAVMKPELDKIQAKLKvtKD 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 78 PQRA---QQEILKLYKEENVSPMS-GCLPLLIQYPIIIVLFYAF-STLNYHGAGFLWIpNLNQPDpyFILPVLSGVSTYI 152
Cdd:PRK01622 113 LEKQkeyQKEMMELYKSGNINPLAmGCLPLLIQMPILSAFYYAIrRTEEIASHSFLWF-NLGHAD--HILPIIAGLTYFI 189
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 497984170 153 MSKMLQpktNANSSSQAMPNMGMMNIVMAGMFTWMGFKMQSAIVIYWIINN 203
Cdd:PRK01622 190 QMKVSQ---SNGTSPEQVQMLKIQGIMMPAMILFMSFAAPSALVLYWITGG 237
|
|
| PRK02944 |
PRK02944 |
YidC family membrane integrase SpoIIIJ; |
30-203 |
2.04e-36 |
|
YidC family membrane integrase SpoIIIJ;
Pssm-ID: 179508 Cd Length: 255 Bit Score: 128.73 E-value: 2.04e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 30 SYGIAIIIFTIVVKVILLPLTIKQTRSSVKLAEVQPKTAAIQEKYKNDPQRAQQ----EILKLYKEENVSPMSGCLPLLI 105
Cdd:PRK02944 58 NYGLAIIVVTLLIRLLILPLMIKQTKSTKAMQALQPEMQKLKEKYSSKDQATQQklqqEMMQLFQKNGVNPLAGCLPIFI 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 106 QYPIIIVLFYA-FSTLNYHGAGFLWIpNLNQPDPYFILPVLSGVSTYIMSKMLQPKTnanssSQAMPNMGMMNIVMAGMF 184
Cdd:PRK02944 138 QMPILIAFYHAiMRTSEISKHSFLWF-DLGQADPYYILPIVAGITTFIQQKLMMAGT-----AGQNPQMAMMLWLMPIMI 211
|
170
....*....|....*....
gi 497984170 185 TWMGFKMQSAIVIYWIINN 203
Cdd:PRK02944 212 LIFAINFPAALSLYWVVGN 230
|
|
| PRK01315 |
PRK01315 |
putative inner membrane protein translocase component YidC; Provisional |
30-203 |
2.00e-28 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234941 Cd Length: 329 Bit Score: 109.83 E-value: 2.00e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 30 SYGIAIIIFTIVVKVILLPLTIKQTRSSVKLAEVQPKTAAIQEKYKNDPQRAQQEILKLYKEENVSPMSGCLPLLIQYPI 109
Cdd:PRK01315 41 TWVLSIVGLVIVIRALLIPLFVKQIKSQRNMQEIQPKMKKIQEKYKGDRERMSQEMMKLYKETGTNPLSSCLPLLLQMPI 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 110 IIVLfyaFSTLNYHGAGFLWIPNLNQP-----------------------DPYF--------ILPVLSGVSTYI-----M 153
Cdd:PRK01315 121 FFAL---YRVLDSAASRGDGIGPINPPllesfrhahifgaplaatflqalNAGNtavqvvaaVLIILMSASQFItqlqlM 197
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 497984170 154 SKMLQPKTNAnssSQAMPNMGMMNIVMAGMFTWMGFKMQSAIVIYWIINN 203
Cdd:PRK01315 198 TKNMPPEAKT---GPMAQQQKMLLYLFPLMFLVSGIAFPVGVLFYWLTSN 244
|
|
| PRK03449 |
PRK03449 |
putative inner membrane protein translocase component YidC; Provisional |
30-203 |
2.43e-25 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 179580 Cd Length: 304 Bit Score: 100.91 E-value: 2.43e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 30 SYGIAIIIFTIVVKVILLPLTIKQTRSSVKLAEVQPKTAAIQEKYKNDPQRAQQEILKLYKEENVSPMSGCLPLLIQYPI 109
Cdd:PRK03449 31 AWALSVMFLVFTLRALLYKPFVRQIRTTRKMQELQPQIKALQKKYGNDRQKMALEMQKLQKEHGFNPILGCLPMLAQIPV 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 110 IIVLFYAFSTLNYHGAGFLWIP-----NLNQPDPYF-------------------------------------------I 141
Cdd:PRK03449 111 FLGLFHVLRSFNRTGTGFGQLGmsveeNRNTPNYVFsaedvqsfldarlfgaplsayitmprsgldafvdftrtniilvG 190
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497984170 142 LP--VLSGVSTYIMSKML---QPKTNANSSSQAMPNMgMMNIVMAGMFTWMGFKMQSAIVIYWIINN 203
Cdd:PRK03449 191 VPlmIIAGVATHFNSRASvarQSAEAAANPQTAMMNK-LALWVFPLGVLVGGPFLPLAILLYWVSNN 256
|
|
| PRK02654 |
PRK02654 |
putative inner membrane protein translocase component YidC; Provisional |
30-120 |
5.85e-25 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 235058 Cd Length: 375 Bit Score: 101.21 E-value: 5.85e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 30 SYGIAIIIFTIVVKVILLPLTIKQTRSSVKLAEVQP----KTAAIQEKYKNDPQRAQQEILKLYKEENvSPMSGCLPLLI 105
Cdd:PRK02654 26 SYGLAIVALTLVIRFALYPLSAGSIRNMRRMKIAQPvmqkRQAEIQERYKNDPQKQQEEMGKLMKEFG-NPLAGCLPLLV 104
|
90
....*....|....*
gi 497984170 106 QYPIiivLFYAFSTL 120
Cdd:PRK02654 105 QMPI---LFALFATL 116
|
|
| PRK02463 |
PRK02463 |
OxaA-like protein precursor; Provisional |
20-201 |
2.57e-24 |
|
OxaA-like protein precursor; Provisional
Pssm-ID: 235040 Cd Length: 307 Bit Score: 98.26 E-value: 2.57e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 20 IQSVISNPNYSYGIAIIIFTIVVKVILLPLTIKQTRS----SVKLAEVQPKTAAIQEKYKN-----DPQRAQQEILKLYK 90
Cdd:PRK02463 49 IDYFANNLGLGFGLAIIIVTIIVRLIILPLGLYQSWKatyqSEKMAYLKPVFEPINERLKNattqeEKMAAQTELMAAQR 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 91 EENVSPMS--GCLPLLIQYPIIIVLFYAFS-TLNYHGAGFLWIPnLNQPDpyFILPVLSGVSTYIMSKMlqpktnansSS 167
Cdd:PRK02463 129 ENGISMLGgiGCLPLLIQMPFFSALYFAAQyTKGVSTSTFLGID-LGSPS--LVLTAIIGVLYFFQSWL---------SM 196
|
170 180 190
....*....|....*....|....*....|....*....
gi 497984170 168 QAMP-----NMGMMNIVMAGMFTWMGFKMQSAIVIYWII 201
Cdd:PRK02463 197 MGVPeeqreQMKAMMYMMPIMMVVFSFSSPAGVGLYWLV 235
|
|
| PRK02201 |
PRK02201 |
putative inner membrane protein translocase component YidC; Provisional |
16-202 |
9.99e-17 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 235012 Cd Length: 357 Bit Score: 78.13 E-value: 9.99e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 16 IHGMIQSVISNPNYSYGI--AIIIFTIVVKVILLPLTIKQTRSSVKLAEVQPKTAAIQEKYKNDP------QRAQQEILK 87
Cdd:PRK02201 116 ILSIMASQSLSELYGWSTilAIIVVVLIIRLISFLITFKSTFNQEKQEELQGKKAKIDAKYKDYKkdkqmkQRKQQEIQE 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 88 LYKEENVSPMSGCLPLLIQYPIIIVLF----------------YAFSTLNYH---GAGFLWIPNLnqpdpyfILPVLSGV 148
Cdd:PRK02201 196 LYKKHNISPFSPFVQMFVTLPIFIAVYrvvqslpsikvttwlgIDLSATSWQeifAGNWIYLPIL-------IIVVPVQA 268
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 497984170 149 STYIMSKMLQPKTNAN-----SSSQAMPNMGMMNIVMAGMFTWMGFKMQSAIVIYWIIN 202
Cdd:PRK02201 269 LSQLLPQILNKKKNKErtlnvKEKEALKKQNKTQNIISIVFIFFGVIFAAGVQIYWIIG 327
|
|
| PRK00247 |
PRK00247 |
putative inner membrane protein translocase component YidC; Validated |
27-116 |
2.17e-11 |
|
putative inner membrane protein translocase component YidC; Validated
Pssm-ID: 178945 [Multi-domain] Cd Length: 429 Bit Score: 62.95 E-value: 2.17e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497984170 27 PNYSYGIAIIIFTIVVKVILLPLTIKQTRSSVKLAEVQPKTAAIQEKYKNDPQRA-----QQEILKLYKEENVSPMSGCL 101
Cdd:PRK00247 28 DSLAWFASLFGLVITVRAIIAPFTWQQYKSGRTAAHIRPKRKALREEYKGKTDEAsirelQQKQKDLNKEYGYNPLAGCV 107
|
90
....*....|....*
gi 497984170 102 PLLIQYPIIIVLFYA 116
Cdd:PRK00247 108 PALIQIPVFLGLYQV 122
|
|
| |
