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Conserved domains on  [gi|497854916|ref|WP_010169072|]
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ABC transporter permease [Candidatus Epulonipiscium viviparus]

Protein Classification

ABC transporter permease( domain architecture ID 11427312)

ABC transporter permease similar to ABC oligopeptide transporter permease proteins (OppB, AppB, and AmiC), the transmembrane subunits (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Gene Ontology:  GO:0055085
PubMed:  18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-353 2.91e-90

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 273.10  E-value: 2.91e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916   1 MARYIATRIAWIFVMLFAILSMNFVLFKLAPAYPpttedeKTAYYNKQVSdgymevtlvsdQEEMEEIRYQMstattvrn 80
Cdd:COG0601    1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDP------AAALLGPRAT-----------PEAIAALRAEL-------- 55

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916  81 syyedkGdfirayLQVPISEQYFNWMGNViFRLDFGQSTRVevGRPVFDIIKDRMATTLTINIIALFFYTPIGLGLGIWA 160
Cdd:COG0601   56 ------G------LDQPLLVQYLDWLGGL-LRGDLGTSFVY--GRPVSDLIAERLPVTLELALLALLLALLIGIPLGILA 120

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 161 ALKKNKLTDNVISFMVMIMISIPSFVIMVMLVMIFGYGLDWVPTI-FPPKDADIMLRIRGYILPVLAMTFGPIAGLTRTT 239
Cdd:COG0601  121 ALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGWLPVSgRVSPWEDFLDALRHLILPALTLALGSLAGIARLT 200

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 240 RAELTEVLTSEYLLLARTKGLTRKQSVIRHALRNSLVPLVPGIIGSFAGLLSGSVIIEQIYSVPGTGTIFLRALTKNayD 319
Cdd:COG0601  201 RSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNR--D 278

                        330       340       350
                 ....*....|....*....|....*....|....
gi 497854916 320 YNLLLASTAFYTCIGLSAVLIVDLTYGLIDPRIR 353
Cdd:COG0601  279 YPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIR 312
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-353 2.91e-90

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 273.10  E-value: 2.91e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916   1 MARYIATRIAWIFVMLFAILSMNFVLFKLAPAYPpttedeKTAYYNKQVSdgymevtlvsdQEEMEEIRYQMstattvrn 80
Cdd:COG0601    1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDP------AAALLGPRAT-----------PEAIAALRAEL-------- 55

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916  81 syyedkGdfirayLQVPISEQYFNWMGNViFRLDFGQSTRVevGRPVFDIIKDRMATTLTINIIALFFYTPIGLGLGIWA 160
Cdd:COG0601   56 ------G------LDQPLLVQYLDWLGGL-LRGDLGTSFVY--GRPVSDLIAERLPVTLELALLALLLALLIGIPLGILA 120

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 161 ALKKNKLTDNVISFMVMIMISIPSFVIMVMLVMIFGYGLDWVPTI-FPPKDADIMLRIRGYILPVLAMTFGPIAGLTRTT 239
Cdd:COG0601  121 ALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGWLPVSgRVSPWEDFLDALRHLILPALTLALGSLAGIARLT 200

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 240 RAELTEVLTSEYLLLARTKGLTRKQSVIRHALRNSLVPLVPGIIGSFAGLLSGSVIIEQIYSVPGTGTIFLRALTKNayD 319
Cdd:COG0601  201 RSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNR--D 278

                        330       340       350
                 ....*....|....*....|....*....|....
gi 497854916 320 YNLLLASTAFYTCIGLSAVLIVDLTYGLIDPRIR 353
Cdd:COG0601  279 YPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIR 312
oppB PRK09471
oligopeptide ABC transporter permease OppB;
94-353 2.08e-37

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 136.35  E-value: 2.08e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916  94 LQVPISEQYFNWMGNVIfRLDFGQSTRVEvGRPVFDIIKDRMATTLTINIIALFFYTPIGLGLGIWAALKKNKLTDNVIS 173
Cdd:PRK09471  55 LNDPIMTQYFSYLKQLA-HGDFGPSFKYK-DYSVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVM 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 174 FMVMIMISIPSFVIMVMLVMIFGYGLDWVPTIFPPKDADIMLrirgyILPVLAMTFGPIAGLTRTTRAELTEVLTSEYLL 253
Cdd:PRK09471 133 GFAMTGVVIPSFVVAPLLVLIFAITLHWLPGGGWNGGALKFM-----ILPMVALSLAYIASIARITRGSMIEVLHSNFIR 207

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 254 LARTKGLTRKQSVIRHALRNSLVPLVPGIIGSFAGLLSGSVIIEQIYSVPGTGTIFLR-ALTKnayDYNLLLASTAFYTC 332
Cdd:PRK09471 208 TARAKGLPMRRIILRHALKPALLPVLSYMGPAFVGIITGSMVIETIFGLPGIGQLFVNgALNR---DYSLVLSLTILVGA 284

                        250       260
                 ....*....|....*....|.
gi 497854916 333 IGLSAVLIVDLTYGLIDPRIR 353
Cdd:PRK09471 285 LTILFNAIVDVLYAVIDPKIR 305
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 153-353 4.24e-26

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 102.76  E-value: 4.24e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916  153 GLGLGIWAALKKNKLTDNVISFMVMIMISIPSFVIMVMLVMIFgygldwvptifppkdadIMLRIRGYILPVLAMTFGPI 232
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIA-----------------ILSILGHGILPAIILALLGW 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916  233 AGLTRTTRAELTEVLTSEYLLLARTKGLTRKQSVIRHALRNSLVPLVPGIIGSFAGLLSGSVIIEQIYSVPGTGTIFLRA 312
Cdd:pfam00528  64 AGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEA 143

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 497854916  313 LtkNAYDYNLLLASTAFYTCIGLSAVLIVDLTYGLIDPRIR 353
Cdd:pfam00528 144 I--LGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 135-338 6.63e-17

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 77.70  E-value: 6.63e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 135 MATTLTINIIALFFYTPIGLGLGIWAALKKNKLtDNVISFMVMIMISIPSFVIMVMLVMIFGYGLDWvptifppkdadim 214
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKL-DRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGW------------- 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 215 LRIRGYILPVLAMTFGPIAGLTRTTRAELTEVLTSEYLLLARTKGLTRKQSVIRHALRNSLVPLVPGIIGSFAGLLSGSV 294
Cdd:cd06261   67 GILPGLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFA 146

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 497854916 295 IIEQIYSVPGTGTIFLRALTKNAYDYNLLLASTAFYTCIGLSAV 338
Cdd:cd06261  147 LVSFLGGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-353 2.91e-90

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 273.10  E-value: 2.91e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916   1 MARYIATRIAWIFVMLFAILSMNFVLFKLAPAYPpttedeKTAYYNKQVSdgymevtlvsdQEEMEEIRYQMstattvrn 80
Cdd:COG0601    1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDP------AAALLGPRAT-----------PEAIAALRAEL-------- 55

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916  81 syyedkGdfirayLQVPISEQYFNWMGNViFRLDFGQSTRVevGRPVFDIIKDRMATTLTINIIALFFYTPIGLGLGIWA 160
Cdd:COG0601   56 ------G------LDQPLLVQYLDWLGGL-LRGDLGTSFVY--GRPVSDLIAERLPVTLELALLALLLALLIGIPLGILA 120

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 161 ALKKNKLTDNVISFMVMIMISIPSFVIMVMLVMIFGYGLDWVPTI-FPPKDADIMLRIRGYILPVLAMTFGPIAGLTRTT 239
Cdd:COG0601  121 ALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGWLPVSgRVSPWEDFLDALRHLILPALTLALGSLAGIARLT 200

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 240 RAELTEVLTSEYLLLARTKGLTRKQSVIRHALRNSLVPLVPGIIGSFAGLLSGSVIIEQIYSVPGTGTIFLRALTKNayD 319
Cdd:COG0601  201 RSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNR--D 278

                        330       340       350
                 ....*....|....*....|....*....|....
gi 497854916 320 YNLLLASTAFYTCIGLSAVLIVDLTYGLIDPRIR 353
Cdd:COG0601  279 YPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIR 312
oppB PRK09471
oligopeptide ABC transporter permease OppB;
94-353 2.08e-37

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 136.35  E-value: 2.08e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916  94 LQVPISEQYFNWMGNVIfRLDFGQSTRVEvGRPVFDIIKDRMATTLTINIIALFFYTPIGLGLGIWAALKKNKLTDNVIS 173
Cdd:PRK09471  55 LNDPIMTQYFSYLKQLA-HGDFGPSFKYK-DYSVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVM 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 174 FMVMIMISIPSFVIMVMLVMIFGYGLDWVPTIFPPKDADIMLrirgyILPVLAMTFGPIAGLTRTTRAELTEVLTSEYLL 253
Cdd:PRK09471 133 GFAMTGVVIPSFVVAPLLVLIFAITLHWLPGGGWNGGALKFM-----ILPMVALSLAYIASIARITRGSMIEVLHSNFIR 207

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 254 LARTKGLTRKQSVIRHALRNSLVPLVPGIIGSFAGLLSGSVIIEQIYSVPGTGTIFLR-ALTKnayDYNLLLASTAFYTC 332
Cdd:PRK09471 208 TARAKGLPMRRIILRHALKPALLPVLSYMGPAFVGIITGSMVIETIFGLPGIGQLFVNgALNR---DYSLVLSLTILVGA 284

                        250       260
                 ....*....|....*....|.
gi 497854916 333 IGLSAVLIVDLTYGLIDPRIR 353
Cdd:PRK09471 285 LTILFNAIVDVLYAVIDPKIR 305
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 1-356 3.56e-37

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 135.98  E-value: 3.56e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916   1 MARYIATRIAWIFVMLFAILSMNFVLFKLAPAYPPTTedektayynkqvsdgYMEVTLVSDQEEMEEIRYQMSTattvrn 80
Cdd:PRK10352   1 MLRYILRRLLLLIPMLLAASVIIFLMLRLGTGDPALD---------------YLRLSNLPPTPEMLASTRTMLG------ 59

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916  81 syyedkgdfirayLQVPISEQYFNWMGNViFRLDFGQStrVEVGRPVFDIIKDRMATTLTINIIALFFYTPIGLGLGIWA 160
Cdd:PRK10352  60 -------------LDQPLYVQYGTWLWKA-LHLDFGIS--FATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWA 123

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 161 ALKKNKLTDNVISFMVMIMISIPSFVIMVMLVMIFGYGLDWVPTIfppkdadimlrirGY------ILPVLAMTFGPIAG 234
Cdd:PRK10352 124 ARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSVYLQWLPAM-------------GYggwqhiILPAVSIAFMSLAI 190

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 235 LTRTTRAELTEVLTSEYLLLARTKGLTRKQSVIRHALRNSLVPLVPGIIGSFAGLLSGSVIIEQIYSVPGTGTIFLRALT 314
Cdd:PRK10352 191 NARLLRASMLEVAGQRHVTWARLRGLSERQVERRHILRNASLPMITAVGMHIGELIGGTMIIENIFAWPGVGRYAVSAIF 270

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 497854916 315 KNayDYNLLLASTAFYTCIGLSAVLIVDLTYGLIDPRIRMGG 356
Cdd:PRK10352 271 NR--DYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRIRRHE 310
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 94-353 6.28e-35

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 129.83  E-value: 6.28e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916  94 LQVPISEQYFNWMGNVIfRLDFGQSTRVEvgRPVFDIIKDRMATTLTINIIALFFYTPIGLGLGIWAALKKNKLTDNVIS 173
Cdd:PRK15081  57 LDQPLPHQFWHYISNAL-QGDFGTSMVSR--RPVSEEIASRFMPTLWLTITSMVWAVIFGMAIGIASAVWRNRWPDRLGM 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 174 FMVMIMISIPSFVIMVMLVMIFGYGLDWVPTIfppkDADIMlriRGYILPVLAMTFGPIAGLTRTTRAELTEVLTSEYLL 253
Cdd:PRK15081 134 TLAVSGISFPAFALGMLLMQVFSVELGWLPTV----GADSW---QHYILPSLTLGAAVAAVMARFTRASFVEVLSEDYMR 206

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 254 LARTKGLTRKQSVIRHALRNSLVPLVPGIIGSFAGLLSGSVIIEQIYSVPGTGTIFLRALTKNayDYNLLLASTAFYTCI 333
Cdd:PRK15081 207 TARAKGVSETWVVLKHGLRNAMIPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMR--DYPVIQAEVLLFSLE 284

                        250       260
                 ....*....|....*....|
gi 497854916 334 GLSAVLIVDLTYGLIDPRIR 353
Cdd:PRK15081 285 FILINLVVDVLYAAINPAIR 304
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 1-356 6.59e-31

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 120.24  E-value: 6.59e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916   1 MARYIATRIAWIFVMLFAILSMNFVLFKLAPAYPPtteDEKTAyynkQVSDGYMEVTLVSDQEEMEEIRYQMSTATTVRN 80
Cdd:PRK15133   1 MGAYLIRRLLLVIPTLWAIITINFFIVQIAPGGPV---DQAIA----AIEFGQAGGLPGAGGEGVRASHAQTGVGNISDS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916  81 SYYEDKG-------DFIRAY-LQVPISEQYFNWMGNVIfRLDFGQStrVEVGRPVFDIIKDRMATTLTINIIALFFYTPI 152
Cdd:PRK15133  74 NYRGGRGldpeviaEITHRYgFDKPLHERYFKMLWDYI-RFDFGDS--LFRSASVLTLIKDSLPVSITLGLWSTLIIYLV 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 153 GLGLGIWAALKKNKLTDNVISFMVMIMISIPSFVIMVMLVMIFGYG--LDWVPT---IFPPKDA-DIMLRIRGYI----L 222
Cdd:PRK15133 151 SIPLGIRKAVRNGSRFDVWSSAFIIIGYAIPAFLFAILLIVFFAGGsyFDLFPLrglVSANFDSlPWYQKITDYLwhitL 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 223 PVLAMTFGPIAGLTRTTRAELTEVLTSEYLLLARTKGLTRKQSVIRHALRNSLVPLVPGIIGSFAGL-LSGSVIIEQIYS 301
Cdd:PRK15133 231 PVLATVIGGFAALTMLTKNSFLDEIRKQYVVTARAKGVSEKNILWKHVFRNAMLLVIAGFPATFISMfFTGSLLIEVMFS 310

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 497854916 302 VPGTGTIFLRALTKNayDYNLLLASTAFYTCIGLSAVLIVDLTYGLIDPRIRMGG 356
Cdd:PRK15133 311 LNGLGLLGYEATVSR--DYPVMFGTLYIFTLIGLLLNIVSDISYTLVDPRIDFEG 363
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
94-353 3.32e-29

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 115.29  E-value: 3.32e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916  94 LQVPISEQYFNWMGNViFRLDFGQSTRVEVgrPVFDIIKDRMATTLTINIIALFFYTPIGLGLGIWAALKKNKLTDNVIS 173
Cdd:PRK10914  58 LDKPMWQQYLHYIWGV-MHGDLGISLKSRI--PVWDEFVPRFKATLELGVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAV 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 174 FMVMIMISIPSFVIMVMLVMIFGYGLDWVP------------------------TIFPPKDADIMLRIRGYILPVLAMTF 229
Cdd:PRK10914 135 GLALTGYSMPIFWWGMMLIMLVSVHWNLTPvsgrvsdmvflddsnpltgfmlidTAIWGEDGNFIDAVAHMILPAIVLGT 214

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 230 GPIAGLTRTTRAELTEVLTSEYLLLARTKGLTRKQSVIRHALRNSLVPLVPGIIGSFAGLLSGSVIIEQIYSVPGTGTIF 309
Cdd:PRK10914 215 IPLAVIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWL 294

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 497854916 310 LRALTKNayDYNLLLASTAFYTCIGLSAVLIVDLTYGLIDPRIR 353
Cdd:PRK10914 295 IDALQRR--DYPVVQGGVLLVATMIILVNLLVDLLYGVVNPRIR 336
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 153-353 4.24e-26

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 102.76  E-value: 4.24e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916  153 GLGLGIWAALKKNKLTDNVISFMVMIMISIPSFVIMVMLVMIFgygldwvptifppkdadIMLRIRGYILPVLAMTFGPI 232
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIA-----------------ILSILGHGILPAIILALLGW 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916  233 AGLTRTTRAELTEVLTSEYLLLARTKGLTRKQSVIRHALRNSLVPLVPGIIGSFAGLLSGSVIIEQIYSVPGTGTIFLRA 312
Cdd:pfam00528  64 AGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEA 143

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 497854916  313 LtkNAYDYNLLLASTAFYTCIGLSAVLIVDLTYGLIDPRIR 353
Cdd:pfam00528 144 I--LGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
PRK15110 PRK15110
peptide ABC transporter permease SapB;
102-318 4.43e-19

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 86.67  E-value: 4.43e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 102 YFNWMGNvIFRLDFGQSTRVevGRPVFDIIKDRMATTLTINIIALFFYTPIGLGLGIWAALKKNKLTDNVISFMVMIMIS 181
Cdd:PRK15110  44 WVFWFNG-LLHWDFGVSSIN--GQPISEQLKEVFPATMELCILAFGFALLVGIPVGIIAGVTRHKWQDNLISALALLGFS 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 182 IPSFVIMVMLVMIFGYGLDWVP--------------TIF----------PPKDADIMLRIRGYILPVLAMTFGPIAGLTR 237
Cdd:PRK15110 121 IPVFWLALLLTLFFSLTLGWLPvsgrfdllyevkpvTGFalidawlsdsPWRDEMIMSAIRHMILPVITLAVAPTTEVIR 200

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 238 TTRAELTEVLTSEYLLLARTKGLTRKQSVIRHALRNSLVPLVPGIIGSFAGLLSGSVIIEQIYSVPGTGTIFLRALTKNA 317
Cdd:PRK15110 201 LMRISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQD 280


                 .
gi 497854916 318 Y 318
Cdd:PRK15110 281 Y 281
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 135-338 6.63e-17

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 77.70  E-value: 6.63e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 135 MATTLTINIIALFFYTPIGLGLGIWAALKKNKLtDNVISFMVMIMISIPSFVIMVMLVMIFGYGLDWvptifppkdadim 214
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKL-DRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGW------------- 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 215 LRIRGYILPVLAMTFGPIAGLTRTTRAELTEVLTSEYLLLARTKGLTRKQSVIRHALRNSLVPLVPGIIGSFAGLLSGSV 294
Cdd:cd06261   67 GILPGLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFA 146

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 497854916 295 IIEQIYSVPGTGTIFLRALTKNAYDYNLLLASTAFYTCIGLSAV 338
Cdd:cd06261  147 LVSFLGGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 137-289 3.26e-12

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 65.90  E-value: 3.26e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 137 TTLTINIIALFFYTPIGLGLGIWAALKKnKLTDNVISFMVMIMISIPSFVIMVMLVMIFGYGLDWVptifppkdadimlr 216
Cdd:COG1173   80 ISLLVGLLAVLIALVIGVLLGLLAGYFG-GWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNV-------------- 144

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 217 irgyilpVLAMTFGPIAGLTRTTRAELTEVLTSEYLLLARTKGLTRKQSVIRHALRNSLVPL-------VPGIIGSFAGL 289
Cdd:COG1173  145 -------ILALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLivqatlgIASAILAEAGL 217
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
122-279 1.16e-04

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 43.27  E-value: 1.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497854916 122 EVGRPVFDIIKDRMATTLTINIIALFFYTPIGLGLGIWAALKKNKLtDNVISFMVMIMISIPSFVIMVMLVMIFGygldw 201
Cdd:PRK09881  80 EVGRDLFSRVLVGSQQSILAGLVVVAIAGMIGSLLGCLSGVLGGRA-DAIIMRIMDIMLSIPSLVLTMALAAALG----- 153

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 497854916 202 vPTIFPPKDADIMLRIRGYIlpvlamtfgpiagltRTTRAELTEVLTSEYLLLARTKGLTRKQSVIRHALRNSLVPLV 279
Cdd:PRK09881 154 -PSLFNAMLAIAIVRIPFYV---------------RLARGQALVVRQYTYVQAAKTFGASRWHLISWHILRNSLPPLI 215
PRK10952 PRK10952
proline/glycine betaine ABC transporter permease ProW;
138-198 2.12e-04

proline/glycine betaine ABC transporter permease ProW;


Pssm-ID: 236805  Cd Length: 355  Bit Score: 42.77  E-value: 2.12e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497854916 138 TLTINIIALFFYTPIGLGLGIWaaLKKNKLTDNVISFMVMIMISIPSFVIMVMLVMIFGYG 198
Cdd:PRK10952 149 TLALVLTALLFCIVIGLPLGIW--LARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIG 207
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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