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Conserved domains on  [gi|497571723|ref|WP_009885907|]
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FAD-dependent oxidoreductase [Mycoplasmoides genitalium]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 1562436)

NAD(P)/FAD-dependent oxidoreductase catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Pyr_redox_2 super family cl39093
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 2-458 1.55e-89

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


The actual alignment was detected with superfamily member PRK09564:

Pssm-ID: 476868 [Multi-domain]  Cd Length: 444  Bit Score: 280.00  E-value: 1.55e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723   2 KKVIVIGINHAGTSFIRTLLSKSKDFKVNAYDRNTNISFLGCGIALAVSGVVKNTDDLFYSNPEELKQMGANIFMSHDVT 81
Cdd:PRK09564   1 MKIIIIGGTAAGMSAAAKAKRLNKELEITVYEKTDIVSFGACGLPYFVGGFFDDPNTMIARTPEEFIKSGIDVKTEHEVV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  82 NIDLIKKQVTVRDLTSNKEFTDQFDQLVIASGAWPICMNVENkvthkplefnytdkycGNVKNLISCKLYQHALTLIDSF 161
Cdd:PRK09564  81 KVDAKNKTITVKNLKTGSIFNDTYDKLMIATGARPIIPPIKN----------------INLENVYTLKSMEDGLALKELL 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 162 rKDKTIKSVAIVGSGYIGLELAEAAWLCKKQVTVIDLLDKPAGNNFDHEFTDELEKVMQKDGLKLMMGCSVKGFVvdsTN 241
Cdd:PRK09564 145 -KDEEIKNIVIIGAGFIGLEAVEAAKHLGKNVRIIQLEDRILPDSFDKEITDVMEEELRENGVELHLNEFVKSLI---GE 220

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 242 NVVKGVETDKGIVNADLVIQSIGFRPSTKFVpKDQNFEFIHNGSIKVNEFlQALNHKDVYVIGGCAAIYNAASEQYENID 321
Cdd:PRK09564 221 DKVEGVVTDKGEYEADVVIVATGVKPNTEFL-EDTGLKTLKNGAIIVDEY-GETSIENIYAAGDCATIYNIVSNKNVYVP 298

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 322 LATNAVKSGLVAAMHIIGsNQVKLQSIVGTNALHIFGLNLAACGLTEQRAKKLGFDVGISVVDDNDRPEFMGSYDKVRFK 401
Cdd:PRK09564 299 LATTANKLGRMVGENLAG-RHVSFKGTLGSACIKVLDLEAARTGLTEEEAKKLGIDYKTVFIKDKNHTNYYPGQEDLYVK 377

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 497571723 402 LVYDKKTLRILGAQLLSWNtNHSEIIFYIALAIQKQMLLTELGLVDVYFLPhynkPF 458
Cdd:PRK09564 378 LIYEADTKVILGGQIIGKK-GAVLRIDALAVAIYAKLTTQELGMMDFCYAP----PF 429
 
Name Accession Description Interval E-value
PRK09564 PRK09564
coenzyme A disulfide reductase; Reviewed
 2-458 1.55e-89

coenzyme A disulfide reductase; Reviewed


Pssm-ID: 181958 [Multi-domain]  Cd Length: 444  Bit Score: 280.00  E-value: 1.55e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723   2 KKVIVIGINHAGTSFIRTLLSKSKDFKVNAYDRNTNISFLGCGIALAVSGVVKNTDDLFYSNPEELKQMGANIFMSHDVT 81
Cdd:PRK09564   1 MKIIIIGGTAAGMSAAAKAKRLNKELEITVYEKTDIVSFGACGLPYFVGGFFDDPNTMIARTPEEFIKSGIDVKTEHEVV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  82 NIDLIKKQVTVRDLTSNKEFTDQFDQLVIASGAWPICMNVENkvthkplefnytdkycGNVKNLISCKLYQHALTLIDSF 161
Cdd:PRK09564  81 KVDAKNKTITVKNLKTGSIFNDTYDKLMIATGARPIIPPIKN----------------INLENVYTLKSMEDGLALKELL 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 162 rKDKTIKSVAIVGSGYIGLELAEAAWLCKKQVTVIDLLDKPAGNNFDHEFTDELEKVMQKDGLKLMMGCSVKGFVvdsTN 241
Cdd:PRK09564 145 -KDEEIKNIVIIGAGFIGLEAVEAAKHLGKNVRIIQLEDRILPDSFDKEITDVMEEELRENGVELHLNEFVKSLI---GE 220

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 242 NVVKGVETDKGIVNADLVIQSIGFRPSTKFVpKDQNFEFIHNGSIKVNEFlQALNHKDVYVIGGCAAIYNAASEQYENID 321
Cdd:PRK09564 221 DKVEGVVTDKGEYEADVVIVATGVKPNTEFL-EDTGLKTLKNGAIIVDEY-GETSIENIYAAGDCATIYNIVSNKNVYVP 298

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 322 LATNAVKSGLVAAMHIIGsNQVKLQSIVGTNALHIFGLNLAACGLTEQRAKKLGFDVGISVVDDNDRPEFMGSYDKVRFK 401
Cdd:PRK09564 299 LATTANKLGRMVGENLAG-RHVSFKGTLGSACIKVLDLEAARTGLTEEEAKKLGIDYKTVFIKDKNHTNYYPGQEDLYVK 377

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 497571723 402 LVYDKKTLRILGAQLLSWNtNHSEIIFYIALAIQKQMLLTELGLVDVYFLPhynkPF 458
Cdd:PRK09564 378 LIYEADTKVILGGQIIGKK-GAVLRIDALAVAIYAKLTTQELGMMDFCYAP----PF 429
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 32-365 4.95e-71

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 228.16  E-value: 4.95e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  32 YDRNTNISFLGCGIALAVSGVVKNTDDLFYSNPEELKQMGANIFMSHDVTNIDLIKKQVTVRDLTsnkefTDQFDQLVIA 111
Cdd:COG0446   11 IEKGPHHSYQPCGLPYYVGGGIKDPEDLLVRTPESFERKGIDVRTGTEVTAIDPEAKTVTLRDGE-----TLSYDKLVLA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 112 SGAWPICMNVENKvthkplefnytdkycgNVKNLISCKLYQHALTLIDSFrKDKTIKSVAIVGSGYIGLELAEAAWLCKK 191
Cdd:COG0446   86 TGARPRPPPIPGL----------------DLPGVFTLRTLDDADALREAL-KEFKGKRAVVIGGGPIGLELAEALRKRGL 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 192 QVTVIDLLDKPAGnNFDHEFTDELEKVMQKDGLKLMMGCSVKGFVVDstnNVVKGVETDKGIVNADLVIQSIGFRPSTKF 271
Cdd:COG0446  149 KVTLVERAPRLLG-VLDPEMAALLEEELREHGVELRLGETVVAIDGD---DKVAVTLTDGEEIPADLVVVAPGVRPNTEL 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 272 VpKDQNFEFIHNGSIKVNEFLQAlNHKDVYVIGGCAAIYNAASEQYENIDLATNAVKSGLVAAMHIIGSNQVKLQsiVGT 351
Cdd:COG0446  225 A-KDAGLALGERGWIKVDETLQT-SDPDVYAAGDCAEVPHPVTGKTVYIPLASAANKQGRVAAENILGGPAPFPG--LGT 300

                        330
                 ....*....|....
gi 497571723 352 NALHIFGLNLAACG 365
Cdd:COG0446  301 FISKVFDLCIASTG 314
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 2-330 4.84e-62

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 204.09  E-value: 4.84e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723    2 KKVIVIGINHAGTSFIRTLlsKSKDFKVNAYDRNTNISFLGCGIALAVSGVVKNTDDLFY------SNPEELKQMGANIF 75
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTL--AQLGGKVTLIEDEGTCPYGGCVLSKALLGAAEAPEIASLwadlykRKEEVVKKLNNGIE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723   76 MSHD--VTNIDLIKKQVTVRDLTSNKEFTDQFDQLVIASGAWPICMNVENkvthkplefnYTDKYCGNVKNLISCKLYQH 153
Cdd:pfam07992  79 VLLGteVVSIDPGAKKVVLEELVDGDGETITYDRLVIATGARPRLPPIPG----------VELNVGFLVRTLDSAEALRL 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  154 ALTLidsfrkdktiKSVAIVGSGYIGLELAEAAWLCKKQVTVIDLLDKPAgNNFDHEFTDELEKVMQKDGLKLMMGCSVK 233
Cdd:pfam07992 149 KLLP----------KRVVVVGGGYIGVELAAALAKLGKEVTLIEALDRLL-RAFDEEISAALEKALEKNGVEVRLGTSVK 217

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  234 GFVVDstNNVVKGVETDKGIVNADLVIQSIGFRPSTKFVpKDQNFEFIHNGSIKVNEFLQAlNHKDVYVIGGCaaiynaa 313
Cdd:pfam07992 218 EIIGD--GDGVEVILKDGTEIDADLVVVAIGRRPNTELL-EAAGLELDERGGIVVDEYLRT-SVPGIYAAGDC------- 286

                         330
                  ....*....|....*..
gi 497571723  314 seQYENIDLATNAVKSG 330
Cdd:pfam07992 287 --RVGGPELAQNAVAQG 301
nitri_red_nirB TIGR02374
nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen ...
 4-365 1.13e-09

nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen metabolism]


Pssm-ID: 162827 [Multi-domain]  Cd Length: 785  Bit Score: 60.61  E-value: 1.13e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723    4 VIVIGINHAGTSFIRTLLSKSKD-FKVNAYDRNTNISFLGCGIALAVSGVvKNTDDLFYSNPEELKQMGANIFMSHDVTN 82
Cdd:TIGR02374   1 LVLVGNGMAGHRCIEEVLKLNRHmFEITIFGEEPHPNYNRILLSSVLQGE-ADLDDITLNSKDWYEKHGITLYTGETVIQ 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723   83 IDLIKKQVtvrdLTSNKEfTDQFDQLVIASGAWPICMNVenKVTHKPLEFNYTDkyCGNVKNLISCKlyqhaltlidsfr 162
Cdd:TIGR02374  80 IDTDQKQV----ITDAGR-TLSYDKLILATGSYPFILPI--PGADKKGVYVFRT--IEDLDAIMAMA------------- 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  163 kdKTIKSVAIVGSGYIGLELAEAAWLCKKQVTVIDLLDKPAGNNFDHEFTDELEKVMQKDGLKLMMGcsvKGFVVDSTNN 242
Cdd:TIGR02374 138 --QRFKKAAVIGGGLLGLEAAVGLQNLGMDVSVIHHAPGLMAKQLDQTAGRLLQRELEQKGLTFLLE---KDTVEIVGAT 212

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  243 VVKGVE-TDKGIVNADLVIQSIGFRPSTKFVPKDQnfeFIHNGSIKVNEFLQAlNHKDVYVIGGCAAIYNAAseqyenID 321
Cdd:TIGR02374 213 KADRIRfKDGSSLEADLIVMAAGIRPNDELAVSAG---IKVNRGIIVNDSMQT-SDPDIYAVGECAEHNGRV------YG 282

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 497571723  322 LATNAVKSGLVAAMHIIGSNQVKLQSIVGTNALHIFGLNLAACG 365
Cdd:TIGR02374 283 LVAPLYEQAKVLADHICGVECEEYEGSDLSAKLKLLGVDVWSAG 326
 
Name Accession Description Interval E-value
PRK09564 PRK09564
coenzyme A disulfide reductase; Reviewed
 2-458 1.55e-89

coenzyme A disulfide reductase; Reviewed


Pssm-ID: 181958 [Multi-domain]  Cd Length: 444  Bit Score: 280.00  E-value: 1.55e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723   2 KKVIVIGINHAGTSFIRTLLSKSKDFKVNAYDRNTNISFLGCGIALAVSGVVKNTDDLFYSNPEELKQMGANIFMSHDVT 81
Cdd:PRK09564   1 MKIIIIGGTAAGMSAAAKAKRLNKELEITVYEKTDIVSFGACGLPYFVGGFFDDPNTMIARTPEEFIKSGIDVKTEHEVV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  82 NIDLIKKQVTVRDLTSNKEFTDQFDQLVIASGAWPICMNVENkvthkplefnytdkycGNVKNLISCKLYQHALTLIDSF 161
Cdd:PRK09564  81 KVDAKNKTITVKNLKTGSIFNDTYDKLMIATGARPIIPPIKN----------------INLENVYTLKSMEDGLALKELL 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 162 rKDKTIKSVAIVGSGYIGLELAEAAWLCKKQVTVIDLLDKPAGNNFDHEFTDELEKVMQKDGLKLMMGCSVKGFVvdsTN 241
Cdd:PRK09564 145 -KDEEIKNIVIIGAGFIGLEAVEAAKHLGKNVRIIQLEDRILPDSFDKEITDVMEEELRENGVELHLNEFVKSLI---GE 220

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 242 NVVKGVETDKGIVNADLVIQSIGFRPSTKFVpKDQNFEFIHNGSIKVNEFlQALNHKDVYVIGGCAAIYNAASEQYENID 321
Cdd:PRK09564 221 DKVEGVVTDKGEYEADVVIVATGVKPNTEFL-EDTGLKTLKNGAIIVDEY-GETSIENIYAAGDCATIYNIVSNKNVYVP 298

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 322 LATNAVKSGLVAAMHIIGsNQVKLQSIVGTNALHIFGLNLAACGLTEQRAKKLGFDVGISVVDDNDRPEFMGSYDKVRFK 401
Cdd:PRK09564 299 LATTANKLGRMVGENLAG-RHVSFKGTLGSACIKVLDLEAARTGLTEEEAKKLGIDYKTVFIKDKNHTNYYPGQEDLYVK 377

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 497571723 402 LVYDKKTLRILGAQLLSWNtNHSEIIFYIALAIQKQMLLTELGLVDVYFLPhynkPF 458
Cdd:PRK09564 378 LIYEADTKVILGGQIIGKK-GAVLRIDALAVAIYAKLTTQELGMMDFCYAP----PF 429
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 32-365 4.95e-71

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 228.16  E-value: 4.95e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  32 YDRNTNISFLGCGIALAVSGVVKNTDDLFYSNPEELKQMGANIFMSHDVTNIDLIKKQVTVRDLTsnkefTDQFDQLVIA 111
Cdd:COG0446   11 IEKGPHHSYQPCGLPYYVGGGIKDPEDLLVRTPESFERKGIDVRTGTEVTAIDPEAKTVTLRDGE-----TLSYDKLVLA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 112 SGAWPICMNVENKvthkplefnytdkycgNVKNLISCKLYQHALTLIDSFrKDKTIKSVAIVGSGYIGLELAEAAWLCKK 191
Cdd:COG0446   86 TGARPRPPPIPGL----------------DLPGVFTLRTLDDADALREAL-KEFKGKRAVVIGGGPIGLELAEALRKRGL 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 192 QVTVIDLLDKPAGnNFDHEFTDELEKVMQKDGLKLMMGCSVKGFVVDstnNVVKGVETDKGIVNADLVIQSIGFRPSTKF 271
Cdd:COG0446  149 KVTLVERAPRLLG-VLDPEMAALLEEELREHGVELRLGETVVAIDGD---DKVAVTLTDGEEIPADLVVVAPGVRPNTEL 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 272 VpKDQNFEFIHNGSIKVNEFLQAlNHKDVYVIGGCAAIYNAASEQYENIDLATNAVKSGLVAAMHIIGSNQVKLQsiVGT 351
Cdd:COG0446  225 A-KDAGLALGERGWIKVDETLQT-SDPDVYAAGDCAEVPHPVTGKTVYIPLASAANKQGRVAAENILGGPAPFPG--LGT 300

                        330
                 ....*....|....
gi 497571723 352 NALHIFGLNLAACG 365
Cdd:COG0446  301 FISKVFDLCIASTG 314
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 2-330 4.84e-62

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 204.09  E-value: 4.84e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723    2 KKVIVIGINHAGTSFIRTLlsKSKDFKVNAYDRNTNISFLGCGIALAVSGVVKNTDDLFY------SNPEELKQMGANIF 75
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTL--AQLGGKVTLIEDEGTCPYGGCVLSKALLGAAEAPEIASLwadlykRKEEVVKKLNNGIE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723   76 MSHD--VTNIDLIKKQVTVRDLTSNKEFTDQFDQLVIASGAWPICMNVENkvthkplefnYTDKYCGNVKNLISCKLYQH 153
Cdd:pfam07992  79 VLLGteVVSIDPGAKKVVLEELVDGDGETITYDRLVIATGARPRLPPIPG----------VELNVGFLVRTLDSAEALRL 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  154 ALTLidsfrkdktiKSVAIVGSGYIGLELAEAAWLCKKQVTVIDLLDKPAgNNFDHEFTDELEKVMQKDGLKLMMGCSVK 233
Cdd:pfam07992 149 KLLP----------KRVVVVGGGYIGVELAAALAKLGKEVTLIEALDRLL-RAFDEEISAALEKALEKNGVEVRLGTSVK 217

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  234 GFVVDstNNVVKGVETDKGIVNADLVIQSIGFRPSTKFVpKDQNFEFIHNGSIKVNEFLQAlNHKDVYVIGGCaaiynaa 313
Cdd:pfam07992 218 EIIGD--GDGVEVILKDGTEIDADLVVVAIGRRPNTELL-EAAGLELDERGGIVVDEYLRT-SVPGIYAAGDC------- 286

                         330
                  ....*....|....*..
gi 497571723  314 seQYENIDLATNAVKSG 330
Cdd:pfam07992 287 --RVGGPELAQNAVAQG 301
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
1-417 2.65e-40

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 149.14  E-value: 2.65e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723   1 MKKVIVIGINHAGTSFIRTLLSKSKDFKV--------NAYDRntnisflgcgIAL--AVSGVVKnTDDLFYSNPEELKQM 70
Cdd:COG1251    1 KMRIVIIGAGMAGVRAAEELRKLDPDGEItvigaephPPYNR----------PPLskVLAGETD-EEDLLLRPADFYEEN 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  71 GANIFMSHDVTNIDLIKKQVTvrdLTSNKEFTdqFDQLVIASGAWPICMNVENkvTHKPLEFNYTDkycgnvknlisckl 150
Cdd:COG1251   70 GIDLRLGTRVTAIDRAARTVT---LADGETLP--YDKLVLATGSRPRVPPIPG--ADLPGVFTLRT-------------- 128

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 151 YQHALTLIDSFRKDktiKSVAIVGSGYIGLELAEAAWLCKKQVTVIDLLDKPAGNNFDHEFTDELEKVMQKDGLKLMMGC 230
Cdd:COG1251  129 LDDADALRAALAPG---KRVVVIGGGLIGLEAAAALRKRGLEVTVVERAPRLLPRQLDEEAGALLQRLLEALGVEVRLGT 205

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 231 SVKGFVVDSTnnvVKGVETDKG-IVNADLVIQSIGFRPSTKFVpKDQNFEfIHNGsIKVNEFLQAlNHKDVYVIGGCAAI 309
Cdd:COG1251  206 GVTEIEGDDR---VTGVRLADGeELPADLVVVAIGVRPNTELA-RAAGLA-VDRG-IVVDDYLRT-SDPDIYAAGDCAEH 278

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 310 YNAASEQYeNIDLATNAVKSGLVAAMHIIGSNqVKLQSIVGTNALHIFGLNLAACGLTEQrakklgfdvGISVVDDNDRP 389
Cdd:COG1251  279 PGPVYGRR-VLELVAPAYEQARVAAANLAGGP-AAYEGSVPSTKLKVFGVDVASAGDAEG---------DEEVVVRGDPA 347

                        410       420
                 ....*....|....*....|....*...
gi 497571723 390 EfmGSYDKVRFKlvyDKktlRILGAQLL 417
Cdd:COG1251  348 R--GVYKKLVLR---DG---RLVGAVLV 367
PRK13512 PRK13512
coenzyme A disulfide reductase; Provisional
 1-457 3.03e-33

coenzyme A disulfide reductase; Provisional


Pssm-ID: 184103 [Multi-domain]  Cd Length: 438  Bit Score: 130.67  E-value: 3.03e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723   1 MKKVIVIGINHAGTSFIRTLLSKSKDFKVNAYDRNTNISFLGCGIALAVSGVVKNTDDLFYSNPE---ELKQMGANIFms 77
Cdd:PRK13512   1 MPKIIVVGAVAGGATCASQIRRLDKESDIIIFEKDRDMSFANCALPYYIGEVVEDRKYALAYTPEkfyDRKQITVKTY-- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  78 HDVTNIDLIKKQVTVRDLTSNKEFTDQFDQLVIASGAWPICMNVENKVTHKPLEFNYTDKycgnvknliscklyqhaltl 157
Cdd:PRK13512  79 HEVIAINDERQTVTVLNRKTNEQFEESYDKLILSPGASANSLGFESDITFTLRNLEDTDA-------------------- 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 158 IDSFRKDKTIKSVAIVGSGYIGLELAEAAWLCKKQVTVIDLLDKpAGNNFDHEFTDELEKVMQKDGLKLMMG---CSVKG 234
Cdd:PRK13512 139 IDQFIKANQVDKALVVGAGYISLEVLENLYERGLHPTLIHRSDK-INKLMDADMNQPILDELDKREIPYRLNeeiDAING 217

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 235 FVVDSTNNVVKgvetdkgivNADLVIQSIGFRPSTKFVpKDQNFEFIHNGSIKVNEFLQAlNHKDVYVIGgcaaiyNAAS 314
Cdd:PRK13512 218 NEVTFKSGKVE---------HYDMIIEGVGTHPNSKFI-ESSNIKLDDKGFIPVNDKFET-NVPNIYAIG------DIIT 280

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 315 EQYENID------LATNAVKSGLVAAMHIIGSNQVKLQSIVGTNALHIFGLNLAACGLTEQRAKKlgFDVGISVVDDNDR 388
Cdd:PRK13512 281 SHYRHVDlpasvpLAWGAHRAASIVAEQIAGNDTIEFKGFLGNNIVKFFDYTFASVGVKPNELKQ--FDYKMVEVTQGAH 358

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497571723 389 PEFMGSYDKVRFKLVYDKKTLRILGAQLLSwNTNHSEIIFYIALAIQKQMLLTELGLVDVYFLPHYNKP 457
Cdd:PRK13512 359 ANYYPGNSPLHLRVYYDTSNRKILRAAAVG-KEGADKRIDVLSMAMMNQLTVDELTEFEVAYAPPYSHP 426
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 168-443 1.25e-31

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 126.35  E-value: 1.25e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 168 KSVAIVGSGYIGLELAEA-----AwlckkQVTVIDLLDKPAGnNFDHEFTDELEKVMQKDGLKLMMGCSVKGFVVDSTNN 242
Cdd:COG1249  169 KSLVVIGGGYIGLEFAQIfarlgS-----EVTLVERGDRLLP-GEDPEISEALEKALEKEGIDILTGAKVTSVEKTGDGV 242

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 243 VVKgVETDKGI--VNADLVIQSIGFRPSTkfvpKDQNFE-----FIHNGSIKVNEFLQAlNHKDVYVIGGCAAIYNaase 315
Cdd:COG1249  243 TVT-LEDGGGEeaVEADKVLVATGRRPNT----DGLGLEaagveLDERGGIKVDEYLRT-SVPGIYAIGDVTGGPQ---- 312

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 316 qyenidLATNAVKSGLVAAMHIIGSNQVKLQ-----SIVGTNalhifgLNLAACGLTEQRAKKLGFDVGISVVD--DNDR 388
Cdd:COG1249  313 ------LAHVASAEGRVAAENILGKKPRPVDyraipSVVFTD------PEIASVGLTEEEAREAGIDVKVGKFPfaANGR 380

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 497571723 389 PEFMGSYDkVRFKLVYDKKTLRILGAQLLSwnTNHSEIIFYIALAIQKQMLLTEL 443
Cdd:COG1249  381 ALALGETE-GFVKLIADAETGRILGAHIVG--PHAGELIHEAALAMEMGLTVEDL 432
PRK06416 PRK06416
dihydrolipoamide dehydrogenase; Reviewed
 89-445 8.45e-22

dihydrolipoamide dehydrogenase; Reviewed


Pssm-ID: 235798 [Multi-domain]  Cd Length: 462  Bit Score: 97.52  E-value: 8.45e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  89 QVTVRDLTSNKEFTdqFDQLVIASGAWPIC---MNVENKVThkpleFNYTdkycgnvknliscklyqHALTLidsfrkDK 165
Cdd:PRK06416 121 TVRVMTEDGEQTYT--AKNIILATGSRPRElpgIEIDGRVI-----WTSD-----------------EALNL------DE 170

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 166 TIKSVAIVGSGYIGLELAE--AAWLCKkqVTVIDLLDK--PagnNFDHEFTDELEKVMQKDGLKLMMGCSVKGfvVDSTN 241
Cdd:PRK06416 171 VPKSLVVIGGGYIGVEFASayASLGAE--VTIVEALPRilP---GEDKEISKLAERALKKRGIKIKTGAKAKK--VEQTD 243

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 242 NVVKgVETDKG----IVNADLVIQSIGFRPSTKfvpkDQNFEF----IHNGSIKVNEFLQAlNHKDVYVIG---GCAAIY 310
Cdd:PRK06416 244 DGVT-VTLEDGgkeeTLEADYVLVAVGRRPNTE----NLGLEElgvkTDRGFIEVDEQLRT-NVPNIYAIGdivGGPMLA 317

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 311 NAASEQyenidlatnavksGLVAAMHIIGSNQ-VKLQSIVGTNALHIfglNLAACGLTEQRAKKLGFDVGISVVD--DND 387
Cdd:PRK06416 318 HKASAE-------------GIIAAEAIAGNPHpIDYRGIPAVTYTHP---EVASVGLTEAKAKEEGFDVKVVKFPfaGNG 381

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 497571723 388 RPEFMGSYDKVrFKLVYDKKTLRILGAQLLSwnTNHSEIIFYIALAIQKQMLLTELGL 445
Cdd:PRK06416 382 KALALGETDGF-VKLIFDKKDGEVLGAHMVG--ARASELIQEAQLAINWEATPEDLAL 436
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 155-454 3.01e-20

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 92.93  E-value: 3.01e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 155 LTLIDSFRKDKTIKSVAIVGSGYIGLELAEA-AWLCKKqVTVIDLLDKpAGNNFDHEFTDELEKVMQKDgLKLMMGCSVK 233
Cdd:PRK06292 157 LTSDDAFELDKLPKSLAVIGGGVIGLELGQAlSRLGVK-VTVFERGDR-ILPLEDPEVSKQAQKILSKE-FKIKLGAKVT 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 234 GFVVDSTNNVVKGVETDKGI-VNADLVIQSIGFRPSTKF-------VPKDQnfefihNGSIKVNEFLQAlNHKDVYVIGG 305
Cdd:PRK06292 234 SVEKSGDEKVEELEKGGKTEtIEADYVLVATGRRPNTDGlglentgIELDE------RGRPVVDEHTQT-SVPGIYAAGD 306

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 306 CAAIYnaaseqyeniDLATNAVKSGLVAAMHIIGSNQVKLQ-----SIVGTNAlhifglNLAACGLTEQRAKKLGFDVGI 380
Cdd:PRK06292 307 VNGKP----------PLLHEAADEGRIAAENAAGDVAGGVRyhpipSVVFTDP------QIASVGLTEEELKAAGIDYVV 370

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 497571723 381 SVVD--DNDRPEFMGSyDKVRFKLVYDKKTLRILGAQLLSwnTNHSEIIFYIALAIQKQmlLTELGLVDvyfLPHY 454
Cdd:PRK06292 371 GEVPfeAQGRARVMGK-NDGFVKVYADKKTGRLLGAHIIG--PDAEHLIHLLAWAMQQG--LTVEDLLR---MPFY 438
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
1-309 1.58e-19

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 90.19  E-value: 1.58e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723   1 MKKVIVIGINHAGTSFIRTLLSK-SKDFKVNAYDRNTNISFLGCGIALAVSGVvkNTDDLFYSNPEELKQMGANIFMSHd 79
Cdd:COG1252    1 MKRIVIVGGGFAGLEAARRLRKKlGGDAEVTLIDPNPYHLFQPLLPEVAAGTL--SPDDIAIPLRELLRRAGVRFIQGE- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  80 VTNIDLIKKQVTvrdLTSNKEFTdqFDQLVIASGAwpicmnvenkvthkplEFNYtDKYCGNVKNLISCKLYQHALT--- 156
Cdd:COG1252   78 VTGIDPEARTVT---LADGRTLS--YDYLVIATGS----------------VTNF-FGIPGLAEHALPLKTLEDALAlre 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 157 -LIDSFRKDKTIK--SVAIVGSGYIGLELA-EAAWLCKK------------QVTVIDLLDKPaGNNFDHEFTDELEKVMQ 220
Cdd:COG1252  136 rLLAAFERAERRRllTIVVVGGGPTGVELAgELAELLRKllrypgidpdkvRITLVEAGPRI-LPGLGEKLSEAAEKELE 214

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 221 KDGLKLMMGCSVKGFVVDstnnvvkGVETDKG-IVNADLVIQSIGFRPSTkfVPKDQNFEFIHNGSIKVNEFLQALNHKD 299
Cdd:COG1252  215 KRGVEVHTGTRVTEVDAD-------GVTLEDGeEIPADTVIWAAGVKAPP--LLADLGLPTDRRGRVLVDPTLQVPGHPN 285

                        330
                 ....*....|
gi 497571723 300 VYVIGGCAAI 309
Cdd:COG1252  286 VFAIGDCAAV 295
PRK06370 PRK06370
FAD-containing oxidoreductase;
168-444 1.84e-16

FAD-containing oxidoreductase;


Pssm-ID: 235787 [Multi-domain]  Cd Length: 463  Bit Score: 81.40  E-value: 1.84e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 168 KSVAIVGSGYIGLELAEAAWLCKKQVTVID----LLdkpagNNFDHEFTDELEKVMQKDGLKLMMGCSVKGFVVDSTNNV 243
Cdd:PRK06370 172 EHLVIIGGGYIGLEFAQMFRRFGSEVTVIErgprLL-----PREDEDVAAAVREILEREGIDVRLNAECIRVERDGDGIA 246

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 244 VK-GVETDKGIVNADLVIQSIGFRPSTkfvpKDQNFE-----FIHNGSIKVNEFLQAlNHKDVYVIGGC---AAIYNAAS 314
Cdd:PRK06370 247 VGlDCNGGAPEITGSHILVAVGRVPNT----DDLGLEaagveTDARGYIKVDDQLRT-TNPGIYAAGDCngrGAFTHTAY 321

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 315 EQYEnidlatnavksglVAAMHIIGSNQVKLQSIVGTNALHIfGLNLAACGLTEQRAKKLGF----------DVGISVVD 384
Cdd:PRK06370 322 NDAR-------------IVAANLLDGGRRKVSDRIVPYATYT-DPPLARVGMTEAEARKSGRrvlvgtrpmtRVGRAVEK 387

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 385 DNDRpEFMgsydkvrfKLVYDKKTLRILGAQLLSwnTNHSEIIFYIALAIQKQMLLTELG 444
Cdd:PRK06370 388 GETQ-GFM--------KVVVDADTDRILGATILG--VHGDEMIHEILDAMYAGAPYTTLS 436
PRK06116 PRK06116
glutathione reductase; Validated
 106-434 9.45e-14

glutathione reductase; Validated


Pssm-ID: 235701 [Multi-domain]  Cd Length: 450  Bit Score: 72.88  E-value: 9.45e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 106 DQLVIASGAWPICMNVENKvthkplefnytdkycgnvknliscklyQHALTLIDSFRKDKTIKSVAIVGSGYIGLELA-- 183
Cdd:PRK06116 133 DHILIATGGRPSIPDIPGA---------------------------EYGITSDGFFALEELPKRVAVVGAGYIAVEFAgv 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 184 ------EAAWLCKKqvtvidllDKPAgNNFDHEFTDELEKVMQKDGLKLMMGCSVKGfVVDSTNNVVKGVETDKGIVNAD 257
Cdd:PRK06116 186 lnglgsETHLFVRG--------DAPL-RGFDPDIRETLVEEMEKKGIRLHTNAVPKA-VEKNADGSLTLTLEDGETLTVD 255

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 258 LVIQSIGFRPSTKFVPKDQ-NFEFIHNGSIKVNEFlQALNHKDVYVIGGCAAiynaaseqyeNIDLATNAVKSGLVAAMH 336
Cdd:PRK06116 256 CLIWAIGREPNTDGLGLENaGVKLNEKGYIIVDEY-QNTNVPGIYAVGDVTG----------RVELTPVAIAAGRRLSER 324

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 337 IIGSNQV-KLQ-SIVGTNalhIFGL-NLAACGLTEQRAKKLGFDVGISVVDDNDRPefM-----GSYDKVRFKLVYDKKT 408
Cdd:PRK06116 325 LFNNKPDeKLDySNIPTV---VFSHpPIGTVGLTEEEAREQYGEDNVKVYRSSFTP--MytaltGHRQPCLMKLVVVGKE 399

                        330       340
                 ....*....|....*....|....*.
gi 497571723 409 LRILGAQLLSWNTnhSEIIFYIALAI 434
Cdd:PRK06116 400 EKVVGLHGIGFGA--DEMIQGFAVAI 423
Pyr_redox_dim pfam02852
Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; This family includes both ...
 357-454 4.16e-13

Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases.


Pssm-ID: 427019 [Multi-domain]  Cd Length: 109  Bit Score: 65.27  E-value: 4.16e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  357 FGLNLAACGLTEQRAKKLGFD--VGISVVDDNDRPEFMGSyDKVRFKLVYDKKTLRILGAQLLSwnTNHSEIIFYIALAI 434
Cdd:pfam02852   7 TDPEIASVGLTEEEAKEKGGEvkVGKFPFAANGRALAYGD-TDGFVKLVADRETGKILGAHIVG--PNAGELIQEAALAI 83

                          90       100
                  ....*....|....*....|
gi 497571723  435 QKQMLLTELGLvDVYFLPHY 454
Cdd:pfam02852  84 KMGATVEDLAN-TIHIHPTL 102
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 169-245 7.42e-12

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 61.07  E-value: 7.42e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497571723  169 SVAIVGSGYIGLELAEAawLCK--KQVTVIDLLDKPaGNNFDHEFTDELEKVMQKDGLKLMMGCSVKGFVVDSTNNVVK 245
Cdd:pfam00070   1 RVVVVGGGYIGLELAGA--LARlgSKVTVVERRDRL-LPGFDPEIAKILQEKLEKNGIEFLLNTTVEAIEGNGDGVVVV 76
PRK04965 PRK04965
NADH:flavorubredoxin reductase NorW;
80-309 2.08e-11

NADH:flavorubredoxin reductase NorW;


Pssm-ID: 179902 [Multi-domain]  Cd Length: 377  Bit Score: 65.32  E-value: 2.08e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  80 VTNIDLIKKQVTVRDltsnKEFtdQFDQLVIASGAWPICmnvenkvthKPLEFNytdkycGNVKNLISCKLYQHALTLID 159
Cdd:PRK04965  81 VTDIDAEAQVVKSQG----NQW--QYDKLVLATGASAFV---------PPIPGR------ELMLTLNSQQEYRAAETQLR 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 160 SfrkdktIKSVAIVGSGYIGLELAEAawLCK--KQVTVIDLLDKPAGNNFDHEFTDELEKVMQKDGLKLMMGCSVKGfvV 237
Cdd:PRK04965 140 D------AQRVLVVGGGLIGTELAMD--LCRagKAVTLVDNAASLLASLMPPEVSSRLQHRLTEMGVHLLLKSQLQG--L 209

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497571723 238 DSTNNVVKgVETDKG-IVNADLVIQSIGFRPSTKfVPKDQNFEfIHNGsIKVNEFLQAlNHKDVYVIGGCAAI 309
Cdd:PRK04965 210 EKTDSGIR-ATLDSGrSIEVDAVIAAAGLRPNTA-LARRAGLA-VNRG-IVVDSYLQT-SAPDIYALGDCAEI 277
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
65-337 6.41e-11

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 63.22  E-value: 6.41e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  65 EELKQMGANIFMSHdVTNIDLIKKQVTVRdLTSNKEFTdqFDQLVIASGAwpicmnvenkvTHKPLEFNYTDKYCGnvKN 144
Cdd:COG0492   65 EQAERFGAEILLEE-VTSVDKDDGPFRVT-TDDGTEYE--AKAVIIATGA-----------GPRKLGLPGEEEFEG--RG 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 145 LISCKLYQHAltlidsFRKDKTiksVAIVGSGYIGLE----LAEAAwlckKQVTVIDLLDKPAGnnfdhefTDEL-EKVM 219
Cdd:COG0492  128 VSYCATCDGF------FFRGKD---VVVVGGGDSALEealyLTKFA----SKVTLIHRRDELRA-------SKILvERLR 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 220 QKDGLKLMMGCSVKGFVVDstnNVVKGVETDKG------IVNADLVIQSIGFRPSTKFVpKDQNFEFIHNGSIKVNEFLQ 293
Cdd:COG0492  188 ANPKIEVLWNTEVTEIEGD---GRVEGVTLKNVktgeekELEVDGVFVAIGLKPNTELL-KGLGLELDEDGYIVVDEDME 263

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 497571723 294 AlNHKDVYVIGGCAAiynaaseqyENIDLATNAVKSGLVAAMHI 337
Cdd:COG0492  264 T-SVPGVFAAGDVRD---------YKYRQAATAAGEGAIAALSA 297
PTZ00058 PTZ00058
glutathione reductase; Provisional
 159-371 3.82e-10

glutathione reductase; Provisional


Pssm-ID: 185420 [Multi-domain]  Cd Length: 561  Bit Score: 61.94  E-value: 3.82e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 159 DSFRKDKTIKSVAIVGSGYIGLELAEAAWLCKKQVTVIDLLDKpAGNNFDHEFTDELEKVMQKDGLKLMMGCSVKGFVVD 238
Cdd:PTZ00058 229 DDFFKIKEAKRIGIAGSGYIAVELINVVNRLGAESYIFARGNR-LLRKFDETIINELENDMKKNNINIITHANVEEIEKV 307

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 239 STNNVVKGVETDKGIVNADLVIQSIGFRPSTKFVPKDQNFEFIHNGSIKVNEFlQALNHKDVYVIGGCAAIY-------- 310
Cdd:PTZ00058 308 KEKNLTIYLSDGRKYEHFDYVIYCVGRSPNTEDLNLKALNIKTPKGYIKVDDN-QRTSVKHIYAVGDCCMVKknqeiedl 386

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 311 ----------------NAASEQYENIDLATNAVKSGLVAAMHIIG-----SNQVKLQSIVGTNAlhifglNLAACGLTEQ 369
Cdd:PTZ00058 387 nllklyneepylkkkeNTSGESYYNVQLTPVAINAGRLLADRLFGpfsrtTNYKLIPSVIFSHP------PIGTIGLSEQ 460


                 ..
gi 497571723 370 RA 371
Cdd:PTZ00058 461 EA 462
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 67-337 3.90e-10

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 61.69  E-value: 3.90e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  67 LKQMGANIFMSHDVTnidlikKQVTVRDLTsnkeftDQFDQLVIASGAW-PICMNVENK----VtHKPLEFnytdkycgn 141
Cdd:COG0493  181 IEALGVEFRTNVEVG------KDITLDELL------EEFDAVFLATGAGkPRDLGIPGEdlkgV-HSAMDF--------- 238

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 142 vknLISCKLYQHALTLIdsfrkdKTIKSVAIVGSGYIGLELAEAAW-LCKKQVTVIDLLDK---PAgnnFDHEFTDELEk 217
Cdd:COG0493  239 ---LTAVNLGEAPDTIL------AVGKRVVVIGGGNTAMDCARTALrLGAESVTIVYRRTReemPA---SKEEVEEALE- 305

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 218 vmqkDGLKLMMGCSVKGFVVDStNNVVKGVETDK---------G------------IVNADLVIQSIGFRPSTKFVPKDQ 276
Cdd:COG0493  306 ----EGVEFLFLVAPVEIIGDE-NGRVTGLECVRmelgepdesGrrrpvpiegsefTLPADLVILAIGQTPDPSGLEEEL 380

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497571723 277 NFEFIHNGSIKVNEFLQALNHKDVYVIGGCAaiyNAASeqyenidLATNAVKSGLVAAMHI 337
Cdd:COG0493  381 GLELDKRGTIVVDEETYQTSLPGVFAGGDAV---RGPS-------LVVWAIAEGRKAARAI 431
nitri_red_nirB TIGR02374
nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen ...
 4-365 1.13e-09

nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen metabolism]


Pssm-ID: 162827 [Multi-domain]  Cd Length: 785  Bit Score: 60.61  E-value: 1.13e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723    4 VIVIGINHAGTSFIRTLLSKSKD-FKVNAYDRNTNISFLGCGIALAVSGVvKNTDDLFYSNPEELKQMGANIFMSHDVTN 82
Cdd:TIGR02374   1 LVLVGNGMAGHRCIEEVLKLNRHmFEITIFGEEPHPNYNRILLSSVLQGE-ADLDDITLNSKDWYEKHGITLYTGETVIQ 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723   83 IDLIKKQVtvrdLTSNKEfTDQFDQLVIASGAWPICMNVenKVTHKPLEFNYTDkyCGNVKNLISCKlyqhaltlidsfr 162
Cdd:TIGR02374  80 IDTDQKQV----ITDAGR-TLSYDKLILATGSYPFILPI--PGADKKGVYVFRT--IEDLDAIMAMA------------- 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  163 kdKTIKSVAIVGSGYIGLELAEAAWLCKKQVTVIDLLDKPAGNNFDHEFTDELEKVMQKDGLKLMMGcsvKGFVVDSTNN 242
Cdd:TIGR02374 138 --QRFKKAAVIGGGLLGLEAAVGLQNLGMDVSVIHHAPGLMAKQLDQTAGRLLQRELEQKGLTFLLE---KDTVEIVGAT 212

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  243 VVKGVE-TDKGIVNADLVIQSIGFRPSTKFVPKDQnfeFIHNGSIKVNEFLQAlNHKDVYVIGGCAAIYNAAseqyenID 321
Cdd:TIGR02374 213 KADRIRfKDGSSLEADLIVMAAGIRPNDELAVSAG---IKVNRGIIVNDSMQT-SDPDIYAVGECAEHNGRV------YG 282

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 497571723  322 LATNAVKSGLVAAMHIIGSNQVKLQSIVGTNALHIFGLNLAACG 365
Cdd:TIGR02374 283 LVAPLYEQAKVLADHICGVECEEYEGSDLSAKLKLLGVDVWSAG 326
PRK06327 PRK06327
dihydrolipoamide dehydrogenase; Validated
 168-434 1.37e-08

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235779 [Multi-domain]  Cd Length: 475  Bit Score: 56.86  E-value: 1.37e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 168 KSVAIVGSGYIGLELAEAAWLCKKQVTVIDLLDKPAGNNfDHEFTDELEKVMQKDGLKLMMGCSVkGFVVDSTNNVVKGV 247
Cdd:PRK06327 184 KKLAVIGAGVIGLELGSVWRRLGAEVTILEALPAFLAAA-DEQVAKEAAKAFTKQGLDIHLGVKI-GEIKTGGKGVSVAY 261

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 248 ETDKGIVN---ADLVIQSIGFRPSTkfvpKDQNFEFI-----HNGSIKVNEFLQAlNHKDVYVIGGCAA---IYNAASEQ 316
Cdd:PRK06327 262 TDADGEAQtleVDKLIVSIGRVPNT----DGLGLEAVglkldERGFIPVDDHCRT-NVPNVYAIGDVVRgpmLAHKAEEE 336

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 317 yenidlatnavksGLVAAMHIIGSNqvklqSIVGTNALH--IFGL-NLAACGLTEQRAKKLG--FDVGISVVDDNDRPEF 391
Cdd:PRK06327 337 -------------GVAVAERIAGQK-----GHIDYNTIPwvIYTSpEIAWVGKTEQQLKAEGveYKAGKFPFMANGRALA 398

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 497571723 392 MGSYDKvrF-KLVYDKKTLRILGAQLLSWNTnhSEIIFYIALAI 434
Cdd:PRK06327 399 MGEPDG--FvKIIADAKTDEILGVHVIGPNA--SELIAEAVVAM 438
PRK14989 PRK14989
nitrite reductase subunit NirD; Provisional
 3-417 2.03e-08

nitrite reductase subunit NirD; Provisional


Pssm-ID: 184951 [Multi-domain]  Cd Length: 847  Bit Score: 56.67  E-value: 2.03e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723   3 KVIVIGINHAGTSFIRTLLSKS--KDFKVN--------AYDRNTNISFLGCGIALAVSgVVKNTddlFYsnpeelKQMGA 72
Cdd:PRK14989   5 RLAIIGNGMVGHRFIEDLLDKAdaANFDITvfceepriAYDRVHLSSYFSHHTAEELS-LVREG---FY------EKHGI 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  73 NIFMSHDVTNIDLIKKQVTvrdltSNKEFTDQFDQLVIASGAWPICMNVENKVTHkplefnytdkycgnvknliSCKLYQ 152
Cdd:PRK14989  75 KVLVGERAITINRQEKVIH-----SSAGRTVFYDKLIMATGSYPWIPPIKGSETQ-------------------DCFVYR 130

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 153 --HALTLIDSFRKDKtiKSVAIVGSGYIGLELAEAAWLCKKQVTVIDLLDKPAGNNFDHEFTDELEKVMQKDGLKLMMGC 230
Cdd:PRK14989 131 tiEDLNAIEACARRS--KRGAVVGGGLLGLEAAGALKNLGVETHVIEFAPMLMAEQLDQMGGEQLRRKIESMGVRVHTSK 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 231 SVKGFVVDSTNNVVKGVETDKGIVNADLVIQSIGFRPSTKFVpKDQNFEFIHNGSIKVNEFLQAlNHKDVYVIGGCaaiy 310
Cdd:PRK14989 209 NTLEIVQEGVEARKTMRFADGSELEVDFIVFSTGIRPQDKLA-TQCGLAVAPRGGIVINDSCQT-SDPDIYAIGEC---- 282

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 311 naASEQYENIDLATNAVKSGLVAAMHIIGSNqvklqsivgtNALHifGLNLAAcglteqRAKKLGFDVGiSVVDDNDRPE 390
Cdd:PRK14989 283 --ASWNNRVFGLVAPGYKMAQVAVDHLLGSE----------NAFE--GADLSA------KLKLLGVDVG-GIGDAHGRTP 341

                        410       420       430
                 ....*....|....*....|....*....|...
gi 497571723 391 FMGSY------DKVRFKLVYDKKTLRILGAQLL 417
Cdd:PRK14989 342 GARSYvyldesKEIYKRLIVSEDNKTLLGAVLV 374
PTZ00318 PTZ00318
NADH dehydrogenase-like protein; Provisional
 75-337 4.11e-08

NADH dehydrogenase-like protein; Provisional


Pssm-ID: 185553 [Multi-domain]  Cd Length: 424  Bit Score: 55.16  E-value: 4.11e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  75 FMSHDVTNIDLIKKQVTVRDLTSN-----KEFTDQFDQLVIASGAWPICMNVENkVTHKPLEFNYTDKYCGNVKNLISCk 149
Cdd:PTZ00318  79 YLRAVVYDVDFEEKRVKCGVVSKSnnanvNTFSVPYDKLVVAHGARPNTFNIPG-VEERAFFLKEVNHARGIRKRIVQC- 156

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 150 lYQHALTLIDSFRKDKTIKSVAIVGSGYIGLELA----------------EAAWLCKkqVTVIDLLDKPAGNnFDHEFTD 213
Cdd:PTZ00318 157 -IERASLPTTSVEERKRLLHFVVVGGGPTGVEFAaeladffrddvrnlnpELVEECK--VTVLEAGSEVLGS-FDQALRK 232

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 214 ELEKVMQKDGLKLMMGCSVKGfVVDstnnvvKGVETDKG-IVNADLVIQSIGFRPSTkfVPKDQNFEFIHNGSIKVNEFL 292
Cdd:PTZ00318 233 YGQRRLRRLGVDIRTKTAVKE-VLD------KEVVLKDGeVIPTGLVVWSTGVGPGP--LTKQLKVDKTSRGRISVDDHL 303

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 497571723 293 QALNHKDVYVIGGCAAIynaaseqyENIDLATNAV---KSGLVAAMHI 337
Cdd:PTZ00318 304 RVKPIPNVFALGDCAAN--------EERPLPTLAQvasQQGVYLAKEF 343
trypano_reduc TIGR01423
trypanothione-disulfide reductase; Trypanothione, a glutathione-modified derivative of ...
 87-435 3.21e-07

trypanothione-disulfide reductase; Trypanothione, a glutathione-modified derivative of spermidine, is (in its reduced form) an important antioxidant found in trypanosomatids (Crithidia, Leishmania, Trypanosoma). This model describes trypanothione reductase, a possible antitrypanosomal drug target closely related to some forms of glutathione reductase.


Pssm-ID: 200098 [Multi-domain]  Cd Length: 486  Bit Score: 52.67  E-value: 3.21e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723   87 KKQVTVR---DLTSNKEFTDQFDQLVIASGAWPICMNVENKvthkplefnytdkycgnvknliscklyQHALTLIDSFRK 163
Cdd:TIGR01423 131 KNVVLVResaDPKSAVKERLQAEHILLATGSWPQMLGIPGI---------------------------EHCISSNEAFYL 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  164 DKTIKSVAIVGSGYIGLELAEAAWLCKKQVTVIDLL--DKPAGNNFDHEFTDELEKVMQKDGLKLMMGCSVKGFVV--DS 239
Cdd:TIGR01423 184 DEPPRRVLTVGGGFISVEFAGIFNAYKPRGGKVTLCyrNNMILRGFDSTLRKELTKQLRANGINIMTNENPAKVTLnaDG 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  240 TNNVV--KGVETDkgivnADLVIQSIGFRPSTKFVPKDQ-NFEFIHNGSIKVNEFLQAlNHKDVYVIGGCAaiynaaseq 316
Cdd:TIGR01423 264 SKHVTfeSGKTLD-----VDVVMMAIGRVPRTQTLQLDKvGVELTKKGAIQVDEFSRT-NVPNIYAIGDVT--------- 328

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  317 yENIDLATNAVKSGLVAAMHIIGSNQVKLQSIVGTNAlhIFGL-NLAACGLTEQRAKKlGFDvGISVVDDNDRP---EFM 392
Cdd:TIGR01423 329 -DRVMLTPVAINEGAAFVDTVFGNKPRKTDHTRVASA--VFSIpPIGTCGLVEEDAAK-KFE-KVAVYESSFTPlmhNIS 403

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 497571723  393 GS-YDKVRFKLVYDKKTLRILGAQLLSwnTNHSEIIFYIALAIQ 435
Cdd:TIGR01423 404 GSkYKKFVAKIVTNHADGTVLGVHLLG--DSSPEIIQAVGICLK 445
PRK08010 PRK08010
pyridine nucleotide-disulfide oxidoreductase; Provisional
 170-417 3.38e-06

pyridine nucleotide-disulfide oxidoreductase; Provisional


Pssm-ID: 181196 [Multi-domain]  Cd Length: 441  Bit Score: 49.24  E-value: 3.38e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 170 VAIVGSGYIGLELAEAAWLCKKQVTVIDlldkpAGNNF----DHEFTDELEKVMQKDGLKLMMGCSVKGfvVDSTNNVVK 245
Cdd:PRK08010 161 LGILGGGYIGVEFASMFANFGSKVTILE-----AASLFlpreDRDIADNIATILRDQGVDIILNAHVER--ISHHENQVQ 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 246 gVETDKGIVNADLVIQSIGFRPSTKFV-PKDQNFEFIHNGSIKVNEFLQAlNHKDVYVIGGCaaiynAASEQYENIDLAT 324
Cdd:PRK08010 234 -VHSEHAQLAVDALLIASGRQPATASLhPENAGIAVNERGAIVVDKYLHT-TADNIWAMGDV-----TGGLQFTYISLDD 306

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 325 -NAVKSGLVAAmhiiGSNQVKLQSIVGTNALhiFGLNLAACGLTEQRAKKLGFDVGISV--VDDNDRPEFMGSYDKVrFK 401
Cdd:PRK08010 307 yRIVRDELLGE----GKRSTDDRKNVPYSVF--MTPPLSRVGMTEEQARESGADIQVVTlpVAAIPRARVMNDTRGV-LK 379

                        250
                 ....*....|....*.
gi 497571723 402 LVYDKKTLRILGAQLL 417
Cdd:PRK08010 380 AIVDNKTQRILGASLL 395
PRK13748 PRK13748
putative mercuric reductase; Provisional
 171-443 6.87e-06

putative mercuric reductase; Provisional


Pssm-ID: 184298 [Multi-domain]  Cd Length: 561  Bit Score: 48.61  E-value: 6.87e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 171 AIVGSGYIGLELAEAAWLCKKQVTVI---DLL--DKPAgnnfdheFTDELEKVMQKDGLKLMMGCSVKGFVVDSTNNVVk 245
Cdd:PRK13748 274 AVIGSSVVALELAQAFARLGSKVTILarsTLFfrEDPA-------IGEAVTAAFRAEGIEVLEHTQASQVAHVDGEFVL- 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 246 gvETDKGIVNADLVIQSIGFRPSTKFVPKDQ-NFEFIHNGSIKVNEFLQAlNHKDVYVIGGCAA----IYNAASeqyeni 320
Cdd:PRK13748 346 --TTGHGELRADKLLVATGRAPNTRSLALDAaGVTVNAQGAIVIDQGMRT-SVPHIYAAGDCTDqpqfVYVAAA------ 416

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 321 dlatnavkSGLVAAMHIIGS----NQVKLQSIVGTNAlhifglNLAACGLTEQRAKKLGFDVGISVVDDNDRPEFMGSYD 396
Cdd:PRK13748 417 --------AGTRAAINMTGGdaalDLTAMPAVVFTDP------QVATVGYSEAEAHHDGIETDSRTLTLDNVPRALANFD 482

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 497571723 397 KVRF-KLVYDKKTLRILGAQLLSwnTNHSEIIFYIALAIQKQMLLTEL 443
Cdd:PRK13748 483 TRGFiKLVIEEGSGRLIGVQAVA--PEAGELIQTAALAIRNRMTVQEL 528
PRK07251 PRK07251
FAD-containing oxidoreductase;
168-443 9.43e-06

FAD-containing oxidoreductase;


Pssm-ID: 180907 [Multi-domain]  Cd Length: 438  Bit Score: 47.82  E-value: 9.43e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 168 KSVAIVGSGYIGLELAEAAWLCKKQVTVIDLLDKPAGNnfDHEFTDELEK-VMQKDGLKLMMGCSVKGfVVDSTNNVVkg 246
Cdd:PRK07251 158 ERLGIIGGGNIGLEFAGLYNKLGSKVTVLDAASTILPR--EEPSVAALAKqYMEEDGITFLLNAHTTE-VKNDGDQVL-- 232

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 247 VETDKGIVNADLVIQSIGFRPSTKFVP-KDQNFEFIHNGSIKVNEFLQAlNHKDVYVIGGCaaiynAASEQYENIDLATN 325
Cdd:PRK07251 233 VVTEDETYRFDALLYATGRKPNTEPLGlENTDIELTERGAIKVDDYCQT-SVPGVFAVGDV-----NGGPQFTYISLDDF 306

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 326 AVKSGLVAAMhiiGSNQVKLQSIVGTNALhifgLN--LAACGLTEQRAKKLGFDVGISVVDDNDRPE-FMGSYDKVRFKL 402
Cdd:PRK07251 307 RIVFGYLTGD---GSYTLEDRGNVPTTMF----ITppLSQVGLTEKEAKEAGLPYAVKELLVAAMPRaHVNNDLRGAFKV 379

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 497571723 403 VYDKKTLRILGAQLLSWNTNhsEIIFYIALAIQKQMLLTEL 443
Cdd:PRK07251 380 VVNTETKEILGATLFGEGSQ--EIINLITMAMDNKIPYTYF 418
PRK09754 PRK09754
phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional
 168-264 2.48e-04

phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional


Pssm-ID: 170080 [Multi-domain]  Cd Length: 396  Bit Score: 43.38  E-value: 2.48e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 168 KSVAIVGSGYIGLELAEAAWLCKKQVTVIDLLDKPAGNNFDHEFTDELEKVMQKDGLKLMMGCSVKGfVVDSTNNVVKGV 247
Cdd:PRK09754 145 RSVVIVGAGTIGLELAASATQRRCKVTVIELAATVMGRNAPPPVQRYLLQRHQQAGVRILLNNAIEH-VVDGEKVELTLQ 223

                         90
                 ....*....|....*..
gi 497571723 248 ETDKgiVNADLVIQSIG 264
Cdd:PRK09754 224 SGET--LQADVVIYGIG 238
TGR TIGR01438
thioredoxin and glutathione reductase selenoprotein; This homodimeric, FAD-containing member ...
 172-371 1.01e-03

thioredoxin and glutathione reductase selenoprotein; This homodimeric, FAD-containing member of the pyridine nucleotide disulfide oxidoreductase family contains a C-terminal motif Cys-SeCys-Gly, where SeCys is selenocysteine encoded by TGA (in some sequence reports interpreted as a stop codon). In some members of this subfamily, Cys-SeCys-Gly is replaced by Cys-Cys-Gly. The reach of the selenium atom at the C-term arm of the protein is proposed to allow broad substrate specificity.


Pssm-ID: 273624 [Multi-domain]  Cd Length: 484  Bit Score: 41.38  E-value: 1.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  172 IVGSGYIGLELAEAAWLCKKQVTVidLLDKPAGNNFDHEFTDELEKVMQKDGLKLMMGCSVKGFVVDSTNNVVKGVETDK 251
Cdd:TIGR01438 185 VVGASYVALECAGFLAGIGLDVTV--MVRSILLRGFDQDCANKVGEHMEEHGVKFKRQFVPIKVEQIEAKVLVEFTDSTN 262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  252 GIVNA-DLVIQSIGFRPSTKFVpkdqNFEFI------HNGSIKVNEFLQAlNHKDVYVIGGCAAiynaaseqyENIDLAT 324
Cdd:TIGR01438 263 GIEEEyDTVLLAIGRDACTRKL----NLENVgvkinkKTGKIPADEEEQT-NVPYIYAVGDILE---------DKPELTP 328

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 497571723  325 NAVKSGLVAAMHIIGSNQVKLQ-SIVGTNalhIFG-LNLAACGLTEQRA 371
Cdd:TIGR01438 329 VAIQAGRLLAQRLFKGSTVICDyENVPTT---VFTpLEYGACGLSEEKA 374
PRK13984 PRK13984
putative oxidoreductase; Provisional
 154-293 3.26e-03

putative oxidoreductase; Provisional


Pssm-ID: 172486 [Multi-domain]  Cd Length: 604  Bit Score: 40.14  E-value: 3.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 154 ALTLIDSFR--------KDKTIKSVAIVGSGYIGLELAEAAWLCKKQ------VTVIDLldkpaGNNFDHEFTDELEKV- 218
Cdd:PRK13984 397 ALPLLREIRdylrgegpKPKIPRSLVVIGGGNVAMDIARSMARLQKMeygevnVKVTSL-----ERTFEEMPADMEEIEe 471

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 219 MQKDGLKLMMGCSVKGFVVDstNNVVKGV--------------------ETDKGIVNADLVIQSIGFRPSTKFVPKD--Q 276
Cdd:PRK13984 472 GLEEGVVIYPGWGPMEVVIE--NDKVKGVkfkkcvevfdeegrfnpkfdESDQIIVEADMVVEAIGQAPDYSYLPEElkS 549

                        170
                 ....*....|....*..
gi 497571723 277 NFEFIHnGSIKVNEFLQ 293
Cdd:PRK13984 550 KLEFVR-GRILTNEYGQ 565
Pyr_redox_3 pfam13738
Pyridine nucleotide-disulphide oxidoreductase;
200-330 4.49e-03

Pyridine nucleotide-disulphide oxidoreductase;


Pssm-ID: 404603 [Multi-domain]  Cd Length: 296  Bit Score: 39.13  E-value: 4.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723  200 DKPAGNnfdhEFTDELEKVMQKDGLKLMMGCSVKGfvVDSTNNVVKgVETDKGIVNADLVIQSIGFrpstkF-VPKDQNF 278
Cdd:pfam13738  70 EHPSGN----EYAEYLRRVADHFELPINLFEEVTS--VKKEDDGFV-VTTSKGTYQARYVIIATGE-----FdFPNKLGV 137

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 497571723  279 EF--IHNGsiKVNEFLQaLNHKDVYVIGGcaaiYNAAseqyenIDLATNAVKSG 330
Cdd:pfam13738 138 PElpKHYS--YVKDFHP-YAGQKVVVIGG----YNSA------VDAALELVRKG 178
trkA PRK09496
Trk system potassium transporter TrkA;
162-224 5.28e-03

Trk system potassium transporter TrkA;


Pssm-ID: 236541 [Multi-domain]  Cd Length: 453  Bit Score: 39.34  E-value: 5.28e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497571723 162 RKDKTIKSVAIVGSGYIGLELAEAawLCKK--QVTVIDlldkpagNNFDH--EFTDELEK--VMQKDGL 224
Cdd:PRK09496 226 RLEKPVKRVMIVGGGNIGYYLAKL--LEKEgySVKLIE-------RDPERaeELAEELPNtlVLHGDGT 285
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 162-337 9.41e-03

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 38.32  E-value: 9.41e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 162 RKDKTIKSVAIVGSGYIGLELAEAAWLCK-KQVTVI---DLLDKPAgnnFDHEFTDELEkvmqkDGLKLMMGCSVKGFVV 237
Cdd:PRK12771 262 EPPFLGKRVVVIGGGNTAMDAARTARRLGaEEVTIVyrrTREDMPA---HDEEIEEALR-----EGVEINWLRTPVEIEG 333

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497571723 238 DSTNN-------VVKGVETDKG----------IVNADLVIQSIGFRPSTKFVPKDQNFEfIHNGSIKVNEFLQALNHKDV 300
Cdd:PRK12771 334 DENGAtglrvitVEKMELDEDGrpspvtgeeeTLEADLVVLAIGQDIDSAGLESVPGVE-VGRGVVQVDPNFMMTGRPGV 412

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 497571723 301 YVIGGCAaiynaaseqyENIDLATNAVKSGLVAAMHI 337
Cdd:PRK12771 413 FAGGDMV----------PGPRTVTTAIGHGKKAARNI 439
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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