|
Name |
Accession |
Description |
Interval |
E-value |
| COG5001 |
COG5001 |
Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain ... |
6-682 |
0e+00 |
|
Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain [Signal transduction mechanisms];
Pssm-ID: 444025 [Multi-domain] Cd Length: 678 Bit Score: 668.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 6 YNQVLVAFSLIVAILASYTALDMAGRVTLAKGREALSWLIGGAFAMGFGIWSMHFVGMLAFSLPIPLGYDLGLTLLSLLL 85
Cdd:COG5001 1 LLALAALLLLLLALLLALLLLALLLLALLLAALLALALLLLLLLLLLALLLAALLLLALLALLALLLLAAALLALALAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 86 AVGSSAFALWLVCQAELPWQRLALGALLMGSGIAAMHYTGMAALLMMPGIVYDPLWLGLSILIAVIASGAALWIAFRLRH 165
Cdd:COG5001 81 LLAALLAALLLLLLLLLALLVLLLLLLLLLALLALLAALLARALAALLLAAASAALLAAALGAALLAALALALLLALARA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 166 GSRRIVLVRAGAALVMgcaivgmHYTGMAAAQFPLGSFCGAAGRGIDNGWLAVLVIVITLAVIAIALIVSVLDSRLEART 245
Cdd:COG5001 161 LLALLLLLLLALLLLL-------LLLLLLALLLLLLLALLLRLLLLLRGGRLLRLALRLLLGLLLLGLLLLLLLVAVLAI 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 246 SVLATSLARANRELIQLALHDNLTKLPNRMLLDDRLEQAIQQAIRDDRRFAVLFMDLDGFKAVNDAYGHHLGDLLLIEVA 325
Cdd:COG5001 234 ARLITERKRAEERLRHLAYHDPLTGLPNRRLFLDRLEQALARARRSGRRLALLFIDLDRFKEINDTLGHAAGDELLREVA 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 326 ERIRANVRAQDTIARLGGDEFVLLIE-AREPADAATLAEKLVKRISQPYQISRHEVRISASIGIALYPGDGQTRHELMIN 404
Cdd:COG5001 314 RRLRACLREGDTVARLGGDEFAVLLPdLDDPEDAEAVAERILAALAEPFELDGHELYVSASIGIALYPDDGADAEELLRN 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 405 ADAAMYHAKDQGRNGYCFFESSMNANAQEQLQLLHDLRQALERRQLVLHYQPKVLAPNGPMIGVEALLRWEHPQHGLITP 484
Cdd:COG5001 394 ADLAMYRAKAAGRNRYRFFDPEMDERARERLELEADLRRALERGELELHYQPQVDLATGRIVGAEALLRWQHPERGLVSP 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 485 GQFLPLAEKTGLIVQIGEWVLDEACRQMRLWLDGGHAEWNIAVNLSALQFAHAGLVDSVRNALLRHSLEPSHLILEVTES 564
Cdd:COG5001 474 AEFIPLAEETGLIVPLGEWVLREACRQLAAWQDAGLPDLRVAVNLSARQLRDPDLVDRVRRALAETGLPPSRLELEITES 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 565 TAMRDADASLVILEQLSAMGVGISIDDFGTGYSSLLYLKRLPASELKIDRGFINELAHDSDDAAIVSAIVALGRTLNLKI 644
Cdd:COG5001 554 ALLEDPEEALETLRALRALGVRIALDDFGTGYSSLSYLKRLPVDTLKIDRSFVRDLAEDPDDAAIVRAIIALAHSLGLEV 633
|
650 660 670
....*....|....*....|....*....|....*...
gi 497562044 645 VAEGVETEAQQEFLTRLGCNSLQGFLLGRPMPAEQLLA 682
Cdd:COG5001 634 VAEGVETEEQLEFLRELGCDYAQGYLFSRPLPAEELEA 671
|
|
| PRK10060 |
PRK10060 |
cyclic di-GMP phosphodiesterase; |
254-680 |
5.74e-132 |
|
cyclic di-GMP phosphodiesterase;
Pssm-ID: 236645 [Multi-domain] Cd Length: 663 Bit Score: 404.06 E-value: 5.74e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 254 RANRELIQLALHDNLTKLPNRMLLDDRLEQAIQQaiRDDRRFAVLFMDLDGFKAVNDAYGHHLGDLLLIEVAERIRANVR 333
Cdd:PRK10060 228 RAQERLRILANTDSITGLPNRNAIQELIDHAINA--ADNNQVGIVYLDLDNFKKVNDAYGHMFGDQLLQDVSLAILSCLE 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 334 AQDTIARLGGDEFVLLIEAREPADAATLAEKLVKRISQPYQISRHEVRISASIGIALYPGDGQTRHELMINADAAMYHAK 413
Cdd:PRK10060 306 EDQTLARLGGDEFLVLASHTSQAALEAMASRILTRLRLPFRIGLIEVYTGCSIGIALAPEHGDDSESLIRSADTAMYTAK 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 414 DQGRNGYCFFESSMNANAQEQLQLLHDLRQALERRQLVLHYQPKVLApNGPMIGVEALLRWEHPQHGLITPGQFLPLAEK 493
Cdd:PRK10060 386 EGGRGQFCVFSPEMNQRVFEYLWLDTNLRKALENDQLVIHYQPKITW-RGEVRSLEALVRWQSPERGLIPPLEFISYAEE 464
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 494 TGLIVQIGEWVLDEACRQMRLWLDGGhAEWNIAVNLSALQFAHAGLVDSVRNALLRHSLEPSHLILEVTESTAMRDADAS 573
Cdd:PRK10060 465 SGLIVPLGRWVMLDVVRQVAKWRDKG-INLRVAVNVSARQLADQTIFTALKQALQELNFEYCPIDVELTESCLIENEELA 543
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 574 LVILEQLSAMGVGISIDDFGTGYSSLLYLKRLPASELKIDRGFINELAHDSDDAAIVSAIVALGRTLNLKIVAEGVETEA 653
Cdd:PRK10060 544 LSVIQQFSQLGAQVHLDDFGTGYSSLSQLARFPIDAIKLDQSFVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVETAK 623
|
410 420
....*....|....*....|....*..
gi 497562044 654 QQEFLTRLGCNSLQGFLLGRPMPAEQL 680
Cdd:PRK10060 624 EDAFLTKNGVNERQGFLFAKPMPAVAF 650
|
|
| EAL |
cd01948 |
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL ... |
439-679 |
2.59e-114 |
|
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.
Pssm-ID: 238923 [Multi-domain] Cd Length: 240 Bit Score: 342.99 E-value: 2.59e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 439 HDLRQALERRQLVLHYQPKVLAPNGPMIGVEALLRWEHPQHGLITPGQFLPLAEKTGLIVQIGEWVLDEACRQMRLWLDG 518
Cdd:cd01948 1 ADLRRALERGEFELYYQPIVDLRTGRIVGYEALLRWRHPEGGLISPAEFIPLAEETGLIVELGRWVLEEACRQLARWQAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 519 GHAeWNIAVNLSALQFAHAGLVDSVRNALLRHSLEPSHLILEVTESTAMRDADASLVILEQLSAMGVGISIDDFGTGYSS 598
Cdd:cd01948 81 GPD-LRLSVNLSARQLRDPDFLDRLLELLAETGLPPRRLVLEITESALIDDLEEALATLRRLRALGVRIALDDFGTGYSS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 599 LLYLKRLPASELKIDRGFINELAHDSDDAAIVSAIVALGRTLNLKIVAEGVETEAQQEFLTRLGCNSLQGFLLGRPMPAE 678
Cdd:cd01948 160 LSYLKRLPVDYLKIDRSFVRDIETDPEDRAIVRAIIALAHSLGLKVVAEGVETEEQLELLRELGCDYVQGYLFSRPLPAE 239
|
.
gi 497562044 679 Q 679
Cdd:cd01948 240 E 240
|
|
| EAL |
smart00052 |
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a ... |
439-679 |
1.52e-103 |
|
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a variety of bacteria.
Pssm-ID: 214491 [Multi-domain] Cd Length: 242 Bit Score: 315.70 E-value: 1.52e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 439 HDLRQALERRQLVLHYQPKVLAPNGPMIGVEALLRWEHPQHGLITPGQFLPLAEKTGLIVQIGEWVLDEACRQMRLWLDG 518
Cdd:smart00052 2 RELRQALENGQFLLYYQPIVSLRTGRLVGVEALIRWQHPEGGIISPDEFIPLAEETGLIVPLGRWVLEQACQQLAEWQAQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 519 GHAEWNIAVNLSALQFAHAGLVDSVRNALLRHSLEPSHLILEVTESTAMRDADASLVILEQLSAMGVGISIDDFGTGYSS 598
Cdd:smart00052 82 GPPPLLISINLSARQLISPDLVPRVLELLEETGLPPQRLELEITESVLLDDDESAVATLQRLRELGVRIALDDFGTGYSS 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 599 LLYLKRLPASELKIDRGFINELAHDSDDAAIVSAIVALGRTLNLKIVAEGVETEAQQEFLTRLGCNSLQGFLLGRPMPAE 678
Cdd:smart00052 162 LSYLKRLPVDLLKIDKSFVRDLQTDPEDEAIVQSIIELAQKLGLQVVAEGVETPEQLDLLRSLGCDYGQGYLFSRPLPLD 241
|
.
gi 497562044 679 Q 679
Cdd:smart00052 242 D 242
|
|
| T2SS_HK |
NF038348 |
histidine kinase; |
5-259 |
1.77e-78 |
|
histidine kinase;
Pssm-ID: 439642 [Multi-domain] Cd Length: 574 Bit Score: 261.42 E-value: 1.77e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 5 SYNQVLVAFSLIVAILASYTALDMAGRVTLA-KGREALSWLIGGAFAMGFGIWSMHFVGMLAFSLPIPLGYDLGLTLLSL 83
Cdd:NF038348 4 TYDLSLVLLSLVIATLASYTALDLSALISLLdKPRLRRAWLAGGAAAMGTGIWAMHFVGMLAFSLPIPLGYDLRETGLSL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 84 LLAVGSSAFALWLVCQAELPWQRLALGALLMGSGIAAMHYTGMAALLMMPGIVYDPLWLGLSILIAVIASGAALWIAFRL 163
Cdd:NF038348 84 AIAMVVSYFALNAVTRAKLTRERLAAGGVLMGLGIAGMHYTGMAALQMQPGIRYDSALFVASIGIAILASTAALWLAHRL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 164 R-HGSRRIVLVRAGAALVMGCAIVGMHYTGMAAAQFPLGSFCGAAgRGIDNGWLAVLVIVITLAVIAIALIVSVLDSR-- 240
Cdd:NF038348 164 RtENAGRVIVKRIGAATVMGVAITGMHYTGMAAAHFAPNARCGAA-NGISGPWLGTTIALFTATILIVTLVISRFDARtm 242
|
250 260
....*....|....*....|
gi 497562044 241 -LEARTSVLATSLARANREL 259
Cdd:NF038348 243 fLRGITDALEDLVQLRTAEL 262
|
|
| EAL |
pfam00563 |
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL ... |
440-674 |
1.83e-78 |
|
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.
Pssm-ID: 425752 [Multi-domain] Cd Length: 235 Bit Score: 249.93 E-value: 1.83e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 440 DLRQALERRQLVLHYQPKVLAPNGPMIGVEALLRWEHPQHGLITPGQFLPLAEKTGLIVQIGEWVLDEACRQMRLWLDGG 519
Cdd:pfam00563 3 ALRRALENGEFVLYYQPIVDLRTGRVVGYEALLRWQHPDGGLISPARFLPLAEELGLIAELDRWVLEQALADLAQLQLGP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 520 HAewNIAVNLSALQFAHAGLVDSVRNALLRHSLEPSHLILEVTESTAMRDADASLVILEQLSAMGVGISIDDFGTGYSSL 599
Cdd:pfam00563 83 DI--KLSINLSPASLADPGFLELLRALLKQAGPPPSRLVLEITESDLLARLEALREVLKRLRALGIRIALDDFGTGYSSL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497562044 600 LYLKRLPASELKIDRGFINELAHDSDDAAIVSAIVALGRTLNLKIVAEGVETEAQQEFLTRLGCNSLQGFLLGRP 674
Cdd:pfam00563 161 SYLLRLPPDFVKIDRSLIADIDKDGEARAIVRALIALAHSLGIKVVAEGVETEEQLEALRELGCDLVQGYYFSKP 235
|
|
| GGDEF |
TIGR00254 |
diguanylate cyclase (GGDEF) domain; The GGDEF domain is named for the motif GG[DE]EF shared by ... |
262-420 |
1.39e-44 |
|
diguanylate cyclase (GGDEF) domain; The GGDEF domain is named for the motif GG[DE]EF shared by many proteins carrying the domain. There is evidence that the domain has diguanylate cyclase activity. Several proteins carrying this domain also carry domains with functions relating to environmental sensing. These include PleD, a response regulator protein involved in the swarmer-to-stalked cell transition in Caulobacter crescentus, and FixL, a heme-containing oxygen sensor protein. [Regulatory functions, Small molecule interactions, Signal transduction, Other]
Pssm-ID: 272984 [Multi-domain] Cd Length: 165 Bit Score: 157.11 E-value: 1.39e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 262 LALHDNLTKLPNRMLLDDRLEQAIQQAIRDDRRFAVLFMDLDGFKAVNDAYGHHLGDLLLIEVAERIRANVRAQDTIARL 341
Cdd:TIGR00254 1 QAVRDPLTGLYNRRYLEEMLDSELKRARRFQRSFSVLMIDIDNFKKINDTLGHDVGDEVLREVARILQSSVRGSDVVGRY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 342 GGDEFVLLIEAREPADAATLAEKLVKRISQ-PYQISRHE-VRISASIGIALYPGDGQTRHELMINADAAMYHAKDQGRNG 419
Cdd:TIGR00254 81 GGEEFVVILPGTPLEDALSKAERLRDAINSkPIEVAGSEtLTVTVSIGVACYPGHGLTLEELLKRADEALYQAKKAGRNR 160
|
.
gi 497562044 420 Y 420
Cdd:TIGR00254 161 V 161
|
|
| diguan_DgcJ |
NF040885 |
diguanylate cyclase DgcJ; |
266-417 |
6.58e-22 |
|
diguanylate cyclase DgcJ;
Pssm-ID: 468821 [Multi-domain] Cd Length: 490 Bit Score: 99.65 E-value: 6.58e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 266 DNLTKLPNRMLLDDRLEQAIQQAIRddRRFAVLFM--DLDGFKAVNDAYGHHLGDLLLIEVAERIRANVRAQDTIARLGG 343
Cdd:NF040885 344 DSMTGLYNRKILTPTLEQRLQRLTE--KGIPVTFIalDCDKLKHINDTLGHHEGDRAITLLAQAISASIRKSDYGIRLGG 421
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 497562044 344 DEF-VLLIEArEPADAAtlaeKLVKRISQPYQISRHEVRISASIGI-ALYPGDgqTRHELMINADAAMYHAKDQGR 417
Cdd:NF040885 422 DEFcIILIDY-EEAEAQ----NLIERIRQHLRTIDPDKRVSFSWGAyQMQPGD--TLDDAYKAADERLYLNKKQKH 490
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| COG5001 |
COG5001 |
Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain ... |
6-682 |
0e+00 |
|
Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain [Signal transduction mechanisms];
Pssm-ID: 444025 [Multi-domain] Cd Length: 678 Bit Score: 668.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 6 YNQVLVAFSLIVAILASYTALDMAGRVTLAKGREALSWLIGGAFAMGFGIWSMHFVGMLAFSLPIPLGYDLGLTLLSLLL 85
Cdd:COG5001 1 LLALAALLLLLLALLLALLLLALLLLALLLAALLALALLLLLLLLLLALLLAALLLLALLALLALLLLAAALLALALAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 86 AVGSSAFALWLVCQAELPWQRLALGALLMGSGIAAMHYTGMAALLMMPGIVYDPLWLGLSILIAVIASGAALWIAFRLRH 165
Cdd:COG5001 81 LLAALLAALLLLLLLLLALLVLLLLLLLLLALLALLAALLARALAALLLAAASAALLAAALGAALLAALALALLLALARA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 166 GSRRIVLVRAGAALVMgcaivgmHYTGMAAAQFPLGSFCGAAGRGIDNGWLAVLVIVITLAVIAIALIVSVLDSRLEART 245
Cdd:COG5001 161 LLALLLLLLLALLLLL-------LLLLLLALLLLLLLALLLRLLLLLRGGRLLRLALRLLLGLLLLGLLLLLLLVAVLAI 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 246 SVLATSLARANRELIQLALHDNLTKLPNRMLLDDRLEQAIQQAIRDDRRFAVLFMDLDGFKAVNDAYGHHLGDLLLIEVA 325
Cdd:COG5001 234 ARLITERKRAEERLRHLAYHDPLTGLPNRRLFLDRLEQALARARRSGRRLALLFIDLDRFKEINDTLGHAAGDELLREVA 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 326 ERIRANVRAQDTIARLGGDEFVLLIE-AREPADAATLAEKLVKRISQPYQISRHEVRISASIGIALYPGDGQTRHELMIN 404
Cdd:COG5001 314 RRLRACLREGDTVARLGGDEFAVLLPdLDDPEDAEAVAERILAALAEPFELDGHELYVSASIGIALYPDDGADAEELLRN 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 405 ADAAMYHAKDQGRNGYCFFESSMNANAQEQLQLLHDLRQALERRQLVLHYQPKVLAPNGPMIGVEALLRWEHPQHGLITP 484
Cdd:COG5001 394 ADLAMYRAKAAGRNRYRFFDPEMDERARERLELEADLRRALERGELELHYQPQVDLATGRIVGAEALLRWQHPERGLVSP 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 485 GQFLPLAEKTGLIVQIGEWVLDEACRQMRLWLDGGHAEWNIAVNLSALQFAHAGLVDSVRNALLRHSLEPSHLILEVTES 564
Cdd:COG5001 474 AEFIPLAEETGLIVPLGEWVLREACRQLAAWQDAGLPDLRVAVNLSARQLRDPDLVDRVRRALAETGLPPSRLELEITES 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 565 TAMRDADASLVILEQLSAMGVGISIDDFGTGYSSLLYLKRLPASELKIDRGFINELAHDSDDAAIVSAIVALGRTLNLKI 644
Cdd:COG5001 554 ALLEDPEEALETLRALRALGVRIALDDFGTGYSSLSYLKRLPVDTLKIDRSFVRDLAEDPDDAAIVRAIIALAHSLGLEV 633
|
650 660 670
....*....|....*....|....*....|....*...
gi 497562044 645 VAEGVETEAQQEFLTRLGCNSLQGFLLGRPMPAEQLLA 682
Cdd:COG5001 634 VAEGVETEEQLEFLRELGCDYAQGYLFSRPLPAEELEA 671
|
|
| PRK10060 |
PRK10060 |
cyclic di-GMP phosphodiesterase; |
254-680 |
5.74e-132 |
|
cyclic di-GMP phosphodiesterase;
Pssm-ID: 236645 [Multi-domain] Cd Length: 663 Bit Score: 404.06 E-value: 5.74e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 254 RANRELIQLALHDNLTKLPNRMLLDDRLEQAIQQaiRDDRRFAVLFMDLDGFKAVNDAYGHHLGDLLLIEVAERIRANVR 333
Cdd:PRK10060 228 RAQERLRILANTDSITGLPNRNAIQELIDHAINA--ADNNQVGIVYLDLDNFKKVNDAYGHMFGDQLLQDVSLAILSCLE 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 334 AQDTIARLGGDEFVLLIEAREPADAATLAEKLVKRISQPYQISRHEVRISASIGIALYPGDGQTRHELMINADAAMYHAK 413
Cdd:PRK10060 306 EDQTLARLGGDEFLVLASHTSQAALEAMASRILTRLRLPFRIGLIEVYTGCSIGIALAPEHGDDSESLIRSADTAMYTAK 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 414 DQGRNGYCFFESSMNANAQEQLQLLHDLRQALERRQLVLHYQPKVLApNGPMIGVEALLRWEHPQHGLITPGQFLPLAEK 493
Cdd:PRK10060 386 EGGRGQFCVFSPEMNQRVFEYLWLDTNLRKALENDQLVIHYQPKITW-RGEVRSLEALVRWQSPERGLIPPLEFISYAEE 464
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 494 TGLIVQIGEWVLDEACRQMRLWLDGGhAEWNIAVNLSALQFAHAGLVDSVRNALLRHSLEPSHLILEVTESTAMRDADAS 573
Cdd:PRK10060 465 SGLIVPLGRWVMLDVVRQVAKWRDKG-INLRVAVNVSARQLADQTIFTALKQALQELNFEYCPIDVELTESCLIENEELA 543
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 574 LVILEQLSAMGVGISIDDFGTGYSSLLYLKRLPASELKIDRGFINELAHDSDDAAIVSAIVALGRTLNLKIVAEGVETEA 653
Cdd:PRK10060 544 LSVIQQFSQLGAQVHLDDFGTGYSSLSQLARFPIDAIKLDQSFVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVETAK 623
|
410 420
....*....|....*....|....*..
gi 497562044 654 QQEFLTRLGCNSLQGFLLGRPMPAEQL 680
Cdd:PRK10060 624 EDAFLTKNGVNERQGFLFAKPMPAVAF 650
|
|
| EAL |
COG2200 |
EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) ... |
140-685 |
5.37e-117 |
|
EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) [Signal transduction mechanisms];
Pssm-ID: 441802 [Multi-domain] Cd Length: 576 Bit Score: 362.57 E-value: 5.37e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 140 LWLGLSILIAVIASGAALWIAFRLRHGSRRIVLVRAGAALVMGCAIVGMHYTGMAAAQFPLGSFCGAAGRGIDNGWLAVL 219
Cdd:COG2200 32 LLLLALASALLLAVAALLAALLAALLLLLALALLLLLLLLLLLLLLLLLLLLALLLLLLLLLLLLLLLLLLLALLLAALL 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 220 VIVITLAVIAIALIVSVLDSRLEARTSVLATSLARANRELIQLALHDNLTKLPNRMLLDDRLEQAIQQAIRDDRRFAVLF 299
Cdd:COG2200 112 ALLLLLLLLLLLLLLSLLLLLVLVLLRLALELLLALLLLALLALLDLLLLLLLRRLLLLLLLLLLLLLLALALLALLLLL 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 300 MDLDGFKAVNDAYGHHLGDLLLIEVAERIRANVRAQDTIARLGGDEFVLLIEAREPADAATLAEKLVKRISQPYQISRHE 379
Cdd:COG2200 192 LLLLLLLLDNDGLGGAGLLLLLLLALLLLLLLARLLLALLGGGGGGFLLLLLLLAAAAAAAAALRLLLLLLLEPLLLGGG 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 380 VRISASIGIALYPGDGQTRHELMINADAAMYHAKDQGRNGYCFFESSMNANAQEQLQLLHDLRQALERRQLVLHYQPKVL 459
Cdd:COG2200 272 LVVVASSGGGAAAPDDGADAALLLAAAAAAAAAAAGGGRGRVVFFAAAEARARRRLALESELREALEEGELRLYYQPIVD 351
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 460 APNGPMIGVEALLRWEHPQHGLITPGQFLPLAEKTGLIVQIGEWVLDEACRQMRLWLDGGHaEWNIAVNLSALQFAHAGL 539
Cdd:COG2200 352 LRTGRVVGYEALLRWRHPDGGLISPAEFIPAAERSGLIVELDRWVLERALRQLARWPERGL-DLRLSVNLSARSLLDPDF 430
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 540 VDSVRNALLRHSLEPSHLILEVTESTAMRDADASLVILEQLSAMGVGISIDDFGTGYSSLLYLKRLPASELKIDRGFINE 619
Cdd:COG2200 431 LERLLELLAEYGLPPERLVLEITESALLEDLEAAIELLARLRALGVRIALDDFGTGYSSLSYLKRLPPDYLKIDRSFVRD 510
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 497562044 620 LAHDSDDAAIVSAIVALGRTLNLKIVAEGVETEAQQEFLTRLGCNSLQGFLLGRPMPAEQLLASVA 685
Cdd:COG2200 511 IARDPRDQAIVRAIVALAHRLGLKVVAEGVETEEQLEALRELGCDYAQGYLFGRPLPLEELEALLR 576
|
|
| EAL |
cd01948 |
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL ... |
439-679 |
2.59e-114 |
|
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.
Pssm-ID: 238923 [Multi-domain] Cd Length: 240 Bit Score: 342.99 E-value: 2.59e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 439 HDLRQALERRQLVLHYQPKVLAPNGPMIGVEALLRWEHPQHGLITPGQFLPLAEKTGLIVQIGEWVLDEACRQMRLWLDG 518
Cdd:cd01948 1 ADLRRALERGEFELYYQPIVDLRTGRIVGYEALLRWRHPEGGLISPAEFIPLAEETGLIVELGRWVLEEACRQLARWQAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 519 GHAeWNIAVNLSALQFAHAGLVDSVRNALLRHSLEPSHLILEVTESTAMRDADASLVILEQLSAMGVGISIDDFGTGYSS 598
Cdd:cd01948 81 GPD-LRLSVNLSARQLRDPDFLDRLLELLAETGLPPRRLVLEITESALIDDLEEALATLRRLRALGVRIALDDFGTGYSS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 599 LLYLKRLPASELKIDRGFINELAHDSDDAAIVSAIVALGRTLNLKIVAEGVETEAQQEFLTRLGCNSLQGFLLGRPMPAE 678
Cdd:cd01948 160 LSYLKRLPVDYLKIDRSFVRDIETDPEDRAIVRAIIALAHSLGLKVVAEGVETEEQLELLRELGCDYVQGYLFSRPLPAE 239
|
.
gi 497562044 679 Q 679
Cdd:cd01948 240 E 240
|
|
| PRK11359 |
PRK11359 |
cyclic-di-GMP phosphodiesterase; Provisional |
256-680 |
3.90e-113 |
|
cyclic-di-GMP phosphodiesterase; Provisional
Pssm-ID: 183097 [Multi-domain] Cd Length: 799 Bit Score: 359.08 E-value: 3.90e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 256 NRELI-QLALHDNLTKLPNRMLLDDRLEQAIQQairdDRRFAVLFMDLDGFKAVNDAYGHHLGDLLLIEVAERIRANVRA 334
Cdd:PRK11359 368 SRQHIeQLIQFDPLTGLPNRNNLHNYLDDLVDK----AVSPVVYLIGVDHFQDVIDSLGYAWADQALLEVVNRFREKLKP 443
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 335 QDTIARLGGDEFVLLIEAREPADAATLAEKLVKRISQPYQISRHEVRISASIGIAlYPGdGQTRHELMINADAAMYHAKD 414
Cdd:PRK11359 444 DQYLCRIEGTQFVLVSLENDVSNITQIADELRNVVSKPIMIDDKPFPLTLSIGIS-YDV-GKNRDYLLSTAHNAMDYIRK 521
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 415 QGRNGYCFFESSMNANAQEQLQLLHDLRQALERRQLVLHYQPKVLAPNGPMIGVEALLRWEHPQHGLITPGQFLPLAEKT 494
Cdd:PRK11359 522 NGGNGWQFFSPAMNEMVKERLVLGAALKEAISNNQLKLVYQPQIFAETGELYGIEALARWHDPLHGHVPPSRFIPLAEEI 601
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 495 GLIVQIGEWVLDEACRQMRLWLDGGHAEWNIAVNLSALQFAHAGLVDSVRNALLRHSLEPSHLILEVTESTAMRDADASL 574
Cdd:PRK11359 602 GEIENIGRWVIAEACRQLAEWRSQNIHIPALSVNLSALHFRSNQLPNQVSDAMQAWGIDGHQLTVEITESMMMEHDTEIF 681
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 575 VILEQLSAMGVGISIDDFGTGYSSLLYLKRLPASELKIDRGFINELAHDSDDAAIVSAIVALGRTLNLKIVAEGVETEAQ 654
Cdd:PRK11359 682 KRIQILRDMGVGLSVDDFGTGFSGLSRLVSLPVTEIKIDKSFVDRCLTEKRILALLEAITSIGQSLNLTVVAEGVETKEQ 761
|
410 420
....*....|....*....|....*.
gi 497562044 655 QEFLTRLGCNSLQGFLLGRPMPAEQL 680
Cdd:PRK11359 762 FEMLRKIHCRVIQGYFFSRPLPAEEI 787
|
|
| EAL |
smart00052 |
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a ... |
439-679 |
1.52e-103 |
|
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a variety of bacteria.
Pssm-ID: 214491 [Multi-domain] Cd Length: 242 Bit Score: 315.70 E-value: 1.52e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 439 HDLRQALERRQLVLHYQPKVLAPNGPMIGVEALLRWEHPQHGLITPGQFLPLAEKTGLIVQIGEWVLDEACRQMRLWLDG 518
Cdd:smart00052 2 RELRQALENGQFLLYYQPIVSLRTGRLVGVEALIRWQHPEGGIISPDEFIPLAEETGLIVPLGRWVLEQACQQLAEWQAQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 519 GHAEWNIAVNLSALQFAHAGLVDSVRNALLRHSLEPSHLILEVTESTAMRDADASLVILEQLSAMGVGISIDDFGTGYSS 598
Cdd:smart00052 82 GPPPLLISINLSARQLISPDLVPRVLELLEETGLPPQRLELEITESVLLDDDESAVATLQRLRELGVRIALDDFGTGYSS 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 599 LLYLKRLPASELKIDRGFINELAHDSDDAAIVSAIVALGRTLNLKIVAEGVETEAQQEFLTRLGCNSLQGFLLGRPMPAE 678
Cdd:smart00052 162 LSYLKRLPVDLLKIDKSFVRDLQTDPEDEAIVQSIIELAQKLGLQVVAEGVETPEQLDLLRSLGCDYGQGYLFSRPLPLD 241
|
.
gi 497562044 679 Q 679
Cdd:smart00052 242 D 242
|
|
| MHYT |
COG3300 |
MHYT domain, NO-binding membrane sensor [Signal transduction mechanisms]; |
1-446 |
4.82e-99 |
|
MHYT domain, NO-binding membrane sensor [Signal transduction mechanisms];
Pssm-ID: 442529 [Multi-domain] Cd Length: 440 Bit Score: 311.12 E-value: 4.82e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 1 MLISSYNQVLVAFSLIVAILASYTALDMAGRVTLAKGREALSWLIGGAFAMGFGIWSMHFVGMLAFSLPIPLGYDLGLTL 80
Cdd:COG3300 2 CLAGSHDPWLVALSVLIAVLGSYTALDLARRARAASGRARRAWLALAALALGGGIWSMHFIAMLAFRLPVPVGYDPPLTL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 81 LSLLLAVGSSAFALWLVCQAELPWQRLALGALLMGSGIAAMHYTGMAALLMMPGIVYDPLWLGLSILIAVIASGAALWIA 160
Cdd:COG3300 82 LSLLVAILASGLALALASRRRLSRLRLLLGGLLMGLGIAAMHYTGMAAMRMAGAISYDPALVALSVLIAVVASTAALWLA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 161 FRLRHGSRRIvlvraGAALVMGCAIVGMHYTGMAAAQFPLGSFCGAAGRGIDNGWLAVLVIVITLAVIAIALIVSVLDSR 240
Cdd:COG3300 162 FRLRSLRRRL-----GAALVMGLAICGMHYTGMAAATFVPDPGAPAPAPGLSPTLLALAVAVVTLLILGLALLASLLDDA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 241 LeaRTSVLATSLARANRELIQLALHDNLTKLPNRMLLDDRLEQAIQQAIRDDRRFAVLFMDLDGFKAVNDAYGHHLGDLL 320
Cdd:COG3300 237 R--RRARAARELASLRLLAALALAGLLLTGLLLALEARGALAALLGAALDELLLDLLLLLDLDGDAALLLALGELLADLL 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 321 LIEVAERIRANVRAQDTIARLGGDEFVLLIEAREPADAATLAEKLVKRISQPYQISRHEVRISASIGIALYPGDGQTRHE 400
Cdd:COG3300 315 LALVAARVVARVRLVARVGGDERDEIVAEDRLRRAEAEAAADAARLALAAAASALSLDALLLLALLAAAALALALAALLA 394
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 497562044 401 LMINADAAMYHAKDQGRNGYCFFESSMNANAQEQLQLLHDLRQALE 446
Cdd:COG3300 395 LRALAAADALTVEADASSAAAELLLAAALLLLLLLLLLLLLLLARD 440
|
|
| PRK13561 |
PRK13561 |
putative diguanylate cyclase; Provisional |
251-679 |
1.55e-95 |
|
putative diguanylate cyclase; Provisional
Pssm-ID: 184143 [Multi-domain] Cd Length: 651 Bit Score: 308.57 E-value: 1.55e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 251 SLARANRELIQLALHDNLTKLPNRMLLDDRLEQAIqqaiRDDRRFAVLFMDLDGFKAVNDAYGHHLGDLLLIEVAERIRA 330
Cdd:PRK13561 219 LLQRQYEEQSRNATRFPVSDLPNKALLMALLEQVV----ARKQTTALMIITCETLRDTAGVLKEAQREILLLTLVEKLKS 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 331 NVRAQDTIARLGGDEFVLLIE-AREPADAATLAEKLVKRISQPYQISRHEVRISASIGIALYPGDgQTRHELMINADAAM 409
Cdd:PRK13561 295 VLSPRMVLAQISGYDFAIIANgVKEPWHAITLGQQVLTIINERLPIQRIQLRPSCSIGIAMFYGD-LTAEQLYSRAISAA 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 410 YHAKDQGRNGYCFFESSMNANAQEQLQLLHDLRQALERRQLVLHYQPKVLAPNGPMIGVEALLRWEHPQHGLITPGQFLP 489
Cdd:PRK13561 374 FTARRKGKNQIQFFDPQQMEAAQKRLTEESDILNALENHQFAIWLQPQVEMRSGKLVSAEALLRMQQPDGSWDLPEGLID 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 490 LAEKTGLIVQIGEWVLDEACRQMRLWLDGGhAEWNIAVNLSALQFAHAGLVDSVRNALLRHSLEPSHLILEVTESTAMRD 569
Cdd:PRK13561 454 RIESCGLMVTVGHWVLEESCRLLAAWQERG-IMLPLSVNLSALQLMHPNMVADMLELLTRYRIQPGTLILEVTESRRIDD 532
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 570 ADASLVILEQLSAMGVGISIDDFGTGYSSLLYL---KRLPASELKIDRGFINELahdSDDAAIVSAIVALGRTLNLKIVA 646
Cdd:PRK13561 533 PHAAVAILRPLRNAGVRVALDDFGMGYAGLRQLqhmKSLPIDVLKIDKMFVDGL---PEDDSMVAAIIMLAQSLNLQVIA 609
|
410 420 430
....*....|....*....|....*....|...
gi 497562044 647 EGVETEAQQEFLTRLGCNSLQGFLLGRPMPAEQ 679
Cdd:PRK13561 610 EGVETEAQRDWLLKAGVGIAQGFLFARALPIEI 642
|
|
| YjcC |
COG4943 |
Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal ... |
432-685 |
5.27e-79 |
|
Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal transduction mechanisms];
Pssm-ID: 443970 [Multi-domain] Cd Length: 528 Bit Score: 261.39 E-value: 5.27e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 432 QEQLQLLHDLRQALERRQLVLHYQPKVLAPNGPMIGVEALLRWEHPQHGLITPGQFLPLAEKTGLIVQIGEWVLDEACRQ 511
Cdd:COG4943 267 RRRLSPRRRLRRAIKRREFYVHYQPIVDLKTGRCVGAEALVRWRDPDGSVISPDIFIPLAEQSGLISPLTRQVIEQVFRD 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 512 MRLWLdGGHAEWNIAVNLSALQFAHAGLVDSVRNALLRHSLEPSHLILEVTESTAMRDADASLVIlEQLSAMGVGISIDD 591
Cdd:COG4943 347 LGDLL-AADPDFHISINLSASDLLSPRFLDDLERLLARTGVAPQQIVLEITERGFIDPAKARAVI-AALREAGHRIAIDD 424
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 592 FGTGYSSLLYLKRLPASELKIDRGFINELAHDSDDAAIVSAIVALGRTLNLKIVAEGVETEAQQEFLTRLGCNSLQGFLL 671
Cdd:COG4943 425 FGTGYSSLSYLQTLPVDILKIDKSFVDAIGTDSANSAVVPHIIEMAKTLNLDVVAEGVETEEQADYLRARGVQYGQGWLF 504
|
250
....*....|....
gi 497562044 672 GRPMPAEQLLASVA 685
Cdd:COG4943 505 AKPLPAEEFIAWLA 518
|
|
| T2SS_HK |
NF038348 |
histidine kinase; |
5-259 |
1.77e-78 |
|
histidine kinase;
Pssm-ID: 439642 [Multi-domain] Cd Length: 574 Bit Score: 261.42 E-value: 1.77e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 5 SYNQVLVAFSLIVAILASYTALDMAGRVTLA-KGREALSWLIGGAFAMGFGIWSMHFVGMLAFSLPIPLGYDLGLTLLSL 83
Cdd:NF038348 4 TYDLSLVLLSLVIATLASYTALDLSALISLLdKPRLRRAWLAGGAAAMGTGIWAMHFVGMLAFSLPIPLGYDLRETGLSL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 84 LLAVGSSAFALWLVCQAELPWQRLALGALLMGSGIAAMHYTGMAALLMMPGIVYDPLWLGLSILIAVIASGAALWIAFRL 163
Cdd:NF038348 84 AIAMVVSYFALNAVTRAKLTRERLAAGGVLMGLGIAGMHYTGMAALQMQPGIRYDSALFVASIGIAILASTAALWLAHRL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 164 R-HGSRRIVLVRAGAALVMGCAIVGMHYTGMAAAQFPLGSFCGAAgRGIDNGWLAVLVIVITLAVIAIALIVSVLDSR-- 240
Cdd:NF038348 164 RtENAGRVIVKRIGAATVMGVAITGMHYTGMAAAHFAPNARCGAA-NGISGPWLGTTIALFTATILIVTLVISRFDARtm 242
|
250 260
....*....|....*....|
gi 497562044 241 -LEARTSVLATSLARANREL 259
Cdd:NF038348 243 fLRGITDALEDLVQLRTAEL 262
|
|
| EAL |
pfam00563 |
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL ... |
440-674 |
1.83e-78 |
|
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.
Pssm-ID: 425752 [Multi-domain] Cd Length: 235 Bit Score: 249.93 E-value: 1.83e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 440 DLRQALERRQLVLHYQPKVLAPNGPMIGVEALLRWEHPQHGLITPGQFLPLAEKTGLIVQIGEWVLDEACRQMRLWLDGG 519
Cdd:pfam00563 3 ALRRALENGEFVLYYQPIVDLRTGRVVGYEALLRWQHPDGGLISPARFLPLAEELGLIAELDRWVLEQALADLAQLQLGP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 520 HAewNIAVNLSALQFAHAGLVDSVRNALLRHSLEPSHLILEVTESTAMRDADASLVILEQLSAMGVGISIDDFGTGYSSL 599
Cdd:pfam00563 83 DI--KLSINLSPASLADPGFLELLRALLKQAGPPPSRLVLEITESDLLARLEALREVLKRLRALGIRIALDDFGTGYSSL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497562044 600 LYLKRLPASELKIDRGFINELAHDSDDAAIVSAIVALGRTLNLKIVAEGVETEAQQEFLTRLGCNSLQGFLLGRP 674
Cdd:pfam00563 161 SYLLRLPPDFVKIDRSLIADIDKDGEARAIVRALIALAHSLGIKVVAEGVETEEQLEALRELGCDLVQGYYFSKP 235
|
|
| PRK11829 |
PRK11829 |
biofilm formation regulator HmsP; Provisional |
252-682 |
7.77e-77 |
|
biofilm formation regulator HmsP; Provisional
Pssm-ID: 183329 [Multi-domain] Cd Length: 660 Bit Score: 259.10 E-value: 7.77e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 252 LARANRELIQLALHDNLTKLPNRMLLDDRLEQAIQQAIRDDRrFAVLFMDLDGFKAVNDAYGHHLGDLLLIEVAERIRAN 331
Cdd:PRK11829 221 LADAYADMGRISHRFPVTELPNRSLFISLLEKEIASSTRTDH-FHLLVIGIETLQEVSGAMSEAQHQQLLLTIVQRIEQC 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 332 VRAQDTIARLGGDEFVLLI-EAREPADAATLAEKLVKRISQPYQISRHEVRISASIGIALYPGDGQTRHELMINADAAMY 410
Cdd:PRK11829 300 IDDSDLLAQLSKTEFAVLArGTRRSFPAMQLARRIMSQVTQPLFFDEITLRPSASIGITRYQAQQDTAESMMRNASTAMM 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 411 HAKDQGRNGYCFFESSMNANAQEQLQLLHDLRQALERRQLVLHYQPKVLAPNGPMIGVEALLRWEHPQHGLITPGQFLPL 490
Cdd:PRK11829 380 AAHHEGRNQIMVFEPHLIEKTHKRLTQENDLLQAIENHDFTLFLQPQWDMKRQQVIGAEALLRWCQPDGSYVLPSGFVHF 459
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 491 AEKTGLIVQIGEWVLDEACRQMRLWLDGGhAEWNIAVNLSALQFAHAGLVDSVRNALLRHSLEPSHLILEVTESTAMRDA 570
Cdd:PRK11829 460 AEEEGMMVPLGNWVLEEACRILADWKARG-VSLPLSVNISGLQVQNKQFLPHLKTLISHYHIDPQQLLLEITETAQIQDL 538
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 571 DASLVILEQLSAMGVGISIDDFGTGYSSLLYL---KRLPASELKIDRGFINELAHDSDDAAIVSAIvalGRTLNLKIVAE 647
Cdd:PRK11829 539 DEALRLLRELQGLGLLIALDDFGIGYSSLRYLnhlKSLPIHMIKLDKSFVKNLPEDDAIARIISCV---SDVLKVRVMAE 615
|
410 420 430
....*....|....*....|....*....|....*
gi 497562044 648 GVETEAQQEFLTRLGCNSLQGFLLGRPMPAEQLLA 682
Cdd:PRK11829 616 GVETEEQRQWLLEHGIQCGQGFLFSPPLPRAEFEA 650
|
|
| GGDEF |
cd01949 |
Diguanylate-cyclase (DGC) or GGDEF domain; Diguanylate-cyclase (DGC) or GGDEF domain: ... |
264-421 |
2.00e-69 |
|
Diguanylate-cyclase (DGC) or GGDEF domain; Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.
Pssm-ID: 143635 [Multi-domain] Cd Length: 158 Bit Score: 223.20 E-value: 2.00e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 264 LHDNLTKLPNRMLLDDRLEQAIQQAIRDDRRFAVLFMDLDGFKAVNDAYGHHLGDLLLIEVAERIRANVRAQDTIARLGG 343
Cdd:cd01949 1 YTDPLTGLPNRRAFEERLERLLARARRSGRPLALLLIDIDHFKQINDTYGHAAGDEVLKEVAERLRSSLRESDLVARLGG 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 497562044 344 DEFVLLIEAREPADAATLAEKLVKRISQPYQISRHEVRISASIGIALYPGDGQTRHELMINADAAMYHAKDQGRNGYC 421
Cdd:cd01949 81 DEFAILLPGTDLEEAEALAERLREAIEEPFFIDGQEIRVTASIGIATYPEDGEDAEELLRRADEALYRAKRSGRNRVV 158
|
|
| GGDEF |
COG2199 |
GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants ... |
150-423 |
6.04e-68 |
|
GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants [Signal transduction mechanisms];
Pssm-ID: 441801 [Multi-domain] Cd Length: 275 Bit Score: 224.09 E-value: 6.04e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 150 VIASGAALWIAFRLRHGSRRIVLVRAGAALVMGCAIVGMHYTGMAAAQFPLGSFCGAAGRGIDNGWLAVLVIVITLAVIA 229
Cdd:COG2199 1 VLLLLLLLLALLLLLLLLLLSLLLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLVLLLLALGLLLLALLLLSLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 230 IALIVSVLDSRLEARTSVLATSLARANRELIQLALHDNLTKLPNRMLLDDRLEQAIQQAIRDDRRFAVLFMDLDGFKAVN 309
Cdd:COG2199 81 LELLLLLLALLLLLLALEDITELRRLEERLRRLATHDPLTGLPNRRAFEERLERELARARREGRPLALLLIDLDHFKRIN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 310 DAYGHHLGDLLLIEVAERIRANVRAQDTIARLGGDEFVLLIEAREPADAATLAEKLVKRISQ-PYQISRHEVRISASIGI 388
Cdd:COG2199 161 DTYGHAAGDEVLKEVARRLRASLRESDLVARLGGDEFAVLLPGTDLEEAEALAERLREALEQlPFELEGKELRVTVSIGV 240
|
250 260 270
....*....|....*....|....*....|....*
gi 497562044 389 ALYPGDGQTRHELMINADAAMYHAKDQGRNGYCFF 423
Cdd:COG2199 241 ALYPEDGDSAEELLRRADLALYRAKRAGRNRVVVY 275
|
|
| PRK09776 |
PRK09776 |
putative diguanylate cyclase; Provisional |
253-683 |
3.55e-64 |
|
putative diguanylate cyclase; Provisional
Pssm-ID: 182070 [Multi-domain] Cd Length: 1092 Bit Score: 230.71 E-value: 3.55e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 253 ARA-NRELIQLALHDNLTKLPNRMLLDDRLEQAIQQAIRDDRRFAVLFMDLDGFKAVNDAYGHHLGDLLLIEVAERIRAN 331
Cdd:PRK09776 654 SRKmLRQLSYSASHDALTHLANRASFEKQLRRLLQTVNSTHQRHALVFIDLDRFKAVNDSAGHAAGDALLRELASLMLSM 733
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 332 VRAQDTIARLGGDEFVLLIEAREPADAATLAEKLVKRI-SQPYQISRHEVRISASIGIALYPGDGQTRHELMINADAAMY 410
Cdd:PRK09776 734 LRSSDVLARLGGDEFGLLLPDCNVESARFIATRIISAInDYHFPWEGRVYRVGASAGITLIDANNHQASEVMSQADIACY 813
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 411 HAKDQGRNGYCFFESSMNA--NAQEQLQLLHDLRQALERRQLVLHYQpkVLAPNGPMIG--VEALLRWEHPQHGLITPGQ 486
Cdd:PRK09776 814 AAKNAGRGRVTVYEPQQAAahSEHRALSLAEQWRMIKENQLMMLAHG--VASPRIPEARnhWLISLRLWDPEGEIIDEGA 891
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 487 FLPLAEKTGLIVQIGEWVLDEACRQM--RLWLDGghaeWNIAVNLSALQFAHAGLVDSVRNALLRHSLEPSHLILEVTES 564
Cdd:PRK09776 892 FRPAAEDPALMHALDRRVIHEFFRQAakAVASKG----LSIALPLSVAGLSSPTLLPFLLEQLENSPLPPRLLHLEITET 967
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 565 TAMRDADASLVILEQLSAMGVGISIDDFGTGYSSLLYLKRLPASELKIDRGFINELAHDSDDAAIVSAIVALGRTLNLKI 644
Cdd:PRK09776 968 ALLNHAESASRLVQKLRLAGCRVVLSDFGRGLSSFNYLKAFMADYLKLDGELVANLHGNLMDEMLISIIQGHAQRLGMKT 1047
|
410 420 430
....*....|....*....|....*....|....*....
gi 497562044 645 VAEGVETEAQQEFLTRLGCNSLQGFLLGRPMPAEQLLAS 683
Cdd:PRK09776 1048 IAGPVELPLVLDTLSGIGVDLAYGYAIARPQPLDLLLNS 1086
|
|
| GGDEF |
pfam00990 |
Diguanylate cyclase, GGDEF domain; This domain is found linked to a wide range of ... |
263-418 |
1.97e-58 |
|
Diguanylate cyclase, GGDEF domain; This domain is found linked to a wide range of non-homologous domains in a variety of bacteria. It has been shown to be homologous to the adenylyl cyclase catalytic domain and has diguanylate cyclase activity. This observation correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. In the WspR protein of Pseudomonas aeruginosa, the GGDEF domain acts as a diguanylate cyclase, PDB:3bre, when the whole molecule appears to form a tetramer consisting of two symmetrically-related dimers representing a biological unit. The active site is the GGD/EF motif, buried in the structure, and the cyclic dimeric guanosine monophosphate (c-di-GMP) bind to the inhibitory-motif RxxD on the surface. The enzyme thus catalyzes the cyclization of two guanosine triphosphate (GTP) molecules to one c-di-GMP molecule.
Pssm-ID: 425976 [Multi-domain] Cd Length: 160 Bit Score: 194.39 E-value: 1.97e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 263 ALHDNLTKLPNRMLLDDRLEQAIQQAIRDDRRFAVLFMDLDGFKAVNDAYGHHLGDLLLIEVAERIRANVRAQDTIARLG 342
Cdd:pfam00990 1 AAHDPLTGLPNRRYFEEQLEQELQRALREGSPVAVLLIDLDNFKRINDTYGHSVGDEVLQEVAQRLSSSLRRSDLVARLG 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497562044 343 GDEFVLLIEAREPADAATLAE---KLVKRISQPYQISRHEVRISASIGIALYPGDGQTRHELMINADAAMYHAKDQGRN 418
Cdd:pfam00990 81 GDEFAILLPETSLEGAQELAErirRLLAKLKIPHTVSGLPLYVTISIGIAAYPNDGEDPEDLLKRADTALYQAKQAGRN 159
|
|
| GGDEF |
smart00267 |
diguanylate cyclase; Diguanylate cyclase, present in a variety of bacteria. |
261-423 |
4.27e-58 |
|
diguanylate cyclase; Diguanylate cyclase, present in a variety of bacteria.
Pssm-ID: 128563 [Multi-domain] Cd Length: 163 Bit Score: 193.62 E-value: 4.27e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 261 QLALHDNLTKLPNRMLLDDRLEQAIQQAIRDDRRFAVLFMDLDGFKAVNDAYGHHLGDLLLIEVAERIRANVRAQDTIAR 340
Cdd:smart00267 1 RLAFRDPLTGLPNRRYFEEELEQELQRAQRQGSPFALLLIDLDNFKDINDTYGHAVGDELLQEVAQRLSSCLRPGDLLAR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 341 LGGDEFVLLIEAREPADAATLAEKLVKRISQPYQISRHEVRISASIGIALYPGDGQTRHELMINADAAMYHAKDQGRNGY 420
Cdd:smart00267 81 LGGDEFALLLPETSLEEAIALAERILQQLREPIIIHGIPLYLTISIGVAAYPNPGEDAEDLLKRADTALYQAKKAGRNQV 160
|
...
gi 497562044 421 CFF 423
Cdd:smart00267 161 AVY 163
|
|
| PRK10551 |
PRK10551 |
cyclic di-GMP phosphodiesterase; |
443-682 |
5.20e-46 |
|
cyclic di-GMP phosphodiesterase;
Pssm-ID: 182541 [Multi-domain] Cd Length: 518 Bit Score: 171.33 E-value: 5.20e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 443 QALERRQLVLHYQPKVLAPNGPMIGVEALLRWEHPQHGLITPGQFLPLAEKTGLIVQIGEWVLDEACR---QMRLWLDGG 519
Cdd:PRK10551 270 TGIKRGQFYVEYQPVVDTQTLRVTGLEALLRWRHPTAGEIPPDAFINYAEAQKLIVPLTQHLFELIARdaaELQKVLPVG 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 520 HaewNIAVNLSALQFAHAGLVDSVRNalLRHSLEPSH--LILEVTESTAMRDADAsLVILEQLSAMGVGISIDDFGTGYS 597
Cdd:PRK10551 350 A---KLGINISPAHLHSDSFKADVQR--LLASLPADHfqIVLEITERDMVQEEEA-TKLFAWLHSQGIEIAIDDFGTGHS 423
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 598 SLLYLKRLPASELKIDRGFINELAHDSDDAAIVSAIVALGRTLNLKIVAEGVETEAQQEFLTRLGCNSLQGFLLGRPMPA 677
Cdd:PRK10551 424 ALIYLERFTLDYLKIDRGFIQAIGTETVTSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLRERGVNFLQGYWISRPLPL 503
|
....*
gi 497562044 678 EQLLA 682
Cdd:PRK10551 504 EDFVR 508
|
|
| GGDEF |
TIGR00254 |
diguanylate cyclase (GGDEF) domain; The GGDEF domain is named for the motif GG[DE]EF shared by ... |
262-420 |
1.39e-44 |
|
diguanylate cyclase (GGDEF) domain; The GGDEF domain is named for the motif GG[DE]EF shared by many proteins carrying the domain. There is evidence that the domain has diguanylate cyclase activity. Several proteins carrying this domain also carry domains with functions relating to environmental sensing. These include PleD, a response regulator protein involved in the swarmer-to-stalked cell transition in Caulobacter crescentus, and FixL, a heme-containing oxygen sensor protein. [Regulatory functions, Small molecule interactions, Signal transduction, Other]
Pssm-ID: 272984 [Multi-domain] Cd Length: 165 Bit Score: 157.11 E-value: 1.39e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 262 LALHDNLTKLPNRMLLDDRLEQAIQQAIRDDRRFAVLFMDLDGFKAVNDAYGHHLGDLLLIEVAERIRANVRAQDTIARL 341
Cdd:TIGR00254 1 QAVRDPLTGLYNRRYLEEMLDSELKRARRFQRSFSVLMIDIDNFKKINDTLGHDVGDEVLREVARILQSSVRGSDVVGRY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 342 GGDEFVLLIEAREPADAATLAEKLVKRISQ-PYQISRHE-VRISASIGIALYPGDGQTRHELMINADAAMYHAKDQGRNG 419
Cdd:TIGR00254 81 GGEEFVVILPGTPLEDALSKAERLRDAINSkPIEVAGSEtLTVTVSIGVACYPGHGLTLEELLKRADEALYQAKKAGRNR 160
|
.
gi 497562044 420 Y 420
Cdd:TIGR00254 161 V 161
|
|
| pleD |
PRK09581 |
response regulator PleD; Reviewed |
260-418 |
6.77e-36 |
|
response regulator PleD; Reviewed
Pssm-ID: 236577 [Multi-domain] Cd Length: 457 Bit Score: 141.19 E-value: 6.77e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 260 IQLALHDNLTKLPNRMLLDDRLEQAIQQAIRDDRRFAVLFMDLDGFKAVNDAYGHHLGDLLLIEVAERIRANVRAQDTIA 339
Cdd:PRK09581 289 IEMAVTDGLTGLHNRRYFDMHLKNLIERANERGKPLSLMMIDIDHFKKVNDTYGHDAGDEVLREFAKRLRNNIRGTDLIA 368
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 340 RLGGDEFVLLIEAREPADAATLAEKLVKRISQ-PYQISRHEVRIS--ASIGIALYPGDGQTRHELMINADAAMYHAKDQG 416
Cdd:PRK09581 369 RYGGEEFVVVMPDTDIEDAIAVAERIRRKIAEePFIISDGKERLNvtVSIGVAELRPSGDTIEALIKRADKALYEAKNTG 448
|
..
gi 497562044 417 RN 418
Cdd:PRK09581 449 RN 450
|
|
| PRK09894 |
PRK09894 |
diguanylate cyclase; Provisional |
238-418 |
5.45e-31 |
|
diguanylate cyclase; Provisional
Pssm-ID: 182133 [Multi-domain] Cd Length: 296 Bit Score: 123.25 E-value: 5.45e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 238 DSRLEARTSvlatSLARANRELIQLALH-DNLTKLPNRMLLDDRLEQaiQQAIRDDRRFAVLFMDLDGFKAVNDAYGHHL 316
Cdd:PRK09894 107 QEGLLSFTA----ALTDYKIYLLTIRSNmDVLTGLPGRRVLDESFDH--QLRNREPQNLYLALLDIDRFKLVNDTYGHLI 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 317 GDLLLIEVAERIRANVRAQDTIARLGGDEFVLLIEAREPADAATLAEKLVKRIS-QPYQISRHEVRISASIGIA-LYPgd 394
Cdd:PRK09894 181 GDVVLRTLATYLASWTRDYETVYRYGGEEFIICLKAATDEEACRAGERIRQLIAnHAITHSDGRINITATFGVSrAFP-- 258
|
170 180
....*....|....*....|....
gi 497562044 395 GQTRHELMINADAAMYHAKDQGRN 418
Cdd:PRK09894 259 EETLDVVIGRADRAMYEGKQTGRN 282
|
|
| PRK15426 |
PRK15426 |
cellulose biosynthesis regulator YedQ; |
257-434 |
2.44e-30 |
|
cellulose biosynthesis regulator YedQ;
Pssm-ID: 237964 [Multi-domain] Cd Length: 570 Bit Score: 126.28 E-value: 2.44e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 257 RELIQLALHDNLTKLPNRMLLDDRLEQAIQQAIRDDRRFAVLFMDLDGFKAVNDAYGHHLGDLLLIEVAERIRANVRAQD 336
Cdd:PRK15426 392 SSLQWQAWHDPLTRLYNRGALFEKARALAKRCQRDQQPFSVIQLDLDHFKSINDRFGHQAGDRVLSHAAGLISSSLRAQD 471
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 337 TIARLGGDEFVLLIEAREPADAATLAEKLVKRISQPYQISRHEV--RISASIGI--ALYPGDGQTRHELMInADAAMYHA 412
Cdd:PRK15426 472 VAGRVGGEEFCVVLPGASLAEAAQVAERIRLRINEKEILVAKSTtiRISASLGVssAEEDGDYDFEQLQSL-ADRRLYLA 550
|
170 180
....*....|....*....|..
gi 497562044 413 KDQGRNGYCFFEssmNANAQEQ 434
Cdd:PRK15426 551 KQAGRNRVCASD---NAHEREV 569
|
|
| PRK11059 |
PRK11059 |
regulatory protein CsrD; Provisional |
214-677 |
8.43e-24 |
|
regulatory protein CsrD; Provisional
Pssm-ID: 236833 [Multi-domain] Cd Length: 640 Bit Score: 106.49 E-value: 8.43e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 214 GWLAVLVIVITLAVIAIALIVSV------LD--SRLEAR---------TSVLATSL----ARANRELIQL---------- 262
Cdd:PRK11059 137 SLYATASLTLAIGFIVLMLFLGVrwlrrqLAgqELLEERarrilngerEQAVAGSGyewpRTASRALDHLlselqdaree 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 263 -----------ALHDNLTKLPNRMLLDDRLEQAIQQAIRDDRRFAVLFMDLDGFKAVNDAYGHHLGDLLLIEVAERIRAN 331
Cdd:PRK11059 217 rsrfdtfirsnAFQDAKTGLGNRLFFDNQLATLLEDQEMVGAHGVVMLIRLPDFDLLQEEWGESQVEELLFELINLLSTF 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 332 V-RAQDTI-ARLGGDEFVLLIEAREPADAATLAEKLVK---RISQPYQISR----HevrisasIGIALYPGdGQTRHELM 402
Cdd:PRK11059 297 VmRYPGALlARYSRSDFAVLLPHRSLKEADSLASQLLKavdALPPPKMLDRddflH-------IGICAYRS-GQSTEQVM 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 403 INADAAMYHAKDQGRNGYCFFEssmNANAQEQ---------LqllhdLRQALERRQLVLHYQPKVLApNGPMIGVEALLR 473
Cdd:PRK11059 369 EEAEMALRSAQLQGGNGWFVYD---KAQLPEKgrgsvrwrtL-----LEQTLVRGGPRLYQQPAVTR-DGKVHHRELFCR 439
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 474 WEHPQHGLITPGQFLPLAEKTGLIVQIGEWVLDEACRQMRLWldgghAEWNIAVNLSALQFAHAGLVDSVRNALLRHS-L 552
Cdd:PRK11059 440 IRDGQGELLSAELFMPMVQQLGLSEQYDRQVIERVLPLLRYW-----PEENLSINLSVDSLLSRAFQRWLRDTLLQCPrS 514
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 553 EPSHLILEVTESTAMRDADASLVILEQLSAMGVGISIDDFGTGYSSLLYLKRLPASELKIDRGFINELAHDSDDAAIV-S 631
Cdd:PRK11059 515 QRKRLIFELAEADVCQHISRLRPVLRMLRGLGCRLAVDQAGLTVVSTSYIKELNVELIKLHPSLVRNIHKRTENQLFVrS 594
|
490 500 510 520
....*....|....*....|....*....|....*....|....*.
gi 497562044 632 AIVALGRTlNLKIVAEGVETEAQQEFLTRLGCNSLQGFLLGRPMPA 677
Cdd:PRK11059 595 LVGACAGT-ETQVFATGVESREEWQTLQELGVSGGQGDFFAESQPL 639
|
|
| diguan_DgcJ |
NF040885 |
diguanylate cyclase DgcJ; |
266-417 |
6.58e-22 |
|
diguanylate cyclase DgcJ;
Pssm-ID: 468821 [Multi-domain] Cd Length: 490 Bit Score: 99.65 E-value: 6.58e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 266 DNLTKLPNRMLLDDRLEQAIQQAIRddRRFAVLFM--DLDGFKAVNDAYGHHLGDLLLIEVAERIRANVRAQDTIARLGG 343
Cdd:NF040885 344 DSMTGLYNRKILTPTLEQRLQRLTE--KGIPVTFIalDCDKLKHINDTLGHHEGDRAITLLAQAISASIRKSDYGIRLGG 421
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 497562044 344 DEF-VLLIEArEPADAAtlaeKLVKRISQPYQISRHEVRISASIGI-ALYPGDgqTRHELMINADAAMYHAKDQGR 417
Cdd:NF040885 422 DEFcIILIDY-EEAEAQ----NLIERIRQHLRTIDPDKRVSFSWGAyQMQPGD--TLDDAYKAADERLYLNKKQKH 490
|
|
| adrA |
PRK10245 |
diguanylate cyclase AdrA; Provisional |
140-418 |
2.27e-20 |
|
diguanylate cyclase AdrA; Provisional
Pssm-ID: 182329 [Multi-domain] Cd Length: 366 Bit Score: 93.35 E-value: 2.27e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 140 LWLGLsILIAVIASGAALWIAFRLRHGSRRIVLVRAGAALVMGCAIVGMHYTGMAAAqFPLGSFcgaagrgidNGWLAVL 219
Cdd:PRK10245 106 MWVGV-MGVNVLPSTAMLMIMCLNLMGAGGPRLFVAGLVLMVVSCLVTLELTGITVS-FNSAPL---------EWWLSLP 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 220 VIVItlaviaialiVSVLDSRLEARTsvlATSLARANRELIQLALHDNLTKLPNRMLLDDRLEQAIQQAIRDDRRFAVLF 299
Cdd:PRK10245 175 VIVI----------YPLLFAWVSYQT---ATKLAEHKRRLQVMSTRDGMTGVYNRRHWETLLRNEFDNCRRHHRDATLLI 241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 300 MDLDGFKAVNDAYGHHLGDLLLIEVAERIRANVRAQDTIARLGGDEFVlLIEAREPADAATLAEKLV-KRISQPYQISRH 378
Cdd:PRK10245 242 IDIDHFKSINDTWGHDVGDEAIVALTRQLQITLRGSDVIGRFGGDEFA-VIMSGTPAESAITAMSRVhEGLNTLRLPNAP 320
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 497562044 379 EVRISASIGIA-LYPGDGQTRhELMINADAAMYHAKDQGRN 418
Cdd:PRK10245 321 QVTLRISVGVApLNPQMSHYR-EWLKSADLALYKAKNAGRN 360
|
|
| PRK09966 |
PRK09966 |
diguanylate cyclase DgcN; |
252-415 |
4.22e-17 |
|
diguanylate cyclase DgcN;
Pssm-ID: 182171 [Multi-domain] Cd Length: 407 Bit Score: 83.90 E-value: 4.22e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 252 LARANRELIQLALHDNLTKLPNRMllddRLEQAIQQAIRDD---RRFAVLFMDLDGFKAVNDAYGHHLGDLLLIEVAERI 328
Cdd:PRK09966 237 LQAKNAQLLRTALHDPLTGLANRA----AFRSGINTLMNNSdarKTSALLFLDGDNFKYINDTWGHATGDRVLIEIAKRL 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 329 RANVRAQDTIARLGGDEFVL-LIEAREPADAATLAEKLVKRISQPYQISR-HEVRISASIGIALyPGDGQTRHELMINAD 406
Cdd:PRK09966 313 AEFGGLRHKAYRLGGDEFAMvLYDVQSESEVQQICSALTQIFNLPFDLHNgHQTTMTLSIGYAM-TIEHASAEKLQELAD 391
|
....*....
gi 497562044 407 AAMYHAKDQ 415
Cdd:PRK09966 392 HNMYQAKHQ 400
|
|
| Nucleotidyl_cyc_III |
cd07556 |
Class III nucleotidyl cyclases; Class III nucleotidyl cyclases are the largest, most diverse ... |
297-389 |
3.60e-14 |
|
Class III nucleotidyl cyclases; Class III nucleotidyl cyclases are the largest, most diverse group of nucleotidyl cyclases (NC's) containing prokaryotic and eukaryotic proteins. They can be divided into two major groups; the mononucleotidyl cyclases (MNC's) and the diguanylate cyclases (DGC's). The MNC's, which include the adenylate cyclases (AC's) and the guanylate cyclases (GC's), have a conserved cyclase homology domain (CHD), while the DGC's have a conserved GGDEF domain, named after a conserved motif within this subgroup. Their products, cyclic guanylyl and adenylyl nucleotides, are second messengers that play important roles in eukaryotic signal transduction and prokaryotic sensory pathways.
Pssm-ID: 143637 [Multi-domain] Cd Length: 133 Bit Score: 69.69 E-value: 3.60e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 297 VLFMDLDGFKAVNDAYGHHLGDLLLIEVAERIRANV-RAQDTIARLGGDEFVLLIEAREPADAATLAEKLVKRISQPYQI 375
Cdd:cd07556 4 ILFADIVGFTSLADALGPDEGDELLNELAGRFDSLIrRSGDLKIKTIGDEFMVVSGLDHPAAAVAFAEDMREAVSALNQS 83
|
90
....*....|....
gi 497562044 376 SRHEVRIsaSIGIA 389
Cdd:cd07556 84 EGNPVRV--RIGIH 95
|
|
| MHYT |
pfam03707 |
Bacterial signalling protein N terminal repeat; Found as an N terminal triplet tandem repeat ... |
116-169 |
1.21e-13 |
|
Bacterial signalling protein N terminal repeat; Found as an N terminal triplet tandem repeat in bacterial signalling proteins. Family includes CoxC and CoxH from P.carboxydovorans. Each repeat contains two transmembrane helices. Domain is also described as the MHYT domain.
Pssm-ID: 427453 [Multi-domain] Cd Length: 54 Bit Score: 65.69 E-value: 1.21e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 497562044 116 SGIAAMHYTGMAALLMMPGIVYDPLWLGLSILIAVIASGAALWIAFRLRHGSRR 169
Cdd:pfam03707 1 LGIWSMHFIGMLAFRLPGPIGYDPALTALSLVIAVVASGAALWLAFRRRDTRLR 54
|
|
| MHYT |
pfam03707 |
Bacterial signalling protein N terminal repeat; Found as an N terminal triplet tandem repeat ... |
53-106 |
1.60e-10 |
|
Bacterial signalling protein N terminal repeat; Found as an N terminal triplet tandem repeat in bacterial signalling proteins. Family includes CoxC and CoxH from P.carboxydovorans. Each repeat contains two transmembrane helices. Domain is also described as the MHYT domain.
Pssm-ID: 427453 [Multi-domain] Cd Length: 54 Bit Score: 56.84 E-value: 1.60e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 497562044 53 FGIWSMHFVGMLAFSLPIPLGYDLGLTLLSLLLAVGSSAFALWLVCQAELPWQR 106
Cdd:pfam03707 1 LGIWSMHFIGMLAFRLPGPIGYDPALTALSLVIAVVASGAALWLAFRRRDTRLR 54
|
|
| PleD |
COG3706 |
Two-component response regulator, PleD family, consists of two REC domains and a diguanylate ... |
336-413 |
1.50e-08 |
|
Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain [Signal transduction mechanisms, Transcription];
Pssm-ID: 442920 [Multi-domain] Cd Length: 179 Bit Score: 54.91 E-value: 1.50e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 497562044 336 DTIARLGGDEFVLLIEAREPADAATLAEKLVKRISQPyqisrHEVRISASIGIAlypgdgqtRHELMINADaAMYHAK 413
Cdd:COG3706 116 DLVARYGGEEFAILLPGTDLEGALAVAERIREAVAEL-----PSLRVTVSIGVA--------GDSLLKRAD-ALYQAR 179
|
|
| MHYT |
pfam03707 |
Bacterial signalling protein N terminal repeat; Found as an N terminal triplet tandem repeat ... |
183-241 |
6.80e-07 |
|
Bacterial signalling protein N terminal repeat; Found as an N terminal triplet tandem repeat in bacterial signalling proteins. Family includes CoxC and CoxH from P.carboxydovorans. Each repeat contains two transmembrane helices. Domain is also described as the MHYT domain.
Pssm-ID: 427453 [Multi-domain] Cd Length: 54 Bit Score: 46.43 E-value: 6.80e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 497562044 183 CAIVGMHYTGMAAAQFPLGSFCGAAGRGIDngwlavLVIVITLAVIAIALIVSVLDSRL 241
Cdd:pfam03707 1 LGIWSMHFIGMLAFRLPGPIGYDPALTALS------LVIAVVASGAALWLAFRRRDTRL 53
|
|
| YuxH |
COG3434 |
c-di-GMP phosphodiesterase YuxH/PdeH, contains EAL and HDOD domains [Signal transduction ... |
552-679 |
4.40e-06 |
|
c-di-GMP phosphodiesterase YuxH/PdeH, contains EAL and HDOD domains [Signal transduction mechanisms];
Pssm-ID: 442660 [Multi-domain] Cd Length: 407 Bit Score: 49.42 E-value: 4.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 552 LEPSHLILEVTESTAmrdADASLV-ILEQLSAMGVGISIDDF--GTGYSSLLYLkrlpASELKIDrgFineLAHDSDDAA 628
Cdd:COG3434 81 LPPERVVLEILEDVE---PDEELLeALKELKEKGYRIALDDFvlDPEWDPLLPL----ADIIKID--V---LALDLEELA 148
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 497562044 629 ivsAIVALGRTLNLKIVAEGVETEAQQEFLTRLGCNSLQGFLLGRPMPAEQ 679
Cdd:COG3434 149 ---ELVARLKRYGIKLLAEKVETREEFELCKELGFDLFQGYFFSKPEILKG 196
|
|
| MASE1 |
COG3447 |
Integral membrane sensor domain MASE1 [Signal transduction mechanisms]; |
157-564 |
1.06e-03 |
|
Integral membrane sensor domain MASE1 [Signal transduction mechanisms];
Pssm-ID: 442670 [Multi-domain] Cd Length: 637 Bit Score: 42.10 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 157 LWIAFRLRhgsrrivlVRAGAALVMGCAIVGMhyTGMAAAQFPLGSfcGAAGRGIDNGWLAVLVIVITLAVIAiALIVSV 236
Cdd:COG3447 227 LWAALRFG--------LRGAALAVLLLALIAI--LATALGLGPFAS--LSPNQSLLLLQLFLAVLALTGLLLA-AALAER 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 237 LDSRLEARTSVLATSLARANRELIQLALHDNLTKLPNRMLLDDRLEQAIQQAIRDDRRFAVLFMDLDGFKAVNDAYGHHL 316
Cdd:COG3447 294 RRQRLRERELALRAALELLALGLLLAALDDALLLLNARGLLLLALSLAALLLLRLALLLLLLALDALLLLLADDDRGELR 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 317 GDLLL-IEVAERIRANVRAQDTIARLGGDEFVLLIEAREPADAATLAEKLVKRISQPYQISRHEVRISASIGIALYPGDG 395
Cdd:COG3447 374 GDLLRrRGATRLGAVVARLLRRSGGRGEEVVVLLVIAQVEEALELALRERREERLLERLALALELLAITAALLAAALLLA 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 396 QTRHELMINADAAMYHAKDQGRNGYCFFESSMNANAQEQLQLLHDLRQALERR---QLVLHYQPKVLAPNGPMIGVEALL 472
Cdd:COG3447 454 LADLLLLLLAEAAQLLARALLLGLDRLLADAALAALAALADLLGALLSAGLRRrggRRLGARLIRSLLSRVLAELGAVEL 533
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 473 RWEHPQHGLITPGQFLPLAEKTGLIVQIGEWVLDEACRQMRLWLDGGHAEWNIAVNLSALQFAHAGLVDSVRNALLRHSL 552
Cdd:COG3447 534 LLALIADLTEVALGAEALERLLERLLLALLGLGLAVAALLATLGLLLALLAALALSGAAALLALGAALLLAAAILGLAAA 613
|
410
....*....|..
gi 497562044 553 EPSHLILEVTES 564
Cdd:COG3447 614 LLALLRLLGERA 625
|
|
| PRK11596 |
PRK11596 |
cyclic-di-GMP phosphodiesterase; Provisional |
589-680 |
8.00e-03 |
|
cyclic-di-GMP phosphodiesterase; Provisional
Pssm-ID: 183222 [Multi-domain] Cd Length: 255 Bit Score: 38.83 E-value: 8.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497562044 589 IDDFGTG---YSSLLYLKRlpaSELKIDRGFINELAHDSDDAAIVSAIVALGRTLNLKIVAEGVETEAQQEFLTRLGCNS 665
Cdd:PRK11596 157 LDDFGTGmanFSALSEVRY---DYIKVARELFIMLRQSEEGRNLFSQLLHLMNRYCRGVIVEGVETPEEWRDVQRSPAFA 233
|
90
....*....|....*
gi 497562044 666 LQGFLLGRPMPAEQL 680
Cdd:PRK11596 234 AQGYFLSRPAPFETL 248
|
|
| |
