|
Name |
Accession |
Description |
Interval |
E-value |
| TonB_sider_MxcH |
NF038079 |
TonB-dependent siderophore myxochelin receptor MxcH; |
108-783 |
2.05e-131 |
|
TonB-dependent siderophore myxochelin receptor MxcH;
Pssm-ID: 468337 [Multi-domain] Cd Length: 796 Bit Score: 409.74 E-value: 2.05e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 108 VEVYGKTQTQKVKEGAFAVNALDIKPIVNSLNNLNDLVNRTTGIKVREEGGVGSDFDLSINGLSGNSIRYFLDGMPLDTK 187
Cdd:NF038079 122 VTVRGESEAERRRQSAEAVQVVETERAQREAADLGEVLARTEGVGVRRSGGLGSRARFSLNGLTDDQIRFFLDGVPLELA 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 188 GSGVSLANLPINIIDRIEIYKGVVPASLGTDALGGAINIITKQ-EKKNYLDVSYGIGSFHTHKTDLNTQFVEKGTGLIVR 266
Cdd:NF038079 202 GYGFGLANVPVNLVQRVEVYRGVVPVRFGADALGGAVNLVTDQdVRGTGASASYQLGSFGTHRLTLSGRHLHEPSGFFVR 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 267 PTVGINYSKNDYRMkNVQMRDESGdNFIYGNPKRFHDGYFSLLAQVEAGFVNKSWADAFFVSASYSKTDKELQTGSVQNK 346
Cdd:NF038079 282 ASGFFDTARNDYPI-DVEVPDDLG-RLSPARVPRFHDAYRAGGGGVEVGFVDRPWARRLLLRAFLSGYDKELQHNLVMTV 359
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 347 VYGMAERNSDSWNISARYQKynFILKNMQLNASLSHTWDHSLTVDTAYRKYYWDGGYIVS--QRNEIMGKePSMRHYKRP 424
Cdd:NF038079 360 PYGEVTYGETSAGATLRYEQ--TFGRGLRVDAVAGYTFRRTRFLDLSTCVYDWYGRCVRTrpQPGEIESR-AVDQTVWQH 436
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 425 LTIMRTNLDYQLNTHHSFNLNY---HLSRTGNDRFDDLDTSFEP---SKDVVTKhILGLSYNQSLLDGKMENVFFIKDYI 498
Cdd:NF038079 437 TGFARLNLGWTLAPEHTLRLSVaptFVARTGEDRRLRAPGQRDPltaDRDLFSL-VTGLEYELDAFDGRLENIAFVKDYL 515
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 499 NhpniRQTDQSSVTGSKDVQGSTTKNYLGYGAGLRYTIVEPLSIKVSYEHSVRLPIARELLGNGTTIYANVALKPENSNN 578
Cdd:NF038079 516 Q----RARAEELLASGTFRPLDRDTHRLGVGDSLRFRLTPWLYAKASYEWATRLPRPDELFGDGVLIVENLDLEPETSHN 591
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 579 FNASLFGTWHPGNGHTFYYEMSGFFRKVNNYIQtsIAEKEGTMQYTNVPAVHVKGVEGEIRYDWQGR-LQLSTNVSYQDT 657
Cdd:NF038079 592 VNLGLTLDPLRTPAGSFRANVNGFARLADQLIV--LLGRDSYFTYQNVYAARSLGVEGAAGWTSPGQyLSLDGNVTWQDF 669
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 658 RDQQkykGDGKPSATYNNRVPNRPWLFGSVEAYYTFRNIALPESRLRLGCTYQWVHWYFLTWEAYGSYDNKARIPAQHIC 737
Cdd:NF038079 670 RNTS---SEGTFGAFEGDRIPNRPWLFANGSARFQLSGLASPRDELSLTWTTRYVHEFFRGWESLGAAGSKQVIPSQLLH 746
|
650 660 670 680
....*....|....*....|....*....|....*....|....*...
gi 496329366 738 NADITYSWRRGRYNLA--LECTNFLDKTAYDNYKLQKPGRAFFAKFRL 783
Cdd:NF038079 747 SLALTYVVRDGRATLSwtAEVQNLTDARAFDFFGVQRPGRALFAKLTL 794
|
|
| FepA |
COG4771 |
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ... |
93-748 |
1.14e-49 |
|
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];
Pssm-ID: 443803 [Multi-domain] Cd Length: 612 Bit Score: 185.06 E-value: 1.14e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 93 KQNFTLQESAVALNSVEVYGKTQTQKVKEGAFAVNALDIKPIVNS-LNNLNDLVNRTTGIKVREEGGVGSDFDLSINGLS 171
Cdd:COG4771 15 QAADALAEDATELEEVVVTATRTEQSLSDAPASVSVITAEEIEKLgATDLADALRLLPGVSVTRSGGRGGSSGISIRGLG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 172 GNSIRYFLDGMPLDT--KGSGVSLANLPINIIDRIEIYKGVVPASLGTDALGGAINIITKQEKKNY---LDVSYGIGSFH 246
Cdd:COG4771 95 GDRVLVLIDGVPVNNpaLGGGGDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKKPTDELegsVSLGYGSNGNG 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 247 THKTDLNTQFVEKGTGLivrpTVGINYSKNDYRmknvqmRDESGDNFIYGNPKRFHDGYFSLLAQveagfvnksWADAFF 326
Cdd:COG4771 175 TYSGSLSLGGPGDKLSF----LLSGSYRDRDGY------LDYRNGGFVGNSGYERYNLNAKLGYR---------LSDNHR 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 327 VSASYSKTDKELQTGSVQNKVYGMAERNSDSWNISARYQKYNFilknmqlnaSLSHTWDHSLTVDTAYRKYYWDGGYivs 406
Cdd:COG4771 236 LSLSGGYSRQDRDGGPPTLGDTEISSDNAGDRDTTTDRGNYSL---------RYNGDLGDNLDLSLYYSRTDRDSTN--- 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 407 qrNEIMGKEPSMRHYKRPLTIMRTNLDYQLNTHHSFNLNYHLsrtgndRFDDLDTSFEPSKDVVTKHILGLsynqslldg 486
Cdd:COG4771 304 --GSLGGSTGSFSDSDDTTYGLELDLTYPLGGNHTLTLGAEY------RYDDLDSSSFLGGADASRDTYGL--------- 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 487 kmenvfFIKDyinhpNIRQTDQSSVTG-----SKDVQGSTTKNYLGYGAGLRYTIVEPLSIKVSYEHSVRLPIARELLGN 561
Cdd:COG4771 367 ------FAQD-----EWKLTDKLTLTAglrydYYSTFGASNYTAFSPRLGLRYDLSDNLTLRASYGRGFRAPSLAELYGS 435
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 562 GT-----TIYANVALKPENSNNFNASLFGTWHPGNghtFYYEMSGFFRKVNNYIQTSI--AEKEGTMQYTNVPAVHVKGV 634
Cdd:COG4771 436 GTgtpgrYVLGNPDLKPETSDNYELGLEYRLGNGG---LSLSLTGFYTDIKDLIVLVPvgPGPGDVLQYENVGKARTYGL 512
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 635 EGEIRYDWQGRLQLSTNVSYQDTRDQQkykgdgkpsATYNNRVPNRPWLFGSVEAYYTFRNIALpesrlrlgcTYQWVHW 714
Cdd:COG4771 513 ELELKYRLGKGLTLTASYTYLDSKIDD---------GDTGEPLPNVPPHKANLGLDYRLPKWWL---------LLLLTRY 574
|
650 660 670
....*....|....*....|....*....|....
gi 496329366 715 YFLTWEAYGSYDNKARIPAQHICNADITYSWRRG 748
Cdd:COG4771 575 YGGRYVTPPSGRLEGYTPGYTLLDLRASYKLTKN 608
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
138-782 |
5.82e-45 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 171.48 E-value: 5.82e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 138 LNNLNDLVNRTTGIKVREEGGvGSDFDLSINGLSGNSIRYFLDGMPL--DTKGSGVSLANLPINIIDRIEIYKGVVPASL 215
Cdd:cd01347 15 ATSLADLLRRIPGVSVTRGGG-GGGSTISIRGFGPDRTLVLVDGLPLasSNYGRGVDLNTIPPELIERVEVLKGPSSALY 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 216 GTDALGGAINIITKQEK-KNYLDVSYGIGSFHTHKTDlNTQFVEKG---TGLIVRPTVGINYSKNDyrmknvqmRDESGD 291
Cdd:cd01347 94 GSGAIGGVVNIITKRPTdEFGGSVTAGYGSDNSGSSG-GGGFDVSGalaDDGAFGARLYGAYRDGD--------GTIDGD 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 292 NFIYGNPKRFHDGYFSLLAQVEAGFVnkswadaFFVSASYSKTDKE--------LQTGSVQNKVYGMAERNSDSWNISAR 363
Cdd:cd01347 165 GQADDSDEERYNVAGKLDWRPDDDTR-------LTLDAGYQDQDADgpggtlpaNGTGSSLGGGPSSNTNGDRDWDYRDR 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 364 YQKYNFILKNMQLNaslshTWDHSLTVDTAYRKYYwdggyiVSQRNEIMGKEPSMRHYKRPLTIMRTNLDYqlnTHHSFN 443
Cdd:cd01347 238 YRKRASLGLEHDLN-----DTGWTLRANLSYSYTD------NDGDPLILNGGNNAAGGDLGRSGYSSERDT---TQLGFD 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 444 LNYhlsrtgNDRFDDLDTSFEPSkdvvtkhiLGLSYNQSLLDGKMENVFFIKDY-----------INHPNIRQTDQSSVT 512
Cdd:cd01347 304 AGL------NAPFGTGPVAHTLT--------LGVEYRREELDEKQTALYAQDTIeltddltltlgLRYDHYDQDSKDTIA 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 513 GSKDVQGSTTkNYLGYgAGLRYTIVEPLSIKVSYEHSVRLPIARELLGNG----TTIYANVALKPENSNNFNASLfgTWH 588
Cdd:cd01347 370 GGTTAKKSYS-HWSPS-LGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGshggTAAVGNPNLKPEKSKQYELGL--KYD 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 589 PGNGhtFYYEMSGFFRKVNNYIQTS--IAEKEGTMQYTNVPAVHVKGVEGEIRYDWQGRLQLSTNVSYQDTRDQQKYKGD 666
Cdd:cd01347 446 PGDG--LTLSAALFRIDIKNEIVSTptNTGLGLVTVYVNGGKARIRGVELEASYDLTDGLGLTGSYTYTDTEVKRTDGAT 523
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 667 GkpsatyNNRVPNRPWLFGSVEAYYTFrnialPESRLRLGCTYQWVHWYFLTWEAygsYDNKARIPAQHICNADITYSWR 746
Cdd:cd01347 524 T------GNRLPGIPKHTANLGLDYEL-----PDEGLTAGGGVRYRGKQYADTAN---GNNTVKVPGYTLVDLSASYQFT 589
|
650 660 670 680
....*....|....*....|....*....|....*....|....
gi 496329366 747 RGrYNLALECTNFLDKTAYDN--------YKLQKPGRAFFAKFR 782
Cdd:cd01347 590 KN-LTLRLGVNNLFDKDYYTSlsvrgsglYGYYGPGRTYYLSVS 632
|
|
| CarbopepD_reg_2 |
pfam13715 |
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ... |
27-110 |
2.20e-20 |
|
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.
Pssm-ID: 433425 [Multi-domain] Cd Length: 88 Bit Score: 86.11 E-value: 2.20e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 27 LSGKVIDQH-GTPIAQATIAVENTTSGTYTDDRGKYSLQVAP-GKHTFVVSFLGYQTVKQSLDIRQD--KKQNFTLQESA 102
Cdd:pfam13715 1 ISGTVVDENtGEPLPGATVYVKGTTKGTVTDADGNFELKNLPaGTYTLVVSFVGYKTQEKKVTVSNDntLDVNFLLKEDA 80
|
....*...
gi 496329366 103 VALNSVEV 110
Cdd:pfam13715 81 LLLDEVVV 88
|
|
| TonB-hemin |
TIGR01785 |
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ... |
105-777 |
2.67e-20 |
|
TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273807 [Multi-domain] Cd Length: 665 Bit Score: 95.92 E-value: 2.67e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 105 LNSVEVYGKTQTQKVKEGAFAVNALDIKPIV-NSLNNLNDLVNRTTGIKVREeGGVGSDFDLSINGLSGNSIRYFLDGMP 183
Cdd:TIGR01785 1 LDTVTVTATRTRQVLSEAPASVSVISGEQIEsKQANNLADALNTVPGVDVTG-GGRPPGQSINIRGLQDNRVLVVVDGAR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 184 L--DTKGSGVSLANLPINIIDRIEIYKGVVPASLGTDALGGAINIITK------QEKKNY-LDVSYGIGSFhthktDLNT 254
Cdd:TIGR01785 80 QnyQRGGAHNGSLFVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKdaadllRPGQLFgGLAKLSYGSN-----NNSF 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 255 QFVEKGTGLIVRPTVG-INYSKNDyrMKNvqMRDESGDNFIYgnpkrfhDGY--FSLLAQVEagfvnkSWADAffvsasy 331
Cdd:TIGR01785 155 GGSVAVAGRLDDNLDAlVAATYRD--GGN--YRNGNKEEATN-------SAYvqKNLLAKLG------WQLDD------- 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 332 sktDKELQTGSVQNKVygmaernsdSWNI-SARYQKYNFILknmqlnaSLSHTWDHSLTVD-TAYRKYYW---DGGYI-- 404
Cdd:TIGR01785 211 ---AQRLEFSYFTTEG---------SLDEaQNSGPGTEYVL-------GSSSTLLASSTRDrSATLTYNWtpeDNPWLda 271
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 405 ---VSQRNEIMGKEPSMRHYKRPLTIMRTNLDYQLNTHHSFNLNYHLSRT-GNDRFDDLDT--SFEPSKDVvtkhilglS 478
Cdd:TIGR01785 272 tasLYYNRTENDNDRSARGVGREEGYQYTTYGATLQNTSRFDVASWSTLTyGVDWMKDKRRteSFDPNSVT--------T 343
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 479 YNQSLLDGK-MENVFFIKDYINHPNIRQT----------DQSSVTGSKDVQGSTTKNYLGYGAGLRYTIVEPLSIKVSYE 547
Cdd:TIGR01785 344 IVPNPPSAKeYFFGLFLQDNIPLLDDRLTlsaglrydhyKLSPKTTADTEAVDRSYSRWSPSLGLSYKPVDWLTLYASYS 423
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 548 HSVRLPIARELLGNGT--------TIYANVALKPENSNN----FNASLFGTWHpgNGHTFYYEMSGFFRKVNNYIQTSI- 614
Cdd:TIGR01785 424 QGFRAPSIDELYGTGDhpgtpggyTFAPNPNLKPETSKTwelgANLSFDNLLL--DNDQLQFKVAYFYNDVKDFIDLTIg 501
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 615 ------AEKEGTMQYTNVPAVHVKGVEGEIRYDWqGRLQLSTNVSYQDTRDQQKYKGDG-----KPSATYNNRVPNRPWL 683
Cdd:TIGR01785 502 vtdnvtAGMNNITQYVNIDGARIRGIEASASYDA-GLWATGLSYGYTIGKDQNTNQWLSnipplKLVVTVGYRFPDRRLD 580
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 684 FGSVEAYYtfrnialpESRLRLGCTYQWVHWYFLTWEAYGSYDNKAripaqhicnadiTYSWRRGRY---NLALEctNFL 760
Cdd:TIGR01785 581 LGAKAAYY--------ERQSESPTTEDVAANGLLTTPGYTVVDLYA------------TYQPNAVKGltvRFGVN--NLT 638
|
730
....*....|....*....
gi 496329366 761 DK--TAYDNYKLQKPGRAF 777
Cdd:TIGR01785 639 DRkyTPAQSVPGAGPGRNF 657
|
|
| TonB_dep_Rec |
pfam00593 |
TonB dependent receptor; This model now only covers the conserved part of the barrel structure. |
315-783 |
1.69e-19 |
|
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain] Cd Length: 475 Bit Score: 92.53 E-value: 1.69e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 315 GFVNKSWADAFFVSASYSKTDKELQTGSVQNKVYGMAERNSDSWNISARYQkynfilknmqLNASLSHTWDHSLTVDTAY 394
Cdd:pfam00593 18 GYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYD----------YDLGDGLSWLSTLRLGLRY 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 395 RKYYWDGGYIVSQRNEIMGKEPSMRHYKRPLTIMRTNLDYQLNTHHSFNLNYHLSRTGNDRFDDLDTSFEPSKDVVTKHI 474
Cdd:pfam00593 88 SSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPANPSSSSY 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 475 LGLSYNQSLLDGkMENVFFIKDYINHPNIRQTDQSSVTGSKDVQGSTTKNYLG---YGAGLRYTIVEPLSIKVSYEHSVR 551
Cdd:pfam00593 168 SDTTTDSYGLYL-QDNIKLTDRLTLTLGLRYDHYSTDGDDGNGGGDNFSRSYSafsPRLGLVYKPTDNLSLYASYSRGFR 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 552 LPIAREL------LGNGTTIYANVALKPENSNNFNASLfgTWHPGNghtFYYEMSGFFRKVNNYIQTS---IAEKEGTMQ 622
Cdd:pfam00593 247 APSLGELygsgsgGGGGAVAGGNPDLKPETSDNYELGL--KYDDGR---LSLSLALFYIDIKNLITSDpdgPGLGGTVYT 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 623 YTNVPAVHVKGVEGEIRYDWQGRLQLSTNVSYQDTRDQQKYKGDGkpsatynNRVPNRPWLFGSVEAYYTFRNIALpesR 702
Cdd:pfam00593 322 YTNVGKARIRGVELELSGRLWGLGLSGGGYTYTDADDDADADDTG-------NPLPNVPRHTANLGLTYDFPLGGW---G 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 703 LRLGCTYQWVhwyflTWEAYGSYDNKARIPAQHICNADITYSWRRgRYNLALECTNFLDKTAYDNYKLQK--------PG 774
Cdd:pfam00593 392 ARLGARYVGS-----GERRYGDAANTFKTPGYTLVDLSAGYRLNK-NLTLRLGVNNLFDKYYKRYYSSGGgnlggypgPG 465
|
....*....
gi 496329366 775 RAFFAKFRL 783
Cdd:pfam00593 466 RTFYLGLSY 474
|
|
| PRK13484 |
PRK13484 |
IreA family TonB-dependent siderophore receptor; |
60-669 |
5.29e-13 |
|
IreA family TonB-dependent siderophore receptor;
Pssm-ID: 139605 [Multi-domain] Cd Length: 682 Bit Score: 72.73 E-value: 5.29e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 60 KYSLQVAPGKHTFVVSFL--GYQTVKQSLDIRQDKKQNFTlQESAVALNSVEVYGKTQTQKvkegafavnaldiKPIvns 137
Cdd:PRK13484 2 KNKYIIAPGIAVMCSAVIssGYASSDKKEDTLVVTASGFT-QQLRNAPASVSVITSEQLQK-------------KPV--- 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 138 lNNLNDLVNRTTGIKVReegGVGSDFDLSINGLSGNSIRYFLDGMPLDTK-----GSGVSLANL--PINIIDRIEIYKGV 210
Cdd:PRK13484 65 -SDLVDAVKDVEGISIT---GGNEKPDISIRGLSGDYTLILVDGRRQSGResrpnGSGGFEAGFipPVEAIERIEVIRGP 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 211 VPASLGTDALGGAINIITKQEKKNYLDVSYGIGSFHTHKTDLNtqfvekgtglivrptvgiNYSKNDYRMKNVQMRDESG 290
Cdd:PRK13484 141 MSSLYGSDAIGGVINIITKPVNNQTWDGVLGLGGIIQEHGKFG------------------NSTTNDFYLSGPLIKDKLG 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 291 DNfIYGnpkrfhdgyfsllaqveagfvnkswadaffvSASYSKTDKELQ-TGSVQNKvygmaernsdswNISARYQ---- 365
Cdd:PRK13484 203 LQ-LYG-------------------------------GMNYRKEDSISQgTPAKDNK------------NITATLQftpt 238
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 366 -KYNFIL---KNMQLnaslshtwdHSLTVDTAYRKYYWDGGYIvsQRNEIMGKEPSMRH----YKRPLTIMRTNLD-YQL 436
Cdd:PRK13484 239 eSQKFVFeygKNNQV---------HTLTPGESLDAWTMRGNLK--QPNSKRETHNSRSHwvaaWNAQGEILHPEIAvYQE 307
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 437 NTHHSfnlnyhLSRTGNDRFDDLDTSFEPSKDVVTKHILGLSYNQSLLDgkmeNVFFIKDYINHPNIRqtDQSSvTGSKD 516
Cdd:PRK13484 308 KVIRE------VKSGKKDKYNHWDLNYESRKPEITNTIIDAKVTAFLPE----NVLTIGGQFQHAELR--DDSA-TGKKT 374
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 517 VQGST---------------TKNYLGYGAGLR------------------YTIVEPLSIKVSYEHSVRLPIARELL-GNG 562
Cdd:PRK13484 375 TETQSvsikqkavfieneyaATDSLALTGGLRldnheiygsywnprlyavYNLTDNLTLKGGIAKAFRAPSIREVSpGFG 454
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 563 TT-------IYANVALKPE------------NSNNF--NASLFGTwhpgnghtfyyemsGFFRKVNNYIQTSIAEKEG-- 619
Cdd:PRK13484 455 TLtqggasiMYGNRDLKPEtsvteeigiiysNDSGFsaSATLFNT--------------DFKNKLTSYDIGTKDPVTGln 520
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*.
gi 496329366 620 TMQYTNVPAVHVKGVEGEIRYDWQGRLQLSTNVSYQDTR---DQQKYKGD---GKP 669
Cdd:PRK13484 521 TFIYDNVGEANIRGVELATQIPVYDKWHVSANYTFTDSRrksDDESLNGKslkGEP 576
|
|
| Peptidase_M14NE-CP-C_like |
cd11308 |
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, ... |
29-98 |
1.08e-06 |
|
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; This domain is found C-terminal to the M14 carboxypeptidase (CP) N/E subfamily containing zinc-binding enzymes that hydrolyze single C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. The N/E subfamily includes enzymatically active members (carboxypeptidase N, E, M, D, and Z), as well as non-active members (carboxypeptidase-like protein 1, -2, aortic CP-like protein, and adipocyte enhancer binding protein-1) which lack the critical active site and substrate-binding residues considered necessary for activity. The active N/E enzymes fulfill a variety of cellular functions, including prohormone processing, regulation of peptide hormone activity, alteration of protein-protein or protein-cell interactions and transcriptional regulation. For M14 CPs, it has been suggested that this domain may assist in folding of the CP domain, regulate enzyme activity, or be involved in interactions with other proteins or with membranes; for carboxypeptidase M, it may interact with the bradykinin 1 receptor at the cell surface. This domain may also be found in other peptidase families.
Pssm-ID: 200604 [Multi-domain] Cd Length: 76 Bit Score: 46.75 E-value: 1.08e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 496329366 29 GKVIDQHGTPIAQATIAVENTTSGTYTDDRGKYSLQVAPGKHTFVVSFLGYQTVKQSLDIRQDKK---QNFTL 98
Cdd:cd11308 4 GFVTDATGNPIANATISVEGINHDVTTAKDGDYWRLLLPGTYNVTASAPGYQPVTKTVTVPNNFSatvVNFTL 76
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| TonB_sider_MxcH |
NF038079 |
TonB-dependent siderophore myxochelin receptor MxcH; |
108-783 |
2.05e-131 |
|
TonB-dependent siderophore myxochelin receptor MxcH;
Pssm-ID: 468337 [Multi-domain] Cd Length: 796 Bit Score: 409.74 E-value: 2.05e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 108 VEVYGKTQTQKVKEGAFAVNALDIKPIVNSLNNLNDLVNRTTGIKVREEGGVGSDFDLSINGLSGNSIRYFLDGMPLDTK 187
Cdd:NF038079 122 VTVRGESEAERRRQSAEAVQVVETERAQREAADLGEVLARTEGVGVRRSGGLGSRARFSLNGLTDDQIRFFLDGVPLELA 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 188 GSGVSLANLPINIIDRIEIYKGVVPASLGTDALGGAINIITKQ-EKKNYLDVSYGIGSFHTHKTDLNTQFVEKGTGLIVR 266
Cdd:NF038079 202 GYGFGLANVPVNLVQRVEVYRGVVPVRFGADALGGAVNLVTDQdVRGTGASASYQLGSFGTHRLTLSGRHLHEPSGFFVR 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 267 PTVGINYSKNDYRMkNVQMRDESGdNFIYGNPKRFHDGYFSLLAQVEAGFVNKSWADAFFVSASYSKTDKELQTGSVQNK 346
Cdd:NF038079 282 ASGFFDTARNDYPI-DVEVPDDLG-RLSPARVPRFHDAYRAGGGGVEVGFVDRPWARRLLLRAFLSGYDKELQHNLVMTV 359
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 347 VYGMAERNSDSWNISARYQKynFILKNMQLNASLSHTWDHSLTVDTAYRKYYWDGGYIVS--QRNEIMGKePSMRHYKRP 424
Cdd:NF038079 360 PYGEVTYGETSAGATLRYEQ--TFGRGLRVDAVAGYTFRRTRFLDLSTCVYDWYGRCVRTrpQPGEIESR-AVDQTVWQH 436
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 425 LTIMRTNLDYQLNTHHSFNLNY---HLSRTGNDRFDDLDTSFEP---SKDVVTKhILGLSYNQSLLDGKMENVFFIKDYI 498
Cdd:NF038079 437 TGFARLNLGWTLAPEHTLRLSVaptFVARTGEDRRLRAPGQRDPltaDRDLFSL-VTGLEYELDAFDGRLENIAFVKDYL 515
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 499 NhpniRQTDQSSVTGSKDVQGSTTKNYLGYGAGLRYTIVEPLSIKVSYEHSVRLPIARELLGNGTTIYANVALKPENSNN 578
Cdd:NF038079 516 Q----RARAEELLASGTFRPLDRDTHRLGVGDSLRFRLTPWLYAKASYEWATRLPRPDELFGDGVLIVENLDLEPETSHN 591
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 579 FNASLFGTWHPGNGHTFYYEMSGFFRKVNNYIQtsIAEKEGTMQYTNVPAVHVKGVEGEIRYDWQGR-LQLSTNVSYQDT 657
Cdd:NF038079 592 VNLGLTLDPLRTPAGSFRANVNGFARLADQLIV--LLGRDSYFTYQNVYAARSLGVEGAAGWTSPGQyLSLDGNVTWQDF 669
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 658 RDQQkykGDGKPSATYNNRVPNRPWLFGSVEAYYTFRNIALPESRLRLGCTYQWVHWYFLTWEAYGSYDNKARIPAQHIC 737
Cdd:NF038079 670 RNTS---SEGTFGAFEGDRIPNRPWLFANGSARFQLSGLASPRDELSLTWTTRYVHEFFRGWESLGAAGSKQVIPSQLLH 746
|
650 660 670 680
....*....|....*....|....*....|....*....|....*...
gi 496329366 738 NADITYSWRRGRYNLA--LECTNFLDKTAYDNYKLQKPGRAFFAKFRL 783
Cdd:NF038079 747 SLALTYVVRDGRATLSwtAEVQNLTDARAFDFFGVQRPGRALFAKLTL 794
|
|
| FepA |
COG4771 |
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ... |
93-748 |
1.14e-49 |
|
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];
Pssm-ID: 443803 [Multi-domain] Cd Length: 612 Bit Score: 185.06 E-value: 1.14e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 93 KQNFTLQESAVALNSVEVYGKTQTQKVKEGAFAVNALDIKPIVNS-LNNLNDLVNRTTGIKVREEGGVGSDFDLSINGLS 171
Cdd:COG4771 15 QAADALAEDATELEEVVVTATRTEQSLSDAPASVSVITAEEIEKLgATDLADALRLLPGVSVTRSGGRGGSSGISIRGLG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 172 GNSIRYFLDGMPLDT--KGSGVSLANLPINIIDRIEIYKGVVPASLGTDALGGAINIITKQEKKNY---LDVSYGIGSFH 246
Cdd:COG4771 95 GDRVLVLIDGVPVNNpaLGGGGDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKKPTDELegsVSLGYGSNGNG 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 247 THKTDLNTQFVEKGTGLivrpTVGINYSKNDYRmknvqmRDESGDNFIYGNPKRFHDGYFSLLAQveagfvnksWADAFF 326
Cdd:COG4771 175 TYSGSLSLGGPGDKLSF----LLSGSYRDRDGY------LDYRNGGFVGNSGYERYNLNAKLGYR---------LSDNHR 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 327 VSASYSKTDKELQTGSVQNKVYGMAERNSDSWNISARYQKYNFilknmqlnaSLSHTWDHSLTVDTAYRKYYWDGGYivs 406
Cdd:COG4771 236 LSLSGGYSRQDRDGGPPTLGDTEISSDNAGDRDTTTDRGNYSL---------RYNGDLGDNLDLSLYYSRTDRDSTN--- 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 407 qrNEIMGKEPSMRHYKRPLTIMRTNLDYQLNTHHSFNLNYHLsrtgndRFDDLDTSFEPSKDVVTKHILGLsynqslldg 486
Cdd:COG4771 304 --GSLGGSTGSFSDSDDTTYGLELDLTYPLGGNHTLTLGAEY------RYDDLDSSSFLGGADASRDTYGL--------- 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 487 kmenvfFIKDyinhpNIRQTDQSSVTG-----SKDVQGSTTKNYLGYGAGLRYTIVEPLSIKVSYEHSVRLPIARELLGN 561
Cdd:COG4771 367 ------FAQD-----EWKLTDKLTLTAglrydYYSTFGASNYTAFSPRLGLRYDLSDNLTLRASYGRGFRAPSLAELYGS 435
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 562 GT-----TIYANVALKPENSNNFNASLFGTWHPGNghtFYYEMSGFFRKVNNYIQTSI--AEKEGTMQYTNVPAVHVKGV 634
Cdd:COG4771 436 GTgtpgrYVLGNPDLKPETSDNYELGLEYRLGNGG---LSLSLTGFYTDIKDLIVLVPvgPGPGDVLQYENVGKARTYGL 512
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 635 EGEIRYDWQGRLQLSTNVSYQDTRDQQkykgdgkpsATYNNRVPNRPWLFGSVEAYYTFRNIALpesrlrlgcTYQWVHW 714
Cdd:COG4771 513 ELELKYRLGKGLTLTASYTYLDSKIDD---------GDTGEPLPNVPPHKANLGLDYRLPKWWL---------LLLLTRY 574
|
650 660 670
....*....|....*....|....*....|....
gi 496329366 715 YFLTWEAYGSYDNKARIPAQHICNADITYSWRRG 748
Cdd:COG4771 575 YGGRYVTPPSGRLEGYTPGYTLLDLRASYKLTKN 608
|
|
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
105-768 |
1.64e-48 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 181.95 E-value: 1.64e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 105 LNSVEVYGKTQTQKVKEGAFAVNALDIKPIVN-SLNNLNDLVNRTTGIKVREEGGVGSDFdlSINGLSG--NSIRYFLDG 181
Cdd:COG1629 1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDqPATDLGDLLRRVPGVSVTSAGGGAGQI--SIRGFGGggNRVLVLVDG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 182 MPL-DTKGSGVSLANLPINIIDRIEIYKGVVPASLGTDALGGAINIITKQ-EKKNYLDVSYGIGSFHTHKTDLntqfvek 259
Cdd:COG1629 79 VPLnDPSGGDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKpKDGKGGEVSASYGSYGTYRASL------- 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 260 gtglivrpTVGINYSKNDYRmknVQMRDESGDNFIYGNPKRFHDGYFSLLAQveagfvnksWADAFFVSASYSKTDKELQ 339
Cdd:COG1629 152 --------SLSGGNGKLAYR---LSASYRDSDGYRDNSDSDRYNLRAKLGYQ---------LGDDTRLTLSASYSDSDQD 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 340 TGSVQNKVYGMAERNSDSWNISARYQKYNFILKNMQLNASLSHTWD-HSLTVDTAYRKYYWDGGYIVSQRNEIMGKEPSM 418
Cdd:COG1629 212 SPGYLTLAALRPRGAMDDGTNPYSNDTDDNTRDRYSLSLEYEHLGDgLKLSASAYYRYDDTDLDSDFTPTPADGGTLEQT 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 419 RHYKRpltimRTNLDYQLNTHHSFNLNYHLsRTGNDRFDDLDTSFEPSKDVVTKHILGLSYNQSLLDGKMENVFFIKDYI 498
Cdd:COG1629 292 DFDNR-----TYGLELRLTYDLGFGGKHTL-LVGLDYQRQDLDGSGYPLDLGSGSLPTLTSGADDDGTTTSLALYAQDTY 365
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 499 N------------HPNIRQTDQSSVTGSKDVQGSTTKNYLGYGAGLRYTIVEPLSIKVSYEHSVRLPIARELLGNGTTIY 566
Cdd:COG1629 366 KltdkltltaglrYDYVSYDVDDTVTGTDSASGSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGELYANGTDPY 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 567 --ANVALKPENSNNFNASLFGTWhpgNGHTFYYEMSGFFRKVNNYI--QTSIAEKEGTMQYTNVPAVHVKGVEGEIRYDW 642
Cdd:COG1629 446 svGNPDLKPETSTNYELGLRYRL---LDGRLSLSLALFYSDVDNEIlsVPLPNDSGFSTYYTNAGKARSYGVELELSYQL 522
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 643 QGRLQLSTNVSYQDTrdqqKYKGDGKPSATY-NNRVPNRPWLFGSVEAYYTFRNialpesRLRLGCTYQWVHWYfltwea 721
Cdd:COG1629 523 TPGLSLNASYSYTDA----KFDDDTDGSADLdGNRLPGVPPLTANLGLTYEFPG------GWSLGLGVRYVGDR------ 586
|
650 660 670 680
....*....|....*....|....*....|....*....|....*...
gi 496329366 722 YGSYDNKARIP-AQHICNADITYSWRRgRYNLALECTNFLDKTAYDNY 768
Cdd:COG1629 587 YLDDANTQGAPgGYTLVDLGAGYRFGD-NLTLSLGVDNLFDKKYATSL 633
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
138-782 |
5.82e-45 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 171.48 E-value: 5.82e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 138 LNNLNDLVNRTTGIKVREEGGvGSDFDLSINGLSGNSIRYFLDGMPL--DTKGSGVSLANLPINIIDRIEIYKGVVPASL 215
Cdd:cd01347 15 ATSLADLLRRIPGVSVTRGGG-GGGSTISIRGFGPDRTLVLVDGLPLasSNYGRGVDLNTIPPELIERVEVLKGPSSALY 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 216 GTDALGGAINIITKQEK-KNYLDVSYGIGSFHTHKTDlNTQFVEKG---TGLIVRPTVGINYSKNDyrmknvqmRDESGD 291
Cdd:cd01347 94 GSGAIGGVVNIITKRPTdEFGGSVTAGYGSDNSGSSG-GGGFDVSGalaDDGAFGARLYGAYRDGD--------GTIDGD 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 292 NFIYGNPKRFHDGYFSLLAQVEAGFVnkswadaFFVSASYSKTDKE--------LQTGSVQNKVYGMAERNSDSWNISAR 363
Cdd:cd01347 165 GQADDSDEERYNVAGKLDWRPDDDTR-------LTLDAGYQDQDADgpggtlpaNGTGSSLGGGPSSNTNGDRDWDYRDR 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 364 YQKYNFILKNMQLNaslshTWDHSLTVDTAYRKYYwdggyiVSQRNEIMGKEPSMRHYKRPLTIMRTNLDYqlnTHHSFN 443
Cdd:cd01347 238 YRKRASLGLEHDLN-----DTGWTLRANLSYSYTD------NDGDPLILNGGNNAAGGDLGRSGYSSERDT---TQLGFD 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 444 LNYhlsrtgNDRFDDLDTSFEPSkdvvtkhiLGLSYNQSLLDGKMENVFFIKDY-----------INHPNIRQTDQSSVT 512
Cdd:cd01347 304 AGL------NAPFGTGPVAHTLT--------LGVEYRREELDEKQTALYAQDTIeltddltltlgLRYDHYDQDSKDTIA 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 513 GSKDVQGSTTkNYLGYgAGLRYTIVEPLSIKVSYEHSVRLPIARELLGNG----TTIYANVALKPENSNNFNASLfgTWH 588
Cdd:cd01347 370 GGTTAKKSYS-HWSPS-LGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGshggTAAVGNPNLKPEKSKQYELGL--KYD 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 589 PGNGhtFYYEMSGFFRKVNNYIQTS--IAEKEGTMQYTNVPAVHVKGVEGEIRYDWQGRLQLSTNVSYQDTRDQQKYKGD 666
Cdd:cd01347 446 PGDG--LTLSAALFRIDIKNEIVSTptNTGLGLVTVYVNGGKARIRGVELEASYDLTDGLGLTGSYTYTDTEVKRTDGAT 523
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 667 GkpsatyNNRVPNRPWLFGSVEAYYTFrnialPESRLRLGCTYQWVHWYFLTWEAygsYDNKARIPAQHICNADITYSWR 746
Cdd:cd01347 524 T------GNRLPGIPKHTANLGLDYEL-----PDEGLTAGGGVRYRGKQYADTAN---GNNTVKVPGYTLVDLSASYQFT 589
|
650 660 670 680
....*....|....*....|....*....|....*....|....
gi 496329366 747 RGrYNLALECTNFLDKTAYDN--------YKLQKPGRAFFAKFR 782
Cdd:cd01347 590 KN-LTLRLGVNNLFDKDYYTSlsvrgsglYGYYGPGRTYYLSVS 632
|
|
| BtuB |
COG4206 |
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism]; |
108-401 |
6.38e-37 |
|
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
Pssm-ID: 443355 [Multi-domain] Cd Length: 276 Bit Score: 140.01 E-value: 6.38e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 108 VEVYGKTQTQKVKEGAFAVNALDIKPIVNS-LNNLNDLVNRTTGIKVREEGGVGSDFDLSINGLSGNSIRYFLDGMPL-D 185
Cdd:COG4206 1 VVVTATRLEQSKSDLTGSVTVIDAEELERSgATSLADALRRVPGVQVSSSGGPGSAASISIRGLGSNQTLVLIDGVPLnD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 186 TKGSGVSLANLPINIIDRIEIYKGVVPASLGTDALGGAINIITKQEKKNY-LDVSYGIGSFHTHKTDLNTQFVEKGTGLi 264
Cdd:COG4206 81 PSLGGVDLSLIPPDDIERIEVLKGAASALYGSDAIGGVINITTKKGKKGFkGSVSASYGSFGTRRLSASLSGGAGKFSY- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 265 vrpTVGINYSKndyrmknvqmrdesGDNFIYGNP-KRFHDGYFSLLAQVEAGFvnkSWADAFFVSASYSKTDKELQtgsv 343
Cdd:COG4206 160 ---SLSASYRR--------------SDGYRYNDPdLRNNDGYENTSLNARLGY---KLGDNGSLSLSGGYSDSERG---- 215
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 496329366 344 qnkvYGMAERNSDSWNISARYQKYNFILKNMQLNASLSHTWDHSLTVDTAYRKYYWDG 401
Cdd:COG4206 216 ----YPGAVGSDRNLRLSLSLEYKLSDGWSLLLLAYYYYDRDYEDGGGDSAGTSNTDG 269
|
|
| FecA |
COG4772 |
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; |
99-783 |
1.76e-27 |
|
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
Pssm-ID: 443804 [Multi-domain] Cd Length: 681 Bit Score: 118.88 E-value: 1.76e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 99 QESAVALNSVEVYG-KTQTQKVKEGAFAVNALDIKPIVNSL-NNLNDLVNRTTGIKVREEGGVGSDFDLSINGLSGNS-- 174
Cdd:COG4772 17 AEAATTLETVVVTGsRAAEARLKDVPGSVSVVDREELENQAaTSLREVLRRVPGVNVQEEDGFGLRPNIGIRGLGPRRsr 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 175 -IRYFLDGMPL--DTKGSGVSLANLPINIIDRIEIYKGvvPASL--GTDALGGAINIITKQ-EKKNYLDVSYGIGSFHTH 248
Cdd:COG4772 97 gITLLEDGIPIapAPYGDPAAYYFPDLERMERIEVLRG--AAALryGPQTVGGAINFVTRTiPTAFGGELRVTGGSFGYR 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 249 KTDLNTQFVEKGTGLivrpTVGINYSKNDyrmknvQMRDESGDnfiygnpkRFHDGYFSLLAQveagFVNKSWADAFFVS 328
Cdd:COG4772 175 RTHASVGGTVGNFGY----LVEYSRKRGD------GFRDNSGF--------DINDFNAKLGYR----LSDRQELTLKFQY 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 329 ASY------SKTDKELQTGSVQNKvygmaeRNSDSWNISaRYQkynfilknmqlnASLSHTW----DHSLTVDTAYRKYY 398
Cdd:COG4772 233 YDEdantpgGLTDAQFDADPRQSY------RPADQFDTR-RTQ------------LSLRYEHqlsdNTTLTTTAYYNDFS 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 399 WDGGYIVSQRN---EIMGKEPSMRHYKRpLTIMrTNLDYQLNT---HHSFNLNYHLSRTGNDRFDDLDTSFEPSKdvvtk 472
Cdd:COG4772 294 RNWYIRQNTADpntPGLGLRGNPRGYRS-YGIE-PRLTHRFELggvPHTLEVGLRYHREEEDRKQYVNTYGQGRS----- 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 473 hilGLSYNQSLlDGKMENV-FFIKDYIN------------HPNIRQ--TDQSSVTGSKDVQGSTTKNYLGYGAGLRYTIV 537
Cdd:COG4772 367 ---GAGLRRDR-RFSADALaAYAQNRFEltgrltltpglrYEHIRRdrTDRYSTRTGGDDSGSNSYSEFLPGLGLLYQLT 442
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 538 EPLSIKVSYEHSVRLPIARELLGNGTTiyaNVALKPENSNNFNAslfGT-WHPGNGhtFYYEMSGFFRKVNNYIQTSIAE 616
Cdd:COG4772 443 DNLQLYANVSRGFEPPTFGDLAYGNGG---NPDLKPEKSWNYEL---GTrGRIGNG--LSAEVALFYIDYDNELGSCSAA 514
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 617 KEGTMQYTNVPAVHVKGVEGEIRYD----WQGRLQLSTNVSYQDTRdQQKYKGDgkpsATYNNRVPNrpwlfgsveayyt 692
Cdd:COG4772 515 GGDRSTFTNAGETRHQGLELALDYDllkgGGLGLPLFAAYTYTDAE-FTSDFGP----VFAGNRLPY------------- 576
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 693 frniaLPESRLRLGCTYQWVHWYF-LTW----EAYGSYDN------KARIPAQHICNADITYSWRRgRYNLALECTNFLD 761
Cdd:COG4772 577 -----VPRHQLTAGLGYEHGGWTAnLNGryvsEQFTDAANtvadgsFGKIPSYTVLDLSASYDFGK-NLSLFAGVNNLFD 650
|
730 740
....*....|....*....|....*....
gi 496329366 762 KTAY----DNY---KLQKPGRAFFAKFRL 783
Cdd:COG4772 651 KRYIasraPNYaagIRPGPPRTVYAGLRL 679
|
|
| FhuE |
COG4773 |
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ... |
138-768 |
1.11e-23 |
|
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];
Pssm-ID: 443805 [Multi-domain] Cd Length: 692 Bit Score: 106.90 E-value: 1.11e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 138 LNNLNDLVNRTTGIKVREEGGVGSDfDLSINGLSGNSirYFLDGMPLdtkgSGVSLANLPINIIDRIEIYKGvvPASL-- 215
Cdd:COG4773 82 ATTLDDALRNVPGVTVSSYDGGGRD-SFSIRGFSIDN--YLRDGLPL----GGFGGGQPDTANLERVEVLKG--PAGLly 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 216 GTDALGGAINIITKQ-EKKNYLDVSYGIGSFHTHKT--DLNTQFVEKGTgliVRptvginyskndYRMkNVQMRDesGDN 292
Cdd:COG4773 153 GAGSPGGLVNLVTKRpTAEPQGEVSLSAGSWDTYRAtaDVGGPLNEDGT---LR-----------YRL-NAAYED--GDS 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 293 FI-YGNPKRFHdGYFSLLAQVEAGFVnkswadaFFVSASYSKTDKELQTGSVQnkVYGMAERNSDSWNISARYQKYNFil 371
Cdd:COG4773 216 FRdGVDNRRTL-IAPSLDWDLTDDTT-------LTLGAEYQDDDSTGDRGFLP--LDGTLLDLPRSTNLGEPWDYYDT-- 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 372 KNMQLNASLSHTWDHSLTVDTAYR----KYYWDGGYIVSQRNE---IMGKEPSMRHYKRPLTIMRTNLDYQLNT---HHS 441
Cdd:COG4773 284 ETTTLFAELEHRFNDDWSLRANARysdsDRDGRSAYAYGAPDAatgTLTRYASARDGDSRSDSLDANLNGKFETgglEHT 363
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 442 FNLNYHLSRTGNDRFDDLDTS---FEPSKDVVTKHILGLSYNQSLLDgkmENVFFIKDYINHPN-------IRQT--DQS 509
Cdd:COG4773 364 LLVGADYSRYDSDSDSATAGTiniYNPVYGNLPEPDFDASDTDTTTR---QTGLYAQDQISLTDrlslllgGRYDwyETD 440
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 510 SVTGSKDVQGSTTKNYLGYGAGLRYTIVEPLSIKVSYehsvrlpiARELLGNGTTIYANVALKPENSNNFNASLFGTWhP 589
Cdd:COG4773 441 STNRLGGSTTSYDDSAFTPRAGLVYDLTPGLSLYASY--------SESFEPQSGADNNGNPLDPETGKQYEAGVKGEL-F 511
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 590 GNGHTF---YYEMsgffrKVNNYIQTSIAekeGTMQYTNVPAVHVKGVEGEIRYDWQGRLQLSTNVSYQDTrdqqKYKGD 666
Cdd:COG4773 512 DGRLNAtlaVFDI-----TQKNVATTDPD---NPNFYVQVGEVRSRGVELELSGELTPGLNLIAGYTYTDA----KITKD 579
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 667 gkPSATYNNRVPNRPWLFGSVEAYYTFRNIALPESRLRLGCTYQwvhwyfltWEAYGSYDNKARIPAQHICNADITYSWR 746
Cdd:COG4773 580 --ADALEGKRLTNVPRHTASLWTTYRFPSGALKGLGLGGGVRYV--------GERYGDAANTFTLPSYTLVDAGARYDLG 649
|
650 660
....*....|....*....|..
gi 496329366 747 RgRYNLALECTNFLDKTAYDNY 768
Cdd:COG4773 650 K-NWTLQLNVNNLFDKKYYASS 670
|
|
| Fiu |
COG4774 |
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; |
139-767 |
1.81e-20 |
|
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
Pssm-ID: 443806 [Multi-domain] Cd Length: 639 Bit Score: 96.49 E-value: 1.81e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 139 NNLNDLVNRTTGikVREEGGVGSDFD-LSINGLSGNSiRYFLDGMPLDtkgsgvSLANLPINIIDRIEIYKGvvPASL-- 215
Cdd:COG4774 27 TSLADALRNVPG--VTFGAGEGGNGDsFSIRGFSASG-DIYVDGLRDP------GQYRRDTFNLERVEVLKG--PASVly 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 216 GTDALGGAINIITKQ-EKKNYLDVSYGIGSFHTHKT--DLNTQFvekGTGLIVRptvgINYSKNDyrmknvqmrdesGDN 292
Cdd:COG4774 96 GRGSPGGVINLVTKRpTDEPFTEVTLTYGSDGQRRAtlDVNGPL---GDDLAYR----LNGMYRD------------SDS 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 293 FIYGNPKRFHDGYFSLLAQVEAGFVnkswadaFFVSASYSKTDKELQTGsvqnkVYGMAERNSDSWNISARY-QKYNFiL 371
Cdd:COG4774 157 YRDGVDNDRWGIAPSLTWRLGDRTR-------LTLDYEYQDDDRTPDYG-----VPAVANGRPVDVDRSTFYgQPDDY-S 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 372 KNMQLNASLSHTWD----HSLTVDTAYRKYYWDGGYIVSQRNEIMGK---EPSMRHYKRPLTIMRTNLDYQLNT---HHS 441
Cdd:COG4774 224 DSETDSATLRLEHDfndnWTLRNALRYSDYDRDYRNTYPTGGNATGTvtrSAYRRDQDNDTLSNQTDLTGKFDTggvKHT 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 442 FNLNYHLSRTGNDRFDDLDTSFEPSKD----VVTKHILGLSYNQSLLDGKMENV-FFIKDYIN------------HPNIR 504
Cdd:COG4774 304 LLAGVEYSREDSDNARYSGGGTAPTVNlynpVYGAPVTGPTLGGADNDSRTDTTgLYLQDTISltdrwsllaglrYDRFD 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 505 QTDQSSVTGSkdVQGSTTKNYLGYGAGLRYTIVEPLSIKVSYEHSVRLPIarellGNGTTIYANVALKPENSNNFNAslf 584
Cdd:COG4774 384 TDYTDRTTGA--TTSSYDDSAFSPRAGLVYKPTPNLSLYASYSTSFNPGG-----GAPSLSNAGQALDPEKSRQYEV--- 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 585 GT-WHPGNGHTF----YYEMsgffRKVNNYIQTSiaekEGTMQYTNVPAVHVKGVEGEIRYDWQGRLQLSTNVSYQDTRd 659
Cdd:COG4774 454 GVkWDLLDGRLSltaaLFRI----EKTNVRTTDP----ANPGVYVQTGEQRSRGVELEATGELTPGWSVLAGYTYLDAE- 524
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 660 qqkYKGDGKPsATYNNRVPNRPWLFGSVEAYYTFrnialPESRLRLGCTYQWVHwyfltwEAYGSYDNKARIPAQHICNA 739
Cdd:COG4774 525 ---ITKSANA-ANVGNRLPNVPRHSASLWTTYDL-----PLPGLTLGGGVRYVG------SRYADAANTVKLPSYTRFDA 589
|
650 660
....*....|....*....|....*...
gi 496329366 740 DITYSWRRgRYNLALECTNFLDKTAYDN 767
Cdd:COG4774 590 GASYRLNK-NLTLRLNVNNLTDKRYYAS 616
|
|
| CarbopepD_reg_2 |
pfam13715 |
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ... |
27-110 |
2.20e-20 |
|
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.
Pssm-ID: 433425 [Multi-domain] Cd Length: 88 Bit Score: 86.11 E-value: 2.20e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 27 LSGKVIDQH-GTPIAQATIAVENTTSGTYTDDRGKYSLQVAP-GKHTFVVSFLGYQTVKQSLDIRQD--KKQNFTLQESA 102
Cdd:pfam13715 1 ISGTVVDENtGEPLPGATVYVKGTTKGTVTDADGNFELKNLPaGTYTLVVSFVGYKTQEKKVTVSNDntLDVNFLLKEDA 80
|
....*...
gi 496329366 103 VALNSVEV 110
Cdd:pfam13715 81 LLLDEVVV 88
|
|
| TonB-hemin |
TIGR01785 |
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ... |
105-777 |
2.67e-20 |
|
TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273807 [Multi-domain] Cd Length: 665 Bit Score: 95.92 E-value: 2.67e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 105 LNSVEVYGKTQTQKVKEGAFAVNALDIKPIV-NSLNNLNDLVNRTTGIKVREeGGVGSDFDLSINGLSGNSIRYFLDGMP 183
Cdd:TIGR01785 1 LDTVTVTATRTRQVLSEAPASVSVISGEQIEsKQANNLADALNTVPGVDVTG-GGRPPGQSINIRGLQDNRVLVVVDGAR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 184 L--DTKGSGVSLANLPINIIDRIEIYKGVVPASLGTDALGGAINIITK------QEKKNY-LDVSYGIGSFhthktDLNT 254
Cdd:TIGR01785 80 QnyQRGGAHNGSLFVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKdaadllRPGQLFgGLAKLSYGSN-----NNSF 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 255 QFVEKGTGLIVRPTVG-INYSKNDyrMKNvqMRDESGDNFIYgnpkrfhDGY--FSLLAQVEagfvnkSWADAffvsasy 331
Cdd:TIGR01785 155 GGSVAVAGRLDDNLDAlVAATYRD--GGN--YRNGNKEEATN-------SAYvqKNLLAKLG------WQLDD------- 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 332 sktDKELQTGSVQNKVygmaernsdSWNI-SARYQKYNFILknmqlnaSLSHTWDHSLTVD-TAYRKYYW---DGGYI-- 404
Cdd:TIGR01785 211 ---AQRLEFSYFTTEG---------SLDEaQNSGPGTEYVL-------GSSSTLLASSTRDrSATLTYNWtpeDNPWLda 271
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 405 ---VSQRNEIMGKEPSMRHYKRPLTIMRTNLDYQLNTHHSFNLNYHLSRT-GNDRFDDLDT--SFEPSKDVvtkhilglS 478
Cdd:TIGR01785 272 tasLYYNRTENDNDRSARGVGREEGYQYTTYGATLQNTSRFDVASWSTLTyGVDWMKDKRRteSFDPNSVT--------T 343
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 479 YNQSLLDGK-MENVFFIKDYINHPNIRQT----------DQSSVTGSKDVQGSTTKNYLGYGAGLRYTIVEPLSIKVSYE 547
Cdd:TIGR01785 344 IVPNPPSAKeYFFGLFLQDNIPLLDDRLTlsaglrydhyKLSPKTTADTEAVDRSYSRWSPSLGLSYKPVDWLTLYASYS 423
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 548 HSVRLPIARELLGNGT--------TIYANVALKPENSNN----FNASLFGTWHpgNGHTFYYEMSGFFRKVNNYIQTSI- 614
Cdd:TIGR01785 424 QGFRAPSIDELYGTGDhpgtpggyTFAPNPNLKPETSKTwelgANLSFDNLLL--DNDQLQFKVAYFYNDVKDFIDLTIg 501
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 615 ------AEKEGTMQYTNVPAVHVKGVEGEIRYDWqGRLQLSTNVSYQDTRDQQKYKGDG-----KPSATYNNRVPNRPWL 683
Cdd:TIGR01785 502 vtdnvtAGMNNITQYVNIDGARIRGIEASASYDA-GLWATGLSYGYTIGKDQNTNQWLSnipplKLVVTVGYRFPDRRLD 580
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 684 FGSVEAYYtfrnialpESRLRLGCTYQWVHWYFLTWEAYGSYDNKAripaqhicnadiTYSWRRGRY---NLALEctNFL 760
Cdd:TIGR01785 581 LGAKAAYY--------ERQSESPTTEDVAANGLLTTPGYTVVDLYA------------TYQPNAVKGltvRFGVN--NLT 638
|
730
....*....|....*....
gi 496329366 761 DK--TAYDNYKLQKPGRAF 777
Cdd:TIGR01785 639 DRkyTPAQSVPGAGPGRNF 657
|
|
| TonB-hemlactrns |
TIGR01786 |
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ... |
139-726 |
1.39e-19 |
|
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273808 [Multi-domain] Cd Length: 715 Bit Score: 93.63 E-value: 1.39e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 139 NNLNDLVNRTTGIKVREEGGVGSDfDLSINGLSGNSIRYFLDGMPLDTKGSGVSLANLPINIID-----RIEIYKGVVPA 213
Cdd:TIGR01786 39 RNLRDLLRYEPGVSVVEGGRGGSQ-GINIRGLDKNRVAVLVDGIRQNTSYGGQGSTFYAINSIDpelikSIEIVKGASSS 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 214 SLGTDALGGAINIITKQ-------EKKNYLDVSYGIGSFHTHKTDLNTQFV--EKGTGLIvrptvgiNYSKNdyRMKNVQ 284
Cdd:TIGR01786 118 LYGSGALGGVVAFRTKDaadllkpGKDLGGLSKLGYSSANNRFTQSVAAAGrnDDVDALV-------QATYR--RGHELK 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 285 MRDESGDNFIYGNPKRFHDGY--FSLLAQVEAGFVNKSWADAFFVSASYSKTDKELQTGSVQNKVYGMAERNSdSWNISA 362
Cdd:TIGR01786 189 NGNKANIGNESKRSKPNPSDYksQSFLAKLGWQLNDAHRLGLSLEYTQTDYDEPEMTNTSYLTKPLGAPLLSS-TVVLGD 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 363 RYQKYNFILKNMQLNASLShtWdhsltVDTAYRKYYWDGGYIVSQRNEIMGKEPS------MRHYKRPLTI--MRTNLDY 434
Cdd:TIGR01786 268 SKTRDRRTGLDYELNPDNS--W-----LDTVKLALDKQYIQLYNYLNATSASDYPgvdkngRYKDKYDYYTlgFDTNNKI 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 435 QLNTH-HSFNL----NYHLSRTGNDRFDDLDT-----SFEPSKDVVTKHILGLSYNQSLLDGKMENVFF---IKDYINHP 501
Cdd:TIGR01786 341 EFSVHsLSLTYgldrFKDKVSTGDSRRNLPTAaynlyGYEGENRPVKGSNFGLFLQDNIKLGDWLSLSAglrYDHYKTDP 420
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 502 NIRQTDQSSVTgskdvqgSTTKNYLGYGAGLRYTIVEPLSIKVSYEHSVRLPIARELLGNGT-------TIYANVALKPE 574
Cdd:TIGR01786 421 KADESKDYGAI-------SKTYSRWSPSLGLTYKPTPWLTLYYSYSQGFRAPSFDELYGTGAhpgggpyTFLPNPNLKPE 493
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 575 NSNNFNASLfgtwhpgNGH--TFYYEMSGFFRKVNNYIQTSIAEKE----------GTMQYTNVPAVHVKGVEGEIRYD- 641
Cdd:TIGR01786 494 TSKNWEIGI-------NLHfdQLDFKVSYFRNDYKDFIDLGIGVTAkgnmaqvgsnTITNYVNIDNARIRGIELSGRYDl 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 642 ---WQGRLQLSTNVSY-------QDTRDQQKYKGDGKPSATYNNRVPNRPWlfgSVEAYYTF--RNIALPESRLRLGCTY 709
Cdd:TIGR01786 567 gsfFSGPDGWTTTLKYgytkgkdSDTNPWLNAITPLKVVLGLGYDHPDEKW---GVGLTLTFsgAKDAVDAYATYYENGE 643
|
650
....*....|....*..
gi 496329366 710 QwVHWYFLTWEAYGSYD 726
Cdd:TIGR01786 644 A-AKAGPLRTPSYTVVD 659
|
|
| TonB_dep_Rec |
pfam00593 |
TonB dependent receptor; This model now only covers the conserved part of the barrel structure. |
315-783 |
1.69e-19 |
|
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain] Cd Length: 475 Bit Score: 92.53 E-value: 1.69e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 315 GFVNKSWADAFFVSASYSKTDKELQTGSVQNKVYGMAERNSDSWNISARYQkynfilknmqLNASLSHTWDHSLTVDTAY 394
Cdd:pfam00593 18 GYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYD----------YDLGDGLSWLSTLRLGLRY 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 395 RKYYWDGGYIVSQRNEIMGKEPSMRHYKRPLTIMRTNLDYQLNTHHSFNLNYHLSRTGNDRFDDLDTSFEPSKDVVTKHI 474
Cdd:pfam00593 88 SSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPANPSSSSY 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 475 LGLSYNQSLLDGkMENVFFIKDYINHPNIRQTDQSSVTGSKDVQGSTTKNYLG---YGAGLRYTIVEPLSIKVSYEHSVR 551
Cdd:pfam00593 168 SDTTTDSYGLYL-QDNIKLTDRLTLTLGLRYDHYSTDGDDGNGGGDNFSRSYSafsPRLGLVYKPTDNLSLYASYSRGFR 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 552 LPIAREL------LGNGTTIYANVALKPENSNNFNASLfgTWHPGNghtFYYEMSGFFRKVNNYIQTS---IAEKEGTMQ 622
Cdd:pfam00593 247 APSLGELygsgsgGGGGAVAGGNPDLKPETSDNYELGL--KYDDGR---LSLSLALFYIDIKNLITSDpdgPGLGGTVYT 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 623 YTNVPAVHVKGVEGEIRYDWQGRLQLSTNVSYQDTRDQQKYKGDGkpsatynNRVPNRPWLFGSVEAYYTFRNIALpesR 702
Cdd:pfam00593 322 YTNVGKARIRGVELELSGRLWGLGLSGGGYTYTDADDDADADDTG-------NPLPNVPRHTANLGLTYDFPLGGW---G 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 703 LRLGCTYQWVhwyflTWEAYGSYDNKARIPAQHICNADITYSWRRgRYNLALECTNFLDKTAYDNYKLQK--------PG 774
Cdd:pfam00593 392 ARLGARYVGS-----GERRYGDAANTFKTPGYTLVDLSAGYRLNK-NLTLRLGVNNLFDKYYKRYYSSGGgnlggypgPG 465
|
....*....
gi 496329366 775 RAFFAKFRL 783
Cdd:pfam00593 466 RTFYLGLSY 474
|
|
| TonB-siderophor |
TIGR01783 |
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ... |
141-777 |
4.57e-17 |
|
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain] Cd Length: 651 Bit Score: 85.54 E-value: 4.57e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 141 LNDLVNRTTGIKVREEGGVGSDFDLSINGLSGNSIR--YFLDGMPLDtkgSGVSLANLPINIIDRIEIYKGvvPASL--G 216
Cdd:TIGR01783 22 LSEALQRVPGVVVGGSGGTTQFGNITIRGFGLEVDIdnVYLDGVPLL---SRGNLAIVDPAMVERVEVLRG--PASLlyG 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 217 TDALGGAINIITKQ---EKKNYLDVSYGIGSFHTHKTDLNTQFVEKGTgLIVRptvgINYSKNDYRmknvQMRDESGD-- 291
Cdd:TIGR01783 97 GSAPGGVINIVTKRpqdEPKGSVTFGAGTRSGYRTAFDLGGPLGADGT-FRGR----LNGARQDGD----SFYDGAGEet 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 292 NFIYGNPKRFHDGYFSLLAQVEAGfvnksWADAFFVSASYSKTDKELQTGSVQNKVYGmaerNSDSWNISARYQKYNFIL 371
Cdd:TIGR01783 168 RLGATATDWQLDDRTLLRLGAYYQ-----KERDRGGYGGLPASGGTSGRDLSSDRYLG----TSSNRNYDDREYLSYGLS 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 372 KNMQLNASLSHTWD--HSLTVDTAYRKYYW----DGGYIVSQRneiMGKEPSMRhykrpltimRTNLDYQLNTHHS-FNL 444
Cdd:TIGR01783 239 LEYQFNDVWTGKQNlrYSYFDTDSNQVQASgyssDGGLFGRSL---TVVNVKQD---------RVQIDAGLDGEFEtGPI 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 445 NYHLS---RTGNDRFDDLDTSFEPSKDV---VTKHILGLSYNQSLLDGKMENVFFIKDYINHPNIRQTDQSSVT------ 512
Cdd:TIGR01783 307 EHDLLlgvSYGQRTTNRFNNTGYPSDNIyslTATSSARTDIGDSPKDRALSSTTKALNGVALQRILLADKWTLTlggryd 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 513 --------GSKDVQGSTTKNYLGYGAGLRYTIVEPLSIKVSYEHSVRLPiareLLGNGTTIYANVALKPENSNNFNASLF 584
Cdd:TIGR01783 387 svdvksnnGVAGSTGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPG----GYYPKGAGNSGDILEPEKGKNYELGVR 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 585 GTWHPGNGHTFyyemsGFFR-KVNNYIQTSiaeKEGTMQYTNVPAVHVKGVEGEIRYDWQGRLQLSTNVSYQDTRDQqky 663
Cdd:TIGR01783 463 YDLGDSLLATA-----ALFRiTKDNQLVQD---PVNGTFSVNAGKTRNRGVELEARGYLTPGLSLSAGYTYTDAEFT--- 531
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 664 kgDGKPSATYNNRVPNRPWLFGSVEAYYTFRNIalpESRLRLGCTYQWVHwyfltwEAYGSYDNKARIPAQHICNADITY 743
Cdd:TIGR01783 532 --EDTNGDTQGNTVPFVPKHTASLWASYAPPVG---DNGLTLGGGVQYTG------KAYVDGGNTGKVPSYTVVDLSVRY 600
|
650 660 670 680
....*....|....*....|....*....|....*....|...
gi 496329366 744 -SWRRGRYNLALECTNFLDKTAY--------DNYKLQKPGRAF 777
Cdd:TIGR01783 601 dLTKKKNLTLALNVNNLFDRDYYtsgyrwgpSAYIYPGAPRTV 643
|
|
| Plug |
pfam07715 |
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ... |
118-223 |
6.09e-16 |
|
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Pssm-ID: 462243 [Multi-domain] Cd Length: 107 Bit Score: 74.23 E-value: 6.09e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 118 KVKEGAFAVNALDIKPIVNS-LNNLNDLVNRTTGIKVREEGGVGSDFdLSINGLSGNSIRYFLDGMPLDTKGSG-VSLAN 195
Cdd:pfam07715 1 DLRDTPGSVSVVTAEDIEDQgATNLADALRGVPGVSVSSGGGGGGSS-ISIRGFGSNRVLVLVDGVPLNSGGGGsVDLNS 79
|
90 100
....*....|....*....|....*...
gi 496329366 196 LPINIIDRIEIYKGVVPASLGTDALGGA 223
Cdd:pfam07715 80 IDPEDIERVEVLKGPASALYGSGAIGGV 107
|
|
| CarboxypepD_reg |
pfam13620 |
Carboxypeptidase regulatory-like domain; |
26-98 |
3.90e-14 |
|
Carboxypeptidase regulatory-like domain;
Pssm-ID: 433354 [Multi-domain] Cd Length: 81 Bit Score: 68.08 E-value: 3.90e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 26 TLSGKVIDQHGTPIAQATIAVEN----TTSGTYTDDRGKYSL-QVAPGKHTFVVSFLGYQTVKQS---LDIRQDKKQNFT 97
Cdd:pfam13620 1 TISGTVTDPSGAPVPGATVTVTNtdtgTVRTTTTDADGRYRFpGLPPGTYTVTVSAPGFKTATRTgvtVTAGQTTTLDVT 80
|
.
gi 496329366 98 L 98
Cdd:pfam13620 81 L 81
|
|
| PRK13484 |
PRK13484 |
IreA family TonB-dependent siderophore receptor; |
60-669 |
5.29e-13 |
|
IreA family TonB-dependent siderophore receptor;
Pssm-ID: 139605 [Multi-domain] Cd Length: 682 Bit Score: 72.73 E-value: 5.29e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 60 KYSLQVAPGKHTFVVSFL--GYQTVKQSLDIRQDKKQNFTlQESAVALNSVEVYGKTQTQKvkegafavnaldiKPIvns 137
Cdd:PRK13484 2 KNKYIIAPGIAVMCSAVIssGYASSDKKEDTLVVTASGFT-QQLRNAPASVSVITSEQLQK-------------KPV--- 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 138 lNNLNDLVNRTTGIKVReegGVGSDFDLSINGLSGNSIRYFLDGMPLDTK-----GSGVSLANL--PINIIDRIEIYKGV 210
Cdd:PRK13484 65 -SDLVDAVKDVEGISIT---GGNEKPDISIRGLSGDYTLILVDGRRQSGResrpnGSGGFEAGFipPVEAIERIEVIRGP 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 211 VPASLGTDALGGAINIITKQEKKNYLDVSYGIGSFHTHKTDLNtqfvekgtglivrptvgiNYSKNDYRMKNVQMRDESG 290
Cdd:PRK13484 141 MSSLYGSDAIGGVINIITKPVNNQTWDGVLGLGGIIQEHGKFG------------------NSTTNDFYLSGPLIKDKLG 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 291 DNfIYGnpkrfhdgyfsllaqveagfvnkswadaffvSASYSKTDKELQ-TGSVQNKvygmaernsdswNISARYQ---- 365
Cdd:PRK13484 203 LQ-LYG-------------------------------GMNYRKEDSISQgTPAKDNK------------NITATLQftpt 238
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 366 -KYNFIL---KNMQLnaslshtwdHSLTVDTAYRKYYWDGGYIvsQRNEIMGKEPSMRH----YKRPLTIMRTNLD-YQL 436
Cdd:PRK13484 239 eSQKFVFeygKNNQV---------HTLTPGESLDAWTMRGNLK--QPNSKRETHNSRSHwvaaWNAQGEILHPEIAvYQE 307
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 437 NTHHSfnlnyhLSRTGNDRFDDLDTSFEPSKDVVTKHILGLSYNQSLLDgkmeNVFFIKDYINHPNIRqtDQSSvTGSKD 516
Cdd:PRK13484 308 KVIRE------VKSGKKDKYNHWDLNYESRKPEITNTIIDAKVTAFLPE----NVLTIGGQFQHAELR--DDSA-TGKKT 374
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 517 VQGST---------------TKNYLGYGAGLR------------------YTIVEPLSIKVSYEHSVRLPIARELL-GNG 562
Cdd:PRK13484 375 TETQSvsikqkavfieneyaATDSLALTGGLRldnheiygsywnprlyavYNLTDNLTLKGGIAKAFRAPSIREVSpGFG 454
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 563 TT-------IYANVALKPE------------NSNNF--NASLFGTwhpgnghtfyyemsGFFRKVNNYIQTSIAEKEG-- 619
Cdd:PRK13484 455 TLtqggasiMYGNRDLKPEtsvteeigiiysNDSGFsaSATLFNT--------------DFKNKLTSYDIGTKDPVTGln 520
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*.
gi 496329366 620 TMQYTNVPAVHVKGVEGEIRYDWQGRLQLSTNVSYQDTR---DQQKYKGD---GKP 669
Cdd:PRK13484 521 TFIYDNVGEANIRGVELATQIPVYDKWHVSANYTFTDSRrksDDESLNGKslkGEP 576
|
|
| btuB |
PRK10641 |
TonB-dependent vitamin B12 receptor BtuB; |
139-385 |
1.10e-12 |
|
TonB-dependent vitamin B12 receptor BtuB;
Pssm-ID: 236730 [Multi-domain] Cd Length: 614 Bit Score: 71.56 E-value: 1.10e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 139 NNLNDLVNRTTGIKVREEGGVGSDFDLSINGLSGNSIRYFLDGMPLDTKG-SGVS-LANLPINIIDRIEIYKGVVPASLG 216
Cdd:PRK10641 60 KSVNDVLRRLPGVDIAQNGGLGQLSSLFIRGTNSSHVLVLIDGVRLNQAGiSGSAdLSQIPISLVQRIEYIRGPRSAVYG 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 217 TDALGGAINIITKQEKKNyLDVSYGIGSFHTHKTDLNTQfveKGTGLIVRPTVGINYSknDYRMKNVQMRDESGDnfiYG 296
Cdd:PRK10641 140 SDAIGGVVNIITTRDKPG-TTLSAGWGSNGYQNYDGSTQ---QQLGDNTRVTLAGDYT--YTKGFDVVAYGNTGT---QA 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 297 NPKRfhDGYFS--LLAQVE-------AGFV------NKSWADAFFVSASYSkTDkelqtgsvQNKVYgmaernSDSWNIS 361
Cdd:PRK10641 211 QPDR--DGFMSktLWGGLEhqfndqwSGFVrgygydNRTDYDAYYSPGSPL-ID--------TRQLY------SQSWDAG 273
|
250 260
....*....|....*....|....
gi 496329366 362 ARYQKYNFilkNMQLNASLSHTWD 385
Cdd:PRK10641 274 LRYNGGIY---SSQLIASYSHSKD 294
|
|
| PRK10064 |
PRK10064 |
catecholate siderophore receptor CirA; Provisional |
129-669 |
9.44e-11 |
|
catecholate siderophore receptor CirA; Provisional
Pssm-ID: 236646 [Multi-domain] Cd Length: 663 Bit Score: 65.29 E-value: 9.44e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 129 LDIKPIvnslNNLNDLVNRTTGIKVREEGGvgSDFDLSINGLSGNSIRYFLDGMPLDT-----KGSGVSLANLPINIIDR 203
Cdd:PRK10064 59 LQRKPV----QNLKDVLKEVPGVQLTNEGD--NRKGVSIRGLDSSYTLILIDGKRVNSrnavfRHNDFDLNWIPVDAIER 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 204 IEIYKGVVPASLGTDALGGAINIITKQEKKNY---LDVSYGIGSFHTHKTDLNTQFVEKGTglIVRPTVGIN-YSKNDYR 279
Cdd:PRK10064 133 IEVVRGPMSSLYGSDALGGVVNIITKKIGQKWhgtVTVDTTIQEHRDRGDTYNGQFFTSGP--LIDGVLGMKaYGSLAKR 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 280 MKNVQMRDESGDNfiyGNPKRFhDGYFSLLAQVEAgfvnkSWA--DAFFVSASYSktdkelqtgsvqnkvYGMAERNSDS 357
Cdd:PRK10064 211 EKDDPQNSTTTDT---GETPRI-EGFTSRDGNVEF-----AWTpnQNHDFTAGYG---------------FDRQDRDSDS 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 358 WNISaryqkynfilKNMQLNASLSHT--WDhsltVDTAYRKYYWD---------GGYIVSQRNEIMGKepsmrhYKRPLT 426
Cdd:PRK10064 267 LDKN----------RLERQNYSLSHNgrWD----YGNSELKYYGEkvenknpgnSSPITSESNSIDGK------YTLPLT 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 427 imrtnldyqlnthhsfNLNYHLSRTGNDRFDDLdtsfepsKDVVTkhilgLSYNQSLLDGKMENVFFIKDYInhpNIRQt 506
Cdd:PRK10064 327 ----------------AINQFLTFGGEWRHDKL-------SDAVN-----LTGGTSSKTSASQYALFVEDEW---RIFE- 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 507 DQSSVTGSKDVQGSTTKNYLGYGAGLRYTIVEPLSIKVSYEHSVRLPIARELLGNGTT--------IYANVALKPENSNN 578
Cdd:PRK10064 375 PLALTTGVRMDDHETYGDHWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQLSPDWTSnscrgackIVGSPDLKPETSES 454
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 579 FNASLFGTWHPGNGHTFYYEMSGFFRKVNNYIQTSI---------------------AEKEGTMQYTNVPAVHVKGVEGE 637
Cdd:PRK10064 455 WELGLYYMGEEGWLEGVESSVTVFRNDVDDRISISRtsdvnaapgyqnfvgfetngrGRRVPVFRYYNVNKARIQGVETE 534
|
570 580 590
....*....|....*....|....*....|..
gi 496329366 638 IRYDWQGRLQLSTNVSYQDTRDQQkyKGDGKP 669
Cdd:PRK10064 535 LKIPFNDEWKLSLNYTYNDGRDVS--NGENKP 564
|
|
| PRK13513 |
PRK13513 |
ligand-gated channel protein; |
158-459 |
5.89e-09 |
|
ligand-gated channel protein;
Pssm-ID: 184104 [Multi-domain] Cd Length: 659 Bit Score: 59.40 E-value: 5.89e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 158 GVGSDFDLSINGLSGNSIRYFLDGMPLDTK-------GSGVSLANLP-INIIDRIEIYKGVVPASLGTDALGGAINIITK 229
Cdd:PRK13513 86 GGGSTSDISIRGMAAKYTLILVDGKRVDTRstrpnsdGSGIEQGWLPpLAAIERIEVVRGPMSSLYGSDAMGGVINIITR 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 230 QEKKNYldvsygIGSFHthktdLNTQFVEkgtglivRPTVGINYSKNDYrmknvqmrdESG---DNF----IYG-----N 297
Cdd:PRK13513 166 KVQKEW------HGSLR-----ADATLQE-------DSKSGDIFQTNAY---------ASGpliDGLlglkVSGllshrS 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 298 PKRFHDGYFSllAQVEAGFVNKSWA----DAFFVSASYSKTDKELQTGsvqnkvYGMAERNSDSWNisaRYQKYNFilkn 373
Cdd:PRK13513 219 EDKIIDGYNE--QRMRNGTATFSLTpddnNEFDFEIGRYVQDRNSTPG------RTLALNGTNSDT---QYDRNNY---- 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 374 mqlnaSLSHTWdhsltvdtayrkyYWDGGYIVS--QRNEIMGKEPSMRHYkrpltimrtnlDYQLNTHHSFNLNYH-LSR 450
Cdd:PRK13513 284 -----AITHNG-------------YYDFGNSTSyiQRDETRNPSRQMKSV-----------DTIFNTQTSFLLDDHtLSL 334
|
....*....
gi 496329366 451 TGNDRFDDL 459
Cdd:PRK13513 335 GGQYRYEEL 343
|
|
| PRK13486 |
PRK13486 |
TonB-dependent receptor; |
96-668 |
6.27e-08 |
|
TonB-dependent receptor;
Pssm-ID: 139606 [Multi-domain] Cd Length: 696 Bit Score: 56.18 E-value: 6.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 96 FTLQESAVALNSVEVYGKTQTQKVKEGAFAVNALDIKPI-VNSLNNLNDLVNRTTGIKVREEGGVGSDFDLSINGLSGNS 174
Cdd:PRK13486 16 FSASSIAAAEDVMIVSASGYEKKLTNAAASVSVISQEELqSSQYHDLAEALRSVEGVDVESGTGKTGGLEISIRGMPASY 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 175 IRYFLDGM----PLDTKGSGVSLANL----PINIIDRIEIYKGVVPASLGTDALGGAINIITKQE-KKNYLDVSYGIGSF 245
Cdd:PRK13486 96 TLILIDGVrqggSSDVTPNGFSAMNTgfmpPLAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKNaDKWLSSVNAGLNLQ 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 246 HTHKTDLNTQFVEKGTGLIVRPTVGINYSKNDYRMKN---VQMRDESGDNFIYgnPKRFHDgyFSLLAQVE--AGFVNKS 320
Cdd:PRK13486 176 ESNKWGNSSQFNFWSSGPLVDDSVSLQVRGSTQQRQGssvTSLSDTAATRIPY--PTESQN--YNLGARLDwkASEQDVL 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 321 WADAFFVSASYSKTDKELqtGSVqnkvygmaernSDSWNISARYQKynfilknmqlnASLSHTWDHSLTVDTAYRKYYWD 400
Cdd:PRK13486 252 WFDMDTTRQRYDNRDGQL--GSL-----------TGGYDRTLRYER-----------NKISAGYDHTFTFGTWKSYLNWN 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 401 -----GGYIVSQ--RNEIMGKEPSMRHYKRPLTIMRTNLDYQLNTHHSFNL--NYHLSRTgndrfddldtsfepsKDVVT 471
Cdd:PRK13486 308 etenkGRELVRSvlKRDKWGLAGQPRELKESNLILNSLLLTPLGESHLVTVggEFQSSSM---------------KDGVV 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 472 KHILGLSYNQSLLDGKMENVFFIKDYInhpnirqtdqSSVTGSKDVQGSTTKNYLGYGAGLRYTIVEPLSIKVSYEHSVR 551
Cdd:PRK13486 373 LASTGETFRQKSWSVFAEDEWHLTDAL----------ALTAGSRYEHHEQFGGHFSPRAYLVWDVADAWTLKGGVTTGYK 442
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 552 LPIAREL-------LGNGTT-IYANVALKPENSNNFNASLFGTwhpgNGHTFYYEMSGFFRKVNNYIqTSIAEKEGTMQY 623
Cdd:PRK13486 443 APRMGQLhkgisgvSGQGKTnLLGNPDLKPEESVSYEAGVYYD----NPAGLNANVTGFMTDFSNKI-VSYSINDNTNSY 517
|
570 580 590 600
....*....|....*....|....*....|....*....|....*.
gi 496329366 624 TNVPAVHVKGVEGEIRYD-WQGRLQLSTNVSYqdTRDQQKyKGDGK 668
Cdd:PRK13486 518 VNSGKARLHGVEFAGTLPlWSEDVTLSLNYTW--TRSEQR-DGDNK 560
|
|
| Peptidase_M14NE-CP-C_like |
cd11308 |
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, ... |
29-98 |
1.08e-06 |
|
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; This domain is found C-terminal to the M14 carboxypeptidase (CP) N/E subfamily containing zinc-binding enzymes that hydrolyze single C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. The N/E subfamily includes enzymatically active members (carboxypeptidase N, E, M, D, and Z), as well as non-active members (carboxypeptidase-like protein 1, -2, aortic CP-like protein, and adipocyte enhancer binding protein-1) which lack the critical active site and substrate-binding residues considered necessary for activity. The active N/E enzymes fulfill a variety of cellular functions, including prohormone processing, regulation of peptide hormone activity, alteration of protein-protein or protein-cell interactions and transcriptional regulation. For M14 CPs, it has been suggested that this domain may assist in folding of the CP domain, regulate enzyme activity, or be involved in interactions with other proteins or with membranes; for carboxypeptidase M, it may interact with the bradykinin 1 receptor at the cell surface. This domain may also be found in other peptidase families.
Pssm-ID: 200604 [Multi-domain] Cd Length: 76 Bit Score: 46.75 E-value: 1.08e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 496329366 29 GKVIDQHGTPIAQATIAVENTTSGTYTDDRGKYSLQVAPGKHTFVVSFLGYQTVKQSLDIRQDKK---QNFTL 98
Cdd:cd11308 4 GFVTDATGNPIANATISVEGINHDVTTAKDGDYWRLLLPGTYNVTASAPGYQPVTKTVTVPNNFSatvVNFTL 76
|
|
| PRK13483 |
PRK13483 |
ligand-gated channel protein; |
94-230 |
2.79e-06 |
|
ligand-gated channel protein;
Pssm-ID: 184080 [Multi-domain] Cd Length: 660 Bit Score: 50.93 E-value: 2.79e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 94 QNFTLQESAVALNSVEVYGKTQTQKVKEGAFAVNALDIKPIVN-SLNNLNDLVNRTTGIKVreEGGvGSDFDLSINGLSG 172
Cdd:PRK13483 22 HALAQAAPDKTMETVVVTASGYEQQIRDAPASISVITREDLENrFYRDLTDALLDVPGVVV--TGG-GDRTDISLRGMGS 98
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 496329366 173 NSIRYFLDGMPLDTK-------GSGVSLANLP-INIIDRIEIYKGVVPASLGTDALGGAINIITKQ 230
Cdd:PRK13483 99 QYTLILVDGKRQSSRetrpnsdGPGVEQAWTPpLAAIERIEVIRGPMSSLYGSDAIGGVINIITRK 164
|
|
| PRK13528 |
PRK13528 |
outer membrane receptor FepA; Provisional |
114-230 |
9.30e-05 |
|
outer membrane receptor FepA; Provisional
Pssm-ID: 237413 [Multi-domain] Cd Length: 727 Bit Score: 45.90 E-value: 9.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 114 TQTQKVKE--GAFAVNALDIK--PIVNslnNLNDLVNRTTGIKV---REEGGVGSDFDLSINGL---------------S 171
Cdd:PRK13528 42 TAEQELKQqpGVSIITAEDIKkrPPVN---DLSDIIRKMPGVNLtgnSASGTRGNNRQIDIRGMgpentlilidgvpvtS 118
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 496329366 172 GNSIRYFLDGmPLDTKGSgvslAN-LPINIIDRIEIYKGVVPASLGTDALGGAINIITKQ 230
Cdd:PRK13528 119 RNSVRYSWRG-ERDTRGD----TNwVPPEMVERIEVIRGPAAARYGSGAAGGVVNIITKR 173
|
|
| PRK13524 |
PRK13524 |
FepA family TonB-dependent siderophore receptor; |
171-230 |
1.18e-03 |
|
FepA family TonB-dependent siderophore receptor;
Pssm-ID: 237410 [Multi-domain] Cd Length: 744 Bit Score: 42.32 E-value: 1.18e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 496329366 171 SGNSIRYFLDGmPLDTKGSgvslAN-LPINIIDRIEIYKGVVPASLGTDALGGAINIITKQ 230
Cdd:PRK13524 120 SRNSVRYGWRG-ERDTRGD----TNwVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKK 175
|
|
| |
