|
Name |
Accession |
Description |
Interval |
E-value |
| PRK03818 |
PRK03818 |
putative transporter; Validated |
1-552 |
0e+00 |
|
putative transporter; Validated
Pssm-ID: 179654 [Multi-domain] Cd Length: 552 Bit Score: 955.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 1 MSEIALTVSVLALVAVVGLWIGNVKIRGVGFGIGGVLFGGIIVGHFVDQAGVALSSPMLHFIQEFGLILFVYTIGIQVGP 80
Cdd:PRK03818 1 MSDIALTVSILALVAVVGLWIGNIKIRGVGLGIGGVLFGGIIVGHFVSQFGLTLDSDMLHFIQEFGLILFVYTIGIQVGP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 81 GFFASLRVSGLRLNLFAILIVILGGLVTAVLHKLFNIPLPVVLGIFSGAVTNTPALGAGQQILRDLGVPFEVVDQMGMSY 160
Cdd:PRK03818 81 GFFSSLRKSGLRLNLFAVLIVILGGLVTAILHKLFGIPLPVMLGIFSGAVTNTPALGAGQQILRDLGTPGDLVDQMGMGY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 161 AMAYPFGICGILLTMWLVRLFFRINVEKEAQRFEESSGNGHANLHTINVRVENPNLNQMAIQDVPMLNSDNIVCSRLKRG 240
Cdd:PRK03818 161 AMAYPFGICGILLSMWLIRLIFRINVDKEAQEFESSSGNGHELLQTINIRVENPNLHGKAIKDVPILNGDKFVCSRLKRG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 241 ELLMVPAPGTLIQAGDLLHLVGRPEDLHNAQLVIGQEVATSLSTRGTDLKVERVVVTNEKVLGKKIRDLHVKQRYDVVIS 320
Cdd:PRK03818 241 DTLMVPSPDTIIQLGDLLHLVGQPEDLHKAQLVIGEEVDTSLSTRGTDLRSERVVVTNEKVLGKKLRDLHLKNKYGVVIS 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 321 RLNRAGVELVASSSASLQFGDILNLVGRQEAIDAVAAELGNAQQKLQQVQMLPVFIGIGLGVLLGSIPLFIPGFPAALKL 400
Cdd:PRK03818 321 RLNRAGVELVASPDLSLQFGDILNLVGRPEAIDAVANVLGNAQQKLQQVQMLPVFIGIGLGVLLGSIPFFIPGFPAALKL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 401 GLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLAVVGLKSGGDFVATLTQGEGLSWIAYGIFITAIPLLT 480
Cdd:PRK03818 401 GLAGGPLIVALILGRIGSIGKLYWFMPPSANLALRELGIVLFLAVVGLKSGGDFVDTLVNGEGLSWIGYGFLITAVPLLI 480
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 496082244 481 VGILARMLAKMNYLTLCGMLAGSMTDPPALAFANNLHATSGAAALSYATVYPLVMFLRIITPQLLAVLFWGL 552
Cdd:PRK03818 481 VGILARMLAKMNYLTLCGMLAGSMTDPPALAFANNLHPTSGAAALSYATVYPLVMFLRIITPQLLAVLFWSL 552
|
|
| YbjL |
COG2985 |
Uncharacterized membrane protein YbjL, putative transporter [General function prediction only]; ... |
18-549 |
0e+00 |
|
Uncharacterized membrane protein YbjL, putative transporter [General function prediction only];
Pssm-ID: 442224 [Multi-domain] Cd Length: 543 Bit Score: 662.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 18 GLWIGNVKIRGVGFGIGGVLFGGIIVGHFvdqagvALSSPMLHFIQEFGLILFVYTIGIQVGPGFFASLRVSGLRLNLFA 97
Cdd:COG2985 22 GYLLGKIKIGGFSLGVAGVLFVGLLIGHF------GVTLHIPHFVKSLGLALFVYAIGLQVGPGFFASLKRDGLKLNLLA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 98 ILIVILGGLVTAVLHKLFNIPLPVVLGIFSGAVTNTPALGAGQQILRDLGVPFEVVDQMGMSYAMAYPFGICGILLTMWL 177
Cdd:COG2985 96 VVVVVLGLLVALALAKLFGLDPGLAAGLFAGALTNTPALGAAQDALGKLGLSKQLSANPAVGYAVAYPFGVIGIILFVAL 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 178 VRLFFRINVEKEAQRFEESSGNGHANLHTINVRVENPNLNQMAIQDVPMLNSDNIVCSRLKRGELLMVPAPGTLIQAGDL 257
Cdd:COG2985 176 LPKLFRIDLDAEAKKLEAGEGSAYPPLVTRAYRVTNPNLVGKTVAELEALLGTRVVISRIRRGGEIIVPTPDTVLQEGDI 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 258 LHLVGRPEDLHNAQLVIGQEVATSlSTRGTDLKVERVVVTNEKVLGKKIRDLHVKQRYDVVISRLNRAGVELVASSSASL 337
Cdd:COG2985 256 VLVVGTREALEAAEALLGEEVDDS-ELLDSDLDVRRIVVTNKEVAGKTLGELNLRNRFGVVITRVRRGGVELPATPDTVL 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 338 QFGDILNLVGRQEAIDAVAAELGNAQQKLQQVQMLPVFIGIGLGVLLGSIPLFIPGFPaALKLGLAGGPLIMALILGRIG 417
Cdd:COG2985 335 QLGDRLTVVGPKEDVERVAKLLGNSERKLSETDLLPLGLGIVLGLLLGSIPIPLPGIP-PLSLGLAGGPLIVGLLLGRLG 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 418 SIGKLYWFMPPSANLALRELGIVLFLAVVGLKSGGDFVATLTQgEGLSWIAYGIFITAIPLLTVGILARMLAKMNYLTLC 497
Cdd:COG2985 414 RTGPLVGYMPPSANLLLRELGLALFLAVVGLSAGPGFVETLQE-SGLLLFLLGALVTLVPLLVVLLVGRYVLKLNYLILL 492
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|..
gi 496082244 498 GMLAGSMTDPPALAFANNLHAtSGAAALSYATVYPLVMFLRIITPQLLAVLF 549
Cdd:COG2985 493 GALAGAMTSPPALAAANEAAG-SDAPALGYATVYPLAMILLILLGQLLVLLL 543
|
|
| YidE_YbjL_dupl |
TIGR01625 |
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is ... |
378-533 |
5.60e-49 |
|
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is duplicated the aspartate-alanine antiporter AspT, as well as HI0035 of Haemophilus influenzae, YidE and YbjL of E. coli, and a number of other known or putative transporters. Member proteins may have 0, 1, or 2 copies of TrkA potassium uptake domain pfam02080 between the duplications. The domain contains several apparent transmembrane regions and is proposed here to act in transport. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 130686 [Multi-domain] Cd Length: 154 Bit Score: 166.35 E-value: 5.60e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 378 IGLGVLLGSIPLFIPGFPaaLKLGLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLAVVGLKSGGDFVAT 457
Cdd:TIGR01625 1 LALGLLLGKIPIGLPGFS--IKLGNAGGVLFVGLLLGHFGATGPLTWYIPFSANLFIREFGLMLFLYGVGLSAGPGFFSS 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 496082244 458 LTQGEGLSWIAYGIFITAIPLLTVGILARMLAKMNYLTLCGMLAGSMTDPPALAFANNLHATSGAAALSYATVYPL 533
Cdd:TIGR01625 79 LKDGGGLLRINGGALITVVPTLLVAVALIKLLRINYALTAGMLAGATTNTPALDAANDTLRTSDLPALGYATVYPL 154
|
|
| Asp-Al_Ex |
pfam06826 |
Predicted Permease Membrane Region; This family represents five transmembrane helices that are ... |
373-546 |
1.66e-45 |
|
Predicted Permease Membrane Region; This family represents five transmembrane helices that are normally found flanking (five either side) a pair of pfam02080 domains. This suggests that the paired regions form a ten helical structure, probably forming the pore, whereas the pfam02080) binds a ligand for export or regulation of the pore. Swiss:Q8L3K8 is described as a aspartate-alanine antiporter. In conjunction with Swiss:Q8L3K9 it forms a 'proton motive metabolic cycle catalyzed by an aspartate-alanine exchange'. The general conservation of domain architecture in this family suggests that they are functional orthologues.
Pssm-ID: 284291 [Multi-domain] Cd Length: 167 Bit Score: 157.73 E-value: 1.66e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 373 PVFIGIGLGVLLGSIPlfipgFPAALKLGLAGGPLIMALILGRIGSIGKLywFMPPSANLALRELGIVLFLAVVGLKSGG 452
Cdd:pfam06826 1 ALFLGIALGLLLGRIK-----ISGGFSLGVAGGVLIVGLLLGHFGSTGPT--FMPISALSFLRELGLALFLAAVGLSAGP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 453 DFVATLTQGeGLSWIAYGIFITAIPLLTVGILARMLAKMNYLTLCGMLAGSMTDPPALAFANNLHATSGAAALSYATVYP 532
Cdd:pfam06826 74 GFFSSLKKD-GLLLIGLALLVTVVPLLLALVLGKYVLKLDPGLLAGLLAGALTSTPALGAANDALAGSDIPALGYAVTYP 152
|
170
....*....|....
gi 496082244 533 LVMFLRIITPQLLA 546
Cdd:pfam06826 153 FGVVGLILAGQVLA 166
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK03818 |
PRK03818 |
putative transporter; Validated |
1-552 |
0e+00 |
|
putative transporter; Validated
Pssm-ID: 179654 [Multi-domain] Cd Length: 552 Bit Score: 955.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 1 MSEIALTVSVLALVAVVGLWIGNVKIRGVGFGIGGVLFGGIIVGHFVDQAGVALSSPMLHFIQEFGLILFVYTIGIQVGP 80
Cdd:PRK03818 1 MSDIALTVSILALVAVVGLWIGNIKIRGVGLGIGGVLFGGIIVGHFVSQFGLTLDSDMLHFIQEFGLILFVYTIGIQVGP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 81 GFFASLRVSGLRLNLFAILIVILGGLVTAVLHKLFNIPLPVVLGIFSGAVTNTPALGAGQQILRDLGVPFEVVDQMGMSY 160
Cdd:PRK03818 81 GFFSSLRKSGLRLNLFAVLIVILGGLVTAILHKLFGIPLPVMLGIFSGAVTNTPALGAGQQILRDLGTPGDLVDQMGMGY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 161 AMAYPFGICGILLTMWLVRLFFRINVEKEAQRFEESSGNGHANLHTINVRVENPNLNQMAIQDVPMLNSDNIVCSRLKRG 240
Cdd:PRK03818 161 AMAYPFGICGILLSMWLIRLIFRINVDKEAQEFESSSGNGHELLQTINIRVENPNLHGKAIKDVPILNGDKFVCSRLKRG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 241 ELLMVPAPGTLIQAGDLLHLVGRPEDLHNAQLVIGQEVATSLSTRGTDLKVERVVVTNEKVLGKKIRDLHVKQRYDVVIS 320
Cdd:PRK03818 241 DTLMVPSPDTIIQLGDLLHLVGQPEDLHKAQLVIGEEVDTSLSTRGTDLRSERVVVTNEKVLGKKLRDLHLKNKYGVVIS 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 321 RLNRAGVELVASSSASLQFGDILNLVGRQEAIDAVAAELGNAQQKLQQVQMLPVFIGIGLGVLLGSIPLFIPGFPAALKL 400
Cdd:PRK03818 321 RLNRAGVELVASPDLSLQFGDILNLVGRPEAIDAVANVLGNAQQKLQQVQMLPVFIGIGLGVLLGSIPFFIPGFPAALKL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 401 GLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLAVVGLKSGGDFVATLTQGEGLSWIAYGIFITAIPLLT 480
Cdd:PRK03818 401 GLAGGPLIVALILGRIGSIGKLYWFMPPSANLALRELGIVLFLAVVGLKSGGDFVDTLVNGEGLSWIGYGFLITAVPLLI 480
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 496082244 481 VGILARMLAKMNYLTLCGMLAGSMTDPPALAFANNLHATSGAAALSYATVYPLVMFLRIITPQLLAVLFWGL 552
Cdd:PRK03818 481 VGILARMLAKMNYLTLCGMLAGSMTDPPALAFANNLHPTSGAAALSYATVYPLVMFLRIITPQLLAVLFWSL 552
|
|
| YbjL |
COG2985 |
Uncharacterized membrane protein YbjL, putative transporter [General function prediction only]; ... |
18-549 |
0e+00 |
|
Uncharacterized membrane protein YbjL, putative transporter [General function prediction only];
Pssm-ID: 442224 [Multi-domain] Cd Length: 543 Bit Score: 662.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 18 GLWIGNVKIRGVGFGIGGVLFGGIIVGHFvdqagvALSSPMLHFIQEFGLILFVYTIGIQVGPGFFASLRVSGLRLNLFA 97
Cdd:COG2985 22 GYLLGKIKIGGFSLGVAGVLFVGLLIGHF------GVTLHIPHFVKSLGLALFVYAIGLQVGPGFFASLKRDGLKLNLLA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 98 ILIVILGGLVTAVLHKLFNIPLPVVLGIFSGAVTNTPALGAGQQILRDLGVPFEVVDQMGMSYAMAYPFGICGILLTMWL 177
Cdd:COG2985 96 VVVVVLGLLVALALAKLFGLDPGLAAGLFAGALTNTPALGAAQDALGKLGLSKQLSANPAVGYAVAYPFGVIGIILFVAL 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 178 VRLFFRINVEKEAQRFEESSGNGHANLHTINVRVENPNLNQMAIQDVPMLNSDNIVCSRLKRGELLMVPAPGTLIQAGDL 257
Cdd:COG2985 176 LPKLFRIDLDAEAKKLEAGEGSAYPPLVTRAYRVTNPNLVGKTVAELEALLGTRVVISRIRRGGEIIVPTPDTVLQEGDI 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 258 LHLVGRPEDLHNAQLVIGQEVATSlSTRGTDLKVERVVVTNEKVLGKKIRDLHVKQRYDVVISRLNRAGVELVASSSASL 337
Cdd:COG2985 256 VLVVGTREALEAAEALLGEEVDDS-ELLDSDLDVRRIVVTNKEVAGKTLGELNLRNRFGVVITRVRRGGVELPATPDTVL 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 338 QFGDILNLVGRQEAIDAVAAELGNAQQKLQQVQMLPVFIGIGLGVLLGSIPLFIPGFPaALKLGLAGGPLIMALILGRIG 417
Cdd:COG2985 335 QLGDRLTVVGPKEDVERVAKLLGNSERKLSETDLLPLGLGIVLGLLLGSIPIPLPGIP-PLSLGLAGGPLIVGLLLGRLG 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 418 SIGKLYWFMPPSANLALRELGIVLFLAVVGLKSGGDFVATLTQgEGLSWIAYGIFITAIPLLTVGILARMLAKMNYLTLC 497
Cdd:COG2985 414 RTGPLVGYMPPSANLLLRELGLALFLAVVGLSAGPGFVETLQE-SGLLLFLLGALVTLVPLLVVLLVGRYVLKLNYLILL 492
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|..
gi 496082244 498 GMLAGSMTDPPALAFANNLHAtSGAAALSYATVYPLVMFLRIITPQLLAVLF 549
Cdd:COG2985 493 GALAGAMTSPPALAAANEAAG-SDAPALGYATVYPLAMILLILLGQLLVLLL 543
|
|
| YidE_YbjL_dupl |
TIGR01625 |
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is ... |
378-533 |
5.60e-49 |
|
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is duplicated the aspartate-alanine antiporter AspT, as well as HI0035 of Haemophilus influenzae, YidE and YbjL of E. coli, and a number of other known or putative transporters. Member proteins may have 0, 1, or 2 copies of TrkA potassium uptake domain pfam02080 between the duplications. The domain contains several apparent transmembrane regions and is proposed here to act in transport. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 130686 [Multi-domain] Cd Length: 154 Bit Score: 166.35 E-value: 5.60e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 378 IGLGVLLGSIPLFIPGFPaaLKLGLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLAVVGLKSGGDFVAT 457
Cdd:TIGR01625 1 LALGLLLGKIPIGLPGFS--IKLGNAGGVLFVGLLLGHFGATGPLTWYIPFSANLFIREFGLMLFLYGVGLSAGPGFFSS 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 496082244 458 LTQGEGLSWIAYGIFITAIPLLTVGILARMLAKMNYLTLCGMLAGSMTDPPALAFANNLHATSGAAALSYATVYPL 533
Cdd:TIGR01625 79 LKDGGGLLRINGGALITVVPTLLVAVALIKLLRINYALTAGMLAGATTNTPALDAANDTLRTSDLPALGYATVYPL 154
|
|
| Asp-Al_Ex |
pfam06826 |
Predicted Permease Membrane Region; This family represents five transmembrane helices that are ... |
373-546 |
1.66e-45 |
|
Predicted Permease Membrane Region; This family represents five transmembrane helices that are normally found flanking (five either side) a pair of pfam02080 domains. This suggests that the paired regions form a ten helical structure, probably forming the pore, whereas the pfam02080) binds a ligand for export or regulation of the pore. Swiss:Q8L3K8 is described as a aspartate-alanine antiporter. In conjunction with Swiss:Q8L3K9 it forms a 'proton motive metabolic cycle catalyzed by an aspartate-alanine exchange'. The general conservation of domain architecture in this family suggests that they are functional orthologues.
Pssm-ID: 284291 [Multi-domain] Cd Length: 167 Bit Score: 157.73 E-value: 1.66e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 373 PVFIGIGLGVLLGSIPlfipgFPAALKLGLAGGPLIMALILGRIGSIGKLywFMPPSANLALRELGIVLFLAVVGLKSGG 452
Cdd:pfam06826 1 ALFLGIALGLLLGRIK-----ISGGFSLGVAGGVLIVGLLLGHFGSTGPT--FMPISALSFLRELGLALFLAAVGLSAGP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 453 DFVATLTQGeGLSWIAYGIFITAIPLLTVGILARMLAKMNYLTLCGMLAGSMTDPPALAFANNLHATSGAAALSYATVYP 532
Cdd:pfam06826 74 GFFSSLKKD-GLLLIGLALLVTVVPLLLALVLGKYVLKLDPGLLAGLLAGALTSTPALGAANDALAGSDIPALGYAVTYP 152
|
170
....*....|....
gi 496082244 533 LVMFLRIITPQLLA 546
Cdd:pfam06826 153 FGVVGLILAGQVLA 166
|
|
| Asp-Al_Ex |
pfam06826 |
Predicted Permease Membrane Region; This family represents five transmembrane helices that are ... |
18-180 |
8.59e-36 |
|
Predicted Permease Membrane Region; This family represents five transmembrane helices that are normally found flanking (five either side) a pair of pfam02080 domains. This suggests that the paired regions form a ten helical structure, probably forming the pore, whereas the pfam02080) binds a ligand for export or regulation of the pore. Swiss:Q8L3K8 is described as a aspartate-alanine antiporter. In conjunction with Swiss:Q8L3K9 it forms a 'proton motive metabolic cycle catalyzed by an aspartate-alanine exchange'. The general conservation of domain architecture in this family suggests that they are functional orthologues.
Pssm-ID: 284291 [Multi-domain] Cd Length: 167 Bit Score: 131.54 E-value: 8.59e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 18 GLWIGNVKI-RGVGFGI-GGVLFGGIIVGHFVDQAGVALSSPMLHFIQEFGLILFVYTIGIQVGPGFFASLRVSGLRLNL 95
Cdd:pfam06826 9 GLLLGRIKIsGGFSLGVaGGVLIVGLLLGHFGSTGPTFMPISALSFLRELGLALFLAAVGLSAGPGFFSSLKKDGLLLIG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 96 FAILIVILGGLVTAVLHK-LFNIPLPVVLGIFSGAVTNTPALGAGQQILRDLGVPfevvdqmGMSYAMAYPFGICGILLT 174
Cdd:pfam06826 89 LALLVTVVPLLLALVLGKyVLKLDPGLLAGLLAGALTSTPALGAANDALAGSDIP-------ALGYAVTYPFGVVGLILA 161
|
....*.
gi 496082244 175 MWLVRL 180
Cdd:pfam06826 162 GQVLAK 167
|
|
| YidE_YbjL_dupl |
TIGR01625 |
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is ... |
18-166 |
6.99e-32 |
|
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is duplicated the aspartate-alanine antiporter AspT, as well as HI0035 of Haemophilus influenzae, YidE and YbjL of E. coli, and a number of other known or putative transporters. Member proteins may have 0, 1, or 2 copies of TrkA potassium uptake domain pfam02080 between the duplications. The domain contains several apparent transmembrane regions and is proposed here to act in transport. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 130686 [Multi-domain] Cd Length: 154 Bit Score: 120.13 E-value: 6.99e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 18 GLWIGNVKIRGVGFGI-----GGVLFGGIIVGHFVDQAGVALSSP--MLHFIQEFGLILFVYTIGIQVGPGFFASLRVSG 90
Cdd:TIGR01625 4 GLLLGKIPIGLPGFSIklgnaGGVLFVGLLLGHFGATGPLTWYIPfsANLFIREFGLMLFLYGVGLSAGPGFFSSLKDGG 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 496082244 91 --LRLNLFAILIVILGGLVTAVLHKLFNIPLPVVLGIFSGAVTNTPALGAGQQILRDlgvpfevVDQMGMSYAMAYPF 166
Cdd:TIGR01625 84 glLRINGGALITVVPTLLVAVALIKLLRINYALTAGMLAGATTNTPALDAANDTLRT-------SDLPALGYATVYPL 154
|
|
| PRK04972 |
PRK04972 |
putative transporter; Provisional |
18-550 |
5.73e-31 |
|
putative transporter; Provisional
Pssm-ID: 179905 [Multi-domain] Cd Length: 558 Bit Score: 126.76 E-value: 5.73e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 18 GLWIGNVKIRGVGFGIG-GVLFGGIIVGHfvdqAGVALSSPMLHFiqefGLILFVYTIGIQVGPGFFASLRVSGLRLNLF 96
Cdd:PRK04972 24 GLCLGKLRLGSIQLGNSiGVLVVSLLLGQ----QHFSINTDALNL----GFMLFIFCVGVEAGPNFFSIFFRDGKNYLML 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 97 AILIVILGGLVTAVLHKLFNIPLPVVLGIFSGAVTNTPALGAGQQILR-------DLGVpfeVVDQMGMSYAMAYPFGIC 169
Cdd:PRK04972 96 ALVMVGSALVIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRhsgaesrQLSL---ALDNLSLGYALTYLIGLV 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 170 GILLTMWLVRLFFRINVEKEAQRFEESSGNGHAN-----LHTINVRVENPNLNQMA----IQDVPMLNSDNIVCSRLKRG 240
Cdd:PRK04972 173 SLIVGARYLPKLQHQDLQTSAQQIARERGLDTDAqrkvyLPVIRAYRVGPELVAWTdgknLRELGIYRQTGCYIERIRRN 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 241 ELLMVPAPGTLIQAGDLLHLVGRPeDLH---NAQLVIGQEVatsLSTRGTDLKV--ERVVVTNEKVLGKKIRDLHVKQrY 315
Cdd:PRK04972 253 GILANPDGDAVLQMGDEIALVGYP-DAHarlDPSFRNGKEV---FDRDLLDMRIvtEEIVVKNHNAVGKRLSQLKLTD-H 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 316 DVVISRLNRAGVELVASSSASLQFGDILNLVGRQEAIDAVAAELGNAQQKLQQVQMLPVFIGIGLGVLLGSIPLFIPGFp 395
Cdd:PRK04972 328 GCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFIIGLMIGMITFQFSNF- 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 396 aALKLGLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLAVVGLKSGGDFVATLTQgEGLSWIAYGIFITA 475
Cdd:PRK04972 407 -SFGIGNAAGLLFAGIMLGFLRANHPTFGYIPQGALNMVKEFGLMVFMAGVGLSAGSGINNGLGA-VGGQMLIAGLIVSL 484
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 496082244 476 IPLLTVGILARMLAKMNYLTLCGMLAGSMTDPPALAFANNlHATSGAAALSYATVYPLVMFLRIITPQLLaVLFW 550
Cdd:PRK04972 485 VPVVICFLFGAYVLRMNRALLFGAIMGARTCAPAMEIISD-TARSNIPALGYAGTYAIANVLLTLAGTLI-VIVW 557
|
|
| TrkA_C |
pfam02080 |
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of ... |
291-359 |
5.18e-08 |
|
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of this domain is unknown. It has been suggested that it may bind an unidentified ligand. The domain is predicted to adopt an all beta structure.
Pssm-ID: 460440 [Multi-domain] Cd Length: 70 Bit Score: 49.92 E-value: 5.18e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 496082244 291 VERVVVTNEKVLGKKIRDLHVKQRYDVVISRLNRAGVELVASSSASLQFGDILNLVGRQEAIDAVAAEL 359
Cdd:pfam02080 2 VEVTVPENSPLVGKTLKELNLPERFGVRIVAIRRGGRLIIPSGDTVLEAGDRLLVIGTPDDLAALRELL 70
|
|
| KhtT |
COG0490 |
K+/H+ antiporter KhtSTU, c-di-AMP-binding regulatory subunit KhtT, contains RCK_C (TrkA_C) ... |
231-359 |
1.96e-04 |
|
K+/H+ antiporter KhtSTU, c-di-AMP-binding regulatory subunit KhtT, contains RCK_C (TrkA_C) domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];
Pssm-ID: 440256 [Multi-domain] Cd Length: 140 Bit Score: 41.83 E-value: 1.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 231 NIVCSRLKRGELLMVPAPGTLIQAGDLLHLVGRPEDLHNAQLVIGQEVATSLSTRGTDLKVERVVVTNE-KVLGKKIRDL 309
Cdd:COG0490 10 IILLLLLALAALLVAIVIVGVLGLILRGLLLLELALLLLLLGELLRLLTRLLIELVLLLAIEEVKVPPGsPLVGKTLGEL 89
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 496082244 310 HVKQRYDVVISRLNRAGVELVA-SSSASLQFGDILNLVGRQEAIDAVAAEL 359
Cdd:COG0490 90 NLRQRTGVTVVAIRRGGEVILSpGPDTVLEAGDTLVVVGTREQLERLEELL 140
|
|
| TrkA_C |
pfam02080 |
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of ... |
211-268 |
2.47e-04 |
|
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of this domain is unknown. It has been suggested that it may bind an unidentified ligand. The domain is predicted to adopt an all beta structure.
Pssm-ID: 460440 [Multi-domain] Cd Length: 70 Bit Score: 39.51 E-value: 2.47e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 496082244 211 VENPNLNQMAIQDVPMLNSDNIVCSRLKRGELLMVPAPGTLIQAGDLLHLVGRPEDLH 268
Cdd:pfam02080 7 PENSPLVGKTLKELNLPERFGVRIVAIRRGGRLIIPSGDTVLEAGDRLLVIGTPDDLA 64
|
|
| TrkA |
COG0569 |
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ... |
270-343 |
1.57e-03 |
|
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];
Pssm-ID: 440335 [Multi-domain] Cd Length: 296 Bit Score: 40.82 E-value: 1.57e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 496082244 270 AQLVIGQEVATSLSTRGTDLKVERVVVT-NEKVLGKKIRDLHVKQRYDVVISRLNRAGVELVASSSASLQFGDIL 343
Cdd:COG0569 221 ARLLLRPGVLDVLELADGDAEIVEVTVPeGSPLVGKTLKELDLRERYGVTVVAIKRGGEVIIPSGDTVLEAGDEL 295
|
|
| COG3273 |
COG3273 |
Uncharacterized protein, contains PhoU and TrkA_C domains [General function prediction only]; |
235-361 |
4.80e-03 |
|
Uncharacterized protein, contains PhoU and TrkA_C domains [General function prediction only];
Pssm-ID: 442504 [Multi-domain] Cd Length: 387 Bit Score: 39.65 E-value: 4.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 235 SRLKRGELLMVPAPGTLIQAGDLLHLVGRPEDLHNAQLVIGQEVATSLST--------RGTDLKVERVVVTNEKVL-GKK 305
Cdd:COG3273 251 SRLEAWVLRAARRVDDPVALRGLLHLASSTEVISDAALDIAEGVLRGLEDhpvvaeavRESDERIVRVTVPPGSPLvGKT 330
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 496082244 306 IRDLHVKQRYDVVISRLNRAG-VELVASSSASLQFGDILNLVGRQEAIDAVAAELGN 361
Cdd:COG3273 331 LGELKLETETGVRVIAIRRGGgWIYDPDGDTRLRAGDVLIVKGTREGLERLEELAGG 387
|
|
| PRK04972 |
PRK04972 |
putative transporter; Provisional |
366-513 |
6.11e-03 |
|
putative transporter; Provisional
Pssm-ID: 179905 [Multi-domain] Cd Length: 558 Bit Score: 39.32 E-value: 6.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 366 LQQVQMLPVFIGIGLGVLLGSIPLfipgfpAALKLGLAGGPLIMALILGRIGsigklYWFMPPSANLalrelGIVLFLAV 445
Cdd:PRK04972 9 LNGNYILLLFVVLALGLCLGKLRL------GSIQLGNSIGVLVVSLLLGQQH-----FSINTDALNL-----GFMLFIFC 72
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 496082244 446 VGLKSGGDFVAT-LTQGEGLSWIAYGIFITAIpLLTVGiLARMLAkMNYLTLCGMLAGSMTDPPALAFA 513
Cdd:PRK04972 73 VGVEAGPNFFSIfFRDGKNYLMLALVMVGSAL-VIALG-LGKLFG-WDIGLTAGMLAGSMTSTPVLVGA 138
|
|
| Lys_export |
pfam03956 |
Lysine exporter LysO; Members of this family contain a conserved core of four predicted ... |
35-128 |
9.37e-03 |
|
Lysine exporter LysO; Members of this family contain a conserved core of four predicted transmembrane segments. Some members have an additional pair of N-terminal transmembrane helices. This family includes lysine exporter LysO (YbjE) from E. coli.
Pssm-ID: 427613 Cd Length: 190 Bit Score: 37.40 E-value: 9.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496082244 35 GVLFGGIIVGHFVDQAGVALSSPMLhfiqEFGLILFVYTIGIQVG--PGFFASLRVSGLRLnLFAILIVILGGLVTAVL- 111
Cdd:pfam03956 2 AFFIAGILLGYFLLPPADLLLDDLS----TYALYLLLFLVGIDLGsnRSLLQILRRLGPRI-LLLPLATILGSLLGGALa 76
|
90
....*....|....*..
gi 496082244 112 HKLFNIPLPVVLGIFSG 128
Cdd:pfam03956 77 SLLLGLSLKESLAVGSG 93
|
|
|