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Conserved domains on  [gi|496081839|ref|WP_008806346|]
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MULTISPECIES: carbohydrate ABC transporter permease [Klebsiella]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 11417684)

carbohydrate ABC transporter permease, part of a periplasmic binding protein (PBP)-dependent ABC transporter may be involved in transport of one or more of a variety of mono-, di-, or polysaccharides, such as trehalose/maltose (MalG) and alginate (AlgM); responsible for translocation of the substrate across the membrane

Gene Ontology:  GO:0055085|GO:0008643
PubMed:  19234479|27273632
TCDB:  3.A.1.1.

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 23-300 1.06e-97

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 288.92  E-value: 1.06e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839  23 RREKVSRVVRYVVLIFVGLLMLYPLAWMFSASFKPNHEIFTT-LGLWPAHATWDGFINGWktgTEYHFGHYMLNTFKYVI 101
Cdd:COG0395    8 RRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGpPSLLPSEFTLENYRAAF---TDGPFGRYLLNSLIVAV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 102 PKVVLTIISSTIVAYGFARFEIPWKKFWFATLITTMLLPSTVLLIPQYLMFREMGMLNSYLPLYLPLAFATQGFFVFMLI 181
Cdd:COG0395   85 VSTVLSLLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAFGLPFGIFLLR 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 182 QFLRGVPRDMEEAAQIDGCNSIQVLWYVVVPILKPAIISVALFQFMWSMNDFIGPLIYVYSVDKYPIALALkMSIDVTEG 261
Cdd:COG0395  165 QFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGL-ASFQGQYG 243

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 496081839 262 APWNEILAMASISILPSIIVFFLAQRYFVQGVTSSGIKG 300
Cdd:COG0395  244 TDWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVKG 282
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 23-300 1.06e-97

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 288.92  E-value: 1.06e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839  23 RREKVSRVVRYVVLIFVGLLMLYPLAWMFSASFKPNHEIFTT-LGLWPAHATWDGFINGWktgTEYHFGHYMLNTFKYVI 101
Cdd:COG0395    8 RRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGpPSLLPSEFTLENYRAAF---TDGPFGRYLLNSLIVAV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 102 PKVVLTIISSTIVAYGFARFEIPWKKFWFATLITTMLLPSTVLLIPQYLMFREMGMLNSYLPLYLPLAFATQGFFVFMLI 181
Cdd:COG0395   85 VSTVLSLLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAFGLPFGIFLLR 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 182 QFLRGVPRDMEEAAQIDGCNSIQVLWYVVVPILKPAIISVALFQFMWSMNDFIGPLIYVYSVDKYPIALALkMSIDVTEG 261
Cdd:COG0395  165 QFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGL-ASFQGQYG 243

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 496081839 262 APWNEILAMASISILPSIIVFFLAQRYFVQGVTSSGIKG 300
Cdd:COG0395  244 TDWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVKG 282
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
33-296 1.17e-26

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 105.59  E-value: 1.17e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839  33 YVVLIFVGLLMLYPLAWMFSASFKPNHEIFTT-LGLWPAHATWDGFINGWKTGTEYH---FGHYMLNTFKYVIPKVVLTI 108
Cdd:PRK10973  13 HTMLILGIAVILFPLYVAFVAATLDKQAVFAVpMTLIPGTHLLENIANIWVNGVGNNsapFGRMLLNSFVMAFSITVGKI 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 109 ISSTIVAYGFARFEIPWKKFWFATLITTMLLPSTVLLIPQYLMFREMGMLNSYLPLYLPLAFATQGFFVFMliQFLRGVP 188
Cdd:PRK10973  93 TVSMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASATATFLFR--QFFMTLP 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 189 RDMEEAAQIDGCNSIQVLWYVVVPILKPAIISVALFQFMWSMNDFIGPLIYVYSVDKYPIALALKMSIDVTEGA-PWNEI 267
Cdd:PRK10973 171 DELVEAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTAVAGIKGMIATGEGTtEWNQV 250

                        250       260
                 ....*....|....*....|....*....
gi 496081839 268 LAMASISILPSIIVFFLAQRYFVQGVTSS 296
Cdd:PRK10973 251 MAAMLLTLIPPVVIVLAMQRAFVRGLVDS 279
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 93-279 2.82e-15

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 72.70  E-value: 2.82e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839  93 MLNTFKYVIPKVVLTIISSTIVAYGFARFEIPWKKFWFATLITTMLLPSTVLLIPQYLMFREMGMLNSYLPLYLP----L 168
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPalilA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 169 AFATQGFFVFMLIQFLRGVPRDMEEAAQIDGCNSIQVLWYVVVPILKPAIISVALFQFMWSMNDFIGPLIyVYSVDKYPI 248
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSF-LGGGEAPGP 159

                        170       180       190
                 ....*....|....*....|....*....|.
gi 496081839 249 ALALKMSIDVTEGAPWNEILAMASISILPSI 279
Cdd:cd06261  160 GTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 125-293 9.84e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 56.92  E-value: 9.84e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839  125 WKKFWFATLITTMLLPSTVLLIPQYLMFREMGMLNSYLPLYLPLAFATQGFFVFMLIQFLRGVPRDMEEAAQIDGCNSIQ 204
Cdd:pfam00528  16 LDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQ 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839  205 VLWYVVVPILKPAIISVALFQFMWSMNDFIGP-LIYVYSVDKYPIALALKMSiDVTEGAPwneILAMASISILPSIIVFF 283
Cdd:pfam00528  96 IFRKIILPNALPPILTGLALAFGGALGGAVLLeFLGSWPGLGLLLIEAILGY-DYPEIQG---PVLAAALILLLLNLLVD 171

                         170
                  ....*....|
gi 496081839  284 LAQRYFVQGV 293
Cdd:pfam00528 172 ILQRLLDPRV 181
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 27-238 2.50e-03

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 39.28  E-value: 2.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839   27 VSRVVRYVVLIFVGLLMLYPLAWMFSASFkpnheifttlglWPAHATWDGFINGWKTGTEYHFGHYMLNTFKYVIPKVVL 106
Cdd:TIGR03262   2 IARLLLAGMILALLLFLLLPLLALLTKSV------------YDSDGDFIGLANFAEYFATPGLLQSLGNSLTVSAIVTAI 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839  107 TIISSTIVAYGFARFEIPWKKFWFATLITTMLLPSTVLLIPQYLMFREMGMLNSYL---PLYLPL------AFATQGFFV 177
Cdd:TIGR03262  70 VVPLAFAFAYALTRSRIPGKGAFRLVALLPLLAPSLLPAISLIYLFGNQGLLKGLLggfSIYGFWgivigeVFYTFPHAL 149

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 496081839  178 FMLIQFLRGVPRDMEEAAQIDGCNSIQVLWYVVVPILKPAIISVALFQFMWSMNDFIGPLI 238
Cdd:TIGR03262 150 MILVTALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKV 210
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 23-300 1.06e-97

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 288.92  E-value: 1.06e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839  23 RREKVSRVVRYVVLIFVGLLMLYPLAWMFSASFKPNHEIFTT-LGLWPAHATWDGFINGWktgTEYHFGHYMLNTFKYVI 101
Cdd:COG0395    8 RRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGpPSLLPSEFTLENYRAAF---TDGPFGRYLLNSLIVAV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 102 PKVVLTIISSTIVAYGFARFEIPWKKFWFATLITTMLLPSTVLLIPQYLMFREMGMLNSYLPLYLPLAFATQGFFVFMLI 181
Cdd:COG0395   85 VSTVLSLLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAFGLPFGIFLLR 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 182 QFLRGVPRDMEEAAQIDGCNSIQVLWYVVVPILKPAIISVALFQFMWSMNDFIGPLIYVYSVDKYPIALALkMSIDVTEG 261
Cdd:COG0395  165 QFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGL-ASFQGQYG 243

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 496081839 262 APWNEILAMASISILPSIIVFFLAQRYFVQGVTSSGIKG 300
Cdd:COG0395  244 TDWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVKG 282
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 23-300 6.19e-56

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 182.27  E-value: 6.19e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839  23 RREKVSRVVRYVVLIFVGLLMLYPLAWMFSASFKPNHEIFTTLgLWPAHATWDGFINgwkTGTEYHFGHYMLNTFKYVIP 102
Cdd:COG3833    9 RRRRLKLGLRHLVLIILAIIALFPILWVVSASFNPGGSLYSSS-LIPENFTLENYKK---LFTETPFLRWFLNSLIVAVV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 103 KVVLTIISSTIVAYGFARFEIPWKKFWFATLITTMLLPSTVLLIPQYLMFREMGMLNSYLPLYLPLAFATQGFFVFMLIQ 182
Cdd:COG3833   85 TAIISVFLAALAAYAFSRFRFKGRKAGLLALLLLQMFPAFLALVALYLLLSALGLLNTLLGLILVYLGGAIPFNTWLMKG 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 183 FLRGVPRDMEEAAQIDGCNSIQVLWYVVVPILKPAIISVALFQFMWSMNDFIGPLIYVYSVDKYPIALALKMSIDVTEGA 262
Cdd:COG3833  165 YFDTIPKELDEAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIGPWNDFILASVLLRSPENYTLAVGLYSFVSDQRNT 244

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 496081839 263 PWNEILAMASISILPSIIVFFLAQRYFVQGVTSSGIKG 300
Cdd:COG3833  245 NWGVFAAGAVLVAIPIVILFLFLQRYLVSGLTAGGVKG 282
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
33-296 1.17e-26

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 105.59  E-value: 1.17e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839  33 YVVLIFVGLLMLYPLAWMFSASFKPNHEIFTT-LGLWPAHATWDGFINGWKTGTEYH---FGHYMLNTFKYVIPKVVLTI 108
Cdd:PRK10973  13 HTMLILGIAVILFPLYVAFVAATLDKQAVFAVpMTLIPGTHLLENIANIWVNGVGNNsapFGRMLLNSFVMAFSITVGKI 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 109 ISSTIVAYGFARFEIPWKKFWFATLITTMLLPSTVLLIPQYLMFREMGMLNSYLPLYLPLAFATQGFFVFMliQFLRGVP 188
Cdd:PRK10973  93 TVSMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASATATFLFR--QFFMTLP 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 189 RDMEEAAQIDGCNSIQVLWYVVVPILKPAIISVALFQFMWSMNDFIGPLIYVYSVDKYPIALALKMSIDVTEGA-PWNEI 267
Cdd:PRK10973 171 DELVEAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTAVAGIKGMIATGEGTtEWNQV 250

                        250       260
                 ....*....|....*....|....*....
gi 496081839 268 LAMASISILPSIIVFFLAQRYFVQGVTSS 296
Cdd:PRK10973 251 MAAMLLTLIPPVVIVLAMQRAFVRGLVDS 279
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 24-288 1.19e-23

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 97.10  E-value: 1.19e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839  24 REKVSRVVRYVVLIFVGLLMLYPLAWMFSASFKPNheifTTLGLWPAHATWDGFINGWktgTEYHFGHYMLNTFKYVIPK 103
Cdd:COG1177    1 SSRLGRLLLRLFLALVLLFLYLPILVLVLYSFNDS----WFLTFPPEGFTLRWYAELF---SDPRLLDALLNSLLIALLS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 104 VVLTIISSTIVAYGFARFEIPWKKFWFATLITTMLLPSTVLLIPQYLMFREMGMLNSYLPLYLPLAFATQGFFVFMLIQF 183
Cdd:COG1177   74 TLLATVLGTPAALALARYRFRGRRLLLALLLLPLVVPGIVLGVALLLLFSALGLSGGLWGLILAHVVFTLPFVVLVVLAR 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 184 LRGVPRDMEEAAQIDGCNSIQVLWYVVVPILKPAIISVALFQFMWSMNDFIGPL-IYVYSVDKYPIALALKMSIDVTEga 262
Cdd:COG1177  154 LQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITLfLAGPGVTTLPVYIYSMIRRGISP-- 231

                        250       260
                 ....*....|....*....|....*.
gi 496081839 263 pwnEILAMASISILPSIIVFFLAQRY 288
Cdd:COG1177  232 ---EINALSTLLILLSLLLLLLAERL 254
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
21-288 5.39e-21

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 92.53  E-value: 5.39e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839  21 TLRREKVSRVVRYVVLIFVGLLMLYPLAWMFSASFkpnheifttlglwpahatWDGFINGWKTGTEYHFGHYMLNTFKYV 100
Cdd:COG1178    2 STRPRRRPRLLLLLLALLLALLVLLPLLALLLRAF------------------TDGLANFWALLSDPYLWRALGNTLLLA 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 101 IPKVVLTIISSTIVAYGFARFEIPWKKFWFATLITTMLLPSTVLLIPQYLMFREMGMLNSYLPLYLPLAF---------- 170
Cdd:COG1178   64 LLVTLLSLLLGVPLAWLLARTDFPGRRLLRWLLLLPLALPPYVVALAWIALFGPNGLLNTLLRALFGLEPpdiyglggii 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 171 ATQGFF----VFMLI-QFLRGVPRDMEEAAQIDGCNSIQVLWYVVVPILKPAIISVALFQFMWSMNDF-----IGPLIYV 240
Cdd:COG1178  144 LVLVLFnypyVYLLLrAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFgtplvLGGGYTT 223

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 496081839 241 YSVDkypIALALKMSIDVTEGApwneilAMASISILPSIIVFFLAQRY 288
Cdd:COG1178  224 LTTA---IYQAWLGDFDLGAAA------ALALVLLLLVLLLLLLERRL 262
malG PRK10998
maltose ABC transporter permease MalG;
36-300 9.02e-18

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 81.68  E-value: 9.02e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839  36 LIFVGLlMLYPLAWMFSASFKPNHeiFTTLGLWPAHATWDGfingWKTGTEYHFGH--------------YMLNTFKYVI 101
Cdd:PRK10998  21 LGFIAL-IMFPLLMVIAISLREGN--FATGSLIPEQISWEH----WKLALGFSVEHadgrvtpppfpvllWLWNSVKVAG 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 102 PKVVLTIISSTIVAYGFARFEIPWKKFWFATLITTMLLPSTVLLIPQYLMFREMGMLNSYLPL--YLPLAFATQG---FF 176
Cdd:PRK10998  94 ITAIGIVALSTTCAYAFARMRFKGKATLLKGMLIFQMFPAVLSLVALYALFDRLGQYIPFIGLntHGGVIFAYLGgiaLH 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 177 VFMLIQFLRGVPRDMEEAAQIDGCNSIQVLWYVVVPILKPAIISVALFQFMWSMNDFIGPLIYVYSVDKYPIALALKMSI 256
Cdd:PRK10998 174 VWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDVNSYTLAVGMQQYL 253

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 496081839 257 DvTEGAPWNEILAMASISILPSIIVFFLAQRYFVQGVTSSGIKG 300
Cdd:PRK10998 254 N-PQNYLWGDFAAAAVLSAIPITVVFLLAQRWLVGGLTAGGVKG 296
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
11-240 2.29e-17

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 80.56  E-value: 2.29e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839  11 MSNADREVARTLRREKvsRVVRYV----VLIFVGLLMLYPLAWMFSASFkpnheifTTLGLWPAHATWDGFINGWKTGTE 86
Cdd:COG1175    1 MTTTTSAAARRRRRRR--RLAAYLfllpALLLLLVFVLYPLLYTLYLSF-------TDWNLLGPPPEFVGLDNYARLFTD 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839  87 YHFGHYMLNTFKYVIPKVVLTIISSTIVAYGFARfEIPWKKFWFATLITTMLLPSTVL-LIPQYLMFREMGMLNSYL--- 162
Cdd:COG1175   72 PRFWNALGNTLLFTVVSVPLQLVLGLLLALLLNR-KLRGRGFFRTLFFLPWVISPVVVaLIWKWLFNPDYGLLNALLgal 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 163 -----------PLYLPLAFATQ-----GFFVFMLIQFLRGVPRDMEEAAQIDGCNSIQVLWYVVVPILKPAIISVALFQF 226
Cdd:COG1175  151 glepinwlgdpSLALPAVIIVTvwkgtGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLST 230

                        250
                 ....*....|....
gi 496081839 227 MWSMNDFigPLIYV 240
Cdd:COG1175  231 IGALQVF--DLVYV 242
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 93-279 2.82e-15

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 72.70  E-value: 2.82e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839  93 MLNTFKYVIPKVVLTIISSTIVAYGFARFEIPWKKFWFATLITTMLLPSTVLLIPQYLMFREMGMLNSYLPLYLP----L 168
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPalilA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 169 AFATQGFFVFMLIQFLRGVPRDMEEAAQIDGCNSIQVLWYVVVPILKPAIISVALFQFMWSMNDFIGPLIyVYSVDKYPI 248
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSF-LGGGEAPGP 159

                        170       180       190
                 ....*....|....*....|....*....|.
gi 496081839 249 ALALKMSIDVTEGAPWNEILAMASISILPSI 279
Cdd:cd06261  160 GTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
19-287 1.27e-11

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 64.80  E-value: 1.27e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839  19 ARTLRREKVSRVVRYVVLIFVGLLMLYPLAWMFSASFkpnheifttLGLWPAHATWDGFINGWKTGTeyhFGHYMLNTFK 98
Cdd:COG1178  278 PRRVKLGRWRWLALALCLLLVLLGLLLPLLALLLWSL---------TKALDDNLTLDNYRFVLLDPS---LLRALLNSLL 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839  99 YVIPKVVLTIISSTIVAYGFARFEIPWKKFWFATLITTMLLPSTVLLIPQYLMFREMGMLNSYL-PLYLPLAFAtqgfFV 177
Cdd:COG1178  346 LALLAALLAVLLALLLAYLVRRRRGRLARLLDRLAMLPYAVPGIVLGLGLLLLFNRPLPLLLYGtLAILVLAYV----VR 421

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 178 FM------LIQFLRGVPRDMEEAAQIDGCNSIQVLWYVVVPILKPAIISVALFQFMWSMNDFiGPLIYVYSVDKYPIALA 251
Cdd:COG1178  422 FLpfalrsLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKEL-SATLLLRPPGFETLAVL 500

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 496081839 252 LKmsiDVTEGAPWNEILAMASISILPSIIVFFLAQR 287
Cdd:COG1178  501 IY---QLASSGRYGEAAALALLLVLVSLLPVLLLER 533
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 34-220 7.24e-10

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 58.61  E-value: 7.24e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839  34 VVLIFVGLLMLYPLAWMFsasfkpnheifttlgLWPAHATWDGFingWKTGTEYHFGHYMLNTFKYVIPKVVLTIISSTI 113
Cdd:COG0555   15 LTLLYLSLIVLLPLAALV---------------LKAAGLGWAEF---WAVLTSPRVLAALKLSLGTALIAALINLVFGLP 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 114 VAYGFARFEIPWKKFwFATLITT-MLLPSTVLLIPQYLMFREMGMLNSYL-PLYLPLAFATQG-----FFV---FMLIQF 183
Cdd:COG0555   77 LAWVLVRYRFPGKRL-VDALVDLpFALPTAVAGIALLLLFGPNGWLGQLLaPLGIKVAFTPLGivlaqTFVslpFVVRTV 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 496081839 184 ---LRGVPRDMEEAAQIDGCNSIQVLWYVVVPILKPAIIS 220
Cdd:COG0555  156 qpvLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLT 195
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 125-293 9.84e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 56.92  E-value: 9.84e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839  125 WKKFWFATLITTMLLPSTVLLIPQYLMFREMGMLNSYLPLYLPLAFATQGFFVFMLIQFLRGVPRDMEEAAQIDGCNSIQ 204
Cdd:pfam00528  16 LDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQ 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839  205 VLWYVVVPILKPAIISVALFQFMWSMNDFIGP-LIYVYSVDKYPIALALKMSiDVTEGAPwneILAMASISILPSIIVFF 283
Cdd:pfam00528  96 IFRKIILPNALPPILTGLALAFGGALGGAVLLeFLGSWPGLGLLLIEAILGY-DYPEIQG---PVLAAALILLLLNLLVD 171

                         170
                  ....*....|
gi 496081839  284 LAQRYFVQGV 293
Cdd:pfam00528 172 ILQRLLDPRV 181
cysT CHL00187
sulfate transport protein; Provisional
 113-233 5.28e-07

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 49.63  E-value: 5.28e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 113 IVAYGFARFEIPWKKFWFATLITTMLLPSTVL------------LIPQYLMFREMGMLNSYLPLYLPLAFATQGFFVFML 180
Cdd:CHL00187  77 LIAWVLVRYNFPGKRLLDAAVDLPFALPTSVAgltlatvygdngWIGHLLSHLGIQIVFTKLGVLLAMIFVSFPFVVRTI 156

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 496081839 181 IQFLRGVPRDMEEAAQIDGCNSIQVLWYVVVPILKPAIISVALFQFMWSMNDF 233
Cdd:CHL00187 157 QPVLQEIEKELEEAAWSLGASPWQTFWKVIFPPLIPALLTGLALTFSRAIGEY 209
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 107-287 1.21e-04

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 42.66  E-value: 1.21e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 107 TIISsTIVAYGFARFEIPWKKFWFATLITTMLLPSTVLLIPQYLMFREMGMLNSYLPLYLPLAFATQGFFVFMLIQFLRG 186
Cdd:PRK09500  74 TLIG-SLTAVALYRYRFRGKKFVSGMLFVVMMSPDIVMAISLLVLFMLLGIQLGFWSLLFAHITFCLPFVVVTVYSRLKG 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 187 VPRDMEEAAQIDGCNSIQVLWYVVVPILKPAIISVALFQFMWSMNDFI------GPliyvysvdKYPIaLALKMSIDVTE 260
Cdd:PRK09500 153 FDVRMLEAAKDLGASEFTILRKIILPLALPAVAAGWLLSFTLSLDDVVvssfvtGP--------SYEI-LPLKIYSMVKV 223

                        170       180
                 ....*....|....*....|....*..
gi 496081839 261 GAPwNEILAMASISILPSIIVFFLAQR 287
Cdd:PRK09500 224 GVS-PEVNALATILLVLSLVLVILSQL 249
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 27-238 2.50e-03

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 39.28  E-value: 2.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839   27 VSRVVRYVVLIFVGLLMLYPLAWMFSASFkpnheifttlglWPAHATWDGFINGWKTGTEYHFGHYMLNTFKYVIPKVVL 106
Cdd:TIGR03262   2 IARLLLAGMILALLLFLLLPLLALLTKSV------------YDSDGDFIGLANFAEYFATPGLLQSLGNSLTVSAIVTAI 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839  107 TIISSTIVAYGFARFEIPWKKFWFATLITTMLLPSTVLLIPQYLMFREMGMLNSYL---PLYLPL------AFATQGFFV 177
Cdd:TIGR03262  70 VVPLAFAFAYALTRSRIPGKGAFRLVALLPLLAPSLLPAISLIYLFGNQGLLKGLLggfSIYGFWgivigeVFYTFPHAL 149

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 496081839  178 FMLIQFLRGVPRDMEEAAQIDGCNSIQVLWYVVVPILKPAIISVALFQFMWSMNDFIGPLI 238
Cdd:TIGR03262 150 MILVTALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKV 210
PRK10592 PRK10592
putrescine transporter subunit: membrane component of ABC superfamily; Provisional
 184-288 6.55e-03

putrescine transporter subunit: membrane component of ABC superfamily; Provisional


Pssm-ID: 182574  Cd Length: 281  Bit Score: 37.52  E-value: 6.55e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496081839 184 LRGVPRDMEEAAQIDGCNSIQVLWYVVVPILKPAIISVALFQFMWSMNDFIgpliyVYSVDKYPIALALKMSIDVTEGAP 263
Cdd:PRK10592 163 LRELDRSIEEAAMDLGATPLKVFFVITLPMIMPAIISGWLLAFTLSLDDLV-----IASFVSGPGATTLPMLVFSSVRMG 237

                         90       100
                 ....*....|....*....|....*.
gi 496081839 264 WN-EILAMASISILPSIIVFFLAQRY 288
Cdd:PRK10592 238 VNpEINALATLILGVVGIVGFIAWYL 263
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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