|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
1-1049 |
0e+00 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 2141.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISATYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
Cdd:PRK15127 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 81 NSDSTGTVQITLTFQSGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTNGTMTQEDISDYVGA 160
Cdd:PRK15127 81 NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 161 NMKDAISRTSGVGDVQLFGSQYAMRIWMDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
Cdd:PRK15127 161 NMKDPISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 241 TSADEFSKILLKVNQDGSQVRLRDVAKVELGGENYDIIAKFNGKPASGLGIKLATGANALDTANAIRDELKKMEPFFPSG 320
Cdd:PRK15127 241 TSTEEFGKILLKVNQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 321 LKIVYPYDTTPFVKISIHEVVKTLAEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAIFGFSINTLTMFGMVL 400
Cdd:PRK15127 321 LKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480
Cdd:PRK15127 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFDKSTHHYTDSVGGILRSTGRYLALYLIIVVGMAYLFVRLP 560
Cdd:PRK15127 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGNILRSTGRYLVLYLIIVVGMAYLFVRLP 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 561 SSFLPDEDQGVFLSMAQLPAGATQERTQKVLDEMTDYYLTKEKANVESVFAVNGFGFAGRGQNTGIAFVSLKDWSERPGK 640
Cdd:PRK15127 561 SSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGE 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 641 ENKVEAITQRAMGAFSQIKDAMVFAFNLPAIVELGTATGFDFQLIDQAGLGHEKLTQARNQLFGEVAKHPDLLVGVRPNG 720
Cdd:PRK15127 641 ENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLGEAAKHPDMLVGVRPNG 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPEDIGNWYVRGSDGQMVP 800
Cdd:PRK15127 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVP 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 801 FSAFSTSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMAMMEQLASKLPSGIGYDWTGMSYQERLSGNQAPALYAIS 880
Cdd:PRK15127 801 FSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEELASKLPTGVGYDWTGMSYQERLSGNQAPALYAIS 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960
Cdd:PRK15127 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 961 IEATLDAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRKNEDI 1040
Cdd:PRK15127 961 IEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRKNEDI 1040
|
....*....
gi 496059457 1041 EHSHSVEHH 1049
Cdd:PRK15127 1041 EHSHTVDHH 1049
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
1-1046 |
0e+00 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 1904.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISATYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
Cdd:TIGR00915 1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 81 NSDSTGTVQITLTFQSGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTNGTMTQEDISDYVGA 160
Cdd:TIGR00915 81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 161 NMKDAISRTSGVGDVQLFGSQYAMRIWMDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
Cdd:TIGR00915 161 NMVDPLSRLEGVGDVQLFGSQYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGQQLNATIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 241 TSADEFSKILLKVNQDGSQVRLRDVAKVELGGENYDIIAKFNGKPASGLGIKLATGANALDTANAIRDELKKMEPFFPSG 320
Cdd:TIGR00915 241 QTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 321 LKIVYPYDTTPFVKISIHEVVKTLAEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAIFGFSINTLTMFGMVL 400
Cdd:TIGR00915 321 MKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480
Cdd:TIGR00915 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFDKSTHHYTDSVGGILRSTGRYLALYLIIVVGMAYLFVRLP 560
Cdd:TIGR00915 481 SVLVALILTPALCATMLKPIEKGEHHEKKGGFFGWFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLP 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 561 SSFLPDEDQGVFLSMAQLPAGATQERTQKVLDEMTDYYLTKEKANVESVFAVNGFGFAGRGQNTGIAFVSLKDWSERPGK 640
Cdd:TIGR00915 561 TSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEKANVESVFTVNGFSFAGRGQNMGMAFIRLKDWEERTGK 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 641 ENKVEAITQRAMGAFSQIKDAMVFAFNLPAIVELGTATGFDFQLIDQAGLGHEKLTQARNQLFGEVAKHPDlLVGVRPNG 720
Cdd:TIGR00915 641 ENSVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQNPA-LTRVRPNG 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPEDIGNWYVRGSDGQMVP 800
Cdd:TIGR00915 720 LEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNASGEMVP 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 801 FSAFSTSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMAMMEQLASKLPSGIGYDWTGMSYQERLSGNQAPALYAIS 880
Cdd:TIGR00915 800 FSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQKLPPGFGFSWTGMSYEERLSGSQAPALYALS 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKeGKGL 960
Cdd:TIGR00915 880 LLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKELMAQ-GKSI 958
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 961 IEATLDAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRKNEDI 1040
Cdd:TIGR00915 959 VEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVRRLFKRKAHEK 1038
|
....*.
gi 496059457 1041 EHSHSV 1046
Cdd:TIGR00915 1039 EMSVEH 1044
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
1-1019 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 1483.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISATYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 81 NSdSTGTVQITLTFQSGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTNGTMTQEDISDYVGA 160
Cdd:pfam00873 81 QS-SYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 161 NMKDAISRTSGVGDVQLFG-SQYAMRIWMDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLggtppvKGQQLNASIIAQTR 239
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGgSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQL------EGQGLQALIRAQGQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 240 LTSADEFSKILLKvNQDGSQVRLRDVAKVELGGENYDIIAKFNGKPASGLGIKLATGANALDTANAIRDELKKMEPFFPS 319
Cdd:pfam00873 234 LQSAEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 320 GLKIVYPYDTTPFVKISIHEVVKTLAEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAIFGFSINTLTMFGMV 399
Cdd:pfam00873 313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 400 LAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479
Cdd:pfam00873 393 LAIGLVVDDAIVVVENIERVLEENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 480 LSVLVALILTPALCATMLKPIAKGDHGegkkGFFGWFNRMFDKSTHHYTDSVGGILRSTGRYLALYLIIVVGMAYLFVRL 559
Cdd:pfam00873 473 LSVLVALTLTPALCATLLKPRREPKHG----GFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRI 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 560 PSSFLPDEDQGVFLSMAQLPAGATQERTQKVLDEMTDYYltKEKANVESVFAVNGFGFAG--RGQNTGIAFVSLKDWSER 637
Cdd:pfam00873 549 PTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKIL--KEKPEVESVFAVTGFAFSGdnNGPNSGDAFISLKPWKER 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 638 PGKENKVEAITQRAMGAFSQIKDAMVFAFNLPAIVELGTATGFDFQLID-QAGLGHEKLTQARNQLFGEVAKHPDlLVGV 716
Cdd:pfam00873 627 PGPEKSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLPG-LSDV 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 717 RPNGLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPEDIGNWYVRGSDG 796
Cdd:pfam00873 706 RSDGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYG 785
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 797 QMVPFSAFSTSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMAMMEQLASK--LPSGIGYDWTGMSYQERLSGNQAP 874
Cdd:pfam00873 786 KMIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQvkLPPGYGYTWTGQFEQEQLAGNSLP 865
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 875 ALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMD 954
Cdd:pfam00873 866 ILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELRE 945
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 496059457 955 KEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAI 1019
Cdd:pfam00873 946 QEGKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTL 1010
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1019 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1251.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISATYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
Cdd:COG0841 3 LSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYITS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 81 NSdSTGTVQITLTFQSGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVinTNGTMTQEDISDYVGA 160
Cdd:COG0841 83 TS-SEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLAL--SSDDLDELELSDYAER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 161 NMKDAISRTSGVGDVQLFGS-QYAMRIWMDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLGGtppvkgQQLNASIIAQTR 239
Cdd:COG0841 160 NIKDRLERVPGVGQVQIFGGrEREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGG------GDREYTVRTNGR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 240 LTSADEFSKILLKVNqDGSQVRLRDVAKVELGGENYDIIAKFNGKPASGLGIKLATGANALDTANAIRDELKKMEPFFPS 319
Cdd:COG0841 234 LKTPEEFENIVIRTN-DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPE 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 320 GLKIVYPYDTTPFVKISIHEVVKTLAEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAIFGFSINTLTMFGMV 399
Cdd:COG0841 313 GVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 400 LAIGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479
Cdd:COG0841 393 LAIGIVVDDAIVVVENIERHM-EEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALL 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 480 LSVLVALILTPALCATMLKPiakgDHGEGKKGFFGWFNRMFDKSTHHYTDSVGGILRSTGRYLALYLIIVVGMAYLFVRL 559
Cdd:COG0841 472 ISLFVALTLTPALCARLLKP----HPKGKKGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRL 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 560 PSSFLPDEDQGVFLSMAQLPAGATQERTQKVLDEMTDYYLtkEKANVESVFAVNGFGFAGRGQNTGIAFVSLKDWSERPg 639
Cdd:COG0841 548 PTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILL--EVPEVESVFSVVGFSGGGSGSNSGTIFVTLKPWDERD- 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 640 keNKVEAITQRAMGAFSQIKDAMVFAFNLPAIvELGTATGFDFQLidqAGLGHEKLTQARNQLFGEVAKHPdLLVGVRPN 719
Cdd:COG0841 625 --RSADEIIARLREKLAKIPGARVFVFQPPAG-GLGSGAPIEVQL---QGDDLEELAAAAEKLLAALRQIP-GLVDVRSD 697
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 720 GLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPEDIGNWYVRGSDGQMV 799
Cdd:COG0841 698 LQLGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMV 777
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 800 PFSAFSTSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMAMMEQLASK--LPSGIGYDWTGMSYQERLSGNQAPALY 877
Cdd:COG0841 778 PLSSVATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAElkLPPGVSIEFTGQAEEEQESFSSLGLAF 857
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 878 AISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMdKEG 957
Cdd:COG0841 858 LLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLR-EEG 936
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 496059457 958 KGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAI 1019
Cdd:COG0841 937 MSLREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTL 998
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
5-1017 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 776.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 5 FIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISATYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSdS 84
Cdd:NF033617 4 FIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQS-S 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 85 TGTVQITLTFQSGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVE-KSSSSFLMVVGVinTNGTMTQEDISDYVGANMK 163
Cdd:NF033617 83 LGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVYRKaNSADTPIMYIGL--TSEEMPRGQLTDYAERVLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 164 DAISRTSGVGDVQLFGSQY-AMRIWMDPNKLNNFQLTPVDVISAIKAQNAQVAAGQlggtppVKGQQLNASIIAQTRLTS 242
Cdd:NF033617 161 PKLSQINGVGSVDVSGGQRpAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGA------VRGDSVVSTVRANDQLKT 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 243 ADEFSKILLKVNQDGSQVRLRDVAKVELGGENYDIIAKFNGKPASGLGIKLATGANALDTANAIRDELKKMEPFFPSGLK 322
Cdd:NF033617 235 AEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIK 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 323 IVYPYDTTPFVKISIHEVVKTLAEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAIFGFSINTLTMFGMVLAI 402
Cdd:NF033617 315 VNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAI 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 403 GLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSV 482
Cdd:NF033617 395 GLVVDDAIVVVENIHRHI-EEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISG 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 483 LVALILTPALCATMLKPIAKGDhgegkkGFFGWFNRMFDKSTHHYTDSVGGILRSTGRYLALYLIIVVGMAYLFVRLPSS 562
Cdd:NF033617 474 IVALTLTPMMCSRLLKANEKPG------RFARAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKE 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 563 FLPDEDQGVFLSMAQLPAGATQERTQKVLDEMTDYYLTKEKanVESVFAVNGFGfAGRGQNTGIAFVSLKDWSERpgkEN 642
Cdd:NF033617 548 LAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPE--VQSLTSFNGVG-GNPGDNTGFGIINLKPWDER---DV 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 643 KVEAITQRAMGAFSQIKDAMVFAFNLPAIvELGTATGFDFQLIDQAGLGHEKLTQARNQLFGEVAKHPdLLVGVRPNGLE 722
Cdd:NF033617 622 SAQEIIDRLRPKLAKVPGMDLFLFPLQDL-PGGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSP-QFADVDSDLQD 699
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 723 DTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPEDIGNWYVRGSDGQMVPFS 802
Cdd:NF033617 700 KGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPLS 779
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 803 AFSTSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMAMMEQLA-SKLPSGIGYDWTGMSYQERLSGNQAPALYAISL 881
Cdd:NF033617 780 TLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQAAkELLPSGISGSFQGAARAFQEEGSSLLFLFLLAL 859
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 882 IVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLI 961
Cdd:NF033617 860 AAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELQRHQGLSRR 939
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*.
gi 496059457 962 EATLDAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVL 1017
Cdd:NF033617 940 EAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLF 995
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
189-487 |
1.61e-03 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 42.46 E-value: 1.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 189 DPN-KLNNFQLTPVDVISAIKAQNAQVAAGQLGGTPPVkGQQLNASIIAQTRLTSADEFSKILL-KVNqdgsqvrlrdva 266
Cdd:NF037998 308 DPNsKTEDFNGTKGKYIDPLKLYLSQNATPQLMKIDEV-FKVLNGLILSFNDKTTTSNFNQYLDeKIK------------ 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 267 kvelggeNYDIIAKFNGKPASGLGIKLATGANALDTANAIRDELKKMEPFF---PSGLKIV------YPYDTTPFVKISI 337
Cdd:NF037998 375 -------NYILNNDTINGTKTGAGAGSNTNSNQLIVATSTETIARTIEALInqtTSGFTFKvngiseFNPVVTLLMLIAS 447
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 338 HEVVKTLAEAIILVFLVMYLFLQNFraTLIptIAVPVVLLgTFAVLAIFGFSINTLTMFGMVLAIGLLVDDAIVVVENVE 417
Cdd:NF037998 448 IIFLLILAIAIMIYLLFAYRLLGLF--AII--IALTSISL-TLYSPTWFGLAIGPESITAIFIAIGLVLESCSLLFEAFK 522
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 496059457 418 RVMAEEGLPPKEATRKSMGQIQGALVGIAMVLsavFIP-MAFFGGSTGAIyRQFSITIVSAMALSVLVALI 487
Cdd:NF037998 523 KHLYKNKRSIEESFKIANKETIGIIVDALVVL---LIPnLSLFWIGSNSI-KSFATILLVGVIISLVLVII 589
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
1-1049 |
0e+00 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 2141.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISATYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
Cdd:PRK15127 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 81 NSDSTGTVQITLTFQSGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTNGTMTQEDISDYVGA 160
Cdd:PRK15127 81 NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 161 NMKDAISRTSGVGDVQLFGSQYAMRIWMDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
Cdd:PRK15127 161 NMKDPISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 241 TSADEFSKILLKVNQDGSQVRLRDVAKVELGGENYDIIAKFNGKPASGLGIKLATGANALDTANAIRDELKKMEPFFPSG 320
Cdd:PRK15127 241 TSTEEFGKILLKVNQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 321 LKIVYPYDTTPFVKISIHEVVKTLAEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAIFGFSINTLTMFGMVL 400
Cdd:PRK15127 321 LKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480
Cdd:PRK15127 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFDKSTHHYTDSVGGILRSTGRYLALYLIIVVGMAYLFVRLP 560
Cdd:PRK15127 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGNILRSTGRYLVLYLIIVVGMAYLFVRLP 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 561 SSFLPDEDQGVFLSMAQLPAGATQERTQKVLDEMTDYYLTKEKANVESVFAVNGFGFAGRGQNTGIAFVSLKDWSERPGK 640
Cdd:PRK15127 561 SSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGE 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 641 ENKVEAITQRAMGAFSQIKDAMVFAFNLPAIVELGTATGFDFQLIDQAGLGHEKLTQARNQLFGEVAKHPDLLVGVRPNG 720
Cdd:PRK15127 641 ENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLGEAAKHPDMLVGVRPNG 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPEDIGNWYVRGSDGQMVP 800
Cdd:PRK15127 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVP 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 801 FSAFSTSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMAMMEQLASKLPSGIGYDWTGMSYQERLSGNQAPALYAIS 880
Cdd:PRK15127 801 FSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEELASKLPTGVGYDWTGMSYQERLSGNQAPALYAIS 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960
Cdd:PRK15127 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 961 IEATLDAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRKNEDI 1040
Cdd:PRK15127 961 IEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRKNEDI 1040
|
....*....
gi 496059457 1041 EHSHSVEHH 1049
Cdd:PRK15127 1041 EHSHTVDHH 1049
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
1-1046 |
0e+00 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 1904.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISATYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
Cdd:TIGR00915 1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 81 NSDSTGTVQITLTFQSGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTNGTMTQEDISDYVGA 160
Cdd:TIGR00915 81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 161 NMKDAISRTSGVGDVQLFGSQYAMRIWMDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
Cdd:TIGR00915 161 NMVDPLSRLEGVGDVQLFGSQYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGQQLNATIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 241 TSADEFSKILLKVNQDGSQVRLRDVAKVELGGENYDIIAKFNGKPASGLGIKLATGANALDTANAIRDELKKMEPFFPSG 320
Cdd:TIGR00915 241 QTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 321 LKIVYPYDTTPFVKISIHEVVKTLAEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAIFGFSINTLTMFGMVL 400
Cdd:TIGR00915 321 MKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480
Cdd:TIGR00915 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFDKSTHHYTDSVGGILRSTGRYLALYLIIVVGMAYLFVRLP 560
Cdd:TIGR00915 481 SVLVALILTPALCATMLKPIEKGEHHEKKGGFFGWFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLP 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 561 SSFLPDEDQGVFLSMAQLPAGATQERTQKVLDEMTDYYLTKEKANVESVFAVNGFGFAGRGQNTGIAFVSLKDWSERPGK 640
Cdd:TIGR00915 561 TSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEKANVESVFTVNGFSFAGRGQNMGMAFIRLKDWEERTGK 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 641 ENKVEAITQRAMGAFSQIKDAMVFAFNLPAIVELGTATGFDFQLIDQAGLGHEKLTQARNQLFGEVAKHPDlLVGVRPNG 720
Cdd:TIGR00915 641 ENSVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQNPA-LTRVRPNG 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPEDIGNWYVRGSDGQMVP 800
Cdd:TIGR00915 720 LEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNASGEMVP 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 801 FSAFSTSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMAMMEQLASKLPSGIGYDWTGMSYQERLSGNQAPALYAIS 880
Cdd:TIGR00915 800 FSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQKLPPGFGFSWTGMSYEERLSGSQAPALYALS 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKeGKGL 960
Cdd:TIGR00915 880 LLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKELMAQ-GKSI 958
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 961 IEATLDAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRKNEDI 1040
Cdd:TIGR00915 959 VEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVRRLFKRKAHEK 1038
|
....*.
gi 496059457 1041 EHSHSV 1046
Cdd:TIGR00915 1039 EMSVEH 1044
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
1-1019 |
0e+00 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 1617.21 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISATYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
Cdd:PRK10555 1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 81 NSDSTGTVQITLTFQSGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTNGTMTQEDISDYVGA 160
Cdd:PRK10555 81 QSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 161 NMKDAISRTSGVGDVQLFGSQYAMRIWMDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
Cdd:PRK10555 161 NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 241 TSADEFSKILLKVNQDGSQVRLRDVAKVELGGENYDIIAKFNGKPASGLGIKLATGANALDTANAIRDELKKMEPFFPSG 320
Cdd:PRK10555 241 QTPEQFRDITLRVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPHG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 321 LKIVYPYDTTPFVKISIHEVVKTLAEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAIFGFSINTLTMFGMVL 400
Cdd:PRK10555 321 LEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480
Cdd:PRK10555 401 AIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 481 SVLVALILTPALCATMLKPIAKGDHgEGKKGFFGWFNRMFDKSTHHYTDSVGGILRSTGRYLALYLIIVVGMAYLFVRLP 560
Cdd:PRK10555 481 SVLVAMILTPALCATLLKPLKKGEH-HGQKGFFGWFNRMFNRNAERYEKGVAKILHRSLRWILIYVLLLGGMVFLFLRLP 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 561 SSFLPDEDQGVFLSMAQLPAGATQERTQKVLDEMTDYYLTKEKANVESVFAVNGFGFAGRGQNTGIAFVSLKDWSERPGK 640
Cdd:PRK10555 560 TSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYFTHEKDNVMSVFATVGSGPGGNGQNVARMFIRLKDWDERDSK 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 641 ENKVEAITQRAMGAFSQIKDAMVFAFNLPAIVELGTATGFDFQLIDQAGLGHEKLTQARNQLFGEVAKHPdLLVGVRPNG 720
Cdd:PRK10555 640 TGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAKNP-ELTRVRHNG 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPEDIGNWYVRGSDGQMVP 800
Cdd:PRK10555 719 LDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVP 798
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 801 FSAFSTSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMAMMEQLASKLPSGIGYDWTGMSYQERLSGNQAPALYAIS 880
Cdd:PRK10555 799 FSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAIS 878
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDlMDKEGKGL 960
Cdd:PRK10555 879 LLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANE-MNQKGHDL 957
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*....
gi 496059457 961 IEATLDAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAI 1019
Cdd:PRK10555 958 FEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATILAI 1016
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
1-1019 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 1483.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISATYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 81 NSdSTGTVQITLTFQSGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTNGTMTQEDISDYVGA 160
Cdd:pfam00873 81 QS-SYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 161 NMKDAISRTSGVGDVQLFG-SQYAMRIWMDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLggtppvKGQQLNASIIAQTR 239
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGgSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQL------EGQGLQALIRAQGQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 240 LTSADEFSKILLKvNQDGSQVRLRDVAKVELGGENYDIIAKFNGKPASGLGIKLATGANALDTANAIRDELKKMEPFFPS 319
Cdd:pfam00873 234 LQSAEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 320 GLKIVYPYDTTPFVKISIHEVVKTLAEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAIFGFSINTLTMFGMV 399
Cdd:pfam00873 313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 400 LAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479
Cdd:pfam00873 393 LAIGLVVDDAIVVVENIERVLEENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 480 LSVLVALILTPALCATMLKPIAKGDHGegkkGFFGWFNRMFDKSTHHYTDSVGGILRSTGRYLALYLIIVVGMAYLFVRL 559
Cdd:pfam00873 473 LSVLVALTLTPALCATLLKPRREPKHG----GFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRI 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 560 PSSFLPDEDQGVFLSMAQLPAGATQERTQKVLDEMTDYYltKEKANVESVFAVNGFGFAG--RGQNTGIAFVSLKDWSER 637
Cdd:pfam00873 549 PTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKIL--KEKPEVESVFAVTGFAFSGdnNGPNSGDAFISLKPWKER 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 638 PGKENKVEAITQRAMGAFSQIKDAMVFAFNLPAIVELGTATGFDFQLID-QAGLGHEKLTQARNQLFGEVAKHPDlLVGV 716
Cdd:pfam00873 627 PGPEKSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLPG-LSDV 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 717 RPNGLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPEDIGNWYVRGSDG 796
Cdd:pfam00873 706 RSDGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYG 785
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 797 QMVPFSAFSTSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMAMMEQLASK--LPSGIGYDWTGMSYQERLSGNQAP 874
Cdd:pfam00873 786 KMIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQvkLPPGYGYTWTGQFEQEQLAGNSLP 865
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 875 ALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMD 954
Cdd:pfam00873 866 ILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELRE 945
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 496059457 955 KEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAI 1019
Cdd:pfam00873 946 QEGKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTL 1010
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1019 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1251.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISATYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
Cdd:COG0841 3 LSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYITS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 81 NSdSTGTVQITLTFQSGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVinTNGTMTQEDISDYVGA 160
Cdd:COG0841 83 TS-SEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLAL--SSDDLDELELSDYAER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 161 NMKDAISRTSGVGDVQLFGS-QYAMRIWMDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLGGtppvkgQQLNASIIAQTR 239
Cdd:COG0841 160 NIKDRLERVPGVGQVQIFGGrEREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGG------GDREYTVRTNGR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 240 LTSADEFSKILLKVNqDGSQVRLRDVAKVELGGENYDIIAKFNGKPASGLGIKLATGANALDTANAIRDELKKMEPFFPS 319
Cdd:COG0841 234 LKTPEEFENIVIRTN-DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPE 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 320 GLKIVYPYDTTPFVKISIHEVVKTLAEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAIFGFSINTLTMFGMV 399
Cdd:COG0841 313 GVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 400 LAIGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479
Cdd:COG0841 393 LAIGIVVDDAIVVVENIERHM-EEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALL 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 480 LSVLVALILTPALCATMLKPiakgDHGEGKKGFFGWFNRMFDKSTHHYTDSVGGILRSTGRYLALYLIIVVGMAYLFVRL 559
Cdd:COG0841 472 ISLFVALTLTPALCARLLKP----HPKGKKGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRL 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 560 PSSFLPDEDQGVFLSMAQLPAGATQERTQKVLDEMTDYYLtkEKANVESVFAVNGFGFAGRGQNTGIAFVSLKDWSERPg 639
Cdd:COG0841 548 PTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILL--EVPEVESVFSVVGFSGGGSGSNSGTIFVTLKPWDERD- 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 640 keNKVEAITQRAMGAFSQIKDAMVFAFNLPAIvELGTATGFDFQLidqAGLGHEKLTQARNQLFGEVAKHPdLLVGVRPN 719
Cdd:COG0841 625 --RSADEIIARLREKLAKIPGARVFVFQPPAG-GLGSGAPIEVQL---QGDDLEELAAAAEKLLAALRQIP-GLVDVRSD 697
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 720 GLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPEDIGNWYVRGSDGQMV 799
Cdd:COG0841 698 LQLGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMV 777
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 800 PFSAFSTSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMAMMEQLASK--LPSGIGYDWTGMSYQERLSGNQAPALY 877
Cdd:COG0841 778 PLSSVATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAElkLPPGVSIEFTGQAEEEQESFSSLGLAF 857
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 878 AISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMdKEG 957
Cdd:COG0841 858 LLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLR-EEG 936
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 496059457 958 KGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAI 1019
Cdd:COG0841 937 MSLREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTL 998
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
1-1019 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 1230.49 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISATYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
Cdd:PRK09577 1 MARFFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 81 NSdSTGTVQITLTFQSGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTNGTMTQEDISDYVGA 160
Cdd:PRK09577 81 TS-SAGQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVRRDGIQVEKAADNIQLIVSLTSDDGRLTGVELGEYASA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 161 NMKDAISRTSGVGDVQLFGSQYAMRIWMDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
Cdd:PRK09577 160 NVLQALRRVEGVGKVQFWGAEYAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSAVPDSAPIAATVFADAPL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 241 TSADEFSKILLKVNQDGSQVRLRDVAKVELGGENYDIIAKFNGKPASGLGIKLATGANALDTANAIRDELKKMEPFFPSG 320
Cdd:PRK09577 240 KTPEDFGAIALRARADGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 321 LKIVYPYDTTPFVKISIHEVVKTLAEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAIFGFSINTLTMFGMVL 400
Cdd:PRK09577 320 VKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480
Cdd:PRK09577 400 AIGILVDDAIVVVENVERLMVEEGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGF 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 481 SVLVALILTPALCATMLKPIAKGDHgeGKKGFFGWFNRMFDKSTHHYTDSVGGILRSTGRYLALYLIIVVGMAYLFVRLP 560
Cdd:PRK09577 480 SAFLALSLTPALCATLLKPVDGDHH--EKRGFFGWFNRFVARSTQRYATRVGAILKRPLRWLVVYGALTAAAALLFTRLP 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 561 SSFLPDEDQGVFLSMAQLPAGATQERTQKVLDEMTDYYLTKEKanVESVFAVNGFGFAGRGQNTGIAFVSLKDWSERPGK 640
Cdd:PRK09577 558 TAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEP--VAYTFALGGFNLYGEGPNGGMIFVTLKDWKERKAA 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 641 ENKVEAITQRAMGAFSQIKDAMVFAFNLPAIVELGTATGFDFQLIDQAGLGHEKLTQARNQLFGEVAKHPdLLVGVRPNG 720
Cdd:PRK09577 636 RDHVQAIVARINERFAGTPNTTVFAMNSPALPDLGSTSGFDFRLQDRGGLGYAAFVAAREQLLAEGAKDP-ALTDLMFAG 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPEDIGNWYVRGSDGQMVP 800
Cdd:PRK09577 715 TQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKLRVRNAQGEMVP 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 801 FSAFSTSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMAMMEQLASKLPSGIGYDWTGMSYQERLSGNQAPALYAIS 880
Cdd:PRK09577 795 LAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAATLPAGIGYAWSGQSFEERLSGAQAPMLFALS 874
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDkEGKGL 960
Cdd:PRK09577 875 VLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVAKDLVA-QRMSL 953
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*....
gi 496059457 961 IEATLDAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAI 1019
Cdd:PRK09577 954 ADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAV 1012
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
5-1017 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 776.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 5 FIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISATYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSdS 84
Cdd:NF033617 4 FIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQS-S 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 85 TGTVQITLTFQSGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVE-KSSSSFLMVVGVinTNGTMTQEDISDYVGANMK 163
Cdd:NF033617 83 LGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVYRKaNSADTPIMYIGL--TSEEMPRGQLTDYAERVLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 164 DAISRTSGVGDVQLFGSQY-AMRIWMDPNKLNNFQLTPVDVISAIKAQNAQVAAGQlggtppVKGQQLNASIIAQTRLTS 242
Cdd:NF033617 161 PKLSQINGVGSVDVSGGQRpAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGA------VRGDSVVSTVRANDQLKT 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 243 ADEFSKILLKVNQDGSQVRLRDVAKVELGGENYDIIAKFNGKPASGLGIKLATGANALDTANAIRDELKKMEPFFPSGLK 322
Cdd:NF033617 235 AEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIK 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 323 IVYPYDTTPFVKISIHEVVKTLAEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAIFGFSINTLTMFGMVLAI 402
Cdd:NF033617 315 VNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAI 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 403 GLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSV 482
Cdd:NF033617 395 GLVVDDAIVVVENIHRHI-EEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISG 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 483 LVALILTPALCATMLKPIAKGDhgegkkGFFGWFNRMFDKSTHHYTDSVGGILRSTGRYLALYLIIVVGMAYLFVRLPSS 562
Cdd:NF033617 474 IVALTLTPMMCSRLLKANEKPG------RFARAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKE 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 563 FLPDEDQGVFLSMAQLPAGATQERTQKVLDEMTDYYLTKEKanVESVFAVNGFGfAGRGQNTGIAFVSLKDWSERpgkEN 642
Cdd:NF033617 548 LAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPE--VQSLTSFNGVG-GNPGDNTGFGIINLKPWDER---DV 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 643 KVEAITQRAMGAFSQIKDAMVFAFNLPAIvELGTATGFDFQLIDQAGLGHEKLTQARNQLFGEVAKHPdLLVGVRPNGLE 722
Cdd:NF033617 622 SAQEIIDRLRPKLAKVPGMDLFLFPLQDL-PGGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSP-QFADVDSDLQD 699
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 723 DTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPEDIGNWYVRGSDGQMVPFS 802
Cdd:NF033617 700 KGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPLS 779
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 803 AFSTSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMAMMEQLA-SKLPSGIGYDWTGMSYQERLSGNQAPALYAISL 881
Cdd:NF033617 780 TLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQAAkELLPSGISGSFQGAARAFQEEGSSLLFLFLLAL 859
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 882 IVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLI 961
Cdd:NF033617 860 AAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELQRHQGLSRR 939
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*.
gi 496059457 962 EATLDAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVL 1017
Cdd:NF033617 940 EAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLF 995
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
5-1019 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 587.19 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 5 FIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISATYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDS 84
Cdd:PRK09579 7 FIRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSRQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 85 TGTVqITLTFQSGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVinTNGTMTQEDISDYVGANMKD 164
Cdd:PRK09579 87 NFSI-ISIYARIGADSDRLFTELLAKANEVKNQLPQDAEDPVLSKEAADASALMYISF--YSEEMSNPQITDYLSRVIQP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 165 AISRTSGVGDVQLFGSQ-YAMRIWMDPNKLNNFQLTPVDVISAIKAQNAQVAAGQlggtppVKGQQLNASIIAQTRLTSA 243
Cdd:PRK09579 164 KLATLPGMAEAEILGNQvFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGE------VKGEYVVTSINASTELKSA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 244 DEFSKILLKVNQDgSQVRLRDVAKVELGGENYDIIAKFNGKPASGLGIKLATGANALDTANAIRDELKKMEPFFPSGLKI 323
Cdd:PRK09579 238 EAFAAIPVKTSGD-SRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPPNLKV 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 324 VYPYDTTPFVKISIHEVVKTLAEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAIFGFSINTLTMFGMVLAIG 403
Cdd:PRK09579 317 SIAYDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIG 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 404 LLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVL 483
Cdd:PRK09579 397 LVVDDAIVVVENIHRHI-EEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGI 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 484 VALILTPALCATMLKpiakgdHGEGKKGFFGWFNRMFDKSTHHYTDSVGGILRSTGRYLALYLIIVVGMAYLFVRLPSSF 563
Cdd:PRK09579 476 VALTLSPMMCALLLR------HEENPSGLAHRLDRLFERLKQRYQRALHGTLNTRPVVLVFAVIVLALIPVLLKFTQSEL 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 564 LPDEDQGVFLSMAQLPAGATQERTQKVLDEMTDYYltKEKANVESVFAVNGFGfagrGQNTGIAFVSLKDWSERPGKENK 643
Cdd:PRK09579 550 APEEDQGIIFMMSSSPQPANLDYLNAYTDEFTPIF--KSFPEYYSSFQINGFN----GVQSGIGGFLLKPWNERERTQME 623
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 644 VEAITQramGAFSQIKDAMVFAFNLPAIVelGTATGFDFQLIDQAGLGHEKLTQARNQLfGEVAKHPDLLVGVRPNGLED 723
Cdd:PRK09579 624 LLPLVQ---AKLEEIPGLQIFGFNLPSLP--GTGEGLPFQFVINTANDYESLLQVAQRV-KQRAQESGKFAFLDIDLAFD 697
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 724 TPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPEDIGNWYVRGSDGQMVPFSA 803
Cdd:PRK09579 698 KPEVVVDIDRAKAAQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNYYVKNEQGQLLPLST 777
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 804 FSTSRWEYGSPRLERYNGLPSMEIlgQAAPGKSTGEAMAMMEQLA-SKLPSGIGYDWTGMSYQERLSGNQAPALYAISLI 882
Cdd:PRK09579 778 LITLSDRARPRQLNQFQQLNSAII--SGFPIVSMGEAIETVQQIArEEAPEGFAFDYAGASRQYVQEGSALWVTFGLALA 855
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 883 VVFLCLAALYESWSIPFSVMLVVPLGVIGALLaATFRGLTN-DVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLI 961
Cdd:PRK09579 856 IIFLVLAAQFESFRDPLVILVTVPLSICGALI-PLFLGVSSmNIYTQVGLVTLIGLISKHGILIVEFANQLRHEQGLSRR 934
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*...
gi 496059457 962 EATLDAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAI 1019
Cdd:PRK09579 935 EAIEEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTL 992
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
4-1017 |
4.78e-136 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 436.38 E-value: 4.78e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 4 FFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISATYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSd 83
Cdd:COG3696 8 FSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVKEVRSIS- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 84 STGTVQITLTFQSGTDADIAQVQVQNKLQLAMPLLPQEVQQQ-G-VSvekSSSSFLMVVGVINTNGTMTQED---ISDYV 158
Cdd:COG3696 87 RFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPElGpIS---TGLGEIYQYTLESDPGKYSLMElrtLQDWV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 159 ganMKDAISRTSGVGDVQLFG---SQYAMRIwmDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLggtpPVKGQQLNasII 235
Cdd:COG3696 164 ---IRPQLRSVPGVAEVNSFGgfvKQYQVLV--DPAKLRAYGLTLDDVIEALERNNANVGGGYI----ERGGQEYL--VR 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 236 AQTRLTSADEFSKILLKvNQDGSQVRLRDVAKVELGGENYDIIAKFNGKPASGLGIKLA-TGANALDTANAIRDELKKME 314
Cdd:COG3696 233 GIGLIRSLEDIENIVVK-TRNGTPVLLRDVAEVRIGPAPRRGAATLNGEGEVVGGIVLMlKGENALEVIEAVKAKLAELK 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 315 PFFPSGLKIVYPYDTTPFVKISIHEVVKTLAEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAIFGFSINTLT 394
Cdd:COG3696 312 PSLPEGVKIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMS 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 395 MFGMVLAIGLLVDDAIVVVENVERVMAE-----EGLPPKEATRKSMGQIQGALV-GIAMVLsAVFIPMAFFGGSTGAIYR 468
Cdd:COG3696 392 LGGLAIDFGIIVDGAVVMVENILRRLEEnraagTPRERLEVVLEAAREVRRPIFfATLIII-LVFLPIFTLEGVEGKLFR 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 469 QFSITIVSAMALSVLVALILTPALCATMLKPiaKGDHGEgkkgffgwfNRMFDKSTHHYTDSVGGILRSTGRYLALYLII 548
Cdd:COG3696 471 PMALTVIFALLGALLLSLTLVPVLASLLLRG--KVPEKE---------NPLVRWLKRLYRPLLRWALRHPKLVLAVALVL 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 549 VVGMAYLFVRLPSSFLPDEDQGVFLSMAQLPAGATQERTQKVLDEMTDyyLTKEKANVESVfavngFGFAGR-------- 620
Cdd:COG3696 540 LVLALALFPRLGSEFLPELDEGDLLVMATLPPGISLEESVELGQQVER--ILKSFPEVESV-----VSRTGRaedatdpm 612
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 621 GQNTGIAFVSLKDWSERPGKENKvEAITQRAMGAFSQIKdAMVFAFNLP---AIVEL--GTAT-------GFDFQLIDQA 688
Cdd:COG3696 613 GVNMSETFVILKPRSEWRSGRTK-EELIAEMREALEQIP-GVNFNFSQPiqmRVDELlsGVRAdvavkifGDDLDVLRRL 690
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 689 GlghekltqarNQLFGEVAKHP---DLLVgVRPNGLedtPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDR 765
Cdd:COG3696 691 A----------EQIEAVLKTVPgaaDVQV-ERVTGL---PQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEG 756
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 766 GRVKKVYVMSEAKYRMLPEDIGNWYVRGSDGQMVPFSAFSTSRWEYGSPRLERYNGLPSMEI--------LGQAApgkst 837
Cdd:COG3696 757 ERRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLSQVADIEVVEGPNQISRENGRRRIVVqanvrgrdLGSFV----- 831
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 838 GEAMAMMEQlASKLPSGIGYDWTGM-----SYQERLSgnqapALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGA 912
Cdd:COG3696 832 AEAQAKVAE-QVKLPPGYYIEWGGQfenlqRATARLA-----IVVPLALLLIFLLLYLAFGSVRDALLILLNVPFALIGG 905
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 913 LLAATFRGLtndvYFQ----VGLLTTIGLSAKNAILIVEFAKDLMdKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMP 988
Cdd:COG3696 906 VLALWLRGM----PLSvsagVGFIALFGVAVLNGVVLVSYINQLR-AEGLDLREAIIEGALERLRPVLMTALVAALGLLP 980
|
1050 1060
....*....|....*....|....*....
gi 496059457 989 LVISSGAGSGAQNAVGTGVMGGMVTATVL 1017
Cdd:COG3696 981 MALSTGPGSEVQRPLATVVIGGLITSTLL 1009
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
5-1017 |
2.24e-126 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 410.66 E-value: 2.24e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 5 FIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISATYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSdS 84
Cdd:PRK10614 7 FIYRPVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSS-S 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 85 TGTVQITLTFQSGTDADIAQVQVQNKLQLAMPLLPQEVQQQGvSVEKSSSSFLMVVGVINTNGTMTQEDISDYVGANMKD 164
Cdd:PRK10614 86 LGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRP-TYRKANPSDAPIMILTLTSDTYSQGQLYDFASTQLAQ 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 165 AISRTSGVGDVQLFGSQY-AMRIWMDPNKLNNFQLTPVDVISAIKAQNAQVAAGQlggtppVKGQQLNASIIAQTRLTSA 243
Cdd:PRK10614 165 TISQIDGVGDVDVGGSSLpAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGA------VEDGTHRWQIQTNDELKTA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 244 DEFSKILLKVNQdGSQVRLRDVAKVELGGENYDIIAKFNGKPASGLGIKLATGANALDTANAIRDELKKMEPFFPSGLKI 323
Cdd:PRK10614 239 AEYQPLIIHYNN-GAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETIPAAIDL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 324 VYPYDTTPFVKISIHEVVKTLAEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAIFGFSINTLTMFGMVLAIG 403
Cdd:PRK10614 318 QIAQDRSPTIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATG 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 404 LLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVL 483
Cdd:PRK10614 398 FVVDDAIVVLENISRHL-EAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVTLSVAIGISLL 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 484 VALILTPALCATMLKPIAKGDHGEgKKGffgwFNRMFDKSTHHYTDSVGGILRSTgRYLALYLIIVVGM-AYLFVRLPSS 562
Cdd:PRK10614 477 VSLTLTPMMCAWLLKSSKPREQKR-LRG----FGRMLVALQQGYGRSLKWVLNHT-RWVGVVLLGTIALnVWLYISIPKT 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 563 FLPDEDQGVFLSMAQLPAGAT-QERTQKVLDEMTdyyLTKEKANVESVfavngFGFAGRGQ-NTGIAFVSLKDWSERpgK 640
Cdd:PRK10614 551 FFPEQDTGRLMGFIQADQSISfQAMRGKLQDFMK---IIRDDPAVDNV-----TGFTGGSRvNSGMMFITLKPLSER--S 620
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 641 ENKVEAITqRAMGAFSQIKDAMVFafnLPAIVEL-----GTATGFDFQLI--DQAGLGH--EKLTQArnqlfgeVAKHPD 711
Cdd:PRK10614 621 ETAQQVID-RLRVKLAKEPGANLF---LMAVQDIrvggrQSNASYQYTLLsdDLAALREwePKIRKA-------LAALPE 689
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 712 lLVGVRPNGLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPEDIGNWYV 791
Cdd:PRK10614 690 -LADVNSDQQDKGAEMALTYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYTQDISALEKMFV 768
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 792 RGSDGQMVPFSAFstSRWE-YGSPRLERYNGLPSMEILG-QAAPGKSTGEAMAMMEQLASKL--PSGI--GYDWTGMSYQ 865
Cdd:PRK10614 769 INNEGKAIPLSYF--AKWQpANAPLSVNHQGLSAASTISfNLPTGKSLSDASAAIERAMTQLgvPSTVrgSFAGTAQVFQ 846
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 866 ERLSGNQAPALYAIslIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILI 945
Cdd:PRK10614 847 ETMNSQLILILAAI--ATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMM 924
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 496059457 946 VEFAKDLMDKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVL 1017
Cdd:PRK10614 925 VDFALEAQRNGNLTAQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVGGLVMSQLL 996
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
5-1019 |
5.10e-119 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 391.02 E-value: 5.10e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 5 FIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISATYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSdS 84
Cdd:PRK10503 16 FILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQS-S 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 85 TGTVQITLTFQSGTDADIAQVQVQNKLQLAMPLLPQEVQQQGV-SVEKSSSSFLMVVGVINTNGTMTQedISDYVGANMK 163
Cdd:PRK10503 95 GGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVySKVNPADPPIMTLAVTSTAMPMTQ--VEDMVETRVA 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 164 DAISRTSGVGDVQLFGSQY-AMRIWMDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLGGtpPVKGQQLNASiiaqTRLTS 242
Cdd:PRK10503 173 QKISQVSGVGLVTLSGGQRpAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDG--PTRAVTLSAN----DQMQS 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 243 ADEFSKILLKVnQDGSQVRLRDVAKVELGGENYDIIAKFNGKPASGLGIKLATGANALDTANAIRDELKKMEPFFPSGLK 322
Cdd:PRK10503 247 AEEYRQLIIAY-QNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSVK 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 323 IVYPYDTTPFVKISIHEVVKTLAEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAIFGFSINTLTMFGMVLAI 402
Cdd:PRK10503 326 VTVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIAT 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 403 GLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSV 482
Cdd:PRK10503 406 GFVVDDAIVVIENISRYI-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILISA 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 483 LVALILTPALCATMLKPIAKGDHGEgkkgFFGWFNRMFDKSTHHYTDSVGGILRSTGRYLALYLIIVVGMAYLFVRLPSS 562
Cdd:PRK10503 485 VVSLTLTPMMCARMLSQESLRKQNR----FSRASERMFDRVIAAYGRGLAKVLNHPWLTLSVALSTLLLTVLLWIFIPKG 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 563 FLPDEDQGVFLSMAQLPA----GATQERTQKVLDEmtdyyLTKEKAnVESVFAVNGFGFAGRGQNTGIAFVSLKDWSERp 638
Cdd:PRK10503 561 FFPVQDNGIIQGTLQAPQsssfANMAQRQRQVADV-----ILQDPA-VQSLTSFVGVDGTNPSLNSARLQINLKPLDER- 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 639 gkENKVEAITQRAMGAFSQIKDAMVFafnLPAIVEL---GTATGFDFQLIDQAGlGHEKLTQARNQLFGEVAKHPDlLVG 715
Cdd:PRK10503 634 --DDRVQKVIARLQTAVAKVPGVDLY---LQPTQDLtidTQVSRTQYQFTLQAT-SLDALSTWVPKLMEKLQQLPQ-LSD 706
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 716 VRPNGLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPEDIGNWYVRGSD 795
Cdd:PRK10503 707 VSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSD 786
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 796 GQMVPFSAFSTSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMAMMEQLASKL--PSGIGYDWTG--MSYQERLSGN 871
Cdd:PRK10503 787 GGVVPLSSIATIEQRFGPLSINHLDQFPSTTISFNVPDGYSLGDAVQAIMDTEKTLnlPADITTQFQGstLAFQSALGST 866
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 872 QAPALYAIslIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKD 951
Cdd:PRK10503 867 VWLIVAAV--VAMYIVLGVLYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALA 944
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 496059457 952 LMDKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAI 1019
Cdd:PRK10503 945 AEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGLIVSQVLTL 1012
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
17-1019 |
6.77e-80 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 282.81 E-value: 6.77e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 17 IIIMLAGGLAIL------KLPVAQYPTIAPPAVTISATYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSdSTGTVQI 90
Cdd:TIGR00914 15 LVLLATLVMAILgiwsynRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTRSLS-RYGLSQV 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 91 TLTFQSGTDADIAQVQVQNKLQLAMPLLPQEVQQQ------GV------SVEKSSSSFLMVVGVINTNGTMTqedISDYV 158
Cdd:TIGR00914 94 TVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEmgpistGLgeiflyTVEAEEGARKKDGGAYTLTDLRT---IQDWI 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 159 ganMKDAISRTSGVGDVQLFG---SQYAMRIwmDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLggtpPVKGQQLnaSII 235
Cdd:TIGR00914 171 ---IRPQLRTVPGVAEVNSIGgyvKQFLVAP--DPEKLAAYGLSLADVVNALERNNQNVGAGYI----ERRGEQY--LVR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 236 AQTRLTSADEFSKILLKvNQDGSQVRLRDVAKVELGGENYDIIAKFNGKPASGLGIKLATGANALDTANAIRDELKKMEP 315
Cdd:TIGR00914 240 APGQVQSMDDIRNIVIA-TGEGVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKLETINK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 316 FFPSGLKIVYPYDTTPFVKISIHEVVKTLAEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAIFGFSINTLTM 395
Cdd:TIGR00914 319 TLPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSL 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 396 fgMVLAIGLLVDDAIVVVENVERVMAE----EGLPPKEATR-----KSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAI 466
Cdd:TIGR00914 399 --GALDFGLIVDGAVVIVENAHRRLAEaqhhHGRQLTLKERlhevfAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKM 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 467 YRQFSITIVSAMALSVLVALILTPALCATML-KPIAKGDHgegkkgffgWFNRMFDKSTHHYTDSVggiLRSTGRYLALY 545
Cdd:TIGR00914 477 FHPMAFTVVLALAGAMILSLTFVPAAVALFIrGKVAEKEN---------RLMRVLKRRYEPLLERV---LAWPAVVLGAA 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 546 LIIVVGMAYLFVRLPSSFLPDEDQGVFLSMAQLPAGATqertqkvLDEMTDYYLTKEKAnVESVFAVNG-FGFAGRGQ-- 622
Cdd:TIGR00914 545 AVSIVLVVWIASRVGGEFIPSLNEGDLAYQALRIPGTS-------LAQSVAMQQTLEKL-IKSFPEVARvFAKTGTAEia 616
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 623 ------NTGIAFVSLKDWSE-RPGKENKVEAI------TQRAMGAFSQIKDAMVFAFNlpaivELGTAT---------GF 680
Cdd:TIGR00914 617 tdpmppNASDTYIILKPESQwPEGKKTKEDLIeeiqeaTVRIPGNNYEFTQPIQMRFN-----ELISGVrsdvavkvfGD 691
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 681 DFQLIDqaglghekltqARNQLFGEVAKHPDLLVGVRPNGLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVN 760
Cdd:TIGR00914 692 DLDDLD-----------ATAEKISAVLKGVPGAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSG 760
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 761 DFIDRGRVKKVYVMSEAKYRMLPEDIGNWYV-----RGSDGQMVPFSAFSTSRWEYGSPRLERYNGLPSMEILGQAApGK 835
Cdd:TIGR00914 761 ETFEGDRRFDIVIRLPESLRESPQALRQLPIplplsEDARKQFIPLSDVADLRVSPGPNQISRENGKRRVVVSANVR-GR 839
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 836 STGE-----AMAMMEQLasKLPSGIGYDWTGmSYQERLSGNQAPALYA-ISLIVVFLCLAALYESWSIPFSVMLVVPLGV 909
Cdd:TIGR00914 840 DLGSfvddaKKAIAEQV--KLPPGYWITWGG-QFEQLQSATKRLQIVVpVTLLLIFVLLYAAFGNVKDALLVFTGIPFAL 916
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 910 IGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDkEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPL 989
Cdd:TIGR00914 917 TGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISFIRKLLE-EGPSLDEAVYEGALTRVRPVLMTALVASLGFVPM 995
|
1050 1060 1070
....*....|....*....|....*....|
gi 496059457 990 VISSGAGSGAQNAVGTGVMGGMVTATVLAI 1019
Cdd:TIGR00914 996 AIATGTGAEVQRPLATVVIGGIITATLLTL 1025
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
277-1018 |
1.41e-21 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 101.09 E-value: 1.41e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 277 IIAKFNGKPASGLgiklatgANALDTANAIRDELKKMEPffpSGLKIVY---PYDTTPFVKISIHEVVKTLAEAIILVFL 353
Cdd:COG1033 164 IVVTLDPDPLSSD-------LDRKEVVAEIRAIIAKYED---PGVEVYLtgfPVLRGDIAEAIQSDLAIFFPLALLLILL 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 354 VMYLFLQNFRATLIPTIAVPVVLLGTFAVLAIFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAeEGLPPKEATRK 433
Cdd:COG1033 234 LLFLFFRSLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREERR-KGLDKREALRE 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 434 SMGQiqgalVGIAMVLSAV-----FIPMAFfggSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEG 508
Cdd:COG1033 313 ALRK-----LGPPVLLTSLttaigFLSLLF---SDIPPIRDFGIVAAIGVLLAFLTSLTLLPALLSLLPRPKPKTRRLKK 384
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 509 KKGFFGWFNRMFDKSTHHYTdsvggilrstgRYLALYLIIVVGMAYLFVRLPSSFLPDEDqgvflsmaqlpagatqertq 588
Cdd:COG1033 385 PPELGRLLAKLARFVLRRPK-----------VILVVALVLAVVSLYGISRLKVEYDFEDY-------------------- 433
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 589 kvLDEMTDYYLTKEKanVESVFAvngfgfagrgqNTGIAFVSLKdwSERPGKENKVEAItqRAMGAFSQikdamvfafNL 668
Cdd:COG1033 434 --LPEDSPIRQDLDF--IEENFG-----------GSDPLEVVVD--TGEPDGLKDPEVL--KEIDRLQD---------YL 485
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 669 PAIVELGTATGFDfQLIDQAglghekltqarNQLFGEvakhpdllvgvrpnglEDTPQFKIDIDQEKAQALGVSISDInt 748
Cdd:COG1033 486 ESLPEVGKVLSLA-DLVKEL-----------NQALNE----------------GDPKYYALPESRELLAQLLLLLSSP-- 535
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 749 tlgaawGGSYVNDFIDrgrvkkvyvmseakyrmlpedignwyvrgSDGQMVPFSAfstsrweygsprleRYNGLPSMEIL 828
Cdd:COG1033 536 ------PGDDLSRFVD-----------------------------EDYSAARVTV--------------RLKDLDSEEIK 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 829 gqaapgkstgEAMAMMEQLASKLPSGIGYDW--TGMSY-----QERLSGNQAPALyAISLIVVFLCLAALYESWSIPFSV 901
Cdd:COG1033 567 ----------ALVEEVRAFLAENFPPDGVEVtlTGSAVlfaaiNESVIESQIRSL-LLALLLIFLLLLLAFRSLRLGLIS 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 902 ML--VVPLGVIGALLAATfrgltnDVYFQVGLLT----TIGLSAKNAILIVEFAKDLMdKEGKGLIEATLDAVRMRLRPI 975
Cdd:COG1033 636 LIpnLLPILLTFGLMGLL------GIPLNIATAVvasiALGIGVDYTIHFLSRYREER-RKGGDLEEAIRRALRTTGKAI 708
|
730 740 750 760
....*....|....*....|....*....|....*....|...
gi 496059457 976 LMTSLAFILGVMPLVISSGagsgaqnaVGTGVMGGMVTATVLA 1018
Cdd:COG1033 709 LFTSLTLAAGFGVLLFSSF--------PPLADFGLLLALGLLV 743
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
291-502 |
1.68e-18 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 91.07 E-value: 1.68e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 291 IKLATGANALDTANAIRDELKKMEP-----FFPSGLKIVYpYDTTPFVkisIHEVVKTLAEAIILVFLVMYLFLQNFRAT 365
Cdd:COG1033 557 LKDLDSEEIKALVEEVRAFLAENFPpdgveVTLTGSAVLF-AAINESV---IESQIRSLLLALLLIFLLLLLAFRSLRLG 632
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 366 LIPTIAVPVVLLGTFAVLAIFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGI 445
Cdd:COG1033 633 LISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREER-RKGGDLEEAIRRALRTTGKAILFT 711
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 496059457 446 AMVLSAVFIPMAFfggSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAK 502
Cdd:COG1033 712 SLTLAAGFGVLLF---SSFPPLADFGLLLALGLLVALLAALLLLPALLLLLDPRIAK 765
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
289-593 |
5.64e-10 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 63.25 E-value: 5.64e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 289 LGIKLATGANALDTANAIRDELKKMEPffpSGLKIVY---PYDTTPFVKISIHEVVKTLAEAIILVFLVMYLFLQNFRAT 365
Cdd:COG2409 120 VTLDGDAGDEAAEAVDALRDAVAAAPA---PGLTVYVtgpAALAADLNEAFEEDLGRAELITLPVALVVLLLVFRSLVAA 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 366 LIPTIAVPVVLLGTFAVLAIFG--FSINTLT-MFGMVLAIGLLVDDAIVVV----ENVERvmaeeGLPPKEATRKSMGQI 438
Cdd:COG2409 197 LLPLLTAGLAVGVALGLLALLAafTDVSSFApNLLTMLGLGVGIDYALFLVsryrEELRA-----GEDREEAVARAVATA 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 439 Q------GALVGIAMvLSAVFIPMAFFggstgaiyRQFSITIVSAMALSVLVALILTPALCATM------LKPIAKGDHG 506
Cdd:COG2409 272 GravlfsGLTVAIAL-LGLLLAGLPFL--------RSMGPAAAIGVAVAVLAALTLLPALLALLgrrvfwPRRPRRRRAA 342
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 507 EGKKGFFGWFnrmfdksthhytdsVGGILRSTGRYLALYLIIVVGMAYLFVRLPSSFlPDEDqgvflsmaQLPAGATQER 586
Cdd:COG2409 343 APESGFWRRL--------------ARAVVRRPVPVLVAAVAVLLALALPALGLRLGL-PDAD--------SLPADSPSRQ 399
|
....*..
gi 496059457 587 TQKVLDE 593
Cdd:COG2409 400 GYDALAE 406
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
299-494 |
1.12e-09 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 61.15 E-value: 1.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 299 ALDTANAIRDELKKMEPffPSGLKIvypYDTTP------FVKISIHEVVKTLAEAIILVFLVMYLFLQNFRATLIPTIAV 372
Cdd:pfam03176 102 ADESVAAVRDAVEQAPP--PEGLKA---YLTGPaatvadLRDAGDRDLGLIEAVTLVVIFIILLIVYRSVVAALLPLLTV 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 373 PVVLLGTFAVLAIF----GFSINTLT-MFGMVLAIGLLVDDAIVVvenVERVMAE--EGLPPKEATRKSMGQIQGALVGI 445
Cdd:pfam03176 177 GLSLGAAQGLVAILahilGIGLSTFAlNLLVVLLIAVGTDYALFL---VSRYREElrAGEDREEAVIRAVRGTGKVVTAA 253
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 496059457 446 AMVLSAVFIPMAFfggSTGAIYRQFSITIVSAMALSVLVALILTPALCA 494
Cdd:pfam03176 254 GLTVAIAMLALSF---ARLPVFAQVGPTIAIGVLVDVLAALTLLPALLA 299
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
158-492 |
1.18e-08 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 59.27 E-value: 1.18e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 158 VGANMKDAISRTSGVGDVQLF--GSQYAMRIWMDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLggtppVKGQQ---LNA 232
Cdd:COG3696 690 LAEQIEAVLKTVPGAADVQVErvTGLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQV-----YEGERrfdIVV 764
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 233 SIIAQTRlTSADEFSKILLKVnQDGSQVRLRDVAKVELG-GENYdiIAKFNGKPasglgiKLATGANALDTA-------- 303
Cdd:COG3696 765 RLPEELR-DDPEAIRNLPIPT-PSGAQVPLSQVADIEVVeGPNQ--ISRENGRR------RIVVQANVRGRDlgsfvaea 834
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 304 -NAIRDELKkmepfFPSG------------------LKIVYPYdttpfvkisihevvktlaeAIILVFLVMYLFLQNFRA 364
Cdd:COG3696 835 qAKVAEQVK-----LPPGyyiewggqfenlqratarLAIVVPL-------------------ALLLIFLLLYLAFGSVRD 890
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 365 TLIPTIAVPVVLLGTFAVLAIFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMaEEGLPPKEATrksmgqIQGALVG 444
Cdd:COG3696 891 ALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLR-AEGLDLREAI------IEGALER 963
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 496059457 445 I------AMVLSAVFIPMAfFGGSTGA-IYRQFSITIVSAMALSVLVALILTPAL 492
Cdd:COG3696 964 LrpvlmtALVAALGLLPMA-LSTGPGSeVQRPLATVVIGGLITSTLLTLLVLPAL 1017
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
249-503 |
1.07e-07 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 56.31 E-value: 1.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 249 ILLKVNQDG--SQVRLRDVAKVELGgENYDIIAKFNGKPASGLGIKLA---TGANALDTANAIRDELKkmepfFPSGLKI 323
Cdd:TIGR00914 791 IPLPLSEDArkQFIPLSDVADLRVS-PGPNQISRENGKRRVVVSANVRgrdLGSFVDDAKKAIAEQVK-----LPPGYWI 864
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 324 VYPyDTTPFVKISIHEVVKTLAEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAIFGFSINTLTMFGMVLAIG 403
Cdd:TIGR00914 865 TWG-GQFEQLQSATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSG 943
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 404 LLVDDAIVVVENVeRVMAEEGLPPKEATrksmgqIQGALVGI------AMVLSAVFIPMAFFGGSTGAIYRQFSITIVSA 477
Cdd:TIGR00914 944 VAVLNGLVMISFI-RKLLEEGPSLDEAV------YEGALTRVrpvlmtALVASLGFVPMAIATGTGAEVQRPLATVVIGG 1016
|
250 260
....*....|....*....|....*.
gi 496059457 478 MALSVLVALILTPALCATMLKPIAKG 503
Cdd:TIGR00914 1017 IITATLLTLFVLPALYRLVHRRRHKG 1042
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
301-492 |
8.93e-07 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 52.92 E-value: 8.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 301 DTANAIRDELKKMEPffPSGLKIVY---PYDTTPFVKISIHEVVKTLAEAIILVFLVMYLFLQNFRATLIPtiaVPVVLL 377
Cdd:TIGR00921 155 PIYNDVERSLERTNP--PSGKFLDVtgsPAINYDIEREFGKDMGTTMAISGILVVLVLLLDFKRWWRPLLP---LVIILF 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 378 GTFAVLAIFG-----FSINTLTMFGMVLAIGLlvdDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAV 452
Cdd:TIGR00921 230 GVAWVLGIMGwlgipLYATTLLAVPMLIGVGI---DYGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVLIALLTTSAG 306
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 496059457 453 FIPMAFfggSTGAIYRQFSITIVSAMALSVLVALILTPAL 492
Cdd:TIGR00921 307 FAALAL---SEFPMVSEFGLGLVAGLITAYLLTLLVLPAL 343
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
269-492 |
9.38e-07 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 52.29 E-value: 9.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 269 ELGGENYDIIAKFNGKPASGLGIKLATGAnaldtanairdelkkmepfFPSGLKIVYPYDTTP-FVKISIHEVVKTLAEA 347
Cdd:TIGR01129 197 AITGGSGQITGNFTAEEANDLALVLRSGA-------------------LPAPLQILEERTIGPsLGADSIEAGIKAGLIG 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 348 IILVFLVMYLFLQNFraTLIPTIAVPVVLLGTFAVLAIFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAeEGLPP 427
Cdd:TIGR01129 258 LVLVLVFMILYYRLF--GLIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVDANVLIYERIKEELR-LGKSV 334
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 496059457 428 KEAT----RKSMGQIQGAlvGIAMVLSAVFipMAFFGgsTGAIyRQFSITIVSAMALSVLVALILTPAL 492
Cdd:TIGR01129 335 RQAIeagfERAFSTIFDA--NITTLIAALI--LYVFG--TGPV-KGFAVTLAIGIIASLFTALVFTRLL 396
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
338-491 |
3.43e-06 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 51.01 E-value: 3.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 338 HEVVKTLAEAIILVFLVMYLFLQNFRATLIpTIAVPVV-LLGTFAVLAIFGFSINTLTMFGMVLAIGLLVDDAIvvvenv 416
Cdd:COG4258 639 NDALWLLLLALLLILLLLLLRLRSLRRALR-VLLPPLLaVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYAL------ 711
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 496059457 417 erVMAEEGLPPKEATRksmgqiqgALVGIAM-VLSAV--FIPMAFfgGSTGAIyRQFSITIVSAMALSVLVALILTPA 491
Cdd:COG4258 712 --FFTEGLLDKGELAR--------TLLSILLaALTTLlgFGLLAF--SSTPAL-RSFGLTVLLGILLALLLAPLLAPR 776
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
336-492 |
7.65e-06 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 49.73 E-value: 7.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 336 SIHEVVKTLAEAIILVFLVMYLFLQNFRatLIPTIAVPVVLLGTFAVLAIFGFsinTLTM---FGMVLAIGLLVDDaivv 412
Cdd:COG0342 269 SIEKGLIAGLIGLLLVALFMLLYYRLPG--LVANIALALNVVLLLGVLSLLGA---TLTLpgiAGIILTIGMAVDA---- 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 413 veNV---ERVMAE--EGLPPKEAT----RKSMGQIQGALV--GIAMVlsavfiPMAFFGgsTGAIyRQFSITIVSAMALS 481
Cdd:COG0342 340 --NVlifERIREElrAGRSLRAAIeagfKRAFSTILDANVttLIAAV------VLFVLG--TGPV-KGFAVTLILGILIS 408
|
170
....*....|.
gi 496059457 482 VLVALILTPAL 492
Cdd:COG0342 409 MFTAVPVTRPL 419
|
|
| Patched |
pfam02460 |
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic ... |
341-492 |
7.13e-05 |
|
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic Hedgehog. This protein associates with the smoothened protein to transduce hedgehog signals.
Pssm-ID: 308203 [Multi-domain] Cd Length: 793 Bit Score: 46.96 E-value: 7.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 341 VKTLAEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAIFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERvm 420
Cdd:pfam02460 642 IQNIVITLICMFIVCFLFIPNPPCVFVITLAIASIDIGVFGFLSLWGVDLDPISMITIIMSIGFSVDFSAHIAYHFVR-- 719
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 496059457 421 aEEGLPPKEATRKSMGQI-----QGALVGIAMVLSAVFIPmaffggsTGAIyRQFSITIVSAMALSVLVALILTPAL 492
Cdd:pfam02460 720 -SRGDTPAERVVDALEALgwpvfQGGLSTILGVLVLLFVP-------SYMV-VVFFKTVFLVVAIGLLHGLFILPII 787
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
336-486 |
2.24e-04 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 43.40 E-value: 2.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 336 SIHEVVKTLAEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLgTFAVLAIFGFSINTLTMFGMVLAIGLLVDDAIVVVEN 415
Cdd:TIGR00916 45 LIKAGIIALLIGLVLVLLYMLLRYEWRGAIAAIAALVHDVIL-ILGVLSLFGATLTLPGIAGLLTIIGYSVDDTVVIFDR 123
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 496059457 416 V-ERVMAEEGLPPKEATRKSmgqIQGALVGIAMVLSAVFIPMA---FFGGstGAIyRQFSITIVSAMALSVLVAL 486
Cdd:TIGR00916 124 IrEELRKYKGRTFREAINLG---INQTLSRIIDTNVTTLLAVLalyVFGG--GAI-KGFALTLGIGVIAGTYSSI 192
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
286-490 |
2.36e-04 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 45.49 E-value: 2.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 286 ASGLGIKLATGANALDTANAIRDELKKMEpfFPSGLKIVYPYDTTPFVKISIHEVVKTLAeAIILVFLVMYLFLQNFRAT 365
Cdd:PRK10614 801 ASTISFNLPTGKSLSDASAAIERAMTQLG--VPSTVRGSFAGTAQVFQETMNSQLILILA-AIATVYIVLGILYESYVHP 877
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 366 LIPTIAVPVVLLGTFAVLAIFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATrksmgqIQGALV-- 443
Cdd:PRK10614 878 LTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRNGNLTAQEAI------FQACLLrf 951
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 496059457 444 -GIAMV-LSAVF--IPMAFFGGStGAIYRQ-FSITIVSAMALSVLVALILTP 490
Cdd:PRK10614 952 rPIMMTtLAALFgaLPLVLSGGD-GAELRQpLGITIVGGLVMSQLLTLYTTP 1002
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
347-489 |
1.18e-03 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 42.91 E-value: 1.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 347 AIILVFLVMYLFLQnfRATLIPTIAVPVVLLGTFAVLAIFGFsinTLTM---FGMVLAIGLLVDDAIVVVENVErvmaEE 423
Cdd:PRK13024 275 GFALIFLFMLVYYG--LPGLIANIALLLYIFLTLGALSSLGA---VLTLpgiAGLVLGIGMAVDANVLIFERIK----EE 345
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 496059457 424 ---GLPPKEATRKSMgqiQGALVGIA-----MVLSAV--FipmaFFGgsTGAIyRQFSITIVSAMALSVLVALILT 489
Cdd:PRK13024 346 lrkGKSLKKAFKKGF---KNAFSTILdsnitTLIAAAilF----FFG--TGPV-KGFATTLIIGILASLFTAVFLT 411
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
189-487 |
1.61e-03 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 42.46 E-value: 1.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 189 DPN-KLNNFQLTPVDVISAIKAQNAQVAAGQLGGTPPVkGQQLNASIIAQTRLTSADEFSKILL-KVNqdgsqvrlrdva 266
Cdd:NF037998 308 DPNsKTEDFNGTKGKYIDPLKLYLSQNATPQLMKIDEV-FKVLNGLILSFNDKTTTSNFNQYLDeKIK------------ 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 267 kvelggeNYDIIAKFNGKPASGLGIKLATGANALDTANAIRDELKKMEPFF---PSGLKIV------YPYDTTPFVKISI 337
Cdd:NF037998 375 -------NYILNNDTINGTKTGAGAGSNTNSNQLIVATSTETIARTIEALInqtTSGFTFKvngiseFNPVVTLLMLIAS 447
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 338 HEVVKTLAEAIILVFLVMYLFLQNFraTLIptIAVPVVLLgTFAVLAIFGFSINTLTMFGMVLAIGLLVDDAIVVVENVE 417
Cdd:NF037998 448 IIFLLILAIAIMIYLLFAYRLLGLF--AII--IALTSISL-TLYSPTWFGLAIGPESITAIFIAIGLVLESCSLLFEAFK 522
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 496059457 418 RVMAEEGLPPKEATRKSMGQIQGALVGIAMVLsavFIP-MAFFGGSTGAIyRQFSITIVSAMALSVLVALI 487
Cdd:NF037998 523 KHLYKNKRSIEESFKIANKETIGIIVDALVVL---LIPnLSLFWIGSNSI-KSFATILLVGVIISLVLVII 589
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
347-565 |
6.87e-03 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 40.37 E-value: 6.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 347 AIILVFLVMYLFLQNFR---ATLIPTIavpVVLLGTFAVLAIFGFSINTLTMFGMVLAIGLLVDDAIVVVENVeRVMAEE 423
Cdd:TIGR03480 278 SFVLVLVLLWLALRSPRlvfAVLVTLI---VGLILTAAFATLAVGHLNLISVAFAVLFIGLGVDFAIQFSLRY-REERFR 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 424 GLPPKEATRKSMGQIQGALVgIAMVLSAV----FIPMAFFGGStgaiyrQFSITIVSAMALSVLVALILTPALCaTMLKP 499
Cdd:TIGR03480 354 GGNHREALSVAARRMGAALL-LAALATAAgffaFLPTDYKGVS------ELGIIAGTGMFIALFVTLTVLPALL-RLLRP 425
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 496059457 500 IAKgDHGEGKKgffgwFNRMFDKSTHHYTDSVggilrstgryLALYLIIVVGMAYLFVRLPSSFLP 565
Cdd:TIGR03480 426 PRR-RKPPGYA-----TLAPLDAFLRRHRRPV----------LGVTLILGIAALALLPQLRFDFNP 475
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
849-1019 |
7.72e-03 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 40.21 E-value: 7.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 849 SKLPSGIGYDWTG---MSYQ-ERLSGNQAPALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTND 924
Cdd:TIGR00921 167 TNPPSGKFLDVTGspaINYDiEREFGKDMGTTMAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLY 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 925 VYFQVGLLTTIGLsaknAILIVEFAKDLMDKE---GKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISsgaGSGAQN 1001
Cdd:TIGR00921 247 ATTLLAVPMLIGV----GIDYGIQTLNRYEEErdiGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALALS---EFPMVS 319
|
170
....*....|....*...
gi 496059457 1002 AVGTGVMGGMVTATVLAI 1019
Cdd:TIGR00921 320 EFGLGLVAGLITAYLLTL 337
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
338-493 |
8.16e-03 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 40.22 E-value: 8.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 338 HEVVKTLAEAIILVFLVMYLFLQNFRATLIptIAVPV---VLLGTFAVLAIFGfSINTLTM-FGMVLaIGLLVDDAIvvv 413
Cdd:COG4258 249 HDISTIGLISLLGILLLLLLVFRSLRPLLL--GLLPVavgALAGLAAVSLVFG-SVHGITLgFGSSL-IGVAVDYSL--- 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059457 414 enveRVMAEEGLPPKEATRKSMGQIQGALvGIAMVLSAV-FIPMAfFGGSTGaiYRQ---FSITIVSAMALSVLVALilt 489
Cdd:COG4258 322 ----HYLTHRRAAGEWDPRAALRRIWPTL-LLGLLTTVLgYLALL-FSPFPG--LRQlgvFAAAGLLAAALTTLLWL--- 390
|
....
gi 496059457 490 PALC 493
Cdd:COG4258 391 PLLL 394
|
|
| |
