|
Name |
Accession |
Description |
Interval |
E-value |
| APP |
cd01085 |
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline ... |
310-536 |
9.42e-106 |
|
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.
:
Pssm-ID: 238518 [Multi-domain] Cd Length: 224 Bit Score: 317.97 E-value: 9.42e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 310 NNRKAHIKDAIAMCKFMYWLKAKIGKE-TITEISASAYLETLRKEQ-GCFDISFDTISAYKEHAAMMHYSANEETNAELK 387
Cdd:cd01085 1 GMRAAHIRDGVALVEFLAWLEQEVPKGeTITELSAADKLEEFRRQQkGYVGLSFDTISGFGPNGAIVHYSPTEESNRKIS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 388 PEGMLLVDSGAQYLEGTTDITRTFVLGAISDEIKHHFTTALRSHIALSKAHFLYGCRGLNLDILARGPLWDLALDYKCGT 467
Cdd:cd01085 81 PDGLYLIDSGGQYLDGTTDITRTVHLGEPTAEQKRDYTLVLKGHIALARAKFPKGTTGSQLDALARQPLWKAGLDYGHGT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 495965160 468 GHGVGHVLNVHEGPNGFRwrivpERNDSCVLEEGMTQSNEPGVYVEGSHGIRHENEMVVCKGEKNEYGQ 536
Cdd:cd01085 161 GHGVGSFLNVHEGPQSIS-----PAPNNVPLKAGMILSNEPGYYKEGKYGIRIENLVLVVEAETTEFGG 224
|
|
| Creatinase_N_2 |
pfam16189 |
Creatinase/Prolidase N-terminal domain; |
149-307 |
6.91e-72 |
|
Creatinase/Prolidase N-terminal domain;
:
Pssm-ID: 465053 Cd Length: 159 Bit Score: 227.76 E-value: 6.91e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 149 DRPALPKKKGFFLEECYSGESTKEKLKRIRAVLKQEKATHHIVTSLDDIAWILNMRGWDIAHFPVMLSYLIIDENSASLY 228
Cdd:pfam16189 1 DRPALPANPVFVLPLKYAGESAAEKLARLREALKEKGADALVLSALDEIAWLLNLRGSDVPYNPVFLSYALVTDDEATLF 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 495965160 229 INESKLDDQLRDNLQENAIVICPYDAIYEDVKKIAQDAVVLLDKTIVNYAITSGLHKEITVINRPNPSQLMKAMKNPIE 307
Cdd:pfam16189 81 VDPEKLSDEVRAHLEENGVEIRPYDDIYEDLAALAAGKKVLLDPSRTSYALYSALPAGAKVVEAPSPITLMKAVKNETE 159
|
|
| Peptidase_M24_C |
pfam16188 |
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of ... |
536-596 |
3.77e-29 |
|
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of metallo-peptidases of the M24 family.
:
Pssm-ID: 465052 Cd Length: 63 Bit Score: 109.81 E-value: 3.77e-29
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 495965160 536 QFMYFETITFVPFDLDGIDASLLTQYEKAWLNAYHQEVYEKISPYLKEEEQ--SWLREATRAI 596
Cdd:pfam16188 1 PFLGFETLTLVPIDRKLIDVSLLTEEEIEWLNAYHARVREKLSPLLEEEEDalEWLKRATRPI 63
|
|
| Creatinase_N |
pfam01321 |
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic ... |
7-129 |
1.49e-10 |
|
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic domains from creatinase and prolidase. The exact function of this domain is uncertain.
:
Pssm-ID: 460159 Cd Length: 128 Bit Score: 59.24 E-value: 1.49e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 7 LTALRSLMKERHMDAYII--PTSdfheteyvgehfkaRKYMSGFSGSQGT-LIVCQDKAALWTD-GRYFIQAENQLQGTT 82
Cdd:pfam01321 2 LEKLRKLMEEKGLDAALVtsPEN--------------LRYLTGFTGSRGLlLLVTADGALLLVDaLEYERAAAESAPDFD 67
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 495965160 83 IdlmkQGEEGVPTMEEYLYENVFEHGTVGFDGRVMNTALVEKLADKL 129
Cdd:pfam01321 68 V----VPYRDYEALADLLKELGAGGKRVGFEADALTVAFYEALKEAL 110
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| APP |
cd01085 |
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline ... |
310-536 |
9.42e-106 |
|
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.
Pssm-ID: 238518 [Multi-domain] Cd Length: 224 Bit Score: 317.97 E-value: 9.42e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 310 NNRKAHIKDAIAMCKFMYWLKAKIGKE-TITEISASAYLETLRKEQ-GCFDISFDTISAYKEHAAMMHYSANEETNAELK 387
Cdd:cd01085 1 GMRAAHIRDGVALVEFLAWLEQEVPKGeTITELSAADKLEEFRRQQkGYVGLSFDTISGFGPNGAIVHYSPTEESNRKIS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 388 PEGMLLVDSGAQYLEGTTDITRTFVLGAISDEIKHHFTTALRSHIALSKAHFLYGCRGLNLDILARGPLWDLALDYKCGT 467
Cdd:cd01085 81 PDGLYLIDSGGQYLDGTTDITRTVHLGEPTAEQKRDYTLVLKGHIALARAKFPKGTTGSQLDALARQPLWKAGLDYGHGT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 495965160 468 GHGVGHVLNVHEGPNGFRwrivpERNDSCVLEEGMTQSNEPGVYVEGSHGIRHENEMVVCKGEKNEYGQ 536
Cdd:cd01085 161 GHGVGSFLNVHEGPQSIS-----PAPNNVPLKAGMILSNEPGYYKEGKYGIRIENLVLVVEAETTEFGG 224
|
|
| Creatinase_N_2 |
pfam16189 |
Creatinase/Prolidase N-terminal domain; |
149-307 |
6.91e-72 |
|
Creatinase/Prolidase N-terminal domain;
Pssm-ID: 465053 Cd Length: 159 Bit Score: 227.76 E-value: 6.91e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 149 DRPALPKKKGFFLEECYSGESTKEKLKRIRAVLKQEKATHHIVTSLDDIAWILNMRGWDIAHFPVMLSYLIIDENSASLY 228
Cdd:pfam16189 1 DRPALPANPVFVLPLKYAGESAAEKLARLREALKEKGADALVLSALDEIAWLLNLRGSDVPYNPVFLSYALVTDDEATLF 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 495965160 229 INESKLDDQLRDNLQENAIVICPYDAIYEDVKKIAQDAVVLLDKTIVNYAITSGLHKEITVINRPNPSQLMKAMKNPIE 307
Cdd:pfam16189 81 VDPEKLSDEVRAHLEENGVEIRPYDDIYEDLAALAAGKKVLLDPSRTSYALYSALPAGAKVVEAPSPITLMKAVKNETE 159
|
|
| PepP |
COG0006 |
Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; |
175-553 |
7.75e-67 |
|
Xaa-Pro aminopeptidase [Amino acid transport and metabolism];
Pssm-ID: 439777 [Multi-domain] Cd Length: 299 Bit Score: 219.69 E-value: 7.75e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 175 KRIRAVLKQEKATHHIVTSLDDIAWILNMRGWdiahfPVMLSYLIIDensaslyinesklddqlrdnlqenaivicpyda 254
Cdd:COG0006 1 ARLRALMAEAGLDALLLTDPSNFAYLTGFRGS-----PERLAALLVT--------------------------------- 42
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 255 iyedvkkiAQDAVVLldktivnyaITSGLHKEITVINRPNPSQLMKAMKNPIELANNRKAHIKDAIAMCKFMYWLKAkiG 334
Cdd:COG0006 43 --------ADGEPVL---------FVDELEAERELVDASDLLEELRAIKSPEEIELMRKAARIADAAHEAALAALRP--G 103
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 335 ketITEISASAYLETLRKEQGCFDISFDTISAYKEHAAMMHYsanEETNAELKPEGMLLVDSGAQYLEGTTDITRTFVLG 414
Cdd:COG0006 104 ---VTEREVAAELEAAMRRRGAEGPSFDTIVASGENAAIPHY---TPTDRPLKPGDLVLIDAGAEYDGYTSDITRTVAVG 177
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 415 AISDEIKHHFTTALRSHIALSKAHfLYGCRGLNLDILARGPLWD--LALDYKCGTGHGVGhvLNVHEGPngfrwRIVPER 492
Cdd:COG0006 178 EPSDEQREIYEAVLEAQEAAIAAL-KPGVTGGEVDAAARDVLAEagYGEYFPHGTGHGVG--LDVHEGP-----QISPGN 249
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 495965160 493 NDscVLEEGMTQSNEPGVYVEGSHGIRHENEMVVckgekNEYGqfmyFETITFVPFDLDGI 553
Cdd:COG0006 250 DR--PLEPGMVFTIEPGIYIPGIGGVRIEDTVLV-----TEDG----AEVLTRLPRELLEL 299
|
|
| Peptidase_M24 |
pfam00557 |
Metallopeptidase family M24; This family contains metallopeptidases. It also contains ... |
312-526 |
5.38e-47 |
|
Metallopeptidase family M24; This family contains metallopeptidases. It also contains non-peptidase homologs such as the N terminal domain of Spt16 which is a histone H3-H4 binding module.
Pssm-ID: 459852 [Multi-domain] Cd Length: 208 Bit Score: 163.95 E-value: 5.38e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 312 RKAHIKDAIAMCKFMYWLKAKIgketiTEISASAYLE-TLRKEQGCFDISFDTISAYKEHAAMMHYSANeetNAELKPEG 390
Cdd:pfam00557 4 RKAARIAAAALEAALAAIRPGV-----TERELAAELEaARLRRGGARGPAFPPIVASGPNAAIPHYIPN---DRVLKPGD 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 391 MLLVDSGAQYLEG-TTDITRTFVLGAISDEIKHHFTTALRSHIALSKAHFlYGCRGLNLDILARGPLWD--LALDYKCGT 467
Cdd:pfam00557 76 LVLIDVGAEYDGGyCSDITRTFVVGKPSPEQRELYEAVLEAQEAAIAAVK-PGVTGGDVDAAAREVLEEagLGEYFPHGL 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 468 GHGVGhvLNVHEGPNgfrwriVPERNDSCVLEEGMTQSNEPGVY-VEGSHGIRHENEMVV 526
Cdd:pfam00557 155 GHGIG--LEVHEGPY------ISRGGDDRVLEPGMVFTIEPGIYfIPGWGGVRIEDTVLV 206
|
|
| Peptidase_M24_C |
pfam16188 |
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of ... |
536-596 |
3.77e-29 |
|
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of metallo-peptidases of the M24 family.
Pssm-ID: 465052 Cd Length: 63 Bit Score: 109.81 E-value: 3.77e-29
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 495965160 536 QFMYFETITFVPFDLDGIDASLLTQYEKAWLNAYHQEVYEKISPYLKEEEQ--SWLREATRAI 596
Cdd:pfam16188 1 PFLGFETLTLVPIDRKLIDVSLLTEEEIEWLNAYHARVREKLSPLLEEEEDalEWLKRATRPI 63
|
|
| PRK09795 |
PRK09795 |
aminopeptidase; Provisional |
299-526 |
2.04e-13 |
|
aminopeptidase; Provisional
Pssm-ID: 182080 [Multi-domain] Cd Length: 361 Bit Score: 71.89 E-value: 2.04e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 299 MKAMKNPIELANNRKA-HIKDAIA--MCKFMywlkakigKETITEISASAYLETLRKEQGCFDISFDTISAYKEHAAMMH 375
Cdd:PRK09795 124 LRQIKTPEEVEKIRLAcGIADRGAehIRRFI--------QAGMSEREIAAELEWFMRQQGAEKASFDTIVASGWRGALPH 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 376 YSANEETNAELKpegMLLVDSGAQYLEGTTDITRTFVLGAISDEIKHH-----FTTALRSHIAlSKAHFLYGCRGLNLDI 450
Cdd:PRK09795 196 GKASDKIVAAGE---FVTLDFGALYQGYCSDMTRTLLVNGEGVSAESHplfnvYQIVLQAQLA-AISAIRPGVRCQQVDD 271
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 495965160 451 LARGPLWDLALDYKCG--TGHGVGhvLNVHEGPngfrwRIVPerNDSCVLEEGMTQSNEPGVYVEGSHGIRHENEMVV 526
Cdd:PRK09795 272 AARRVITEAGYGDYFGhnTGHAIG--IEVHEDP-----RFSP--RDTTTLQPGMLLTVEPGIYLPGQGGVRIEDVVLV 340
|
|
| Creatinase_N |
pfam01321 |
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic ... |
7-129 |
1.49e-10 |
|
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic domains from creatinase and prolidase. The exact function of this domain is uncertain.
Pssm-ID: 460159 Cd Length: 128 Bit Score: 59.24 E-value: 1.49e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 7 LTALRSLMKERHMDAYII--PTSdfheteyvgehfkaRKYMSGFSGSQGT-LIVCQDKAALWTD-GRYFIQAENQLQGTT 82
Cdd:pfam01321 2 LEKLRKLMEEKGLDAALVtsPEN--------------LRYLTGFTGSRGLlLLVTADGALLLVDaLEYERAAAESAPDFD 67
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 495965160 83 IdlmkQGEEGVPTMEEYLYENVFEHGTVGFDGRVMNTALVEKLADKL 129
Cdd:pfam01321 68 V----VPYRDYEALADLLKELGAGGKRVGFEADALTVAFYEALKEAL 110
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| APP |
cd01085 |
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline ... |
310-536 |
9.42e-106 |
|
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.
Pssm-ID: 238518 [Multi-domain] Cd Length: 224 Bit Score: 317.97 E-value: 9.42e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 310 NNRKAHIKDAIAMCKFMYWLKAKIGKE-TITEISASAYLETLRKEQ-GCFDISFDTISAYKEHAAMMHYSANEETNAELK 387
Cdd:cd01085 1 GMRAAHIRDGVALVEFLAWLEQEVPKGeTITELSAADKLEEFRRQQkGYVGLSFDTISGFGPNGAIVHYSPTEESNRKIS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 388 PEGMLLVDSGAQYLEGTTDITRTFVLGAISDEIKHHFTTALRSHIALSKAHFLYGCRGLNLDILARGPLWDLALDYKCGT 467
Cdd:cd01085 81 PDGLYLIDSGGQYLDGTTDITRTVHLGEPTAEQKRDYTLVLKGHIALARAKFPKGTTGSQLDALARQPLWKAGLDYGHGT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 495965160 468 GHGVGHVLNVHEGPNGFRwrivpERNDSCVLEEGMTQSNEPGVYVEGSHGIRHENEMVVCKGEKNEYGQ 536
Cdd:cd01085 161 GHGVGSFLNVHEGPQSIS-----PAPNNVPLKAGMILSNEPGYYKEGKYGIRIENLVLVVEAETTEFGG 224
|
|
| Creatinase_N_2 |
pfam16189 |
Creatinase/Prolidase N-terminal domain; |
149-307 |
6.91e-72 |
|
Creatinase/Prolidase N-terminal domain;
Pssm-ID: 465053 Cd Length: 159 Bit Score: 227.76 E-value: 6.91e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 149 DRPALPKKKGFFLEECYSGESTKEKLKRIRAVLKQEKATHHIVTSLDDIAWILNMRGWDIAHFPVMLSYLIIDENSASLY 228
Cdd:pfam16189 1 DRPALPANPVFVLPLKYAGESAAEKLARLREALKEKGADALVLSALDEIAWLLNLRGSDVPYNPVFLSYALVTDDEATLF 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 495965160 229 INESKLDDQLRDNLQENAIVICPYDAIYEDVKKIAQDAVVLLDKTIVNYAITSGLHKEITVINRPNPSQLMKAMKNPIE 307
Cdd:pfam16189 81 VDPEKLSDEVRAHLEENGVEIRPYDDIYEDLAALAAGKKVLLDPSRTSYALYSALPAGAKVVEAPSPITLMKAVKNETE 159
|
|
| PepP |
COG0006 |
Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; |
175-553 |
7.75e-67 |
|
Xaa-Pro aminopeptidase [Amino acid transport and metabolism];
Pssm-ID: 439777 [Multi-domain] Cd Length: 299 Bit Score: 219.69 E-value: 7.75e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 175 KRIRAVLKQEKATHHIVTSLDDIAWILNMRGWdiahfPVMLSYLIIDensaslyinesklddqlrdnlqenaivicpyda 254
Cdd:COG0006 1 ARLRALMAEAGLDALLLTDPSNFAYLTGFRGS-----PERLAALLVT--------------------------------- 42
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 255 iyedvkkiAQDAVVLldktivnyaITSGLHKEITVINRPNPSQLMKAMKNPIELANNRKAHIKDAIAMCKFMYWLKAkiG 334
Cdd:COG0006 43 --------ADGEPVL---------FVDELEAERELVDASDLLEELRAIKSPEEIELMRKAARIADAAHEAALAALRP--G 103
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 335 ketITEISASAYLETLRKEQGCFDISFDTISAYKEHAAMMHYsanEETNAELKPEGMLLVDSGAQYLEGTTDITRTFVLG 414
Cdd:COG0006 104 ---VTEREVAAELEAAMRRRGAEGPSFDTIVASGENAAIPHY---TPTDRPLKPGDLVLIDAGAEYDGYTSDITRTVAVG 177
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 415 AISDEIKHHFTTALRSHIALSKAHfLYGCRGLNLDILARGPLWD--LALDYKCGTGHGVGhvLNVHEGPngfrwRIVPER 492
Cdd:COG0006 178 EPSDEQREIYEAVLEAQEAAIAAL-KPGVTGGEVDAAARDVLAEagYGEYFPHGTGHGVG--LDVHEGP-----QISPGN 249
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 495965160 493 NDscVLEEGMTQSNEPGVYVEGSHGIRHENEMVVckgekNEYGqfmyFETITFVPFDLDGI 553
Cdd:COG0006 250 DR--PLEPGMVFTIEPGIYIPGIGGVRIEDTVLV-----TEDG----AEVLTRLPRELLEL 299
|
|
| Peptidase_M24 |
pfam00557 |
Metallopeptidase family M24; This family contains metallopeptidases. It also contains ... |
312-526 |
5.38e-47 |
|
Metallopeptidase family M24; This family contains metallopeptidases. It also contains non-peptidase homologs such as the N terminal domain of Spt16 which is a histone H3-H4 binding module.
Pssm-ID: 459852 [Multi-domain] Cd Length: 208 Bit Score: 163.95 E-value: 5.38e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 312 RKAHIKDAIAMCKFMYWLKAKIgketiTEISASAYLE-TLRKEQGCFDISFDTISAYKEHAAMMHYSANeetNAELKPEG 390
Cdd:pfam00557 4 RKAARIAAAALEAALAAIRPGV-----TERELAAELEaARLRRGGARGPAFPPIVASGPNAAIPHYIPN---DRVLKPGD 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 391 MLLVDSGAQYLEG-TTDITRTFVLGAISDEIKHHFTTALRSHIALSKAHFlYGCRGLNLDILARGPLWD--LALDYKCGT 467
Cdd:pfam00557 76 LVLIDVGAEYDGGyCSDITRTFVVGKPSPEQRELYEAVLEAQEAAIAAVK-PGVTGGDVDAAAREVLEEagLGEYFPHGL 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 468 GHGVGhvLNVHEGPNgfrwriVPERNDSCVLEEGMTQSNEPGVY-VEGSHGIRHENEMVV 526
Cdd:pfam00557 155 GHGIG--LEVHEGPY------ISRGGDDRVLEPGMVFTIEPGIYfIPGWGGVRIEDTVLV 206
|
|
| APP-like |
cd01092 |
Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse ... |
332-531 |
1.38e-31 |
|
Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline.
Pssm-ID: 238525 [Multi-domain] Cd Length: 208 Bit Score: 121.46 E-value: 1.38e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 332 KIGKETITEISASAYLETLRKEQGCFDISFDTISAYKEHAAMMHYSAneeTNAELKPEGMLLVDSGAQYlEG-TTDITRT 410
Cdd:cd01092 20 EFIKPGMTEREVAAELEYFMRKLGAEGPSFDTIVASGPNSALPHGVP---SDRKIEEGDLVLIDFGAIY-DGyCSDITRT 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 411 FVLGAISDEIKHHFTTALRSHIALSKAhFLYGCRGLNLDILARGPLWDLAL-DYKC-GTGHGVGhvLNVHEGPNgfrwri 488
Cdd:cd01092 96 VAVGEPSDELKEIYEIVLEAQQAAIKA-VKPGVTAKEVDKAARDVIEEAGYgEYFIhRTGHGVG--LEVHEAPY------ 166
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 495965160 489 VPERNDScVLEEGMTQSNEPGVYVEGSHGIRHENeMVVCKGEK 531
Cdd:cd01092 167 ISPGSDD-VLEEGMVFTIEPGIYIPGKGGVRIED-DVLVTEDG 207
|
|
| Peptidase_M24_C |
pfam16188 |
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of ... |
536-596 |
3.77e-29 |
|
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of metallo-peptidases of the M24 family.
Pssm-ID: 465052 Cd Length: 63 Bit Score: 109.81 E-value: 3.77e-29
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 495965160 536 QFMYFETITFVPFDLDGIDASLLTQYEKAWLNAYHQEVYEKISPYLKEEEQ--SWLREATRAI 596
Cdd:pfam16188 1 PFLGFETLTLVPIDRKLIDVSLLTEEEIEWLNAYHARVREKLSPLLEEEEDalEWLKRATRPI 63
|
|
| APP_MetAP |
cd01066 |
A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as ... |
335-526 |
2.16e-19 |
|
A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity compared to other metallo-aminopeptidases, suggesting they play roles in regulation of biological processes rather than general protein degradation.
Pssm-ID: 238514 [Multi-domain] Cd Length: 207 Bit Score: 86.74 E-value: 2.16e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 335 KETITEISASAYLETLRKEQGCFdISFDTISAYKEHAAMMHYSANEETnaeLKPEGMLLVDSGAQYLEGTTDITRTFVLG 414
Cdd:cd01066 23 RPGVTEAEVAAAIEQALRAAGGY-PAGPTIVGSGARTALPHYRPDDRR---LQEGDLVLVDLGGVYDGYHADLTRTFVIG 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 415 AISDEIKHHFTTALRSHIALSKAHFlYGCRGLNLDILARGPL--WDLALDYKCGTGHGVGhvLNVHEGPngfrwriVPER 492
Cdd:cd01066 99 EPSDEQRELYEAVREAQEAALAALR-PGVTAEEVDAAAREVLeeHGLGPNFGHRTGHGIG--LEIHEPP-------VLKA 168
|
170 180 190
....*....|....*....|....*....|....
gi 495965160 493 NDSCVLEEGMTQSNEPGVYVEGSHGIRHENEMVV 526
Cdd:cd01066 169 GDDTVLEPGMVFAVEPGLYLPGGGGVRIEDTVLV 202
|
|
| PRK09795 |
PRK09795 |
aminopeptidase; Provisional |
299-526 |
2.04e-13 |
|
aminopeptidase; Provisional
Pssm-ID: 182080 [Multi-domain] Cd Length: 361 Bit Score: 71.89 E-value: 2.04e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 299 MKAMKNPIELANNRKA-HIKDAIA--MCKFMywlkakigKETITEISASAYLETLRKEQGCFDISFDTISAYKEHAAMMH 375
Cdd:PRK09795 124 LRQIKTPEEVEKIRLAcGIADRGAehIRRFI--------QAGMSEREIAAELEWFMRQQGAEKASFDTIVASGWRGALPH 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 376 YSANEETNAELKpegMLLVDSGAQYLEGTTDITRTFVLGAISDEIKHH-----FTTALRSHIAlSKAHFLYGCRGLNLDI 450
Cdd:PRK09795 196 GKASDKIVAAGE---FVTLDFGALYQGYCSDMTRTLLVNGEGVSAESHplfnvYQIVLQAQLA-AISAIRPGVRCQQVDD 271
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 495965160 451 LARGPLWDLALDYKCG--TGHGVGhvLNVHEGPngfrwRIVPerNDSCVLEEGMTQSNEPGVYVEGSHGIRHENEMVV 526
Cdd:PRK09795 272 AARRVITEAGYGDYFGhnTGHAIG--IEVHEDP-----RFSP--RDTTTLQPGMLLTVEPGIYLPGQGGVRIEDVVLV 340
|
|
| Prolidase |
cd01087 |
Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline ... |
335-526 |
1.88e-11 |
|
Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-Pro.
Pssm-ID: 238520 [Multi-domain] Cd Length: 243 Bit Score: 64.52 E-value: 1.88e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 335 KETITEISASAYLETLRKEQGCfDISFDTISAYKEHAAMMHYSANeetNAELKPEGMLLVDSGAQYLEGTTDITRTF-VL 413
Cdd:cd01087 23 RPGMSEYELEAEFEYEFRSRGA-RLAYSYIVAAGSNAAILHYVHN---DQPLKDGDLVLIDAGAEYGGYASDITRTFpVN 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 414 GAISDEIKHHFTTALRSH---IALSK-----------AHFLYGCRGLNLDILaRGPLWDL------ALDYKCGTGHGVGh 473
Cdd:cd01087 99 GKFTDEQRELYEAVLAAQkaaIAACKpgvsyedihllAHRVLAEGLKELGIL-KGDVDEIvesgayAKFFPHGLGHYLG- 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 495965160 474 vLNVHEGPNGF----RWRIvperndscvLEEGMTQSNEPGVYVEGSH----------GIRHENEMVV 526
Cdd:cd01087 177 -LDVHDVGGYLrylrRARP---------LEPGMVITIEPGIYFIPDLldvpeyfrggGIRIEDDVLV 233
|
|
| Creatinase_N |
pfam01321 |
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic ... |
7-129 |
1.49e-10 |
|
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic domains from creatinase and prolidase. The exact function of this domain is uncertain.
Pssm-ID: 460159 Cd Length: 128 Bit Score: 59.24 E-value: 1.49e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 7 LTALRSLMKERHMDAYII--PTSdfheteyvgehfkaRKYMSGFSGSQGT-LIVCQDKAALWTD-GRYFIQAENQLQGTT 82
Cdd:pfam01321 2 LEKLRKLMEEKGLDAALVtsPEN--------------LRYLTGFTGSRGLlLLVTADGALLLVDaLEYERAAAESAPDFD 67
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 495965160 83 IdlmkQGEEGVPTMEEYLYENVFEHGTVGFDGRVMNTALVEKLADKL 129
Cdd:pfam01321 68 V----VPYRDYEALADLLKELGAGGKRVGFEADALTVAFYEALKEAL 110
|
|
| PRK10879 |
PRK10879 |
proline aminopeptidase P II; Provisional |
299-526 |
1.27e-06 |
|
proline aminopeptidase P II; Provisional
Pssm-ID: 182804 [Multi-domain] Cd Length: 438 Bit Score: 51.26 E-value: 1.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 299 MKAMKNPIELANNRKA-------HIKdAIAMCK---FMYWLKAKIGKETIteisasayletlrkEQGCFDISFDTISAYK 368
Cdd:PRK10879 170 MRLFKSPEEIAVLRRAgeisalaHTR-AMEKCRpgmFEYQLEGEIHHEFN--------------RHGARYPSYNTIVGSG 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 369 EHAAMMHYSANEetnAELKPEGMLLVDSGAQYLEGTTDITRTF-VLGAISDEIKHHFTTALRShiaLSKAHFLYG----- 442
Cdd:PRK10879 235 ENGCILHYTENE---SEMRDGDLVLIDAGCEYKGYAGDITRTFpVNGKFTPAQREIYDIVLES---LETSLRLYRpgtsi 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 443 -----------CRGL-NLDILaRGPLWDLALD--YKCGTGHGVGHVL--NVHE-GPNGfrwrivPERndSCVLEEGMTQS 505
Cdd:PRK10879 309 revtgevvrimVSGLvKLGIL-KGDVDQLIAEnaHRPFFMHGLSHWLglDVHDvGVYG------QDR--SRILEPGMVLT 379
|
250 260 270
....*....|....*....|....*....|
gi 495965160 506 NEPGVYVEGSH---------GIRHENEMVV 526
Cdd:PRK10879 380 VEPGLYIAPDAdvpeqyrgiGIRIEDDIVI 409
|
|
| PRK13607 |
PRK13607 |
proline dipeptidase; Provisional |
345-412 |
2.34e-04 |
|
proline dipeptidase; Provisional
Pssm-ID: 237444 [Multi-domain] Cd Length: 443 Bit Score: 43.73 E-value: 2.34e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965160 345 AYLETLRkeQGCFDISFDTISAYKEHAAMMHYSANEETnaelKPEGM--LLVDSGAQYLEGTTDITRTFV 412
Cdd:PRK13607 200 AYLTATG--QRDNDVPYGNIVALNEHAAVLHYTKLDHQ----APAEMrsFLIDAGAEYNGYAADITRTYA 263
|
|
| PRK12896 |
PRK12896 |
methionine aminopeptidase; Reviewed |
467-508 |
9.28e-03 |
|
methionine aminopeptidase; Reviewed
Pssm-ID: 237252 [Multi-domain] Cd Length: 255 Bit Score: 38.28 E-value: 9.28e-03
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 495965160 467 TGHGVGhvLNVHEGPNGFRWRivPERNDSCVLEEGMTQSNEP 508
Cdd:PRK12896 172 TGHGVG--RSLHEEPSVILTY--TDPLPNRLLRPGMTLAVEP 209
|
|
| |
