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Conserved domains on  [gi|495316244|ref|WP_008040991|]
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MULTISPECIES: class 1 fructose-bisphosphatase [Pseudomonas]

Protein Classification

class 1 fructose-1,6-bisphosphatase( domain architecture ID 10000674)

class 1 fructose-1,6-bisphosphatase I catalyzes the conversion of D-fructose 1,6-bisphosphate to D-fructose 6-phosphate in gluconeogenesis and the Calvin cycle, which are both anabolic pathways

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Fbp COG0158
Fructose-1,6-bisphosphatase [Carbohydrate transport and metabolism]; Fructose-1, ...
1-336 0e+00

Fructose-1,6-bisphosphatase [Carbohydrate transport and metabolism]; Fructose-1,6-bisphosphatase is part of the Pathway/BioSystem: Gluconeogenesis


:

Pssm-ID: 439928 [Multi-domain]  Cd Length: 338  Bit Score: 663.74  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244   1 MSRVTLSRYLIEQTRSNNT-PADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQGEVQKKLDVMSNDILLEANE 79
Cdd:COG0158    2 MKGTTLTQFLIEQQRRFPGaTGELSALLNAIALAAKIISREVNKGGLAGILGAAGSENVQGETQKKLDVIANEIFIEALE 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244  80 WGGHLAGMASEEMDNAYQIPGKYPKGAYLLVFDPLDGSSNIDINAPVGTIFSVLRCPNEyltqNEPLNEKAFLQPGAQQV 159
Cdd:COG0158   82 WGGHVAAMASEEMDDPIPIPEQYPRGKYLVLFDPLDGSSNIDVNVSVGTIFSILRRPSG----GGPVTEEDFLQPGSEQV 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244 160 AAGYAIYGPQTMLVLTLGNGVKGFTLDREMGSFVLTHEDITIPESTQEFAINASNQRHWEAPVQRYVSELLAGDEGPLKK 239
Cdd:COG0158  158 AAGYVLYGPSTMLVLTTGNGVHGFTLDPSIGEFLLTHPNMRIPEDTKEYAINESNYRHWEPPVRRYIDECLAGKEGPRGR 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244 240 NYNMRWVAAMVADVHRILTRGGLFMYPRDSREPSKPGKLRLMYEANPMSFLVEQAGGASTDGHQRILDIQPEGLHQRVAV 319
Cdd:COG0158  238 DFNMRWIGSLVADVHRILLRGGIFLYPADSRDGYPPGKLRLLYEANPMAFLVEQAGGAATDGRQRILDIVPTSLHQRVPL 317
                        330
                 ....*....|....*..
gi 495316244 320 FLGSKEEVARVTAYHKE 336
Cdd:COG0158  318 ILGSKEEVERVERYHAE 334
 
Name Accession Description Interval E-value
Fbp COG0158
Fructose-1,6-bisphosphatase [Carbohydrate transport and metabolism]; Fructose-1, ...
1-336 0e+00

Fructose-1,6-bisphosphatase [Carbohydrate transport and metabolism]; Fructose-1,6-bisphosphatase is part of the Pathway/BioSystem: Gluconeogenesis


Pssm-ID: 439928 [Multi-domain]  Cd Length: 338  Bit Score: 663.74  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244   1 MSRVTLSRYLIEQTRSNNT-PADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQGEVQKKLDVMSNDILLEANE 79
Cdd:COG0158    2 MKGTTLTQFLIEQQRRFPGaTGELSALLNAIALAAKIISREVNKGGLAGILGAAGSENVQGETQKKLDVIANEIFIEALE 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244  80 WGGHLAGMASEEMDNAYQIPGKYPKGAYLLVFDPLDGSSNIDINAPVGTIFSVLRCPNEyltqNEPLNEKAFLQPGAQQV 159
Cdd:COG0158   82 WGGHVAAMASEEMDDPIPIPEQYPRGKYLVLFDPLDGSSNIDVNVSVGTIFSILRRPSG----GGPVTEEDFLQPGSEQV 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244 160 AAGYAIYGPQTMLVLTLGNGVKGFTLDREMGSFVLTHEDITIPESTQEFAINASNQRHWEAPVQRYVSELLAGDEGPLKK 239
Cdd:COG0158  158 AAGYVLYGPSTMLVLTTGNGVHGFTLDPSIGEFLLTHPNMRIPEDTKEYAINESNYRHWEPPVRRYIDECLAGKEGPRGR 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244 240 NYNMRWVAAMVADVHRILTRGGLFMYPRDSREPSKPGKLRLMYEANPMSFLVEQAGGASTDGHQRILDIQPEGLHQRVAV 319
Cdd:COG0158  238 DFNMRWIGSLVADVHRILLRGGIFLYPADSRDGYPPGKLRLLYEANPMAFLVEQAGGAATDGRQRILDIVPTSLHQRVPL 317
                        330
                 ....*....|....*..
gi 495316244 320 FLGSKEEVARVTAYHKE 336
Cdd:COG0158  318 ILGSKEEVERVERYHAE 334
PRK09293 PRK09293
class 1 fructose-bisphosphatase;
2-336 0e+00

class 1 fructose-bisphosphatase;


Pssm-ID: 236458 [Multi-domain]  Cd Length: 327  Bit Score: 569.48  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244   2 SRVTLSRYLIEQTRSN-NTPADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQGEVQKKLDVMSNDILLEANEW 80
Cdd:PRK09293   1 SMKTLGEFLVEQQREFpHATGELTALISAIALAAKIISRAINKGGLADILGAAGTENVQGETQKKLDVFANEILIEALKA 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244  81 GGHLAGMASEEMDNAYQIPGKypKGAYLLVFDPLDGSSNIDINAPVGTIFSVLRCPNEyltqnePLNEKAFLQPGAQQVA 160
Cdd:PRK09293  81 RGHVAGLASEEEDEIVPIPEN--EGKYLVAYDPLDGSSNIDVNVSVGTIFSIYRAPVG------TPTEEDFLQPGNNQVA 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244 161 AGYAIYGPQTMLVLTLGNGVKGFTLDREMGSFVLTHEDITIPESTQEFAINASNQRHWEAPVQRYVsELLAGDEGPLKKN 240
Cdd:PRK09293 153 AGYVLYGPSTMLVLTTGDGVHGFTLDPSLGEFVLTHENIRIPEDGKEYAINEGNQRHWEPGVKKYI-ELLAGKDGPRGRP 231
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244 241 YNMRWVAAMVADVHRILTRGGLFMYPRDSrePSKPGKLRLMYEANPMSFLVEQAGGASTDGHQRILDIQPEGLHQRVAVF 320
Cdd:PRK09293 232 YNMRYIGSMVADVHRILLKGGIFLYPADE--PYPNGKLRLLYEANPMAFLVEQAGGAASDGKQRILDIEPESLHQRVPLF 309
                        330
                 ....*....|....*.
gi 495316244 321 LGSKEEVARVTAYHKE 336
Cdd:PRK09293 310 LGSKEEVERVEEYHAE 325
FBPase cd00354
Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1, ...
10-334 0e+00

Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1,7-biphosphatases that play a role in pentose phosphate pathway (Calvin cycle).


Pssm-ID: 238214 [Multi-domain]  Cd Length: 315  Bit Score: 519.03  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244  10 LIEQTRSNNTPADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQGEVQKKLDVMSNDILLEANEWGGHLAGMAS 89
Cdd:cd00354    1 LLEQLRKGAATGDLTDLLSSLALACKEISRAVRRAGLAGLLGLAGSVNVQGDEQKKLDVLANDIFIEALKSSGVVAVLAS 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244  90 EEMDNAYQIPGKYpKGAYLLVFDPLDGSSNIDINAPVGTIFSVLRCPNEyltqnEPLNEKAFLQPGAQQVAAGYAIYGPQ 169
Cdd:cd00354   81 EEEEEPVPVEESK-DGKYLVAFDPLDGSSNIDANVSVGTIFSIYPGPSG-----ADATEKDFLQPGRNQVAAGYALYGPS 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244 170 TMLVLTLGNGVKGFTLDREMGSFVLTHEDITIPESTQEFAINASNQRHWEAPVQRYVSELLAGDEGplKKNYNMRWVAAM 249
Cdd:cd00354  155 TMLVLTLGQGVHGFTLDPSLGEFILTHPNVKIPKKGKIYSINEGNYRYWDEPVKKYIDDCKAGEDG--GKPYNLRYIGSM 232
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244 250 VADVHRILTRGGLFMYPRDSRepSKPGKLRLMYEANPMSFLVEQAGGASTDGHQRILDIQPEGLHQRVAVFLGSKEEVAR 329
Cdd:cd00354  233 VADVHRILVRGGIFLYPADKK--SPKGKLRLLYEANPMAFLVEQAGGKATDGKERILDIVPTSLHQRVPVILGSKEEVER 310

                 ....*
gi 495316244 330 VTAYH 334
Cdd:cd00354  311 VEEYL 315
FBPase_C pfam18913
Fructose-1-6-bisphosphatase, C-terminal domain; This entry represents the C-terminal domain of ...
203-335 2.38e-66

Fructose-1-6-bisphosphatase, C-terminal domain; This entry represents the C-terminal domain of Fructose-1-6-bisphosphatase enzymes. According to ECOD this domain has a Rossmann-like fold.


Pssm-ID: 436826 [Multi-domain]  Cd Length: 125  Bit Score: 204.77  E-value: 2.38e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244  203 ESTQEFAINASNQRHWEAPVQRYVSELLAGdegplkKNYNMRWVAAMVADVHRILTRGGLFMYPRDSREPSkpGKLRLMY 282
Cdd:pfam18913   1 EEGKIYAINEGNARFWNAPYRAYIDDLVSG------KGYTLRYIGSMVADVHRILLKGGIFLYPADRRSPY--GKLRLLY 72
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 495316244  283 EANPMSFLVEQAGGASTDGHQRILDIQPEGLHQRVAVFLGSKEEVARVTAYHK 335
Cdd:pfam18913  73 ECAPLAFLIEQAGGKASDGTQRILDIVPDSLHQRTPIFLGSRDEVARVEAYLK 125
 
Name Accession Description Interval E-value
Fbp COG0158
Fructose-1,6-bisphosphatase [Carbohydrate transport and metabolism]; Fructose-1, ...
1-336 0e+00

Fructose-1,6-bisphosphatase [Carbohydrate transport and metabolism]; Fructose-1,6-bisphosphatase is part of the Pathway/BioSystem: Gluconeogenesis


Pssm-ID: 439928 [Multi-domain]  Cd Length: 338  Bit Score: 663.74  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244   1 MSRVTLSRYLIEQTRSNNT-PADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQGEVQKKLDVMSNDILLEANE 79
Cdd:COG0158    2 MKGTTLTQFLIEQQRRFPGaTGELSALLNAIALAAKIISREVNKGGLAGILGAAGSENVQGETQKKLDVIANEIFIEALE 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244  80 WGGHLAGMASEEMDNAYQIPGKYPKGAYLLVFDPLDGSSNIDINAPVGTIFSVLRCPNEyltqNEPLNEKAFLQPGAQQV 159
Cdd:COG0158   82 WGGHVAAMASEEMDDPIPIPEQYPRGKYLVLFDPLDGSSNIDVNVSVGTIFSILRRPSG----GGPVTEEDFLQPGSEQV 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244 160 AAGYAIYGPQTMLVLTLGNGVKGFTLDREMGSFVLTHEDITIPESTQEFAINASNQRHWEAPVQRYVSELLAGDEGPLKK 239
Cdd:COG0158  158 AAGYVLYGPSTMLVLTTGNGVHGFTLDPSIGEFLLTHPNMRIPEDTKEYAINESNYRHWEPPVRRYIDECLAGKEGPRGR 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244 240 NYNMRWVAAMVADVHRILTRGGLFMYPRDSREPSKPGKLRLMYEANPMSFLVEQAGGASTDGHQRILDIQPEGLHQRVAV 319
Cdd:COG0158  238 DFNMRWIGSLVADVHRILLRGGIFLYPADSRDGYPPGKLRLLYEANPMAFLVEQAGGAATDGRQRILDIVPTSLHQRVPL 317
                        330
                 ....*....|....*..
gi 495316244 320 FLGSKEEVARVTAYHKE 336
Cdd:COG0158  318 ILGSKEEVERVERYHAE 334
PRK09293 PRK09293
class 1 fructose-bisphosphatase;
2-336 0e+00

class 1 fructose-bisphosphatase;


Pssm-ID: 236458 [Multi-domain]  Cd Length: 327  Bit Score: 569.48  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244   2 SRVTLSRYLIEQTRSN-NTPADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQGEVQKKLDVMSNDILLEANEW 80
Cdd:PRK09293   1 SMKTLGEFLVEQQREFpHATGELTALISAIALAAKIISRAINKGGLADILGAAGTENVQGETQKKLDVFANEILIEALKA 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244  81 GGHLAGMASEEMDNAYQIPGKypKGAYLLVFDPLDGSSNIDINAPVGTIFSVLRCPNEyltqnePLNEKAFLQPGAQQVA 160
Cdd:PRK09293  81 RGHVAGLASEEEDEIVPIPEN--EGKYLVAYDPLDGSSNIDVNVSVGTIFSIYRAPVG------TPTEEDFLQPGNNQVA 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244 161 AGYAIYGPQTMLVLTLGNGVKGFTLDREMGSFVLTHEDITIPESTQEFAINASNQRHWEAPVQRYVsELLAGDEGPLKKN 240
Cdd:PRK09293 153 AGYVLYGPSTMLVLTTGDGVHGFTLDPSLGEFVLTHENIRIPEDGKEYAINEGNQRHWEPGVKKYI-ELLAGKDGPRGRP 231
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244 241 YNMRWVAAMVADVHRILTRGGLFMYPRDSrePSKPGKLRLMYEANPMSFLVEQAGGASTDGHQRILDIQPEGLHQRVAVF 320
Cdd:PRK09293 232 YNMRYIGSMVADVHRILLKGGIFLYPADE--PYPNGKLRLLYEANPMAFLVEQAGGAASDGKQRILDIEPESLHQRVPLF 309
                        330
                 ....*....|....*.
gi 495316244 321 LGSKEEVARVTAYHKE 336
Cdd:PRK09293 310 LGSKEEVERVEEYHAE 325
FBPase cd00354
Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1, ...
10-334 0e+00

Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1,7-biphosphatases that play a role in pentose phosphate pathway (Calvin cycle).


Pssm-ID: 238214 [Multi-domain]  Cd Length: 315  Bit Score: 519.03  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244  10 LIEQTRSNNTPADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQGEVQKKLDVMSNDILLEANEWGGHLAGMAS 89
Cdd:cd00354    1 LLEQLRKGAATGDLTDLLSSLALACKEISRAVRRAGLAGLLGLAGSVNVQGDEQKKLDVLANDIFIEALKSSGVVAVLAS 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244  90 EEMDNAYQIPGKYpKGAYLLVFDPLDGSSNIDINAPVGTIFSVLRCPNEyltqnEPLNEKAFLQPGAQQVAAGYAIYGPQ 169
Cdd:cd00354   81 EEEEEPVPVEESK-DGKYLVAFDPLDGSSNIDANVSVGTIFSIYPGPSG-----ADATEKDFLQPGRNQVAAGYALYGPS 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244 170 TMLVLTLGNGVKGFTLDREMGSFVLTHEDITIPESTQEFAINASNQRHWEAPVQRYVSELLAGDEGplKKNYNMRWVAAM 249
Cdd:cd00354  155 TMLVLTLGQGVHGFTLDPSLGEFILTHPNVKIPKKGKIYSINEGNYRYWDEPVKKYIDDCKAGEDG--GKPYNLRYIGSM 232
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244 250 VADVHRILTRGGLFMYPRDSRepSKPGKLRLMYEANPMSFLVEQAGGASTDGHQRILDIQPEGLHQRVAVFLGSKEEVAR 329
Cdd:cd00354  233 VADVHRILVRGGIFLYPADKK--SPKGKLRLLYEANPMAFLVEQAGGKATDGKERILDIVPTSLHQRVPVILGSKEEVER 310

                 ....*
gi 495316244 330 VTAYH 334
Cdd:cd00354  311 VEEYL 315
PLN02262 PLN02262
fructose-1,6-bisphosphatase
4-336 1.88e-109

fructose-1,6-bisphosphatase


Pssm-ID: 215147 [Multi-domain]  Cd Length: 340  Bit Score: 322.53  E-value: 1.88e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244   4 VTLSRY-LIEQTRSNNTPADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQGEVQKKLDVMSNDILLEANEWGG 82
Cdd:PLN02262  13 MTITRFvLNEQSKHPEARGDLTILLSHIVLGCKFVCSAVNKAGLAKLIGLAGETNVQGEEQKKLDVLSNDVFIKALVSSG 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244  83 HLAGMASEEMDNA-YQIPGkyPKGAYLLVFDPLDGSSNIDINAPVGTIFSVLRCPNEyltqNEPLNEKAfLQPGAQQVAA 161
Cdd:PLN02262  93 RTNVLVSEEDEEAiFVEPS--KRGRYCVVFDPLDGSSNIDCGVSIGTIFGIYMLKDG----GEGTVEDV-LQPGKEMVAA 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244 162 GYAIYGPQTMLVLTLGNGVKGFTLDREMGSFVLTHEDITIPESTQEFAINASNQRHWEAPVQRYVSELLAGDEGPLKKny 241
Cdd:PLN02262 166 GYCMYGSSCTLVLSTGGGVNGFTLDPSLGEFILTHPDIKIPKKGKIYSVNEGNAKNWDGPTAKYVEKCKFPKDGSSPK-- 243
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244 242 NMRWVAAMVADVHRILTRGGLFMYPRDSREPSkpGKLRLMYEANPMSFLVEQAGGASTDGHQRILDIQPEGLHQRVAVFL 321
Cdd:PLN02262 244 SLRYIGSMVADVHRTLLYGGIFLYPADKKSPN--GKLRVLYEVFPMSFLVEQAGGQAFTGKQRALDLVPTKIHERSPIFL 321
                        330
                 ....*....|....*
gi 495316244 322 GSKEEVARVTAYHKE 336
Cdd:PLN02262 322 GSYDDVEEIKALYAA 336
PLN02542 PLN02542
fructose-1,6-bisphosphatase
5-333 4.07e-95

fructose-1,6-bisphosphatase


Pssm-ID: 215298 [Multi-domain]  Cd Length: 412  Bit Score: 288.31  E-value: 4.07e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244   5 TLSRYLIEQTRSNNTPADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQGEVQKKLDVMSNDILLEANEWGGHL 84
Cdd:PLN02542  78 TLTTWLLKQEQAGVIDAELTIVLSSISMACKQIASLVQRAGISNLTGVQGAVNIQGEDQKKLDVISNEVFSNCLRSSGRT 157
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244  85 AGMASEEMDNAYQIPGKYpKGAYLLVFDPLDGSSNIDINAPVGTIFSVLRCPNEYLT---QNEPLNEKA------FLQPG 155
Cdd:PLN02542 158 GIIASEEEDVPVAVEESY-SGNYIVVFDPLDGSSNIDAAVSTGSIFGIYSPNDECLAdigDDSTLDSVEqrcivnVCQPG 236
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244 156 AQQVAAGYAIYGPQTMLVLTLGNGVKGFTLDREMGSFVLTHEDITIPESTQEFAINASNQRHWEAPVQRYVSELlaGDEG 235
Cdd:PLN02542 237 SNLLAAGYCMYSSSVIFVLTIGTGVFSFTLDPMYGEFVLTQENIQIPKAGKIYSFNEGNYQLWDDKLKKYIDDL--KDPG 314
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244 236 PLKKNYNMRWVAAMVADVHRILTRGGLFMYPRDSRepSKPGKLRLMYEANPMSFLVEQAGGASTDGHQRILDIQPEGLHQ 315
Cdd:PLN02542 315 PSGKPYSARYIGSLVGDFHRTLLYGGIYGYPRDKK--SKNGKLRLLYECAPMSFIVEQAGGKGSDGHQRILDIQPTEIHQ 392
                        330
                 ....*....|....*...
gi 495316244 316 RVAVFLGSKEEVARVTAY 333
Cdd:PLN02542 393 RVPLYIGSVEEVEKLEKY 410
PLN02628 PLN02628
fructose-1,6-bisphosphatase family protein
5-333 1.62e-87

fructose-1,6-bisphosphatase family protein


Pssm-ID: 215337 [Multi-domain]  Cd Length: 351  Bit Score: 266.66  E-value: 1.62e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244   5 TLSRYLieQTRSNNTPADLRFLIEVVARACKEISHAVS---KGALGGVL-GSMGTENVQGEVQKKLDVMSNDILLEANEW 80
Cdd:PLN02628  19 TLMEFL--GTEGSNVGDDLVVLMAHIQAACKRIAALLAspfNSELGKTSsGASGASGSGRDAPKPLDIVSNEIILSSLRN 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244  81 GGHLAGMASEEMDNAYQIPGKypkGAYLLVFDPLDGSSNIDINAPVGTIFSVLRCPNEylTQNEPLNEKAF---LQPGAQ 157
Cdd:PLN02628  97 SGKVAVMASEEDDAPIWIGDD---GPYVVVFDPLDGSRNIDASIPTGTIFGIYNRLVE--ADHLPVEEKAQlnvLQRGSR 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244 158 QVAAGYAIYGPQTMLVLTLGNGVKGFTLDREMGSFVLTHEDITIPESTQEFAINASNQRHWEAPVQRYVSELLAGdEGPL 237
Cdd:PLN02628 172 LVAAGYVLYSSATILCISFGSGTHGFTLDHSTGEFVLTHPDIKIPERGQIYSVNDARYFDWPEGLRKYIDTVRQG-KGQY 250
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244 238 KKNYNMRWVAAMVADVHRILTRGGLFMYPRDsrepskpgKLRLMYEANPMSFLVEQAGGASTDGHQRILDIQPEGLHQRV 317
Cdd:PLN02628 251 PKKYSARYICSLVADLHRTILYGGIAMNPRS--------HLRLVYEANPLSFLVEQAGGRGSDGKRRILSIQPVKLHQRL 322
                        330
                 ....*....|....*.
gi 495316244 318 AVFLGSKEEVARVTAY 333
Cdd:PLN02628 323 PLFLGSSEDVLELESY 338
FBPase_C pfam18913
Fructose-1-6-bisphosphatase, C-terminal domain; This entry represents the C-terminal domain of ...
203-335 2.38e-66

Fructose-1-6-bisphosphatase, C-terminal domain; This entry represents the C-terminal domain of Fructose-1-6-bisphosphatase enzymes. According to ECOD this domain has a Rossmann-like fold.


Pssm-ID: 436826 [Multi-domain]  Cd Length: 125  Bit Score: 204.77  E-value: 2.38e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244  203 ESTQEFAINASNQRHWEAPVQRYVSELLAGdegplkKNYNMRWVAAMVADVHRILTRGGLFMYPRDSREPSkpGKLRLMY 282
Cdd:pfam18913   1 EEGKIYAINEGNARFWNAPYRAYIDDLVSG------KGYTLRYIGSMVADVHRILLKGGIFLYPADRRSPY--GKLRLLY 72
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 495316244  283 EANPMSFLVEQAGGASTDGHQRILDIQPEGLHQRVAVFLGSKEEVARVTAYHK 335
Cdd:pfam18913  73 ECAPLAFLIEQAGGKASDGTQRILDIVPDSLHQRTPIFLGSRDEVARVEAYLK 125
FBPase pfam00316
Fructose-1-6-bisphosphatase, N-terminal domain; This family represents the N-terminus of this ...
5-197 8.76e-62

Fructose-1-6-bisphosphatase, N-terminal domain; This family represents the N-terminus of this protein family.


Pssm-ID: 425601  Cd Length: 191  Bit Score: 195.37  E-value: 8.76e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244    5 TLSRYLIEQTR-SNNTPADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQGEVQKKLDVMSNDILLEANEWGGH 83
Cdd:pfam00316   2 TLTRFIIEQQHeFPNATGELTTLLSAIQLAAKFISRDIRKAGLVNLLGLAGAENVQGDQQKKLDVLADELLKNALKASGI 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244   84 LAGMASEEMDNAyQIPGKYPKGAYLLVFDPLDGSSNIDINAPVGTIFSVLRCPNEyltQNEPLNEKAFLQPGAQQVAAGY 163
Cdd:pfam00316  82 VKVLVSEEEEEL-IVFEPPKRGKYVVCFDPLDGSSNIDVNVSVGTIFSIYRRVSP---TDSPTTIEDVLQPGNEQVAAGY 157
                         170       180       190
                  ....*....|....*....|....*....|....
gi 495316244  164 AIYGPQTMLVLTLGNGVKGFTLDREMGSFVLTHE 197
Cdd:pfam00316 158 AMYGSSTMLVLTTGCGVHGFTLDPSLGEFILTHE 191
PLN02462 PLN02462
sedoheptulose-1,7-bisphosphatase
23-329 1.79e-47

sedoheptulose-1,7-bisphosphatase


Pssm-ID: 215256 [Multi-domain]  Cd Length: 304  Bit Score: 162.21  E-value: 1.79e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244  23 LRFLIEVVARACKEISHAVsKGALGGVLGSMgteNVQGEVQKKLDVMSNDILLEANEWGGHLAGMASEEMDNAYQIPGKy 102
Cdd:PLN02462  15 LRRLIMCMGEACRTIAFKV-RTASCTGTACV---NSFGDEQLAVDMLADKLLFEALKYSHVCKYACSEEVPEVQDMGGP- 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244 103 PKGAYLLVFDPLDGSSNIDINAPVGTIFSVLrcPNEYLTQneplnekaflQPGAQQVAAGYAIYGPQTMLVLTL--GNGV 180
Cdd:PLN02462  90 VEGGFSVAFDPLDGSSIVDTNFAVGTIFGVW--PGDKLTG----------VTGRDQVAAAMGIYGPRTTYVVALkdGPGT 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244 181 KGFTLDREmGSFVLTHEDITIPEStQEFAinASNQR------HWEAPVQRYVSEllagdegplkkNYNMRWVAAMVADVH 254
Cdd:PLN02462 158 HEFLLLDD-GKWQHVKETTEIGEG-KIFS--PGNLRatfdnpGYEKLINYYVSE-----------KYTLRYTGGMVPDVY 222
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 495316244 255 RILTR-GGLFMYPRdsrEPSKPGKLRLMYEANPMSFLVEQAGGASTDGHQR--ILDIQPEGLHQRVAVFLGSKEEVAR 329
Cdd:PLN02462 223 QIIVKeKGVFTNVT---SPKSKAKLRLLFEVAPLGLLVEKAGGKSSDGVQGgsVLDKQINNLDQRTQVAYGSKNEVIR 297
Arch_FBPase_2 cd01642
Putative fructose-1,6-bisphosphatase or related enzymes of inositol monophosphatase family. ...
26-119 4.00e-03

Putative fructose-1,6-bisphosphatase or related enzymes of inositol monophosphatase family. These are Mg++ dependent phosphatases. Members in this family may have fructose-1,6-bisphosphatase and/or inositol-monophosphatase activity. Fructose-1,6-bisphosphatase catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway.


Pssm-ID: 238820 [Multi-domain]  Cd Length: 244  Bit Score: 38.20  E-value: 4.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244  26 LIEVVARACKEISHAVSKGALGGVLGSMGteNVQGEVQKKLDVMSNDILLEANEWGGHLAGMASEEmdnayqiPGKYPKG 105
Cdd:cd01642    1 MLEVLEKITKEIILLLNEKNRQGLVKLIR--GAGGDVTRVADLKAEEIILKLLREEGVFGQIISEE-------SGEIRKG 71
                         90
                 ....*....|....*.
gi 495316244 106 A--YLLVFDPLDGSSN 119
Cdd:cd01642   72 SgeYIAVLDPLDGSTN 87
FIG cd01636
FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with ...
28-135 5.33e-03

FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in gluconeogenesis. Inositol-monophosphatases and inositol polyphosphatases play vital roles in eukaryotic signalling, as they participate in metabolizing the messenger molecule Inositol-1,4,5-triphosphate. Many of these enzymes are inhibited by Li+.


Pssm-ID: 238814 [Multi-domain]  Cd Length: 184  Bit Score: 37.37  E-value: 5.33e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495316244  28 EVVARACKEISHAVSKgALGGVLGSMGT-ENVQGEVQKKLDVMSNDILLEANEWGGHLAGMASEEMDNAYQIPGkyPKGA 106
Cdd:cd01636    2 EELCRVAKEAGLAILK-AFGRELSGKVKiTKSDNDPVTTADVAAETLIRNMLKSSFPDVKIVGEESGVAEEVMG--RRDE 78
                         90       100       110
                 ....*....|....*....|....*....|
gi 495316244 107 YLLVFDPLDGSSNIDINAP-VGTIFSVLRC 135
Cdd:cd01636   79 YTWVIDPIDGTKNFINGLPfVAVVIAVYVI 108
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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