|
Name |
Accession |
Description |
Interval |
E-value |
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
31-431 |
3.61e-102 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 310.36 E-value: 3.61e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 31 ALFYIGEGVITFSLVFLVYFYRKVVKPLDIIGNGMELLREQDFSSRLTPVGQKEADRIVLVFNRMMEQLKDERLRLREQN 110
Cdd:COG5000 10 LLLLIALLLLLLALWLALLLARRLTRPLRRLAEATRAVAAGDLSVRLPVTGDDEIGELARAFNRMTDQLKEQREELEERR 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 111 HFLDLLVSASPMGVVILTLDGHISMLNAAALRFLDYSsAEEVRGRLLCELA--SPLAEEIERIPKDTTE---TIRLSDSM 185
Cdd:COG5000 90 RYLETILENLPAGVIVLDADGRITLANPAAERLLGIP-LEELIGKPLEELLpeLDLAELLREALERGWQeeiELTRDGRR 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 186 IYRCSRLSFVDRGFshpFILVESLTSEVVKAEKKAYEKVIRMIAHEVNNTTAGITSTLDTVDGAL--ECMEDTEDLREVM 263
Cdd:COG5000 169 TLLVRASPLRDDGY---VIVFDDITELLRAERLAAWGELARRIAHEIKNPLTPIQLSAERLRRKLadKLEEDREDLERAL 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 264 KVCIERCYSMSRFITNFANVVKIPEPQLQSVDLNDRVAACKTFMETVCRNRKITLHLDLCKENPEVMMDTSLFEQVLVNI 343
Cdd:COG5000 246 DTIIRQVDRLKRIVDEFLDFARLPEPQLEPVDLNELLREVLALYEPALKEKDIRLELDLDPDLPEVLADRDQLEQVLINL 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 344 IKNAAESIGETGDIFIRTSVSPTM--LEIADTGAGISKEVETKLFSPFFSTKPNGQGIGLIFIREVLIKHGCTFSLRTYP 421
Cdd:COG5000 326 LKNAIEAIEEGGEIEVSTRREDGRvrIEVSDNGPGIPEEVLERIFEPFFTTKPKGTGLGLAIVKKIVEEHGGTIELESRP 405
|
410
....*....|
gi 495112460 422 DKLTRFRIRF 431
Cdd:COG5000 406 GGGTTFTIRL 415
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
105-431 |
1.28e-49 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 171.95 E-value: 1.28e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 105 RLREQNHFLDLLVSASPMGVVILTLDGHISMLNAAALRFLDYSsAEEVRGRLLCEL---ASPLAEEIERIPKDTTE---- 177
Cdd:COG3852 1 ALRESEELLRAILDSLPDAVIVLDADGRITYVNPAAERLLGLS-AEELLGRPLAELfpeDSPLRELLERALAEGQPvter 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 178 --TIRLSDSMIYRCS-RLSFVDRGFSHPFILVES--------LTSEVVKAEK-KAYEKVIRMIAHEVNNTTAGITstldt 245
Cdd:COG3852 80 evTLRRKDGEERPVDvSVSPLRDAEGEGGVLLVLrditerkrLERELRRAEKlAAVGELAAGLAHEIRNPLTGIR----- 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 246 vdGALECME---DTEDLREVMKVCIERCYSMSRFITNFANVVKIPEPQLQSVDLNDRVAACKTFMETVCRnRKITLHLDL 322
Cdd:COG3852 155 --GAAQLLErelPDDELREYTQLIIEEADRLNNLVDRLLSFSRPRPPEREPVNLHEVLERVLELLRAEAP-KNIRIVRDY 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 323 CKENPEVMMDTSLFEQVLVNIIKNAAESIGETGDIFIRTSVSPTM------------LEIADTGAGISKEVETKLFSPFF 390
Cdd:COG3852 232 DPSLPEVLGDPDQLIQVLLNLVRNAAEAMPEGGTITIRTRVERQVtlgglrprlyvrIEVIDNGPGIPEEILDRIFEPFF 311
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 495112460 391 STKPNGQGIGLIFIREVLIKHGCTFSLRTYPDKLTRFRIRF 431
Cdd:COG3852 312 TTKEKGTGLGLAIVQKIVEQHGGTIEVESEPGKGTTFRIYL 352
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
101-431 |
3.60e-42 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 152.26 E-value: 3.60e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 101 DERLRLREQNHFLDLLVSASPMGVVILTLDGHISMLNAAALRFLDYSSAEEVRGRLLCELASPLAEEIERIPKDTTETIR 180
Cdd:COG4191 7 LLLLLLALLRALALALALLLLLLLLLLALLLLLLALLLALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLLLLGLLL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 181 LSDSMIYRCSRLSFVDRGFSHPFILVESLTSEVVKAE---KKAYEKVIRM------------IAHEVNNTTAGITSTLDT 245
Cdd:COG4191 87 LLLLEALLLLLLAALDAEENAELEELERDITELERAEeelRELQEQLVQSeklaalgelaagIAHEINNPLAAILGNAEL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 246 VDGALECMEDTEDLREVMKVCIERCYSMSRFITNFANVVKIPEPQLQSVDLNDRVAACKTFMETVCRNRKITLHLDLCKE 325
Cdd:COG4191 167 LRRRLEDEPDPEELREALERILEGAERAAEIVRSLRAFSRRDEEEREPVDLNELIDEALELLRPRLKARGIEVELDLPPD 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 326 NPEVMMDTSLFEQVLVNIIKNAAESIGET--GDIFIRTSVSPTM--LEIADTGAGISKEVETKLFSPFFSTKPNGQGIGL 401
Cdd:COG4191 247 LPPVLGDPGQLEQVLLNLLINAIDAMEEGegGRITISTRREGDYvvISVRDNGPGIPPEVLERIFEPFFTTKPVGKGTGL 326
|
330 340 350
....*....|....*....|....*....|...
gi 495112460 402 ---IfIREVLIKHGCTFSLRTYPDKLTRFRIRF 431
Cdd:COG4191 327 glsI-SYGIVEKHGGRIEVESEPGGGTTFTITL 358
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
28-431 |
1.57e-34 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 135.48 E-value: 1.57e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 28 ERGALFYIGEG-VITFSLVFLvyFYRKVVKPLDIIGNGMELLrEQDFSSRLTPVgQKEADRIVLVFNRMMEqlkderlRL 106
Cdd:PRK11360 189 DRRIYAVLAAGlVIGLLLIFL--LSRRFSANVDIIKDGLSTL-ENDLSTRLPPL-PGELGEISQAINNLAQ-------AL 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 107 REQNHFLDLLVSASPMGVVILTLDGHISMLNAAALRFLDYSSAEeVRGRLLCEL---ASPLAEEIERIPKDTTE------ 177
Cdd:PRK11360 258 RETRSLNELILESIADGVIAIDRQGKITTMNPAAEVITGLQRHE-LVGKPYSELfppNTPFASPLLDTLEHGTEhvdlei 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 178 -------TIRLSDSmiyrCSRLSFVDRGFSHPFILVESLTsevvkAEKKAYEKVIRM------------IAHEVNNTtag 238
Cdd:PRK11360 337 sfpgrdrTIELSVS----TSLLHNTHGEMIGALVIFSDLT-----ERKRLQRRVARQerlaalgelvagVAHEIRNP--- 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 239 ITSTLDTVDGALECMEDTEDlREVMKVCIERCYSMSRFITNFANVVKIPEPQLQSVDLNDRVAACKTFMETVCRNRKITL 318
Cdd:PRK11360 405 LTAIRGYVQIWRQQTSDPPS-QEYLSVVLREVDRLNKVIDQLLEFSRPRESQWQPVSLNALVEEVLQLFQTAGVQARVDF 483
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 319 HLDLCKENPEVMMDTSLFEQVLVNIIKNAAESIGETGDIFIRTSVSPT---MLEIADTGAGISKEVETKLFSPFFSTKPN 395
Cdd:PRK11360 484 ETELDNELPPIWADPELLKQVLLNILINAVQAISARGKIRIRTWQYSDgqvAVSIEDNGCGIDPELLKKIFDPFFTTKAK 563
|
410 420 430
....*....|....*....|....*....|....*.
gi 495112460 396 GQGIGLIFIREVLIKHGCTFSLRTYPDKLTRFRIRF 431
Cdd:PRK11360 564 GTGLGLALSQRIINAHGGDIEVESEPGVGTTFTLYL 599
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
69-431 |
7.05e-31 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 124.07 E-value: 7.05e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 69 REQDFSSRLTPVGQKEADRIVLVFnRMMEQLKDERLRLREQNHFLDLLVSASPMGVVILTLDGHISMLNAAALRFLDYSs 148
Cdd:COG5805 116 ELIYVEVKLFPIYNQNGQAAILAL-RDITKKKKIEEILQEQEERLQTLIENSPDLICVIDTDGRILFINESIERLFGAP- 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 149 AEEVRGRLLCELASP-LAEEI-ERIPKDT---------TETIRLSDSMIY-RCSRLSFVDRGFSHPFILVeslTSEVVKA 216
Cdd:COG5805 194 REELIGKNLLELLHPcDKEEFkERIESITevwqefiieREIITKDGRIRYfEAVIVPLIDTDGSVKGILV---ILRDITE 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 217 EKKAYEKVIRM------------IAHEVNNTtagitstLDTVDGALECM----EDTEDLREVMKVCIERcysMSRFITNF 280
Cdd:COG5805 271 KKEAEELMARSeklsiagqlaagIAHEIRNP-------LTSIKGFLQLLqpgiEDKEEYFDIMLSELDR---IESIISEF 340
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 281 ANVVKIPEPQLQSVDLNDRVAACKTFMETVCRNRKITLHLDLCKENPEVMMDTSLFEQVLVNIIKNAAESIGETGDIFIR 360
Cdd:COG5805 341 LALAKPQAVNKEKENINELIQDVVTLLETEAILHNIQIRLELLDEDPFIYCDENQIKQVFINLIKNAIEAMPNGGTITIH 420
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 495112460 361 TSV--SPTMLEIADTGAGISKEVETKLFSPFFSTKPNGQGIGLIFIREVLIKHGCTFSLRTYPDKLTRFRIRF 431
Cdd:COG5805 421 TEEedNSVIIRVIDEGIGIPEERLKKLGEPFFTTKEKGTGLGLMVSYKIIENHNGTIDIDSKVGKGTTFTITL 493
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
115-431 |
6.08e-30 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 118.47 E-value: 6.08e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 115 LLVSASPMGVVILTLDGHISMLNAAALRFLDYSSAEEVRGRLLCELASPLAEEIERIPKDTTETIRLSDSMIYRCSRLSF 194
Cdd:COG0642 2 LLLLLLLVLLLLLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 195 VDRGFSHPFILVESLTSEVVKAEK--KAYEKVIRMIAHEVNNTTAGITSTLDTVDgalecMEDTEDLREVMKVCIERCYS 272
Cdd:COG0642 82 LLLLLLLLLLLLLLLLALLLLLEEanEAKSRFLANVSHELRTPLTAIRGYLELLL-----EELDEEQREYLETILRSADR 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 273 MSRFITNFANVVKI----PEPQLQSVDLNDRVAACKTFMETVCRNRKITLHLDLCKENPEVMMDTSLFEQVLVNIIKNAA 348
Cdd:COG0642 157 LLRLINDLLDLSRLeagkLELEPEPVDLAELLEEVVELFRPLAEEKGIELELDLPDDLPTVRGDPDRLRQVLLNLLSNAI 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 349 ESIGETGDIFIRTSVSPTM--LEIADTGAGISKEVETKLFSPFFSTKP----NGQGIGLIFIREVLIKHGCTFSLRTYPD 422
Cdd:COG0642 237 KYTPEGGTVTVSVRREGDRvrISVEDTGPGIPPEDLERIFEPFFRTDPsrrgGGTGLGLAIVKRIVELHGGTIEVESEPG 316
|
....*....
gi 495112460 423 KLTRFRIRF 431
Cdd:COG0642 317 KGTTFTVTL 325
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
225-431 |
3.36e-27 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 108.46 E-value: 3.36e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 225 IRMIAHEVNNTTAGITSTLDTVDGALEcmEDTEDLREVMKVCIERCYSMSRFITNFANVVKI----PEPQLQSVDLNDRV 300
Cdd:COG2205 20 LANVSHELRTPLTSILGAAELLLDEED--LSPEERRELLEIIRESAERLLRLIEDLLDLSRLesgkLSLELEPVDLAELL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 301 AACKTFMETVCRNRKITLHLDLCKENPEVMMDTSLFEQVLVNIIKNAAESIGETGDIFIRTSVSPTM--LEIADTGAGIS 378
Cdd:COG2205 98 EEAVEELRPLAEEKGIRLELDLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTITISARREGDGvrISVSDNGPGIP 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 495112460 379 KEVETKLFSPFF----STKPNGQGIGLIFIREVLIKHGCTFSLRTYPDKLTRFRIRF 431
Cdd:COG2205 178 EEELERIFERFYrgdnSRGEGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVTL 234
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
72-401 |
9.72e-26 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 108.91 E-value: 9.72e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 72 DFSSRLTPVGQKEADRIVLVF-NRMMEQLKDERLRLREQNHFLDLLVSASPMGVVILTLDGHISMLNAAALRFLDYSSaE 150
Cdd:COG5809 101 EFSSKLSPIFDQNGDIEGMLAiSRDITERKRMEEALRESEEKFRLIFNHSPDGIIVTDLDGRIIYANPAACKLLGISI-E 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 151 EVRGRLLCELASP--LAEEIERI--------PKDTTETIRLSD--SMIYRCSRLSFVDRGFSHPFILV-ESLTsevvkaE 217
Cdd:COG5809 180 ELIGKSILELIHSddQENVAAFIsqllkdggIAQGEVRFWTKDgrWRLLEASGAPIKKNGEVDGIVIIfRDIT------E 253
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 218 KKAYEKVIR-------------MIAHEVNNTtagitstLDTVDGALECMEDTEDLR-----EVMKVCIERcysMSRFITN 279
Cdd:COG5809 254 RKKLEELLRkseklsvvgelaaGIAHEIRNP-------LTSLKGFIQLLKDTIDEEqktylDIMLSELDR---IESIISE 323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 280 FANVVKIPEPQLQSVDLNDRVAACKTFMETVCRNRKITLHLDLCKENPEVMMDTSLFEQVLVNIIKNAAESIGETGDIFI 359
Cdd:COG5809 324 FLVLAKPQAIKYEPKDLNTLIEEVIPLLQPQALLKNVQIELELEDDIPDILGDENQLKQVFINLLKNAIEAMPEGGNITI 403
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 495112460 360 RTSVSP---TMLEIADTGAGISKEVETKLFSPFFSTKPNGQGIGL 401
Cdd:COG5809 404 ETKAEDddkVVISVTDEGCGIPEERLKKLGEPFYTTKEKGTGLGL 448
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
87-431 |
4.45e-22 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 97.32 E-value: 4.45e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 87 RIVLVFNRMMEQLKDERLRLREQNHFLDLLVSASPMGVVILTLDGHISMLNAAALRFLDYSSAEEVRGRLLCELASPLAE 166
Cdd:COG5002 37 LLLLLLLLLLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAA 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 167 EIERIPKDTTETIRLSDSMIYRcsrlsFVDRGFSHPFILVESLTSEVVKAEKkAYEKVIRMIAHEVNNTTAGITSTLDTV 246
Cdd:COG5002 117 LLLLLSELLLLLLLLGRLSLRL-----SALLLGLLLLAAVERDITELERLEQ-MRREFVANVSHELRTPLTSIRGYLELL 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 247 -DGAlecMEDTEDLREVMKVCIERCYSMSRFITNFANVVKI----PEPQLQSVDLNDRVAACKTFMETVCRNRKITLHLD 321
Cdd:COG5002 191 lDGA---ADDPEERREYLEIILEEAERLSRLVNDLLDLSRLesgeLKLEKEPVDLAELLEEVVEELRPLAEEKGIELELD 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 322 LCKENPEVMMDTSLFEQVLVNIIKNAAESIGETGDIFIRTSVSPTM--LEIADTGAGISKEVETKLFSPFF------STK 393
Cdd:COG5002 268 LPEDPLLVLGDPDRLEQVLTNLLDNAIKYTPEGGTITVSLREEDDQvrISVRDTGIGIPEEDLPRIFERFYrvdksrSRE 347
|
330 340 350
....*....|....*....|....*....|....*...
gi 495112460 394 PNGQGIGLIFIREVLIKHGCTFSLRTYPDKLTRFRIRF 431
Cdd:COG5002 348 TGGTGLGLAIVKHIVEAHGGRIWVESEPGKGTTFTITL 385
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
32-431 |
5.62e-21 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 94.14 E-value: 5.62e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 32 LFYIGEGVITFSLVFLVYFYRKVVKPLDIIGNGMELLreqdFSSRLTPVGQKEADRIVLVFNRMMEQLKDERLRLREQNh 111
Cdd:COG3290 12 LILLILILILLLLLLIILLLILLLVLLLLLFLLFVII----LLLLLLILLLILLLLLLLLLAALLLKLLEEIARLVEER- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 112 flDLLVSASPMGVVILTLDGHISMLNAAALRFLDYssaeEVRGRLLCELASPLAEEIERipkdttETIRLSDSMIYRCSR 191
Cdd:COG3290 87 --EAVLESIREGVIAVDRDGRITLINDAARRLLGL----DAIGRPIDEVLAEVLETGER------DEEILLNGRVLVVNR 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 192 LSFVDRGFSHPFILVESLTSEVVKAEK-----KAYEKVIRMIAHEVNNTtagitstLDTVDGALEcMEDTEDLREVMKVC 266
Cdd:COG3290 155 VPIRDDGRVVGAVATFRDRTELERLEEelegvKELAEALRAQRHDFRNH-------LHTISGLLQ-LGEYDEALEYIDEI 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 267 IERCYSMSRFItnfanVVKIPEPQLQSVdLNDRVAacktfmetVCRNRKITLHLDLCKENPEVMMDTSLFEQVLVNIIKN 346
Cdd:COG3290 227 SEELQELIDSL-----LSRIGNPVLAAL-LLGKAA--------RARERGIDLTIDIDSDLPDLPLSDTDLVTILGNLLDN 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 347 AAESI--GETGDIFIRTSVSPT----MLEIADTGAGISKEVETKLFSPFFSTKP-NGQGIGLIFIREVLIKHGCTFSLRT 419
Cdd:COG3290 293 AIEAVekLPEEERRVELSIRDDgdelVIEVEDSGPGIPEELLEKIFERGFSTKLgEGRGLGLALVKQIVEKYGGTIEVES 372
|
410
....*....|..
gi 495112460 420 YPDKLTRFRIRF 431
Cdd:COG3290 373 EEGEGTVFTVRL 384
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
216-429 |
1.35e-20 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 93.70 E-value: 1.35e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 216 AEKKAYEKVIRM------IAHEVNNTTAGITStLDTVDGAlECMEDTEDlREVMKVCIERCYSMSRFITNFANVVKIPEP 289
Cdd:PRK10364 226 DEMKRKEKLVALghlaagVAHEIRNPLSSIKG-LAKYFAE-RAPAGGEA-HQLAQVMAKEADRLNRVVSELLELVKPTHL 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 290 QLQSVDLNDRVAACKTFMETVCRNRKITLHLDLCKENPEVMMDTSLFEQVLVNIIKNAAESIGETGDIFIRTSVSPTMLE 369
Cdd:PRK10364 303 ALQAVDLNDLINHSLQLVSQDANSREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVK 382
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 495112460 370 I--ADTGAGISKEVETKLFSPFFSTKPNGQGIGLIFIREVLIKHGCTFSLRTYPDKLTRFRI 429
Cdd:PRK10364 383 IsvTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTL 444
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
334-429 |
1.40e-20 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 86.32 E-value: 1.40e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 334 SLFEQVLVNIIKNAAESIGETGDIFIRT--SVSPTMLEIADTGAGISKEVETKLFSPFFSTKPNGQ--GIGLIFIREVLI 409
Cdd:cd16943 2 SQLNQVLLNLLVNAAQAMEGRGRITIRTwaHVDQVLIEVEDTGSGIDPEILGRIFDPFFTTKPVGEgtGLGLSLSYRIIQ 81
|
90 100
....*....|....*....|
gi 495112460 410 KHGCTFSLRTYPDKLTRFRI 429
Cdd:cd16943 82 KHGGTIRVASVPGGGTRFTI 101
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
331-431 |
6.74e-17 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 76.15 E-value: 6.74e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 331 MDTSLFEQVLVNIIKNAAESIGETGDIFIRTSVSPTM--LEIADTGAGISKEVETKLFSPFFSTKPN-----GQGIGLIF 403
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHveITVEDNGPGIPPEDLEKIFEPFFRTDKRsrkigGTGLGLSI 80
|
90 100
....*....|....*....|....*...
gi 495112460 404 IREVLIKHGCTFSLRTYPDKLTRFRIRF 431
Cdd:smart00387 81 VKKLVELHGGEISVESEPGGGTTFTITL 108
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
337-412 |
1.50e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 72.04 E-value: 1.50e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 337 EQVLVNIIKNAAESIG----ETGDIFIRTSVS-PTMLEIA--DTGAGISKEVETKLFSPFFSTKPNGQGIGLIFIREVLI 409
Cdd:cd16920 2 QQVLINLVRNGIEAMSeggcERRELTIRTSPAdDRAVTISvkDTGPGIAEEVAGQLFDPFYTTKSEGLGMGLSICRSIIE 81
|
...
gi 495112460 410 KHG 412
Cdd:cd16920 82 AHG 84
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
337-429 |
3.95e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 70.89 E-value: 3.95e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 337 EQVLVNIIKNAAESIGET-GDIFIRTSVS------------PTMLEIADTGAGISKEVETKLFSPFFSTKPNGQGIGLIF 403
Cdd:cd16918 2 IQVFLNLVRNAAQALAGSgGEIILRTRTQrqvtlghprhrlALRVSVIDNGPGIPPDLQDTIFYPMVSGRENGTGLGLAI 81
|
90 100
....*....|....*....|....*.
gi 495112460 404 IREVLIKHGCTFSLRTYPDKlTRFRI 429
Cdd:cd16918 82 AQNIVSQHGGVIECDSQPGH-TVFSV 106
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
228-412 |
1.26e-14 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 75.88 E-value: 1.26e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 228 IAHEVNNTTAGITSTLDTVDGALEcMEDTEDLR---EVMKVCIERcysMSRFITNFANVVKIPEPQLQSVDLNDRVAACK 304
Cdd:COG4192 440 LAHELNQPLNAMSMYLFSAKKALE-QENYAQLPtslDKIEGLIER---MDKIIKSLRQFSRKSDTPLQPVDLRQVIEQAW 515
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 305 TFMETVCRNRKITLHLdlcKENPEVMMDTSLFEQVLVNIIKNAAESIGETGDIFIRTSVSPTMLEIADTGAGISKEVETK 384
Cdd:COG4192 516 ELVESRAKPQQITLHI---PDDLMVQGDQVLLEQVLVNLLVNALDAVATQPQISVDLLSNAENLRVAISDNGNGWPLVDK 592
|
170 180
....*....|....*....|....*...
gi 495112460 385 LFSPFFSTKPNGQGIGLIFIREVLIKHG 412
Cdd:COG4192 593 LFTPFTTTKEVGLGLGLSICRSIMQQFG 620
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
331-431 |
8.29e-14 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 67.39 E-value: 8.29e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 331 MDTSLFEQVLVNIIKNAAESIGETGDIFIRTSVSPT-MLEIADTGAGISKEVETKLFSPFFS---TKPNGQGIGLIFIRE 406
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGEITVTLSEGGElTLTVEDNGIGIPPEDLPRIFEPFSTadkRGGGGTGLGLSIVRK 80
|
90 100
....*....|....*....|....*
gi 495112460 407 VLIKHGCTFSLRTYPDKLTRFRIRF 431
Cdd:pfam02518 81 LVELLGGTITVESEPGGGTTVTLTL 105
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
106-429 |
8.59e-14 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 72.04 E-value: 8.59e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 106 LREQNHFLDLLVSAspmgvvILTLDGH--ISMLNAAALRFLDYSsAEEVRGRLLCELASPLAEEIE--RIPKDTTETIRL 181
Cdd:PRK11073 6 LPDAGQILNSLINS------ILLLDDDlaIHYANPAAQQLLAQS-SRKLFGTPLPELLSYFSLNIElmRESLQAGQGFTD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 182 SDSMIYRCSR---LSFVDRGFSHPFILVE--------SLTSEVVK-AEKKAYEKVIRMIAHEVNNTTAGITstldtvdGA 249
Cdd:PRK11073 79 NEVTLVIDGRshiLSLTAQRLPEGMILLEmapmdnqrRLSQEQLQhAQQVAARDLVRGLAHEIKNPLGGLR-------GA 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 250 ---LECMEDTEDLREVMKVCIERCYSMSRFITNFANVVKIPEPQLQSVDlndRVAacktfmETVCR------NRKITLHL 320
Cdd:PRK11073 152 aqlLSKALPDPALTEYTKVIIEQADRLRNLVDRLLGPQRPGTHVTESIH---KVA------ERVVQlvslelPDNVRLIR 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 321 DLCKENPEVMMDTSLFEQVLVNIIKNAAESIGET-GDIFIRTSVS------------PTMLEIADTGAGISKEVETKLFS 387
Cdd:PRK11073 223 DYDPSLPELAHDPDQIEQVLLNIVRNALQALGPEgGTITLRTRTAfqltlhgeryrlAARIDIEDNGPGIPPHLQDTLFY 302
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 495112460 388 PFFSTKPNGQGIGLIFIREVLIKHGCTFSLRTYPDKlTRFRI 429
Cdd:PRK11073 303 PMVSGREGGTGLGLSIARNLIDQHSGKIEFTSWPGH-TEFSV 343
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
211-401 |
8.99e-14 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 72.59 E-value: 8.99e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 211 SEVVKAEKkaYEKVIRM---IAHEVNNTtagitstLDTVDG----ALECMEDTEDLREVMKVCIERCYSMSRFITNFANV 283
Cdd:COG5806 190 KELQRAEK--LEVVSELaasIAHEVRNP-------LTVVRGfiqlLQEPELSDEKRKQYIRIALEELDRAEAIITDYLTF 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 284 VKiPEP-QLQSVDLNDRVAACKTFMETVCRNRKITLHLDlCKENPEVMMDTSLFEQVLVNIIKNAAESIGETGDIFIRTS 362
Cdd:COG5806 261 AK-PQPeKLEKIDVSEELEHVIDVLSPYANMNNVEIQTE-LEPGLYIEGDRQKLQQCLINIIKNGIEAMPNGGTLTIDVS 338
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 495112460 363 VSP--TMLEIADTGAGISKEVETKLFSPFFSTKPNGQGIGL 401
Cdd:COG5806 339 IDKnkVIISIKDTGVGMTKEQLERLGEPYFSTKEKGTGLGT 379
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
314-429 |
2.28e-13 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 72.02 E-value: 2.28e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 314 RKITLHLDLCKENPEVMMDTSLFEQVLVNIIKNAAESIGETGDIFIRTSVSP-----------------TMLEIADTGAG 376
Cdd:PRK13837 539 PGVELDFDQDQEPAVVEGNPAELQQVLMNLCSNAAQAMDGAGRVDISLSRAKlrapkvlshgvlppgryVLLRVSDTGAG 618
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 495112460 377 ISKEVETKLFSPFFSTKPNGQGIGLIFIREVLIKHGCTFSLRTYPDKLTRFRI 429
Cdd:PRK13837 619 IDEAVLPHIFEPFFTTRAGGTGLGLATVHGIVSAHAGYIDVQSTVGRGTRFDV 671
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
332-431 |
6.78e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 64.87 E-value: 6.78e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 332 DTSLFEQVLVNIIKNAAESIGET----GDIFIRTS---VSPTMLEIADTGAGISKEVETKLFSPFFSTKPNGQGIGLIFI 404
Cdd:cd16944 1 DTTQISQVLTNILKNAAEAIEGRpsdvGEVRIRVEadqDGRIVLIVCDNGKGFPREMRHRATEPYVTTRPKGTGLGLAIV 80
|
90 100
....*....|....*....|....*..
gi 495112460 405 REVLIKHGCTFSLRTYPDKLTRFRIRF 431
Cdd:cd16944 81 KKIMEEHGGRISLSNREAGGACIRIIL 107
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
336-431 |
6.84e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 65.09 E-value: 6.84e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 336 FEQVLVNIIKNAAESIGETGDIFIRTSVSP-----------------TMLEIADTGAGISKEVETKLFSPFFSTKPNGQG 398
Cdd:cd16919 1 LELAILNLAVNARDAMPEGGRLTIETSNQRvdadyalnyrdlipgnyVCLEVSDTGSGMPAEVLRRAFEPFFTTKEVGKG 80
|
90 100 110
....*....|....*....|....*....|....*
gi 495112460 399 IGL-IFIREVLIKH-GCTFSLRTYPDKLTRFRIRF 431
Cdd:cd16919 81 TGLgLSMVYGFVKQsGGHLRIYSEPGVGTTVRIYL 115
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
337-429 |
2.02e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 63.24 E-value: 2.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 337 EQVLVNIIKNAAESIGETGDIFIRTSV----SPTMLEIADTGAGISKEVETKLFSPFFSTKPNGQGIGL-IFIREVLI-K 410
Cdd:cd16976 2 QQVLMNLLQNALDAMGKVENPRIRIAArrlgGRLVLVVRDNGPGIAEEHLSRVFDPFFTTKPVGKGTGLgLSISYGIVeE 81
|
90
....*....|....*....
gi 495112460 411 HGCTFSLRTYPDKLTRFRI 429
Cdd:cd16976 82 HGGRLSVANEEGAGARFTF 100
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
155-412 |
3.31e-12 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 67.67 E-value: 3.31e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 155 RLLCELASPLAEEIERIP------KDTTETIRLSDSMiyrcsrlsfvdrgfshpFILV---ESLTSEVvkaekKAYEKVI 225
Cdd:PRK09303 98 RWQQEGATYSGLGENLQPseidsgRYSQELLQLSDEL-----------------FVLRqenETLLEQL-----KFKDRVL 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 226 RMIAHEVNN--TTAGITstLDTVDGALE------CMEDTEDLREVMKvciERCYSMSRFITNFANVVKIPEPQL----QS 293
Cdd:PRK09303 156 AMLAHDLRTplTAASLA--LETLELGQIdedtelKPALIEQLQDQAR---RQLEEIERLITDLLEVGRTRWEALrfnpQK 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 294 VDLNDRVAACKTFMETVCRNRKITLHLDLCKENPEVMMDTSLFEQVLVNIIKNAAESIGETGDIFI----RTS----VSp 365
Cdd:PRK09303 231 LDLGSLCQEVILELEKRWLAKSLEIQTDIPSDLPSVYADQERIRQVLLNLLDNAIKYTPEGGTITLsmlhRTTqkvqVS- 309
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 495112460 366 tmleIADTGAGISKEVETKLFSPFF----STKPNGQGIGLIFIREVLIKHG 412
Cdd:PRK09303 310 ----ICDTGPGIPEEEQERIFEDRVrlprDEGTEGYGIGLSVCRRIVRVHY 356
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
257-431 |
2.85e-11 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 65.19 E-value: 2.85e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 257 EDLREVMKVCIERCYSMSRFIT---NFANVVKIPEPqLQSVDLNDRVAACKTFMETVCRNRKITLHLDlckENPEVMMDT 333
Cdd:COG4251 317 EEGREYLERIRDAAERMQALIDdllAYSRVGRQELE-FEPVDLNELLEEVLEDLEPRIEERGAEIEVG---PLPTVRGDP 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 334 SLFEQVLVNIIKNAAE--SIGETGDIFIRTSVSPTM--LEIADTGAGISKEVETKLFSPFF----STKPNGQGIGLIFIR 405
Cdd:COG4251 393 TLLRQVFQNLISNAIKysRPGEPPRIEIGAEREGGEwvFSVRDNGIGIDPEYAEKIFEIFQrlhsRDEYEGTGIGLAIVK 472
|
170 180
....*....|....*....|....*.
gi 495112460 406 EVLIKHGCTFSLRTYPDKLTRFRIRF 431
Cdd:COG4251 473 KIVERHGGRIWVESEPGEGATFYFTL 498
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
342-430 |
3.01e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 54.22 E-value: 3.01e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 342 NIIKNAAESIGETGD------IFIRTSVSPTMLEIADTGAGISKEVETKLFSPFFSTKPNG-QGIGLIFIREVLIKHGCT 414
Cdd:cd16915 7 NLIDNALDALAATGApnkqveVFLRDEGDDLVIEVRDTGPGIAPELRDKVFERGVSTKGQGeRGIGLALVRQSVERLGGS 86
|
90
....*....|....*.
gi 495112460 415 FSLRTYPDKLTRFRIR 430
Cdd:cd16915 87 ITVESEPGGGTTFSIR 102
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
317-429 |
5.94e-09 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 58.12 E-value: 5.94e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 317 TLHLDLCKENPEVMMDTSLFEQVLVNIIKNAAESIGETGDIFIRTSVSPTMLEIA--DTGAGISKEVETKLFSPFF---- 390
Cdd:PRK10490 760 PINLSLPEPLTLIHVDGPLFERVLINLLENAVKYAGAQAEIGIDAHVEGERLQLDvwDNGPGIPPGQEQLIFDKFArgnk 839
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 495112460 391 -STKPnGQGIGLIFIREVLIKHGCTFSLRTYPDKLTRFRI 429
Cdd:PRK10490 840 eSAIP-GVGLGLAICRAIVEVHGGTIWAENRPEGGACFRV 878
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
228-401 |
8.45e-09 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 57.37 E-value: 8.45e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 228 IAHEVNNTTAGITSTLDTVDGALECME-DTEDLR---EVMKVCIERCYSMSRFITNFANVVKIpepQLQSVDLNDRVA-- 301
Cdd:PRK13557 170 IAHDFNNLLQVMSGYLDVIQAALSHPDaDRGRMArsvENIRAAAERAATLTQQLLAFARKQRL---EGRVLNLNGLVSgm 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 302 ---ACKTFMETvcrnrkITLHLDLCKENPEVMMDTSLFEQVLVNIIKNAAESIGETGDIFIRT-SVSPTMLEIA------ 371
Cdd:PRK13557 247 gelAERTLGDA------VTIETDLAPDLWNCRIDPTQAEVALLNVLINARDAMPEGGRVTIRTrNVEIEDEDLAmyhglp 320
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 495112460 372 ----------DTGAGISKEVETKLFSPFFSTKPNGQGIGL 401
Cdd:PRK13557 321 pgryvsiavtDTGSGMPPEILARVMDPFFTTKEEGKGTGL 360
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
228-401 |
9.58e-09 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 57.73 E-value: 9.58e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 228 IAHEVNNTTAGITstldtvdGALECMEDTE------DLREVMKVCierCYSMSRFITNFANVVKIPEPQ----LQSVD-- 295
Cdd:PRK15347 405 ISHEIRTPLNGVL-------GALELLQNTPltaeqmDLADTARQC---TLSLLAIINNLLDFSRIESGQmtlsLEETAll 474
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 296 -LNDRVaacktfMETV---CRNRKITLHLDLCKENPEVM-MDTSLFEQVLVNIIKNAAEsIGETGDIFIRTSVSPTML-- 368
Cdd:PRK15347 475 pLLDQA------MLTIqgpAQSKSLTLRTFVGAHVPLYLhLDSLRLRQILVNLLGNAVK-FTETGGIRLRVKRHEQQLcf 547
|
170 180 190
....*....|....*....|....*....|...
gi 495112460 369 EIADTGAGISKEVETKLFSPFFSTKPNGQGIGL 401
Cdd:PRK15347 548 TVEDTGCGIDIQQQQQIFTPFYQADTHSQGTGL 580
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
339-430 |
1.61e-08 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 56.46 E-value: 1.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 339 VLVNIIKNAAESIG--ETGDIFIRTSVSPTML--EIADTGAGISKEVETKLFSPFFSTKPNGQGIGLIFIREVLIKHGCT 414
Cdd:PRK11086 437 ILGNLIENALEAVGgeEGGEISVSLHYRNGWLhcEVSDDGPGIAPDEIDAIFDKGYSTKGSNRGVGLYLVKQSVENLGGS 516
|
90
....*....|....*.
gi 495112460 415 FSLRTYPDKLTRFRIR 430
Cdd:PRK11086 517 IAVESEPGVGTQFFVQ 532
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
307-430 |
6.26e-08 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 54.91 E-value: 6.26e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 307 METVCRNRKITLHLDLCKENPEVMM-DTSLFEQVLVNIIKNAAEsIGETGDIFIRTSVSPT--MLEIADTGAGISKEVET 383
Cdd:PRK11466 532 MSGRVKGRPIRLATDIADDLPTALMgDPRRIRQVITNLLSNALR-FTDEGSIVLRSRTDGEqwLVEVEDSGCGIDPAKLA 610
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 495112460 384 KLFSPF--FSTKPNGQGIGLIFIREVLIKHGCTFSLRTYPDKLTRFRIR 430
Cdd:PRK11466 611 EIFQPFvqVSGKRGGTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLR 659
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
228-429 |
1.07e-07 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 54.01 E-value: 1.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 228 IAHEVNNTtagITSTLDTVDGALECMEDTEDLREVMKVCIERCYSMSRFITNFANVVKIPEPQL----QSVDLNDRVAAC 303
Cdd:PRK09835 269 IAHEIRTP---ITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQLipekKMLDLADEVGKV 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 304 KTFMETVCRNRKITLHLDlcKENPEVMMDTSLFEQVLVNIIKNAAESI--GETGDIFIRTSVSPTMLEIADTGAGISKEV 381
Cdd:PRK09835 346 FDFFEAWAEERGVELRFV--GDPCQVAGDPLMLRRAISNLLSNALRYTpaGEAITVRCQEVDHQVQLVVENPGTPIAPEH 423
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 495112460 382 ETKLFSPFFSTKPN------GQGIGLIFIREVLIKHGCTFSLRTYPDKlTRFRI 429
Cdd:PRK09835 424 LPRLFDRFYRVDPSrqrkgeGSGIGLAIVKSIVVAHKGTVAVTSDARG-TRFVI 476
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
290-431 |
1.65e-07 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 53.31 E-value: 1.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 290 QLQSVDLNDRVAACKTFMETVCRNRKITLHLDLckENPEVMMDTSLFEQVLVNIIKNAAESIGETGDIFIRTSVS--PTM 367
Cdd:PRK11100 325 VLEPVALAALLEELVEAREAQAAAKGITLRLRP--DDARVLGDPFLLRQALGNLLDNAIDFSPEGGTITLSAEVDgeQVA 402
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 495112460 368 LEIADTGAGISKEVETKLFSPFFST-KPNGQ----GIGLIFIREVLIKHGCTFSLRTYPDKLTRFRIRF 431
Cdd:PRK11100 403 LSVEDQGPGIPDYALPRIFERFYSLpRPANGrkstGLGLAFVREVARLHGGEVTLRNRPEGGVLATLTL 471
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
332-422 |
2.37e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 49.00 E-value: 2.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 332 DTSLFEQVLVNIIKNAAESIGETGDIFIRTSVSPTMLEIA--DTGAGISKEVETKLFSPFFS-TKPNGQ----GIGLIFI 404
Cdd:cd16945 1 DPFLLRQAINNLLDNAIDFSPEGGLIALQLEADTEGIELLvfDEGSGIPDYALNRVFERFYSlPRPHSGqkstGLGLAFV 80
|
90
....*....|....*...
gi 495112460 405 REVLIKHGCTFSLRTYPD 422
Cdd:cd16945 81 QEVAQLHGGRITLRNRPD 98
|
|
| PAS |
smart00091 |
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
111-171 |
3.12e-07 |
|
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels.
Pssm-ID: 214512 Cd Length: 67 Bit Score: 47.39 E-value: 3.12e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 495112460 111 HFLDLLVSASPMGVVILTLDGHISMLNAAALRFLDYsSAEEVRGRLLCELASPlaEEIERI 171
Cdd:smart00091 1 ERLRAILESLPDGIFVLDLDGRILYANPAAEELLGY-SPEELIGKSLLELIHP--EDRERV 58
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
332-416 |
1.51e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 46.69 E-value: 1.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 332 DTSLFEQVLVNIIKNAAESIGETGDIFIRTSVSPTMLEI--ADTGAGISKEVETKLFSPFFSTKPN------GQGIGLIF 403
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLdvEDSAPGVSDDQLARLFERFYRVESSrnrasgGSGLGLAI 80
|
90
....*....|...
gi 495112460 404 IREVLIKHGCTFS 416
Cdd:cd16946 81 CHNIALAHGGTIS 93
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
205-429 |
1.59e-06 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 50.50 E-value: 1.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 205 LVESLTSEVVKA--EKKAYEKVIRMIAHEVNNTTAGITSTLDTVDGAlecMEDTEDLREVMKVCIERCYSMSRFITNFAN 282
Cdd:PRK09959 694 LIHALEVERNKAinATVAKSQFLATMSHEIRTPISSIMGFLELLSGS---GLSKEQRVEAISLAYATGQSLLGLIGEILD 770
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 283 VVKIP----EPQLQSVDLNDRVA-ACKTFmETVCRNRKITLHldlCKEN-PE---VMMDTSLFEQVLVNIIKNAAESIGE 353
Cdd:PRK09959 771 VDKIEsgnyQLQPQWVDIPTLVQnTCHSF-GAIAASKSIALS---CSSTfPDhylVKIDPQAFKQVLSNLLSNALKFTTE 846
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 354 tGDIFIRTSV-------SPTMLEIADTGAGISKEVETKLFSPFFST----KPNGQGIGLIFIREVLIKHGCTFSLRTYPD 422
Cdd:PRK09959 847 -GAVKITTSLghiddnhAVIKMTIMDSGSGLSQEEQQQLFKRYSQTsagrQQTGSGLGLMICKELIKNMQGDLSLESHPG 925
|
....*..
gi 495112460 423 KLTRFRI 429
Cdd:PRK09959 926 IGTTFTI 932
|
|
| NarQ |
COG3850 |
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ... |
20-262 |
1.82e-06 |
|
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];
Pssm-ID: 443059 [Multi-domain] Cd Length: 448 Bit Score: 49.88 E-value: 1.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 20 ILLVLTLKERGALFYIGEGVITFSLVFLVYFYRKVVKPLDIIGNGMELLREQDFSSRLTPVGQKEADRIVLVFNRMMEQL 99
Cdd:COG3850 108 LLLLAAAINRKLALLRLLLALLLALLLAYLLRRRIVRPLRRLTQAAERIARGDFDARVPVSGRDELGTLARAFNRMADEL 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 100 KDERLRLREQN---HFLDLLVSASPMGVVILTLDGHISMLNAAALRFLDYSSAEEVRGRLLCELASPLAEEIERIPKDTT 176
Cdd:COG3850 188 QELYAELEEEEeleAELELLALLDELLLLAALLLLLALLLALLLAALLAALLLLLLLQDALAESELLALNILAGLLELLL 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 177 ETIRLSDSMIYRCSRLSFVDRGFSHPFILVESLTSEVVKAEKKAYEKVIRMIAHEVNNTTAGITSTLDTVDGALECMEDT 256
Cdd:COG3850 268 ALLLLLLASALLLLELELLALLLELVELLALAAAEEALLLLVELAALLLLLLLQAIANASLLLIALASVVAALLELASIL 347
|
....*.
gi 495112460 257 EDLREV 262
Cdd:COG3850 348 ALQAAL 353
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
336-431 |
2.04e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 46.12 E-value: 2.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 336 FEQVLVNIIKNAAESigetGDIFIR--TSVSPTMLEIADTGAGISKEVETKLFSPFFsTKPNGQ------GIGLIFIREV 407
Cdd:cd16948 10 IGQIVSNALKYSKQG----GKIEIYseTNEQGVVLSIKDFGIGIPEEDLPRVFDKGF-TGENGRnfqestGMGLYLVKKL 84
|
90 100
....*....|....*....|....
gi 495112460 408 LIKHGCTFSLRTYPDKLTRFRIRF 431
Cdd:cd16948 85 CDKLGHKIDVESEVGEGTTFTITF 108
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
336-430 |
2.60e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 45.95 E-value: 2.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 336 FEQVLVNIIKNAaesIG--ETGDIFIRTSVSPTM-------LEIADTGAGISKEVETKLFSPF------FSTKPNGQGIG 400
Cdd:cd16922 1 LRQILLNLLGNA---IKftEEGEVTLRVSLEEEEedgvqlrFSVEDTGIGIPEEQQARLFEPFsqadssTTRKYGGTGLG 77
|
90 100 110
....*....|....*....|....*....|.
gi 495112460 401 LIFIREvLIK-HGCTFSLRTYPDKLTRFRIR 430
Cdd:cd16922 78 LAISKK-LVElMGGDISVESEPGQGSTFTFT 107
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
342-431 |
8.45e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 44.50 E-value: 8.45e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 342 NIIKNAAESIGETGDIFIRTSVSPT--MLEIADTGAGISKEVETKLFSPFF------STKPNGQGIGLIFIREVLIKHGC 413
Cdd:cd16952 7 NLVSNAVKYTPPSDTITVRWSQEESgaRLSVEDTGPGIPPEHIPRLTERFYrvdierCRNTGGTGLGLAIVKHVMSRHDA 86
|
90
....*....|....*...
gi 495112460 414 TFSLRTYPDKLTRFRIRF 431
Cdd:cd16952 87 RLLIASELGKGSRFTCLF 104
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
338-431 |
1.17e-05 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 47.32 E-value: 1.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 338 QVLV-NIIKNAAESIGETGDIFIRTSVSPTML--EIADTGAGISKEVETKLFSPfFSTKPNGQGIGLIFIREVLIKH--- 411
Cdd:COG2972 342 QPLVeNAIEHGIEPKEGGGTIRISIRKEGDRLviTVEDNGVGMPEEKLEKLLEE-LSSKGEGRGIGLRNVRERLKLYyge 420
|
90 100
....*....|....*....|
gi 495112460 412 GCTFSLRTYPDKLTRFRIRF 431
Cdd:COG2972 421 EYGLEIESEPGEGTTVTIRI 440
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
337-430 |
1.55e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 43.57 E-value: 1.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 337 EQVLVNIIKNAAESIGETGDIFIRTSVSPTMLEIADTGAGISKEVETKLFSPFFSTKPN------GQGIGLIFIREVLIK 410
Cdd:cd16939 2 ARALDNLLRNALRYAHRTVRIALLVSGGRLTLIVEDDGPGIPAAARERVFEPFVRLDPSrdratgGFGLGLAIVHRVALW 81
|
90 100
....*....|....*....|
gi 495112460 411 HGCTFSLRTYPDKLTRFRIR 430
Cdd:cd16939 82 HGGHVECDDSELGGACFRLT 101
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
66-431 |
1.93e-05 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 46.82 E-value: 1.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 66 ELLREQDFSSRLTPVGQKEADRIVLVFNRMMEQLKDERLRLREQNHFLDLLVSASPMGVVILTLDGHISMLNAAALRFLD 145
Cdd:COG3920 122 VALLAALALLALLLLLLLLLAILALAELAVALAELAAALLLLAEELAALRLAAAALLLLLAALLDLGLALAALAAAALLA 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 146 YSSAEEVRGRLLCELASPLAEEIERIPKDTTETIRLSDSMIYRC------------SRLSFVDRGFSHPFILVESLTSEV 213
Cdd:COG3920 202 LLLALELLLALLLLLLLLLALLLVLLAALLRLRAAVLEELERRRrarglgrlllllLLLLLLLRALLLLAAGIRLVITER 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 214 VKAEKKAYEKV------IRMIAHEVNNTTAGITSTLD-TVDGAlecmeDTEDLREVMKVCIERCYSMSRFITNFAnvvki 286
Cdd:COG3920 282 KRAEEELEASLeekellLRELHHRVKNNLQVVSSLLRlQARRA-----DDPEAREALEESQNRIQALALVHELLY----- 351
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 287 PEPQLQSVDLNDRVAACKTFMETVCRNRKITLHLDLckenPEVMMDTS--------LFEqVLVNIIKNAAESiGETGDIF 358
Cdd:COG3920 352 QSEDWEGVDLRDYLRELLEPLRDSYGGRGIRIELDG----PDVELPADaavplgliLNE-LVTNALKHAFLS-GEGGRIR 425
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 495112460 359 IRTSVSPTM--LEIADTGAGISKEVEtklfspffstKPNGQGIGLIFIREVLIKHGCTFSLRtyPDKLTRFRIRF 431
Cdd:COG3920 426 VSWRREDGRlrLTVSDNGVGLPEDVD----------PPARKGLGLRLIRALVRQLGGTLELD--RPEGTRVRITF 488
|
|
| PAS |
COG2202 |
PAS domain [Signal transduction mechanisms]; |
102-170 |
2.16e-05 |
|
PAS domain [Signal transduction mechanisms];
Pssm-ID: 441804 [Multi-domain] Cd Length: 258 Bit Score: 45.79 E-value: 2.16e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 495112460 102 ERLRLREQNHFLDLLVSASPMGVVILTLDGHISMLNAAALRFLDYsSAEEVRGRLLCELASPLAEEIER 170
Cdd:COG2202 2 AEEALEESERRLRALVESSPDAIIITDLDGRILYVNPAFERLTGY-SAEELLGKTLRDLLPPEDDDEFL 69
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
338-430 |
2.86e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 42.94 E-value: 2.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 338 QVLVNIIKNAAE-SIGETGDIFIRTSVSPTMLEIA--DTGAGISKEVETKLFSPFFSTKPNGQ------GIGLIFIREVL 408
Cdd:cd16953 3 QVLRNLIGNAISfSPPDTGRITVSAMPTGKMVTISveDEGPGIPQEKLESIFDRFYTERPANEafgqhsGLGLSISRQII 82
|
90 100
....*....|....*....|....*.
gi 495112460 409 IKHG--CTFSLRTYPDKLT--RFRIR 430
Cdd:cd16953 83 EAHGgiSVAENHNQPGQVIgaRFTVQ 108
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
338-419 |
2.94e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 42.82 E-value: 2.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 338 QVLVNIIKNAAESIGetGDIFIRTSVSP--TMLEIADTGAGISKEVETKLFSPFF----STKPNGQGIGLIFIREVLIKH 411
Cdd:cd16950 3 RVLSNLVDNALRYGG--GWVEVSSDGEGnrTRIQVLDNGPGIAPEEVDELFQPFYrgdnARGTSGTGLGLAIVQRISDAH 80
|
....*...
gi 495112460 412 GCTFSLRT 419
Cdd:cd16950 81 GGSLTLAN 88
|
|
| PAS |
COG2202 |
PAS domain [Signal transduction mechanisms]; |
105-207 |
2.96e-05 |
|
PAS domain [Signal transduction mechanisms];
Pssm-ID: 441804 [Multi-domain] Cd Length: 258 Bit Score: 45.40 E-value: 2.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 105 RLREQNHFLDLLVSASPMGVVILTLDGHISMLNAAALRFLDYSSAEEVRGRLLCELASPLAEEIERIPKDTTETIRLSDS 184
Cdd:COG2202 131 ALRESEERLRLLVENAPDGIFVLDLDGRILYVNPAAEELLGYSPEELLGKSLLDLLHPEDRERLLELLRRLLEGGRESYE 210
|
90 100
....*....|....*....|...
gi 495112460 185 MIYRCSRLSFVDRGFSHPFILVE 207
Cdd:COG2202 211 LELRLKDGDGRWVWVEASAVPLR 233
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
15-263 |
1.23e-04 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 44.33 E-value: 1.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 15 TAVWTILLVLTLKERGALFYIGEGVITFSLVFLVYFYRKVVKPLDIIGNGMELLREQDFSSRLTPVGQKEADRIVLVFNR 94
Cdd:COG2770 197 GLLLVVLLEAALAALLLLLLLALLALLLALLLALLLARRITRPLRRLAEAARRIAAGDLDVRIPVSRKDEIGELARAFNR 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 95 MMEQLKD--ERLRLREQNHFLDLLVSASPMGVVILTLDGHISMLNAAALRFLDYSSAEEVRGRLLCELASPLAEEIERIP 172
Cdd:COG2770 277 MADSLREsiEEAEEEEELAEAELARLLEALLELLLALLLLLLALLLLAAAALLLELLLLLLLALLLLLLLAADLLLALAL 356
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 173 KDTTETIRLSDSMIYRCSRLSFVDRGFSHPFILVESLTSEVVKAEKKAYEKVIRMIAHEVNNTTAGITSTLDTVDGALEC 252
Cdd:COG2770 357 AALLLLLALELLLEAELLVLLALEALALEAELAAVLALLAALAAALLLLELALEELVLALLALALLALAAAAAAAEAAAA 436
|
250
....*....|.
gi 495112460 253 MEDTEDLREVM 263
Cdd:COG2770 437 ALELAAAAIAA 447
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
332-417 |
2.45e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 40.14 E-value: 2.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 332 DTSLFEQVLVNIIKNAAESIGETGDIFIRTSVSPTML--EIADTGAGISKEVETKLFSPFF----STKPNGQ-GIGLIFI 404
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGTVSISIYDEEEYLyfEIWDNGHGFSEQDLKKALELFYrddtSRRSGGHyGMGLYIA 80
|
90
....*....|...
gi 495112460 405 REVLIKHGCTFSL 417
Cdd:cd16975 81 KNLVEKHGGSLII 93
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
16-101 |
2.72e-04 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 43.09 E-value: 2.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 16 AVWTILLVLTLKERGALFYIGEGVITFSLVFLVYFYRKVVKPLDIIGNGMELLREQDFSSRLTPVGQKEADRIVLVFNRM 95
Cdd:COG0840 168 EAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKDEIGQLADAFNRM 247
|
....*.
gi 495112460 96 MEQLKD 101
Cdd:COG0840 248 IENLRE 253
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
288-430 |
2.79e-04 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 43.05 E-value: 2.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 288 EPQLQSVDL----NDRVAACKTFmetvcrNRKITLHLDLCKENPEVMMDTSLFEQVLVNIIKNAAESIGETGDIFIRTSV 363
Cdd:PRK10604 274 ELHLSEPDLpawlSTHLADIQAV------TPEKTVRLDTPHQGDYGALDMRLMERVLDNLLNNALRYAHSRVRVSLLLDG 347
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 495112460 364 SPTMLEIADTGAGISKEVETKLFSPFFSTKPN------GQGIGLIFIREVLIKHGCTFSLRTYPDKLTRFRIR 430
Cdd:PRK10604 348 NQACLIVEDDGPGIPPEERERVFEPFVRLDPSrdratgGCGLGLAIVHSIALAMGGSVNCDESELGGARFSFS 420
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
52-101 |
3.44e-04 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 38.38 E-value: 3.44e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 495112460 52 RKVVKPLDIIGNGMELLREQDFSSRLTPVGQKEADRIVLVFNRMMEQLKD 101
Cdd:smart00304 1 RRLLRPLRRLAEAAQRIADGDLTVRLPVDGRDEIGELARAFNEMADRLEE 50
|
|
| RocR |
COG3829 |
RocR-type transcriptional regulator, contains PAS, AAA-type ATPase, and DNA-binding Fis ... |
102-170 |
3.84e-04 |
|
RocR-type transcriptional regulator, contains PAS, AAA-type ATPase, and DNA-binding Fis domains [Transcription, Signal transduction mechanisms];
Pssm-ID: 443041 [Multi-domain] Cd Length: 448 Bit Score: 42.45 E-value: 3.84e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 495112460 102 ERLRLREQNHFLDLLVSASPMGVVILTLDGHISMLNAAALRFLDYsSAEEVRGRLLCEL--ASPLAEEIER 170
Cdd:COG3829 2 EELELKELEEELEAILDSLDDGIIVVDADGRITYVNRAAERILGL-PREEVIGKNVTELipNSPLLEVLKT 71
|
|
| HAMP |
pfam00672 |
HAMP domain; |
50-101 |
4.18e-04 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 37.99 E-value: 4.18e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 495112460 50 FYRKVVKPLDIIGNGMELLREQDFSSRLTPVGQKEADRIVLVFNRMMEQLKD 101
Cdd:pfam00672 2 LARRILRPLRRLAEAARRIASGDLDVRLPVSGRDEIGELARAFNQMAERLRE 53
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
18-109 |
4.84e-04 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 42.31 E-value: 4.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 18 WTILLVLTLKE--------RGALFYIGEGVITFSLVFLVYFYRKVVKPLDIIGNGMELLREQDFSsRLTPVGQKEADRIV 89
Cdd:COG2972 137 WTLVSLIPKSElfrglfslRRLILLIILLLLLLALLLSYLLSRSITRPIKRLKKAMKKVEKGDLV-RLEVSGNDEIGILA 215
|
90 100
....*....|....*....|
gi 495112460 90 LVFNRMMEQLKDERLRLREQ 109
Cdd:COG2972 216 RSFNEMVERIKELIEEVYEL 235
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
337-409 |
7.66e-04 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 41.88 E-value: 7.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 337 EQVLVNIIKNAAEsIGETGDIFIRTSVSPTMLEIA--DTGAGIS-KEVeTKLFSPFFSTKPNGQ------GIGLIfIREV 407
Cdd:PRK10841 564 QQVISNLLSNAIK-FTDTGCIVLHVRVDGDYLSFRvrDTGVGIPaKEV-VRLFDPFFQVGTGVQrnfqgtGLGLA-ICEK 640
|
..
gi 495112460 408 LI 409
Cdd:PRK10841 641 LI 642
|
|
| HATPase_CheA-like |
cd16916 |
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some ... |
313-430 |
1.50e-03 |
|
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some hybrid sensor histidine kinases; This family includes the cytoplasmic histidine kinase (HK) CheA, a transmembrane receptor which, together with cytoplasmic adaptor protein (CheW), forms the lattice at the core of the chemosensory array that controls the cellular chemotaxis of motile bacteria and archaea. CheA forms a two-component signal transduction system (TCS) with the response regulator CheY. Proteins having this CheA-like HATPase domain generally also have a histidine-phosphotransfer domain, a histidine kinase homodimeric domain, and a regulatory domain; some are hybrid sensor histidine kinases as they contain a REC signal receiver domain.
Pssm-ID: 340393 [Multi-domain] Cd Length: 178 Bit Score: 39.49 E-value: 1.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 313 NRKITLHLdlckENPEVMMDTSLFEQV---LVNIIKNAA----ESIGE--------TGDIFIRTSVSPTML--EIADTGA 375
Cdd:cd16916 17 GKQVELVV----EGEDTELDKSVLEKLadpLTHLLRNAVdhgiEAPEErlaagkppEGTITLRAEHQGNQVviEVSDDGR 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 376 GISK------------------------EVETKLFSPFFSTKP-----NGQGIGLIFIREVLIKHGCTFSLRTYPDKLTR 426
Cdd:cd16916 93 GIDRekirekaierglitadeaatlsddEVLNLIFAPGFSTAEqvtdvSGRGVGMDVVKRSIESLGGTIEVESEPGQGTT 172
|
....
gi 495112460 427 FRIR 430
Cdd:cd16916 173 FTIR 176
|
|
| PRK13560 |
PRK13560 |
hypothetical protein; Provisional |
100-161 |
2.32e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 106506 [Multi-domain] Cd Length: 807 Bit Score: 40.43 E-value: 2.32e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 495112460 100 KDERLRLREQNHFLDLLVSASPMGVVILTLDGHISMLNAAALRFLDYSSaEEVRGRLLCELA 161
Cdd:PRK13560 193 KRAEERIDEALHFLQQLLDNIADPAFWKDEDAKVFGCNDAACLACGFRR-EEIIGMSIHDFA 253
|
|
| PAS_8 |
pfam13188 |
PAS domain; PAS domains are involved in many signalling proteins where they are used as a ... |
112-171 |
2.65e-03 |
|
PAS domain; PAS domains are involved in many signalling proteins where they are used as a signal sensor domain. PAS domains appear in archaea, bacteria and eukaryotes. Several PAS-domain proteins are known to detect their signal by way of an associated cofactor. Heme, flavin, and a 4-hydroxycinnamyl chromophore are used in different proteins. This domain recognizes oxygen and CO (Matilla et al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 463802 [Multi-domain] Cd Length: 65 Bit Score: 36.37 E-value: 2.65e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 112 FLDLLVSASPMGVVILTLDGHISMLNAAALRFLDYSSAEEVRGRLLCELASPLAEEIERI 171
Cdd:pfam13188 2 RLRALFESSPDGILVLDEGGRIIYVNPAALELLGYELLGELLGELLDLLDPLLEDALELL 61
|
|
| PAS |
cd00130 |
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
120-163 |
5.06e-03 |
|
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in signal transduction.
Pssm-ID: 238075 [Multi-domain] Cd Length: 103 Bit Score: 36.46 E-value: 5.06e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 495112460 120 SPMGVVILTLDGHISMLNAAALRFLDYsSAEEVRGRLLCELASP 163
Cdd:cd00130 1 LPDGVIVLDLDGRILYANPAAEQLLGY-SPEELIGKSLLDLIHP 43
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
336-430 |
5.29e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 36.21 E-value: 5.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 336 FEQVLVNIIKNAAESIGETGDIFIRTSVspTMLEIADTGAGISKEVETKLFSPFF----STKPNGQGIGLIFIREVLIKH 411
Cdd:cd16923 5 FSNLLSNAIKYSPENTRIYITSFLTDDV--VNIMFKNPSSHPLDFKLEKLFERFYrgdnSRNTEGAGLGLSIAKAIIELH 82
|
90
....*....|....*....
gi 495112460 412 GCTFSLRtYPDKLTRFRIR 430
Cdd:cd16923 83 GGSASAE-YDDNHDLFKVR 100
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
319-429 |
7.08e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 36.34 E-value: 7.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 319 HLDLCKENPEVMMDTSLFEQVLVNIIKNAAE--SIGETGDIFIRTSVSPTMLEIADTGAGISKEVETKLFSPFFSTKPN- 395
Cdd:cd16947 4 EINIPDRPIYANANTEALQRILKNLISNAIKygSDGKFLGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYTLEDSr 83
|
90 100 110
....*....|....*....|....*....|....*....
gi 495112460 396 -----GQGIGLIFIREVLIKHGCTFSLRTYPDKLTRFRI 429
Cdd:cd16947 84 nsakqGNGLGLTITKRLAESMGGSIYVNSKPYEKTVFTV 122
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
331-429 |
7.59e-03 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 38.66 E-value: 7.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 331 MDTSLFEQVLVNIIKNAAESI------GETGDIFIRTSVSPTMLEIADTGAGISKEVETKLFSPFFSTK---PNGQGIGL 401
Cdd:PRK15053 428 LDSTEFAAIVGNLLDNAFEASlrsdegNKIVELFLSDEGDDVVIEVADQGCGVPESLRDKIFEQGVSTRadePGEHGIGL 507
|
90 100
....*....|....*....|....*...
gi 495112460 402 IFIREVLIKHGCTFSLRTYPDKLTRFRI 429
Cdd:PRK15053 508 YLIASYVTRCGGVITLEDNDPCGTLFSI 535
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
288-431 |
7.90e-03 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 38.35 E-value: 7.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495112460 288 EPQLQSVDLNDRVAacktfmETVC--RNRKITLHLDLCKENPEVMMDTSLFEQVLVNIIKNAAEsIGeTGDIFIRTSVSP 365
Cdd:PRK09467 288 EMPMEMADLNALLG------EVIAaeSGYEREIETALQPGPIEVPMNPIAIKRALANLVVNAAR-YG-NGWIKVSSGTEG 359
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 495112460 366 TM--LEIADTGAGISKEVETKLFSPFfsTKPN------GQGIGLIFIREVLIKHGCTFSLRTYPDKLTRFRIRF 431
Cdd:PRK09467 360 KRawFQVEDDGPGIPPEQLKHLFQPF--TRGDsargssGTGLGLAIVKRIVDQHNGKVELGNSEEGGLSARAWL 431
|
|
| |
