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Conserved domains on  [gi|493417299|ref|WP_006373171|]
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MULTISPECIES: PadR family transcriptional regulator [Gordonia]

Protein Classification

PadR family transcriptional regulator( domain architecture ID 11447737)

PadR family transcriptional regulator similar to the phenolic acid decarboxylation repressor, which is a transcription factor that represses genes associated with the phenolic acid stress response in gram-positive bacteria

Gene Ontology:  GO:0003677|GO:0003700
PubMed:  10679470|10908318|10473770|15808743|8831795

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
1-86 2.96e-27

DNA-binding transcriptional regulator, PadR family [Transcription];


:

Pssm-ID: 441301  Cd Length: 102  Bit Score: 100.40  E-value: 2.96e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493417299   1 MLEMAILGLLLESPMHGYELRKRLTGLLGAFRAFSYGSLYPTLRRMQADGLIDETSAPSGvkVRRGRRVYQLTDAGRERF 80
Cdd:COG1695    9 TLELLILALLAEGPMYGYEIIKELEERSGGFWKVSEGTLYPALKRLEKEGLVESEWEESE--GGPRRKYYRLTEAGREEL 86


                 ....*.
gi 493417299  81 TELVAD 86
Cdd:COG1695   87 AEWLEE 92
 
Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
1-86 2.96e-27

DNA-binding transcriptional regulator, PadR family [Transcription];


Pssm-ID: 441301  Cd Length: 102  Bit Score: 100.40  E-value: 2.96e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493417299   1 MLEMAILGLLLESPMHGYELRKRLTGLLGAFRAFSYGSLYPTLRRMQADGLIDETSAPSGvkVRRGRRVYQLTDAGRERF 80
Cdd:COG1695    9 TLELLILALLAEGPMYGYEIIKELEERSGGFWKVSEGTLYPALKRLEKEGLVESEWEESE--GGPRRKYYRLTEAGREEL 86


                 ....*.
gi 493417299  81 TELVAD 86
Cdd:COG1695   87 AEWLEE 92
PadR pfam03551
Transcriptional regulator PadR-like family; Members of this family are transcriptional ...
 6-81 4.70e-22

Transcriptional regulator PadR-like family; Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.


Pssm-ID: 397561  Cd Length: 74  Bit Score: 86.15  E-value: 4.70e-22
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 493417299    6 ILGLLLESPMHGYELRKRLTGLLGAFRAFSYGSLYPTLRRMQADGLIDETSAPSGvkVRRGRRVYQLTDAGRERFT 81
Cdd:pfam03551   1 VLAVLGEQPRYGYEIIKELEELSGGFWRPSEGTLYPILKRLEKEGLVESEWVDSG--GGPPRKYYRLTDAGRRELA 74
PRK05638 PRK05638
threonine synthase; Validated
 6-82 3.26e-05

threonine synthase; Validated


Pssm-ID: 235539 [Multi-domain]  Cd Length: 442  Bit Score: 44.42  E-value: 3.26e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 493417299   6 ILGLLLESPMHGYELRKRLTgllgafRAFSYGSLYPTLRRMQADGLIDEtsapsgvKVRRGRRVY-QLTDAGReRFTE 82
Cdd:PRK05638 376 ILKILSEREMYGYEIWKALG------KPLKYQAVYQHIKELEELGLIEE-------AYRKGRRVYyKLTEKGR-RLLE 439
 
Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
1-86 2.96e-27

DNA-binding transcriptional regulator, PadR family [Transcription];


Pssm-ID: 441301  Cd Length: 102  Bit Score: 100.40  E-value: 2.96e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493417299   1 MLEMAILGLLLESPMHGYELRKRLTGLLGAFRAFSYGSLYPTLRRMQADGLIDETSAPSGvkVRRGRRVYQLTDAGRERF 80
Cdd:COG1695    9 TLELLILALLAEGPMYGYEIIKELEERSGGFWKVSEGTLYPALKRLEKEGLVESEWEESE--GGPRRKYYRLTEAGREEL 86


                 ....*.
gi 493417299  81 TELVAD 86
Cdd:COG1695   87 AEWLEE 92
PadR pfam03551
Transcriptional regulator PadR-like family; Members of this family are transcriptional ...
 6-81 4.70e-22

Transcriptional regulator PadR-like family; Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.


Pssm-ID: 397561  Cd Length: 74  Bit Score: 86.15  E-value: 4.70e-22
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 493417299    6 ILGLLLESPMHGYELRKRLTGLLGAFRAFSYGSLYPTLRRMQADGLIDETSAPSGvkVRRGRRVYQLTDAGRERFT 81
Cdd:pfam03551   1 VLAVLGEQPRYGYEIIKELEELSGGFWRPSEGTLYPILKRLEKEGLVESEWVDSG--GGPPRKYYRLTDAGRRELA 74
PRK05638 PRK05638
threonine synthase; Validated
 6-82 3.26e-05

threonine synthase; Validated


Pssm-ID: 235539 [Multi-domain]  Cd Length: 442  Bit Score: 44.42  E-value: 3.26e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 493417299   6 ILGLLLESPMHGYELRKRLTgllgafRAFSYGSLYPTLRRMQADGLIDEtsapsgvKVRRGRRVY-QLTDAGReRFTE 82
Cdd:PRK05638 376 ILKILSEREMYGYEIWKALG------KPLKYQAVYQHIKELEELGLIEE-------AYRKGRRVYyKLTEKGR-RLLE 439
COG2345 COG2345
Predicted transcriptional regulator, ArsR family [Transcription];
43-80 7.40e-03

Predicted transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 441914 [Multi-domain]  Cd Length: 217  Bit Score: 36.44  E-value: 7.40e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 493417299  43 LRRMQADGLIDETSAPSGvkvrRGR--RVYQLTDAGRERF 80
Cdd:COG2345   48 LDALEEEGLVERETERRG----RGRpaKLYRLTEAGRARF 83
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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