|
Name |
Accession |
Description |
Interval |
E-value |
| OMP_RagA_SusC |
TIGR04056 |
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ... |
21-981 |
0e+00 |
|
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 274948 [Multi-domain] Cd Length: 981 Bit Score: 731.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 21 QKVTGKVKDSSGEPVIGASVVVKGNnTMGTITDFDGNFMLDVPAKSVLVISYIGYVTQEVPTAGKNSLEIVLKEDTKTLD 100
Cdd:TIGR04056 1 ITVTGVVVDETGEPLIGASVVVKGT-TNGTITDIDGNFSLKVPPGAVLVFSYIGYKTQEVKVKGQKNLNITLKEDTQELD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 101 EVVVIGYGTQRKGDVTSSVASVKADNFVKGAVKDVGQLIQGKVAGLAITNPNGDPTGSTQIRLRGTNTIGGaNTAPLVLI 180
Cdd:TIGR04056 80 EVVVVGYGTQKKKSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSGEPGGDAEIWIRGISSFGG-NNSPLYVI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 181 DGIPGE--LGTVAPEDVESVDVLKDGSAAAIYGTRGTNGVILITTKQAKgVDINQVEYNGYVSTSLIAKKLDMLNADEFR 258
Cdd:TIGR04056 159 DGVPRDngLSDLNPEDIESISVLKDASATAIYGSRGANGVILITTKRGK-EGKPKISYNAEFGFSTPTRLPEMLNAYEYA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 259 TLY--------------------------PDQDHGADTDWIDEI-SRTPVSHVHNLSLMGGNSKTNYIANLNYASRQGIM 311
Cdd:TIGR04056 238 ELYneallnrgssppdiytdeeieayrngLDPDLYPNTDWQDEIfKRTAFNQRHNLSVSGGTEKARYYVSLGYYNEEGIL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 312 KKSDFESFQGRIEVTHRmFDDKLKLKFGL---FGKKNQMESTTSgGSFRGwVYGQATRRNPTDPVRNEDGTWNENVSKFE 388
Cdd:TIGR04056 318 KNSDYKRYNFRANIDAK-LTKTLKLSLNVsgsLSKYNNPGGSTS-NIWGA-LMLFPRGTPYSTPPVYSDGYYPAYNSGNT 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 389 YE-NPLALLYEAEGNVKKTQLRYNGNIVYNPIKDLTLSAVFSYIRDNmnrGYGETLNHISaLRDGLAGWSSVGAYTKMEK 467
Cdd:TIGR04056 395 SLqNPYALLNRGYNENERNRLNGNASLEQKITKGLKLKGTFSYDYSN---YKNKKYYKNP-YYYNATGGANNGYYSESNS 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 468 -----LMELTAQYNKEIGAHKFSVLGGYSYNETDFeelwiDNYGFQddyFGGWHNIGIGSAlkdgKANIGSKKTPTNLIG 542
Cdd:TIGR04056 471 rsrnyYLEATLNYNRTFGKHNVSALLGYSQQENKS-----SSYGGL---LDDLPSLDAGTS----DASVSGSDSEYRLQS 538
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 543 FFGRATYSFKNRYLLMGALRYEGASQLwGTDNAWGLFPSISVGWRITEEAFMKN-QKIFDDLKLRVGYGVTGSQ-PKDPF 620
Cdd:TIGR04056 539 LFGRATYSYKDRYLLEFNFRYDGSSRF-AKGNRWGFFPSVSLGWRISEEKFMKKlKKWLSFLKLRASYGIVGNDnIGDRY 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 621 LGVAMLKYG----SYAFVNGNWVQTIVPASNPNPDLKWEEKKETNIGLDFVSWGGRLSGSIDYYNRDVDGLIYEygVPTP 696
Cdd:TIGR04056 618 PYLSLYNLGdggyNFGTNNGTSVTGITESRYGNPNLKWEKTKKWNLGLDLGFFNNRLSLTVDYYYKKTKDILQS--RSLP 695
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 697 PNL-YNKTMANGGTMRNRGVEVLVTVVPVQNKDFEWSTTGTFSLNSNKLISLSGSIFK-SDYDYfntgtveysgqvadsh 774
Cdd:TIGR04056 696 SVTgYSSPYANIGKVKNKGVELSLNYRNKIGKDFSWSVRGNFTYNKNKILELDEGAYLpVKYPY---------------- 759
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 775 RVQVGESIGNFYGFKVV----DVDSE---------GRWIYEDRNGelvnykDFTHAPEDKHVIGN-GLPKWYAGWNNTLR 840
Cdd:TIGR04056 760 ISKEGGPIGQIYGYIADglfkDDDSPkqtfgnvrpGDIKYKDVNG------DGKIDDDDRVPIGYsNTPDLTYGFGNSFS 833
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 841 YKNFDLNVTMRGAFGFQIINGGRMNYENVKNSRFENRLKSVNDLVFGKHT------LSPEVEPEFN-----SYYVEDGDY 909
Cdd:TIGR04056 834 YKGFDLSALFQGSGGGDVFNDGRGFYPFNGGDWGNVLKIVADNRWTPENPnadyprLSYGDSNNSNnyqasTRWLEDGSY 913
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492458075 910 WKIDNITLGYSFGQ--VGK-YIKSLRIYGSVLNALTITGYKGIDPEVstdgltPGYDTRdRYPSVRSFTFGVNVK 981
Cdd:TIGR04056 914 LRLKNLTLGYTLPKkwLKKiGISNLRVYFSGQNLFTFSKYKGWDPEL------QGNDGG-AYPLQRTFSFGVNLT 981
|
|
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
99-769 |
5.22e-52 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 193.89 E-value: 5.22e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 99 LDEVVVIGYGT-QRKGDVTSSVASVKADNFVKGAVKDVGQLIQgKVAGLAITNPNGdptGSTQIRLRGtntIGGANTAPL 177
Cdd:COG1629 1 LEEVVVTATRTdESLQDVPGSVSVISREQLEDQPATDLGDLLR-RVPGVSVTSAGG---GAGQISIRG---FGGGGNRVL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 178 VLIDGIP--------GELGTVAPEDVESVDVLKdGSAAAIYGTRGTNGVILITTKQAKGvdinqvEYNGYVSTSLIakkl 249
Cdd:COG1629 74 VLVDGVPlndpsggdGGLSYIDPEDIERVEVLR-GPSSALYGSGALGGVINIVTKKPKD------GKGGEVSASYG---- 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 250 dmlNADEFRtlypdqdhgadtdwideisrtpvshvHNLSLMGGNSKTNYIANLNYASRQGIMKKSDFESFQGRIEVTHRm 329
Cdd:COG1629 143 ---SYGTYR--------------------------ASLSLSGGNGKLAYRLSASYRDSDGYRDNSDSDRYNLRAKLGYQ- 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 330 FDDKLKLKFGLFGkkNQMESTTSGGSFRGWVYGQATRRNPTDPVRNedgtwnenvskfeyenplallyeaeGNVKKTQLR 409
Cdd:COG1629 193 LGDDTRLTLSASY--SDSDQDSPGYLTLAALRPRGAMDDGTNPYSN-------------------------DTDDNTRDR 245
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 410 YNGNIVYNPIKD-LTLSAVFSYirdnmnRGYGETLNHISALRDGLAGWSSVGAYTKMEKLMELTAQYNKEIGAhKFSVLG 488
Cdd:COG1629 246 YSLSLEYEHLGDgLKLSASAYY------RYDDTDLDSDFTPTPADGGTLEQTDFDNRTYGLELRLTYDLGFGG-KHTLLV 318
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 489 GYSYnetdfeelwidnygFQDDYFGGWHNIGIGSALKDGKANIGSKKTPTNLIGFFGRATYSFKNRYLLMGALRYE---- 564
Cdd:COG1629 319 GLDY--------------QRQDLDGSGYPLDLGSGSLPTLTSGADDDGTTTSLALYAQDTYKLTDKLTLTAGLRYDyvsy 384
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 565 -------GASQLWGTDNAWGLFPSISVGWRITeeafmknqkifDDLKLRVGYGvTGSQPkdpflgvamlkyGSYAFVNGN 637
Cdd:COG1629 385 dvddtvtGTDSASGSRSYSAFSPSLGLTYQLS-----------PNLSLYASYS-RGFRA------------PTFGELYAN 440
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 638 wvqTIVPASNPNPDLKWEEKKETNIGLDFVSWGGRLSGSIDYYNRDVDGLIYEYGVPTPPNLYNkTMANGGTMRNRGvev 717
Cdd:COG1629 441 ---GTDPYSVGNPDLKPETSTNYELGLRYRLLDGRLSLSLALFYSDVDNEILSVPLPNDSGFST-YYTNAGKARSYG--- 513
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|..
gi 492458075 718 lvtvvpvqnkdFEWSTTGTFSLNSNklISLSGSIFKSDYDYFNTGTVEYSGQ 769
Cdd:COG1629 514 -----------VELELSYQLTPGLS--LNASYSYTDAKFDDDTDGSADLDGN 552
|
|
| CarbopepD_reg_2 |
pfam13715 |
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ... |
23-104 |
2.24e-19 |
|
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.
Pssm-ID: 433425 [Multi-domain] Cd Length: 88 Bit Score: 83.41 E-value: 2.24e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 23 VTGKVKD-SSGEPVIGASVVVKGNNTmGTITDFDGNFML-DVPAKSV-LVISYIGYVTQEVP-TAGKNS---LEIVLKED 95
Cdd:pfam13715 1 ISGTVVDeNTGEPLPGATVYVKGTTK-GTVTDADGNFELkNLPAGTYtLVVSFVGYKTQEKKvTVSNDNtldVNFLLKED 79
|
....*....
gi 492458075 96 TKTLDEVVV 104
Cdd:pfam13715 80 ALLLDEVVV 88
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
118-714 |
1.14e-14 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 78.26 E-value: 1.14e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 118 SVASVKADNFVKGAVKDVGQLIQgKVAGLAITNPNGDptGSTQIRLRGTntiGGANTapLVLIDGIP---------GELG 188
Cdd:cd01347 1 SVSVITAEDIEKQPATSLADLLR-RIPGVSVTRGGGG--GGSTISIRGF---GPDRT--LVLVDGLPlassnygrgVDLN 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 189 TVAPEDVESVDVLKdGSAAAIYGTRGTNGVILITTKQAKGVDINQVEYnGYvstsliakkldmlNADEFRTLYPDQ-DHG 267
Cdd:cd01347 73 TIPPELIERVEVLK-GPSSALYGSGAIGGVVNIITKRPTDEFGGSVTA-GY-------------GSDNSGSSGGGGfDVS 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 268 ADTDWIDEIS-RTPVSHVHNLSLMGGNSKTNYIANlnyaSRQGIMKKSDFEsfqgrievthrmFDDKLKLKFGLFGKKNQ 346
Cdd:cd01347 138 GALADDGAFGaRLYGAYRDGDGTIDGDGQADDSDE----ERYNVAGKLDWR------------PDDDTRLTLDAGYQDQD 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 347 MESTTSGGSFRGwvyGQATRRNPTDPVRNEDGTWNENVSkfeYENPLALLYEAEGNvkktqlryngnivynpIKDLTLSA 426
Cdd:cd01347 202 ADGPGGTLPANG---TGSSLGGGPSSNTNGDRDWDYRDR---YRKRASLGLEHDLN----------------DTGWTLRA 259
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 427 VFSYIRDNMNRgygETLNHISALRDGLAGWSSVGAYTKMEKLME-LTAQYNKEIGAH--KFSVLGGYSYNETDFEElwid 503
Cdd:cd01347 260 NLSYSYTDNDG---DPLILNGGNNAAGGDLGRSGYSSERDTTQLgFDAGLNAPFGTGpvAHTLTLGVEYRREELDE---- 332
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 504 nygfqddyfggwhnigigsalkdgkanigskktptNLIGFFGRATYSFKNRYLLMGALRYE-----------GASQLWGT 572
Cdd:cd01347 333 -----------------------------------KQTALYAQDTIELTDDLTLTLGLRYDhydqdskdtiaGGTTAKKS 377
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 573 DNAWGlfPSISVGWRITeeafmknqkifDDLKLRVGYGvTGSQPKDPflgvamlkYGSYAFVNgnwvqTIVPASNPNPDL 652
Cdd:cd01347 378 YSHWS--PSLGLVYKLT-----------DGLSLYASYS-QGFRAPSL--------GELYGGGS-----HGGTAAVGNPNL 430
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492458075 653 KWEEKKETNIGLDFvSWGGRLSGSIDYYNRDVDGLIYEYGVPTPPNLYNkTMANGGTMRNRG 714
Cdd:cd01347 431 KPEKSKQYELGLKY-DPGDGLTLSAALFRIDIKNEIVSTPTNTGLGLVT-VYVNGGKARIRG 490
|
|
| PRK13528 |
PRK13528 |
outer membrane receptor FepA; Provisional |
132-225 |
1.63e-05 |
|
outer membrane receptor FepA; Provisional
Pssm-ID: 237413 [Multi-domain] Cd Length: 727 Bit Score: 48.98 E-value: 1.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 132 VKDVGQLIQgKVAGLAIT--NPNGDPTGSTQIRLRGtntIGGANTapLVLIDGIP------------GELGT------VA 191
Cdd:PRK13528 67 VNDLSDIIR-KMPGVNLTgnSASGTRGNNRQIDIRG---MGPENT--LILIDGVPvtsrnsvryswrGERDTrgdtnwVP 140
|
90 100 110
....*....|....*....|....*....|....
gi 492458075 192 PEDVESVDVLKdGSAAAIYGTRGTNGVILITTKQ 225
Cdd:PRK13528 141 PEMVERIEVIR-GPAAARYGSGAAGGVVNIITKR 173
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| OMP_RagA_SusC |
TIGR04056 |
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ... |
21-981 |
0e+00 |
|
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 274948 [Multi-domain] Cd Length: 981 Bit Score: 731.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 21 QKVTGKVKDSSGEPVIGASVVVKGNnTMGTITDFDGNFMLDVPAKSVLVISYIGYVTQEVPTAGKNSLEIVLKEDTKTLD 100
Cdd:TIGR04056 1 ITVTGVVVDETGEPLIGASVVVKGT-TNGTITDIDGNFSLKVPPGAVLVFSYIGYKTQEVKVKGQKNLNITLKEDTQELD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 101 EVVVIGYGTQRKGDVTSSVASVKADNFVKGAVKDVGQLIQGKVAGLAITNPNGDPTGSTQIRLRGTNTIGGaNTAPLVLI 180
Cdd:TIGR04056 80 EVVVVGYGTQKKKSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSGEPGGDAEIWIRGISSFGG-NNSPLYVI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 181 DGIPGE--LGTVAPEDVESVDVLKDGSAAAIYGTRGTNGVILITTKQAKgVDINQVEYNGYVSTSLIAKKLDMLNADEFR 258
Cdd:TIGR04056 159 DGVPRDngLSDLNPEDIESISVLKDASATAIYGSRGANGVILITTKRGK-EGKPKISYNAEFGFSTPTRLPEMLNAYEYA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 259 TLY--------------------------PDQDHGADTDWIDEI-SRTPVSHVHNLSLMGGNSKTNYIANLNYASRQGIM 311
Cdd:TIGR04056 238 ELYneallnrgssppdiytdeeieayrngLDPDLYPNTDWQDEIfKRTAFNQRHNLSVSGGTEKARYYVSLGYYNEEGIL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 312 KKSDFESFQGRIEVTHRmFDDKLKLKFGL---FGKKNQMESTTSgGSFRGwVYGQATRRNPTDPVRNEDGTWNENVSKFE 388
Cdd:TIGR04056 318 KNSDYKRYNFRANIDAK-LTKTLKLSLNVsgsLSKYNNPGGSTS-NIWGA-LMLFPRGTPYSTPPVYSDGYYPAYNSGNT 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 389 YE-NPLALLYEAEGNVKKTQLRYNGNIVYNPIKDLTLSAVFSYIRDNmnrGYGETLNHISaLRDGLAGWSSVGAYTKMEK 467
Cdd:TIGR04056 395 SLqNPYALLNRGYNENERNRLNGNASLEQKITKGLKLKGTFSYDYSN---YKNKKYYKNP-YYYNATGGANNGYYSESNS 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 468 -----LMELTAQYNKEIGAHKFSVLGGYSYNETDFeelwiDNYGFQddyFGGWHNIGIGSAlkdgKANIGSKKTPTNLIG 542
Cdd:TIGR04056 471 rsrnyYLEATLNYNRTFGKHNVSALLGYSQQENKS-----SSYGGL---LDDLPSLDAGTS----DASVSGSDSEYRLQS 538
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 543 FFGRATYSFKNRYLLMGALRYEGASQLwGTDNAWGLFPSISVGWRITEEAFMKN-QKIFDDLKLRVGYGVTGSQ-PKDPF 620
Cdd:TIGR04056 539 LFGRATYSYKDRYLLEFNFRYDGSSRF-AKGNRWGFFPSVSLGWRISEEKFMKKlKKWLSFLKLRASYGIVGNDnIGDRY 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 621 LGVAMLKYG----SYAFVNGNWVQTIVPASNPNPDLKWEEKKETNIGLDFVSWGGRLSGSIDYYNRDVDGLIYEygVPTP 696
Cdd:TIGR04056 618 PYLSLYNLGdggyNFGTNNGTSVTGITESRYGNPNLKWEKTKKWNLGLDLGFFNNRLSLTVDYYYKKTKDILQS--RSLP 695
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 697 PNL-YNKTMANGGTMRNRGVEVLVTVVPVQNKDFEWSTTGTFSLNSNKLISLSGSIFK-SDYDYfntgtveysgqvadsh 774
Cdd:TIGR04056 696 SVTgYSSPYANIGKVKNKGVELSLNYRNKIGKDFSWSVRGNFTYNKNKILELDEGAYLpVKYPY---------------- 759
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 775 RVQVGESIGNFYGFKVV----DVDSE---------GRWIYEDRNGelvnykDFTHAPEDKHVIGN-GLPKWYAGWNNTLR 840
Cdd:TIGR04056 760 ISKEGGPIGQIYGYIADglfkDDDSPkqtfgnvrpGDIKYKDVNG------DGKIDDDDRVPIGYsNTPDLTYGFGNSFS 833
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 841 YKNFDLNVTMRGAFGFQIINGGRMNYENVKNSRFENRLKSVNDLVFGKHT------LSPEVEPEFN-----SYYVEDGDY 909
Cdd:TIGR04056 834 YKGFDLSALFQGSGGGDVFNDGRGFYPFNGGDWGNVLKIVADNRWTPENPnadyprLSYGDSNNSNnyqasTRWLEDGSY 913
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492458075 910 WKIDNITLGYSFGQ--VGK-YIKSLRIYGSVLNALTITGYKGIDPEVstdgltPGYDTRdRYPSVRSFTFGVNVK 981
Cdd:TIGR04056 914 LRLKNLTLGYTLPKkwLKKiGISNLRVYFSGQNLFTFSKYKGWDPEL------QGNDGG-AYPLQRTFSFGVNLT 981
|
|
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
99-769 |
5.22e-52 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 193.89 E-value: 5.22e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 99 LDEVVVIGYGT-QRKGDVTSSVASVKADNFVKGAVKDVGQLIQgKVAGLAITNPNGdptGSTQIRLRGtntIGGANTAPL 177
Cdd:COG1629 1 LEEVVVTATRTdESLQDVPGSVSVISREQLEDQPATDLGDLLR-RVPGVSVTSAGG---GAGQISIRG---FGGGGNRVL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 178 VLIDGIP--------GELGTVAPEDVESVDVLKdGSAAAIYGTRGTNGVILITTKQAKGvdinqvEYNGYVSTSLIakkl 249
Cdd:COG1629 74 VLVDGVPlndpsggdGGLSYIDPEDIERVEVLR-GPSSALYGSGALGGVINIVTKKPKD------GKGGEVSASYG---- 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 250 dmlNADEFRtlypdqdhgadtdwideisrtpvshvHNLSLMGGNSKTNYIANLNYASRQGIMKKSDFESFQGRIEVTHRm 329
Cdd:COG1629 143 ---SYGTYR--------------------------ASLSLSGGNGKLAYRLSASYRDSDGYRDNSDSDRYNLRAKLGYQ- 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 330 FDDKLKLKFGLFGkkNQMESTTSGGSFRGWVYGQATRRNPTDPVRNedgtwnenvskfeyenplallyeaeGNVKKTQLR 409
Cdd:COG1629 193 LGDDTRLTLSASY--SDSDQDSPGYLTLAALRPRGAMDDGTNPYSN-------------------------DTDDNTRDR 245
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 410 YNGNIVYNPIKD-LTLSAVFSYirdnmnRGYGETLNHISALRDGLAGWSSVGAYTKMEKLMELTAQYNKEIGAhKFSVLG 488
Cdd:COG1629 246 YSLSLEYEHLGDgLKLSASAYY------RYDDTDLDSDFTPTPADGGTLEQTDFDNRTYGLELRLTYDLGFGG-KHTLLV 318
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 489 GYSYnetdfeelwidnygFQDDYFGGWHNIGIGSALKDGKANIGSKKTPTNLIGFFGRATYSFKNRYLLMGALRYE---- 564
Cdd:COG1629 319 GLDY--------------QRQDLDGSGYPLDLGSGSLPTLTSGADDDGTTTSLALYAQDTYKLTDKLTLTAGLRYDyvsy 384
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 565 -------GASQLWGTDNAWGLFPSISVGWRITeeafmknqkifDDLKLRVGYGvTGSQPkdpflgvamlkyGSYAFVNGN 637
Cdd:COG1629 385 dvddtvtGTDSASGSRSYSAFSPSLGLTYQLS-----------PNLSLYASYS-RGFRA------------PTFGELYAN 440
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 638 wvqTIVPASNPNPDLKWEEKKETNIGLDFVSWGGRLSGSIDYYNRDVDGLIYEYGVPTPPNLYNkTMANGGTMRNRGvev 717
Cdd:COG1629 441 ---GTDPYSVGNPDLKPETSTNYELGLRYRLLDGRLSLSLALFYSDVDNEILSVPLPNDSGFST-YYTNAGKARSYG--- 513
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|..
gi 492458075 718 lvtvvpvqnkdFEWSTTGTFSLNSNklISLSGSIFKSDYDYFNTGTVEYSGQ 769
Cdd:COG1629 514 -----------VELELSYQLTPGLS--LNASYSYTDAKFDDDTDGSADLDGN 552
|
|
| FepA |
COG4771 |
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ... |
92-714 |
3.37e-40 |
|
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];
Pssm-ID: 443803 [Multi-domain] Cd Length: 612 Bit Score: 158.10 E-value: 3.37e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 92 LKEDTKTLDEVVVIGYGTQRK-GDVTSSVASVKADNFVKGAVKDVGQLIQgKVAGLAITNpNGDPTGSTQIRLRGtntIG 170
Cdd:COG4771 20 LAEDATELEEVVVTATRTEQSlSDAPASVSVITAEEIEKLGATDLADALR-LLPGVSVTR-SGGRGGSSGISIRG---LG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 171 GANTapLVLIDGIP---------GELGTVAPEDVESVDVLKdGSAAAIYGTRGTNGVILITTKQAKGvdinqvEYNGYVS 241
Cdd:COG4771 95 GDRV--LVLIDGVPvnnpalgggGDLSYIPPDDIERIEVIR-GPASALYGSDAIGGVINIITKKPTD------ELEGSVS 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 242 TSliakkldmlnadefrtlYPDQDHGADTdwideisrtpvshvHNLSLMGGNSKTNYIANLNYASRQGImKKSDFESFQG 321
Cdd:COG4771 166 LG-----------------YGSNGNGTYS--------------GSLSLGGPGDKLSFLLSGSYRDRDGY-LDYRNGGFVG 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 322 RIEVTHRMFDDKLKLKFGlfgkkNQMESTTSGGSFRGWVYGQATRRNPTDPVRNEDGTWNENVSKFEYenplallyeaeg 401
Cdd:COG4771 214 NSGYERYNLNAKLGYRLS-----DNHRLSLSGGYSRQDRDGGPPTLGDTEISSDNAGDRDTTTDRGNY------------ 276
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 402 nvkktQLRYNGNIvynpikDLTLSAVFSYIRDNMNRGYGETLNHISALRDglagwSSVGAYTkmeklmeLTAQYNKEIG- 480
Cdd:COG4771 277 -----SLRYNGDL------GDNLDLSLYYSRTDRDSTNGSLGGSTGSFSD-----SDDTTYG-------LELDLTYPLGg 333
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 481 AHKFSVlgGYSYNETDFEElwiDNYGFQDDYFggwhnigigsalkdgkanigskktpTNLIGFFGRATYSFKNRYLLMGA 560
Cdd:COG4771 334 NHTLTL--GAEYRYDDLDS---SSFLGGADAS-------------------------RDTYGLFAQDEWKLTDKLTLTAG 383
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 561 LRYEGASQLwGTDNAWGLFPSISVGWRITeeafmknqkifDDLKLRVGYGVTGSQPkdpflgvamlkygSYAFVNGNWVQ 640
Cdd:COG4771 384 LRYDYYSTF-GASNYTAFSPRLGLRYDLS-----------DNLTLRASYGRGFRAP-------------SLAELYGSGTG 438
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492458075 641 TIVPASNPNPDLKWEEKKETNIGLDFVSWGGRLSGSIDYYNRDVDGLIYEYGVPTPPNLYNkTMANGGTMRNRG 714
Cdd:COG4771 439 TPGRYVLGNPDLKPETSDNYELGLEYRLGNGGLSLSLTGFYTDIKDLIVLVPVGPGPGDVL-QYENVGKARTYG 511
|
|
| BtuB |
COG4206 |
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism]; |
102-298 |
3.19e-27 |
|
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
Pssm-ID: 443355 [Multi-domain] Cd Length: 276 Bit Score: 112.27 E-value: 3.19e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 102 VVVIGYG-TQRKGDVTSSVASVKADNFVKGAVKDVGQLIQgKVAGLAITNpNGDPTGSTQIRLRGTNTigganTAPLVLI 180
Cdd:COG4206 1 VVVTATRlEQSKSDLTGSVTVIDAEELERSGATSLADALR-RVPGVQVSS-SGGPGSAASISIRGLGS-----NQTLVLI 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 181 DGIP--------GELGTVAPEDVESVDVLKdGSAAAIYGTRGTNGVILITTKQAKGVDINQVEY--------NGYVSTSL 244
Cdd:COG4206 74 DGVPlndpslggVDLSLIPPDDIERIEVLK-GAASALYGSDAIGGVINITTKKGKKGFKGSVSAsygsfgtrRLSASLSG 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492458075 245 IAKKLD-MLNADEFRT--LYPDQDHGADTDWIDEIS-----RTPVSHVHNLSLMGGNSKTNY 298
Cdd:COG4206 153 GAGKFSySLSASYRRSdgYRYNDPDLRNNDGYENTSlnarlGYKLGDNGSLSLSGGYSDSER 214
|
|
| CarbopepD_reg_2 |
pfam13715 |
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ... |
23-104 |
2.24e-19 |
|
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.
Pssm-ID: 433425 [Multi-domain] Cd Length: 88 Bit Score: 83.41 E-value: 2.24e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 23 VTGKVKD-SSGEPVIGASVVVKGNNTmGTITDFDGNFML-DVPAKSV-LVISYIGYVTQEVP-TAGKNS---LEIVLKED 95
Cdd:pfam13715 1 ISGTVVDeNTGEPLPGATVYVKGTTK-GTVTDADGNFELkNLPAGTYtLVVSFVGYKTQEKKvTVSNDNtldVNFLLKED 79
|
....*....
gi 492458075 96 TKTLDEVVV 104
Cdd:pfam13715 80 ALLLDEVVV 88
|
|
| Plug |
pfam07715 |
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ... |
114-218 |
1.54e-15 |
|
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Pssm-ID: 462243 [Multi-domain] Cd Length: 107 Bit Score: 73.46 E-value: 1.54e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 114 DVTSSVASVKADNFVKGAVKDVGQLIQGkVAGLAITNPNGDptGSTQIRLRGTNTigganTAPLVLIDGIP--------G 185
Cdd:pfam07715 4 DTPGSVSVVTAEDIEDQGATNLADALRG-VPGVSVSSGGGG--GGSSISIRGFGS-----NRVLVLVDGVPlnsggggsV 75
|
90 100 110
....*....|....*....|....*....|...
gi 492458075 186 ELGTVAPEDVESVDVLKdGSAAAIYGTRGTNGV 218
Cdd:pfam07715 76 DLNSIDPEDIERVEVLK-GPASALYGSGAIGGV 107
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
118-714 |
1.14e-14 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 78.26 E-value: 1.14e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 118 SVASVKADNFVKGAVKDVGQLIQgKVAGLAITNPNGDptGSTQIRLRGTntiGGANTapLVLIDGIP---------GELG 188
Cdd:cd01347 1 SVSVITAEDIEKQPATSLADLLR-RIPGVSVTRGGGG--GGSTISIRGF---GPDRT--LVLVDGLPlassnygrgVDLN 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 189 TVAPEDVESVDVLKdGSAAAIYGTRGTNGVILITTKQAKGVDINQVEYnGYvstsliakkldmlNADEFRTLYPDQ-DHG 267
Cdd:cd01347 73 TIPPELIERVEVLK-GPSSALYGSGAIGGVVNIITKRPTDEFGGSVTA-GY-------------GSDNSGSSGGGGfDVS 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 268 ADTDWIDEIS-RTPVSHVHNLSLMGGNSKTNYIANlnyaSRQGIMKKSDFEsfqgrievthrmFDDKLKLKFGLFGKKNQ 346
Cdd:cd01347 138 GALADDGAFGaRLYGAYRDGDGTIDGDGQADDSDE----ERYNVAGKLDWR------------PDDDTRLTLDAGYQDQD 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 347 MESTTSGGSFRGwvyGQATRRNPTDPVRNEDGTWNENVSkfeYENPLALLYEAEGNvkktqlryngnivynpIKDLTLSA 426
Cdd:cd01347 202 ADGPGGTLPANG---TGSSLGGGPSSNTNGDRDWDYRDR---YRKRASLGLEHDLN----------------DTGWTLRA 259
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 427 VFSYIRDNMNRgygETLNHISALRDGLAGWSSVGAYTKMEKLME-LTAQYNKEIGAH--KFSVLGGYSYNETDFEElwid 503
Cdd:cd01347 260 NLSYSYTDNDG---DPLILNGGNNAAGGDLGRSGYSSERDTTQLgFDAGLNAPFGTGpvAHTLTLGVEYRREELDE---- 332
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 504 nygfqddyfggwhnigigsalkdgkanigskktptNLIGFFGRATYSFKNRYLLMGALRYE-----------GASQLWGT 572
Cdd:cd01347 333 -----------------------------------KQTALYAQDTIELTDDLTLTLGLRYDhydqdskdtiaGGTTAKKS 377
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 573 DNAWGlfPSISVGWRITeeafmknqkifDDLKLRVGYGvTGSQPKDPflgvamlkYGSYAFVNgnwvqTIVPASNPNPDL 652
Cdd:cd01347 378 YSHWS--PSLGLVYKLT-----------DGLSLYASYS-QGFRAPSL--------GELYGGGS-----HGGTAAVGNPNL 430
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492458075 653 KWEEKKETNIGLDFvSWGGRLSGSIDYYNRDVDGLIYEYGVPTPPNLYNkTMANGGTMRNRG 714
Cdd:cd01347 431 KPEKSKQYELGLKY-DPGDGLTLSAALFRIDIKNEIVSTPTNTGLGLVT-VYVNGGKARIRG 490
|
|
| TonB_dep_Rec |
pfam00593 |
TonB dependent receptor; This model now only covers the conserved part of the barrel structure. |
361-714 |
3.06e-13 |
|
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain] Cd Length: 475 Bit Score: 73.27 E-value: 3.06e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 361 YGQATRRNPTDPVRNEDGTWNENVSKFEYENPLALLYEAEGNVKKTQLRYNGNIVYNPIKDLTLSAVFSYIRD------- 433
Cdd:pfam00593 2 WQLSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGlswlstl 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 434 NMNRGYGETLNHISALRDGLAGWSSVGAYTKMEKLMELTAQYNKEIGAHKFSVLGG-YSYNETDFEELWIDNYGFQDDYF 512
Cdd:pfam00593 82 RLGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVeLRTAGLDYRRLDDDAYDPYDPAN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 513 GgwhnigigsalkdgkANIGSKKTPTNLIGFFGRATYSFKNRYLLMGALRYEGASQLWGTDNA---------WGLFPSIS 583
Cdd:pfam00593 162 P---------------SSSSYSDTTTDSYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGDDGNGggdnfsrsySAFSPRLG 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 584 VGWRITeeafmknqkifDDLKLRVGYGVTGSQPkdpflgvamlkyGSYAFVNGNWVQTIVPASNPNPDLKWEEKKETNIG 663
Cdd:pfam00593 227 LVYKPT-----------DNLSLYASYSRGFRAP------------SLGELYGSGSGGGGGAVAGGNPDLKPETSDNYELG 283
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 492458075 664 LDFvsWGGRLSGSIDYYNRDVDGLIYEYGVPTPPNLYNKTMANGGTMRNRG 714
Cdd:pfam00593 284 LKY--DDGRLSLSLALFYIDIKNLITSDPDGPGLGGTVYTYTNVGKARIRG 332
|
|
| SusC_RagA_signa |
TIGR04057 |
TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model ... |
194-224 |
2.18e-12 |
|
TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model describes a 31-residue signature region of the SusC/RagA family of outer membrane proteins from the Bacteriodetes. While many TonB-dependent outer membrane receptors are associated with siderophore import, this family seems to include generalized nutrient receptors that may convey fairly large oligomers of protein or carbohydrate. This family occurs in high copy numbers in the most abundant species of the human gut microbiome.
Pssm-ID: 274949 [Multi-domain] Cd Length: 31 Bit Score: 61.83 E-value: 2.18e-12
10 20 30
....*....|....*....|....*....|.
gi 492458075 194 DVESVDVLKDGSAAAIYGTRGTNGVILITTK 224
Cdd:TIGR04057 1 DIESISVLKDASAAAIYGSRGANGVILITTK 31
|
|
| CarboxypepD_reg |
pfam13620 |
Carboxypeptidase regulatory-like domain; |
23-92 |
2.19e-09 |
|
Carboxypeptidase regulatory-like domain;
Pssm-ID: 433354 [Multi-domain] Cd Length: 81 Bit Score: 54.98 E-value: 2.19e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 23 VTGKVKDSSGEPVIGASVVVKGNNT---MGTITDFDGNFML-DVPAKS-VLVISYIGYVTQEVP----TAGKNS-LEIVL 92
Cdd:pfam13620 2 ISGTVTDPSGAPVPGATVTVTNTDTgtvRTTTTDADGRYRFpGLPPGTyTVTVSAPGFKTATRTgvtvTAGQTTtLDVTL 81
|
|
| TonB-siderophor |
TIGR01783 |
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ... |
114-228 |
7.02e-08 |
|
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain] Cd Length: 651 Bit Score: 56.27 E-value: 7.02e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 114 DVTSSVASVKADNFVKGAVKDVGQLIQGKVAGLAITNPNGDPTGStqIRLRGTNTIGGANTaplVLIDGIP----GELGT 189
Cdd:TIGR01783 1 DIPQSVSVITRQELEDQQAGSLSEALQRVPGVVVGGSGGTTQFGN--ITIRGFGLEVDIDN---VYLDGVPllsrGNLAI 75
|
90 100 110
....*....|....*....|....*....|....*....
gi 492458075 190 VAPEDVESVDVLKdGSAAAIYGTRGTNGVILITTKQAKG 228
Cdd:TIGR01783 76 VDPAMVERVEVLR-GPASLLYGGSAPGGVINIVTKRPQD 113
|
|
| FecA |
COG4772 |
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; |
94-226 |
1.48e-07 |
|
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
Pssm-ID: 443804 [Multi-domain] Cd Length: 681 Bit Score: 55.32 E-value: 1.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 94 EDTKTLDEVVVIGYGTQRKG--DVTSSVASVKADNFVKGAVKDVGQLIQgKVAGLAITNPNGdpTG-STQIRLRGTNTIG 170
Cdd:COG4772 18 EAATTLETVVVTGSRAAEARlkDVPGSVSVVDREELENQAATSLREVLR-RVPGVNVQEEDG--FGlRPNIGIRGLGPRR 94
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492458075 171 GANTapLVLIDGIP--------GELG-TVAPEDVESVDVLKdGSAAAIYGTRGTNGVILITTKQA 226
Cdd:COG4772 95 SRGI--TLLEDGIPiapapygdPAAYyFPDLERMERIEVLR-GAAALRYGPQTVGGAINFVTRTI 156
|
|
| Fiu |
COG4774 |
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; |
143-235 |
4.17e-06 |
|
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
Pssm-ID: 443806 [Multi-domain] Cd Length: 639 Bit Score: 50.65 E-value: 4.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 143 VAGlaITNPNGDPTGSTQIRLRGTNTIGGantaplVLIDGIP-GELGTVAPEDVESVDVLKdGSAAAIYGTRGTNGVILI 221
Cdd:COG4774 36 VPG--VTFGAGEGGNGDSFSIRGFSASGD------IYVDGLRdPGQYRRDTFNLERVEVLK-GPASVLYGRGSPGGVINL 106
|
90
....*....|....
gi 492458075 222 TTKQAKGVDINQVE 235
Cdd:COG4774 107 VTKRPTDEPFTEVT 120
|
|
| PRK13528 |
PRK13528 |
outer membrane receptor FepA; Provisional |
132-225 |
1.63e-05 |
|
outer membrane receptor FepA; Provisional
Pssm-ID: 237413 [Multi-domain] Cd Length: 727 Bit Score: 48.98 E-value: 1.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 132 VKDVGQLIQgKVAGLAIT--NPNGDPTGSTQIRLRGtntIGGANTapLVLIDGIP------------GELGT------VA 191
Cdd:PRK13528 67 VNDLSDIIR-KMPGVNLTgnSASGTRGNNRQIDIRG---MGPENT--LILIDGVPvtsrnsvryswrGERDTrgdtnwVP 140
|
90 100 110
....*....|....*....|....*....|....
gi 492458075 192 PEDVESVDVLKdGSAAAIYGTRGTNGVILITTKQ 225
Cdd:PRK13528 141 PEMVERIEVIR-GPAAARYGSGAAGGVVNIITKR 173
|
|
| PRK13524 |
PRK13524 |
FepA family TonB-dependent siderophore receptor; |
160-226 |
2.69e-05 |
|
FepA family TonB-dependent siderophore receptor;
Pssm-ID: 237410 [Multi-domain] Cd Length: 744 Bit Score: 48.10 E-value: 2.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 160 QIRLRGtntIGGANTapLVLIDGIP------------------GELGTVAPEDVESVDVLKdGSAAAIYGTRGTNGVILI 221
Cdd:PRK13524 98 QIDIRG---MGPENT--LILIDGKPvssrnsvrygwrgerdtrGDTNWVPPEMIERIEVLR-GPAAARYGNGAAGGVVNI 171
|
....*
gi 492458075 222 TTKQA 226
Cdd:PRK13524 172 ITKKP 176
|
|
| PRK13484 |
PRK13484 |
IreA family TonB-dependent siderophore receptor; |
97-241 |
1.24e-03 |
|
IreA family TonB-dependent siderophore receptor;
Pssm-ID: 139605 [Multi-domain] Cd Length: 682 Bit Score: 42.69 E-value: 1.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 97 KTLDEVVVIGYG-TQRKGDVTSSVASVKADNFVKGAVKDVGQLIQGkVAGLAITNPNGDPtgstQIRLRGtntIGGANTa 175
Cdd:PRK13484 28 KKEDTLVVTASGfTQQLRNAPASVSVITSEQLQKKPVSDLVDAVKD-VEGISITGGNEKP----DISIRG---LSGDYT- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492458075 176 pLVLIDGI--------PG-----ELGTVAPED-VESVDVLKdGSAAAIYGTRGTNGVILITTKQakgvdINQVEYNGYVS 241
Cdd:PRK13484 99 -LILVDGRrqsgresrPNgsggfEAGFIPPVEaIERIEVIR-GPMSSLYGSDAIGGVINIITKP-----VNNQTWDGVLG 171
|
|
| |
