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Conserved domains on  [gi|492395704|ref|WP_005830921|]
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MULTISPECIES: phosphatase PAP2 family protein [Bacteroides]

Protein Classification

PgpB family protein( domain architecture ID 11430553)

PgpB family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 1-173 3.47e-25

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


:

Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 96.65  E-value: 3.47e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704   1 MKKAIFFVYFICLVVSGLSAQNWDINTLHRVNSWDgkFVRNYNKIISRSEPYVAVGVPVAMAVAAWIKHDKGLLKDAVYV 80
Cdd:COG0671    1 LLLALLLALLLLLLLLADLLALALLALLLLLALLL--LLLLLLALLLILLLLLLLLLLLLLLLLLLLRLLALLLLLLLLA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704  81 GTSVAGAFVVTYGMKYLVDRERPYDkYPDRVHAYSHEGSPSFPSGHTATAFALATSLSVKYPKWYVIAPSALWACSVGVS 160
Cdd:COG0671   79 ALLLLLLLLLLLLLKYLFGRPRPFV-VPDLELLLGTAGGYSFPSGHAAAAFALALVLALLLPRRWLAALLLALALLVGLS 157

                        170
                 ....*....|...
gi 492395704 161 RMNEGVHYPSDVL 173
Cdd:COG0671  158 RVYLGVHYPSDVL 170
 
Name Accession Description Interval E-value
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 1-173 3.47e-25

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 96.65  E-value: 3.47e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704   1 MKKAIFFVYFICLVVSGLSAQNWDINTLHRVNSWDgkFVRNYNKIISRSEPYVAVGVPVAMAVAAWIKHDKGLLKDAVYV 80
Cdd:COG0671    1 LLLALLLALLLLLLLLADLLALALLALLLLLALLL--LLLLLLALLLILLLLLLLLLLLLLLLLLLLRLLALLLLLLLLA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704  81 GTSVAGAFVVTYGMKYLVDRERPYDkYPDRVHAYSHEGSPSFPSGHTATAFALATSLSVKYPKWYVIAPSALWACSVGVS 160
Cdd:COG0671   79 ALLLLLLLLLLLLLKYLFGRPRPFV-VPDLELLLGTAGGYSFPSGHAAAAFALALVLALLLPRRWLAALLLALALLVGLS 157

                        170
                 ....*....|...
gi 492395704 161 RMNEGVHYPSDVL 173
Cdd:COG0671  158 RVYLGVHYPSDVL 170
PAP2_like_2 cd03392
PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 51-173 1.15e-22

PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239486  Cd Length: 182  Bit Score: 89.98  E-value: 1.15e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704  51 PYVAVGVPVAMAVAAWIKHDKgllKDAVYVGTSVAGAFVVTYGMKYLVDRERPydkypdRVHAYSHEGSPSFPSGHTATA 130
Cdd:cd03392   41 PAVLLIIVLLLALLLLLKRRR---RAALFLLLALLGGGALNTLLKLLVQRPRP------PLHLLVPEGGYSFPSGHAMGA 111

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 492395704 131 FALATSLSV--------KYPKWYVIAPSALWACSVGVSRMNEGVHYPSDVL 173
Cdd:cd03392  112 TVLYGFLAYllarrlprRRVRILLLILAAILILLVGLSRLYLGVHYPSDVL 162
acidPPc smart00014
Acid phosphatase homologues;
93-173 2.56e-15

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 68.91  E-value: 2.56e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704    93 GMKYLVDRERPYDKYPDRV-----HAYSHEGSPSFPSGHTATAFALATSLSVKYPKWY----VIAPSALWACSVGVSRMN 163
Cdd:smart00014  13 VIKNYFGRPRPFFLSIGDAcctpnFLLTLEAGYSFPSGHTAFAFAFALFLLLYLPARAgrklLIFLLLLLALVVGFSRVY 92

                           90
                   ....*....|
gi 492395704   164 EGVHYPSDVL 173
Cdd:smart00014  93 LGAHWPSDVL 102
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 79-173 2.10e-13

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 63.98  E-value: 2.10e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704   79 YVGTSVAGAFVVTYGMKYLVDRERPY----DKYPDRVHAYSHEGSPSFPSGHTATAFALATSLSVKYPKWYVIAPSAL-- 152
Cdd:pfam01569   1 ILLLALALAGLLSSVLKDYFGRPRPFflllEGGLVPAPSTLPGLGYSFPSGHSATAFALALLLALLLRRLRKIVRVLLal 80

                          90       100
                  ....*....|....*....|....*
gi 492395704  153 ----WACSVGVSRMNEGVHYPSDVL 173
Cdd:pfam01569  81 lllvLALLVGLSRLYLGVHFPSDVL 105
PRK10699 PRK10699
phosphatidylglycerophosphatase B; Provisional
 121-172 1.21e-03

phosphatidylglycerophosphatase B; Provisional


Pssm-ID: 182658  Cd Length: 244  Bit Score: 38.47  E-value: 1.21e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 492395704 121 SFPSGHT---ATAFALATSLSVKYPKWYVIAPSALWACSVGVSRMNEGVHYPSDV 172
Cdd:PRK10699 158 AFPSGHTmfaASWALLAVGLLWPRRRYKTVALLMLWATGVMGSRLLLGMHWPRDL 212
 
Name Accession Description Interval E-value
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 1-173 3.47e-25

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 96.65  E-value: 3.47e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704   1 MKKAIFFVYFICLVVSGLSAQNWDINTLHRVNSWDgkFVRNYNKIISRSEPYVAVGVPVAMAVAAWIKHDKGLLKDAVYV 80
Cdd:COG0671    1 LLLALLLALLLLLLLLADLLALALLALLLLLALLL--LLLLLLALLLILLLLLLLLLLLLLLLLLLLRLLALLLLLLLLA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704  81 GTSVAGAFVVTYGMKYLVDRERPYDkYPDRVHAYSHEGSPSFPSGHTATAFALATSLSVKYPKWYVIAPSALWACSVGVS 160
Cdd:COG0671   79 ALLLLLLLLLLLLLKYLFGRPRPFV-VPDLELLLGTAGGYSFPSGHAAAAFALALVLALLLPRRWLAALLLALALLVGLS 157

                        170
                 ....*....|...
gi 492395704 161 RMNEGVHYPSDVL 173
Cdd:COG0671  158 RVYLGVHYPSDVL 170
PAP2_like_2 cd03392
PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 51-173 1.15e-22

PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239486  Cd Length: 182  Bit Score: 89.98  E-value: 1.15e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704  51 PYVAVGVPVAMAVAAWIKHDKgllKDAVYVGTSVAGAFVVTYGMKYLVDRERPydkypdRVHAYSHEGSPSFPSGHTATA 130
Cdd:cd03392   41 PAVLLIIVLLLALLLLLKRRR---RAALFLLLALLGGGALNTLLKLLVQRPRP------PLHLLVPEGGYSFPSGHAMGA 111

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 492395704 131 FALATSLSV--------KYPKWYVIAPSALWACSVGVSRMNEGVHYPSDVL 173
Cdd:cd03392  112 TVLYGFLAYllarrlprRRVRILLLILAAILILLVGLSRLYLGVHYPSDVL 162
PAP2_like_5 cd03394
PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 75-173 4.65e-21

PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239488 [Multi-domain]  Cd Length: 106  Bit Score: 83.53  E-value: 4.65e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704  75 KDAVYVGTSVAGAFVVTYGMKYLVDRERPYDkypdrvhaySHEGSPSFPSGHTATAFALATSLSVKYPKWYVIAPSALWA 154
Cdd:cd03394    3 EGLLILAEAAALTAAVTEGLKFAVGRARPDG---------SNNGYRSFPSGHTASAFAAATFLQYRYGWRWYGIPAYALA 73

                         90
                 ....*....|....*....
gi 492395704 155 CSVGVSRMNEGVHYPSDVL 173
Cdd:cd03394   74 SLVGASRVVANRHWLSDVL 92
PAP2_like cd01610
PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, ...
 77-173 2.59e-20

PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid phosphatase, vanadium chloroperoxidases, vanadium bromoperoxidases, and several other mostly uncharacterized subfamilies. Several members of this superfamily have been predicted to be transmembrane proteins.


Pssm-ID: 238813 [Multi-domain]  Cd Length: 122  Bit Score: 82.12  E-value: 2.59e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704  77 AVYVGTSVAGAFVVTYGMKYLVDRERPY---DKYPDRVHAYSHEGSPSFPSGHTATAFALATSLSV----KYPKWYVIAP 149
Cdd:cd01610    5 ALLLLLALLAGLLLTGVLKYLFGRPRPYfllRCGPDGDPLLLTEGGYSFPSGHAAFAFALALFLALllprRLLRLLLGLL 84

                         90       100
                 ....*....|....*....|....
gi 492395704 150 SALWACSVGVSRMNEGVHYPSDVL 173
Cdd:cd01610   85 LLLLALLVGLSRVYLGVHYPSDVL 108
acidPPc smart00014
Acid phosphatase homologues;
93-173 2.56e-15

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 68.91  E-value: 2.56e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704    93 GMKYLVDRERPYDKYPDRV-----HAYSHEGSPSFPSGHTATAFALATSLSVKYPKWY----VIAPSALWACSVGVSRMN 163
Cdd:smart00014  13 VIKNYFGRPRPFFLSIGDAcctpnFLLTLEAGYSFPSGHTAFAFAFALFLLLYLPARAgrklLIFLLLLLALVVGFSRVY 92

                           90
                   ....*....|
gi 492395704   164 EGVHYPSDVL 173
Cdd:smart00014  93 LGAHWPSDVL 102
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 79-173 2.10e-13

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 63.98  E-value: 2.10e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704   79 YVGTSVAGAFVVTYGMKYLVDRERPY----DKYPDRVHAYSHEGSPSFPSGHTATAFALATSLSVKYPKWYVIAPSAL-- 152
Cdd:pfam01569   1 ILLLALALAGLLSSVLKDYFGRPRPFflllEGGLVPAPSTLPGLGYSFPSGHSATAFALALLLALLLRRLRKIVRVLLal 80

                          90       100
                  ....*....|....*....|....*
gi 492395704  153 ----WACSVGVSRMNEGVHYPSDVL 173
Cdd:pfam01569  81 lllvLALLVGLSRLYLGVHFPSDVL 105
PAP2_like_4 cd03395
PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 94-173 3.42e-12

PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239489  Cd Length: 177  Bit Score: 61.90  E-value: 3.42e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704  94 MKYLVDRERP--------YDKYPDRVHAYShegspsFPSGHTATAFALATSLSVKYPKWYVIAPSALWACSVGVSRMNEG 165
Cdd:cd03395   76 LKPLVARLRPcnaldgvrLVVLGDQGGSYS------FASSHAANSFALALFIWLFFRRGLFSPVLLLWALLVGYSRVYVG 149


                 ....*...
gi 492395704 166 VHYPSDVL 173
Cdd:cd03395  150 VHYPGDVI 157
PAP2_lipid_A_1_phosphatase cd03389
PAP2_like proteins, Lipid A 1-phosphatase subfamily. Lipid A 1-phosphatase, or LpxE from ...
 77-173 1.36e-11

PAP2_like proteins, Lipid A 1-phosphatase subfamily. Lipid A 1-phosphatase, or LpxE from Francisella novicida selectively dephosphorylates lipid A at the 1-position. Lipid A is the membrane-anchor component of lipopolysaccharides (LPS), the major constituents of the outer membrane in many gram-negative bacteria.


Pssm-ID: 239483  Cd Length: 186  Bit Score: 60.41  E-value: 1.36e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704  77 AVYVGTSVAGAFVVTYGMKYLVDRERP--------YDKYPDRV-HAYShegspSFPSGHTATAFALATSLSVKYPKWYVI 147
Cdd:cd03389   71 GLFLFATVALSGILVNLLKFIIGRARPkllfddglYGFDPFHAdYAFT-----SFPSGHSATAGAAAAALALLFPRYRWA 145

                         90       100
                 ....*....|....*....|....*.
gi 492395704 148 ApsALWACSVGVSRMNEGVHYPSDVL 173
Cdd:cd03389  146 F--ILLALLIAFSRVIVGAHYPSDVI 169
PAP2_like_1 cd03380
PAP2_like_1 proteins, a sub-family of PAP2, containing bacterial acid phosphatase, vanadium ...
 89-172 2.92e-10

PAP2_like_1 proteins, a sub-family of PAP2, containing bacterial acid phosphatase, vanadium chloroperoxidases and vanadium bromoperoxidases.


Pssm-ID: 239475  Cd Length: 209  Bit Score: 57.44  E-value: 2.92e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704  89 VVTYGMKYLVDRERPY--DKYPDRVHAYSHEG---SPSFPSGHTATAFALATSLSVKYPKWYviapSALWACS--VGVSR 161
Cdd:cd03380  107 IATWDAKYHYNRPRPFvaIRLQWLPICTPEEGtpkHPSYPSGHATFGGAAALVLAELFPERA----AELLARAaeAGNSR 182

                         90
                 ....*....|.
gi 492395704 162 MNEGVHYPSDV 172
Cdd:cd03380  183 VVAGVHWPSDV 193
PAP2_BcrC_like cd03385
PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as ...
 52-173 2.01e-09

PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from Bacillus subtilis posesses undecaprenyl pyrophosphate (UPP) phospatase activity, and it is hypothesized that it competes with bacitracin for UPP, increasing the cell's resistance to bacitracin.


Pssm-ID: 239480  Cd Length: 144  Bit Score: 53.80  E-value: 2.01e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704  52 YVAVGVPVAMaVAAWIKHDKGLLKDAVYVGTSVAGAFVVTYGMKYLVDRERPYDKYPDRVHAYsHEGSPSFPSGHTATAF 131
Cdd:cd03385   11 YLIYILPLLL-VVLWLWGGEKQRKVVLFATIAVAVALLINYIIGLLYFHPRPFVVGLGHNLLP-HAADSSFPSDHTTLFF 88

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 492395704 132 ALATS-LSVKYPKWYVIApsALWACSVGVSRMNEGVHYPSDVL 173
Cdd:cd03385   89 SIAFSlLLRRRKWAGWIL--LILALLVAWSRIYLGVHYPLDML 129
PAP2_containing_2_like cd03391
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. ...
 72-173 3.77e-08

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to eukaryota, lacks functional characterization and may act as a membrane-associated phosphatidic acid phosphatase.


Pssm-ID: 239485 [Multi-domain]  Cd Length: 159  Bit Score: 50.78  E-value: 3.77e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704  72 GLLKDAVYVGtsvagafvvtyGMKYLVDRERPYDKYPDRVHAYSHEgSPSFPSGHTATAFALATSLSVKYP-KWYVIAPS 150
Cdd:cd03391   55 GLLLDIITVA-----------ILKALVRRRRPAYNSPDMLDYVAVD-KYSFPSGHASRAAFVARFLLNHLVlAVPLRVLL 122

                         90       100
                 ....*....|....*....|...
gi 492395704 151 ALWACSVGVSRMNEGVHYPSDVL 173
Cdd:cd03391  123 VLWATVVGISRVLLGRHHVLDVL 145
PAP2_like_3 cd03393
PAP2_like_3 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 77-173 3.21e-07

PAP2_like_3 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria and archaea, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239487 [Multi-domain]  Cd Length: 125  Bit Score: 47.37  E-value: 3.21e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704  77 AVYVGTSVAGAFVVTYGMKYLVDRERPYDKYPDRVHAYSHEGSPSFPSGHTATAFALATSLSVKYPKWYVIAPSALWACS 156
Cdd:cd03393   15 GRYLGLALCASGYLNAALKEVFKIPRPFTYDGIQAIYEESAGGYGFPSGHAQTSATFWGSLMLHVRKKWFTLIGVVLVVL 94

                         90
                 ....*....|....*..
gi 492395704 157 VGVSRMNEGVHYPSDVL 173
Cdd:cd03393   95 ISFSRLYLGVHWPSDVI 111
PAP2_acid_phosphatase cd03397
PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes ...
 90-172 6.77e-07

PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains to be determined.


Pssm-ID: 239491  Cd Length: 232  Bit Score: 48.10  E-value: 6.77e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704  90 VTYGMKYLVDRERPYDKYPDRVHAYSHE----GSPSFPSGHTATAFALATSLSVKYPKWYviapSALWACS--VGVSRMN 163
Cdd:cd03397  116 ATYPAKKYYNRPRPFVLNDEPICTPPDEsglaKDGSYPSGHTAAGYAWALILAELVPERA----DEILARGseYGQSRIV 191


                 ....*....
gi 492395704 164 EGVHYPSDV 172
Cdd:cd03397  192 CGVHWPSDV 200
PAP2_like_6 cd03396
PAP2_like_6 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 52-173 2.36e-06

PAP2_like_6 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which mainly contains bacterial proteins, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239490  Cd Length: 197  Bit Score: 46.14  E-value: 2.36e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704  52 YVAVGVPVAMAVAAWIKHDKGLLKDAVYVGTSVAGAFVVTYGMKYLVDRERPYD--------KYPDRVHAYSHEGSP--S 121
Cdd:cd03396   44 ALAVLLLALALLFFRRKRLRRRRRALLLLILVIGLGLLVVAILKSHWGRPRPWDltefggdaPYTPLFSGPSNGCGKgcS 123

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 492395704 122 FPSGHTATAFAL-----ATSLSVKYPKWYVIAPSALWACSVGVSRMNEGVHYPSDVL 173
Cdd:cd03396  124 FPSGHASAGFALlalyfLFRRRRPRLARLVLAAGLALGALMGLARMARGAHFLSDVL 180
PAP2_diacylglycerolkinase cd03383
PAP2_like proteins, diacylglycerol_kinase like sub-family. In some prokaryotes, PAP2_like ...
 111-173 5.18e-06

PAP2_like proteins, diacylglycerol_kinase like sub-family. In some prokaryotes, PAP2_like phosphatase domains appear fused to E. coli DAGK-like trans-membrane diacylglycerol kinase domains. The cellular function of these architectures remains to be determined.


Pssm-ID: 239478 [Multi-domain]  Cd Length: 109  Bit Score: 43.86  E-value: 5.18e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492395704 111 VHAYSHEGSP---SFPSGHTATAFALATSLSVKYPKWYVIAPSALWACSVGVSRMNEGVHYPSDVL 173
Cdd:cd03383   27 LKAYFGRGTPlegGMPSGHAAIAFSIATAISLITNNPIISILSVLLAVMVAHSRVEMKIHTMWEVV 92
COG3907 COG3907
Membrane-associated enzyme, PAP2 (acid phosphatase) superfamily [General function prediction ...
 51-173 2.55e-05

Membrane-associated enzyme, PAP2 (acid phosphatase) superfamily [General function prediction only];


Pssm-ID: 443113  Cd Length: 236  Bit Score: 43.35  E-value: 2.55e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704  51 PYVAVGVPVAMAVAAWIKHDKGLLK----DAVYVGTSVAGAFVVTYGMKYLVDRERPYD------KYPDRVH--AYSHEG 118
Cdd:COG3907   68 KWLVILVAVLLLLLLLASFKRPRLRryrrRLLYLLLSLALGLLVVSLLKSHTGRPCPWDlvefggDAPYVPLfePGPAGA 147

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492395704 119 SP--SFPSGHTATAFALATSLSVKYPKWYVIAPSALWA-----CSVGVSRMNEGVHYPSDVL 173
Cdd:COG3907  148 GPgrCFPAGHASAGFALLALYFLLRRRRPRLARLGLAAglalgLLMGLAQMLRGAHFLSHTL 209
PAP2_containing_1_like cd03390
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. ...
 53-173 6.71e-05

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both diacylglycerol pyrophosphate phosphatase activity as well as phosphatidate (PA) phosphatase activity, they may have a more generic housekeeping role in lipid metabolism.


Pssm-ID: 239484 [Multi-domain]  Cd Length: 193  Bit Score: 41.82  E-value: 6.71e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704  53 VAVGVPVA-MAVAAWIKHDKGLLKDAVYVGT--SVAGAFVVTYGMKYLVDRERP---------------YDKYPDRVHAY 114
Cdd:cd03390   21 ISVGIPLLvIILISLFFRRSLWDLHTSLLGLllSVSLNGVITNVLKNYAGRPRPdflarcfpdggtpsdTLVGIDICCTG 100

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492395704 115 SH----EGSPSFPSGHTATAFA--------LATSLSVKYPK------WYVIAPSaLWACSVGVSRMNEGVHYPSDVL 173
Cdd:cd03390  101 DPgvlkEGRKSFPSGHSSFAFAglgflslyLAGKLHIFDPRgsswrlLLALLPL-LLAILVAVSRTRDYRHHFSDVI 176
PAP2_haloperoxidase cd03398
PAP2, haloperoxidase_like subfamily. Haloperoxidases catalyze the oxidation of halides such as ...
 80-172 7.79e-05

PAP2, haloperoxidase_like subfamily. Haloperoxidases catalyze the oxidation of halides such as bromide or chloride by hydrogen peroxide, which results in subsequent halogenation of organic substrates, or halide-assisted disproportionation of hydrogen peroxide forming dioxygen. They are likely to participate in the biosynthesis of halogenated natural products, such as volatile halogenated hydrocarbons, chiral halogenated terpenes, acetogenins and indoles.


Pssm-ID: 239492  Cd Length: 232  Bit Score: 42.02  E-value: 7.79e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704  80 VGTSVAGAFVVTYGMKYLVDRERP--YDKYPDR-VHAYSHEGS-----------PSFPSGHTATAFALATSLSVKYPKWY 145
Cdd:cd03398   91 VNAAMTDAGIAAWDAKYHYRRWRPvtAIRLADTdGNPATEADPywlplagtpphPSYPSGHATFAGAAATVLKALFGSDK 170

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 492395704 146 VIAPSALWACS-------------------VGVSRMNEGVHYPSDV 172
Cdd:cd03398  171 VPDTVSEPDEGgpstgvtrvwaelneladeVAISRVYAGVHFRSDD 216
PAP2_SPPase1 cd03388
PAP2_like proteins, sphingosine-1-phosphatase subfamily. Sphingosine-1-phosphatase is an ...
 121-172 1.05e-03

PAP2_like proteins, sphingosine-1-phosphatase subfamily. Sphingosine-1-phosphatase is an intracellular enzyme located in the endoplasmic reticulum, which regulates the level of sphingosine-1-phosphate (S1P), a bioactive lipid. S1P acts as a second messenger in the cell, and extracellularly by binding to G-protein coupled receptors of the endothelial differentiation gene family.


Pssm-ID: 239482  Cd Length: 151  Bit Score: 37.98  E-value: 1.05e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 492395704 121 SFPSGHTATAFALATSL------SVKYPKWYVIAPSALWACSVGVSRMNEGVHYPSDV 172
Cdd:cd03388   79 GFPSTHAMNATAISFYLliylydRYQYPFVLGLILALFYSTLVCLSRIYMGMHSVLDV 136
PRK10699 PRK10699
phosphatidylglycerophosphatase B; Provisional
 121-172 1.21e-03

phosphatidylglycerophosphatase B; Provisional


Pssm-ID: 182658  Cd Length: 244  Bit Score: 38.47  E-value: 1.21e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 492395704 121 SFPSGHT---ATAFALATSLSVKYPKWYVIAPSALWACSVGVSRMNEGVHYPSDV 172
Cdd:PRK10699 158 AFPSGHTmfaASWALLAVGLLWPRRRYKTVALLMLWATGVMGSRLLLGMHWPRDL 212
PLN02250 PLN02250
lipid phosphate phosphatase
 43-175 7.09e-03

lipid phosphate phosphatase


Pssm-ID: 215139  Cd Length: 314  Bit Score: 36.44  E-value: 7.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704  43 NKIISRSEPYVAVGVPVA-MAVAAWIKHDKGLLKDAVY-VGTSVAGAFVVTYGMKYLVDRERP---YDKYPDRVHAYS-- 115
Cdd:PLN02250  64 NTIPFWAVPLIAILLPFAvILVYYFIRRDVYDLHHAILgLLFSVLITGVITDAIKDAVGRPRPdffWRCFPDGKGVFHpv 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704 116 -------------HEGSPSFPSGHTATAFA----LATSLSVK---------YPKWYVIAPSALWACSVGVSRMNEGVHYP 169
Cdd:PLN02250 144 ttdvlctgaksviKEGHKSFPSGHTSWSFAglgfLSLYLSGKirvfdrrghVAKLCIVFLPLLVAALVGVSRVDDYWHHW 223


                 ....*.
gi 492395704 170 SDVLAG 175
Cdd:PLN02250 224 QDVFAG 229
PAP2_3 pfam14378
PAP2 superfamily;
52-173 7.53e-03

PAP2 superfamily;


Pssm-ID: 433919  Cd Length: 190  Bit Score: 35.78  E-value: 7.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492395704   52 YVAVGVPVAMAVAAWI-KHDKGLLKDAVyvgTSVAGAFVVTYGMKYLVDRERPY----DKYPDRVHAYSHEGSP------ 120
Cdd:pfam14378  36 YASLHFQVTLAVLVWLfRRRPRRYREFR---TTFLVATLLGLLVFTLFPAAPPRllppAGFVDTVAAASLVGWLrdgtsr 112

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492395704  121 -------------SFPSGHTATAFALATSLSVKYPKWYVIAPSALWACSVGVSRMNEGVHYPSDVL 173
Cdd:pfam14378 113 aplglggitnglaAMPSLHVAWALLCALALWRLRRTRILRWLAVAYNVLMIVSTVATGNHYLLDVV 178
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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