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Conserved domains on  [gi|492358354|ref|WP_005820533|]
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MULTISPECIES: PadR family transcriptional regulator [Bacteroides]

Protein Classification

PadR family transcriptional regulator( domain architecture ID 11447737)

PadR family transcriptional regulator similar to the phenolic acid decarboxylation repressor, which is a transcription factor that represses genes associated with the phenolic acid stress response in gram-positive bacteria

Gene Ontology:  GO:0003677|GO:0003700
PubMed:  10679470|10908318|10473770|15808743|8831795

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
7-104 1.30e-30

DNA-binding transcriptional regulator, PadR family [Transcription];


:

Pssm-ID: 441301  Cd Length: 102  Bit Score: 104.63  E-value: 1.30e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492358354   7 KSQMRKGMLEYCIMLLLHKEPAYASDIIQKLKEA---KLIVVEGTLYPLLTRLKNDDLLSYEWVESTQGPPRKYYKLTEK 83
Cdd:COG1695    2 KRQLRKGTLELLILALLAEGPMYGYEIIKELEERsggFWKVSEGTLYPALKRLEKEGLVESEWEESEGGPRRKYYRLTEA 81

                         90       100
                 ....*....|....*....|.
gi 492358354  84 GELFLGELELSWRELNETVNH 104
Cdd:COG1695   82 GREELAEWLEEWEKLAEALEA 102
 
Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
7-104 1.30e-30

DNA-binding transcriptional regulator, PadR family [Transcription];


Pssm-ID: 441301  Cd Length: 102  Bit Score: 104.63  E-value: 1.30e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492358354   7 KSQMRKGMLEYCIMLLLHKEPAYASDIIQKLKEA---KLIVVEGTLYPLLTRLKNDDLLSYEWVESTQGPPRKYYKLTEK 83
Cdd:COG1695    2 KRQLRKGTLELLILALLAEGPMYGYEIIKELEERsggFWKVSEGTLYPALKRLEKEGLVESEWEESEGGPRRKYYRLTEA 81

                         90       100
                 ....*....|....*....|.
gi 492358354  84 GELFLGELELSWRELNETVNH 104
Cdd:COG1695   82 GREELAEWLEEWEKLAEALEA 102
PadR pfam03551
Transcriptional regulator PadR-like family; Members of this family are transcriptional ...
 19-88 5.61e-17

Transcriptional regulator PadR-like family; Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.


Pssm-ID: 397561  Cd Length: 74  Bit Score: 69.20  E-value: 5.61e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492358354   19 IMLLLHKEPAYASDIIQKLKE---AKLIVVEGTLYPLLTRLKNDDLLSYEWVESTQGPPRKYYKLTEKGELFL 88
Cdd:pfam03551   1 VLAVLGEQPRYGYEIIKELEElsgGFWRPSEGTLYPILKRLEKEGLVESEWVDSGGGPPRKYYRLTDAGRREL 73
padR_acidobact TIGR03433
transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are ...
 12-105 1.25e-10

transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are putative transcriptional regulators of the PadR family, as found in species of the Acidobacteria. This family of proteins has expanded greatly in this lineage, and where it regularly is found in the vicinity of a putative transporter protein [Regulatory functions, DNA interactions]


Pssm-ID: 163261  Cd Length: 100  Bit Score: 53.71  E-value: 1.25e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492358354   12 KGMLEYCIMLLLHKEPAYASDI---IQKLKEAKLIVVEGTLYPLLTRLKNDDLLSYEWVESTQGPPRKYYKLTEKGELFL 88
Cdd:TIGR03433   2 QGTLDLLILKTLSLGPLHGYGIaqrIQQISEDVLQVEEGSLYPALHRLERRGWIAAEWGESENNRRAKFYRLTAAGRKQL 81

                          90
                  ....*....|....*..
gi 492358354   89 GELELSWRELNETVNHI 105
Cdd:TIGR03433  82 AAETESWARLSAAIARV 98
lstR PRK09416
PadR family transcriptional regulator;
4-92 3.11e-05

PadR family transcriptional regulator;


Pssm-ID: 181836  Cd Length: 135  Bit Score: 40.16  E-value: 3.11e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492358354   4 DNVKSQMRKGMLE-----YCIMLLLHKEPA--YASDIIQKLKEAKLIVVEGTLYPLLTRLKNDDLLSYEWVESTQgpprK 76
Cdd:PRK09416  28 KAVREKIKQSSEKeedilLAILQLLMNEKTgyELLQLLRQRGILTFEGNEGSLYTLLHRLEQNRFIQSSWDHEGA----K 103

                         90
                 ....*....|....*.
gi 492358354  77 YYKLTEKGELFLGELE 92
Cdd:PRK09416 104 YYQLTDKGNKMLRKAE 119
HTH_ARSR cd00090
Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric ...
 19-87 4.98e-04

Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.


Pssm-ID: 238042 [Multi-domain]  Cd Length: 78  Bit Score: 36.12  E-value: 4.98e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492358354  19 IMLLLHKEPAYASDIIQKLKeakliVVEGTLYPLLTRLKNDDLlsyewVESTQGPPRKYYKLTEKGELF 87
Cdd:cd00090   12 ILRLLLEGPLTVSELAERLG-----LSQSTVSRHLKKLEEAGL-----VESRREGRRVYYSLTDAERLL 70
 
Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
7-104 1.30e-30

DNA-binding transcriptional regulator, PadR family [Transcription];


Pssm-ID: 441301  Cd Length: 102  Bit Score: 104.63  E-value: 1.30e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492358354   7 KSQMRKGMLEYCIMLLLHKEPAYASDIIQKLKEA---KLIVVEGTLYPLLTRLKNDDLLSYEWVESTQGPPRKYYKLTEK 83
Cdd:COG1695    2 KRQLRKGTLELLILALLAEGPMYGYEIIKELEERsggFWKVSEGTLYPALKRLEKEGLVESEWEESEGGPRRKYYRLTEA 81

                         90       100
                 ....*....|....*....|.
gi 492358354  84 GELFLGELELSWRELNETVNH 104
Cdd:COG1695   82 GREELAEWLEEWEKLAEALEA 102
PadR pfam03551
Transcriptional regulator PadR-like family; Members of this family are transcriptional ...
 19-88 5.61e-17

Transcriptional regulator PadR-like family; Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.


Pssm-ID: 397561  Cd Length: 74  Bit Score: 69.20  E-value: 5.61e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492358354   19 IMLLLHKEPAYASDIIQKLKE---AKLIVVEGTLYPLLTRLKNDDLLSYEWVESTQGPPRKYYKLTEKGELFL 88
Cdd:pfam03551   1 VLAVLGEQPRYGYEIIKELEElsgGFWRPSEGTLYPILKRLEKEGLVESEWVDSGGGPPRKYYRLTDAGRREL 73
padR_acidobact TIGR03433
transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are ...
 12-105 1.25e-10

transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are putative transcriptional regulators of the PadR family, as found in species of the Acidobacteria. This family of proteins has expanded greatly in this lineage, and where it regularly is found in the vicinity of a putative transporter protein [Regulatory functions, DNA interactions]


Pssm-ID: 163261  Cd Length: 100  Bit Score: 53.71  E-value: 1.25e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492358354   12 KGMLEYCIMLLLHKEPAYASDI---IQKLKEAKLIVVEGTLYPLLTRLKNDDLLSYEWVESTQGPPRKYYKLTEKGELFL 88
Cdd:TIGR03433   2 QGTLDLLILKTLSLGPLHGYGIaqrIQQISEDVLQVEEGSLYPALHRLERRGWIAAEWGESENNRRAKFYRLTAAGRKQL 81

                          90
                  ....*....|....*..
gi 492358354   89 GELELSWRELNETVNHI 105
Cdd:TIGR03433  82 AAETESWARLSAAIARV 98
lstR PRK09416
PadR family transcriptional regulator;
4-92 3.11e-05

PadR family transcriptional regulator;


Pssm-ID: 181836  Cd Length: 135  Bit Score: 40.16  E-value: 3.11e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492358354   4 DNVKSQMRKGMLE-----YCIMLLLHKEPA--YASDIIQKLKEAKLIVVEGTLYPLLTRLKNDDLLSYEWVESTQgpprK 76
Cdd:PRK09416  28 KAVREKIKQSSEKeedilLAILQLLMNEKTgyELLQLLRQRGILTFEGNEGSLYTLLHRLEQNRFIQSSWDHEGA----K 103

                         90
                 ....*....|....*.
gi 492358354  77 YYKLTEKGELFLGELE 92
Cdd:PRK09416 104 YYQLTDKGNKMLRKAE 119
HTH_ARSR cd00090
Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric ...
 19-87 4.98e-04

Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.


Pssm-ID: 238042 [Multi-domain]  Cd Length: 78  Bit Score: 36.12  E-value: 4.98e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492358354  19 IMLLLHKEPAYASDIIQKLKeakliVVEGTLYPLLTRLKNDDLlsyewVESTQGPPRKYYKLTEKGELF 87
Cdd:cd00090   12 ILRLLLEGPLTVSELAERLG-----LSQSTVSRHLKKLEEAGL-----VESRREGRRVYYSLTDAERLL 70
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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