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Conserved domains on  [gi|492291028|ref|WP_005800114|]
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pyridoxal phosphate-dependent aminotransferase [Bacteroides fragilis]

Protein Classification

pyridoxal phosphate-dependent aminotransferase( domain architecture ID 1905206)

pyridoxal phosphate (PLP)-dependent aminotransferase catalyzes the reversible exchange of an amino group from one molecule with a keto group from another molecule, an important reaction in the synthesis or degradation of amino acids

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
AspB super family cl43143
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ...
 28-435 9.06e-44

Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis


The actual alignment was detected with superfamily member COG0436:

Pssm-ID: 440205 [Multi-domain]  Cd Length: 387  Bit Score: 157.60  E-value: 9.06e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  28 IREVKAIAAKAEtASGVEFIKMEMGVPGLPPSTVGVKAEIEALQNGiASLYPDINGLPELKSEASKFIKAFIDIDLKPEG 107
Cdd:COG0436   15 IREVSALAAELK-AAGEDVIDLGIGEPDFPTPDHIREAAIEALDDG-VTGYTPSAGIPELREAIAAYYKRRYGVDLDPDE 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 108 CVPVTGSMQGTFASFLTCsqCDEKkDTILFIDPGFPVQKQQLVVMGQKYETFDVYDYRGDKLK-EKLESYLKKgNISAVI 186
Cdd:COG0436   93 ILVTNGAKEALALALLAL--LNPG-DEVLVPDPGYPSYRAAVRLAGGKPVPVPLDEENGFLPDpEALEAAITP-RTKAIV 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 187 YSNPNNPSWICLKDEELKIIGELATQYDVIVLEDLAYFAMDFrqdlsTPYHAPYQPSVAHYTDNYILLISGSKAFSYAGQ 266
Cdd:COG0436  169 LNSPNNPTGAVYSREELEALAELAREHDLLVISDEIYEELVY-----DGAEHVSILSLPGLKDRTIVINSFSKSYAMTGW 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 267 RIGVSCISDKLYHRhypgfdkrygggtfgtvfIHRVLYALSSGTSHSAQFAMAAMLKAANEgkynFLNEVR-IYGERARK 345
Cdd:COG0436  244 RIGYAVGPPELIAA------------------LLKLQSNLTSCAPTPAQYAAAAALEGPQD----YVEEMRaEYRRRRDL 301

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 346 LKEIFLRYGFHLVYdkdledPVAdGFYFTIGYP--GMTSGELAKELMY-YGVSAISLVTTGSQQQG-LRACTSfIKEHQY 421
Cdd:COG0436  302 LVEGLNEIGLSVVK------PEG-AFYLFADVPelGLDSEEFAERLLEeAGVAVVPGSAFGPAGEGyVRISYA-TSEERL 373

                        410
                 ....*....|....
gi 492291028 422 AQLDERMKLFAENH 435
Cdd:COG0436  374 EEALERLARFLERY 387
 
Name Accession Description Interval E-value
AspB COG0436
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ...
 28-435 9.06e-44

Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis


Pssm-ID: 440205 [Multi-domain]  Cd Length: 387  Bit Score: 157.60  E-value: 9.06e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  28 IREVKAIAAKAEtASGVEFIKMEMGVPGLPPSTVGVKAEIEALQNGiASLYPDINGLPELKSEASKFIKAFIDIDLKPEG 107
Cdd:COG0436   15 IREVSALAAELK-AAGEDVIDLGIGEPDFPTPDHIREAAIEALDDG-VTGYTPSAGIPELREAIAAYYKRRYGVDLDPDE 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 108 CVPVTGSMQGTFASFLTCsqCDEKkDTILFIDPGFPVQKQQLVVMGQKYETFDVYDYRGDKLK-EKLESYLKKgNISAVI 186
Cdd:COG0436   93 ILVTNGAKEALALALLAL--LNPG-DEVLVPDPGYPSYRAAVRLAGGKPVPVPLDEENGFLPDpEALEAAITP-RTKAIV 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 187 YSNPNNPSWICLKDEELKIIGELATQYDVIVLEDLAYFAMDFrqdlsTPYHAPYQPSVAHYTDNYILLISGSKAFSYAGQ 266
Cdd:COG0436  169 LNSPNNPTGAVYSREELEALAELAREHDLLVISDEIYEELVY-----DGAEHVSILSLPGLKDRTIVINSFSKSYAMTGW 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 267 RIGVSCISDKLYHRhypgfdkrygggtfgtvfIHRVLYALSSGTSHSAQFAMAAMLKAANEgkynFLNEVR-IYGERARK 345
Cdd:COG0436  244 RIGYAVGPPELIAA------------------LLKLQSNLTSCAPTPAQYAAAAALEGPQD----YVEEMRaEYRRRRDL 301

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 346 LKEIFLRYGFHLVYdkdledPVAdGFYFTIGYP--GMTSGELAKELMY-YGVSAISLVTTGSQQQG-LRACTSfIKEHQY 421
Cdd:COG0436  302 LVEGLNEIGLSVVK------PEG-AFYLFADVPelGLDSEEFAERLLEeAGVAVVPGSAFGPAGEGyVRISYA-TSEERL 373

                        410
                 ....*....|....
gi 492291028 422 AQLDERMKLFAENH 435
Cdd:COG0436  374 EEALERLARFLERY 387
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
 47-433 5.81e-38

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 140.94  E-value: 5.81e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  47 IKMEMGVPGLPPSTVGVKAEIEALQNGIASLYPDINGLPELKSEASKFIKAFIDIDLKPEGCVPVTGSMQGTFASFLTCS 126
Cdd:cd00609    1 IDLSIGEPDFPPPPEVLEALAAAALRAGLLGYYPDPGLPELREAIAEWLGRRGGVDVPPEEIVVTNGAQEALSLLLRALL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 127 qcdEKKDTILFIDPGFPVQKQQLVVMGQKYETFDVYDYRGDKLKEKLESYLKKGNISAVIYSNPNNPSWICLKDEELKII 206
Cdd:cd00609   81 ---NPGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDEEGGFLLDLELLEAAKTPKTKLLYLNNPNNPTGAVLSEEELEEL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 207 GELATQYDVIVLEDLAYfamdfrQDLSTPYHAPYQPSVAHYTDNYILLISGSKAFSYAGQRIGVSCISDKLYHRhypgfd 286
Cdd:cd00609  158 AELAKKHGILIISDEAY------AELVYDGEPPPALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPEELLE------ 225

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 287 krygggtfgtvFIHRVLYALSSGTSHSAQFAMAAMLKaaneGKYNFLNEVR-IYGERARKLKEIFLRYGFHLVYDKDled 365
Cdd:cd00609  226 -----------RLKKLLPYTTSGPSTLSQAAAAAALD----DGEEHLEELReRYRRRRDALLEALKELGPLVVVKPS--- 287

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 366 pvaDGFYFTIGYPGMTSGELAKELMY-YGVSAISLVTTGSQQQG-LRACTSFIKEhqyaQLDERMKLFAE 433
Cdd:cd00609  288 ---GGFFLWLDLPEGDDEEFLERLLLeAGVVVRPGSAFGEGGEGfVRLSFATPEE----ELEEALERLAE 350
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
52-389 8.43e-22

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 95.84  E-value: 8.43e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028   52 GVPGLPPSTVGVKAEIEALQNGIASLYPDINGLPELKSEASKFIKAFIDIDLKPEGCVpVTGSmqGTFASFLTCSQC-DE 130
Cdd:pfam00155   9 NEYLGDTLPAVAKAEKDALAGGTRNLYGPTDGHPELREALAKFLGRSPVLKLDREAAV-VFGS--GAGANIEALIFLlAN 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  131 KKDTILFIDPGFPVQKQQLVVMG---QKYETFDVYDYRGDklKEKLESYLKKGNIsAVIYSNPNNPSWICLKDEELKIIG 207
Cdd:pfam00155  86 PGDAILVPAPTYASYIRIARLAGgevVRYPLYDSNDFHLD--FDALEAALKEKPK-VVLHTSPHNPTGTVATLEELEKLL 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  208 ELATQYDVIVLEDLAYFAMDFrqdlSTPYHAPYQPSVAHYtDNYILLISGSKAFSYAGQRIGVSCISDKLYHRhypgfdk 287
Cdd:pfam00155 163 DLAKEHNILLLVDEAYAGFVF----GSPDAVATRALLAEG-PNLLVVGSFSKAFGLAGWRVGYILGNAAVISQ------- 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  288 rygggtfgtvfihrvLYALSSG--TSHSAQFAMAAMLKAANEGKYNFLNEVRIYGERARKLKEIFLRYGFhlvydkDLED 365
Cdd:pfam00155 231 ---------------LRKLARPfySSTHLQAAAAAALSDPLLVASELEEMRQRIKERRDYLRDGLQAAGL------SVLP 289

                         330       340
                  ....*....|....*....|....
gi 492291028  366 PVAdGFYFTIGYPGMTSGELAKEL 389
Cdd:pfam00155 290 SQA-GFFLLTGLDPETAKELAQVL 312
PRK06348 PRK06348
pyridoxal phosphate-dependent aminotransferase;
33-269 1.37e-17

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180537  Cd Length: 384  Bit Score: 84.00  E-value: 1.37e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  33 AIAAKAETASGVefIKMEMGVPGLPPSTVGVKAEIEALQNGiASLYPDINGLPELKSEASKFIKAFIDIDLKPEGCVPVT 112
Cdd:PRK06348  20 EIATLAKKFPDI--IDLSLGDPDLITDESIINAAFEDAKKG-HTRYTDSGGDVELIEEIIKYYSKNYDLSFKRNEIMATV 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 113 GSMQGTFasfLTCSQCDEKKDTILFIDPGFPVQKQQLVVMGQKYETFDVYDYRG-----DKLKEKLESYLKkgnisAVIY 187
Cdd:PRK06348  97 GACHGMY---LALQSILDPGDEVIIHEPYFTPYKDQIEMVGGKPIILETYEEDGfqinvKKLEALITSKTK-----AIIL 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 188 SNPNNPSWICLKDEELKIIGELATQYDVIVLEDLAYFAMDFRQDLsTPYhapyqPSVAHYTDNYILLISGSKAFSYAGQR 267
Cdd:PRK06348 169 NSPNNPTGAVFSKETLEEIAKIAIEYDLFIISDEVYDGFSFYEDF-VPM-----ATLAGMPERTITFGSFSKDFAMTGWR 242


                 ..
gi 492291028 268 IG 269
Cdd:PRK06348 243 IG 244
hisC TIGR01141
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; ...
 28-269 1.63e-10

histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; imidazole acetol-phosphate transaminase Histidinol-phosphate aminotransferase is a pyridoxal-phosphate dependent enzyme. [Amino acid biosynthesis, Histidine family]


Pssm-ID: 273467  Cd Length: 350  Bit Score: 62.29  E-value: 1.63e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028   28 IREVKAIAAKAETASGVEFIK---MEMGVPGLPPSTVGVKAEIEALQngiasLYPDINGlPELKSEASKFIkafidiDLK 104
Cdd:TIGR01141   4 IKNLSPYQPGARELGGDEVIKlnsNENPFGPPEKAKEALRAELKKLH-----RYPDPDP-AELKQALADYY------GVD 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  105 PEGCVPVTGSMQGTfaSFLTCSQCDEKkDTILFIDPGFPVQKQQLVVMGQKYETfdvYDYRGD-KLKEKLESYLKKGNIS 183
Cdd:TIGR01141  72 PEQILLGNGSDEII--DLLIRAFLEPG-DAVLVPPPTYSMYEISAKIHGAEVVK---VPLDEDgQLDLEDILVAIDDKPK 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  184 AVIYSNPNNPSWICLKDEELKIIGElATQYDVIVLEDLAYFamDFRQDLST-PYHAPYqpsvahytDNYILLISGSKAFS 262
Cdd:TIGR01141 146 LVFLCSPNNPTGNLFSRGDIEAVLE-RTPGDALVVVDEAYG--EFSGEPSTlPLLAEY--------PNLIVLRTLSKAFG 214


                  ....*..
gi 492291028  263 YAGQRIG 269
Cdd:TIGR01141 215 LAGLRIG 221
 
Name Accession Description Interval E-value
AspB COG0436
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ...
 28-435 9.06e-44

Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis


Pssm-ID: 440205 [Multi-domain]  Cd Length: 387  Bit Score: 157.60  E-value: 9.06e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  28 IREVKAIAAKAEtASGVEFIKMEMGVPGLPPSTVGVKAEIEALQNGiASLYPDINGLPELKSEASKFIKAFIDIDLKPEG 107
Cdd:COG0436   15 IREVSALAAELK-AAGEDVIDLGIGEPDFPTPDHIREAAIEALDDG-VTGYTPSAGIPELREAIAAYYKRRYGVDLDPDE 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 108 CVPVTGSMQGTFASFLTCsqCDEKkDTILFIDPGFPVQKQQLVVMGQKYETFDVYDYRGDKLK-EKLESYLKKgNISAVI 186
Cdd:COG0436   93 ILVTNGAKEALALALLAL--LNPG-DEVLVPDPGYPSYRAAVRLAGGKPVPVPLDEENGFLPDpEALEAAITP-RTKAIV 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 187 YSNPNNPSWICLKDEELKIIGELATQYDVIVLEDLAYFAMDFrqdlsTPYHAPYQPSVAHYTDNYILLISGSKAFSYAGQ 266
Cdd:COG0436  169 LNSPNNPTGAVYSREELEALAELAREHDLLVISDEIYEELVY-----DGAEHVSILSLPGLKDRTIVINSFSKSYAMTGW 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 267 RIGVSCISDKLYHRhypgfdkrygggtfgtvfIHRVLYALSSGTSHSAQFAMAAMLKAANEgkynFLNEVR-IYGERARK 345
Cdd:COG0436  244 RIGYAVGPPELIAA------------------LLKLQSNLTSCAPTPAQYAAAAALEGPQD----YVEEMRaEYRRRRDL 301

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 346 LKEIFLRYGFHLVYdkdledPVAdGFYFTIGYP--GMTSGELAKELMY-YGVSAISLVTTGSQQQG-LRACTSfIKEHQY 421
Cdd:COG0436  302 LVEGLNEIGLSVVK------PEG-AFYLFADVPelGLDSEEFAERLLEeAGVAVVPGSAFGPAGEGyVRISYA-TSEERL 373

                        410
                 ....*....|....
gi 492291028 422 AQLDERMKLFAENH 435
Cdd:COG0436  374 EEALERLARFLERY 387
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
 47-433 5.81e-38

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 140.94  E-value: 5.81e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  47 IKMEMGVPGLPPSTVGVKAEIEALQNGIASLYPDINGLPELKSEASKFIKAFIDIDLKPEGCVPVTGSMQGTFASFLTCS 126
Cdd:cd00609    1 IDLSIGEPDFPPPPEVLEALAAAALRAGLLGYYPDPGLPELREAIAEWLGRRGGVDVPPEEIVVTNGAQEALSLLLRALL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 127 qcdEKKDTILFIDPGFPVQKQQLVVMGQKYETFDVYDYRGDKLKEKLESYLKKGNISAVIYSNPNNPSWICLKDEELKII 206
Cdd:cd00609   81 ---NPGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDEEGGFLLDLELLEAAKTPKTKLLYLNNPNNPTGAVLSEEELEEL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 207 GELATQYDVIVLEDLAYfamdfrQDLSTPYHAPYQPSVAHYTDNYILLISGSKAFSYAGQRIGVSCISDKLYHRhypgfd 286
Cdd:cd00609  158 AELAKKHGILIISDEAY------AELVYDGEPPPALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPEELLE------ 225

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 287 krygggtfgtvFIHRVLYALSSGTSHSAQFAMAAMLKaaneGKYNFLNEVR-IYGERARKLKEIFLRYGFHLVYDKDled 365
Cdd:cd00609  226 -----------RLKKLLPYTTSGPSTLSQAAAAAALD----DGEEHLEELReRYRRRRDALLEALKELGPLVVVKPS--- 287

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 366 pvaDGFYFTIGYPGMTSGELAKELMY-YGVSAISLVTTGSQQQG-LRACTSFIKEhqyaQLDERMKLFAE 433
Cdd:cd00609  288 ---GGFFLWLDLPEGDDEEFLERLLLeAGVVVRPGSAFGEGGEGfVRLSFATPEE----ELEEALERLAE 350
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
52-389 8.43e-22

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 95.84  E-value: 8.43e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028   52 GVPGLPPSTVGVKAEIEALQNGIASLYPDINGLPELKSEASKFIKAFIDIDLKPEGCVpVTGSmqGTFASFLTCSQC-DE 130
Cdd:pfam00155   9 NEYLGDTLPAVAKAEKDALAGGTRNLYGPTDGHPELREALAKFLGRSPVLKLDREAAV-VFGS--GAGANIEALIFLlAN 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  131 KKDTILFIDPGFPVQKQQLVVMG---QKYETFDVYDYRGDklKEKLESYLKKGNIsAVIYSNPNNPSWICLKDEELKIIG 207
Cdd:pfam00155  86 PGDAILVPAPTYASYIRIARLAGgevVRYPLYDSNDFHLD--FDALEAALKEKPK-VVLHTSPHNPTGTVATLEELEKLL 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  208 ELATQYDVIVLEDLAYFAMDFrqdlSTPYHAPYQPSVAHYtDNYILLISGSKAFSYAGQRIGVSCISDKLYHRhypgfdk 287
Cdd:pfam00155 163 DLAKEHNILLLVDEAYAGFVF----GSPDAVATRALLAEG-PNLLVVGSFSKAFGLAGWRVGYILGNAAVISQ------- 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  288 rygggtfgtvfihrvLYALSSG--TSHSAQFAMAAMLKAANEGKYNFLNEVRIYGERARKLKEIFLRYGFhlvydkDLED 365
Cdd:pfam00155 231 ---------------LRKLARPfySSTHLQAAAAAALSDPLLVASELEEMRQRIKERRDYLRDGLQAAGL------SVLP 289

                         330       340
                  ....*....|....*....|....
gi 492291028  366 PVAdGFYFTIGYPGMTSGELAKEL 389
Cdd:pfam00155 290 SQA-GFFLLTGLDPETAKELAQVL 312
PRK06348 PRK06348
pyridoxal phosphate-dependent aminotransferase;
33-269 1.37e-17

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180537  Cd Length: 384  Bit Score: 84.00  E-value: 1.37e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  33 AIAAKAETASGVefIKMEMGVPGLPPSTVGVKAEIEALQNGiASLYPDINGLPELKSEASKFIKAFIDIDLKPEGCVPVT 112
Cdd:PRK06348  20 EIATLAKKFPDI--IDLSLGDPDLITDESIINAAFEDAKKG-HTRYTDSGGDVELIEEIIKYYSKNYDLSFKRNEIMATV 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 113 GSMQGTFasfLTCSQCDEKKDTILFIDPGFPVQKQQLVVMGQKYETFDVYDYRG-----DKLKEKLESYLKkgnisAVIY 187
Cdd:PRK06348  97 GACHGMY---LALQSILDPGDEVIIHEPYFTPYKDQIEMVGGKPIILETYEEDGfqinvKKLEALITSKTK-----AIIL 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 188 SNPNNPSWICLKDEELKIIGELATQYDVIVLEDLAYFAMDFRQDLsTPYhapyqPSVAHYTDNYILLISGSKAFSYAGQR 267
Cdd:PRK06348 169 NSPNNPTGAVFSKETLEEIAKIAIEYDLFIISDEVYDGFSFYEDF-VPM-----ATLAGMPERTITFGSFSKDFAMTGWR 242


                 ..
gi 492291028 268 IG 269
Cdd:PRK06348 243 IG 244
PRK08361 PRK08361
aspartate aminotransferase; Provisional
 25-269 1.26e-13

aspartate aminotransferase; Provisional


Pssm-ID: 236248 [Multi-domain]  Cd Length: 391  Bit Score: 72.22  E-value: 1.26e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  25 KATIREVKAIAAKAEtasgvEFIKMEMGVPGLPPSTVGVKAEIEALQNGIASLYPDInGLPELKSEASKFIKAFIDIDLK 104
Cdd:PRK08361  19 RSKIRELFERASKME-----NVISLGIGEPDFDTPKNIKEAAKRALDEGWTHYTPNA-GIPELREAIAEYYKKFYGVDVD 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 105 PEGCVPVTGSMQGTFASFLTCSqcdEKKDTILFIDPGFPVQKQQLVVMGQKYETFDVY---DYRGDKlKEKLESYLKKGN 181
Cdd:PRK08361  93 VDNVIVTAGAYEATYLAFESLL---EEGDEVIIPDPAFVCYVEDAKIAEAKPIRIPLReenEFQPDP-DELLELITKRTR 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 182 ISAVIYsnPNNPSWICLKDEELKIIGELATQYDVIVLEDLAY--FAMDfrqdlstpyHAPYQPSVAHYTDNYILLISGSK 259
Cdd:PRK08361 169 MIVINY--PNNPTGATLDKEVAKAIADIAEDYNIYILSDEPYehFLYE---------GAKHYPMIKYAPDNTILANSFSK 237

                        250
                 ....*....|
gi 492291028 260 AFSYAGQRIG 269
Cdd:PRK08361 238 TFAMTGWRLG 247
PRK08363 PRK08363
alanine aminotransferase; Validated
 28-275 2.16e-13

alanine aminotransferase; Validated


Pssm-ID: 181402  Cd Length: 398  Bit Score: 71.38  E-value: 2.16e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  28 IREVKAIAAKAETaSGVEFIKMEMGVPG----LPPSTVgVKAEIEALQNGiASLYPDINGLPELKSEASKFIKAFIDIDL 103
Cdd:PRK08363  15 IRDVVLPARELEK-KGIKVIRLNIGDPVkfdfQPPEHM-KEAYCRAIKEG-HNYYGPSEGLPELREAIVKREKRKNGVDI 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 104 KPEGCV---PVTGSMQGTFASFLtcsqcdEKKDTILFIDPGFPVQKQQLVVMGQK---YETFDVYDYRGD--KLKEKLES 175
Cdd:PRK08363  92 TPDDVRvtaAVTEALQLIFGALL------DPGDEILIPGPSYPPYTGLVKFYGGVpveYRTIEEEGWQPDidDIRKKITE 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 176 YLKkgnisAVIYSNPNNPSWICLKDEELKIIGELATQYDVIVLEDLAYFAMDFRQDLSTPyhapyqPSVAHyTDNYILLI 255
Cdd:PRK08363 166 KTK-----AIAVINPNNPTGALYEKKTLKEILDIAGEHDLPVISDEIYDLMTYEGKHVSP------GSLTK-DVPVIVMN 233

                        250       260
                 ....*....|....*....|
gi 492291028 256 SGSKAFSYAGQRIGVSCISD 275
Cdd:PRK08363 234 GLSKVYFATGWRLGYIYFVD 253
PRK07309 PRK07309
pyridoxal phosphate-dependent aminotransferase;
30-269 1.37e-12

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235985  Cd Length: 391  Bit Score: 68.98  E-value: 1.37e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  30 EVKAIAAKAETASGVE-FIKMEMGVPGL-PPSTVGvKAEIEALQNGiASLYPDINGLPELKSEASKFIKAFIDIDLKPEG 107
Cdd:PRK07309  15 EVSLIRQFDQSISDIPgILKLTLGEPDFtTPDHVK-EAAKRAIDAN-QSHYTGMAGLLELRQAAADFVKEKYNLDYAPEN 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 108 CVPVT-GSMQGTFASFLTCSqcdEKKDTILFIDPGFPVQKQQLVVMGQKYETFDVYDYRGDKLKEKLESYLK--KGNISA 184
Cdd:PRK07309  93 EILVTiGATEALSASLTAIL---EPGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENDFVLTPEMLEKAILeqGDKLKA 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 185 VIYSNPNNPSWICLKDEELKIIGELATQYDVIVLEDLAYFAMDFRQDLSTpyhapyqpSVAHYTDNYILLISG-SKAFSY 263
Cdd:PRK07309 170 VILNYPANPTGVTYSREQIKALADVLKKYDIFVISDEVYSELTYTGEPHV--------SIAEYLPDQTILINGlSKSHAM 241


                 ....*.
gi 492291028 264 AGQRIG 269
Cdd:PRK07309 242 TGWRIG 247
PRK08175 PRK08175
aminotransferase; Validated
 27-279 1.53e-10

aminotransferase; Validated


Pssm-ID: 181268 [Multi-domain]  Cd Length: 395  Bit Score: 62.42  E-value: 1.53e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  27 TIREVKAiaakAETASGVEFIKMEMGVPGLPPSTVGVKAEIEALQNGIASLYPDINGLPELKSEASKFIKAFIDIDLKPE 106
Cdd:PRK08175  16 ITAELKM----AARRRGEDIIDFSMGNPDGPTPPHIVEKLCEVAQRPDTHGYSTSRGIPRLRRAISRWYQDRYDVDIDPE 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 107 GCVPVT-GSMQGTFASFLTCSqcdEKKDTILFIDPGFPVQKQQLVVMGQKYETFDVY---DYRGDKLKEKLESYLKKgni 182
Cdd:PRK08175  92 SEAIVTiGSKEGLAHLMLATL---DHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVegvDFFNELERAIRESYPKP--- 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 183 SAVIYSNPNNPSWICLKDEELKIIGELATQYDVIVLEDLAYFAMDFrqdlsTPYHAPYQPSVAHYTDNYILLISGSKAFS 262
Cdd:PRK08175 166 KMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVY-----DGWKAPSIMQVPGAKDVAVEFFTLSKSYN 240

                        250
                 ....*....|....*..
gi 492291028 263 YAGQRIGVSCISDKLYH 279
Cdd:PRK08175 241 MAGWRIGFMVGNPELVS 257
hisC TIGR01141
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; ...
 28-269 1.63e-10

histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; imidazole acetol-phosphate transaminase Histidinol-phosphate aminotransferase is a pyridoxal-phosphate dependent enzyme. [Amino acid biosynthesis, Histidine family]


Pssm-ID: 273467  Cd Length: 350  Bit Score: 62.29  E-value: 1.63e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028   28 IREVKAIAAKAETASGVEFIK---MEMGVPGLPPSTVGVKAEIEALQngiasLYPDINGlPELKSEASKFIkafidiDLK 104
Cdd:TIGR01141   4 IKNLSPYQPGARELGGDEVIKlnsNENPFGPPEKAKEALRAELKKLH-----RYPDPDP-AELKQALADYY------GVD 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  105 PEGCVPVTGSMQGTfaSFLTCSQCDEKkDTILFIDPGFPVQKQQLVVMGQKYETfdvYDYRGD-KLKEKLESYLKKGNIS 183
Cdd:TIGR01141  72 PEQILLGNGSDEII--DLLIRAFLEPG-DAVLVPPPTYSMYEISAKIHGAEVVK---VPLDEDgQLDLEDILVAIDDKPK 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  184 AVIYSNPNNPSWICLKDEELKIIGElATQYDVIVLEDLAYFamDFRQDLST-PYHAPYqpsvahytDNYILLISGSKAFS 262
Cdd:TIGR01141 146 LVFLCSPNNPTGNLFSRGDIEAVLE-RTPGDALVVVDEAYG--EFSGEPSTlPLLAEY--------PNLIVLRTLSKAFG 214


                  ....*..
gi 492291028  263 YAGQRIG 269
Cdd:TIGR01141 215 LAGLRIG 221
ARO8 COG1167
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ...
 78-423 3.99e-10

DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis


Pssm-ID: 440781 [Multi-domain]  Cd Length: 471  Bit Score: 61.38  E-value: 3.99e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  78 YPDINGLPELKSEASKFIKAFiDIDLKPEGCVPVTGSMQgtfASFLTCSQCDEKKDTILFIDPGFPVQKQQLVVMGQKYE 157
Cdd:COG1167  144 YGDPQGLPELREAIARYLARR-GVPASPDQILITSGAQQ---ALDLALRALLRPGDTVAVESPTYPGALAALRAAGLRLV 219

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 158 TFDVyDYRGDKLkEKLESYLKKGNISAViYSNPN--NPSWICLKDEELKIIGELATQYDVIVLEDlAYFAmDFRqdlstp 235
Cdd:COG1167  220 PVPV-DEDGLDL-DALEAALRRHRPRAV-YVTPShqNPTGATMSLERRRALLELARRHGVPIIED-DYDS-ELR------ 288

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 236 YHAPYQPSVAHY-TDNYILLISG-SKAFSyAGQRIGVSCISDKLYHRhypgfdkrygggtfgtvfIHRVLYALSSGTSHS 313
Cdd:COG1167  289 YDGRPPPPLAALdAPGRVIYIGSfSKTLA-PGLRLGYLVAPGRLIER------------------LARLKRATDLGTSPL 349

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 314 AQFAMAAMLKaanEGKY-NFLNEVR-IYGERARKLKEIFLRYGFHLVydkDLEDPVAdGFYFTIGYP-GMTSGELAKELM 390
Cdd:COG1167  350 TQLALAEFLE---SGHYdRHLRRLRrEYRARRDLLLAALARHLPDGL---RVTGPPG-GLHLWLELPeGVDAEALAAAAL 422

                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 492291028 391 YYGVSAISL---VTTGSQQQGLRACTSFIKEHQYAQ 423
Cdd:COG1167  423 ARGILVAPGsafSADGPPRNGLRLGFGAPSEEELEE 458
HisC COG0079
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ...
 55-269 5.43e-10

Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 439849 [Multi-domain]  Cd Length: 341  Bit Score: 60.53  E-value: 5.43e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  55 GLPPStvgVKAEIEALQNGIAsLYPDINGlPELKSEASKFIkafidiDLKPEGCVPVTGS---MQGTFASFLtcsqcdEK 131
Cdd:COG0079   26 GPPPK---VLEAIAAALDALN-RYPDPDA-TALREALAEYY------GVPPEQVLVGNGSdelIQLLARAFL------GP 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 132 KDTILFIDPGFPVQKQQLVVMGQKYETFDVY-DYRGDklkekLESYLK--KGNISAVIYSNPNNPSWICLKDEEL-KIIG 207
Cdd:COG0079   89 GDEVLVPEPTFSEYPIAARAAGAEVVEVPLDeDFSLD-----LDALLAaiTERTDLVFLCNPNNPTGTLLPREELeALLE 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492291028 208 ELATqyDVIVLEDLAYfaMDFrqdlstpyhAPYQPSVAHYTDNY---ILLISGSKAFSYAGQRIG 269
Cdd:COG0079  164 ALPA--DGLVVVDEAY--AEF---------VPEEDSALPLLARYpnlVVLRTFSKAYGLAGLRLG 215
PRK07683 PRK07683
aminotransferase A; Validated
 9-269 2.15e-09

aminotransferase A; Validated


Pssm-ID: 236075  Cd Length: 387  Bit Score: 58.97  E-value: 2.15e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028   9 HLIDETIEEFQITDfskatIREVKAIAAKAETAsgvefIKMEMGVPGLP-PSTVGVkAEIEALQNGIASlYPDINGLPEL 87
Cdd:PRK07683   3 HLINPRVKDIQISG-----IRQFSNMVQNYDNL-----ISLTIGQPDFPtPSHVKE-AAKRAITENYTS-YTHNAGLLEL 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  88 KSEASKFIKAFIDIDLKPEGCVPVT-GSMQGTFASFLTCSqcdEKKDTILFIDPGFPVQKQQLVVMGQKYETFDVYDYrG 166
Cdd:PRK07683  71 RKAACNFVKDKYDLHYSPESEIIVTiGASEAIDIAFRTIL---EPGTEVILPAPIYPGYEPIIRLCGAKPVFIDTRST-G 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 167 DKL-KEKLESYLKKgNISAVIYSNPNNPSWICLKDEELKIIGELATQYDVIVLEDLAYFAMDFRQdlstPYHapyqpSVA 245
Cdd:PRK07683 147 FRLtAEALENAITE-KTRCVVLPYPSNPTGVTLSKEELQDIADVLKDKNIFVLSDEIYSELVYEQ----PHT-----SIA 216

                        250       260
                 ....*....|....*....|....*..
gi 492291028 246 HYTD--NYILLISG-SKAFSYAGQRIG 269
Cdd:PRK07683 217 HFPEmrEKTIVINGlSKSHSMTGWRIG 243
PRK06225 PRK06225
pyridoxal phosphate-dependent aminotransferase;
64-269 2.33e-09

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235749 [Multi-domain]  Cd Length: 380  Bit Score: 59.00  E-value: 2.33e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  64 KAEIEALQNGIASLYPDINGLPELKSEASKfikafiDIDLKPEGCVPVTGsmqGTFASFLTCSQCDEKKDTILFIDPGFP 143
Cdd:PRK06225  48 EAMIRCIEEGEYCKYPPPEGFPELRELILK------DLGLDDDEALITAG---ATESLYLVMRAFLSPGDNAVTPDPGYL 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 144 VQKQQLVVMGQKYETFDVY----DYR--GDKLKEKLEsylkkGNISAVIYSNPNNPSWICLKDEELKIIGELATQYDVIV 217
Cdd:PRK06225 119 IIDNFASRFGAEVIEVPIYseecNYKltPELVKENMD-----ENTRLIYLIDPLNPLGSSYTEEEIKEFAEIARDNDAFL 193

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 492291028 218 LEDLAYfaMDFrqdlstpyhAPYQPSVAHYT-DNYILLISGSKAFSYAGQRIG 269
Cdd:PRK06225 194 LHDCTY--RDF---------AREHTLAAEYApEHTVTSYSFSKIFGMAGLRIG 235
PRK05764 PRK05764
aspartate aminotransferase; Provisional
 33-389 2.41e-09

aspartate aminotransferase; Provisional


Pssm-ID: 235596  Cd Length: 393  Bit Score: 58.98  E-value: 2.41e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  33 AIAAKAET--ASGVEFIKMEMGVPGLP-PSTVgVKAEIEALQNGIASlYPDINGLPELKSE-ASKFiKAFIDIDLKPEGC 108
Cdd:PRK05764  18 AVTAKAKElkAQGRDVISLGAGEPDFDtPEHI-KEAAIEALDDGKTK-YTPAAGIPELREAiAAKL-KRDNGLDYDPSQV 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 109 VPVTGSMQGTFASFLTCsqCDEKkDTILFIDPGFPVQKQQL------VVMGQKYETFDvYDYRGDKLKEKLESYLKkgni 182
Cdd:PRK05764  95 IVTTGAKQALYNAFMAL--LDPG-DEVIIPAPYWVSYPEMVklaggvPVFVPTGEENG-FKLTVEQLEAAITPKTK---- 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 183 sAVIYSNPNNPSWICLKDEELKIIGELATQYDVIVLEDLAYfamdfrQDLStpYHAPYQPSVAHYTD---NYILLISG-S 258
Cdd:PRK05764 167 -ALILNSPSNPTGAVYSPEELEAIADVAVEHDIWVLSDEIY------EKLV--YDGAEFTSIASLSPelrDRTITVNGfS 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 259 KAFSYAGQRIGvscisdklyhrhypgfdkrYGGGTfgtvfiHRVLYALSSGTSHS----AQFAMAAMLkAANEGKYNFLN 334
Cdd:PRK05764 238 KAYAMTGWRLG-------------------YAAGP------KELIKAMSKLQSHStsnpTSIAQYAAV-AALNGPQDEVE 291

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492291028 335 E-VRIYGERAR----KLKEIflrygfhlvydKDLEDPVADG-FYF------TIGYPGMTSGELAKEL 389
Cdd:PRK05764 292 EmRQAFEERRDlmvdGLNEI-----------PGLECPKPEGaFYVfpnvskLLGKSITDSLEFAEAL 347
PRK09276 PRK09276
LL-diaminopimelate aminotransferase; Provisional
 26-272 4.87e-09

LL-diaminopimelate aminotransferase; Provisional


Pssm-ID: 181749  Cd Length: 385  Bit Score: 58.00  E-value: 4.87e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  26 ATIREVKAIAAkaetASGVEFIKMEMGVPGLPPSTVGVKAEIEALQNGIASLYPDINGLPELKSEASKFIKAFIDIDLKP 105
Cdd:PRK09276  17 AEIDKKKAEKI----ARGVDVISLGIGDPDLPTPDHIIEAMCKAVEDPENHQYPSYEGMLEFRKAVADWYKRRFGVELDP 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 106 EG-CVPVTGSMQG---TFASFLtcsqcdEKKDTILFIDPGFPVQKQQLVVMGQkyETFDVYDYRGDKLKEKLESY----L 177
Cdd:PRK09276  93 ETeVISLIGSKEGiahIPLAFV------NPGDVVLVPDPGYPVYKIGTIFAGG--EPYFMPLKEENGFLPDLDAIpedvA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 178 KKGNISAVIYsnPNNPSWICLKDEELKIIGELATQYDVIVLEDLAYFAMDFRQdlstpYHAPYQPSVAHYTDNYILLISG 257
Cdd:PRK09276 165 KKAKLMFINY--PNNPTGAVADLEFFEEVVDFAKKYDIIVCHDAAYSEIAYDG-----YKPPSFLEVPGAKDVGIEFHSL 237

                        250
                 ....*....|....*
gi 492291028 258 SKAFSYAGQRIGVSC 272
Cdd:PRK09276 238 SKTYNMTGWRIGFAV 252
PRK06207 PRK06207
pyridoxal phosphate-dependent aminotransferase;
67-271 5.92e-09

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235742  Cd Length: 405  Bit Score: 57.47  E-value: 5.92e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  67 IEALQNGIASLYPDINGLPELKSEASKFIKAFIDIDLKPEGCVPVTGSMQGtfASFLTCSQCDEKKDTILFIDPGFPVQK 146
Cdd:PRK06207  63 SAGVERGGVQAYTEYRGDADIRELLAARLAAFTGAPVDAADELIITPGTQG--ALFLAVAATVARGDKVAIVQPDYFANR 140

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 147 Q-------QLVVMGQKYETFDvyDYRGDKLKEkLESYLKKGnISAVIYSNPNNPSWICLKDEELKIIGELATQYDVIVLE 219
Cdd:PRK06207 141 KlveffegEMVPVQLDYLSAD--KRAGLDLDQ-LEEAFKAG-VRVFLFSNPNNPAGVVYSAEEIAQIAALARRYGATVIV 216

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 492291028 220 DLAYFAMDFrqDLSTPYHAPYQPSVAhytDNYILLISGSKAFSYAGQRIGVS 271
Cdd:PRK06207 217 DQLYSRLLY--DGTSYTHLRALPIDP---ENVITIMGPSKTESLSGYRLGVA 263
PRK07681 PRK07681
LL-diaminopimelate aminotransferase;
18-390 4.97e-08

LL-diaminopimelate aminotransferase;


Pssm-ID: 181081  Cd Length: 399  Bit Score: 54.81  E-value: 4.97e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  18 FQITDFSKATIREVKAIAAkaetasGVEFIKMEMGVPGLPPSTVGVKAEIEALQNGIASLYPdINGLPELKSEASKFIKA 97
Cdd:PRK07681  12 FQSSIFSELGAYKKEKIAA------GHKMIDLSIGNPDMPPADFVREEMVHTANQKESYGYT-LSGIQEFHEAVTEYYNN 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  98 FIDIDLKPEGCV-PVTGSMQGTfaSFLTCSQCDEKkDTILFIDPGFPVQKQQLVVMGQKYETFDVY---DYRGDkLKEKL 173
Cdd:PRK07681  85 THNVILNADKEVlLLMGSQDGL--VHLPMVYANPG-DIILVPDPGYTAYETGIQMAGATSYYMPLKkenDFLPD-LELIP 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 174 ESYLKKGNIsaVIYSNPNNPSWICLKDEELKIIGELATQYDVIVLEDLAY--FAMDFRQDLSTPyhapyqpSVAHYTDNY 251
Cdd:PRK07681 161 EEIADKAKM--MILNFPGNPVPAMAHEDFFKEVIAFAKKHNIIVVHDFAYaeFYFDGNKPISFL-------SVPGAKEVG 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 252 ILLISGSKAFSYAGQRIGVSCisdklyhrhypgfdkrygggtfGTVFIHRVLYALSSGTSHSA----QFAMAAMLKAANE 327
Cdd:PRK07681 232 VEINSLSKSYSLAGSRIGYMI----------------------GNEEIVRALTQFKSNTDYGVflpiQKAACAALRNGAA 289

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492291028 328 gkynFLNEVR-IYGERARKLKEIFLRYGFhlvydkDLEDPVADGFYFTIGYPGMTSGELAKELM 390
Cdd:PRK07681 290 ----FCEKNRgIYQERRDTLVDGFRTFGW------NVDKPAGSMFVWAEIPKGWTSLSFAYALM 343
PRK07568 PRK07568
pyridoxal phosphate-dependent aminotransferase;
28-270 6.32e-08

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181036  Cd Length: 397  Bit Score: 54.47  E-value: 6.32e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  28 IREVKAIAAKAEtASGVEFIKMEMGVPGLPPSTVGVKAeIEALQNGIASlYPDINGLPELKSEASKFIKAFiDIDLKPEG 107
Cdd:PRK07568  15 IRKLVPYADEAK-KRGIKVYHLNIGQPDIKTPEVFFEA-IKNYDEEVLA-YSHSQGIPELREAFAKYYKKW-GIDVEPDE 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 108 CVpVT--GSMQGTFAsFLTCsqCDEKkDTILFIDP------GFpvqkqqLVVMGQKYETFDVYDYRGDKL--KEKLESYL 177
Cdd:PRK07568  91 IL-ITngGSEAILFA-MMAI--CDPG-DEILVPEPfyanynGF------ATSAGVKIVPVTTKIEEGFHLpsKEEIEKLI 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 178 KKgNISAVIYSNPNNPSWICLKDEELKIIGELATQYDVIVLEDLAY--FAMDfrqdlSTPYHapyqpSVAHYT---DNYI 252
Cdd:PRK07568 160 TP-KTKAILISNPGNPTGVVYTKEELEMLAEIAKKHDLFLISDEVYreFVYD-----GLKYT-----SALSLEgleDRVI 228

                        250
                 ....*....|....*...
gi 492291028 253 LLISGSKAFSYAGQRIGV 270
Cdd:PRK07568 229 IIDSVSKRYSACGARIGC 246
PRK07682 PRK07682
aminotransferase;
64-277 6.85e-08

aminotransferase;


Pssm-ID: 181082 [Multi-domain]  Cd Length: 378  Bit Score: 54.36  E-value: 6.85e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  64 KAEIEALQNGIASlYPDINGLPELKSEASKFIKAFIDIDLKPEGCVPVT-GSMQgtfASFLTCSQCDEKKDTILFIDPGF 142
Cdd:PRK07682  40 EASIRSLEQGYTS-YTANAGLLELRQEIAKYLKKRFAVSYDPNDEIIVTvGASQ---ALDVAMRAIINPGDEVLIVEPSF 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 143 pVQKQQLVVM-GQKYETFDVYDYRGDKLK-EKLESYLKKgNISAVIYSNPNNPSWICLKDEELKIIGELATQYDVIVLED 220
Cdd:PRK07682 116 -VSYAPLVTLaGGVPVPVATTLENEFKVQpAQIEAAITA-KTKAILLCSPNNPTGAVLNKSELEEIAVIVEKHDLIVLSD 193

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 221 LAYFAMdfrqdlstPYHAPYQ--PSVAHYTDNYIlLISG-SKAFSYAGQRIGVSCISDKL 277
Cdd:PRK07682 194 EIYAEL--------TYDEAYTsfASIKGMRERTI-LISGfSKGFAMTGWRLGFIAAPVYF 244
PLN00175 PLN00175
aminotransferase family protein; Provisional
 15-375 8.32e-08

aminotransferase family protein; Provisional


Pssm-ID: 215089 [Multi-domain]  Cd Length: 413  Bit Score: 54.10  E-value: 8.32e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  15 IEEFQITDFSKATIREVKAIAakaetasgvefIKMEMGVPGLPPSTVGVKAEIEALQNGiASLYPDINGLPELKSEASKF 94
Cdd:PLN00175  36 LEKFKTTIFTQMSSLAIKHGA-----------INLGQGFPNFDGPDFVKEAAIQAIRDG-KNQYARGFGVPELNSAIAER 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  95 IKAFIDIDLKPEGCVPVTgsmqgtfasfltcSQCDEK-KDTIL-FIDPGfpvqkQQLVVMGQKYETFD-VYDYRGDKLK- 170
Cdd:PLN00175 104 FKKDTGLVVDPEKEVTVT-------------SGCTEAiAATILgLINPG-----DEVILFAPFYDSYEaTLSMAGAKIKt 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 171 ------------EKLESYLKKgNISAVIYSNPNNPSWICLKDEELKIIGELATQYDVIVLEDLAYFAMDFRQDlstpyHA 238
Cdd:PLN00175 166 vtlrppdfavpeDELKAAFTS-KTRAILINTPHNPTGKMFTREELELIASLCKENDVLAFTDEVYDKLAFEGD-----HI 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 239 pyqpSVAHYTDNY---ILLISGSKAFSYAGQRIGVSCISDKLyhrhypgfdkrygggTFGTVFIHRVlyaLSSGTSHSAQ 315
Cdd:PLN00175 240 ----SMASLPGMYertVTMNSLGKTFSLTGWKIGWAIAPPHL---------------TWGVRQAHSF---LTFATATPMQ 297

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 316 FAMAAMLKAAnEGKYNFLneVRIYGERARKLKEIFLRYGFHlVYDkdledpvADGFYFTI 375
Cdd:PLN00175 298 WAAVAALRAP-ESYYEEL--KRDYSAKKDILVEGLKEVGFK-VYP-------SSGTYFVM 346
PRK09148 PRK09148
LL-diaminopimelate aminotransferase;
28-269 1.27e-07

LL-diaminopimelate aminotransferase;


Pssm-ID: 181674 [Multi-domain]  Cd Length: 405  Bit Score: 53.53  E-value: 1.27e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  28 IREVKAIAAKAEtASGVEFIKMEMGVPGLPPSTVGVKAEIEALQNGIASLYPDINGLPEL-KSEASKFIKAFiDIDLKPE 106
Cdd:PRK09148  15 FEQVNRLKAAAR-AAGADIIDLGMGNPDLPTPQHIVDKLCETAQDPRTHRYSASKGIPGLrRAQAAYYARRF-GVKLNPD 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 107 GCVPVT-GSMQGtFASFLTCsqCDEKKDTILFIDPGFPVQKQQLVVMGQKYETFDVydyrgdklkEKLESYLK------K 179
Cdd:PRK09148  93 TQVVATlGSKEG-FANMAQA--ITAPGDVILCPNPSYPIHAFGFIMAGGVIRSVPA---------EPDEEFFPaleravR 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 180 GNI---SAVIYSNPNNPSWICLKDEELKIIGELATQYDVIVLEDLAYFAMDFrqDLSTPyhapyqPSVAHY---TDNYIL 253
Cdd:PRK09148 161 HSIpkpIALIVNYPSNPTAYVADLDFYKDVVAFAKKHDIIILSDLAYSEIYF--DGNPP------PSVLQVpgaKDVTVE 232

                        250
                 ....*....|....*.
gi 492291028 254 LISGSKAFSYAGQRIG 269
Cdd:PRK09148 233 FTSMSKTFSMAGWRMG 248
MalY COG1168
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor ...
 171-339 3.86e-07

Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440782  Cd Length: 387  Bit Score: 52.02  E-value: 3.86e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 171 EKLESYLKkGNISAVIYSNPNNPSWICLKDEELKIIGELATQYDVIVL--E---DLAYFamDFRqdlstpyHAPYQPSVA 245
Cdd:COG1168  152 DDLEAKLD-PGVKLLLLCNPHNPTGRVWTREELERLAELCERHDVLVIsdEihaDLVLP--GHK-------HTPFASLSE 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 246 HYTDNYILLISGSKAFSYAGQRIGVSCISDKLYHRHYpgfdkrygggtfgtvfiHRVLYALssGTSHSAQFAMAAMLKAA 325
Cdd:COG1168  222 EAADRTITLTSPSKTFNLAGLKASYAIIPNPALRARF-----------------ARALEGL--GLPSPNVLGLVATEAAY 282

                        170
                 ....*....|....
gi 492291028 326 NEGkYNFLNEVRIY 339
Cdd:COG1168  283 REG-EEWLDELLAY 295
PRK08068 PRK08068
transaminase; Reviewed
 31-269 8.67e-07

transaminase; Reviewed


Pssm-ID: 181219  Cd Length: 389  Bit Score: 50.69  E-value: 8.67e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  31 VKAIAAKaeTASGVEFIKMEMGVPGLPPSTVGVKAEIEALQNGIASLYPDINGLPELKSEASKFIKAFIDIDLKPEGCVP 110
Cdd:PRK08068  21 VAKVNKK--VAEGHDVINLGQGNPDQPTPEHIVEALQEAAENPANHKYSPFRGYPFLKEAAADFYKREYGVTLDPETEVA 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 111 VTGsmqGTFASFLTCSQC-DEKKDTILFIDPGFPVQKQQLVVMGQKYETFDVY-------DYrgDKLKEKLesyLKKgni 182
Cdd:PRK08068  99 ILF---GGKAGLVELPQClMNPGDTILVPDPGYPDYLSGVALARAQFETMPLIaennflpDY--TKIPEEV---AEK--- 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 183 SAVIYSN-PNNPSWICLKDEELKIIGELATQYDVIVLEDLAYFAMDFrqDLSTP---YHAPYQPSVAhytdnyILLISGS 258
Cdd:PRK08068 168 AKLMYLNyPNNPTGAVATKAFFEETVAFAKKHNIGVVHDFAYGAIGF--DGQKPvsfLQTPGAKDVG------IELYTLS 239

                        250
                 ....*....|.
gi 492291028 259 KAFSYAGQRIG 269
Cdd:PRK08068 240 KTFNMAGWRVA 250
avtA PRK09440
valine--pyruvate transaminase; Provisional
 180-270 2.35e-05

valine--pyruvate transaminase; Provisional


Pssm-ID: 236517  Cd Length: 416  Bit Score: 46.39  E-value: 2.35e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 180 GNISAVIYSNPNNPSWICLKDEELKIIGELATQYDVIVLEDLAYfamdfrqdlSTPYhapyqPSVA------HYTDNYIL 253
Cdd:PRK09440 178 EDTGAICVSRPTNPTGNVLTDEELEKLDALARQHNIPLLIDNAY---------GPPF-----PGIIfseatpLWNPNIIL 243

                         90
                 ....*....|....*..
gi 492291028 254 LISGSKAfSYAGQRIGV 270
Cdd:PRK09440 244 CMSLSKL-GLPGVRCGI 259
PRK07777 PRK07777
putative succinyldiaminopimelate transaminase DapC;
58-272 2.58e-05

putative succinyldiaminopimelate transaminase DapC;


Pssm-ID: 236095 [Multi-domain]  Cd Length: 387  Bit Score: 46.18  E-value: 2.58e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  58 PSTVGVKAEIEALQNGIAS---LYPDINGLPELKSEASKFIKAFIDIDLKPEGCVPVT-GSMQGTFASFLTCSqcdEKKD 133
Cdd:PRK07777  34 PDEDGPPEMLEAAQEAIAGgvnQYPPGPGIPELRAAIAAQRRRRYGLEYDPDTEVLVTvGATEAIAAAVLGLV---EPGD 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 134 TILFIDPGF---------------PVQkqqLVVMGQKYeTFDVydyrgDKLKEKLESYLKkgnisAVIYSNPNNPSWICL 198
Cdd:PRK07777 111 EVLLIEPYYdsyaaviamagahrvPVP---LVPDGRGF-ALDL-----DALRAAVTPRTR-----ALIVNSPHNPTGTVL 176

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492291028 199 KDEELKIIGELATQYDVIVLEDLAYFAMDFrqdlSTPYHAPYQ--PSVAHYTdnyILLISGSKAFSYAGQRIGVSC 272
Cdd:PRK07777 177 TAAELAAIAELAVEHDLLVITDEVYEHLVF----DGARHLPLAtlPGMRERT---VTISSAAKTFNVTGWKIGWAC 245
PRK08960 PRK08960
pyridoxal phosphate-dependent aminotransferase;
36-269 4.65e-05

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181595  Cd Length: 387  Bit Score: 45.43  E-value: 4.65e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  36 AKAETASGVEFIKMEMGVPGLPPSTVGVKAEIEALQNGiASLYPDINGLPELKSEASKFIKAFIDIDLKPEGCVPVTGsm 115
Cdd:PRK08960  24 ANELEAAGHDVIHLEIGEPDFTTAEPIVAAGQAALAAG-HTRYTAARGLPALREAIAGFYAQRYGVDVDPERILVTPG-- 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 116 qGTFASFLTCSQCDEKKDTILFIDPGFPVQKQ---------QLVVMGQkyetfdvyDYRGDKLKEKLESYLKKGNISAVI 186
Cdd:PRK08960 101 -GSGALLLASSLLVDPGKHWLLADPGYPCNRHflrlvegaaQLVPVGP--------DSRYQLTPALVERHWNADTVGALV 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 187 YSnPNNPSWICLKDEELKIIGELATQYDVIVLEDLAYFAMDFRQDlstpyhapyQPSVAHYTDNYILLISGSKAFSYAGQ 266
Cdd:PRK08960 172 AS-PANPTGTLLSRDELAALSQALRARGGHLVVDEIYHGLTYGVD---------AASVLEVDDDAFVLNSFSKYFGMTGW 241


                 ...
gi 492291028 267 RIG 269
Cdd:PRK08960 242 RLG 244
PLN00145 PLN00145
tyrosine/nicotianamine aminotransferase; Provisional
 63-223 2.48e-04

tyrosine/nicotianamine aminotransferase; Provisional


Pssm-ID: 215074 [Multi-domain]  Cd Length: 430  Bit Score: 43.22  E-value: 2.48e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  63 VKAEIEALQNGIASLYPDINGLPELKSEASKFIKAFIDIDLKPEGCVPVTGSMQgtfASFLTCSQCDEKKDTILFIDPGF 142
Cdd:PLN00145  75 EDAVAAALRSGKYNSYSTCVGLLPARRAIAEYLSRDLPYELSTDDIYLTAGCAQ---AIEIIMSVLAQPGANILLPRPGY 151

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 143 PVQKQQLVVMGQKYETFDVYDYRGDKLK-EKLESyLKKGNISAVIYSNPNNPSWICLKDEELKIIGELATQYDVIVLEDL 221
Cdd:PLN00145 152 PLYEARAVFSGLEVRHFDLLPERGWEVDlEGVEA-LADENTVAMVIINPNNPCGSVYSYEHLAKIAETARKLGILVIADE 230


                 ..
gi 492291028 222 AY 223
Cdd:PLN00145 231 VY 232
tyr_nico_aTase TIGR01265
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ...
 54-269 2.93e-04

tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.


Pssm-ID: 188123  Cd Length: 403  Bit Score: 42.71  E-value: 2.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028   54 PGLPPSTVGVKAEIEALQNGIASLYPDINGLPELKSEASKFIKAFIDIDLKPEGCVPVTGSMQG---TFASFLTCSQcde 130
Cdd:TIGR01265  45 GNLRTDPEAEEAVKDALRSGKFNGYAPSVGALAAREAVAEYLSSDLPGKLTADDVVLTSGCSQAieiCIEALANPGA--- 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  131 kkdTILFIDPGFPVQKQQLVVMGQKYETFDVY---DYRGDkLKEkLESyLKKGNISAVIYSNPNNPSWICLKDEELKIIG 207
Cdd:TIGR01265 122 ---NILVPRPGFPLYDTRAAFSGLEVRLYDLLpekDWEID-LDG-LES-LADEKTVAIVVINPSNPCGSVFSRDHLQKIA 195

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492291028  208 ELATQYDVIVLEDLAYFAMDFRQdlstpyhAPYQPsVAHYTDNYILLISG--SKAFSYAGQRIG 269
Cdd:TIGR01265 196 EVAEKLGIPIIADEIYGHMVFGD-------APFIP-MASFASIVPVLSLGgiSKRWVVPGWRLG 251
tyr_amTase_E TIGR01264
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ...
 21-276 3.17e-04

tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]


Pssm-ID: 273529 [Multi-domain]  Cd Length: 401  Bit Score: 42.85  E-value: 3.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028   21 TDFSKATIREVKAIA--AKAETASGVEFIKMEMGVP----GLPPSTVGVKAEIEALQNGIASLYPDINGLPELKSEASKF 94
Cdd:TIGR01264   6 SDHSKNTVNPIRAIVdnMKVKPNPEKPMIKLSIGDPtvfgNLPTDPEVMQAMKDSLDSGKYNGYAPTVGALSAREAIASY 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028   95 iKAFIDIDLKPEGCVPVTGSMQGTFASFLTCsqCDeKKDTILFIDPGFPVQKQQLVVMGQKYETFDVY---DYRGDkLKE 171
Cdd:TIGR01264  86 -YHNPDGPIEADDVVLCSGCSHAIEMCIAAL--AN-AGQNILVPRPGFPLYETLAESMGIEVKLYNLLpdkSWEID-LKQ 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  172 kLESyLKKGNISAVIYSNPNNPSWICLKDEELKIIGELATQYDVIVLEDLAYFAMDFRQDLSTPyhapyqpsVAHYTDNY 251
Cdd:TIGR01264 161 -LES-LIDEKTAALIVNNPSNPCGSVFSRQHLEEILAVAERQCLPIIADEIYGDMVFSGATFEP--------LASLSSTV 230

                         250       260
                  ....*....|....*....|....*..
gi 492291028  252 ILLISG--SKAFSYAGQRIGVSCISDK 276
Cdd:TIGR01264 231 PILSCGglAKRWLVPGWRLGWIIIHDR 257
PRK13355 PRK13355
bifunctional HTH-domain containing protein/aminotransferase; Provisional
 184-269 5.19e-04

bifunctional HTH-domain containing protein/aminotransferase; Provisional


Pssm-ID: 237361 [Multi-domain]  Cd Length: 517  Bit Score: 42.42  E-value: 5.19e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 184 AVIYSNPNNPSWICLKDEELKIIGELATQYDVIVLEDLAY--FAMDFRQDLSTPYHAPyqpsvahytDNYILLISG-SKA 260
Cdd:PRK13355 284 AIVIINPNNPTGALYPREVLQQIVDIAREHQLIIFSDEIYdrLVMDGLEHTSIASLAP---------DLFCVTFSGlSKS 354


                 ....*....
gi 492291028 261 FSYAGQRIG 269
Cdd:PRK13355 355 HMIAGYRIG 363
PLN02656 PLN02656
tyrosine transaminase
 39-303 5.87e-04

tyrosine transaminase


Pssm-ID: 178262 [Multi-domain]  Cd Length: 409  Bit Score: 41.83  E-value: 5.87e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  39 ETASGVEFIKMEMGVPGL----PPSTVGVKAEIEALQNGIASLYPDINGLPELKSEASKFIKAFIDIDLKPEGCVPVTGS 114
Cdd:PLN02656  26 DEENGKRVISLGMGDPTAyscfHTTHVAQEAVVDALQSNKFNGYAPTVGLPQARRAIAEYLSRDLPYKLSLDDVFITSGC 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 115 MQgtfASFLTCSQCDEKKDTILFIDPGFPVQKQQLVVMGQKYETFDVYDYRGDKLKEKLESYLKKGNISAVIYSNPNNPS 194
Cdd:PLN02656 106 TQ---AIDVALSMLARPGANILLPRPGFPIYELCAAFRHLEVRYVDLLPEKGWEVDLDAVEALADQNTVALVIINPGNPC 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 195 WICLKDEELKIIGELATQYDVIVLEDLAYFAMDFRQDlstpyhaPYQP-SVAHYTDNYILLISGSKAFSYAGQRIGVSCI 273
Cdd:PLN02656 183 GNVYSYQHLKKIAETAEKLKILVIADEVYGHLAFGSN-------PFVPmGVFGSIVPVLTLGSLSKRWIVPGWRLGWFVT 255

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 492291028 274 SD--------KLYHRHYPGFDKRYGGGTFGTVFIHRVL 303
Cdd:PLN02656 256 TDpsgsfrdpKIVERIKKYFDILGGPATFIQAAVPTIL 293
PRK09275 PRK09275
bifunctional aspartate transaminase/aspartate 4-decarboxylase;
167-290 7.97e-04

bifunctional aspartate transaminase/aspartate 4-decarboxylase;


Pssm-ID: 236444  Cd Length: 527  Bit Score: 41.77  E-value: 7.97e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 167 DKLKEKlesylkkgNISAVIYSNPNNPSWICLKDEELKIIGELATQY--DVIVLEDLAY--FAMDFRQDLSTpyhAPYqp 242
Cdd:PRK09275 235 EKLRDP--------SIKALFLVNPSNPPSVAMSDESLEKIADIVNEKrpDLMIITDDVYgtFVDDFRSLFAV---LPY-- 301

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 492291028 243 svahytdNYILLISGSKAFSYAGQRIGVSCIS-----DKLYhRHYPG-----FDKRYG 290
Cdd:PRK09275 302 -------NTILVYSFSKYFGATGWRLGVIALHednvfDKLI-AKLPEekkkeLDKRYS 351
PLN02187 PLN02187
rooty/superroot1
 65-223 1.16e-03

rooty/superroot1


Pssm-ID: 215119 [Multi-domain]  Cd Length: 462  Bit Score: 41.25  E-value: 1.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  65 AEIEALQNGIASLYPDINGLPELKSEASKFIKAFIDIDLKPEGCVPVTGSMQGTFASFLTCSQCDEkkdTILFIDPGFPV 144
Cdd:PLN02187  91 AVVDVLRSGKGNSYGPGAGILPARRAVADYMNRDLPHKLTPEDIFLTAGCNQGIEIVFESLARPNA---NILLPRPGFPH 167

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492291028 145 QKQQLVVMGQKYETFDVYDYRGDKLKEKLESYLKKGNISAVIYSNPNNPSWICLKDEELKIIGELATQYDVIVLEDLAY 223
Cdd:PLN02187 168 YDARAAYSGLEVRKFDLLPEKEWEIDLEGIEAIADENTVAMVVINPNNPCGNVYSHDHLKKVAETARKLGIMVISDEVY 246
PRK07324 PRK07324
transaminase; Validated
 189-269 1.61e-03

transaminase; Validated


Pssm-ID: 235989  Cd Length: 373  Bit Score: 40.31  E-value: 1.61e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 189 NPNNPSWICLKDEELKIIGELATQYDVIVLEDLAYfaMDFRQDLSTpyhapyqPSVAHYTDNYILLISGSKAFSYAGQRI 268
Cdd:PRK07324 161 NANNPTGALMDRAYLEEIVEIARSVDAYVLSDEVY--RPLDEDGST-------PSIADLYEKGISTNSMSKTYSLPGIRV 231


                 .
gi 492291028 269 G 269
Cdd:PRK07324 232 G 232
PRK06836 PRK06836
pyridoxal phosphate-dependent aminotransferase;
184-303 1.99e-03

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180720  Cd Length: 394  Bit Score: 40.18  E-value: 1.99e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 184 AVIYSNPNNPSWICLKDEELKIIGEL----ATQY--DVIVLEDLAY--FAMDFRQdlstpyhapyQPSVAHYTDNYILLI 255
Cdd:PRK06836 171 AVIINSPNNPTGVVYSEETLKALAALleekSKEYgrPIYLISDEPYreIVYDGAE----------VPYIFKYYDNSIVVY 240

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 492291028 256 SGSKAFSYAGQRIGVSCISDKLyhrhyPGFDKRYGggtfGTVFIHRVL 303
Cdd:PRK06836 241 SFSKSLSLPGERIGYIAVNPEM-----EDADDLVA----ALVFANRIL 279
PRK05166 PRK05166
histidinol-phosphate transaminase;
133-275 2.49e-03

histidinol-phosphate transaminase;


Pssm-ID: 179950  Cd Length: 371  Bit Score: 39.74  E-value: 2.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 133 DTILFIDPGFPVQKQQLVVMGQKYETFDVYDYRGDKLKEKLESYLKKGNIsaVIYSNPNNP--SWIClKDEELKIIGELA 210
Cdd:PRK05166 113 DRVVTLYPSFPLHEDYPTMMGARVERVTVTPDLGFDLDALCAAVARAPRM--LMFSNPSNPvgSWLT-ADQLARVLDATP 189

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492291028 211 TQYDVIVLEDLAYFAmdfrqdlstpyHAPYQPSVAHYTD----NYILLISGSKAFSYAGQRIGVSCISD 275
Cdd:PRK05166 190 PETLIVVDEAYAEYA-----------AGDDYPSALTLLKarglPWIVLRTFSKAYGLAGLRVGYGLVSD 247
PLN02368 PLN02368
alanine transaminase
 57-223 4.81e-03

alanine transaminase


Pssm-ID: 177996 [Multi-domain]  Cd Length: 407  Bit Score: 39.01  E-value: 4.81e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  57 PPSTVGVKAEIEALQNGIASLYPDINGLPELKSEASKFIKAFIDIDLKPEGCVPVTGSMQGTfASFLTCSQCDEKkDTIL 136
Cdd:PLN02368  82 PADAIARAKHYLSLTSGGLGAYSDSRGLPGVRKEVAEFIERRDGYPSDPELIFLTDGASKGV-MQILNAVIRGEK-DGVL 159

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 137 FIDPGFPVQKQQLVVMGQKYETFDVYDYRG-----DKLKEKLESYLKKG-NISAVIYSNPNNPSWICLKDEELKIIGELA 210
Cdd:PLN02368 160 VPVPQYPLYSATISLLGGTLVPYYLEESENwgldvNNLRQSVAQARSKGiTVRAMVIINPGNPTGQCLSEANLREILKFC 239

                        170
                 ....*....|...
gi 492291028 211 TQYDVIVLEDLAY 223
Cdd:PLN02368 240 YQERLVLLGDEVY 252
PRK06108 PRK06108
pyridoxal phosphate-dependent aminotransferase;
35-269 5.00e-03

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180404  Cd Length: 382  Bit Score: 38.77  E-value: 5.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028  35 AAKAETASG-VEFIKMEMGVPGLPPSTVG----------VKAEIEALQNGiASLYPDINGLPELKSEASKFIKAFIDIDL 103
Cdd:PRK06108   4 AARALPESGiREVANAGRGREGVLPLWFGesdlptpdfiRDAAAAALADG-ETFYTHNLGIPELREALARYVSRLHGVAT 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 104 KPEGcVPVTGS-MQG-TFASFLTCSQCDEkkdtILFIDPGFPVQKQQLVVMGQKYETFDVyDYRGDKLK---EKLESYLK 178
Cdd:PRK06108  83 PPER-IAVTSSgVQAlMLAAQALVGPGDE----VVAVTPLWPNLVAAPKILGARVVCVPL-DFGGGGWTldlDRLLAAIT 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492291028 179 KGNiSAVIYSNPNNPSWICLKDEELKIIGELATQYDVIVLED----LAYFAMDFRqdlstpyhAPYQPSVAHYTDNYILL 254
Cdd:PRK06108 157 PRT-RALFINSPNNPTGWTASRDDLRAILAHCRRHGLWIVADevyeRLYYAPGGR--------APSFLDIAEPDDRIIFV 227

                        250
                 ....*....|....*
gi 492291028 255 ISGSKAFSYAGQRIG 269
Cdd:PRK06108 228 NSFSKNWAMTGWRLG 242
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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