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Conserved domains on  [gi|492246715|ref|WP_005788411|]
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MULTISPECIES: 6-bladed beta-propeller [Bacteroides]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF5128 super family cl44435
6-bladed beta-propeller; This family is a 6-bladed beta-propeller structure of unknown ...
 56-191 1.49e-11

6-bladed beta-propeller; This family is a 6-bladed beta-propeller structure of unknown function. There is a highly conserved FDxxG motif which might be important.


The actual alignment was detected with superfamily member pfam17170:

Pssm-ID: 407298 [Multi-domain]  Cd Length: 321  Bit Score: 65.04  E-value: 1.49e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492246715   56 DLSLLKDTVDLPFSFFLKDFQIIKLDNRDEAMVGE-NNLCVSENYILVYGS----VYelhpcrLFTKKGEFVTNIGAIGQ 130
Cdd:pfam17170  11 TVIDFDEDKDVKLSSLFDSVEFIPLETTDSCLIGDiSRIKFVDDRIFVFDSntnnLF------VFDKKGKFVRQIGAQGN 84

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492246715  131 GPGEYRAVYKAEIDEKHNCIYLMPFDNsNAIYVYDLAG-KPLRSIPLHQSVSkAVFKVDADK 191
Cdd:pfam17170  85 GPGEYLQINDFIIDKSNNSIYILDFMQ-NKILTYDLDGySFIGEINLDLLPS-DCCQLDKGK 144
 
Name Accession Description Interval E-value
DUF5128 pfam17170
6-bladed beta-propeller; This family is a 6-bladed beta-propeller structure of unknown ...
 56-191 1.49e-11

6-bladed beta-propeller; This family is a 6-bladed beta-propeller structure of unknown function. There is a highly conserved FDxxG motif which might be important.


Pssm-ID: 407298 [Multi-domain]  Cd Length: 321  Bit Score: 65.04  E-value: 1.49e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492246715   56 DLSLLKDTVDLPFSFFLKDFQIIKLDNRDEAMVGE-NNLCVSENYILVYGS----VYelhpcrLFTKKGEFVTNIGAIGQ 130
Cdd:pfam17170  11 TVIDFDEDKDVKLSSLFDSVEFIPLETTDSCLIGDiSRIKFVDDRIFVFDSntnnLF------VFDKKGKFVRQIGAQGN 84

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492246715  131 GPGEYRAVYKAEIDEKHNCIYLMPFDNsNAIYVYDLAG-KPLRSIPLHQSVSkAVFKVDADK 191
Cdd:pfam17170  85 GPGEYLQINDFIIDKSNNSIYILDFMQ-NKILTYDLDGySFIGEINLDLLPS-DCCQLDKGK 144
NHL_like_5 cd14963
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) ...
 115-174 6.64e-04

Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.


Pssm-ID: 271333 [Multi-domain]  Cd Length: 268  Bit Score: 41.12  E-value: 6.64e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492246715 115 FTKKGEFVTNIGAIGQGPGEYRAVYKAEIDEKHNcIYLMpfD-NSNAIYVYDLAGKPLRSI 174
Cdd:cd14963  127 FDLEGKLLLEFGKPGSEPGELSYPNGIAVDEDGN-IYVA--DsGNGRIQVFDKNGKFIKEL 184
 
Name Accession Description Interval E-value
DUF5128 pfam17170
6-bladed beta-propeller; This family is a 6-bladed beta-propeller structure of unknown ...
 56-191 1.49e-11

6-bladed beta-propeller; This family is a 6-bladed beta-propeller structure of unknown function. There is a highly conserved FDxxG motif which might be important.


Pssm-ID: 407298 [Multi-domain]  Cd Length: 321  Bit Score: 65.04  E-value: 1.49e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492246715   56 DLSLLKDTVDLPFSFFLKDFQIIKLDNRDEAMVGE-NNLCVSENYILVYGS----VYelhpcrLFTKKGEFVTNIGAIGQ 130
Cdd:pfam17170  11 TVIDFDEDKDVKLSSLFDSVEFIPLETTDSCLIGDiSRIKFVDDRIFVFDSntnnLF------VFDKKGKFVRQIGAQGN 84

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492246715  131 GPGEYRAVYKAEIDEKHNCIYLMPFDNsNAIYVYDLAG-KPLRSIPLHQSVSkAVFKVDADK 191
Cdd:pfam17170  85 GPGEYLQINDFIIDKSNNSIYILDFMQ-NKILTYDLDGySFIGEINLDLLPS-DCCQLDKGK 144
NHL_like_5 cd14963
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) ...
 115-174 6.64e-04

Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.


Pssm-ID: 271333 [Multi-domain]  Cd Length: 268  Bit Score: 41.12  E-value: 6.64e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492246715 115 FTKKGEFVTNIGAIGQGPGEYRAVYKAEIDEKHNcIYLMpfD-NSNAIYVYDLAGKPLRSI 174
Cdd:cd14963  127 FDLEGKLLLEFGKPGSEPGELSYPNGIAVDEDGN-IYVA--DsGNGRIQVFDKNGKFIKEL 184
NHL_like_5 cd14963
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) ...
 113-175 7.66e-03

Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.


Pssm-ID: 271333 [Multi-domain]  Cd Length: 268  Bit Score: 38.04  E-value: 7.66e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492246715 113 RLFTKKGEFVTNIGAIGQGPGEYRAVYKAEIDEKHNcIYLMPFDNSNaIYVYDLAGKPLRSIP 175
Cdd:cd14963   33 QVFDYEGKFKKSFGGPGTGPGEFKYPYGIAVDSDGN-IYVADLYNGR-IQVFDPDGKFLKYFP 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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