MULTISPECIES: Holliday junction resolvase RuvX [Bacteroides]
RuvX/YqgF family protein( domain architecture ID 10002777)
RuvX/YqgF family protein such as Holliday junction resolvase RuvX, which acts as a dimer, or the monomeric pre-16S rRNA-processing nuclease YqgF, which was shown to process the 5' end of pre-16S rRNA within 70S ribosomes in vitro
List of domain hits
Name | Accession | Description | Interval | E-value | |||
YqgF | COG0816 | YqgF/RuvX protein, pre-16S rRNA maturation RNase/Holliday junction resolvase/anti-termination ... |
1-134 | 5.16e-58 | |||
YqgF/RuvX protein, pre-16S rRNA maturation RNase/Holliday junction resolvase/anti-termination factor [Translation, ribosomal structure and biogenesis, Replication, recombination and repair, Transcription]; : Pssm-ID: 440578 Cd Length: 136 Bit Score: 176.02 E-value: 5.16e-58
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Name | Accession | Description | Interval | E-value | |||
YqgF | COG0816 | YqgF/RuvX protein, pre-16S rRNA maturation RNase/Holliday junction resolvase/anti-termination ... |
1-134 | 5.16e-58 | |||
YqgF/RuvX protein, pre-16S rRNA maturation RNase/Holliday junction resolvase/anti-termination factor [Translation, ribosomal structure and biogenesis, Replication, recombination and repair, Transcription]; Pssm-ID: 440578 Cd Length: 136 Bit Score: 176.02 E-value: 5.16e-58
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PRK00109 | PRK00109 | Holliday junction resolvase RuvX; |
1-136 | 7.66e-53 | |||
Holliday junction resolvase RuvX; Pssm-ID: 234639 Cd Length: 138 Bit Score: 163.01 E-value: 7.66e-53
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YqgF | cd16964 | putative pre-16S rRNA nuclease YqgF and RuvX family; Escherichia coli YqgF has been shown to ... |
4-134 | 1.05e-51 | |||
putative pre-16S rRNA nuclease YqgF and RuvX family; Escherichia coli YqgF has been shown to act as a pre-16S rRNA nuclease, presumably as a monomer. It is involved in the processing of pre-16S rRNA during ribosome maturation. The RuvX gene product from Mycobacterium tuberculosis was shown to act, in a dimeric form, as a Holliday junction resolvase (HJR). HJRs endonucleases specifically resolve Holliday junction DNA intermediates during homologous recombination. Holliday junctions are formed by the reciprocal exchange of strands between two DNA duplexes. HJRs occur in archaea, bacteria, and in the mitochondria of certain fungi; they may form homodimers and display structural similarity to RNase H and Hsp70. Pssm-ID: 438564 Cd Length: 132 Bit Score: 159.95 E-value: 1.05e-51
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RuvX | pfam03652 | Holliday junction resolvase; The central intermediate formed during mitotic and meiotic ... |
2-135 | 1.42e-50 | |||
Holliday junction resolvase; The central intermediate formed during mitotic and meiotic recombination is a four stranded DNA structure, also known as the Holliday junction (HJ), and its efficient resolution is essential for proper segregation of chromosomes. Resolution of HJs is mediated by a diverse group of DNA structure specific endonucleases known as Holliday junction resolvases (HJR). This entry is specific for RuvX also known as YqgF a family of nucleases which resolves the Holliday junction intermediates in genetic recombination. Studies carried out in M. tuberculosis, have shown that YqgF/RuvX is a genuine HJR analogous to RuvC from E. coli. Furthermore, a single cysteine present in M. tuberculosis RuvX was found to be required for disulfide-bond mediated intermolecular dimerization and HJ resolution activity, suggesting that M. tuberculosis RuvX has adapted its YqgF protein to function like a typical RuvC family HJR. Pssm-ID: 461005 Cd Length: 134 Bit Score: 157.29 E-value: 1.42e-50
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RNAse_H_YqgF | TIGR00250 | putative transcription antitermination factor YqgF; This protein family, which exhibits an ... |
5-134 | 3.68e-24 | |||
putative transcription antitermination factor YqgF; This protein family, which exhibits an RNAse H fold in crystal structure, has been proposed as a putative Holliday junction resolvase, an alternate to RuvC. [Unknown function, General] Pssm-ID: 129352 Cd Length: 130 Bit Score: 90.27 E-value: 3.68e-24
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YqgFc | smart00732 | Likely ribonuclease with RNase H fold; YqgF proteins are likely to function as an alternative ... |
3-98 | 3.59e-20 | |||
Likely ribonuclease with RNase H fold; YqgF proteins are likely to function as an alternative to RuvC in most bacteria, and could be the principal holliday junction resolvases in low-GC Gram-positive bacteria. In Spt6p orthologues, the catalytic residues are substituted indicating that they lack enzymatic functions. Pssm-ID: 128971 Cd Length: 99 Bit Score: 79.15 E-value: 3.59e-20
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Name | Accession | Description | Interval | E-value | |||
YqgF | COG0816 | YqgF/RuvX protein, pre-16S rRNA maturation RNase/Holliday junction resolvase/anti-termination ... |
1-134 | 5.16e-58 | |||
YqgF/RuvX protein, pre-16S rRNA maturation RNase/Holliday junction resolvase/anti-termination factor [Translation, ribosomal structure and biogenesis, Replication, recombination and repair, Transcription]; Pssm-ID: 440578 Cd Length: 136 Bit Score: 176.02 E-value: 5.16e-58
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PRK00109 | PRK00109 | Holliday junction resolvase RuvX; |
1-136 | 7.66e-53 | |||
Holliday junction resolvase RuvX; Pssm-ID: 234639 Cd Length: 138 Bit Score: 163.01 E-value: 7.66e-53
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YqgF | cd16964 | putative pre-16S rRNA nuclease YqgF and RuvX family; Escherichia coli YqgF has been shown to ... |
4-134 | 1.05e-51 | |||
putative pre-16S rRNA nuclease YqgF and RuvX family; Escherichia coli YqgF has been shown to act as a pre-16S rRNA nuclease, presumably as a monomer. It is involved in the processing of pre-16S rRNA during ribosome maturation. The RuvX gene product from Mycobacterium tuberculosis was shown to act, in a dimeric form, as a Holliday junction resolvase (HJR). HJRs endonucleases specifically resolve Holliday junction DNA intermediates during homologous recombination. Holliday junctions are formed by the reciprocal exchange of strands between two DNA duplexes. HJRs occur in archaea, bacteria, and in the mitochondria of certain fungi; they may form homodimers and display structural similarity to RNase H and Hsp70. Pssm-ID: 438564 Cd Length: 132 Bit Score: 159.95 E-value: 1.05e-51
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RuvX | pfam03652 | Holliday junction resolvase; The central intermediate formed during mitotic and meiotic ... |
2-135 | 1.42e-50 | |||
Holliday junction resolvase; The central intermediate formed during mitotic and meiotic recombination is a four stranded DNA structure, also known as the Holliday junction (HJ), and its efficient resolution is essential for proper segregation of chromosomes. Resolution of HJs is mediated by a diverse group of DNA structure specific endonucleases known as Holliday junction resolvases (HJR). This entry is specific for RuvX also known as YqgF a family of nucleases which resolves the Holliday junction intermediates in genetic recombination. Studies carried out in M. tuberculosis, have shown that YqgF/RuvX is a genuine HJR analogous to RuvC from E. coli. Furthermore, a single cysteine present in M. tuberculosis RuvX was found to be required for disulfide-bond mediated intermolecular dimerization and HJ resolution activity, suggesting that M. tuberculosis RuvX has adapted its YqgF protein to function like a typical RuvC family HJR. Pssm-ID: 461005 Cd Length: 134 Bit Score: 157.29 E-value: 1.42e-50
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RNAse_H_YqgF | TIGR00250 | putative transcription antitermination factor YqgF; This protein family, which exhibits an ... |
5-134 | 3.68e-24 | |||
putative transcription antitermination factor YqgF; This protein family, which exhibits an RNAse H fold in crystal structure, has been proposed as a putative Holliday junction resolvase, an alternate to RuvC. [Unknown function, General] Pssm-ID: 129352 Cd Length: 130 Bit Score: 90.27 E-value: 3.68e-24
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YqgFc | smart00732 | Likely ribonuclease with RNase H fold; YqgF proteins are likely to function as an alternative ... |
3-98 | 3.59e-20 | |||
Likely ribonuclease with RNase H fold; YqgF proteins are likely to function as an alternative to RuvC in most bacteria, and could be the principal holliday junction resolvases in low-GC Gram-positive bacteria. In Spt6p orthologues, the catalytic residues are substituted indicating that they lack enzymatic functions. Pssm-ID: 128971 Cd Length: 99 Bit Score: 79.15 E-value: 3.59e-20
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Blast search parameters | ||||
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