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Conserved domains on  [gi|491531901|ref|WP_005389524|]
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MULTISPECIES: ABC transporter permease [Vibrio]

Protein Classification

TupA family protein( domain architecture ID 10790812)

TupA family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TupA COG4662
ABC-type tungstate transport system, periplasmic component [Inorganic ion transport and ...
 3-231 4.05e-106

ABC-type tungstate transport system, periplasmic component [Inorganic ion transport and metabolism];


:

Pssm-ID: 443699 [Multi-domain]  Cd Length: 232  Bit Score: 305.49  E-value: 4.05e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901   3 LADTTLEALRLLVNFDADLWEIVAVSFSVSITAISLVVLPAILMSFVLAYTDFRGKWFLLSIVNTLQAVPTVVIGLLLYM 82
Cdd:COG4662    4 ILEGFAEALRLLLSGDPELWEIVLLSLRVSLTATLIAALIGLPLGALLALKRFPGRRLVISLLNTLMGLPPVVVGLLVYL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  83 LLSRAGPWGDWQMLFTQKAMIFGQMVICFPVLVSMMHGALQSSDRRAVETAITLGVSIPRLAATMIWETRFPLLAAIIAG 162
Cdd:COG4662   84 LLSRSGPLGFLGLLFTPTAMIIAQTVLALPIVAALTRAAVEDLDRRLRETLRSLGASRLQALLTLLWEARFGLLAAVLAG 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 491531901 163 FSRIVTEVGCSMMVGGNIMGVTRNIPTAIAMESSKGAFAQGVALGIVLLSLALALNFFLSSMRGKGYLR 231
Cdd:COG4662  164 FGRAISEVGAVMMVGGNIKGYTRVMTTAIALETSKGEFALAIALGIVLLAIALLVNALLSLLQGRGRRR 232
 
Name Accession Description Interval E-value
TupA COG4662
ABC-type tungstate transport system, periplasmic component [Inorganic ion transport and ...
 3-231 4.05e-106

ABC-type tungstate transport system, periplasmic component [Inorganic ion transport and metabolism];


Pssm-ID: 443699 [Multi-domain]  Cd Length: 232  Bit Score: 305.49  E-value: 4.05e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901   3 LADTTLEALRLLVNFDADLWEIVAVSFSVSITAISLVVLPAILMSFVLAYTDFRGKWFLLSIVNTLQAVPTVVIGLLLYM 82
Cdd:COG4662    4 ILEGFAEALRLLLSGDPELWEIVLLSLRVSLTATLIAALIGLPLGALLALKRFPGRRLVISLLNTLMGLPPVVVGLLVYL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  83 LLSRAGPWGDWQMLFTQKAMIFGQMVICFPVLVSMMHGALQSSDRRAVETAITLGVSIPRLAATMIWETRFPLLAAIIAG 162
Cdd:COG4662   84 LLSRSGPLGFLGLLFTPTAMIIAQTVLALPIVAALTRAAVEDLDRRLRETLRSLGASRLQALLTLLWEARFGLLAAVLAG 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 491531901 163 FSRIVTEVGCSMMVGGNIMGVTRNIPTAIAMESSKGAFAQGVALGIVLLSLALALNFFLSSMRGKGYLR 231
Cdd:COG4662  164 FGRAISEVGAVMMVGGNIKGYTRVMTTAIALETSKGEFALAIALGIVLLAIALLVNALLSLLQGRGRRR 232
ABC_perm1 NF038017
ABC transporter permease; Proteins of this family are the permease subunit of an ABC ...
 28-211 3.90e-57

ABC transporter permease; Proteins of this family are the permease subunit of an ABC transporter complex, which may be involved in tungstate uptake.


Pssm-ID: 411610 [Multi-domain]  Cd Length: 184  Bit Score: 179.66  E-value: 3.90e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  28 SFSVSITAISLVVLPAILMSFVLAYTDFRGKWFLLSIVNTLQAVPTVVIGLLLYMLLSRAGPWGDWQMLFTQKAMIFGQM 107
Cdd:NF038017   1 SLRVSGTATLIAALIGIPLGALLALRRFPGRRLVISLLNTLMGLPPVVVGLIVYLLLSRSGPLGFLGLLYTPTAMIIAQA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901 108 VICFPVLVSMMHGALQSSDRRAVETAITLGVSIPRLAATMIWETRFPLLAAIIAGFSRIVTEVGCSMMVGGNIMGVTRNI 187
Cdd:NF038017  81 VLALPIVAGLTLAAVQGLDPELRLQILSLGATRWQALWTLLKEARFALLAAVLAGFGRAISEVGAVMMVGGNIRGYTRVL 160

                        170       180
                 ....*....|....*....|....
gi 491531901 188 PTAIAMESSKGAFAQGVALGIVLL 211
Cdd:NF038017 161 TTAIVLETSKGNFDLALALGIILL 184
modB PRK09421
molybdate ABC transporter permease subunit;
22-217 7.82e-20

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 84.59  E-value: 7.82e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  22 WEIVAVSFSVSITAISLVVLPAILMSFVLAYTDFRGKWFLLSIVNTLQAVPTVVIGLLLYMLLSRAGPWGDW-------Q 94
Cdd:PRK09421   8 WQAVLLSLKVSSVAVLFSLPFGILVAWLLARCRFPGKSLLDSLLHLPLVLPPVVTGYLLLISMGRRGFIGQWlyewfgiS 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  95 MLFTQKAMIFGQMVICFPVLVSMMHGALQSSDRRAVETAITLGVSIPRLAATMIWETRFP-LLAAIIAGFSRIVTEVGCS 173
Cdd:PRK09421  88 FAFSWRGAALAAAVMAFPLMVRAIRLSLEAVDRKLEQAARTLGASPWRVFFTITLPLTLPgIIAGTVLAFARSLGEFGAT 167

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 491531901 174 MMVGGNIMGVTRNIPTAI-AMESSKGAFAQgvALGIVLLSLALAL 217
Cdd:PRK09421 168 ITFVSNIPGETQTIPSAMyTLIQTPGGESA--AARLCIISIAIAL 210
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 27-215 5.79e-08

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 51.13  E-value: 5.79e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  27 VSFSVSITAISLVVLPAILMSFVLAYTDFRGKWFLLSIVNTLQAVPTVVIGLLLYMLLSRAGPWGDWQMLFTqkAMIFGQ 106
Cdd:cd06261    3 NTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGL--PALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901 107 MVICFPVLVSMMHGALQSSDRRAVETAITLGVSIPRLAATMIW-ETRFPLLAAIIAGFSRIVTEVGCSMMVGGNIMGVTR 185
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILpLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                        170       180       190
                 ....*....|....*....|....*....|
gi 491531901 186 NIPTAIAMESSKGAFAQGVALGIVLLSLAL 215
Cdd:cd06261  161 TGLLLIFAILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
TupA COG4662
ABC-type tungstate transport system, periplasmic component [Inorganic ion transport and ...
 3-231 4.05e-106

ABC-type tungstate transport system, periplasmic component [Inorganic ion transport and metabolism];


Pssm-ID: 443699 [Multi-domain]  Cd Length: 232  Bit Score: 305.49  E-value: 4.05e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901   3 LADTTLEALRLLVNFDADLWEIVAVSFSVSITAISLVVLPAILMSFVLAYTDFRGKWFLLSIVNTLQAVPTVVIGLLLYM 82
Cdd:COG4662    4 ILEGFAEALRLLLSGDPELWEIVLLSLRVSLTATLIAALIGLPLGALLALKRFPGRRLVISLLNTLMGLPPVVVGLLVYL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  83 LLSRAGPWGDWQMLFTQKAMIFGQMVICFPVLVSMMHGALQSSDRRAVETAITLGVSIPRLAATMIWETRFPLLAAIIAG 162
Cdd:COG4662   84 LLSRSGPLGFLGLLFTPTAMIIAQTVLALPIVAALTRAAVEDLDRRLRETLRSLGASRLQALLTLLWEARFGLLAAVLAG 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 491531901 163 FSRIVTEVGCSMMVGGNIMGVTRNIPTAIAMESSKGAFAQGVALGIVLLSLALALNFFLSSMRGKGYLR 231
Cdd:COG4662  164 FGRAISEVGAVMMVGGNIKGYTRVMTTAIALETSKGEFALAIALGIVLLAIALLVNALLSLLQGRGRRR 232
ABC_perm1 NF038017
ABC transporter permease; Proteins of this family are the permease subunit of an ABC ...
 28-211 3.90e-57

ABC transporter permease; Proteins of this family are the permease subunit of an ABC transporter complex, which may be involved in tungstate uptake.


Pssm-ID: 411610 [Multi-domain]  Cd Length: 184  Bit Score: 179.66  E-value: 3.90e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  28 SFSVSITAISLVVLPAILMSFVLAYTDFRGKWFLLSIVNTLQAVPTVVIGLLLYMLLSRAGPWGDWQMLFTQKAMIFGQM 107
Cdd:NF038017   1 SLRVSGTATLIAALIGIPLGALLALRRFPGRRLVISLLNTLMGLPPVVVGLIVYLLLSRSGPLGFLGLLYTPTAMIIAQA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901 108 VICFPVLVSMMHGALQSSDRRAVETAITLGVSIPRLAATMIWETRFPLLAAIIAGFSRIVTEVGCSMMVGGNIMGVTRNI 187
Cdd:NF038017  81 VLALPIVAGLTLAAVQGLDPELRLQILSLGATRWQALWTLLKEARFALLAAVLAGFGRAISEVGAVMMVGGNIRGYTRVL 160

                        170       180
                 ....*....|....*....|....
gi 491531901 188 PTAIAMESSKGAFAQGVALGIVLL 211
Cdd:NF038017 161 TTAIVLETSKGNFDLALALGIILL 184
modB PRK09421
molybdate ABC transporter permease subunit;
22-217 7.82e-20

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 84.59  E-value: 7.82e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  22 WEIVAVSFSVSITAISLVVLPAILMSFVLAYTDFRGKWFLLSIVNTLQAVPTVVIGLLLYMLLSRAGPWGDW-------Q 94
Cdd:PRK09421   8 WQAVLLSLKVSSVAVLFSLPFGILVAWLLARCRFPGKSLLDSLLHLPLVLPPVVTGYLLLISMGRRGFIGQWlyewfgiS 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  95 MLFTQKAMIFGQMVICFPVLVSMMHGALQSSDRRAVETAITLGVSIPRLAATMIWETRFP-LLAAIIAGFSRIVTEVGCS 173
Cdd:PRK09421  88 FAFSWRGAALAAAVMAFPLMVRAIRLSLEAVDRKLEQAARTLGASPWRVFFTITLPLTLPgIIAGTVLAFARSLGEFGAT 167

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 491531901 174 MMVGGNIMGVTRNIPTAI-AMESSKGAFAQgvALGIVLLSLALAL 217
Cdd:PRK09421 168 ITFVSNIPGETQTIPSAMyTLIQTPGGESA--AARLCIISIAIAL 210
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 19-217 1.26e-18

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 81.72  E-value: 1.26e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  19 ADLWEIVA---------VSFSVSITAISLVVLPAILMSFVLAYTDFRGKWFLLSIVNTLQAVPTVVIGLLLYMLLSRAGP 89
Cdd:COG0555   41 AEFWAVLTsprvlaalkLSLGTALIAALINLVFGLPLAWVLVRYRFPGKRLVDALVDLPFALPTAVAGIALLLLFGPNGW 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  90 WGDW------QMLFTQKAMIFGQMVICFPVLVSMMHGALQSSDRRAVETAITLGVSIPRLAATMIWETRFP-LLAAIIAG 162
Cdd:COG0555  121 LGQLlaplgiKVAFTPLGIVLAQTFVSLPFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPaLLTGFALA 200

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 491531901 163 FSRIVTEVGCSMMVGGNIMGVTRNIPTAIAMESSKGAFAQGVALGIVLLSLALAL 217
Cdd:COG0555  201 FARALGEFGAVIFIAGNLPMKTEILPLLIYLKLEEGDYAGATAIALVLLLISFLL 255
cysT CHL00187
sulfate transport protein; Provisional
 26-180 4.52e-11

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 60.41  E-value: 4.52e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  26 AVSFSVSITAISLVVLPAILMSFVLAYTDFRGKWFLLSIVNTLQAVPTVVIGLLLYMLLSRAGPWGDW------QMLFTQ 99
Cdd:CHL00187  58 SLTLSMALIAALINGFFGLLIAWVLVRYNFPGKRLLDAAVDLPFALPTSVAGLTLATVYGDNGWIGHLlshlgiQIVFTK 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901 100 KAMIFGQMVICFPVLVSMMHGALQSSDRRAVETAITLGVSIPRLAATMIWETRFP-LLAAIIAGFSRIVTEVGCSMMVGG 178
Cdd:CHL00187 138 LGVLLAMIFVSFPFVVRTIQPVLQEIEKELEEAAWSLGASPWQTFWKVIFPPLIPaLLTGLALTFSRAIGEYGSIVIISS 217


                 ..
gi 491531901 179 NI 180
Cdd:CHL00187 218 NI 219
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
17-227 1.44e-10

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 60.17  E-value: 1.44e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  17 FDADLWEIVAVSFSVSITAISLVVLPAILMSFVLAYTDFRGKWFLLSIVNTLQAVPTVVIGLLLYMLLSRAGPWGDWQM- 95
Cdd:COG1178   48 SDPYLWRALGNTLLLALLVTLLSLLLGVPLAWLLARTDFPGRRLLRWLLLLPLALPPYVVALAWIALFGPNGLLNTLLRa 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  96 --------LFTQKAMIFGQMVICFPVLVSMMHGALQSSDRRAVETAITLGVSIPRLAATMIWetrfPLLA-AIIAG---- 162
Cdd:COG1178  128 lfgleppdIYGLGGIILVLVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTL----PLLRpAIAAGallv 203

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 491531901 163 FSRIVTEVGCSMMVGGNImgvtRNIPTAIAME-SSKGAFAQGVALGIVLLSLALALNFFLSSMRGK 227
Cdd:COG1178  204 FLLCLADFGTPLVLGGGY----TTLTTAIYQAwLGDFDLGAAAALALVLLLLVLLLLLLERRLRRR 265
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 18-217 4.77e-10

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 57.81  E-value: 4.77e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  18 DADLWEIVAVSFSVSITAISLVVLPAILMSFVLAYTDFRGKWFLLSIVNTLQAVPTVVIGLLLYMLLSRAGpwgdwqMLF 97
Cdd:COG1177   56 DPRLLDALLNSLLIALLSTLLATVLGTPAALALARYRFRGRRLLLALLLLPLVVPGIVLGVALLLLFSALG------LSG 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  98 TQKAMIFGQMVICFPVLVSMMHGALQSSDRRAVETAITLGVSiprlAATMIWETRFPLLA-AIIAG----FSRIVTEVGC 172
Cdd:COG1177  130 GLWGLILAHVVFTLPFVVLVVLARLQGFDPSLEEAARDLGAS----PWQTFRRVTLPLIApGILAGallaFTLSFDEFVI 205

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 491531901 173 SMMVGGnimGVTRNIPTAIAMESSKGAFAQGVALGIVLLSLALAL 217
Cdd:COG1177  206 TLFLAG---PGVTTLPVYIYSMIRRGISPEINALSTLLILLSLLL 247
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
15-227 1.65e-08

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 54.01  E-value: 1.65e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  15 VNFDADLWEIVAVSFSVSITAISLVVLPAILMSFVLAYTDFRGKWFLLSIVNTLQAVPTVVIGLLLYMLLSRAGPWGDWQ 94
Cdd:COG1178  330 VLLDPSLLRALLNSLLLALLAALLAVLLALLLAYLVRRRRGRLARLLDRLAMLPYAVPGIVLGLGLLLLFNRPLPLLLYG 409

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  95 MLFtqkAMIFGQMVICFPVLVSMMHGALQSSDRRAVETAITLGVSIPRLAATMIWE-TRFPLLAAIIAGFSRIVTEVGCS 173
Cdd:COG1178  410 TLA---ILVLAYVVRFLPFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPlLRPGLLAAALLVFVTSMKELSAT 486

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 491531901 174 MMVGGNimgVTRNIPTAIAMESSKGAFAQGVALGIVLLSLALALNFFLSSMRGK 227
Cdd:COG1178  487 LLLRPP---GFETLAVLIYQLASSGRYGEAAALALLLVLVSLLPVLLLERLLGR 537
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 27-215 5.79e-08

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 51.13  E-value: 5.79e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  27 VSFSVSITAISLVVLPAILMSFVLAYTDFRGKWFLLSIVNTLQAVPTVVIGLLLYMLLSRAGPWGDWQMLFTqkAMIFGQ 106
Cdd:cd06261    3 NTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGL--PALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901 107 MVICFPVLVSMMHGALQSSDRRAVETAITLGVSIPRLAATMIW-ETRFPLLAAIIAGFSRIVTEVGCSMMVGGNIMGVTR 185
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILpLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                        170       180       190
                 ....*....|....*....|....*....|
gi 491531901 186 NIPTAIAMESSKGAFAQGVALGIVLLSLAL 215
Cdd:cd06261  161 TGLLLIFAILFPGDLGVAAAVALILLLLSL 190
cysW PRK11602
sulfate/thiosulfate ABC transporter permease CysW;
17-224 1.80e-05

sulfate/thiosulfate ABC transporter permease CysW;


Pssm-ID: 183225  Cd Length: 283  Bit Score: 44.74  E-value: 1.80e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  17 FDADLWEIVAVSFSVSITAISLVVLPAILMSFVLAYTDFRGKWFLLSIVNTLQAVPTVVIGLLLYMLLSRAGPWGDW--- 93
Cdd:PRK11602  58 ADPDMLHAIWLTVLIALIAVPVNLVFGILLAWLVTRFNFPGRQLLLTLLDIPFAVSPVVAGLVYLLFYGSNGPLGGWlde 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  94 ---QMLFTQKAMIFGQMVICFPVLVSMMHGALQSSDRRAVETAITLGVSiprlAATMIWETRFP-----LLAAIIAGFSR 165
Cdd:PRK11602 138 hnlQLMFSWPGMVLVTIFVTCPFVVRELVPVMLSQGSQEDEAAILLGAS----GWQMFRRVTLPnirwaLLYGVVLTNAR 213

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 491531901 166 IVTEVGCSMMVGGNIMGVTRNIPTAIAM----ESSKGAFAQGvalgiVLLSLALALNFFLSSM 224
Cdd:PRK11602 214 AIGEFGAVSVVSGSIRGETLSLPLQIELleqdYNTVGSFTAA-----ALLTLMAIITLFLKSM 271
PRK10971 PRK10971
sulfate/thiosulfate ABC transporter permease CysT;
44-227 2.15e-03

sulfate/thiosulfate ABC transporter permease CysT;


Pssm-ID: 182873  Cd Length: 277  Bit Score: 38.20  E-value: 2.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  44 ILMSFVLAYTDFRGKWFLLSIVNTLQAVPTVVIGLLLYMLLSRAGPWGDWQMLFTQK----------AMIFGQMvicfPV 113
Cdd:PRK10971  79 LLMAWILTRYRFPGRTLLDALMDLPFALPTAVAGLTLASLFSVNGWYGEWLAKFDIKvtytwlgiavAMAFTSI----PF 154

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901 114 LVSMMHGALQSSDRRAVETAITLGVSIPRLAATMIWETRFP-LLAAIIAGFSRIVTEVGCSMMVGGNIMGVTRNIPTAIA 192
Cdd:PRK10971 155 VVRTVQPVLEELGPEYEEAAETLGATRWQSFRKVVLPELSPaLLAGVALSFTRSLGEFGAVIFIAGNIAWKTEVTSLMIF 234

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 491531901 193 MESSKGAFAQGVALGIVLLSLALALNFFLSSMRGK 227
Cdd:PRK10971 235 VRLQEFDYPAASAIASVILAASLLLLFSINTLQSR 269
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 18-222 2.92e-03

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 37.82  E-value: 2.92e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  18 DADLWEIVAVSFSVSITAISLVVLPAILMSFVLAYTDFrGKWFLLSIVNTLQAVPTVVIGLLLYMLLSragpwgdwqmlF 97
Cdd:COG0600   56 SGELWEHLLASLLRVLLGFALAALLGVPLGLLLGLSRL-LRRLLDPLLVFLRPIPPLALAPLLILWFG-----------I 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901  98 TQKAMIFGQMVICFPVLVSMMHGALQSSDRRAVETAITLGVSiprlAATMIWETRFP-LLAAIIAGFsRIVTEVGCSMMV 176
Cdd:COG0600  124 GEASKIFVIFLGAFFPILLNTAAGVRSVDPELLELARSLGAS----RWQILRKVVLPaALPYIFTGL-RIALGLAWIGLV 198

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 491531901 177 GGNIMGVTRNIPTAIAMESSKGAFAQGVALGIVLLSLALALNFFLS 222
Cdd:COG0600  199 VAELLGASSGLGYLILDARQLLDTDLVFAAILVIGLLGLLLDLLLR 244
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 7-124 3.27e-03

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 37.77  E-value: 3.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491531901   7 TLEALRLLVNfDADLWEIVAVSFSVSITAISLVVLPAILMSFVLAYTDFRGKWFLLSIVNTLQAVPTVVIGLLLYMLLSR 86
Cdd:COG0395   59 TLENYRAAFT-DGPFGRYLLNSLIVAVVSTVLSLLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQ 137

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 491531901  87 AGpwgdwqMLFTQKAMIFGQMVICFPVLVSMMHGALQS 124
Cdd:COG0395  138 LG------LLNTYWGLILPYLAFGLPFGIFLLRQFFRS 169
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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