|
Name |
Accession |
Description |
Interval |
E-value |
| DnaB |
TIGR00665 |
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein ... |
31-470 |
0e+00 |
|
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273206 [Multi-domain] Cd Length: 432 Bit Score: 671.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 31 PPHNLAIEQAVLAALMTVAESLEQVGDVLQESDFYATRHKYIYRAIDTLAKENSPYDAVLVNDWLIKHNLLDAIGGEEYL 110
Cdd:TIGR00665 1 PPHNIEAEQAVLGAILLDNEAIDDVAEILKPEDFYRPAHRLIFQAILDLYEKGEPIDLVTVAEELEKDGELEEVGGLAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 111 MQLMADSPSSFyNLETYAAKIKEFSTLRNMIKVSSEILQNAYDTKGrTVSEILDLAETNIFQIAEqhnnNKKNAGPKAIN 190
Cdd:TIGR00665 81 AELASNVPSAA-NIEYYAEIVKEKAILRRLIQAGTEIVELAYDPTG-DVEELLDEAEQKIFEIAE----SRTSKGFKSIK 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 191 TVVADVFDKLNELSQMDGNITGLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLVESVLFNNDLPALVYSMEMP 270
Cdd:TIGR00665 155 EILKEAVEEIEELYERKGGITGVPTGFTDLDKLTSGLQPSDLIILAARPSMGKTAFALNIAENAAIKEGKPVAFFSLEMS 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 271 ADSIAMRLISSYGKVHQGNLRSGKLSGDEWSKVTGTILQLQEKHLYIDDSSALPPTEVRSRARRIAKQHGgkLGCIMVDY 350
Cdd:TIGR00665 235 AEQLVMRMLSSESRVDSQKLRTGRLSDEDWEKLTEAAGELSEAPLYIDDTPGLTITELRAKARRLKREHG--LGLIVIDY 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 351 LQLMKVPGMGDNRVGEISEISRSLKALAKEMQCPVIALSQLNRSLENRPNKRPVMSDLRESGAIEQDADLIMFIYRDEVY 430
Cdd:TIGR00665 313 LQLMSGSGRSENRQQEVSEISRSLKALAKELNVPVIALSQLSRSVEQREDKRPQLSDLRESGSIEQDADIVMFLYRDEYY 392
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 491320778 431 NKESKEAGTAEIIIGKQRNGPIGTVRLAFEGQYTRFSNLS 470
Cdd:TIGR00665 393 NPDSEDKGIAEIIIAKQRNGPTGTVKLAFLGEYTRFENLA 432
|
|
| DnaB |
COG0305 |
Replicative DNA helicase [Replication, recombination and repair]; |
34-470 |
0e+00 |
|
Replicative DNA helicase [Replication, recombination and repair];
Pssm-ID: 440074 [Multi-domain] Cd Length: 429 Bit Score: 639.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 34 NLAIEQAVLAALMTVAESLEQVGDVLQESDFYATRHKYIYRAIDTLAKENSPYDAVLVNDWLIKHNLLDAIGGEEYLMQL 113
Cdd:COG0305 1 NIEAEQAVLGALLLDNDALDEVADILKPEDFYRPAHRLIFEAILDLYERGEPIDLVTVAEELEKRGELEEVGGAAYLAEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 114 MADSPSSFyNLETYAAKIKEFSTLRNMIKVSSEILQNAYDTKgRTVSEILDLAETNIFQIAEQHNNNkknaGPKAINTVV 193
Cdd:COG0305 81 AENVPSAA-NIEYYARIVKEKALLRRLIEAGTEIVELAYDED-EDVDELLDEAEQKIFEIAEKRSSK----GFVSISDIL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 194 ADVFDKLNELSQMDGNITGLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLVESVLFNNDLPALVYSMEMPADS 273
Cdd:COG0305 155 KEALERIEELYKNGGGITGVPTGFTDLDKLTGGLQPGDLIILAARPSMGKTAFALNIARNAAIKEGKPVAIFSLEMSAEQ 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 274 IAMRLISSYGKVHQGNLRSGKLSGDEWSKVTGTILQLQEKHLYIDDSSALPPTEVRSRARRIAKQHGgkLGCIMVDYLQL 353
Cdd:COG0305 235 LVMRLLSSEARIDSSKLRTGKLSDEDWERLSSAAGELSEAPIYIDDTPGLTIAEIRAKARRLKREHG--LGLIVIDYLQL 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 354 MKVPGMGDNRVGEISEISRSLKALAKEMQCPVIALSQLNRSLENRPNKRPVMSDLRESGAIEQDADLIMFIYRDEVYNKE 433
Cdd:COG0305 313 MSGSGRSENRQQEISEISRSLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGSIEQDADVVMFLYRDEYYNPD 392
|
410 420 430
....*....|....*....|....*....|....*..
gi 491320778 434 SKEAGTAEIIIGKQRNGPIGTVRLAFEGQYTRFSNLS 470
Cdd:COG0305 393 SEDKGIAEIIIAKQRNGPTGTVKLAFDGEYTRFENLA 429
|
|
| PRK05748 |
PRK05748 |
replicative DNA helicase; Provisional |
27-474 |
0e+00 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180232 [Multi-domain] Cd Length: 448 Bit Score: 598.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 27 EFRTPPHNLAIEQAVLAALMTVAESLEQVGDVLQESDFYATRHKYIYRAIDTLAKENSPYDAVLVNDWLIKHNLLDAIGG 106
Cdd:PRK05748 6 ALRVPPQSIEAEQAVLGAIFLDPDALITVSEYLSPDDFYRHAHRLIFRAMLKLSDRGEPIDVVTVTEILDDQGDLEEVGG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 107 EEYLMQLMADSPSSfYNLETYAAKIKEFSTLRNMIKVSSEILQNAYDTKGrTVSEILDLAETNIFQIAEQHNNnkknAGP 186
Cdd:PRK05748 86 LSYLAELANSVPTA-ANIEYYAKIVAEKAMLRRLIRTATEIANDAYEPED-DADEILDEAEKKIFEVSERRNK----SGF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 187 KAINTVVADVFDKLNELSQMDGNITGLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLVESVLFNNDLPALVYS 266
Cdd:PRK05748 160 KNIKDVLVKAYDRIEMLHNQTGDITGIPTGFTDLDKMTSGLQPNDLIIVAARPSVGKTAFALNIAQNVATKTDKNVAIFS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 267 MEMPADSIAMRLISSYGKVHQGNLRSGKLSGDEWSKVTGTILQLQEKHLYIDDSSALPPTEVRSRARRIAKQHGGkLGCI 346
Cdd:PRK05748 240 LEMGAESLVMRMLCAEGNIDAQRLRTGQLTDDDWPKLTIAMGSLSDAPIYIDDTPGIKVTEIRARCRRLAQEHGG-LGLI 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 347 MVDYLQLMKVPGM-GDNRVGEISEISRSLKALAKEMQCPVIALSQLNRSLENRPNKRPVMSDLRESGAIEQDADLIMFIY 425
Cdd:PRK05748 319 LIDYLQLIQGSGRsGENRQQEVSEISRSLKALAKELKVPVIALSQLSRGVEQRQDKRPVMSDIRESGSIEQDADIVAFLY 398
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 491320778 426 RDEVYNKESKEAGTAEIIIGKQRNGPIGTVRLAFEGQYTRFSNLSPEFY 474
Cdd:PRK05748 399 RDDYYDEETENKNTIEIIIAKQRNGPVGTVELAFQKEYNKFVNLARREE 447
|
|
| dnaB_SPI-7_type |
NF040583 |
SPI-7-type island replicative DNA helicase; Members of this family are DnaB-PI, a ... |
31-469 |
1.71e-167 |
|
SPI-7-type island replicative DNA helicase; Members of this family are DnaB-PI, a pathogenicity island (PI) variant of the replicative DNA helicase DnaB. Members are found with other conjugative element replication proteins such as ParA, ParB in genetic islands whose core proteins (but not cargo proteins) are shared with the Salmonella typhi SPI-7 island.
Pssm-ID: 468557 [Multi-domain] Cd Length: 434 Bit Score: 479.12 E-value: 1.71e-167
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 31 PPHNLAIEQAVLAALMTVAESLEQVGDVLQESDFYATRHKYIYRAIDTLAKENSPYDAVLVNDWLIKHNLLDAIGGEEYL 110
Cdd:NF040583 1 GPYSVEAEQSVLGGLMLDNDRWDDVALLLAADDFYSRAHRIIFRAMARLVSAGQPIDLITLSESLEQQGQLEQVGGFAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 111 MQLMADSPSSfYNLETYAAKIKEFSTLRNMIKVSSEILQNAYDtkGRT-VSEILDLAETNIFQIAEQHNNNKknagPKAI 189
Cdd:NF040583 81 AELSKNTPSA-ANIVAYAEIVAEYSRARQLLALGHDLSADASA--PRAdIADLLEQAEQRLFDIAEQAEPQQ----EVTL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 190 NTVVADVFDKLnELSQMDGN-ITGLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLVESVLFNN-DLPALVYSM 267
Cdd:NF040583 154 IEGLETLVSEL-ELRCQSGNgITGTPTGFAELDEMTCGLQPGDLILLAARPSMGKTALALAFCLGALRGKpDKVVQIYSL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 268 EMPADSIAMRLISSYGKVHQGNLRSGKLSGDEWSKVTGTILQLQE--KHLYIDDSSALPPTEVRSRARRIAKQHGgKLGC 345
Cdd:NF040583 233 EMPTEQLLMRLVSMLGRVPLQRLRSGLLDDEDWARISQAMALLTDwkDRLIIDDTSYLTPALLRARARRNARKYG-KPSL 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 346 IMVDYLQLMKVPGMgDNRVGEISEISRSLKALAKEMQCPVIALSQLNRSLENRPNKRPVMSDLRESGAIEQDADLIMFIY 425
Cdd:NF040583 312 IMVDYLQLMRCPGQ-ENRTQEIAEISRSLKALAKEMGCPVLALSQLNRQLESRADKRPNNGDLRDSGALEQDADLIMFIY 390
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 491320778 426 RDEVYNKESKEAGTAEIIIGKQRNGPIGTVRLAFEGQYTRFSNL 469
Cdd:NF040583 391 RDEVYNPNTPDKGIAEIIIGKQRQGPTGTVKVQFDGRYTRFSDL 434
|
|
| DnaB_C |
pfam03796 |
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
212-468 |
8.90e-159 |
|
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 427509 [Multi-domain] Cd Length: 254 Bit Score: 449.94 E-value: 8.90e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 212 GLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLVESVLFNNDLPALVYSMEMPADSIAMRLISSYGKVHQGNLR 291
Cdd:pfam03796 1 GLPTGFTDLDRLTGGLQPGDLIIIAARPSMGKTAFALNIARNAAVKHKKPVAIFSLEMSAEQLVMRLLASEAGVDSQKLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 292 SGKLSGDEWSKVTGTILQLQEKHLYIDDSSALPPTEVRSRARRIAKQHGgkLGCIMVDYLQLMKVPGMGDNRVGEISEIS 371
Cdd:pfam03796 81 TGQLTDEDWEKLAKAAGRLSEAPLYIDDTPGLSIAEIRAKARRLKREHG--LGLIVIDYLQLMSGGSRGENRQQEISEIS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 372 RSLKALAKEMQCPVIALSQLNRSLENRPNKRPVMSDLRESGAIEQDADLIMFIYRDEVYNKESKEaGTAEIIIGKQRNGP 451
Cdd:pfam03796 159 RSLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGAIEQDADVVMFLYRDEYYNPKEPE-GKAEIIIAKQRNGP 237
|
250
....*....|....*..
gi 491320778 452 IGTVRLAFEGQYTRFSN 468
Cdd:pfam03796 238 TGTVKLAFLGEYTRFEN 254
|
|
| DnaB_C |
cd00984 |
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase ... |
212-468 |
2.32e-143 |
|
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 410864 [Multi-domain] Cd Length: 256 Bit Score: 410.75 E-value: 2.32e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 212 GLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLVESVLFNNDLPALVYSMEMPADSIAMRLISSYGKVHQGNLR 291
Cdd:cd00984 1 GLPTGFTDLDKLTGGLQPGDLIIIAARPSMGKTAFALNIAENIALDEGLPVLFFSLEMSAEQLAERLLSSESGVSLSKLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 292 SGKLSGDEWSKVTGTILQLQEKHLYIDDSSALPPTEVRSRARRIAKQHGGkLGCIMVDYLQLMKVPGMGDNRVGEISEIS 371
Cdd:cd00984 81 TGRLDDEDWERLTAAMGELSELPLYIDDTPGLTVDEIRAKARRLKREHGG-LGLIVIDYLQLIRGSKRAENRQQEVAEIS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 372 RSLKALAKEMQCPVIALSQLNRSLENRPNKRPVMSDLRESGAIEQDADLIMFIYRDEVYNKESKEAGTAEIIIGKQRNGP 451
Cdd:cd00984 160 RSLKALAKELNVPVIALSQLNRGVESRTDKRPMLSDLRESGSIEQDADVVIFLYRDEYYDKDSEDKGIAEIIIAKNRNGP 239
|
250
....*....|....*..
gi 491320778 452 IGTVRLAFEGQYTRFSN 468
Cdd:cd00984 240 TGTVYLAFNPEYTRFTD 256
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| DnaB |
TIGR00665 |
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein ... |
31-470 |
0e+00 |
|
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273206 [Multi-domain] Cd Length: 432 Bit Score: 671.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 31 PPHNLAIEQAVLAALMTVAESLEQVGDVLQESDFYATRHKYIYRAIDTLAKENSPYDAVLVNDWLIKHNLLDAIGGEEYL 110
Cdd:TIGR00665 1 PPHNIEAEQAVLGAILLDNEAIDDVAEILKPEDFYRPAHRLIFQAILDLYEKGEPIDLVTVAEELEKDGELEEVGGLAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 111 MQLMADSPSSFyNLETYAAKIKEFSTLRNMIKVSSEILQNAYDTKGrTVSEILDLAETNIFQIAEqhnnNKKNAGPKAIN 190
Cdd:TIGR00665 81 AELASNVPSAA-NIEYYAEIVKEKAILRRLIQAGTEIVELAYDPTG-DVEELLDEAEQKIFEIAE----SRTSKGFKSIK 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 191 TVVADVFDKLNELSQMDGNITGLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLVESVLFNNDLPALVYSMEMP 270
Cdd:TIGR00665 155 EILKEAVEEIEELYERKGGITGVPTGFTDLDKLTSGLQPSDLIILAARPSMGKTAFALNIAENAAIKEGKPVAFFSLEMS 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 271 ADSIAMRLISSYGKVHQGNLRSGKLSGDEWSKVTGTILQLQEKHLYIDDSSALPPTEVRSRARRIAKQHGgkLGCIMVDY 350
Cdd:TIGR00665 235 AEQLVMRMLSSESRVDSQKLRTGRLSDEDWEKLTEAAGELSEAPLYIDDTPGLTITELRAKARRLKREHG--LGLIVIDY 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 351 LQLMKVPGMGDNRVGEISEISRSLKALAKEMQCPVIALSQLNRSLENRPNKRPVMSDLRESGAIEQDADLIMFIYRDEVY 430
Cdd:TIGR00665 313 LQLMSGSGRSENRQQEVSEISRSLKALAKELNVPVIALSQLSRSVEQREDKRPQLSDLRESGSIEQDADIVMFLYRDEYY 392
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 491320778 431 NKESKEAGTAEIIIGKQRNGPIGTVRLAFEGQYTRFSNLS 470
Cdd:TIGR00665 393 NPDSEDKGIAEIIIAKQRNGPTGTVKLAFLGEYTRFENLA 432
|
|
| DnaB |
COG0305 |
Replicative DNA helicase [Replication, recombination and repair]; |
34-470 |
0e+00 |
|
Replicative DNA helicase [Replication, recombination and repair];
Pssm-ID: 440074 [Multi-domain] Cd Length: 429 Bit Score: 639.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 34 NLAIEQAVLAALMTVAESLEQVGDVLQESDFYATRHKYIYRAIDTLAKENSPYDAVLVNDWLIKHNLLDAIGGEEYLMQL 113
Cdd:COG0305 1 NIEAEQAVLGALLLDNDALDEVADILKPEDFYRPAHRLIFEAILDLYERGEPIDLVTVAEELEKRGELEEVGGAAYLAEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 114 MADSPSSFyNLETYAAKIKEFSTLRNMIKVSSEILQNAYDTKgRTVSEILDLAETNIFQIAEQHNNNkknaGPKAINTVV 193
Cdd:COG0305 81 AENVPSAA-NIEYYARIVKEKALLRRLIEAGTEIVELAYDED-EDVDELLDEAEQKIFEIAEKRSSK----GFVSISDIL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 194 ADVFDKLNELSQMDGNITGLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLVESVLFNNDLPALVYSMEMPADS 273
Cdd:COG0305 155 KEALERIEELYKNGGGITGVPTGFTDLDKLTGGLQPGDLIILAARPSMGKTAFALNIARNAAIKEGKPVAIFSLEMSAEQ 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 274 IAMRLISSYGKVHQGNLRSGKLSGDEWSKVTGTILQLQEKHLYIDDSSALPPTEVRSRARRIAKQHGgkLGCIMVDYLQL 353
Cdd:COG0305 235 LVMRLLSSEARIDSSKLRTGKLSDEDWERLSSAAGELSEAPIYIDDTPGLTIAEIRAKARRLKREHG--LGLIVIDYLQL 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 354 MKVPGMGDNRVGEISEISRSLKALAKEMQCPVIALSQLNRSLENRPNKRPVMSDLRESGAIEQDADLIMFIYRDEVYNKE 433
Cdd:COG0305 313 MSGSGRSENRQQEISEISRSLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGSIEQDADVVMFLYRDEYYNPD 392
|
410 420 430
....*....|....*....|....*....|....*..
gi 491320778 434 SKEAGTAEIIIGKQRNGPIGTVRLAFEGQYTRFSNLS 470
Cdd:COG0305 393 SEDKGIAEIIIAKQRNGPTGTVKLAFDGEYTRFENLA 429
|
|
| PRK05748 |
PRK05748 |
replicative DNA helicase; Provisional |
27-474 |
0e+00 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180232 [Multi-domain] Cd Length: 448 Bit Score: 598.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 27 EFRTPPHNLAIEQAVLAALMTVAESLEQVGDVLQESDFYATRHKYIYRAIDTLAKENSPYDAVLVNDWLIKHNLLDAIGG 106
Cdd:PRK05748 6 ALRVPPQSIEAEQAVLGAIFLDPDALITVSEYLSPDDFYRHAHRLIFRAMLKLSDRGEPIDVVTVTEILDDQGDLEEVGG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 107 EEYLMQLMADSPSSfYNLETYAAKIKEFSTLRNMIKVSSEILQNAYDTKGrTVSEILDLAETNIFQIAEQHNNnkknAGP 186
Cdd:PRK05748 86 LSYLAELANSVPTA-ANIEYYAKIVAEKAMLRRLIRTATEIANDAYEPED-DADEILDEAEKKIFEVSERRNK----SGF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 187 KAINTVVADVFDKLNELSQMDGNITGLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLVESVLFNNDLPALVYS 266
Cdd:PRK05748 160 KNIKDVLVKAYDRIEMLHNQTGDITGIPTGFTDLDKMTSGLQPNDLIIVAARPSVGKTAFALNIAQNVATKTDKNVAIFS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 267 MEMPADSIAMRLISSYGKVHQGNLRSGKLSGDEWSKVTGTILQLQEKHLYIDDSSALPPTEVRSRARRIAKQHGGkLGCI 346
Cdd:PRK05748 240 LEMGAESLVMRMLCAEGNIDAQRLRTGQLTDDDWPKLTIAMGSLSDAPIYIDDTPGIKVTEIRARCRRLAQEHGG-LGLI 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 347 MVDYLQLMKVPGM-GDNRVGEISEISRSLKALAKEMQCPVIALSQLNRSLENRPNKRPVMSDLRESGAIEQDADLIMFIY 425
Cdd:PRK05748 319 LIDYLQLIQGSGRsGENRQQEVSEISRSLKALAKELKVPVIALSQLSRGVEQRQDKRPVMSDIRESGSIEQDADIVAFLY 398
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 491320778 426 RDEVYNKESKEAGTAEIIIGKQRNGPIGTVRLAFEGQYTRFSNLSPEFY 474
Cdd:PRK05748 399 RDDYYDEETENKNTIEIIIAKQRNGPVGTVELAFQKEYNKFVNLARREE 447
|
|
| PRK08006 |
PRK08006 |
replicative DNA helicase DnaB; |
5-480 |
0e+00 |
|
replicative DNA helicase DnaB;
Pssm-ID: 181193 [Multi-domain] Cd Length: 471 Bit Score: 515.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 5 LANTKPTPVKTESSSNDSGALKEFRTPPHNLAIEQAVLAALMTVAESLEQVGDVLQESDFYATRHKYIYRAIDTLAKENS 84
Cdd:PRK08006 1 MAGNKPFNKQQAEPRERDPQVAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 85 PYDAVLVNDWLIKHNLLDAIGGEEYLMQLMADSPSSfYNLETYAAKIKEFSTLRNMIKVSSEILQNAYDTKGRTVSEILD 164
Cdd:PRK08006 81 PIDLITLAESLERQGQLDSVGGFAYLAELSKNTPSA-ANISAYADIVRERAVVREMISVANEIADAGYDPQGRTSEDLLD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 165 LAETNIFQIAEqhNNNKKNAGPKAINTVVADVFDKLNELSQM--DGnITGLTTGFVELDNKTSGMQAGDLIIVAARPSMG 242
Cdd:PRK08006 160 LAESRVFQIAE--SRANKDEGPKNIADILDATVARIEQLFQQphDG-VTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMG 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 243 KTTFAMNLVESVLFNNDLPALVYSMEMPADSIAMRLISSYGKVHQGNLRSGKLSGDEWSKVTGTI-LQLQEKHLYIDDSS 321
Cdd:PRK08006 237 KTTFAMNLCENAAMLQDKPVLIFSLEMPGEQIMMRMLASLSRVDQTRIRTGQLDDEDWARISGTMgILLEKRNMYIDDSS 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 322 ALPPTEVRSRARRIAKQHGGkLGCIMVDYLQLMKVPGMGDNRVGEISEISRSLKALAKEMQCPVIALSQLNRSLENRPNK 401
Cdd:PRK08006 317 GLTPTEVRSRARRIFREHGG-LSLIMIDYLQLMRVPSLSDNRTLEIAEISRSLKALAKELQVPVVALSQLNRSLEQRADK 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 402 RPVMSDLRESGAIEQDADLIMFIYRDEVYNKESKEAGTAEIIIGKQRNGPIGTVRLAFEGQYTRFSNlspefYA--QYDD 479
Cdd:PRK08006 396 RPVNSDLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDN-----YAgpQYDD 470
|
.
gi 491320778 480 D 480
Cdd:PRK08006 471 E 471
|
|
| PRK08840 |
PRK08840 |
replicative DNA helicase; Provisional |
29-481 |
3.69e-180 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181562 [Multi-domain] Cd Length: 464 Bit Score: 512.61 E-value: 3.69e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 29 RTPPHNLAIEQAVLAALMTVAESLEQVGDVLQESDFYATRHKYIYRAIDTLAKENSPYDAVLVNDWLIKHNLLDAIGGEE 108
Cdd:PRK08840 18 KVPPHSLEAEQSVIGGLLLDNERWDTVAEKVVASDFYSRPHRLIFEGVKSILEAGKPLDLITLSEHLERREQLEDVGGFA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 109 YLMQLMADSPSSfYNLETYAAKIKEFSTLRNMIKVSSEILQNAYDTKGRTVSEILDLAETNIFQIAEQHNNnkKNAGPKA 188
Cdd:PRK08840 98 YLADLAKNTPSA-ANINAYADIVAERALVRNLIGVANEIADAGYDPQGRTSEDLLDMAESKVFAIAEARTS--ENEGPQN 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 189 INTVVADVFDKLNEL--SQMDGnITGLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLVESVLFNNDLPALVYS 266
Cdd:PRK08840 175 VDSILEKTLERIELLykTPQDG-VTGVDTGFTDLNKKTAGLQGSDLIIVAARPSMGKTTFAMNLCENAAMDQDKPVLIFS 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 267 MEMPADSIAMRLISSYGKVHQGNLRSGKLSGDEWSKVTGTI-LQLQEKHLYIDDSSALPPTEVRSRARRIAKQHGGkLGC 345
Cdd:PRK08840 254 LEMPAEQLMMRMLASLSRVDQTKIRTGQLDDEDWARISSTMgILMEKKNMYIDDSSGLTPTEVRSRARRIAREHGG-LSM 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 346 IMVDYLQLMKVPGMGDNRVGEISEISRSLKALAKEMQCPVIALSQLNRSLENRPNKRPVMSDLRESGAIEQDADLIMFIY 425
Cdd:PRK08840 333 IMVDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIY 412
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 491320778 426 RDEVYNKESKEAGTAEIIIGKQRNGPIGTVRLAFEGQYTRFSNLS-PEFyaqydDDE 481
Cdd:PRK08840 413 RDEVYNPDSPLKGTAEIIIGKQRNGPIGSVRLTFQGQYSRFDNYAgPAF-----DDE 464
|
|
| PRK06904 |
PRK06904 |
replicative DNA helicase; Validated |
31-477 |
2.00e-178 |
|
replicative DNA helicase; Validated
Pssm-ID: 136106 [Multi-domain] Cd Length: 472 Bit Score: 508.38 E-value: 2.00e-178
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 31 PPHNLAIEQAVLAALMTVAESLEQVGDVLQESDFYATRHKYIYRAIDTLAKENSPYDAVLVNDWLIKHNLLDAIGGEEYL 110
Cdd:PRK06904 23 PPHSIEAEQAVLGGIMLDNRHWDSVAERVIADDFYTFEHRIIFQEMELLFRQNTPIDLLTLDQALKTKGKSDEVGGFAYL 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 111 MQLMADSPSSFyNLETYAAKIKEFSTLRNMIKVSSEILQNAYDTKGRTVSEILDLAETNIFQIAEQHNNnkKNAGPKAIN 190
Cdd:PRK06904 103 AELSNNTPSAA-NILAYADIVREKAILRELISVGNNIAKNAYSPKGQDIKDILDEAERDVFSIAEKRTT--ANEGPQNVI 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 191 TVVADVFDKLNELSQMDGN--ITGLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLVESVLFNNDLPALVYSME 268
Cdd:PRK06904 180 NLLENTIDKIENLAATPTNngVTGVTTGFTDLDKKTAGLQPSDLIIVAARPSMGKTTFAMNLCENAAMASEKPVLVFSLE 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 269 MPADSIAMRLISSYGKVHQGNLRSGK-LSGDEWSKVTGTILQLQEK-HLYIDDSSALPPTEVRSRARRIAKQHGGkLGCI 346
Cdd:PRK06904 260 MPAEQIMMRMLASLSRVDQTKIRTGQnLDQQDWAKISSTVGMFKQKpNLYIDDSSGLTPTELRSRARRVYRENGG-LSLI 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 347 MVDYLQLMKVPGMGDNRVGEISEISRSLKALAKEMQCPVIALSQLNRSLENRPNKRPVMSDLRESGAIEQDADLIMFIYR 426
Cdd:PRK06904 339 MVDYLQLMRAPGFEDNRTLEIAEISRSLKALAKELKVPVVALSQLNRTLENRGDKRPVNSDLRESGSIEQDADLIMFIYR 418
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 491320778 427 DEVYNKESKE-AGTAEIIIGKQRNGPIGTVRLAFEGQYTRFSNL--SPEFYAQY 477
Cdd:PRK06904 419 DEVYNETTEDnKGVAEIIIGKQRNGPIGRVRLAFQGQYSRFDNLanIPQYYDKY 472
|
|
| PRK07004 |
PRK07004 |
replicative DNA helicase; Provisional |
25-474 |
4.07e-175 |
|
replicative DNA helicase; Provisional
Pssm-ID: 235907 [Multi-domain] Cd Length: 460 Bit Score: 499.82 E-value: 4.07e-175
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 25 LKEFRTPPHNLAIEQAVLAALMTVAESLEQVGDVLQESDFYATRHKYIYRAIDTLAKENSPYDAVLVNDWLIKHNLLDAI 104
Cdd:PRK07004 9 LESLKVPPHSIEAEQSVLGGLLLDNAAWDRIADFLSQSDFYRYDHRIIFEHIGRLIAATRPADVITVYEALTTSGKAEEV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 105 GGEEYLMQLMADSPSSfYNLETYAAKIKEFSTLRNMIKVSSEILQNAYDTKGRTVSEILDLAETNIFQIAEQhnNNKKNA 184
Cdd:PRK07004 89 GGLAYLNALAQNTPSA-ANIRRYAEIVRDRAVLRRLVSVADEISADAFNPQGKEVRQLLDEAESKVFSIAEE--GARGTQ 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 185 GPKAINTVVADVFDKLNELSQMDG--NITGLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLVESVLFNNDLPA 262
Cdd:PRK07004 166 GFLEIGPLLTQVVERIDTLYHTANpsDVTGTPTGFVDLDRMTSGMHGGELIIVAGRPSMGKTAFSMNIGEYVAVEYGLPV 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 263 LVYSMEMPADSIAMRLISSYGKVHQGNLRSGKLSGDEWSKVTGTILQLQEKHLYIDDSSALPPTEVRSRARRIAKQhGGK 342
Cdd:PRK07004 246 AVFSMEMPGTQLAMRMLGSVGRLDQHRMRTGRLTDEDWPKLTHAVQKMSEAQLFIDETGGLNPMELRSRARRLARQ-CGK 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 343 LGCIMVDYLQLMKVPGMGDNRVGEISEISRSLKALAKEMQCPVIALSQLNRSLENRPNKRPVMSDLRESGAIEQDADLIM 422
Cdd:PRK07004 325 LGLIIIDYLQLMSGSSQGENRATEISEISRSLKSLAKELDVPVIALSQLNRGLEQRPNKRPVMSDLRESGAIEQDADVIL 404
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 491320778 423 FIYRDEVYNKESKEAGTAEIIIGKQRNGPIGTVRLAFEGQYTRFSNLS--PEFY 474
Cdd:PRK07004 405 FIYRDEVYNPDSPDKGTAEIIIGKQRNGPIGPVRLTFLGQYTKFDNFAgaQNFY 458
|
|
| dnaB_SPI-7_type |
NF040583 |
SPI-7-type island replicative DNA helicase; Members of this family are DnaB-PI, a ... |
31-469 |
1.71e-167 |
|
SPI-7-type island replicative DNA helicase; Members of this family are DnaB-PI, a pathogenicity island (PI) variant of the replicative DNA helicase DnaB. Members are found with other conjugative element replication proteins such as ParA, ParB in genetic islands whose core proteins (but not cargo proteins) are shared with the Salmonella typhi SPI-7 island.
Pssm-ID: 468557 [Multi-domain] Cd Length: 434 Bit Score: 479.12 E-value: 1.71e-167
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 31 PPHNLAIEQAVLAALMTVAESLEQVGDVLQESDFYATRHKYIYRAIDTLAKENSPYDAVLVNDWLIKHNLLDAIGGEEYL 110
Cdd:NF040583 1 GPYSVEAEQSVLGGLMLDNDRWDDVALLLAADDFYSRAHRIIFRAMARLVSAGQPIDLITLSESLEQQGQLEQVGGFAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 111 MQLMADSPSSfYNLETYAAKIKEFSTLRNMIKVSSEILQNAYDtkGRT-VSEILDLAETNIFQIAEQHNNNKknagPKAI 189
Cdd:NF040583 81 AELSKNTPSA-ANIVAYAEIVAEYSRARQLLALGHDLSADASA--PRAdIADLLEQAEQRLFDIAEQAEPQQ----EVTL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 190 NTVVADVFDKLnELSQMDGN-ITGLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLVESVLFNN-DLPALVYSM 267
Cdd:NF040583 154 IEGLETLVSEL-ELRCQSGNgITGTPTGFAELDEMTCGLQPGDLILLAARPSMGKTALALAFCLGALRGKpDKVVQIYSL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 268 EMPADSIAMRLISSYGKVHQGNLRSGKLSGDEWSKVTGTILQLQE--KHLYIDDSSALPPTEVRSRARRIAKQHGgKLGC 345
Cdd:NF040583 233 EMPTEQLLMRLVSMLGRVPLQRLRSGLLDDEDWARISQAMALLTDwkDRLIIDDTSYLTPALLRARARRNARKYG-KPSL 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 346 IMVDYLQLMKVPGMgDNRVGEISEISRSLKALAKEMQCPVIALSQLNRSLENRPNKRPVMSDLRESGAIEQDADLIMFIY 425
Cdd:NF040583 312 IMVDYLQLMRCPGQ-ENRTQEIAEISRSLKALAKEMGCPVLALSQLNRQLESRADKRPNNGDLRDSGALEQDADLIMFIY 390
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 491320778 426 RDEVYNKESKEAGTAEIIIGKQRNGPIGTVRLAFEGQYTRFSNL 469
Cdd:NF040583 391 RDEVYNPNTPDKGIAEIIIGKQRQGPTGTVKVQFDGRYTRFSDL 434
|
|
| PRK08760 |
PRK08760 |
replicative DNA helicase; Provisional |
21-470 |
5.69e-165 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181547 [Multi-domain] Cd Length: 476 Bit Score: 474.40 E-value: 5.69e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 21 DSGALKEFRTPPHNLAIEQAVLAALMTVAESLEQVGDVLQESDFYATRHKYIYRAIDTLAKENSPYDAVLVNDWLIKHNL 100
Cdd:PRK08760 23 PEPRLDQLRVPPHSVEAEQAVLGGLMLAPDALDRVNDQLTENDFYRRDHRLIYRAIRELSEKDRPFDAVTLGEWFESQGK 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 101 LDAIGGEEYLMQLMADSPSSfYNLETYAAKIKEFSTLRNMIKVSSEILQNAYDTKGRTVSEILDLAETNIFQIAEQHNNN 180
Cdd:PRK08760 103 LEQVGDGAYLIELASTTPSA-ANIAAYAEIVRDKAVLRQLIEVGTTIVNDGFQPEGRESIELLASAEKAVFKIAEAGARG 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 181 KKNAgpKAINTVVADVFDKLNELSQMDGNITGLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLVESVLFNNDL 260
Cdd:PRK08760 182 RTDF--VAMPGALKDAFEELRNRFENGGNITGLPTGYNDFDAMTAGLQPTDLIILAARPAMGKTTFALNIAEYAAIKSKK 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 261 PALVYSMEMPADSIAMRLISSYGKVHQGNLRSGKLSGDEWSKVTGTILQLQEKHLYIDDSSALPPTEVRSRARRIAKQHg 340
Cdd:PRK08760 260 GVAVFSMEMSASQLAMRLISSNGRINAQRLRTGALEDEDWARVTGAIKMLKETKIFIDDTPGVSPEVLRSKCRRLKREH- 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 341 gKLGCIMVDYLQLMKVPGMGDNRVGEISEISRSLKALAKEMQCPVIALSQLNRSLENRPNKRPVMSDLRESGAIEQDADL 420
Cdd:PRK08760 339 -DLGLIVIDYLQLMSVPGNSENRATEISEISRSLKGLAKELNVPVIALSQLNRSLETRTDKRPVMADLRESGAIEQDADM 417
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 491320778 421 IMFIYRDEVYNKE-SKEAGTAEIIIGKQRNGPIGTVRLAFEGQYTRFSNLS 470
Cdd:PRK08760 418 IVFIYRDDYYNKEnSPDKGLAEIIIGKHRGGPTGSCKLKFFGEYTRFDNLA 468
|
|
| DnaB_C |
pfam03796 |
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
212-468 |
8.90e-159 |
|
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 427509 [Multi-domain] Cd Length: 254 Bit Score: 449.94 E-value: 8.90e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 212 GLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLVESVLFNNDLPALVYSMEMPADSIAMRLISSYGKVHQGNLR 291
Cdd:pfam03796 1 GLPTGFTDLDRLTGGLQPGDLIIIAARPSMGKTAFALNIARNAAVKHKKPVAIFSLEMSAEQLVMRLLASEAGVDSQKLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 292 SGKLSGDEWSKVTGTILQLQEKHLYIDDSSALPPTEVRSRARRIAKQHGgkLGCIMVDYLQLMKVPGMGDNRVGEISEIS 371
Cdd:pfam03796 81 TGQLTDEDWEKLAKAAGRLSEAPLYIDDTPGLSIAEIRAKARRLKREHG--LGLIVIDYLQLMSGGSRGENRQQEISEIS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 372 RSLKALAKEMQCPVIALSQLNRSLENRPNKRPVMSDLRESGAIEQDADLIMFIYRDEVYNKESKEaGTAEIIIGKQRNGP 451
Cdd:pfam03796 159 RSLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGAIEQDADVVMFLYRDEYYNPKEPE-GKAEIIIAKQRNGP 237
|
250
....*....|....*..
gi 491320778 452 IGTVRLAFEGQYTRFSN 468
Cdd:pfam03796 238 TGTVKLAFLGEYTRFEN 254
|
|
| PRK09165 |
PRK09165 |
replicative DNA helicase; Provisional |
17-478 |
3.82e-144 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181676 [Multi-domain] Cd Length: 497 Bit Score: 421.98 E-value: 3.82e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 17 SSSNDSGALKEFRTPPHNLAIEQAVLAALMTVAESLEQVGDVLQESDFYATRHKYIYRAIDTLAKENSPYDAVLVNDWLI 96
Cdd:PRK09165 7 LDLAPDAAEPEIRELPHNIEAEQALLGAILINNRALDRVSDFLKPEHFFEPLHQRIYEAIAKIIRKGKLATPVTLKTFLE 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 97 KHNLLDAIGGEEYLMQLMADSPSSFyNLETYAAKIKEFSTLRNMIKVSSEILQNAYDT-KGRTVSEILDLAETNIFQIAE 175
Cdd:PRK09165 87 NDEALGELGGVQYLAKLATEAVTII-NARDYGRIIYDLALRRELINIGEDVVNNAYDApVDVAPQEQIEDAEQKLYELAE 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 176 QHNNNKknaGPKAINTVVADVFDKLNELSQMDGNITGLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLV---- 251
Cdd:PRK09165 166 TGRYEG---GFQSFGTAITEAVDMANAAFKRDGHLSGISTGLRDLDSKLGGLHPSDLIILAGRPSMGKTALATNIAfnaa 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 252 ----------ESVLFNNDLPALVYSMEMPADSIAMRLISSYGKVHQGNLRSGKLSGDEWSKVTGTILQLQEKHLYIDDSS 321
Cdd:PRK09165 243 kayrreaqpdGSKKAVNGGVVGFFSLEMSAEQLATRILSEQSEISSSKIRRGKISEEDFEKLVDASQELQKLPLYIDDTP 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 322 ALPPTEVRSRARRIAKQHGgkLGCIMVDYLQLMKVPG--MGDNRVGEISEISRSLKALAKEMQCPVIALSQLNRSLENRP 399
Cdd:PRK09165 323 ALSISQLRARARRLKRQHG--LDLLVVDYLQLIRGSSkrSSDNRVQEISEITQGLKALAKELNIPVIALSQLSRQVEQRD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 400 NKRPVMSDLRESGAIEQDADLIMFIYRDEVY--NKESKEA---------------GTAEIIIGKQRNGPIGTVRLAFEGQ 462
Cdd:PRK09165 401 DKRPQLSDLRESGSIEQDADVVMFVYREEYYlkRKEPREGtpkheewqekmekvhNKAEVIIAKQRHGPTGTVKLAFESE 480
|
490
....*....|....*.
gi 491320778 463 YTRFSNLSPEFYAQYD 478
Cdd:PRK09165 481 FTRFGDLADRSQLPEE 496
|
|
| DnaB_C |
cd00984 |
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase ... |
212-468 |
2.32e-143 |
|
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 410864 [Multi-domain] Cd Length: 256 Bit Score: 410.75 E-value: 2.32e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 212 GLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLVESVLFNNDLPALVYSMEMPADSIAMRLISSYGKVHQGNLR 291
Cdd:cd00984 1 GLPTGFTDLDKLTGGLQPGDLIIIAARPSMGKTAFALNIAENIALDEGLPVLFFSLEMSAEQLAERLLSSESGVSLSKLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 292 SGKLSGDEWSKVTGTILQLQEKHLYIDDSSALPPTEVRSRARRIAKQHGGkLGCIMVDYLQLMKVPGMGDNRVGEISEIS 371
Cdd:cd00984 81 TGRLDDEDWERLTAAMGELSELPLYIDDTPGLTVDEIRAKARRLKREHGG-LGLIVIDYLQLIRGSKRAENRQQEVAEIS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 372 RSLKALAKEMQCPVIALSQLNRSLENRPNKRPVMSDLRESGAIEQDADLIMFIYRDEVYNKESKEAGTAEIIIGKQRNGP 451
Cdd:cd00984 160 RSLKALAKELNVPVIALSQLNRGVESRTDKRPMLSDLRESGSIEQDADVVIFLYRDEYYDKDSEDKGIAEIIIAKNRNGP 239
|
250
....*....|....*..
gi 491320778 452 IGTVRLAFEGQYTRFSN 468
Cdd:cd00984 240 TGTVYLAFNPEYTRFTD 256
|
|
| PRK05595 |
PRK05595 |
replicative DNA helicase; Provisional |
29-471 |
1.26e-139 |
|
replicative DNA helicase; Provisional
Pssm-ID: 235525 [Multi-domain] Cd Length: 444 Bit Score: 408.83 E-value: 1.26e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 29 RTPPHNLAIEQAVLAALMTVAESLEQVGDVLQESDFYATRHKYIYRAIDTLAKENSPYDAVLVNDWLIKHNLLDAIGGEE 108
Cdd:PRK05595 6 RSLPQSIEAEQSVLGAMIIDKTSIAEAAEVLKSEDFYRDSHKVIFSAIIELYQKDIAVDMLTLTENLKSTDKLEAAGGVT 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 109 YLMQLMADSPSSfYNLETYAAKIKEFSTLRNMIKVSSEILQNAYdTKGRTVSEILDLAETNIFQIAEqhnnNKKNAGPKA 188
Cdd:PRK05595 86 YITELSNSIVST-ANIQSYIKIVKDKSTLRRLIKSSTEIIENSY-NNQDDVEKVIDSAEKKIFDISE----KRTTSDFEP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 189 INTVVADVFDKLNELSQMDGNITGLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLVESVLFNNDLPALVYSME 268
Cdd:PRK05595 160 LSNVLERGFEQIENLFNNKGETTGVASGFRELDAKTSGFQKGDMILIAARPSMGKTTFALNIAEYAALREGKSVAIFSLE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 269 MPADSIAMRLISSYGKVHQGNLRSGKLSGDEWSKVTGTILQLQEKHLYIDDSSALPPTEVRSRARRIAKQHGGKLgcIMV 348
Cdd:PRK05595 240 MSKEQLAYKLLCSEANVDMLRLRTGNLEDKDWENIARASGPLAAAKIFIDDTAGVSVMEMRSKCRRLKIEHGIDM--ILI 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 349 DYLQLMKVPGMGDNRVGEISEISRSLKALAKEMQCPVIALSQLNRSLENRPNKRPVMSDLRESGAIEQDADLIMFIYRDE 428
Cdd:PRK05595 318 DYLQLMSGGKGSESRQQEVSEISRSIKALAKEMECPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRDE 397
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 491320778 429 VYNKESKEAGTAEIIIGKQRNGPIGTVRLAFEGQYTRFSNLSP 471
Cdd:PRK05595 398 YYNKETEDKNVAECIIAKQRNGPTGTVKLAWLGQYSKFGNLDV 440
|
|
| PRK08506 |
PRK08506 |
replicative DNA helicase; Provisional |
33-466 |
3.49e-136 |
|
replicative DNA helicase; Provisional
Pssm-ID: 236278 [Multi-domain] Cd Length: 472 Bit Score: 400.93 E-value: 3.49e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 33 HNLAIEQAVLAALMTVAESLEQVGDVLQESDFYATRHKYIYRAIDTLAKENSPYDAVLVNDWLIKHNLLDaiggEEYLMQ 112
Cdd:PRK08506 5 YDLDIERAVLSSILFSPDKFEEIASVLEPKDFYLPAHQDIFEAMLKLHNEDEPIDEEFIRKKLPKDKKID----EEILLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 113 LMADSPSSfyNLETYAAKIKEFSTLRNMIKVSSEILQNAYDtKGRTVSEILDLAETNIFQIAEQHNNNkknaGPKAINTV 192
Cdd:PRK08506 81 ILATNPID--NIEAYVEEIKEKSIKRELLSLANTIPEQAVE-EDQKSSDILDEVERELYSITNGSNSE----DFKDSKEV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 193 VADVFDKLNELSQMdGN--ITGLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLVESVLfNNDLPALVYSMEMP 270
Cdd:PRK08506 154 IESTMEHIKKQKRL-GNkdIIGLDTGFVELNKMTKGFNKGDLIIIAARPSMGKTTLCLNMALKAL-NQDKGVAFFSLEMP 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 271 ADSIAMRLISSYGKVHQGNLRSGKLSGDEWSKVTGTILQLQEKHLYIDDSSALPPTEVRSRARRIAKQHGgKLGCIMVDY 350
Cdd:PRK08506 232 AEQLMLRMLSAKTSIPLQNLRTGDLDDDEWERLSDACDELSKKKLFVYDSGYVNIHQVRAQLRKLKSQHP-EIGLAVIDY 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 351 LQLMKVPGMGDNRVGEISEISRSLKALAKEMQCPVIALSQLNRSLENRPNKRPVMSDLRESGAIEQDADLIMFIYRDEVY 430
Cdd:PRK08506 311 LQLMSGSGNFKDRHLQISEISRGLKLLARELDIPIIALSQLNRSLESRADKRPMLSDLRESGAIEQDADIILFVYRDDVY 390
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 491320778 431 N--------KESKEAG--------------TAEIIIGKQRNGPIGTVRLAFEGQYTRF 466
Cdd:PRK08506 391 KereekekeKKAKKEGkeerrihfqnksieEAEIIIGKNRNGPTGTVKLRFQKEFTRF 448
|
|
| phage_DnaB |
TIGR03600 |
phage replicative helicase, DnaB family, HK022 subfamily; Members of this family are phage (or ... |
34-459 |
6.87e-131 |
|
phage replicative helicase, DnaB family, HK022 subfamily; Members of this family are phage (or prophage-region) homologs of the bacterial homohexameric replicative helicase DnaB. Some phage may rely on host DnaB, while others encode their own verions. This model describes the largest phage-specific clade among the close homologs of DnaB, but there are, or course, other DnaB homologs from phage that fall outside the scope of this model. [Mobile and extrachromosomal element functions, Prophage functions]
Pssm-ID: 274672 [Multi-domain] Cd Length: 420 Bit Score: 385.60 E-value: 6.87e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 34 NLAIEQAVLAALMTVAESLEQVGDVLQESDFYATRHKYIYRAIDTLAKENSPYDAVLVNDWLIKHNLLDAIGGEEYLMQL 113
Cdd:TIGR03600 1 SIEAEQAVLGGLLLDNDFIERVMAILKPEHFYSQDHRIIFEAMLDMFAENRPVDPLTLADKLEAEGEAEKVGGLAYLAEI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 114 MADSPSSfYNLETYAAKIKEFSTLRNMIKVSSEILQNAYDTKGRTVSEILDLAETNIFQIaeqhnnNKKNA---GPKAIN 190
Cdd:TIGR03600 81 SNNTPSA-ANISSYARIVREKAKERKLIAACQRIITLACSPDGGTAEQKVEEAQAALLAL------TMSDGqedGFVTFG 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 191 TVVADVFDKLNELSQMDGNITGLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLVESVLFNNDLPALVYSMEMP 270
Cdd:TIGR03600 154 EVLEDVVRDLDKRFNPKGELTGLSTGLPKLDRLTNGLVKGDLIVIGARPSMGKTTLALNIAENVALREGKPVLFFSLEMS 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 271 ADSIAMRLISSYGKVHQGNLRSGKLSGDEWSKVTGTILQLQEKHLYIDDSSALPPTEVRSRARRIAKQHGGkLGCIMVDY 350
Cdd:TIGR03600 234 AEQLGERLLASKSGINTGNIRTGRFNDSEFNRLLNAVDRLSEKDLYIDDTGGLTVAQIRSIARRIKRKKGG-LDLIVVDY 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 351 LQLMKvPGMGDNRVGEISEISRSLKALAKEMQCPVIALSQLNRSLENRPNKRPVMSDLRESGAIEQDADLIMFIYRDEVY 430
Cdd:TIGR03600 313 IQLMA-PARGRDRNEELGGISRGLKALAKELDVPVVLLAQLNRGSEKRTDKRPIMSDLRDSGAIEQDADVIGLIHREGYY 391
|
410 420
....*....|....*....|....*....
gi 491320778 431 NKESKEAGTAEIIIGKQRNGPIGTVRLAF 459
Cdd:TIGR03600 392 DAREPPAGIAELILAKNRHGPTGTVELLF 420
|
|
| PRK05636 |
PRK05636 |
replicative DNA helicase; Provisional |
22-470 |
2.34e-127 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180177 [Multi-domain] Cd Length: 505 Bit Score: 379.57 E-value: 2.34e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 22 SGALKEFRTPPHNLAIEQAVLAALMTVAESLEQVGDVLQESDFYATRHKYIYRAIDTLAKENSPYDAVLVNDWLIKHNLL 101
Cdd:PRK05636 61 SREYRDFRQPPYDNEAEQGVLGAMLLSPDTVIDIVEVLTPEDFYRPAHQLIFQAIIDLFSDNKEIDPVIVAGRLDRTNDL 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 102 DAIGGEEYLMQLMADSPSSfYNLETYAAKIKEFSTLRNMIKVSSEILQNAYD-TKGRTVSEILDLAETNIFQIaeqhNNN 180
Cdd:PRK05636 141 ERVGGAPYLHTLIQSVPTA-ANARYYAEIVSEKAVLRRLVDAGTRVVQLGYEgDEGAEIDSVIDRAQQEVFAV----SQK 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 181 KKNAGPKAINTVVADVFDKLNELSQMDGNITGLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLVESVLFNNDL 260
Cdd:PRK05636 216 NQSEDYAVLADILDPTMDELEMLSSQGGIATGIPTGFKDLDDLTNGLRGGQMIIVAARPGVGKSTLALDFMRSASIKHNK 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 261 PALVYSMEMPADSIAMRLISSYGKVHQGNLRSGKLSGDEWSKVTGTILQLQEKHLYIDDSSALPPTEVRSRARRIAKQHG 340
Cdd:PRK05636 296 ASVIFSLEMSKSEIVMRLLSAEAEVRLSDMRGGKMDEDAWEKLVQRLGKIAQAPIFIDDSANLTMMEIRSKARRLKQKHD 375
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 341 gkLGCIMVDYLQLMKVPGMGDNRVGEISEISRSLKALAKEMQCPVIALSQLNRSLENRPNKRPVMSDLRESGAIEQDADL 420
Cdd:PRK05636 376 --LKLIVVDYLQLMSSGKRVESRQQEVSEFSRQLKLLAKELDVPLIAISQLNRGPESRTDKRPQLADLRESGSLEQDADM 453
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 491320778 421 IMFIYRDEVYNKESKEAGTAEIIIGKQRNGPIGTVRLAFEGQYTRFSNLS 470
Cdd:PRK05636 454 VMLLYRPDSQDKDDERAGEADIILAKHRGGPIDTVQVAHQLHYSRFVDMA 503
|
|
| PRK07773 |
PRK07773 |
replicative DNA helicase; Validated |
29-417 |
7.99e-123 |
|
replicative DNA helicase; Validated
Pssm-ID: 236093 [Multi-domain] Cd Length: 886 Bit Score: 379.48 E-value: 7.99e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 29 RTPPHNLAIEQAVLAALMTVAESLEQVGDVLQESDFYATRHKYIYRAIDTLAKENSPYDAVLVNDWLIKHNLLDAIGGEE 108
Cdd:PRK07773 22 RQPPQDLAAEQSVLGGMLLSKEAIARVLERLRPGAFYRPAHQNIYDAILDLYGRGEPADLVTVAAELDRRGLLERIGGAP 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 109 YLMQLMADSPSSfYNLETYAAKIKEFSTLRNMIKVSSEILQNAYDTkGRTVSEILDLAETNIFQIAEQHnnnkKNAGPKA 188
Cdd:PRK07773 102 YLHTLISTVPTA-ANADYYARIVAEKALLRRLIEAGTRIVQYGYAE-GADVAEVVDRAQAEIYDVTDRR----LSEDFVA 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 189 INTVVADVFDKLNELSQMDGNITGLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLVESVLFNNDLPALVYSME 268
Cdd:PRK07773 176 LEDLLQPTFDEIDAIASSGGLARGVPTGFTELDAMTNGLHPGQLIIVAARPSMGKTTFGLDFARNCAIRHRLAVAIFSLE 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 269 MPADSIAMRLISSYGKVHQGNLRSGKLSGDEWSKVTGTILQLQEKHLYIDDSSALPPTEVRSRARRIAKQHggKLGCIMV 348
Cdd:PRK07773 256 MSKEQLVMRLLSAEAKIKLSDMRSGRMSDDDWTRLARAMGEISEAPIFIDDTPNLTVMEIRAKARRLRQEA--NLGLIVV 333
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 491320778 349 DYLQLMKVPGMGDNRVGEISEISRSLKALAKEMQCPVIALSQLNRSLENRPNKRPVMSDLRESGAIEQD 417
Cdd:PRK07773 334 DYLQLMTSGKKYENRQQEVSEISRHLKLLAKELEVPVVALSQLSRGVEQRTDKRPMLSDLRESGCLTGD 402
|
|
| PRK06321 |
PRK06321 |
replicative DNA helicase; Provisional |
9-471 |
2.82e-114 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180528 [Multi-domain] Cd Length: 472 Bit Score: 344.90 E-value: 2.82e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 9 KPTPVKTESssndsgalkefrtPPHNLAIEQAVLAALMTVAESLEQVGDVLQESDFYATRHKYIYRAIDTLAKENSPYDA 88
Cdd:PRK06321 7 KPQPTQLLS-------------PPNSKESEMIVLGCMLTSVNYLNLAANQLQEDDFYFLEHKIIFRVLQDAFKSDKPIDV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 89 VLVNDWLIKHNLLDAIGGEEYLMQLMADSPSSFYnLETYAAKIKEFSTLRNMIKVSSEILQNAYDtKGRTVSEILDLAET 168
Cdd:PRK06321 74 HLAGEELKRRNQLNVIGGPSYLITLAEFAGTSAY-IEEYAEIIRSKSILRKMIQTAKEIEKKALE-EPKDVATALDEAQN 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 169 NIFQIAEQHNNNKknagpkaiNTVVADVF-------DK--LNELSQM------------DGNITGLTTGFVELDNKTSGM 227
Cdd:PRK06321 152 LLFKISQTTNLAQ--------YVLVADKLkgltsskDKpfLLQLQERqeafqqsaqgdsSPMISGIPTHFIDLDKMINGF 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 228 QAGDLIIVAARPSMGKTTFAMNLVESVLFNNDLPALVYSMEMPADSIAMRLISSYGKVHQGNLRSGKLSGDEWSKVTGTI 307
Cdd:PRK06321 224 SPSNLMILAARPAMGKTALALNIAENFCFQNRLPVGIFSLEMTVDQLIHRIICSRSEVESKKISVGDLSGRDFQRIVSVV 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 308 LQLQEKHLYIDDSSALPPTEVRSRARRIAKQHGgkLGCIMVDYLQLMKVPGM---GDNRVGEISEISRSLKALAKEMQCP 384
Cdd:PRK06321 304 NEMQEHTLLIDDQPGLKITDLRARARRMKESYD--IQFLIIDYLQLLSGSGNlrnSESRQTEISEISRMLKNLARELNIP 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 385 VIALSQLNRSLENRPNKRPVMSDLRESGAIEQDADLIMFIYRDEVYNKESKeAGTAEIIIGKQRNGPIGTVRLAFEGQYT 464
Cdd:PRK06321 382 ILCLSQLSRKVEDRANHRPMMSDLRESGSIEQDSDLVMFLLRREYYDPNDK-PGTAELIVAKNRHGSIGSVPLVFEKEFA 460
|
....*..
gi 491320778 465 RFSNLSP 471
Cdd:PRK06321 461 RFRNYAA 467
|
|
| PRK06749 |
PRK06749 |
replicative DNA helicase; Provisional |
34-469 |
3.82e-83 |
|
replicative DNA helicase; Provisional
Pssm-ID: 168658 [Multi-domain] Cd Length: 428 Bit Score: 263.35 E-value: 3.82e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 34 NLAIEQAVLAALMTVAESLEQVGdvLQESDFYATRHKYIYRAIDTLAKENSPYDAVLVNDwLIKHNLLDAIGGEEYLMQL 113
Cdd:PRK06749 5 NVEAEKTVLGSLLLDGELIKECR--LTEQYFSMPVHKSIFQLMRKMEDEGQPIDLVTFTS-RVDPNFLKGIGGMEYFIGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 114 MADSPSSfYNLETYAAKIKEFSTLRNMIKVSSEI---LQNAYDTK--GRTVSEILDLAETNIFQiaeqhNNNKKNAgpka 188
Cdd:PRK06749 82 MDGVPTT-SNFSYYEGLVRGAWKMYQAGVLGHKMgerLIAEKSEKiiGETITALCELEEKDCVC-----EFDLKDA---- 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 189 intvvadVFDKLNELSQMDGNITGLTTGFVELDNKTSGMQAGDLIIVAARPSMGKTTFAMNLVESVLFNNDLPALvYSME 268
Cdd:PRK06749 152 -------LVDLYEELHQDAKEITGIETGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGAAVGL-FSLE 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 269 MPADSIAMRLISSYGKVHQGNLRSGK--LSGDEWSKVTGTILQLQEKHLYIDDSSALPPTEVRSRARRIAKQHGGKLGCI 346
Cdd:PRK06749 224 MSSKQLLKRMASCVGEVSGGRLKNPKhrFAMEDWEKVSKAFAEIGELPLEIYDNAGVTVQDIWMQTRKLKRKHGDKKILI 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 347 MVDYLQLMKV-PGMGDNRVGEISEISRSLKALAKEMQCPVIALSQLNRSLENRPNKRPVMSDLRESGAIEQDADLIMFIY 425
Cdd:PRK06749 304 IVDYLQLITGdPKHKGNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADVIMLMY 383
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 491320778 426 RDEVYNKESKEAGTAEIIIGKQRNGPIGTVRLAFEGQYTRFSNL 469
Cdd:PRK06749 384 REDYYDKETMQKEMTEIHVAKHRNGPVGSFKLRFLKEFGRFVEG 427
|
|
| DnaB |
pfam00772 |
DnaB-like helicase N terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
30-133 |
4.35e-28 |
|
DnaB-like helicase N terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This N-terminal domain is required both for interaction with other proteins in the primosome and for DnaB helicase activity.
Pssm-ID: 395624 [Multi-domain] Cd Length: 103 Bit Score: 107.32 E-value: 4.35e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 30 TPPHNLAIEQAVLAALMTVAESLEQVGDVLQESDFYATRHKYIYRAIDTLAKENSPYDAVLVNDWLIKHNLLDAIGGEEY 109
Cdd:pfam00772 1 VPPHNIEAEQAVLGALLLDPEAIDEVADILKPEDFYDPAHRLIFEAILDLYDKGEPIDPVTVAEELEKKGKLEDVGGIAY 80
|
90 100
....*....|....*....|....
gi 491320778 110 LMQLMADSPSSfYNLETYAAKIKE 133
Cdd:pfam00772 81 LAELAANVPSA-ANIEYYARIVKE 103
|
|
| PRK07773 |
PRK07773 |
replicative DNA helicase; Validated |
413-470 |
2.25e-22 |
|
replicative DNA helicase; Validated
Pssm-ID: 236093 [Multi-domain] Cd Length: 886 Bit Score: 100.59 E-value: 2.25e-22
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 491320778 413 AIEQDADLIMFIYRDEVYNKESKEAGTAEIIIGKQRNGPIGTVRLAFEGQYTRFSNLS 470
Cdd:PRK07773 827 SIEQDADVVILLYRPDYYDRDDPRGGEAEFIVAKHRNGPTGTVTLAFQLHLSRFANLA 884
|
|
| RecA-like_Gp4D_helicase |
cd19483 |
RecA-like domain of Escherichia coli bacteriophage T7 Gp4D helicase; This family includes the ... |
233-454 |
1.26e-13 |
|
RecA-like domain of Escherichia coli bacteriophage T7 Gp4D helicase; This family includes the RecA-like domain of the Gp4D fragment of the Gene4 helicase-primase (Gp4) from bacteriophage T7. Gp4D (residues 241-566) is the minimal fragment of the Gp4 that forms hexameric rings, it contains the helicase domain and the linker connecting the helicase and primase domains. Helicases are ring-shaped oligomeric enzymes that unwind DNA at the replication fork; they couple NTP hydrolysis to the unwinding of nucleic acid duplexes into their component strands. This family belongs to the RecA-like NTPase superfamily which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410891 [Multi-domain] Cd Length: 231 Bit Score: 70.29 E-value: 1.26e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 233 IIVAARPSMGKTTFAMNLVESVLFNNDLPALVYSMEMPADSIAMRLISS-YGKVHQGNLRSGKLSGDEwSKVTGTILQLQ 311
Cdd:cd19483 1 VTIGAGSGIGKSTIVRELAYHLITEHGEKVGIISLEESVEETAKGLAGKhLGKPEPLELPRDDITEEE-EDDAFDNELGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 312 EKHLYIDDSSALPPTEVRSRARRIAKQHGGKLgcIMVDYLQLMkVPGM-GDNRVGEISEISRSLKALAKEMQCPVIALSQ 390
Cdd:cd19483 80 GRFFLYDHFGSLDWDNLKEKIRYMVKVLGCKV--IVLDHLTIL-VSGLdSSDERKELDEIMTELAALVKELGVTIILVSH 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 491320778 391 LNRSLENRP---NKRPVMSDLRESGAIEQDADLIMFIYRDEvYNKESKEAGTAEIIIGKQRN----GPIGT 454
Cdd:cd19483 157 LRRPGGGKGheeGGEVSESDLRGSSAIAQLSDYVIGLERNK-QADDPVERNTTRVRVLKNRFtgetGIAGT 226
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
213-460 |
2.35e-06 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 48.37 E-value: 2.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 213 LTTGFVELDNKTS-GMQAGDLIIVAARPSMGKTTFAMNLVESVLFNNDlPALVYSMEMPADSIaMRLISSYGKVHQGNLR 291
Cdd:COG0467 2 VPTGIPGLDELLGgGLPRGSSTLLSGPPGTGKTTLALQFLAEGLRRGE-KGLYVSFEESPEQL-LRRAESLGLDLEEYIE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 292 SGKLsgdewskvtgTILQLQEKHLYIDdssalpPTEVRSRARRIAKQHGGKLgcIMVD----YLQLMKVPGMgdnrvgeI 367
Cdd:COG0467 80 SGLL----------RIIDLSPEELGLD------LEELLARLREAVEEFGAKR--VVIDslsgLLLALPDPER-------L 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 368 SEISRSLKALAKEMQCPVIALSQLnrslenrpnkrPVMSDLRESGAIEQDADLIMFIYRDEVYNKESKeagtaEIIIGKQ 447
Cdd:COG0467 135 REFLHRLLRYLKKRGVTTLLTSET-----------GGLEDEATEGGLSYLADGVILLRYVELGGELRR-----ALSVLKM 198
|
250
....*....|...
gi 491320778 448 RNGPIGTVRLAFE 460
Cdd:COG0467 199 RGSAHDRTIREFE 211
|
|
| 41 |
PHA02542 |
41 helicase; Provisional |
226-428 |
5.42e-06 |
|
41 helicase; Provisional
Pssm-ID: 222864 [Multi-domain] Cd Length: 473 Bit Score: 48.90 E-value: 5.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 226 GMQAGDLIIVAARPSMGKTTFAMNLVESVLFNNdLPALVYSMEMPADSIAMRLISSYGKVHQGNLRsgKLSGDEWSKVTG 305
Cdd:PHA02542 186 GAERKTLNVLLAGVNVGKSLGLCSLAADYLQQG-YNVLYISMEMAEEVIAKRIDANLLDVSLDDID--DLSKAEYKAKME 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 306 TILQLQEKHLYIDD--SSALPPTEVRSRARRIAKQHGGKLGCIMVDYLQLM---KVPGMGDNRVGEISEISRSLKALAKE 380
Cdd:PHA02542 263 KLRSKTQGKLIIKQypTGGAHAGHFRALLNELKLKKNFKPDVIIVDYLGICassRLRVSSENSYTYVKAIAEELRGLAVE 342
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 491320778 381 MQCPVIALSQLNRSleNRPNKRPVMSDLRESGAIEQDADLIMFIYRDE 428
Cdd:PHA02542 343 HDVVVWTAAQTTRS--GWDSSDVDMSDTAESAGLPATADFMLAVIETE 388
|
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
229-392 |
8.10e-05 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 43.52 E-value: 8.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 229 AGDLIIVAARPSMGKTTFAMNLVESVL----FNND------LPALVYSMEMPADSIAMRLIssygKVHQGNLRSGKLSGD 298
Cdd:pfam13481 32 AGGLGLLAGAPGTGKTTLALDLAAAVAtgkpWLGGprvpeqGKVLYVSAEGPADELRRRLR----AAGADLDLPARLLFL 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320778 299 EWskvtGTILQLqekhLYIDDSSALPPTEVRSRARRIAKQHGGKLgcIMVDYLQLMKvpGMGDNRVGEISEISRSLKALA 378
Cdd:pfam13481 108 SL----VESLPL----FFLDRGGPLLDADVDALEAALEEVEDPDL--VVIDPLARAL--GGDENSNSDVGRLVKALDRLA 175
|
170
....*....|....
gi 491320778 379 KEMQCPVIALSQLN 392
Cdd:pfam13481 176 RRTGATVLLVHHVG 189
|
|
| |
