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Conserved domains on  [gi|491320759|ref|WP_005178725|]
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MULTISPECIES: cytochrome o ubiquinol oxidase subunit I [Acinetobacter]

Protein Classification

cytochrome ubiquinol oxidase subunit I( domain architecture ID 10798640)

cytochrome ubiquinol oxidase subunit I is a heme-copper oxygen reductase, located in the mitochondrial inner membrane or the bacterial inner cell membrane, which catalyzes the reduction of molecular oxygen to water and is typically the terminal electron ac

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CyoB TIGR02843
cytochrome o ubiquinol oxidase, subunit I; Cytochrome o terminal oxidase complex is the ...
 2-646 0e+00

cytochrome o ubiquinol oxidase, subunit I; Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain which reacts with oxygen, reducing it to water with the concomitant transport of 4 protons across the membrane. Also known as the cytochrome bo complex, cytochrome o ubiquinol oxidase contains four subunits, two heme b cofactors and a copper atom which is believed to be the oxygen active site. This complex is structurally related to the cytochrome caa3 oxidases which utilize cytochrome c as the reductant and contain heme a cofactors, as well as the intermediate form aa3 oxidases which also react directly with quinones as the reductant. [Energy metabolism, Electron transport]


:

Pssm-ID: 131890  Cd Length: 646  Bit Score: 1126.30  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759    2 FGKLGLDAIPY-DPIVQATVVMMILGGLVLVAGITYFKKWGYLWNEWFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMRL 80
Cdd:TIGR02843   1 FGKLTLDAIPYhEPIIMVTLAAVALGGLALLGAITYFRKWGYLWNEWLTTVDHKKIGIMYIIVALVMLLRGFADAIMMRT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759   81 QQFLARGGGEGYLHPEHYDQIFTAHGVIMIFFVAMGLVVGLMNISVPLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLA 160
Cdd:TIGR02843  81 QQALASGGSAGYLPPHHYDQIFTAHGVIMIFFVAMPFVFGLMNLVVPLQIGARDVAFPFLNSLSFWLTVVGAILVNVSLG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  161 LGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGTLLTGVNFFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLIIA 240
Cdd:TIGR02843 161 VGEFAQTGWLAYPPLSELQYSPGVGVDYYIWALQISGIGTLLTGINFFVTIIKMRAPGMTLMKMPVFTWTSLCSNVLIIA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  241 AFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWTWGHPEVYILVLPAFGIYSEVVATFSRKTLFGYKSMVYATV 320
Cdd:TIGR02843 241 SFPILTVTLALLTLDRYLGMHFFTNEAGGNPMMYVNLIWAWGHPEVYILILPAFGIFSEVVATFSRKRLFGYTSMVWATI 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  321 AITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGVKIFSWLFTMYKGRITYTTPMLWTLGFLVTFGIGGLTGVLM 400
Cdd:TIGR02843 321 AITVLSFIVWLHHFFTMGAGANVNAFFGIATMIIAIPTGVKIFNWLFTMYKGRIRFETPMLWTIGFMVTFSIGGMTGVLL 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  401 AVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWPKMFGWRLNETWGKAAFWFWFLGFYFAFMPLYILGFMGMTR 480
Cdd:TIGR02843 401 AVPPADFVLHNSLFLIAHFHNVIIGGVVFGCFAGLTYWFPKAFGFKLNEKLGKRSFWCWFIGFYLAFMPLYILGFMGMTR 480

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  481 RLNTYDNPDWDPYVMIAMVGAVMIAIGIACFLMQIIVGFLQRNQRLDHTGDPWDGRTLEWATSSPAPFYNFAHLPKINGI 560
Cdd:TIGR02843 481 RLNHYDNPEWHPMLIIAAFGAFLIACGILCQIIQIFVSIRDRDQNRDTTGDPWGGRTLEWSTSSPPPFYNFAVIPKVQDR 560

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  561 DTFWTDKENGVAYAKPAKYEDIHMPTNRAAGFVIAMFITVMGFALIWHIWWLVVVTFIASIISFIVSSFTKKVDYYVPAA 640
Cdd:TIGR02843 561 DAFWDMKKKGVAYPRPAKYEDIHMPKNTAAGFIIGAFSLVFGFALVWHIWWLAIIGFVGIIATLIVRSFDDDVDYYVPAE 640


                  ....*.
gi 491320759  641 EVERIE 646
Cdd:TIGR02843 641 EVKKIE 646
 
Name Accession Description Interval E-value
CyoB TIGR02843
cytochrome o ubiquinol oxidase, subunit I; Cytochrome o terminal oxidase complex is the ...
 2-646 0e+00

cytochrome o ubiquinol oxidase, subunit I; Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain which reacts with oxygen, reducing it to water with the concomitant transport of 4 protons across the membrane. Also known as the cytochrome bo complex, cytochrome o ubiquinol oxidase contains four subunits, two heme b cofactors and a copper atom which is believed to be the oxygen active site. This complex is structurally related to the cytochrome caa3 oxidases which utilize cytochrome c as the reductant and contain heme a cofactors, as well as the intermediate form aa3 oxidases which also react directly with quinones as the reductant. [Energy metabolism, Electron transport]


Pssm-ID: 131890  Cd Length: 646  Bit Score: 1126.30  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759    2 FGKLGLDAIPY-DPIVQATVVMMILGGLVLVAGITYFKKWGYLWNEWFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMRL 80
Cdd:TIGR02843   1 FGKLTLDAIPYhEPIIMVTLAAVALGGLALLGAITYFRKWGYLWNEWLTTVDHKKIGIMYIIVALVMLLRGFADAIMMRT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759   81 QQFLARGGGEGYLHPEHYDQIFTAHGVIMIFFVAMGLVVGLMNISVPLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLA 160
Cdd:TIGR02843  81 QQALASGGSAGYLPPHHYDQIFTAHGVIMIFFVAMPFVFGLMNLVVPLQIGARDVAFPFLNSLSFWLTVVGAILVNVSLG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  161 LGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGTLLTGVNFFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLIIA 240
Cdd:TIGR02843 161 VGEFAQTGWLAYPPLSELQYSPGVGVDYYIWALQISGIGTLLTGINFFVTIIKMRAPGMTLMKMPVFTWTSLCSNVLIIA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  241 AFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWTWGHPEVYILVLPAFGIYSEVVATFSRKTLFGYKSMVYATV 320
Cdd:TIGR02843 241 SFPILTVTLALLTLDRYLGMHFFTNEAGGNPMMYVNLIWAWGHPEVYILILPAFGIFSEVVATFSRKRLFGYTSMVWATI 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  321 AITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGVKIFSWLFTMYKGRITYTTPMLWTLGFLVTFGIGGLTGVLM 400
Cdd:TIGR02843 321 AITVLSFIVWLHHFFTMGAGANVNAFFGIATMIIAIPTGVKIFNWLFTMYKGRIRFETPMLWTIGFMVTFSIGGMTGVLL 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  401 AVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWPKMFGWRLNETWGKAAFWFWFLGFYFAFMPLYILGFMGMTR 480
Cdd:TIGR02843 401 AVPPADFVLHNSLFLIAHFHNVIIGGVVFGCFAGLTYWFPKAFGFKLNEKLGKRSFWCWFIGFYLAFMPLYILGFMGMTR 480

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  481 RLNTYDNPDWDPYVMIAMVGAVMIAIGIACFLMQIIVGFLQRNQRLDHTGDPWDGRTLEWATSSPAPFYNFAHLPKINGI 560
Cdd:TIGR02843 481 RLNHYDNPEWHPMLIIAAFGAFLIACGILCQIIQIFVSIRDRDQNRDTTGDPWGGRTLEWSTSSPPPFYNFAVIPKVQDR 560

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  561 DTFWTDKENGVAYAKPAKYEDIHMPTNRAAGFVIAMFITVMGFALIWHIWWLVVVTFIASIISFIVSSFTKKVDYYVPAA 640
Cdd:TIGR02843 561 DAFWDMKKKGVAYPRPAKYEDIHMPKNTAAGFIIGAFSLVFGFALVWHIWWLAIIGFVGIIATLIVRSFDDDVDYYVPAE 640


                  ....*.
gi 491320759  641 EVERIE 646
Cdd:TIGR02843 641 EVKKIE 646
PRK15017 PRK15017
cytochrome o ubiquinol oxidase subunit I; Provisional
 1-655 0e+00

cytochrome o ubiquinol oxidase subunit I; Provisional


Pssm-ID: 184978  Cd Length: 663  Bit Score: 949.76  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759   1 MFGKLGLDAIPY-DPIVQATVVMMILGGLVLVAGITYFKKWGYLWNEWFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMR 79
Cdd:PRK15017   1 MFGKLSLDAVPFhEPIVMVTIAAIILGGLALVGLITYFGKWTYLWKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  80 LQQFLARGGGEGYLHPEHYDQIFTAHGVIMIFFVAMGLVVGLMNISVPLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSL 159
Cdd:PRK15017  81 SQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 160 ALGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGTLLTGVNFFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLII 239
Cdd:PRK15017 161 GVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMTMFKMPVFTWASLCANVLII 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 240 AAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWTWGHPEVYILVLPAFGIYSEVVATFSRKTLFGYKSMVYAT 319
Cdd:PRK15017 241 ASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWAT 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 320 VAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGVKIFSWLFTMYKGRITYTTPMLWTLGFLVTFGIGGLTGVL 399
Cdd:PRK15017 321 VCITVLSFIVWLHHFFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVL 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 400 MAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWPKMFGWRLNETWGKAAFWFWFLGFYFAFMPLYILGFMGMT 479
Cdd:PRK15017 401 LAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFWIIGFFVAFMPLYALGFMGMT 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 480 RRLNTYDNPDWDPYVMIAMVGAVMIAIGIACFLMQIIVGFLQRNQRLDHTGDPWDGRTLEWATSSPAPFYNFAHLPKING 559
Cdd:PRK15017 481 RRLSQQIDPQFHTMLMIAASGAALIALGILCQVIQMYVSIRDRDQNRDLTGDPWGGRTLEWATSSPPPFYNFAVVPHVHE 560

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 560 IDTFWTDKENGVAYAKPAKYEDIHMPTNRAAGFVIAMFITVMGFALIWHIWWLVVVTFIASIISFIVSSFTKKVDYYVPA 639
Cdd:PRK15017 561 RDAFWEMKEKGEAYKQPDHYEEIHMPKNSGAGIVIAAFSTIFGFAMIWHIWWLAIVGFAGMIITWIVKSFDEDVDYYVPV 640

                        650
                 ....*....|....*.
gi 491320759 640 AEVERIENERYALLEK 655
Cdd:PRK15017 641 AEIEKLENQHFDEITK 656
Ubiquinol_Oxidase_I cd01662
Ubiquinol oxidase subunit I. Ubiquinol oxidase, the terminal oxidase in the respiratory ...
 47-551 0e+00

Ubiquinol oxidase subunit I. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane. It catalyzes the reduction of O2 and simultaneously pumps protons across the membrane. The number of subunits in ubiquinol oxidase varies from two to five. Subunit I contains a heme-copper binuclear center (the active site where O2 is reduced to water) formed by a high-spin heme and a copper ion. It also contains a low-spin heme, believed to participate in the transfer of electrons from ubiquinol to the binuclear center. For every reduction of an O2 molecule, eight protons are taken from the inside aqueous compartment and four electrons are taken from ubiquinol on the opposite side of the membrane. The four electrons and four of the protons are used in the reduction of O2; the four remaining protons are pumped across the membrane. This charge separation of four charges contributes to the electrochemical gradient used for ATP synthesis. Two proton channels, the D-pathway and K-pathway, leading to the binuclear center have been identified in subunit I. It is generally believed that the channels contain water molecules that act as 'proton wires' to transfer the protons. A well-defined pathway for the transfer of pumped protons beyond the binuclear center has not been identified. Electrons are believed to be transferred directly from ubiquinol (the electron donor) to the low-spin heme, and directly from the low-spin heme to the binuclear center.


Pssm-ID: 238832  Cd Length: 501  Bit Score: 819.13  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  47 WFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMRLQQFLARGGgegYLHPEHYDQIFTAHGVIMIFFVAMGLVVGLMNISV 126
Cdd:cd01662    1 WLTTVDHKRIGIMYIITAFVFFLRGGVDALLMRTQLALPGND---FLSPEHYNQIFTMHGTIMIFLFAMPLVFGLMNYLV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 127 PLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLALGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGTLLTGVN 206
Cdd:cd01662   78 PLQIGARDVAFPRLNALSFWLFLFGGLLLNASLLIGGFPDAGWFAYPPLSGLEYSPGVGVDYWILGLQFSGIGTLLGAIN 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 207 FFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWTWGHPEV 286
Cdd:cd01662  158 FIVTILKMRAPGMTLMRMPIFTWTTLVTSILILFAFPVLTAALALLELDRYFGTHFFTNALGGNPMLWQHLFWIFGHPEV 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 287 YILVLPAFGIYSEVVATFSRKTLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGVKIFSWL 366
Cdd:cd01662  238 YILILPAFGIFSEIVPTFSRKPLFGYRSMVYATVAIGFLSFGVWVHHMFTTGAGALVNAFFSIATMIIAVPTGVKIFNWL 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 367 FTMYKGRITYTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWPKMFGWR 446
Cdd:cd01662  318 FTMWRGRIRFETPMLWAIGFLVTFVIGGLTGVMLASPPADFQVHDTYFVVAHFHYVLIGGVVFPLFAGFYYWFPKMFGRM 397

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 447 LNETWGKAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYD-NPDWDPYVMIAMVGAVMIAIGIACFLMQIIVGFlqRNQR 525
Cdd:cd01662  398 LNERLGKWSFWLWFIGFNLTFFPMHILGLMGMPRRVYTYLpGPGWDPLNLISTIGAFLIAAGVLLFLINVIVSI--RKGK 475

                        490       500
                 ....*....|....*....|....*.
gi 491320759 526 LDHTGDPWDGRTLEWATSSPAPFYNF 551
Cdd:cd01662  476 RDATGDPWGARTLEWATSSPPPAYNF 501
CyoB COG0843
Heme/copper-type cytochrome/quinol oxidase, subunit 1 [Energy production and conversion];
39-578 0e+00

Heme/copper-type cytochrome/quinol oxidase, subunit 1 [Energy production and conversion];


Pssm-ID: 440605  Cd Length: 535  Bit Score: 756.20  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  39 KWGYLWNEWFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMRLQQFLArggGEGYLHPEHYDQIFTAHGVIMIFFVAMGLV 118
Cdd:COG0843    1 EWGSGWRRWLTTVDHKRIGIMYLVTAFVFLLIGGLLALLMRLQLAGP---GLGLLSPETYNQLFTMHGTIMIFFFATPFL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 119 VGLMNISVPLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLALGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGL 198
Cdd:COG0843   78 AGFGNYLVPLQIGARDMAFPRLNALSFWLYLFGGLLLLISLFVGGAADVGWTFYPPLSGLEASPGVGVDLWLLGLALFGV 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 199 GTLLTGVNFFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLI 278
Cdd:COG0843  158 GSILGGVNFIVTILKMRAPGMTLMRMPLFTWAALVTSILILLAFPVLAAALLLLLLDRSLGTHFFDPAGGGDPLLWQHLF 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 279 WTWGHPEVYILVLPAFGIYSEVVATFSRKTLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPT 358
Cdd:COG0843  238 WFFGHPEVYILILPAFGIVSEIIPTFSRKPLFGYKAMVLATVAIAFLSFLVWAHHMFTPGISPLVKAFFSIATMLIAVPT 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 359 GVKIFSWLFTMYKGRITYTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFY 438
Cdd:COG0843  318 GVKVFNWIATMWRGRIRFTTPMLFALGFIILFVIGGLTGVMLASVPLDYQVHDTYFVVAHFHYVLIGGVVFAFFAGLYYW 397

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 439 WPKMFGWRLNETWGKAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYD-NPDWDPYVMIAMVGAVMIAIGIACFLMQIIV 517
Cdd:COG0843  398 FPKMTGRMLNERLGKIHFWLWFIGFNLTFFPMHILGLLGMPRRYATYPpEPGWQPLNLISTIGAFILAVGFLLFLINLVV 477

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 491320759 518 GFLQRNqrlDHTGDPWDGRTLEWATSSPAPFYNFAHLPKINGIDTFWTDKENGVAYAKPAK 578
Cdd:COG0843  478 SLRKGP---KAGGNPWGARTLEWATPSPPPLYNFASIPVVRSRDPAYDYKKPGADFVPPAE 535
COX1 pfam00115
Cytochrome C and Quinol oxidase polypeptide I; Cytochrome c oxidase (E.C:7.1.1.9) is a key ...
 55-503 3.05e-143

Cytochrome C and Quinol oxidase polypeptide I; Cytochrome c oxidase (E.C:7.1.1.9) is a key enzyme in aerobic metabolism. Proton pumping haem-copper oxidases represent the terminal, energy-transfer enzymes of respiratory chains in prokaryotes and eukaryotes. The CuB-haem a3 (or haem o) binuclear centre, associated with the largest subunit I of cytochrome c and ubiquinol oxidases (E.C:1.10.3.11), is directly involved in the coupling between dioxygen reduction and proton pumping. Some terminal oxidases generate a transmembrane proton gradient across the plasma membrane (prokaryotes) or the mitochondrial inner membrane (eukaryotes). The enzyme complex consists of 3-4 subunits (prokaryotes) up to 13 polypeptides (mammals) of which only the catalytic subunit (equivalent to mammalian subunit I (COXI) is found in all haem-copper respiratory oxidases. The presence of a bimetallic centre (formed by a high-spin haem and copper B) as well as a low-spin haem, both ligated to six conserved histidine residues near the outer side of four transmembrane spans within CO I is common to all family members.


Pssm-ID: 459678  Cd Length: 432  Bit Score: 423.91  E-value: 3.05e-143
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759   55 KIGIMYIIVSVVMLLRGFADAIMMRLQQFLArggGEGYLHPEHYDQIFTAHGVIMIFFVAMGLVVGLMNISVPLQIGARD 134
Cdd:pfam00115   1 RIGLLYLVTALVWFLVGGLLGLLIRLQLAFP---GLNFLSPLTYNQLRTLHGNLMIFWFATPFLFGFGNYLVPLMIGARD 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  135 VAFPLLNSLSFWLFAGAAGLMMVSLAlgeFAATGWMAYPPLsgieyspgVGMDYYIWALQISGLGTLLTGVNFFVTIIKM 214
Cdd:pfam00115  78 MAFPRLNALSFWLVVLGAVLLLASFG---GATTGWTEYPPL--------VGVDLWYIGLLLAGVSSLLGAINFIVTILKR 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  215 RAPGMKlMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGfhfftnDMGGSPMLYVNLIWTWGHPEVYILVLPAF 294
Cdd:pfam00115 147 RAPGMT-LRMPLFVWAILATAILILLAFPVLAAALLLLLLDRSLG------AGGGDPLLDQHLFWWFGHPEVYILILPAF 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  295 GIYSEVVATFSRKTLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGVKIFSWLFTMYKGRI 374
Cdd:pfam00115 220 GIIYYILPKFAGRPLFGYKLSVLAFWLIAFLGFLVWAHHLFTTGLPPWLQALFSVFSMLIAVPSGVKVFNWLATLWGGWI 299

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  375 T-YTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWPKMFGWRLNETWGK 453
Cdd:pfam00115 300 RfRTTPMLFFLGFAFLFIIGGLTGVMLALPPVNYYVHDTYFVVAHFHYVLFGGVVFALFGGIYYWLPKLTGRMYSEKLGK 379

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 491320759  454 AAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYDN---PDWDPYVMIAMVGAVM 503
Cdd:pfam00115 380 LHFWLLFIGFNLTFFPMHILGLLGMPRRYAPPFIetvPAFQPLNWIRTIGGVL 432
 
Name Accession Description Interval E-value
CyoB TIGR02843
cytochrome o ubiquinol oxidase, subunit I; Cytochrome o terminal oxidase complex is the ...
 2-646 0e+00

cytochrome o ubiquinol oxidase, subunit I; Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain which reacts with oxygen, reducing it to water with the concomitant transport of 4 protons across the membrane. Also known as the cytochrome bo complex, cytochrome o ubiquinol oxidase contains four subunits, two heme b cofactors and a copper atom which is believed to be the oxygen active site. This complex is structurally related to the cytochrome caa3 oxidases which utilize cytochrome c as the reductant and contain heme a cofactors, as well as the intermediate form aa3 oxidases which also react directly with quinones as the reductant. [Energy metabolism, Electron transport]


Pssm-ID: 131890  Cd Length: 646  Bit Score: 1126.30  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759    2 FGKLGLDAIPY-DPIVQATVVMMILGGLVLVAGITYFKKWGYLWNEWFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMRL 80
Cdd:TIGR02843   1 FGKLTLDAIPYhEPIIMVTLAAVALGGLALLGAITYFRKWGYLWNEWLTTVDHKKIGIMYIIVALVMLLRGFADAIMMRT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759   81 QQFLARGGGEGYLHPEHYDQIFTAHGVIMIFFVAMGLVVGLMNISVPLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLA 160
Cdd:TIGR02843  81 QQALASGGSAGYLPPHHYDQIFTAHGVIMIFFVAMPFVFGLMNLVVPLQIGARDVAFPFLNSLSFWLTVVGAILVNVSLG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  161 LGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGTLLTGVNFFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLIIA 240
Cdd:TIGR02843 161 VGEFAQTGWLAYPPLSELQYSPGVGVDYYIWALQISGIGTLLTGINFFVTIIKMRAPGMTLMKMPVFTWTSLCSNVLIIA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  241 AFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWTWGHPEVYILVLPAFGIYSEVVATFSRKTLFGYKSMVYATV 320
Cdd:TIGR02843 241 SFPILTVTLALLTLDRYLGMHFFTNEAGGNPMMYVNLIWAWGHPEVYILILPAFGIFSEVVATFSRKRLFGYTSMVWATI 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  321 AITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGVKIFSWLFTMYKGRITYTTPMLWTLGFLVTFGIGGLTGVLM 400
Cdd:TIGR02843 321 AITVLSFIVWLHHFFTMGAGANVNAFFGIATMIIAIPTGVKIFNWLFTMYKGRIRFETPMLWTIGFMVTFSIGGMTGVLL 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  401 AVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWPKMFGWRLNETWGKAAFWFWFLGFYFAFMPLYILGFMGMTR 480
Cdd:TIGR02843 401 AVPPADFVLHNSLFLIAHFHNVIIGGVVFGCFAGLTYWFPKAFGFKLNEKLGKRSFWCWFIGFYLAFMPLYILGFMGMTR 480

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  481 RLNTYDNPDWDPYVMIAMVGAVMIAIGIACFLMQIIVGFLQRNQRLDHTGDPWDGRTLEWATSSPAPFYNFAHLPKINGI 560
Cdd:TIGR02843 481 RLNHYDNPEWHPMLIIAAFGAFLIACGILCQIIQIFVSIRDRDQNRDTTGDPWGGRTLEWSTSSPPPFYNFAVIPKVQDR 560

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  561 DTFWTDKENGVAYAKPAKYEDIHMPTNRAAGFVIAMFITVMGFALIWHIWWLVVVTFIASIISFIVSSFTKKVDYYVPAA 640
Cdd:TIGR02843 561 DAFWDMKKKGVAYPRPAKYEDIHMPKNTAAGFIIGAFSLVFGFALVWHIWWLAIIGFVGIIATLIVRSFDDDVDYYVPAE 640


                  ....*.
gi 491320759  641 EVERIE 646
Cdd:TIGR02843 641 EVKKIE 646
PRK15017 PRK15017
cytochrome o ubiquinol oxidase subunit I; Provisional
 1-655 0e+00

cytochrome o ubiquinol oxidase subunit I; Provisional


Pssm-ID: 184978  Cd Length: 663  Bit Score: 949.76  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759   1 MFGKLGLDAIPY-DPIVQATVVMMILGGLVLVAGITYFKKWGYLWNEWFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMR 79
Cdd:PRK15017   1 MFGKLSLDAVPFhEPIVMVTIAAIILGGLALVGLITYFGKWTYLWKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  80 LQQFLARGGGEGYLHPEHYDQIFTAHGVIMIFFVAMGLVVGLMNISVPLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSL 159
Cdd:PRK15017  81 SQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 160 ALGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGTLLTGVNFFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLII 239
Cdd:PRK15017 161 GVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMTMFKMPVFTWASLCANVLII 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 240 AAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWTWGHPEVYILVLPAFGIYSEVVATFSRKTLFGYKSMVYAT 319
Cdd:PRK15017 241 ASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWAT 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 320 VAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGVKIFSWLFTMYKGRITYTTPMLWTLGFLVTFGIGGLTGVL 399
Cdd:PRK15017 321 VCITVLSFIVWLHHFFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVL 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 400 MAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWPKMFGWRLNETWGKAAFWFWFLGFYFAFMPLYILGFMGMT 479
Cdd:PRK15017 401 LAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFWIIGFFVAFMPLYALGFMGMT 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 480 RRLNTYDNPDWDPYVMIAMVGAVMIAIGIACFLMQIIVGFLQRNQRLDHTGDPWDGRTLEWATSSPAPFYNFAHLPKING 559
Cdd:PRK15017 481 RRLSQQIDPQFHTMLMIAASGAALIALGILCQVIQMYVSIRDRDQNRDLTGDPWGGRTLEWATSSPPPFYNFAVVPHVHE 560

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 560 IDTFWTDKENGVAYAKPAKYEDIHMPTNRAAGFVIAMFITVMGFALIWHIWWLVVVTFIASIISFIVSSFTKKVDYYVPA 639
Cdd:PRK15017 561 RDAFWEMKEKGEAYKQPDHYEEIHMPKNSGAGIVIAAFSTIFGFAMIWHIWWLAIVGFAGMIITWIVKSFDEDVDYYVPV 640

                        650
                 ....*....|....*.
gi 491320759 640 AEVERIENERYALLEK 655
Cdd:PRK15017 641 AEIEKLENQHFDEITK 656
Ubiquinol_Oxidase_I cd01662
Ubiquinol oxidase subunit I. Ubiquinol oxidase, the terminal oxidase in the respiratory ...
 47-551 0e+00

Ubiquinol oxidase subunit I. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane. It catalyzes the reduction of O2 and simultaneously pumps protons across the membrane. The number of subunits in ubiquinol oxidase varies from two to five. Subunit I contains a heme-copper binuclear center (the active site where O2 is reduced to water) formed by a high-spin heme and a copper ion. It also contains a low-spin heme, believed to participate in the transfer of electrons from ubiquinol to the binuclear center. For every reduction of an O2 molecule, eight protons are taken from the inside aqueous compartment and four electrons are taken from ubiquinol on the opposite side of the membrane. The four electrons and four of the protons are used in the reduction of O2; the four remaining protons are pumped across the membrane. This charge separation of four charges contributes to the electrochemical gradient used for ATP synthesis. Two proton channels, the D-pathway and K-pathway, leading to the binuclear center have been identified in subunit I. It is generally believed that the channels contain water molecules that act as 'proton wires' to transfer the protons. A well-defined pathway for the transfer of pumped protons beyond the binuclear center has not been identified. Electrons are believed to be transferred directly from ubiquinol (the electron donor) to the low-spin heme, and directly from the low-spin heme to the binuclear center.


Pssm-ID: 238832  Cd Length: 501  Bit Score: 819.13  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  47 WFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMRLQQFLARGGgegYLHPEHYDQIFTAHGVIMIFFVAMGLVVGLMNISV 126
Cdd:cd01662    1 WLTTVDHKRIGIMYIITAFVFFLRGGVDALLMRTQLALPGND---FLSPEHYNQIFTMHGTIMIFLFAMPLVFGLMNYLV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 127 PLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLALGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGTLLTGVN 206
Cdd:cd01662   78 PLQIGARDVAFPRLNALSFWLFLFGGLLLNASLLIGGFPDAGWFAYPPLSGLEYSPGVGVDYWILGLQFSGIGTLLGAIN 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 207 FFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWTWGHPEV 286
Cdd:cd01662  158 FIVTILKMRAPGMTLMRMPIFTWTTLVTSILILFAFPVLTAALALLELDRYFGTHFFTNALGGNPMLWQHLFWIFGHPEV 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 287 YILVLPAFGIYSEVVATFSRKTLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGVKIFSWL 366
Cdd:cd01662  238 YILILPAFGIFSEIVPTFSRKPLFGYRSMVYATVAIGFLSFGVWVHHMFTTGAGALVNAFFSIATMIIAVPTGVKIFNWL 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 367 FTMYKGRITYTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWPKMFGWR 446
Cdd:cd01662  318 FTMWRGRIRFETPMLWAIGFLVTFVIGGLTGVMLASPPADFQVHDTYFVVAHFHYVLIGGVVFPLFAGFYYWFPKMFGRM 397

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 447 LNETWGKAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYD-NPDWDPYVMIAMVGAVMIAIGIACFLMQIIVGFlqRNQR 525
Cdd:cd01662  398 LNERLGKWSFWLWFIGFNLTFFPMHILGLMGMPRRVYTYLpGPGWDPLNLISTIGAFLIAAGVLLFLINVIVSI--RKGK 475

                        490       500
                 ....*....|....*....|....*.
gi 491320759 526 LDHTGDPWDGRTLEWATSSPAPFYNF 551
Cdd:cd01662  476 RDATGDPWGARTLEWATSSPPPAYNF 501
CyoB COG0843
Heme/copper-type cytochrome/quinol oxidase, subunit 1 [Energy production and conversion];
39-578 0e+00

Heme/copper-type cytochrome/quinol oxidase, subunit 1 [Energy production and conversion];


Pssm-ID: 440605  Cd Length: 535  Bit Score: 756.20  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  39 KWGYLWNEWFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMRLQQFLArggGEGYLHPEHYDQIFTAHGVIMIFFVAMGLV 118
Cdd:COG0843    1 EWGSGWRRWLTTVDHKRIGIMYLVTAFVFLLIGGLLALLMRLQLAGP---GLGLLSPETYNQLFTMHGTIMIFFFATPFL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 119 VGLMNISVPLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLALGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGL 198
Cdd:COG0843   78 AGFGNYLVPLQIGARDMAFPRLNALSFWLYLFGGLLLLISLFVGGAADVGWTFYPPLSGLEASPGVGVDLWLLGLALFGV 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 199 GTLLTGVNFFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLI 278
Cdd:COG0843  158 GSILGGVNFIVTILKMRAPGMTLMRMPLFTWAALVTSILILLAFPVLAAALLLLLLDRSLGTHFFDPAGGGDPLLWQHLF 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 279 WTWGHPEVYILVLPAFGIYSEVVATFSRKTLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPT 358
Cdd:COG0843  238 WFFGHPEVYILILPAFGIVSEIIPTFSRKPLFGYKAMVLATVAIAFLSFLVWAHHMFTPGISPLVKAFFSIATMLIAVPT 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 359 GVKIFSWLFTMYKGRITYTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFY 438
Cdd:COG0843  318 GVKVFNWIATMWRGRIRFTTPMLFALGFIILFVIGGLTGVMLASVPLDYQVHDTYFVVAHFHYVLIGGVVFAFFAGLYYW 397

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 439 WPKMFGWRLNETWGKAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYD-NPDWDPYVMIAMVGAVMIAIGIACFLMQIIV 517
Cdd:COG0843  398 FPKMTGRMLNERLGKIHFWLWFIGFNLTFFPMHILGLLGMPRRYATYPpEPGWQPLNLISTIGAFILAVGFLLFLINLVV 477

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 491320759 518 GFLQRNqrlDHTGDPWDGRTLEWATSSPAPFYNFAHLPKINGIDTFWTDKENGVAYAKPAK 578
Cdd:COG0843  478 SLRKGP---KAGGNPWGARTLEWATPSPPPLYNFASIPVVRSRDPAYDYKKPGADFVPPAE 535
CtaD_CoxA TIGR02891
cytochrome c oxidase, subunit I; This large family represents subunit I's (CtaD, CoxA, CaaA) ...
 48-551 0e+00

cytochrome c oxidase, subunit I; This large family represents subunit I's (CtaD, CoxA, CaaA) of cytochrome c oxidases of bacterial origin. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits I-III form the functional core of the enzyme complex. Subunit I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit II and heme a of subunit I to the bimetallic center formed by heme a3 and copper B. This cytochrome c oxidase shows proton pump activity across the membrane in addition to the electron transfer. In the bacilli an apparent split (paralogism) has created a sister clade (TIGR02882) encoding subunits (QoxA) of the aa3-type quinone oxidase complex which reacts directly with quinones, bypassing the interaction with soluble cytochrome c. This model attempts to exclude these sequences, placing them between the trusted and noise cutoffs. These families, as well as archaeal and eukaryotic cytochrome c subunit I's are included within the superfamily model, pfam00115. [Energy metabolism, Electron transport]


Pssm-ID: 213748  Cd Length: 499  Bit Score: 550.29  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759   48 FTSVDHKKIGIMYIIVSVVMLLRGFADAIMMRLQqfLARGGGEgYLHPEHYDQIFTAHGVIMIFFVAMGLVVGLMNISVP 127
Cdd:TIGR02891   1 LTTVDHKRIGILYLVTAFAFFLVGGVLALLMRAQ--LATPGNT-FMDAETYNQLFTMHGTIMIFLFAIPILAGFGNYLLP 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  128 LQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLALGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGTLLTGVNF 207
Cdd:TIGR02891  78 LMIGARDMAFPRLNAFSYWLYLFGGLLLLASFFTGGAPDTGWTMYPPLSSTSGSPGVGVDLWLLGLHLLGISSILGAVNF 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  208 FVTIIKMRAPGMKLMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWTWGHPEVY 287
Cdd:TIGR02891 158 IVTILNMRAPGMTLMRMPLFVWGILVTSILILLAFPVLIAALILLLLDRLFGTHFFDPARGGDPLLWQHLFWFFGHPEVY 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  288 ILVLPAFGIYSEVVATFSRKTLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGVKIFSWLF 367
Cdd:TIGR02891 238 IIFLPAFGIISEILPTFARKPIFGYRAMVYATVAIGFLSFGVWAHHMFTTGMPPLALAFFSAATMLIAVPTGVKVFNWIA 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  368 TMYKGRITYTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWPKMFGWRL 447
Cdd:TIGR02891 318 TLWGGSIRFTTPMLFALGFIFLFVIGGLTGVMLASVPLDWQLHDTYFVVAHFHYVLVGGSVFAIFAAIYYWFPKVTGRMY 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  448 NETWGKAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTY-DNPDWDPYVMIAMVGAVMIAIGIACFLMQIIVGFLQRNqrl 526
Cdd:TIGR02891 398 NERLGRWHFWLTFVGFNLTFFPMHLLGLLGMPRRYYTYpPQMGFATLNLISTIGAFILAAGFLVFLWNLIWSLRKGP--- 474

                         490       500
                  ....*....|....*....|....*
gi 491320759  527 DHTGDPWDGRTLEWATSSPAPFYNF 551
Cdd:TIGR02891 475 KAGANPWGATTLEWTTSSPPPAHNF 499
Heme_Cu_Oxidase_I cd00919
Heme-copper oxidase subunit I. Heme-copper oxidases are transmembrane protein complexes in ...
 53-519 0e+00

Heme-copper oxidase subunit I. Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which catalyze the reduction of O2 and simultaneously pump protons across the membrane. The superfamily is diverse in terms of electron donors, subunit composition, and heme types. The number of subunits varies from three to five in bacteria and up to 13 in mammalian mitochondria. It has been proposed that Archaea acquired heme-copper oxidases through gene transfer from Gram-positive bacteria. Membership in the superfamily is defined by subunit I, which contains a heme-copper binuclear center (the active site where O2 is reduced to water) formed by a high-spin heme and a copper ion. It also contains a low-spin heme, believed to participate in the transfer of electrons to the binuclear center. Only subunit I is common to the entire superfamily. For every reduction of an O2 molecule, eight protons are taken from the inside aqueous compartment and four electrons are taken from the electron donor on the opposite side of the membrane. The four electrons and four of the protons are used in the reduction of O2; the four remaining protons are pumped across the membrane. This charge separation of four charges contributes to the electrochemical gradient used for ATP synthesis. Two proton channels, the D-pathway and K-pathway, leading to the binuclear center have been identified in subunit I of cytochrome c oxidase (CcO) and ubiquinol oxidase. A well-defined pathway for the transfer of pumped protons beyond the binuclear center has not been identified. Electron transfer occurs in two segments: from the electron donor to the low-spin heme, and from the low-spin heme to the binuclear center. The first segment can be a multi-step process and varies among the different families, while the second segment, a direct transfer, is consistent throughout the superfamily.


Pssm-ID: 238461  Cd Length: 463  Bit Score: 536.73  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  53 HKKIGIMYIIVSVVMLLRGFADAIMMRLQQFLArggGEGYLHPEHYDQIFTAHGVIMIFFVAMGLVVGLMNISVPLQIGA 132
Cdd:cd00919    1 HKDIGLLYLIFAFVALLLGGLLALLIRLELATP---GSLFLDPQLYNQLVTAHGVIMIFFFVMPAIFGGFGNLLPPLIGA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 133 RDVAFPLLNSLSFWLFAGAAGLMMVSLALGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGTLLTGVNFFVTII 212
Cdd:cd00919   78 RDLAFPRLNNLSFWLFPPGLLLLLSSVLVGGGAGTGWTFYPPLSTLSYSSGVGVDLAILGLHLAGVSSILGAINFITTIL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 213 KMRAPGMKLMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWTWGHPEVYILVLP 292
Cdd:cd00919  158 NMRAPGMTLDKMPLFVWSVLVTAILLLLALPVLAAALVMLLLDRNFGTSFFDPAGGGDPVLYQHLFWFFGHPEVYILILP 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 293 AFGIYSEVVATFSRKTLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGVKIFSWLFTMYKG 372
Cdd:cd00919  238 AFGAISEIIPTFSGKPLFGYKLMVYAFLAIGFLSFLVWAHHMFTVGLPVDTRAYFTAATMIIAVPTGIKVFNWLATLWGG 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 373 RITYTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWPKMFGWRLNETWG 452
Cdd:cd00919  318 RIRFDPPMLFALGFLFLFTIGGLTGVVLANVPLDIVLHDTYYVVAHFHYVLSGGVVFAIFAGLYYWFPKMTGRMLSEKLG 397

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 491320759 453 KAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYDnPDWDPYVMIAMVGAVMIAIGIACFLMQIIVGF 519
Cdd:cd00919  398 KIHFWLWFIGFNLTFFPMHFLGLLGMPRRYADYP-DGFAPWNFISSVGAFILGLGLLLFLGNLFLSL 463
Cyt_c_Oxidase_I cd01663
Cytochrome C oxidase subunit I. Cytochrome c oxidase (CcO), the terminal oxidase in the ...
 52-541 6.11e-161

Cytochrome C oxidase subunit I. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of prokaryotes. It catalyzes the reduction of O2 and simultaneously pumps protons across the membrane. The number of subunits varies from three to five in bacteria and up to 13 in mammalian mitochondria. Only subunits I and II are essential for function, but subunit III, which is also conserved, may play a role in assembly or oxygen delivery to the active site. Subunits I, II, and III of mammalian CcO are encoded within the mitochondrial genome and the remaining 10 subunits are encoded within the nuclear genome. Subunit I contains a heme-copper binuclear center (the active site where O2 is reduced to water) formed by a high-spin heme (heme a3) and a copper ion (CuB). It also contains a low-spin heme (heme a), believed to participate in the transfer of electrons to the binuclear center. For every reduction of an O2 molecule, eight protons are taken from the inside aqueous compartment and four electrons are taken from cytochrome c on the opposite side of the membrane. The four electrons and four of the protons are used in the reduction of O2; the four remaining protons are pumped across the membrane. This charge separation of four charges contributes to the electrochemical gradient used for ATP synthesis. Two proton channels, the D-pathway and K-pathway, leading to the binuclear center have been identified in subunit I. A well-defined pathway for the transfer of pumped protons beyond the binuclear center has not been identified. Electrons are transferred from cytochrome c (the electron donor) to heme a via the CuA binuclear site in subunit II, and directly from heme a to the binuclear center.


Pssm-ID: 238833  Cd Length: 488  Bit Score: 471.20  E-value: 6.11e-161
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  52 DHKKIGIMYIIVSVVMLLRGFADAIMMRLQQFlarGGGEGYLHPEHYDQIFTAHGVIMIFFVAM-GLVVGLMNISVPLQI 130
Cdd:cd01663    2 NHKDIGTLYLIFGLWSGLVGTSLSLLIRLELS---QPGSQLGNDQLYNVIVTAHALIMIFFMVMpALIGGFGNWLVPLMI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 131 GARDVAFPLLNSLSFWLFAGAAGLMMVSLALGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGTLLTGVNFFVT 210
Cdd:cd01663   79 GAPDMAFPRLNNLSFWLLPPSLLLLLLSALVEGGAGTGWTVYPPLSSILAHSGPSVDLAIFSLHLAGISSILGAINFITT 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 211 IIKMRAPGMKLMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWTWGHPEVYILV 290
Cdd:cd01663  159 IFNMRAPGMTLEKMPLFVWSVLITAFLLLLSLPVLAGAITMLLTDRNFNTSFFDPAGGGDPILYQHLFWFFGHPEVYILI 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 291 LPAFGIYSEVVATFS-RKTLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGVKIFSWLFTM 369
Cdd:cd01663  239 LPGFGIISHIISTFSgKKPVFGYLGMVYAMLSIGILGFIVWAHHMFTVGLDVDTRAYFTAATMIIAVPTGIKVFSWLATM 318

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 370 YKGRITYTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWPKMFGWRLNE 449
Cdd:cd01663  319 WGGSIKFETPMLWALGFIFLFTIGGLTGVVLANSSLDIALHDTYYVVAHFHYVLSMGAVFAIFAGFYYWFPKITGLSYNE 398

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 450 TWGKAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYdnPD----WDpyvMIAMVGAVMIAIGIACFLMQIIVGFLQRNQR 525
Cdd:cd01663  399 TLGKIHFWLMFIGVNLTFFPQHFLGLAGMPRRYPDY--PDayagWN---MISSIGSLISFVSVLLFLFIVWESFVSGRKV 473

                        490
                 ....*....|....*.
gi 491320759 526 LDHTGDPWDgrTLEWA 541
Cdd:cd01663  474 IFNVGEGST--SLEWT 487
COX1 pfam00115
Cytochrome C and Quinol oxidase polypeptide I; Cytochrome c oxidase (E.C:7.1.1.9) is a key ...
 55-503 3.05e-143

Cytochrome C and Quinol oxidase polypeptide I; Cytochrome c oxidase (E.C:7.1.1.9) is a key enzyme in aerobic metabolism. Proton pumping haem-copper oxidases represent the terminal, energy-transfer enzymes of respiratory chains in prokaryotes and eukaryotes. The CuB-haem a3 (or haem o) binuclear centre, associated with the largest subunit I of cytochrome c and ubiquinol oxidases (E.C:1.10.3.11), is directly involved in the coupling between dioxygen reduction and proton pumping. Some terminal oxidases generate a transmembrane proton gradient across the plasma membrane (prokaryotes) or the mitochondrial inner membrane (eukaryotes). The enzyme complex consists of 3-4 subunits (prokaryotes) up to 13 polypeptides (mammals) of which only the catalytic subunit (equivalent to mammalian subunit I (COXI) is found in all haem-copper respiratory oxidases. The presence of a bimetallic centre (formed by a high-spin haem and copper B) as well as a low-spin haem, both ligated to six conserved histidine residues near the outer side of four transmembrane spans within CO I is common to all family members.


Pssm-ID: 459678  Cd Length: 432  Bit Score: 423.91  E-value: 3.05e-143
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759   55 KIGIMYIIVSVVMLLRGFADAIMMRLQQFLArggGEGYLHPEHYDQIFTAHGVIMIFFVAMGLVVGLMNISVPLQIGARD 134
Cdd:pfam00115   1 RIGLLYLVTALVWFLVGGLLGLLIRLQLAFP---GLNFLSPLTYNQLRTLHGNLMIFWFATPFLFGFGNYLVPLMIGARD 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  135 VAFPLLNSLSFWLFAGAAGLMMVSLAlgeFAATGWMAYPPLsgieyspgVGMDYYIWALQISGLGTLLTGVNFFVTIIKM 214
Cdd:pfam00115  78 MAFPRLNALSFWLVVLGAVLLLASFG---GATTGWTEYPPL--------VGVDLWYIGLLLAGVSSLLGAINFIVTILKR 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  215 RAPGMKlMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGfhfftnDMGGSPMLYVNLIWTWGHPEVYILVLPAF 294
Cdd:pfam00115 147 RAPGMT-LRMPLFVWAILATAILILLAFPVLAAALLLLLLDRSLG------AGGGDPLLDQHLFWWFGHPEVYILILPAF 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  295 GIYSEVVATFSRKTLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGVKIFSWLFTMYKGRI 374
Cdd:pfam00115 220 GIIYYILPKFAGRPLFGYKLSVLAFWLIAFLGFLVWAHHLFTTGLPPWLQALFSVFSMLIAVPSGVKVFNWLATLWGGWI 299

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  375 T-YTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWPKMFGWRLNETWGK 453
Cdd:pfam00115 300 RfRTTPMLFFLGFAFLFIIGGLTGVMLALPPVNYYVHDTYFVVAHFHYVLFGGVVFALFGGIYYWLPKLTGRMYSEKLGK 379

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 491320759  454 AAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYDN---PDWDPYVMIAMVGAVM 503
Cdd:pfam00115 380 LHFWLLFIGFNLTFFPMHILGLLGMPRRYAPPFIetvPAFQPLNWIRTIGGVL 432
COX1 MTH00223
cytochrome c oxidase subunit I; Provisional
 46-557 4.36e-131

cytochrome c oxidase subunit I; Provisional


Pssm-ID: 177260  Cd Length: 512  Bit Score: 395.89  E-value: 4.36e-131
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  46 EWFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMRLQqfLARGGGegYLHPEH-YDQIFTAHGVIMIFFVAMGLVVG-LMN 123
Cdd:MTH00223   2 RWLFSTNHKDIGTLYLIFGMWSGLVGTSLSLLIRAE--LGQPGA--LLGDDQlYNVIVTAHAFVMIFFLVMPMMIGgFGN 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 124 ISVPLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLALGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGTLLT 203
Cdd:MTH00223  78 WLVPLMLGAPDMAFPRLNNMSFWLLPPSLYLLLSSSAVESGVGTGWTVYPPLSSNLAHAGPSVDLAIFSLHLAGVSSILG 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 204 GVNFFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWTWGH 283
Cdd:MTH00223 158 AINFITTIINMRSPGMQLERLPLFVWSVKVTAFLLLLSLPVLAGAITMLLTDRNFNTSFFDPAGGGDPILYQHLFWFFGH 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 284 PEVYILVLPAFGIYSEVVATFSRK-TLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGVKI 362
Cdd:MTH00223 238 PEVYILILPGFGMISHIVSHYSSKkEVFGTLGMIYAMLSIGVLGFIVWAHHMFTVGMDVDTRAYFTAATMIIAVPTGIKV 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 363 FSWLFTMYKGRITYTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWPKM 442
Cdd:MTH00223 318 FSWLATIYGSKIKYEAPMLWALGFIFLFTVGGLTGIILSNSSLDIMLHDTYYVVAHFHYVLSMGAVFALFAGFNHWFPLF 397

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 443 FGWRLNETWGKAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYdnPD-WDPYVMIAMVGAVMIAIGIACFLMQIIVGFLQ 521
Cdd:MTH00223 398 TGVTLHRRWAKAHFFLMFLGVNLTFFPQHFLGLAGMPRRYSDY--PDcYTKWNQVSSFGSMISFVSVLFFMFIVWEAFVS 475

                        490       500       510
                 ....*....|....*....|....*....|....*.
gi 491320759 522 RNQRLDHTGDPwdgRTLEWATSSPAPFYNFAHLPKI 557
Cdd:MTH00223 476 QRSVVWSGHLS---TSLEWDNLLPADFHNNSETGAL 508
COX1 MTH00167
cytochrome c oxidase subunit I; Provisional
 45-555 2.39e-126

cytochrome c oxidase subunit I; Provisional


Pssm-ID: 177222  Cd Length: 512  Bit Score: 383.64  E-value: 2.39e-126
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  45 NEWFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMRLQqfLARGG---GEGYLhpehYDQIFTAHGVIMIFFVAMGLVVG- 120
Cdd:MTH00167   4 NRWLFSTNHKDIGTLYFIFGAWAGMVGTALSLLIRAE--LSQPGsllGDDQI----YNVIVTAHAFVMIFFMVMPIMIGg 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 121 LMNISVPLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLALGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGT 200
Cdd:MTH00167  78 FGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSLLLLLASSGVEAGAGTGWTVYPPLAGNLAHAGASVDLAIFSLHLAGVSS 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 201 LLTGVNFFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWT 280
Cdd:MTH00167 158 ILGSINFITTIINMKPPGITQYQTPLFVWSILVTTILLLLSLPVLAAAITMLLTDRNLNTTFFDPAGGGDPILYQHLFWF 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 281 WGHPEVYILVLPAFGIYSEVVATFS-RKTLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTG 359
Cdd:MTH00167 238 FGHPEVYILILPGFGMISHIVVYYSgKKEPFGYMGMVWAMMAIGLLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAVPTG 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 360 VKIFSWLFTMYKGRITYTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYW 439
Cdd:MTH00167 318 IKVFSWLATLHGGKIKWETPMLWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMAGFTHWF 397

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 440 PKMFGWRLNETWGKAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYdnPD-WDPYVMIAMVGAVMIAIGIACFLMQIIVG 518
Cdd:MTH00167 398 PLFTGLTLNETWTKIHFFVMFIGVNLTFFPQHFLGLAGMPRRYSDY--PDaYTLWNVVSSIGSLISLVAVILFLFIIWEA 475

                        490       500       510
                 ....*....|....*....|....*....|....*..
gi 491320759 519 FLQRNQRLDHTGdpwDGRTLEWATSSPAPFYNFAHLP 555
Cdd:MTH00167 476 FSSKRKLLPVEL---TSTNVEWLHGCPPPHHTWEEPP 509
COX1 MTH00153
cytochrome c oxidase subunit I; Provisional
 45-558 2.00e-125

cytochrome c oxidase subunit I; Provisional


Pssm-ID: 177210  Cd Length: 511  Bit Score: 381.14  E-value: 2.00e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  45 NEWFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMRLQqfLARGG---GEGYLhpehYDQIFTAHGVIMIFFVAMGLVVG- 120
Cdd:MTH00153   2 NKWLFSTNHKDIGTLYFIFGAWSGMVGTSLSLLIRAE--LGQPGsliGDDQI----YNVIVTAHAFIMIFFMVMPIMIGg 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 121 LMNISVPLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLALGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGT 200
Cdd:MTH00153  76 FGNWLVPLMLGAPDMAFPRMNNMSFWLLPPSLTLLLSSSMVESGAGTGWTVYPPLSSNIAHSGASVDLAIFSLHLAGISS 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 201 LLTGVNFFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWT 280
Cdd:MTH00153 156 ILGAINFITTIINMRSKGMTLDRMPLFVWSVLITAILLLLSLPVLAGAITMLLTDRNLNTSFFDPAGGGDPILYQHLFWF 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 281 WGHPEVYILVLPAFGIYSEVVATFS-RKTLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTG 359
Cdd:MTH00153 236 FGHPEVYILILPGFGMISHIISQESgKKETFGTLGMIYAMLAIGLLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAVPTG 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 360 VKIFSWLFTMYKGRITYTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYW 439
Cdd:MTH00153 316 IKIFSWLATLHGSQINYSPSLLWALGFVFLFTIGGLTGVVLANSSIDIILHDTYYVVAHFHYVLSMGAVFAIMGGFIHWF 395

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 440 PKMFGWRLNETWGKAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYdnPD----WDpyvMIAMVGAVMIAIGIACFLMQI 515
Cdd:MTH00153 396 PLFTGLTMNPKWLKIQFFIMFIGVNLTFFPQHFLGLAGMPRRYSDY--PDaytsWN---VISSIGSTISLISILFFIFII 470

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|...
gi 491320759 516 IVGFLQRNQRLDHTGDPwdgRTLEWATSSPAPFYNFAHLPKIN 558
Cdd:MTH00153 471 WESMISKRPVLFSLNLS---SSIEWLQNLPPAEHSYSELPLLT 510
COX1 MTH00116
cytochrome c oxidase subunit I; Provisional
 45-551 3.33e-122

cytochrome c oxidase subunit I; Provisional


Pssm-ID: 177177  Cd Length: 515  Bit Score: 372.89  E-value: 3.33e-122
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  45 NEWFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMRLQqfLARGGgEGYLHPEHYDQIFTAHGVIMIFFVAMGLVVG-LMN 123
Cdd:MTH00116   4 TRWLFSTNHKDIGTLYLIFGAWAGMVGTALSLLIRAE--LGQPG-TLLGDDQIYNVIVTAHAFVMIFFMVMPIMIGgFGN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 124 ISVPLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLALGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGTLLT 203
Cdd:MTH00116  81 WLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSTVEAGAGTGWTVYPPLAGNLAHAGASVDLAIFSLHLAGVSSILG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 204 GVNFFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWTWGH 283
Cdd:MTH00116 161 AINFITTCINMKPPAMSQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGH 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 284 PEVYILVLPAFGIYSEVVATFS-RKTLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGVKI 362
Cdd:MTH00116 241 PEVYILILPGFGIISHIVTYYAgKKEPFGYMGMVWAMLSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGIKV 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 363 FSWLFTMYKGRITYTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWPKM 442
Cdd:MTH00116 321 FSWLATLHGGTIKWDPPMLWALGFIFLFTIGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMAGFTHWFPLF 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 443 FGWRLNETWGKAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYDnpdwDPYVMIAMVGAVMIAIGIACFLMQIIVGFLQR 522
Cdd:MTH00116 401 TGYTLHQTWTKAQFGVMFTGVNLTFFPQHFLGLAGMPRRYSDYP----DAYTLWNTISSIGSLISMTAVIMLMFIIWEAF 476

                        490       500
                 ....*....|....*....|....*....
gi 491320759 523 NQRLDHTGDPWDGRTLEWATSSPAPFYNF 551
Cdd:MTH00116 477 SSKRKVLQPELTTTNIEWIHGCPPPYHTF 505
COX1 MTH00142
cytochrome c oxidase subunit I; Provisional
 45-559 7.84e-120

cytochrome c oxidase subunit I; Provisional


Pssm-ID: 214431  Cd Length: 511  Bit Score: 366.74  E-value: 7.84e-120
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  45 NEWFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMRLQqfLARGG---GEGYLhpehYDQIFTAHGVIMIFFVAMGLVVG- 120
Cdd:MTH00142   2 MRWLFSTNHKDIGTLYFLFGAWAGMVGTGLSLLIRAE--LGQPGsllGDDQL----YNVIVTAHAFVMIFFMVMPVMIGg 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 121 LMNISVPLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLALGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGT 200
Cdd:MTH00142  76 FGNWLVPLMLGAPDMAFPRMNNMSFWLLPPALLLLLSSAAVESGAGTGWTVYPPLSSNLAHSGGSVDLAIFSLHLAGVSS 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 201 LLTGVNFFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWT 280
Cdd:MTH00142 156 ILGAINFITTVINMRAGGMKFERVPLFVWSVKITAILLLLSLPVLAGAITMLLTDRNFNTSFFDPAGGGDPILYQHLFWF 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 281 WGHPEVYILVLPAFGIYSEVVATFS-RKTLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTG 359
Cdd:MTH00142 236 FGHPEVYILILPGFGMISHIINHYSgKKEVFGTLGMIYAMLSIGLLGFIVWAHHMFTVGMDVDTRAYFTAATMVIAVPTG 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 360 VKIFSWLFTMYKGRITYTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYW 439
Cdd:MTH00142 316 IKVFSWLATLHGSKVKYEPPMLWALGFIFLFTVGGLTGIVLANSSLDVVLHDTYYVVAHFHYVLSMGAVFALFAGFIHWF 395

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 440 PKMFGWRLNETWGKAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYdnPD-WDPYVMIAMVGAVMIAIGIACFLMQIIVG 518
Cdd:MTH00142 396 PLFTGLTLNPRWLKAHFYTMFIGVNLTFFPQHFLGLAGMPRRYSDY--PDaYTTWNVVSSLGSMISFIAVLMFVFIVWES 473

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|.
gi 491320759 519 FLqrNQRLDHTGdPWDGRTLEWATSSPAPFYNFAHLPKING 559
Cdd:MTH00142 474 FV--SQRLVMWS-SHLSTSLEWSHRLPPDFHTYDELPILVV 511
COX1 MTH00184
cytochrome c oxidase subunit I; Provisional
 47-555 2.31e-118

cytochrome c oxidase subunit I; Provisional


Pssm-ID: 177235  Cd Length: 519  Bit Score: 363.38  E-value: 2.31e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  47 WFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMRLQqFLARGGGEGYLHPehYDQIFTAHGVIMIFFVAMGLVVG-LMNIS 125
Cdd:MTH00184   8 WLFSTNHKDIGTLYLLFGAFAGMIGTAFSMLIRLE-LSAPGSMLGDDHL--YNVIVTAHAFVMIFFLVMPVMIGgFGNWF 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 126 VPLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLALGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGTLLTGV 205
Cdd:MTH00184  85 VPLYIGAPDMAFPRLNNISFWLLPPALTLLLGSAFVEQGAGTGWTVYPPLSSIQAHSGGSVDMAIFSLHLAGISSILGAM 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 206 NFFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWTWGHPE 285
Cdd:MTH00184 165 NFITTIFNMRAPGITMDRMPLFVWSILVTTFLLLLSLPVLAGAITMLLTDRNFNTTFFDPAGGGDPILYQHLFWFFGHPE 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 286 VYILVLPAFGIYSEVVATFS-RKTLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGVKIFS 364
Cdd:MTH00184 245 VYILILPGFGIISQIIPTFAaKKQIFGYLGMVYAMVSIGILGFIVWAHHMFTVGMDVDTRAYFTAATMIIAVPTGIKIFS 324

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 365 WLFTMYKGRITYTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWPKMFG 444
Cdd:MTH00184 325 WIATIFGGSLRLDTPMLWAIGFVFLFTMGGLTGIVLANSSLDVVLHDTYYVVAHFHYVLSMGAVFAIFGGFYYWFGKITG 404

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 445 WRLNETWGKAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYDNpDWDPYVMIAMVGAVMIAIGIACFLMQIIVGFLQRNQ 524
Cdd:MTH00184 405 YCYNEVYGKIHFWLMFIGVNLTFFPQHFLGLAGLPRRYSDFHD-SFAGWNQISSLGSVISIVGVVWFIYIVYDAYVREIK 483

                        490       500       510
                 ....*....|....*....|....*....|.
gi 491320759 525 RLDHTGDPWDGRTLEWATSSPAPFYNFAHLP 555
Cdd:MTH00184 484 FVGWVEDSGHYPSLEWAQTSPPAHHTYNELP 514
COX1 MTH00182
cytochrome c oxidase subunit I; Provisional
 44-563 2.30e-116

cytochrome c oxidase subunit I; Provisional


Pssm-ID: 214451  Cd Length: 525  Bit Score: 358.36  E-value: 2.30e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  44 WNEWFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMRLQqFLARGGGEGYLHpeHYDQIFTAHGVIMIFFVAMGLVVG-LM 122
Cdd:MTH00182   5 LTRWVFSTNHKDIGTLYLVFGAGAGMIGTAFSMLIRLE-LSAPGAMLGDDH--LYNVIVTAHAFIMIFFLVMPVMIGgFG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 123 NISVPLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLALGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGTLL 202
Cdd:MTH00182  82 NWLVPLYIGAPDMAFPRLNNISFWLLPPALILLLGSAFVEQGAGTGWTVYPPLSSIQAHSGGAVDMAIFSLHLAGVSSIL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 203 TGVNFFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWTWG 282
Cdd:MTH00182 162 GAINFITTIFNMRAPGVTFNRLPLFVWSILITAFLLLLSLPVLAGAITMLLTDRNFNTTFFDPAGGGDPILFQHLFWFFG 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 283 HPEVYILVLPAFGIYSEVVATFS-RKTLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGVK 361
Cdd:MTH00182 242 HPEVYILILPGFGMISQIIPTFVaKKQIFGYLGMVYAMLSIGILGFIVWAHHMFTVGMDVDTRAYFTAATMIIAVPTGIK 321

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 362 IFSWLFTMYKGRITYTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWPK 441
Cdd:MTH00182 322 VFSWLATIYGGTLRLDTPMLWAMGFVFLFTLGGLTGVVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIFGGFYYWFGK 401

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 442 MFGWRLNETWGKAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYDN--PDWDpyvMIAMVGAVMIAIGIACFLMQIIVGF 519
Cdd:MTH00182 402 ITGYCYNELYGKIHFWLMFIGVNLTFFPQHFLGLAGFPRRYSDFADafAGWN---LVSSLGSIISIVGVVWFIYIIYDAY 478

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*..
gi 491320759 520 LQRNQRL---DHTGDPWDgrTLEWATSSPAPFYNFAHLPKINGIDTF 563
Cdd:MTH00182 479 VREEKFIgwkEGTGESWA--SLEWVHSSPPLFHTYNELPFVYKSKLS 523
COX1 MTH00183
cytochrome c oxidase subunit I; Provisional
 47-551 1.11e-112

cytochrome c oxidase subunit I; Provisional


Pssm-ID: 177234  Cd Length: 516  Bit Score: 348.45  E-value: 1.11e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  47 WFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMR--LQQFLARGGGEgylhpEHYDQIFTAHGVIMIFFVAMGLVVG-LMN 123
Cdd:MTH00183   6 WFFSTNHKDIGTLYLVFGAWAGMVGTALSLLIRaeLSQPGALLGDD-----QIYNVIVTAHAFVMIFFMVMPIMIGgFGN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 124 ISVPLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLALGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGTLLT 203
Cdd:MTH00183  81 WLIPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSGVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 204 GVNFFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWTWGH 283
Cdd:MTH00183 161 AINFITTIINMKPPAISQYQTPLFVWAVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGH 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 284 PEVYILVLPAFGIYSEVVATFS-RKTLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGVKI 362
Cdd:MTH00183 241 PEVYILILPGFGMISHIVAYYSgKKEPFGYMGMVWAMMAIGLLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKV 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 363 FSWLFTMYKGRITYTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWPKM 442
Cdd:MTH00183 321 FSWLATLHGGSIKWETPLLWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMAAFVHWFPLF 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 443 FGWRLNETWGKAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYdnPD-WDPYVMIAMVGAVMIAIGIACFLMQIIVGFLQ 521
Cdd:MTH00183 401 SGYTLHSTWTKIHFGVMFVGVNLTFFPQHFLGLAGMPRRYSDY--PDaYTLWNTVSSIGSLISLVAVIMFLFILWEAFAA 478

                        490       500       510
                 ....*....|....*....|....*....|..
gi 491320759 522 RN--QRLDHTgdpwdGRTLEWATSSPAPFYNF 551
Cdd:MTH00183 479 KRevLSVELT-----STNVEWLHGCPPPYHTF 505
COX1 MTH00077
cytochrome c oxidase subunit I; Provisional
 43-551 9.81e-112

cytochrome c oxidase subunit I; Provisional


Pssm-ID: 214419  Cd Length: 514  Bit Score: 345.77  E-value: 9.81e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  43 LWNEWFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMRLQqfLARGGGEgYLHPEHYDQIFTAHGVIMIFFVAMGLVVG-L 121
Cdd:MTH00077   2 MITRWLFSTNHKDIGTLYLVFGAWAGMVGTALSLLIRAE--LSQPGTL-LGDDQIYNVIVTAHAFVMIFFMVMPIMIGgF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 122 MNISVPLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLALGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGTL 201
Cdd:MTH00077  79 GNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSGVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSI 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 202 LTGVNFFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWTW 281
Cdd:MTH00077 159 LGAINFITTSINMKPPSMSQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPVLYQHLFWFF 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 282 GHPEVYILVLPAFGIYSEVVATFS-RKTLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGV 360
Cdd:MTH00077 239 GHPEVYILILPGFGMISHIVTYYSaKKEPFGYMGMVWAMMSIGLLGFIVWAHHMFTVDLNVDTRAYFTSATMIIAIPTGV 318

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 361 KIFSWLFTMYKGRITYTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWP 440
Cdd:MTH00077 319 KVFSWLATMHGGAIKWDAAMLWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFP 398

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 441 KMFGWRLNETWGKAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYDnpdwDPYVMIAMVGAVMIAIGIACFLMQIIVGFL 520
Cdd:MTH00077 399 LFSGYTLHSTWSKIHFGVMFIGVNLTFFPQHFLGLAGMPRRYSDYP----DAYTLWNTVSSIGSLISLVAVIMMMFIIWE 474

                        490       500       510
                 ....*....|....*....|....*....|.
gi 491320759 521 QRNQRLDHTGDPWDGRTLEWATSSPAPFYNF 551
Cdd:MTH00077 475 AFSSKREVLTTELTSTNIEWLHGCPPPYHTF 505
COX1 MTH00079
cytochrome c oxidase subunit I; Provisional
 47-485 4.68e-111

cytochrome c oxidase subunit I; Provisional


Pssm-ID: 177148  Cd Length: 508  Bit Score: 343.97  E-value: 4.68e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  47 WFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMRLQqfLARGG---GEGYLhpehYDQIFTAHGVIMIFFVAM-GLVVGLM 122
Cdd:MTH00079   7 WLESSNHKDIGTLYFLFGLWSGMVGTSLSLIIRLE--LSKPGlllGNGQL----YNSVITAHAILMIFFMVMpSMIGGFG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 123 NISVPLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLALGEFAATGWMAYPPLSgIEYSPGVGMDYYIWALQISGLGTLL 202
Cdd:MTH00079  81 NWMLPLMLGAPDMSFPRLNNLSFWLLPTSLFLILDSCFVDMGPGTSWTVYPPLS-TLGHPGSSVDLAIFSLHCAGISSIL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 203 TGVNFFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWTWG 282
Cdd:MTH00079 160 GGINFMVTTKNLRSSSISLEHMSLFVWTVFVTVFLLVLSLPVLAGAITMLLTDRNLNTSFFDPSTGGNPLLYQHLFWFFG 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 283 HPEVYILVLPAFGIYSEVVATFS-RKTLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGVK 361
Cdd:MTH00079 240 HPEVYILILPAFGIISQSTLYLTgKKEVFGSLGMVYAILSIGLIGCVVWAHHMYTVGMDLDSRAYFTAATMVIAVPTGVK 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 362 IFSWLFTMYKGRITYTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWPK 441
Cdd:MTH00079 320 VFSWLATLFGMKMKFQPLLLWVLGFIFLFTIGGLTGVILSNSSLDIILHDTYYVVSHFHYVLSLGAVFGIFTGISLWWPF 399

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....
gi 491320759 442 MFGWRLNETWGKAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTY 485
Cdd:MTH00079 400 MTGIVYDKLMMSAVFFLMFVGVNLTFFPLHFAGLHGMPRKYLDY 443
COX1 MTH00007
cytochrome c oxidase subunit I; Validated
 47-550 1.41e-110

cytochrome c oxidase subunit I; Validated


Pssm-ID: 133649  Cd Length: 511  Bit Score: 342.65  E-value: 1.41e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  47 WFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMRLQqfLARGGGegYLHPEH-YDQIFTAHGVIMIFFVAMGLVVG-LMNI 124
Cdd:MTH00007   3 WLYSTNHKDIGTLYFILGVWGGLLGTSMSLLIRIE--LGQPGA--FLGSDQlYNTIVTAHAFLMIFFLVMPVFIGgFGNW 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 125 SVPLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLALGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGTLLTG 204
Cdd:MTH00007  79 LVPLMLGAPDMAFPRLNNMSFWLLPPALILLVSSAAVEKGVGTGWTVYPPLASNLAHAGPSVDLAIFSLHLAGVSSILGA 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 205 VNFFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWTWGHP 284
Cdd:MTH00007 159 INFITTVINMRWKGLRLERIPLFVWAVVITVVLLLLSLPVLAGAITMLLTDRNLNTSFFDPAGGGDPILYQHLFWFFGHP 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 285 EVYILVLPAFGIYSEVVATFSRK-TLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGVKIF 363
Cdd:MTH00007 239 EVYILILPGFGAISHIVTHYAGKlEPFGTLGMIYAMLGIGVLGFIVWAHHMFTVGMDVDTRAYFTAATMIIAVPTGIKVF 318

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 364 SWLFTMYKGRITYTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWPKMF 443
Cdd:MTH00007 319 SWLATIHGSPIKYETPMLWALGFIFLFTTGGLTGIVLSNSSLDIILHDTYYVVAHFHYVLSMGAVFAIFAAFNHWFPLFT 398

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 444 GWRLNETWGKAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYdnPD-WDPYVMIAMVGAVMIAIGIACFLMQIIVGFLQR 522
Cdd:MTH00007 399 GLTLHDRWAKAHFFLMFLGVNLTFFPQHFLGLSGMPRRYSDY--PDaYTKWNVVSSFGSMLSFVALLLFIFILWEAFSAQ 476

                        490       500
                 ....*....|....*....|....*...
gi 491320759 523 NQRLdhtGDPWDGRTLEWATSSPAPFYN 550
Cdd:MTH00007 477 RGVI---ASPHMSSSLEWQDTLPLDFHN 501
COX1 MTH00103
cytochrome c oxidase subunit I; Validated
 45-558 2.21e-110

cytochrome c oxidase subunit I; Validated


Pssm-ID: 177165  Cd Length: 513  Bit Score: 342.25  E-value: 2.21e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  45 NEWFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMRlqqflARGGGEGYL--HPEHYDQIFTAHGVIMIFFVAMGLVVG-L 121
Cdd:MTH00103   4 NRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIR-----AELGQPGTLlgDDQIYNVIVTAHAFVMIFFMVMPIMIGgF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 122 MNISVPLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLALGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGTL 201
Cdd:MTH00103  79 GNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSI 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 202 LTGVNFFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWTW 281
Cdd:MTH00103 159 LGAINFITTIINMKPPAMSQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFF 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 282 GHPEVYILVLPAFGIYSEVVATFS-RKTLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGV 360
Cdd:MTH00103 239 GHPEVYILILPGFGMISHIVTYYSgKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGV 318

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 361 KIFSWLFTMYKGRITYTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWP 440
Cdd:MTH00103 319 KVFSWLATLHGGNIKWSPAMLWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFP 398

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 441 KMFGWRLNETWGKAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYDnpdwDPYVMIAMVGAVMIAIGIACFLMQIIVGFL 520
Cdd:MTH00103 399 LFSGYTLNDTWAKIHFTIMFVGVNMTFFPQHFLGLSGMPRRYSDYP----DAYTTWNTVSSMGSFISLTAVMLMIFMIWE 474

                        490       500       510
                 ....*....|....*....|....*....|....*...
gi 491320759 521 QRNQRLDHTGDPWDGRTLEWATSSPAPFYNFAHLPKIN 558
Cdd:MTH00103 475 AFASKREVLTVELTTTNLEWLHGCPPPYHTFEEPTYVK 512
COX1 MTH00026
cytochrome c oxidase subunit I; Provisional
 47-559 1.57e-106

cytochrome c oxidase subunit I; Provisional


Pssm-ID: 164599  Cd Length: 534  Bit Score: 333.13  E-value: 1.57e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  47 WFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMRLQqfLARGGGegYLHPEH-YDQIFTAHGVIMIFFVAMGLVVG-LMNI 124
Cdd:MTH00026   7 WFFSCNHKDIGSLYLVFGALSGAIGTAFSMLIRLE--LSSPGS--MLGDDHlYNVIVTAHAFVMIFFLVMPTMIGgFGNW 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 125 SVPLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLALGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGTLLTG 204
Cdd:MTH00026  83 FVPLMIGAPDMAFPRLNNISFWLLPPALFLLLGSSLVEQGAGTGWTVYPPLASIQAHSGGSVDMAIFSLHLAGLSSILGA 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 205 VNFFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWTWGHP 284
Cdd:MTH00026 163 MNFITTVMNMRTPGMTMSRIPLFVWSVFITAILLLLSLPVLAGAITMLLTDRNFNTTFFDPAGGGDPILYQHLFWFFGHP 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 285 EVYILVLPAFGIYSEVVATFS-RKTLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGVKIF 363
Cdd:MTH00026 243 EVYILILPGFGIISQILSLFSyKKQIFGYLGMVYAMLAIGVLGFIVWAHHMYVVGMDVDTRAYFTAATMIIAVPTGIKIF 322

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 364 SWLFTMY-KGR-ITYTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWPK 441
Cdd:MTH00026 323 SWLATVSgSGRnLIFTTPMAWALGFIFLFTIGGLTGIVLSNSSLDILLHDTYYVVAHFHFVLSMGAVFAIFGGFYLWFGK 402

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 442 MFGWRLNETWGKAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYDNpDWDPYVMIAMVGAVMIAIGIACFLMQII----- 516
Cdd:MTH00026 403 ITGYAYKDIYGLIHFWLMFIGVNITFFPQHFLGLAGLPRRYADYPD-NFEDFNQISSFGSIISIIAVIWFIVVIFdayyr 481

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*...
gi 491320759 517 -----VGFLQRNQRLDHTGDPWDGRTLEWATSSPAPFYNFAHLPKING 559
Cdd:MTH00026 482 eepfdINIMAKGPLIPFSCQPAHFDTLEWSLTSPPEHHTYNELPYIVG 529
COX1 MTH00037
cytochrome c oxidase subunit I; Provisional
 45-547 8.34e-106

cytochrome c oxidase subunit I; Provisional


Pssm-ID: 177112  Cd Length: 517  Bit Score: 330.64  E-value: 8.34e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  45 NEWFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMRLQqfLARGGGegYLHPEH-YDQIFTAHGVIMIFFVAMGLVVG-LM 122
Cdd:MTH00037   4 SRWLFSTNHKDIGTLYLIFGAWAGMVGTAMSVIIRTE--LAQPGS--LLQDDQiYNVIVTAHALVMIFFMVMPIMIGgFG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 123 NISVPLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLALGEFAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGTLL 202
Cdd:MTH00037  80 NWLIPLMIGAPDMAFPRMNNMSFWLIPPSFLLLLASAGVESGAGTGWTIYPPLSSNIAHAGGSVDLAIFSLHLAGASSIL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 203 TGVNFFVTIIKMRAPGMKLMDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWTWG 282
Cdd:MTH00037 160 ASINFITTIINMRTPGMTFDRLPLFVWSVFITAFLLLLSLPVLAGAITMLLTDRNINTTFFDPAGGGDPILFQHLFWFFG 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 283 HPEVYILVLPAFGIYSEVVATFSRKTL-FGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGVK 361
Cdd:MTH00037 240 HPEVYILILPGFGMISHVIAHYSGKQEpFGYLGMVYAMIAIGILGFLVWAHHMFTVGMDVDTRAYFTAATMIIAVPTGIK 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 362 IFSWLFTMYKGRITYTTPMLWTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWPK 441
Cdd:MTH00037 320 VFSWMATLQGSNLRWETPLLWALGFVFLFTIGGLTGIVLANSSIDVVLHDTYYVVAHFHYVLSMGAVFAIFAGFTHWFPL 399

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 442 MFGWRLNETWGKAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYdnPD-WDPYVMIAMVGAVMIAIGIACFLMQIIVGFL 520
Cdd:MTH00037 400 FSGVSLHPLWSKVHFFLMFIGVNLTFFPQHFLGLAGMPRRYSDY--PDaYTLWNTVSSIGSTISLVATLFFLFLIWEAFA 477

                        490       500
                 ....*....|....*....|....*..
gi 491320759 521 QRNQrldHTGDPWDGRTLEWATSSPAP 547
Cdd:MTH00037 478 SQRE---VISPEFSSSSLEWQYSSFPP 501
COX1 MTH00048
cytochrome c oxidase subunit I; Provisional
 47-516 1.85e-92

cytochrome c oxidase subunit I; Provisional


Pssm-ID: 177123  Cd Length: 511  Bit Score: 295.43  E-value: 1.85e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  47 WFTSVDHKKIGIMYIIVSVVMLLRGFADAIMMRLQQFlargggEGYLH---PEHYDQIFTAHGVIMIFFVAMG-LVVGLM 122
Cdd:MTH00048   7 WLFTLDHKRIGVIYTLLGVWSGFVGLSLSLLIRLNFL------DPYYNvisLDVYNFLITNHGIIMIFFFLMPvLIGGFG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 123 NISVPLQIGARDVAFPLLNSLSFWLFAGAAGLMMVSLALGefAATGWMAYPPLSGIEYSPGVGMDYYIWALQISGLGTLL 202
Cdd:MTH00048  81 NYLLPLLLGLSDLNLPRLNALSAWLLVPSIVFLLLSMCLG--AGVGWTFYPPLSSSLFSSSWGVDFLMFSLHLAGVSSLF 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 203 TGVNFFVTIIKMRAPGMKLmDMPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNDMGGSPMLYVNLIWTWG 282
Cdd:MTH00048 159 GSINFICTIYSAFMTNVFS-RTSIILWSYLFTSILLLLSLPVLAAAITMLLFDRNFGSAFFDPLGGGDPVLFQHMFWFFG 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 283 HPEVYILVLPAFGIYSEVVATFSRK-TLFGYKSMVYATVAITVLSFVVWVHHFFTMGAGANVNAFFGIMTMIIAIPTGVK 361
Cdd:MTH00048 238 HPEVYVLILPGFGIISHICLSLSNNdDPFGYYGLVFAMFSIVCLGSVVWAHHMFTVGLDVKTAVFFSSVTMIIGVPTGIK 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 362 IFSWLFTMYKGRITYTTPML-WTLGFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHNVIIGGVVFAMFAGIIFYWP 440
Cdd:MTH00048 318 VFSWLYMLLNSRVRKSDPVVwWVVSFIVLFTIGGVTGIVLSASVLDNVLHDTWFVVAHFHYVLSLGSYSSVVIMFIWWWP 397

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 491320759 441 KMFGWRLNETWGKAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYDnPDWDPYVMIAMVGAVMIAIGiACFLMQII 516
Cdd:MTH00048 398 LITGLSLNKYLLQCHCIISMIGFNLCFFPMHYFGLCGLPRRVCVYE-PSYYWINVVCTVGSFISAFS-GCFFVFIL 471
ba3-like_Oxidase_I cd01660
ba3-like heme-copper oxidase subunit I. The ba3 family of heme-copper oxidases are ...
 54-520 3.60e-25

ba3-like heme-copper oxidase subunit I. The ba3 family of heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and some archaea which catalyze the reduction of O2 and simultaneously pump protons across the membrane. It has been proposed that Archaea acquired heme-copper oxidases through gene transfer from Gram-positive bacteria. The ba3 family contains oxidases that lack the conserved residues that form the D- and K-pathways in CcO and ubiquinol oxidase. Instead they contain a potential alternative K-pathway. Additional proton channels have been proposed for this family of oxidases but none have been identified definitively. For general information on the heme-copper oxidase superfamily, please see cd00919.


Pssm-ID: 238830  Cd Length: 473  Bit Score: 109.30  E-value: 3.60e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759  54 KKIGIMYIIVSVVMLLRGfadaIMMRLQQFLARGGGEGYLH-PEHYDQIFTAHGVIMIFFVAMGLVVGLMNISVPLQIGA 132
Cdd:cd01660    3 KKLALAHFVVAFLALLLG----GLFGLLQVLVRTGVFPLPSsGILYYQGLTLHGVLLAIVFTTFFIMGFFYAIVARALLR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 133 RDVAFPLLNsLSFWLFAGAAGLMMVSLALGEfAATGWMAYPPLSGieySPGvgmdYYIwALQISGLGTLLTGVNFFVTII 212
Cdd:cd01660   79 SLFNRRLAW-AGFWLMVIGTVMAAVPILLGQ-ASVLYTFYPPLQA---HPL----FYI-GAALVVVGSWISGFAMFVTLW 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 213 KMRA--PGMKLmdmPIFTWTSLCTAVLIIAAFPVLTATIAMLTLDRYFGFHFFTNdmggsPMLYVNLIWTWGHPEVYILV 290
Cdd:cd01660  149 RWKKanPGKKV---PLATFMVVTTMILWLVASLGVALEVLFQLLPWSLGLVDTVD-----VLLSRTLFWWFGHPLVYFWL 220

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 291 LPAFGIYSEVVATFSRKTLFGYKSMVYATVAITVLSFVVWVHHFFTmgaGANVNAFFGIM----TMIIAIPT-------- 358
Cdd:cd01660  221 LPAYIAWYTILPKIAGGKLFSDPLARLAFILFLLFSTPVGFHHQFA---DPGIGPGWKFIhmvlTFMVALPSlltaftvf 297

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 359 -----------GVKIFSWLFTMYKGRITYTTPMLwtlgFLVTFGIGGLTGVLMAVPPADFLVHNSLFLIAHFHnVIIGGV 427
Cdd:cd01660  298 asleiagrlrgGKGLFGWIRALPWGDPMFLALFL----AMLMFIPGGAGGIINASYQLNYVVHNTAWVPGHFH-LTVGGA 372

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491320759 428 VFAMFAGIIFY-WPKMFGWRLNETW-GKAAFWFWFLGFYFAFMPLYILGFMGMTRRLNTYD------NPDWDPYVMIAMV 499
Cdd:cd01660  373 VALTFMAVAYWlVPHLTGRELAAKRlALAQPWLWFVGMTIMSTAMHVAGLLGAPRRTAEAQygglpaAGEWAPYQQLMAI 452

                        490       500
                 ....*....|....*....|.
gi 491320759 500 GAVMIAIGIACFLMQIIVGFL 520
Cdd:cd01660  453 GGTILFVSGALFLYILFRTLL 473
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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