NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|491222672|ref|WP_005080978|]
View 

hypothetical protein [Mycobacteroides abscessus]

Protein Classification

PQQ-binding-like beta-propeller repeat protein( domain architecture ID 29103)

PQQ (pyrroloquinoline quinone)-binding-like beta-propeller repeat protein

Gene Ontology:  GO:0070968
PubMed:  16232604|11831471

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PQQ_DH_like super family cl11493
PQQ-dependent dehydrogenases and related proteins; This family is composed of dehydrogenases ...
 61-142 2.44e-03

PQQ-dependent dehydrogenases and related proteins; This family is composed of dehydrogenases with pyrroloquinoline quinone (PQQ) as a cofactor, such as ethanol, methanol, and membrane-bound glucose dehydrogenases. The alignment model contains an 8-bladed beta-propeller, and the family also includes distantly related proteins which are not enzymatically active and do not bind PQQ.


The actual alignment was detected with superfamily member TIGR03300:

Pssm-ID: 472205 [Multi-domain]  Cd Length: 377  Bit Score: 39.92  E-value: 2.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491222672   61 RELW--STASAATKGPVIASGAVV--SADGHdVVAHDPATGAQLWSYARR--NLDLCGAIG--FIDDAVAVyrdARGCGQ 132
Cdd:TIGR03300 126 KELWraKLSSEVLSPPLVANGLVVvrTNDGR-LTALDAATGERLWTYSRVtpPLTLRGSASpvIADGGVLV---GFAGGK 201

                          90
                  ....*....|
gi 491222672  133 VTMIDGQTGR 142
Cdd:TIGR03300 202 LVALDLQTGQ 211
 
Name Accession Description Interval E-value
assembly_YfgL TIGR03300
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ...
 61-142 2.44e-03

outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274511 [Multi-domain]  Cd Length: 377  Bit Score: 39.92  E-value: 2.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491222672   61 RELW--STASAATKGPVIASGAVV--SADGHdVVAHDPATGAQLWSYARR--NLDLCGAIG--FIDDAVAVyrdARGCGQ 132
Cdd:TIGR03300 126 KELWraKLSSEVLSPPLVANGLVVvrTNDGR-LTALDAATGERLWTYSRVtpPLTLRGSASpvIADGGVLV---GFAGGK 201

                          90
                  ....*....|
gi 491222672  133 VTMIDGQTGR 142
Cdd:TIGR03300 202 LVALDLQTGQ 211
PQQ COG1520
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ...
 62-105 4.98e-03

Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441129 [Multi-domain]  Cd Length: 370  Bit Score: 38.64  E-value: 4.98e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 491222672  62 ELWST--ASAATKGPVIASGAVV--SADGHdVVAHDPATGAQLWSYAR 105
Cdd:COG1520  119 ELWRArlSSEVLAAPAVAGGRVVvrTGDGR-VYALDAATGERLWSYQR 165
 
Name Accession Description Interval E-value
assembly_YfgL TIGR03300
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ...
 61-142 2.44e-03

outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274511 [Multi-domain]  Cd Length: 377  Bit Score: 39.92  E-value: 2.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491222672   61 RELW--STASAATKGPVIASGAVV--SADGHdVVAHDPATGAQLWSYARR--NLDLCGAIG--FIDDAVAVyrdARGCGQ 132
Cdd:TIGR03300 126 KELWraKLSSEVLSPPLVANGLVVvrTNDGR-LTALDAATGERLWTYSRVtpPLTLRGSASpvIADGGVLV---GFAGGK 201

                          90
                  ....*....|
gi 491222672  133 VTMIDGQTGR 142
Cdd:TIGR03300 202 LVALDLQTGQ 211
PQQ COG1520
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ...
 62-105 4.98e-03

Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441129 [Multi-domain]  Cd Length: 370  Bit Score: 38.64  E-value: 4.98e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 491222672  62 ELWST--ASAATKGPVIASGAVV--SADGHdVVAHDPATGAQLWSYAR 105
Cdd:COG1520  119 ELWRArlSSEVLAAPAVAGGRVVvrTGDGR-VYALDAATGERLWSYQR 165
PQQ COG1520
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ...
 61-123 7.01e-03

Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441129 [Multi-domain]  Cd Length: 370  Bit Score: 38.26  E-value: 7.01e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 491222672  61 RELWSTASAATKGPVIASGAVVSADGHD-VVAHDPATGAQLWS---YARRNLdlcGAIGFIDDAVAV 123
Cdd:COG1520  254 RVLWSRDLSSYTGLAVDGNNLYVTDDDGrVWALDRRNGAELWKqdaLLYRGL---TAPVVLGDYVVV 317
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH