|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15136 |
PRK15136 |
multidrug efflux MFS transporter periplasmic adaptor subunit EmrA; |
1-390 |
0e+00 |
|
multidrug efflux MFS transporter periplasmic adaptor subunit EmrA;
Pssm-ID: 185090 [Multi-domain] Cd Length: 390 Bit Score: 780.03 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 1 MSASAETQNPQQPSGKKKQRKFWLLLLTVIFIVIGVAYLVYWFLVLRHHQETDDAYVSGNQVQIMAQVNGSVNSVNFDNT 80
Cdd:PRK15136 1 MSANAETQTPQQPVKKKGKRKRALLLLTLLFIIIGVAYGIYWFLVLRHHQETDDAYVAGNQVQIMSQVSGSVTKVWADNT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 81 DYVRQGDVLLTLDPTDAEQALERAKTSLANSVRQTHQLIINSKQYQANIALRKSDLSKAENDLKRRVVLGSVDAIGREEL 160
Cdd:PRK15136 81 DFVKEGDVLVTLDPTDAEQAFEKAKTALANSVRQTHQLMINSKQYQANIELQKTALAQAQSDLNRRVPLGNANLIGREEL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 161 QHARDAVDSAKAALEVAVQQYNANQAMVLDTPLEKQPAIQQSAAQMRDAWLALQRTKIISPITGYVSRRSVQVGAQIAAG 240
Cdd:PRK15136 161 QHARDAVASAQAQLDVAIQQYNANQAMILNTPLEDQPAVQQAATEVRNAWLALQRTKIVSPMTGYVSRRSVQVGAQISPT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 241 SPLMAVVPAEHIWVDANFKETQIANMRIGQSATVVSDIYGDDVVYTGKVVGIDMGTGSAFSLLPAQNATGNWIKVVQRLP 320
Cdd:PRK15136 241 TPLMAVVPATNLWVDANFKETQLANMRIGQPATITSDIYGDDVVYTGKVVGLDMGTGSAFSLLPAQNATGNWIKVVQRLP 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 321 VRIELDAKQIADHPLRIGLSTQVKVDTTNLDGRVLSDVVRDKPLYQTNALALNLAPVDQMIADVIHANAG 390
Cdd:PRK15136 321 VRIELDAKQLAQHPLRIGLSTLVTVDTANRDGQVLANQVRSTPAYESNALEIDLAPVNKLIDDIIQANAG 390
|
|
| 8a0101 |
TIGR00998 |
efflux pump membrane protein (multidrug resistance protein A); [Transport and binding proteins, ... |
20-345 |
1.08e-157 |
|
efflux pump membrane protein (multidrug resistance protein A); [Transport and binding proteins, Other]
Pssm-ID: 273385 [Multi-domain] Cd Length: 334 Bit Score: 446.93 E-value: 1.08e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 20 RKFWLLLLTVIFIVIGVAYLVYWFLVLRHHQETDDAYVSGNQVQIMAQVNGSVNSVNFDNTDYVRQGDVLLTLDPTDAEQ 99
Cdd:TIGR00998 1 RKYFLLLLVVLLIVVAGAYAIYWFLVLRDYESTDDAYVKANQLQVSSQVSGSVIEVNVDDTDYVKQGDVLVRLDPTNAEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 100 ALERAKTSLANSVRQTHQLIINSKQYQANIALRKSDLSKA-------ENDLKRRVVLGSVDAIGREELQHARDAVDSAKA 172
Cdd:TIGR00998 81 ALAKAEANLAALVRQTKQLEITVQQLQAKVESLKIKLEQArekllqaELDLRRRVPLFKKGLISREELDHARKALLSAKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 173 ALEVAVQ-QYNANQAMVLDTPLEKQPAIQQSAAQMRDAWLALQRTKIISPITGYVSRRSVQVGAQIAAGSPLMAVVPAEH 251
Cdd:TIGR00998 161 ALNAAIQeQLNANQALVRGTPLKKQPAVQEAKERLKTAWLALKRTVIRAPFDGYVARRFVQVGQVVSPGQPLMAVVPAEQ 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 252 IWVDANFKETQIANMRIGQSATVVSDIYGDDVVYTGKVVGIDMGTGSAFSLLPAQNATGNWIKVVQRLPVRIELDAKQIA 331
Cdd:TIGR00998 241 MYVEANFKETQLKNVRIGQPVTIRSDLYGSDVVFEGKVTGISMGTGSAFSLLPAQNATGNWIKVVQRLPVRIKLDPKELD 320
|
330
....*....|....
gi 491092175 332 DHPLRIGLSTQVKV 345
Cdd:TIGR00998 321 EHPLRIGLSAEVEI 334
|
|
| EmrA |
COG1566 |
Multidrug resistance efflux pump EmrA [Defense mechanisms]; |
26-347 |
1.09e-76 |
|
Multidrug resistance efflux pump EmrA [Defense mechanisms];
Pssm-ID: 441174 [Multi-domain] Cd Length: 331 Bit Score: 240.33 E-value: 1.09e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 26 LLTVIFIVIGVAYLVYWFLVLRHHQE-TDDAYVSGNQVQIMAQVNGSVNSVNFDNTDYVRQGDVLLTLDPTDAEQALERA 104
Cdd:COG1566 9 LLALVLLLLALGLALWAAGRNGPDEPvTADGRVEARVVTVAAKVSGRVTEVLVKEGDRVKKGQVLARLDPTDLQAALAQA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 105 KTSLANSVRQTHQLIINS------KQYQANIALRKSDLSKAENDLKRRVVLGSVDAIGREELQHARDAVDSAKAALEVAV 178
Cdd:COG1566 89 EAQLAAAEAQLARLEAELgaeaeiAAAEAQLAAAQAQLDLAQRELERYQALYKKGAVSQQELDEARAALDAAQAQLEAAQ 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 179 QQYNANQAMV--LDTPLEKQPAIQQSAAQMRDAWLALQRTKIISPITGYVSRRSVQVGAQIAAGSPLMAVVPAEHIWVDA 256
Cdd:COG1566 169 AQLAQAQAGLreEEELAAAQAQVAQAEAALAQAELNLARTTIRAPVDGVVTNLNVEPGEVVSAGQPLLTIVPLDDLWVEA 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 257 NFKETQIANMRIGQSATVVSDIYgDDVVYTGKVVGIDMGTGSAFsllPAQNATGNwikVVQRLPVRIELDAKQiaDHPLR 336
Cdd:COG1566 249 YVPETDLGRVKPGQPVEVRVDAY-PDRVFEGKVTSISPGAGFTS---PPKNATGN---VVQRYPVRIRLDNPD--PEPLR 319
|
330
....*....|.
gi 491092175 337 IGLSTQVKVDT 347
Cdd:COG1566 320 PGMSATVEIDT 330
|
|
| CusB_dom_1 |
pfam00529 |
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ... |
47-347 |
2.88e-58 |
|
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.
Pssm-ID: 425733 [Multi-domain] Cd Length: 322 Bit Score: 192.64 E-value: 2.88e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 47 RHHQETDDAYVSGNQVQIMAQVNGSVNSVNFDNTDYVRQGDVLLTLDPTDAEQALERAKTSLANSVRQTHQLIINSKQYQ 126
Cdd:pfam00529 6 KGVEAPGRVVVSGNAKAVQPQVSGIVTRVLVKEGDRVKAGDVLFQLDPTDYQAALDSAEAQLAKAQAQVARLQAELDRLQ 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 127 ------------------------ANIALRKSDLSKAENDLKRRVVLGSVDAIGREELQHARDAVDSAKAALEVAVQQ-- 180
Cdd:pfam00529 86 aleselaisrqdydgataqlraaqAAVKAAQAQLAQAQIDLARRRVLAPIGGISRESLVTAGALVAQAQANLLATVAQld 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 181 ---------YNANQAMVLDTPLEKQPAIQQSAAQMRDAWLALQRTKIISPITGYVSRRSVQV-GAQIAAGSPLMAVVPAE 250
Cdd:pfam00529 166 qiyvqitqsAAENQAEVRSELSGAQLQIAEAEAELKLAKLDLERTEIRAPVDGTVAFLSVTVdGGTVSAGLRLMFVVPED 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 251 HIWVDANFKETQIANMRIGQSATVVSDIYGDDV--VYTGKVVGIDMGTGsafsllpaqnatgnwikvvqrlPVRIELDAK 328
Cdd:pfam00529 246 NLLVPGMFVETQLDQVRVGQPVLIPFDAFPQTKtgRFTGVVVGISPDTG----------------------PVRVVVDKA 303
|
330
....*....|....*....
gi 491092175 329 QIADHPLRIGLSTQVKVDT 347
Cdd:pfam00529 304 QGPYYPLRIGLSAGALVRL 322
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15136 |
PRK15136 |
multidrug efflux MFS transporter periplasmic adaptor subunit EmrA; |
1-390 |
0e+00 |
|
multidrug efflux MFS transporter periplasmic adaptor subunit EmrA;
Pssm-ID: 185090 [Multi-domain] Cd Length: 390 Bit Score: 780.03 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 1 MSASAETQNPQQPSGKKKQRKFWLLLLTVIFIVIGVAYLVYWFLVLRHHQETDDAYVSGNQVQIMAQVNGSVNSVNFDNT 80
Cdd:PRK15136 1 MSANAETQTPQQPVKKKGKRKRALLLLTLLFIIIGVAYGIYWFLVLRHHQETDDAYVAGNQVQIMSQVSGSVTKVWADNT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 81 DYVRQGDVLLTLDPTDAEQALERAKTSLANSVRQTHQLIINSKQYQANIALRKSDLSKAENDLKRRVVLGSVDAIGREEL 160
Cdd:PRK15136 81 DFVKEGDVLVTLDPTDAEQAFEKAKTALANSVRQTHQLMINSKQYQANIELQKTALAQAQSDLNRRVPLGNANLIGREEL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 161 QHARDAVDSAKAALEVAVQQYNANQAMVLDTPLEKQPAIQQSAAQMRDAWLALQRTKIISPITGYVSRRSVQVGAQIAAG 240
Cdd:PRK15136 161 QHARDAVASAQAQLDVAIQQYNANQAMILNTPLEDQPAVQQAATEVRNAWLALQRTKIVSPMTGYVSRRSVQVGAQISPT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 241 SPLMAVVPAEHIWVDANFKETQIANMRIGQSATVVSDIYGDDVVYTGKVVGIDMGTGSAFSLLPAQNATGNWIKVVQRLP 320
Cdd:PRK15136 241 TPLMAVVPATNLWVDANFKETQLANMRIGQPATITSDIYGDDVVYTGKVVGLDMGTGSAFSLLPAQNATGNWIKVVQRLP 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 321 VRIELDAKQIADHPLRIGLSTQVKVDTTNLDGRVLSDVVRDKPLYQTNALALNLAPVDQMIADVIHANAG 390
Cdd:PRK15136 321 VRIELDAKQLAQHPLRIGLSTLVTVDTANRDGQVLANQVRSTPAYESNALEIDLAPVNKLIDDIIQANAG 390
|
|
| 8a0101 |
TIGR00998 |
efflux pump membrane protein (multidrug resistance protein A); [Transport and binding proteins, ... |
20-345 |
1.08e-157 |
|
efflux pump membrane protein (multidrug resistance protein A); [Transport and binding proteins, Other]
Pssm-ID: 273385 [Multi-domain] Cd Length: 334 Bit Score: 446.93 E-value: 1.08e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 20 RKFWLLLLTVIFIVIGVAYLVYWFLVLRHHQETDDAYVSGNQVQIMAQVNGSVNSVNFDNTDYVRQGDVLLTLDPTDAEQ 99
Cdd:TIGR00998 1 RKYFLLLLVVLLIVVAGAYAIYWFLVLRDYESTDDAYVKANQLQVSSQVSGSVIEVNVDDTDYVKQGDVLVRLDPTNAEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 100 ALERAKTSLANSVRQTHQLIINSKQYQANIALRKSDLSKA-------ENDLKRRVVLGSVDAIGREELQHARDAVDSAKA 172
Cdd:TIGR00998 81 ALAKAEANLAALVRQTKQLEITVQQLQAKVESLKIKLEQArekllqaELDLRRRVPLFKKGLISREELDHARKALLSAKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 173 ALEVAVQ-QYNANQAMVLDTPLEKQPAIQQSAAQMRDAWLALQRTKIISPITGYVSRRSVQVGAQIAAGSPLMAVVPAEH 251
Cdd:TIGR00998 161 ALNAAIQeQLNANQALVRGTPLKKQPAVQEAKERLKTAWLALKRTVIRAPFDGYVARRFVQVGQVVSPGQPLMAVVPAEQ 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 252 IWVDANFKETQIANMRIGQSATVVSDIYGDDVVYTGKVVGIDMGTGSAFSLLPAQNATGNWIKVVQRLPVRIELDAKQIA 331
Cdd:TIGR00998 241 MYVEANFKETQLKNVRIGQPVTIRSDLYGSDVVFEGKVTGISMGTGSAFSLLPAQNATGNWIKVVQRLPVRIKLDPKELD 320
|
330
....*....|....
gi 491092175 332 DHPLRIGLSTQVKV 345
Cdd:TIGR00998 321 EHPLRIGLSAEVEI 334
|
|
| EmrA |
COG1566 |
Multidrug resistance efflux pump EmrA [Defense mechanisms]; |
26-347 |
1.09e-76 |
|
Multidrug resistance efflux pump EmrA [Defense mechanisms];
Pssm-ID: 441174 [Multi-domain] Cd Length: 331 Bit Score: 240.33 E-value: 1.09e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 26 LLTVIFIVIGVAYLVYWFLVLRHHQE-TDDAYVSGNQVQIMAQVNGSVNSVNFDNTDYVRQGDVLLTLDPTDAEQALERA 104
Cdd:COG1566 9 LLALVLLLLALGLALWAAGRNGPDEPvTADGRVEARVVTVAAKVSGRVTEVLVKEGDRVKKGQVLARLDPTDLQAALAQA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 105 KTSLANSVRQTHQLIINS------KQYQANIALRKSDLSKAENDLKRRVVLGSVDAIGREELQHARDAVDSAKAALEVAV 178
Cdd:COG1566 89 EAQLAAAEAQLARLEAELgaeaeiAAAEAQLAAAQAQLDLAQRELERYQALYKKGAVSQQELDEARAALDAAQAQLEAAQ 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 179 QQYNANQAMV--LDTPLEKQPAIQQSAAQMRDAWLALQRTKIISPITGYVSRRSVQVGAQIAAGSPLMAVVPAEHIWVDA 256
Cdd:COG1566 169 AQLAQAQAGLreEEELAAAQAQVAQAEAALAQAELNLARTTIRAPVDGVVTNLNVEPGEVVSAGQPLLTIVPLDDLWVEA 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 257 NFKETQIANMRIGQSATVVSDIYgDDVVYTGKVVGIDMGTGSAFsllPAQNATGNwikVVQRLPVRIELDAKQiaDHPLR 336
Cdd:COG1566 249 YVPETDLGRVKPGQPVEVRVDAY-PDRVFEGKVTSISPGAGFTS---PPKNATGN---VVQRYPVRIRLDNPD--PEPLR 319
|
330
....*....|.
gi 491092175 337 IGLSTQVKVDT 347
Cdd:COG1566 320 PGMSATVEIDT 330
|
|
| CusB_dom_1 |
pfam00529 |
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ... |
47-347 |
2.88e-58 |
|
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.
Pssm-ID: 425733 [Multi-domain] Cd Length: 322 Bit Score: 192.64 E-value: 2.88e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 47 RHHQETDDAYVSGNQVQIMAQVNGSVNSVNFDNTDYVRQGDVLLTLDPTDAEQALERAKTSLANSVRQTHQLIINSKQYQ 126
Cdd:pfam00529 6 KGVEAPGRVVVSGNAKAVQPQVSGIVTRVLVKEGDRVKAGDVLFQLDPTDYQAALDSAEAQLAKAQAQVARLQAELDRLQ 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 127 ------------------------ANIALRKSDLSKAENDLKRRVVLGSVDAIGREELQHARDAVDSAKAALEVAVQQ-- 180
Cdd:pfam00529 86 aleselaisrqdydgataqlraaqAAVKAAQAQLAQAQIDLARRRVLAPIGGISRESLVTAGALVAQAQANLLATVAQld 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 181 ---------YNANQAMVLDTPLEKQPAIQQSAAQMRDAWLALQRTKIISPITGYVSRRSVQV-GAQIAAGSPLMAVVPAE 250
Cdd:pfam00529 166 qiyvqitqsAAENQAEVRSELSGAQLQIAEAEAELKLAKLDLERTEIRAPVDGTVAFLSVTVdGGTVSAGLRLMFVVPED 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 251 HIWVDANFKETQIANMRIGQSATVVSDIYGDDV--VYTGKVVGIDMGTGsafsllpaqnatgnwikvvqrlPVRIELDAK 328
Cdd:pfam00529 246 NLLVPGMFVETQLDQVRVGQPVLIPFDAFPQTKtgRFTGVVVGISPDTG----------------------PVRVVVDKA 303
|
330
....*....|....*....
gi 491092175 329 QIADHPLRIGLSTQVKVDT 347
Cdd:pfam00529 304 QGPYYPLRIGLSAGALVRL 322
|
|
| PRK10476 |
PRK10476 |
multidrug transporter subunit MdtN; |
9-345 |
1.23e-35 |
|
multidrug transporter subunit MdtN;
Pssm-ID: 182488 [Multi-domain] Cd Length: 346 Bit Score: 133.61 E-value: 1.23e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 9 NPQQPSGKKKqrkfwllLLTVIFIVIGVAYLVYWFLVLRHHQETDDAYVSGNQVQIMAQVNGSVNSVNFDNTDYVRQGDV 88
Cdd:PRK10476 3 STPKKSPRKK-------LPALAIVALAIVALVFVIWRTDSAPSTDDAYIDADVVHVASEVGGRIVELAVTENQAVKKGDL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 89 LLTLDPTDAEQALERAKTSLANSVRQ--THQLIINSKQYQANIALR-----KSDLSKAENDLKRRVVLGSVDAIGREELQ 161
Cdd:PRK10476 76 LFRIDPRPYELTVAQAQADLALADAQimTTQRSVDAERSNAASANEqveraRANAKLATRTLERLEPLLAKGYVSAQQVD 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 162 HARDAVDSAKAALEVAVQQYNANQAMVLDTPLEkQPAIQQSAAQMRDAWLALQRTKIISPITGYVSRRSVQVGAQIAAGS 241
Cdd:PRK10476 156 QARTAQRDAEVSLNQALLQAQAAAAAVGGVDAL-VAQRAAREAALAIAELHLEDTTVRAPFDGRVVGLKVSVGEFAAPMQ 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 242 PLMAVVPAEHIWVDANFKETQIANMRIGQSATVVSDIyGDDVVYTGKVVGIDMGTGSAFSL-----LPAQNATGNWIKVV 316
Cdd:PRK10476 235 PIFTLIDTDHWYAIANFRETDLKNIRVGDCATVYSMI-DRGRPFEGKVDSIGWGVLPDDGGnvprgLPYVPRSINWVRVA 313
|
330 340 350
....*....|....*....|....*....|
gi 491092175 317 QRLPVRIELDAkqiADHPL-RIGLSTQVKV 345
Cdd:PRK10476 314 QRFPVRIMLDK---PDPELfRIGASAVVEL 340
|
|
| AcrA |
COG0845 |
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope ... |
60-355 |
7.54e-35 |
|
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope biogenesis, Defense mechanisms];
Pssm-ID: 440606 [Multi-domain] Cd Length: 324 Bit Score: 130.83 E-value: 7.54e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 60 NQVQIMAQVNGSVNSVNFDNTDYVRQGDVLLTLDPTDAEQALERAktslansvrqthqliinskqyQANIALRKSDLSKA 139
Cdd:COG0845 22 REVEVRARVSGRVEEVLVDEGDRVKKGQVLARLDPPDLQAALAQA---------------------QAQLAAAQAQLELA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 140 ENDLKRRVVLGSVDAIGREELQHARDAVDSAKAALEVAvqqynanqamvldtplekqpaiqqsAAQMRDAWLALQRTKII 219
Cdd:COG0845 81 KAELERYKALLKKGAVSQQELDQAKAALDQAQAALAAA-------------------------QAALEQARANLAYTTIR 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 220 SPITGYVSRRSVQVGAQIAAGSPLMAVVPAEHIWVDANFKETQIANMRIGQSATVVSDIYgDDVVYTGKVVGIDmgtgsa 299
Cdd:COG0845 136 APFDGVVGERNVEPGQLVSAGTPLFTIADLDPLEVEFDVPESDLARLKVGQPVTVTLDAG-PGKTFEGKVTFID------ 208
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 491092175 300 fsllPAQNATgnwikvVQRLPVRIELDAkqiADHPLRIGLSTQVKVDTTNLDGRVL 355
Cdd:COG0845 209 ----PAVDPA------TRTVRVRAELPN---PDGLLRPGMFVRVRIVLGERENALL 251
|
|
| RND_mfp |
TIGR01730 |
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion ... |
57-293 |
3.95e-21 |
|
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273776 [Multi-domain] Cd Length: 322 Bit Score: 92.76 E-value: 3.95e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 57 VSGNQVQIMAQVNGSVNSVNFDNTDYVRQGDVLLTLDPTDAEQALERAKtslansvrqthqliinskqyqANIALRKSDL 136
Cdd:TIGR01730 22 EAVDEADLAAEVAGKITKISVREGQKVKKGQVLARLDDDDYQLALQAAL---------------------AQLAAAEAQL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 137 SKAENDLKRRVVLGSVDAIGREELqhardavDSAKAALEVAVQQynanqamvldtplekqpaIQQSAAQMRDAWLALQRT 216
Cdd:TIGR01730 81 ELAQRSFERAERLVKRNAVSQADL-------DDAKAAVEAAQAD------------------LEAAKASLASAQLNLRYT 135
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 491092175 217 KIISPITGYVSRRSVQVGAQIAAGSPLMAVVPAEHIWVDANFKETQIANMRIGQSATVVSDIYgDDVVYTGKVVGID 293
Cdd:TIGR01730 136 EIRAPFDGTIGRRLVEVGAYVTAGQTLATIVDLDPLEADFSVPERDLPQLRRGQTLTVELDAL-PGEEFKGKLRFID 211
|
|
| PRK03598 |
PRK03598 |
putative efflux pump membrane fusion protein; Provisional |
20-289 |
1.27e-19 |
|
putative efflux pump membrane fusion protein; Provisional
Pssm-ID: 235136 [Multi-domain] Cd Length: 331 Bit Score: 88.87 E-value: 1.27e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 20 RKFWLLLLTVIfIVIGVAYLVYWFLvlrhHQETDDAYVSGN----QVQIMAQVNGSVNSVNFDNTDYVRQGDVLLTLDPT 95
Cdd:PRK03598 3 KKVVIGLAVVV-LAAAVAGGWWWYQ----SRQDNGLTLYGNvdirTVNLGFRVGGRLASLAVDEGDAVKAGQVLGELDAA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 96 DAEQALERAKTSLANSVRQTHQLIINSK-----QYQANIALRKSDLSKAENDLKRRVVLGSVDAIGREELQHARDAVDSA 170
Cdd:PRK03598 78 PYENALMQAKANVSVAQAQLDLMLAGYRdeeiaQARAAVKQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 171 KAALEVAVQQYNANQA--MVLDTPlEKQPAIQQSAAQMRDAWLALQRTKIISPITGYVSRRSVQVGAQIAAGSPLMAVVP 248
Cdd:PRK03598 158 QATLKSAQDKLSQYREgnRPQDIA-QAKASLAQAQAALAQAELNLQDTELIAPSDGTILTRAVEPGTMLNAGSTVFTLSL 236
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 491092175 249 AEHIWVDANFKETQIANMRIGQSATVVSDIYGDDvVYTGKV 289
Cdd:PRK03598 237 TRPVWVRAYVDERNLGQAQPGRKVLLYTDGRPDK-PYHGQI 276
|
|
| PRK10559 |
PRK10559 |
p-hydroxybenzoic acid efflux pump subunit AaeA; |
24-329 |
2.64e-17 |
|
p-hydroxybenzoic acid efflux pump subunit AaeA;
Pssm-ID: 182548 [Multi-domain] Cd Length: 310 Bit Score: 81.71 E-value: 2.64e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 24 LLLLTVIFIVIGVAYLVY----WflvlrhhqeTDDAYVSGNQVQIMAQVNGSVNSVNFDNTDYVRQGDVLLTLDPTDAEQ 99
Cdd:PRK10559 15 LVLVILAFIAIFRAWVFYtespW---------TRDARFSADVVAIAPDVSGLITQVNVHDNQLVKKGQVLFTIDQPRYQK 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 100 ALERAKTSLAnsvrqTHQLIINSKQYQANialrksdlskaendlkRRVVLGsVDAIGREElqhardaVDSAKAALEVAVQ 179
Cdd:PRK10559 86 ALAEAEADVA-----YYQVLAQEKRREAG----------------RRNRLG-VQAMSREE-------IDQANNVLQTVLH 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 180 QYNANQAmVLDTplekqpaiqqsaaqmrdAWLALQRTKIISPITGYVSRRSVQVGAQIAAGSPLMAVVPAEHIWVDANFK 259
Cdd:PRK10559 137 QLAKAQA-TRDL-----------------AKLDLERTVIRAPADGWVTNLNVYTGEFITRGSTAVALVKQNSFYVLAYME 198
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 491092175 260 ETQIANMRIGQSATVVSdiYGDDVVYTGKVVGIDMGTGSAFSL-----LPAQNATGNWIKVVQRLPVRIELDAKQ 329
Cdd:PRK10559 199 ETKLEGVRPGYRAEITP--LGSNKVLKGTVDSVAAGVTNSSSTrdskgMATIDSNLEWVRLAQRVPVRIRLDNQQ 271
|
|
| type_I_hlyD |
TIGR01843 |
type I secretion membrane fusion protein, HlyD family; Type I secretion is an ABC transport ... |
57-372 |
8.62e-11 |
|
type I secretion membrane fusion protein, HlyD family; Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 130902 [Multi-domain] Cd Length: 423 Bit Score: 63.10 E-value: 8.62e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 57 VSGNQVQIMAQVNGSVNSVNFDNTDYVRQGDVLLTLDPTDAEQALERAKTSLAN-------------------------- 110
Cdd:TIGR01843 39 PSGNVKVVQHLEGGIVREILVREGDRVKAGQVLVELDATDVEADAAELESQVLRleaevarlraeadsqaaiefpddlls 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 111 ------------------SVRQTHQLIINS-----KQYQANIALRKSDLSKAENDLK---RRVV----LGSVDAIGRE-- 158
Cdd:TIGR01843 119 aedpavpelikgqqslfeSRKSTLRAQLELilaqiKQLEAELAGLQAQLQALRQQLEvisEELEarrkLKEKGLVSRLel 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 159 -ELQHARDA----VDSAKAALEVAVQQYNANQAMVLDTPLEKQPAIQQSAAQMRD-----------AWLALQRTKIISPI 222
Cdd:TIGR01843 199 lELERERAEaqgeLGRLEAELEVLKRQIDELQLERQQIEQTFREEVLEELTEAQArlaelrerlnkARDRLQRLIIRSPV 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 223 TGYVSRRSVQ-VGAQIAAGSPLMAVVPAEH-IWVDANFKETQIANMRIGQSATVVSDIYgDDVVY---TGKVVGIdmgtg 297
Cdd:TIGR01843 279 DGTVQSLKVHtVGGVVQPGETLMEIVPEDDpLEIEAKLSPKDIGFVHVGQPAEIKFSAF-PYRRYgilNGKVKSI----- 352
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 491092175 298 SAfSLLPAQNATGNWikvvqrLPVRIELDAKQIADHPLRIGLS--TQVKVDTTNLDGRVLSDVVrdKPLYQTNALAL 372
Cdd:TIGR01843 353 SP-DTFTDERGGGPY------YRVRISIDQNTLGIGPKGLELSpgMPVTADIKTGERTVIEYLL--KPITDSVQEAL 420
|
|
| HlyD_3 |
pfam13437 |
HlyD family secretion protein; This is a family of largely bacterial haemolysin translocator ... |
217-338 |
5.19e-09 |
|
HlyD family secretion protein; This is a family of largely bacterial haemolysin translocator HlyD proteins.
Pssm-ID: 433206 [Multi-domain] Cd Length: 104 Bit Score: 53.52 E-value: 5.19e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 217 KIISPITGYVSRRSVQVGAQIAAGSPLMAVVPAEHIWVDANFKETQIANMRIGQSATVVSDiYGDDVVYTGKVVGIDmgt 296
Cdd:pfam13437 1 TIRAPVDGVVAELNVEEGQVVQAGDPLATIVPPDRLLVEAFVPAADLGSLKKGQKVTLKLD-PGSDYTLEGKVVRIS--- 76
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 491092175 297 gsafsllPAQNATGnwikvvQRLPVRIELDAKQIADhPLRIG 338
Cdd:pfam13437 77 -------PTVDPDT------GVIPVRVSIENPKTPI-PLLPG 104
|
|
| HlyD_D23 |
pfam16576 |
Barrel-sandwich domain of CusB or HlyD membrane-fusion; HlyD_D23 is the combined domains 2 and ... |
214-293 |
6.39e-09 |
|
Barrel-sandwich domain of CusB or HlyD membrane-fusion; HlyD_D23 is the combined domains 2 and 3 of the membrane-fusion proteins CusB and HlyD, which forms a barrel-sandwich. CusB and HlyD proteins are membrane fusion proteins of the CusCFBA copper efflux system in E.coli and related bacteria. The whole molecule hinges between D2 and D3. Efflux systems of this resistance-nodulation-division group - RND - have been developed to excrete poisonous metal ions, and in E.coli the only one that deals with silver and copper is the CusA transporter. The transporter CusA works in conjunction with a periplasmic component that is a membrane fusion protein, eg CusB, and an outer-membrane channel component CusC in a CusABC complex driven by import of protons.
Pssm-ID: 435440 [Multi-domain] Cd Length: 214 Bit Score: 55.59 E-value: 6.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 214 QRTKIISPITGYVSRRSVQVGAQIAAGSPLMAVVPAEHIWVDANFKETQIANMRIGQSATVVSDIYGDDvVYTGKVVGID 293
Cdd:pfam16576 107 PTVTVYAPISGVVTELNVREGMYVQPGDTLFTIADLSTVWVEADVPEQDLALVKVGQPAEVTLPALPGK-TFEGKVDYIY 185
|
|
| PRK09859 |
PRK09859 |
multidrug transporter subunit MdtE; |
63-255 |
9.65e-09 |
|
multidrug transporter subunit MdtE;
Pssm-ID: 137559 [Multi-domain] Cd Length: 385 Bit Score: 56.65 E-value: 9.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 63 QIMAQVNGSVNSVNFDNTDYVRQGDVLLTLDPTDAEQALERAKTSLANSvrqthqliinskqyqanialrKSDLSKAEND 142
Cdd:PRK09859 63 EIRPQVGGIIIKRNFIEGDKVNQGDSLYQIDPAPLQAELNSAKGSLAKA---------------------LSTASNARIT 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 143 LKRRVVLGSVDAIGREELQHARDAVDSAKAALEVAvqqynanqamvldtplekQPAIQQSAaqmrdawLALQRTKIISPI 222
Cdd:PRK09859 122 FNRQASLLKTNYVSRQDYDTARTQLNEAEANVTVA------------------KAAVEQAT-------INLQYANVTSPI 176
|
170 180 190
....*....|....*....|....*....|....*
gi 491092175 223 TGYVSRRSVQVGAQIAA--GSPLMAVVPAEHIWVD 255
Cdd:PRK09859 177 TGVSGKSSVTVGALVTAnqADSLVTVQRLDPIYVD 211
|
|
| PRK11556 |
PRK11556 |
MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit; |
17-264 |
2.22e-07 |
|
MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit;
Pssm-ID: 183194 [Multi-domain] Cd Length: 415 Bit Score: 52.48 E-value: 2.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 17 KKQRKFWLLLLTVIFIVIGVAYLvYWflvlRHHQETDDA---------------------------------------YV 57
Cdd:PRK11556 2 KGSRKSRWVIVIVVVIAAIAAFW-FW----QGRSTSSSAapgaakqaqqspaggrrgmrsgplapvqaatateqavprYL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 58 SG-------NQVQIMAQVNGSVNSVNFDNTDYVRQGDVLLTLDPTDAEQALERAKTSLANSvrqthqliinskqyqania 130
Cdd:PRK11556 77 TGlgtvtaaNTVTVRSRVDGQLMALHFQEGQQVKAGDLLAEIDPRPFKVALAQAQGQLAKD------------------- 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 131 lrKSDLSKAENDLKRRVVLGSVDAIGREELqhardavdsakaalevavqqyNANQAMVLDTplekQPAIQQSAAQMRDAW 210
Cdd:PRK11556 138 --QATLANARRDLARYQQLAKTNLVSRQEL---------------------DAQQALVSET----EGTIKADEASVASAQ 190
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 491092175 211 LALQRTKIISPITGYVSRRSVQVGAQIAAGSPLMAVVPAEHIWVDANFK--ETQIA 264
Cdd:PRK11556 191 LQLDYSRITAPISGRVGLKQVDVGNQISSGDTTGIVVITQTHPIDLVFTlpESDIA 246
|
|
| PRK11578 |
PRK11578 |
macrolide transporter subunit MacA; Provisional |
16-277 |
1.11e-05 |
|
macrolide transporter subunit MacA; Provisional
Pssm-ID: 183211 [Multi-domain] Cd Length: 370 Bit Score: 47.08 E-value: 1.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 16 KKKQRKFWLLLLTVIFIVIGVAYLV-------YWFLVLRHHQETDDAYVSGN-----QVQIMAQVNGSVNSVNFDNTDYV 83
Cdd:PRK11578 4 RKKVKKRYLIALVIVLAGGITLWRIlnapvptYQTLIVRPGDLQQSVLATGKldalrKVDVGAQVSGQLKTLSVAIGDKV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 84 RQGDVLLTLDPTDAEQALERAKTSLansvrqthqliinsKQYQANIALRKSDLSKAENDLKRRVVLGSVDAIGREELQHA 163
Cdd:PRK11578 84 KKDQLLGVIDPEQAENQIKEVEATL--------------MELRAQRQQAEAELKLARVTLSRQQRLAKTQAVSQQDLDTA 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 164 RDAVDSAKAALEVAVQQYNANQAMvLDTplekqpaiqqsaaqmrdAWLALQRTKIISPITGYVSR-RSVQVGAQIAA--G 240
Cdd:PRK11578 150 ATELAVKQAQIGTIDAQIKRNQAS-LDT-----------------AKTNLDYTRIVAPMAGEVTQiTTLQGQTVIAAqqA 211
|
250 260 270
....*....|....*....|....*....|....*....
gi 491092175 241 SPLMAVVPAEHIWVDANFKETQIANMRIGQSA--TVVSD 277
Cdd:PRK11578 212 PNILTLADMSTMLVKAQVSEADVIHLKPGQKAwfTVLGD 250
|
|
| Biotin_lipoyl_2 |
pfam13533 |
Biotin-lipoyl like; |
60-109 |
3.28e-05 |
|
Biotin-lipoyl like;
Pssm-ID: 433286 Cd Length: 50 Bit Score: 40.89 E-value: 3.28e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 491092175 60 NQVQIMAQVNGSVNSVNFDNTDYVRQGDVLLTLDPTDAEQALERAKTSLA 109
Cdd:pfam13533 1 PVVKIASPVSGKVVAVNVKEGQQVKKGDVLATLDSPELQLQLQQAEAQLA 50
|
|
| YukC |
pfam10140 |
WXG100 protein secretion system (Wss), protein YukC; Members of this family of proteins ... |
16-141 |
1.81e-03 |
|
WXG100 protein secretion system (Wss), protein YukC; Members of this family of proteins include predicted membrane proteins homologous to YukC in B. subtilis. The YukC protein family would participate to the formation of a translocon required for the secretion of WXG100 proteins (pfam06013) in monoderm bacteria, the WXG100 protein secretion system (Wss). This family includes EssB in Staphylococcus aureus.
Pssm-ID: 431082 Cd Length: 357 Bit Score: 39.94 E-value: 1.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491092175 16 KKKQRKF-WLLLLTVIFIVIGVAYLVYWFLVLRHHQEtddAYVSGNQvqimaqvngsvnsvNFDNTDYVrqgDVLLTLDP 94
Cdd:pfam10140 187 KKKWKIQkYIGIGLIVLLIPLLIYLIYLLFFVQPKQE---AIIAANR--------------AFLKKDYS---QVIDTLEK 246
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 491092175 95 TDAEQALERAKTSLANSVRQTHQL-------IINSKQYQAN-------IALRKSDLSKAEN 141
Cdd:pfam10140 247 YDPEKMPKVVKYELAYSYVQTENLsddqkenILNNLTLQSDedyllywIYIGRGEFEEALD 307
|
|
| DUF6341 |
pfam19868 |
Family of unknown function (DUF6341); This family of uncharacterized proteins is found in ... |
23-54 |
2.73e-03 |
|
Family of unknown function (DUF6341); This family of uncharacterized proteins is found in bacteria. Proteins in this family are approximately 70 amino acids in length. There are two conserved sequence motifs, WIF and YW. Probably, they are Uracil phosphoribosyltransferases.
Pssm-ID: 466215 Cd Length: 50 Bit Score: 35.62 E-value: 2.73e-03
10 20 30
....*....|....*....|....*....|....
gi 491092175 23 WLL--LLTVIFIVIGVAYLVYWFLVLRHHQETDD 54
Cdd:pfam19868 8 WWLanIINWIFIIIGFVAFVYWMKQLKKFNDNNE 41
|
|
| |
