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Conserved domains on  [gi|491046807|ref|WP_004908461|]
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MULTISPECIES: hydrogenase maturation factor HybG [Providencia]

Protein Classification

HypC/HybG/HupF family hydrogenase formation chaperone( domain architecture ID 10013514)

HypC/HybG/HupF family hydrogenase formation chaperone such as Escherichia coli hydrogenase maturation factor HybG

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10413 PRK10413
hydrogenase maturation factor HybG;
1-85 1.46e-46

hydrogenase maturation factor HybG;


:

Pssm-ID: 182438  Cd Length: 82  Bit Score: 143.73  E-value: 1.46e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491046807  1 MCLGIPGKIVAVGEDIHQLAQVDVCGVKRDVNIGLICEGETTDLLGQWVLVHVGFAMSIINEEEAQSTLDALtamSQLDH 80
Cdd:PRK10413  1 MCIGVPGQVLAVGEDIHQLAQVEVCGIKRDVNIALICEGNPADLLGQWVLVHVGFAMSIIDEDEAKATLDAL---RQMEY 77


                ....*
gi 491046807 81 EVGDF 85
Cdd:PRK10413 78 DITSA 82
 
Name Accession Description Interval E-value
PRK10413 PRK10413
hydrogenase maturation factor HybG;
1-85 1.46e-46

hydrogenase maturation factor HybG;


Pssm-ID: 182438  Cd Length: 82  Bit Score: 143.73  E-value: 1.46e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491046807  1 MCLGIPGKIVAVGEDIHQLAQVDVCGVKRDVNIGLICEGETTDLLGQWVLVHVGFAMSIINEEEAQSTLDALtamSQLDH 80
Cdd:PRK10413  1 MCIGVPGQVLAVGEDIHQLAQVEVCGIKRDVNIALICEGNPADLLGQWVLVHVGFAMSIIDEDEAKATLDAL---RQMEY 77


                ....*
gi 491046807 81 EVGDF 85
Cdd:PRK10413 78 DITSA 82
HypC COG0298
Hydrogenase maturation factor HybG, HypC/HupF family [Posttranslational modification, protein ...
 1-84 1.67e-30

Hydrogenase maturation factor HybG, HypC/HupF family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440067  Cd Length: 78  Bit Score: 102.91  E-value: 1.67e-30
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491046807  1 MCLGIPGKIVAVGEDihQLAQVDVCGVKRDVNIGLICEgettDLLGQWVLVHVGFAMSIINEEEAQSTLDALTAMSQLDH 80
Cdd:COG0298   1 MCLAIPGKVVEILDG--DTALVDVGGVRREVSLALVPE----VKVGDYVLVHVGFAIEKIDEEEAEETLELLEELGAALE 74


                ....
gi 491046807 81 EVGD 84
Cdd:COG0298  75 EVDA 78
hypC_hupF TIGR00074
hydrogenase assembly chaperone HypC/HupF; This protein is suggested by act as a chaperone for ...
 1-83 5.54e-26

hydrogenase assembly chaperone HypC/HupF; This protein is suggested by act as a chaperone for a hydrogenase large subunit, holding the precursor form before metallocenter nickel incorporation. [SS 12/31/03] More recently proposed additional function is to shuttle the iron atom that has been liganded at the HypC/HypD complex to the precursor of the large hydrogenase (HycE) subunit. . Added metallochaperone and protein mod GO terms. [Protein fate, Protein folding and stabilization, Protein fate, Protein modification and repair]


Pssm-ID: 129184  Cd Length: 76  Bit Score: 91.66  E-value: 5.54e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491046807   1 MCLGIPGKIVAVGEDIhqlAQVDVCGVKRDVNIGLICEgettDLLGQWVLVHVGFAMSIINEEEAQSTLDALTAMSQLDH 80
Cdd:TIGR00074  1 MCIAIPGQVVEIDENI---ALVEFCGIKRDVSLDLVGE----VKVGDYVLVHVGFAISVLDEEEARETLDALQELFDAVE 73


                 ...
gi 491046807  81 EVG 83
Cdd:TIGR00074 74 EGD 76
HupF_HypC pfam01455
HupF/HypC family;
2-72 8.53e-25

HupF/HypC family;


Pssm-ID: 460218  Cd Length: 64  Bit Score: 88.19  E-value: 8.53e-25
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 491046807   2 CLGIPGKIVAVGEDIhqlAQVDVCGVKRDVNIGLICEGEttdlLGQWVLVHVGFAMSIINEEEAQSTLDAL 72
Cdd:pfam01455  1 CLAIPGKVVEIDDEM---AVVDFGGVRREVSLALVPEVK----VGDYVLVHAGFAIEKIDEEEAEETLALL 64
 
Name Accession Description Interval E-value
PRK10413 PRK10413
hydrogenase maturation factor HybG;
1-85 1.46e-46

hydrogenase maturation factor HybG;


Pssm-ID: 182438  Cd Length: 82  Bit Score: 143.73  E-value: 1.46e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491046807  1 MCLGIPGKIVAVGEDIHQLAQVDVCGVKRDVNIGLICEGETTDLLGQWVLVHVGFAMSIINEEEAQSTLDALtamSQLDH 80
Cdd:PRK10413  1 MCIGVPGQVLAVGEDIHQLAQVEVCGIKRDVNIALICEGNPADLLGQWVLVHVGFAMSIIDEDEAKATLDAL---RQMEY 77


                ....*
gi 491046807 81 EVGDF 85
Cdd:PRK10413 78 DITSA 82
HypC COG0298
Hydrogenase maturation factor HybG, HypC/HupF family [Posttranslational modification, protein ...
 1-84 1.67e-30

Hydrogenase maturation factor HybG, HypC/HupF family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440067  Cd Length: 78  Bit Score: 102.91  E-value: 1.67e-30
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491046807  1 MCLGIPGKIVAVGEDihQLAQVDVCGVKRDVNIGLICEgettDLLGQWVLVHVGFAMSIINEEEAQSTLDALTAMSQLDH 80
Cdd:COG0298   1 MCLAIPGKVVEILDG--DTALVDVGGVRREVSLALVPE----VKVGDYVLVHVGFAIEKIDEEEAEETLELLEELGAALE 74


                ....
gi 491046807 81 EVGD 84
Cdd:COG0298  75 EVDA 78
hypC_hupF TIGR00074
hydrogenase assembly chaperone HypC/HupF; This protein is suggested by act as a chaperone for ...
 1-83 5.54e-26

hydrogenase assembly chaperone HypC/HupF; This protein is suggested by act as a chaperone for a hydrogenase large subunit, holding the precursor form before metallocenter nickel incorporation. [SS 12/31/03] More recently proposed additional function is to shuttle the iron atom that has been liganded at the HypC/HypD complex to the precursor of the large hydrogenase (HycE) subunit. . Added metallochaperone and protein mod GO terms. [Protein fate, Protein folding and stabilization, Protein fate, Protein modification and repair]


Pssm-ID: 129184  Cd Length: 76  Bit Score: 91.66  E-value: 5.54e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491046807   1 MCLGIPGKIVAVGEDIhqlAQVDVCGVKRDVNIGLICEgettDLLGQWVLVHVGFAMSIINEEEAQSTLDALTAMSQLDH 80
Cdd:TIGR00074  1 MCIAIPGQVVEIDENI---ALVEFCGIKRDVSLDLVGE----VKVGDYVLVHVGFAISVLDEEEARETLDALQELFDAVE 73


                 ...
gi 491046807  81 EVG 83
Cdd:TIGR00074 74 EGD 76
HupF_HypC pfam01455
HupF/HypC family;
2-72 8.53e-25

HupF/HypC family;


Pssm-ID: 460218  Cd Length: 64  Bit Score: 88.19  E-value: 8.53e-25
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 491046807   2 CLGIPGKIVAVGEDIhqlAQVDVCGVKRDVNIGLICEGEttdlLGQWVLVHVGFAMSIINEEEAQSTLDAL 72
Cdd:pfam01455  1 CLAIPGKVVEIDDEM---AVVDFGGVRREVSLALVPEVK----VGDYVLVHAGFAIEKIDEEEAEETLALL 64
PRK10409 PRK10409
HypC/HybG/HupF family hydrogenase formation chaperone;
1-83 5.65e-23

HypC/HybG/HupF family hydrogenase formation chaperone;


Pssm-ID: 182435  Cd Length: 90  Bit Score: 84.47  E-value: 5.65e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491046807  1 MCLGIPGKIVAVGEDihqLAQVDVCGVKRDVNIGLI--CEGETTDLLGQWVLVHVGFAMSIINEEEAQSTLDALTAMSQL 78
Cdd:PRK10409  1 MCIGVPGQIRTIDGN---QAKVDVCGIQRDVDLTLVgsCDENGQPRVGQWVLVHVGFAMSVINEAEARDTLDALQNMFDV 77


                ....*
gi 491046807 79 DHEVG 83
Cdd:PRK10409 78 EPDVG 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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