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Conserved domains on  [gi|490779081|ref|WP_004641267|]
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MULTISPECIES: type IV pilin protein [Acinetobacter]

Protein Classification

type IV pilin protein( domain architecture ID 11471939)

type IV pilin protein similar to Pseudomonas aeruginosa type IV pilus (T4P) non-core minor pilin PilE, an ssential component of the T4P that plays a role in surface and host cell adhesion, colonization, biofilm maturation, virulence, twitching, adhesion, and retraction of T4P fibers

Gene Ontology:  GO:0043683|GO:0016020
PubMed:  7854130|20338182

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PilE COG4968
Type IV pilus assembly protein PilE [Cell motility, Extracellular structures];
1-112 7.91e-11

Type IV pilus assembly protein PilE [Cell motility, Extracellular structures];


:

Pssm-ID: 443994 [Multi-domain]  Cd Length: 124  Bit Score: 56.24  E-value: 7.91e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490779081   1 MQNNRLTSAQGFTLVELMIVVVIVAIFAAIAIPSYQEYVRRAIAAQAQQEMQRISTELERSKARNFNYLGFPSTVVLPVG 80
Cdd:COG4968    1 MKKRMRRRQRGFTLIELMIVVAIIGILAAIAIPSYQDYVERARRAEAKAALLELAQAQERYYADNGSYPSALADLGLPAS 80

                         90       100       110
                 ....*....|....*....|....*....|..
gi 490779081  81 ATGAaiqYTITVSDGADvSRSLTdsaATGQSW 112
Cdd:COG4968   81 TSGY---YTISIAAAAT-TYTLT---ATPQAD 105
 
Name Accession Description Interval E-value
PilE COG4968
Type IV pilus assembly protein PilE [Cell motility, Extracellular structures];
1-112 7.91e-11

Type IV pilus assembly protein PilE [Cell motility, Extracellular structures];


Pssm-ID: 443994 [Multi-domain]  Cd Length: 124  Bit Score: 56.24  E-value: 7.91e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490779081   1 MQNNRLTSAQGFTLVELMIVVVIVAIFAAIAIPSYQEYVRRAIAAQAQQEMQRISTELERSKARNFNYLGFPSTVVLPVG 80
Cdd:COG4968    1 MKKRMRRRQRGFTLIELMIVVAIIGILAAIAIPSYQDYVERARRAEAKAALLELAQAQERYYADNGSYPSALADLGLPAS 80

                         90       100       110
                 ....*....|....*....|....*....|..
gi 490779081  81 ATGAaiqYTITVSDGADvSRSLTdsaATGQSW 112
Cdd:COG4968   81 TSGY---YTISIAAAAT-TYTLT---ATPQAD 105
ComP_DUS pfam16732
Type IV minor pilin ComP, DNA uptake sequence receptor; ComP-DUS is the DNA-uptake sequence ...
 38-111 4.55e-04

Type IV minor pilin ComP, DNA uptake sequence receptor; ComP-DUS is the DNA-uptake sequence receptor of pathogenic Proteobacteria. ComP is a type IV minor pilin -site on the minor type IV pilin, C one of three minor (low abundance) pilins in pathogenic Proteobacteria Neisseria species (with PilV and PilX). These modulate Tfp-mediated properties without affecting Tfp biogenesis. ComP plays a prominent role in competence at the level of DNA uptake. Comp is exposed on the surface of Neisseria filaments, and it is this that recognizes homotypic DNA through genus-specific DNA uptake sequence (DUS) motifs.


Pssm-ID: 435546  Cd Length: 83  Bit Score: 37.29  E-value: 4.55e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490779081   38 YVRRAIAAQAQQEMQRISTELERSKARNFNYLGFPSTVVLPVGATGAAIQYTITVSDGADVSRSLTDSAATGQS 111
Cdd:pfam16732   1 YVLKSRRADAKAALLEAAQAQERYYTQNGTYADLTALGDLASSPTSGNGYYTISLSAATATTYTLTATPTGGQA 74
 
Name Accession Description Interval E-value
PilE COG4968
Type IV pilus assembly protein PilE [Cell motility, Extracellular structures];
1-112 7.91e-11

Type IV pilus assembly protein PilE [Cell motility, Extracellular structures];


Pssm-ID: 443994 [Multi-domain]  Cd Length: 124  Bit Score: 56.24  E-value: 7.91e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490779081   1 MQNNRLTSAQGFTLVELMIVVVIVAIFAAIAIPSYQEYVRRAIAAQAQQEMQRISTELERSKARNFNYLGFPSTVVLPVG 80
Cdd:COG4968    1 MKKRMRRRQRGFTLIELMIVVAIIGILAAIAIPSYQDYVERARRAEAKAALLELAQAQERYYADNGSYPSALADLGLPAS 80

                         90       100       110
                 ....*....|....*....|....*....|..
gi 490779081  81 ATGAaiqYTITVSDGADvSRSLTdsaATGQSW 112
Cdd:COG4968   81 TSGY---YTISIAAAAT-TYTLT---ATPQAD 105
ComP_DUS pfam16732
Type IV minor pilin ComP, DNA uptake sequence receptor; ComP-DUS is the DNA-uptake sequence ...
 38-111 4.55e-04

Type IV minor pilin ComP, DNA uptake sequence receptor; ComP-DUS is the DNA-uptake sequence receptor of pathogenic Proteobacteria. ComP is a type IV minor pilin -site on the minor type IV pilin, C one of three minor (low abundance) pilins in pathogenic Proteobacteria Neisseria species (with PilV and PilX). These modulate Tfp-mediated properties without affecting Tfp biogenesis. ComP plays a prominent role in competence at the level of DNA uptake. Comp is exposed on the surface of Neisseria filaments, and it is this that recognizes homotypic DNA through genus-specific DNA uptake sequence (DUS) motifs.


Pssm-ID: 435546  Cd Length: 83  Bit Score: 37.29  E-value: 4.55e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490779081   38 YVRRAIAAQAQQEMQRISTELERSKARNFNYLGFPSTVVLPVGATGAAIQYTITVSDGADVSRSLTDSAATGQS 111
Cdd:pfam16732   1 YVLKSRRADAKAALLEAAQAQERYYTQNGTYADLTALGDLASSPTSGNGYYTISLSAATATTYTLTATPTGGQA 74
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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