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Conserved domains on  [gi|490569170|ref|WP_004434190|]
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MULTISPECIES: ABC transporter permease [Sinorhizobium]

Protein Classification

ABC transporter permease( domain architecture ID 11427312)

ABC transporter permease similar to ABC oligopeptide transporter permease proteins (OppB, AppB, and AmiC), the transmembrane subunits (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Gene Ontology:  GO:0055085
PubMed:  18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-321 5.60e-115

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 334.73  E-value: 5.60e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170   1 MLVFIIKRLANAVMVMLAVALLAFLIFRLA-GDPVEMMANEQMTQTDRDNLRERLGLNDGLMTQYTRFVVNAAQGNFGIS 79
Cdd:COG0601    1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLpGDPAAALLGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170  80 YRNGQDVLSLIAERFPATLELVLVATLISLLLGLPLGVLTAIKRGKWYTEGLQFISIVGVSLPSFVVGILLILVFSVTFG 159
Cdd:COG0601   81 FVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 160 WLPAFGRGDVVQLGWwstglltpSGRAAILLPSVALSLYQVTLVMRLVRAEMLEVLRSDYVKFARARGIPRWRIYFRHAL 239
Cdd:COG0601  161 WLPVSGRVSPWEDFL--------DALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHAL 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 240 RNCLMPVVTMTAMNVGSLIAFALITETVFQWPGMGMLFIQAVTFLDIPVMAAYLCIISFIFVVLNTLVDIAYAVIDPRLR 319
Cdd:COG0601  233 RNALIPVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIR 312


                 ..
gi 490569170 320 TA 321
Cdd:COG0601  313 LG 314
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-321 5.60e-115

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 334.73  E-value: 5.60e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170   1 MLVFIIKRLANAVMVMLAVALLAFLIFRLA-GDPVEMMANEQMTQTDRDNLRERLGLNDGLMTQYTRFVVNAAQGNFGIS 79
Cdd:COG0601    1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLpGDPAAALLGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170  80 YRNGQDVLSLIAERFPATLELVLVATLISLLLGLPLGVLTAIKRGKWYTEGLQFISIVGVSLPSFVVGILLILVFSVTFG 159
Cdd:COG0601   81 FVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 160 WLPAFGRGDVVQLGWwstglltpSGRAAILLPSVALSLYQVTLVMRLVRAEMLEVLRSDYVKFARARGIPRWRIYFRHAL 239
Cdd:COG0601  161 WLPVSGRVSPWEDFL--------DALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHAL 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 240 RNCLMPVVTMTAMNVGSLIAFALITETVFQWPGMGMLFIQAVTFLDIPVMAAYLCIISFIFVVLNTLVDIAYAVIDPRLR 319
Cdd:COG0601  233 RNALIPVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIR 312


                 ..
gi 490569170 320 TA 321
Cdd:COG0601  313 LG 314
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 1-322 1.68e-64

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 206.09  E-value: 1.68e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170   1 MLVFIIKRLANAVMVMLAVALLAFLIFRLA-GDP-VEMMANEQMTQTDR--DNLRERLGLNDGLMTQYTRFVVNAAQGNF 76
Cdd:PRK10352   1 MLRYILRRLLLLIPMLLAASVIIFLMLRLGtGDPaLDYLRLSNLPPTPEmlASTRTMLGLDQPLYVQYGTWLWKALHLDF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170  77 GISYRNGQDVLSLIAERFPATLELVLVATLISLLLGLPLGVLTAIKRGKWYTEGLQFISIVGVSLPSFVVGILLILVFSV 156
Cdd:PRK10352  81 GISFATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 157 TFGWLPAFGRGdvvqlgwwstglltpsGRAAILLPSVALSLYQVTLVMRLVRAEMLEVLRSDYVKFARARGIPRWRIYFR 236
Cdd:PRK10352 161 YLQWLPAMGYG----------------GWQHIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERR 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 237 HALRNCLMPVVTMTAMNVGSLIAFALITETVFQWPGMGMLFIQAVTFLDIPVMAAYLCIISFIFVVLNTLVDIAYAVIDP 316
Cdd:PRK10352 225 HILRNASLPMITAVGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDP 304


                 ....*.
gi 490569170 317 RLRTAR 322
Cdd:PRK10352 305 RIRRHE 310
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 119-319 8.20e-23

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 93.13  E-value: 8.20e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170  119 TAIKRGKWYTEGLQFISIVGVSLPSFVVGILLILVFsvtfgWLPAFGRGdvvqlgwwstglltpsgraaiLLPSVALSLY 198
Cdd:pfam00528   8 AALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIA-----ILSILGHG---------------------ILPAIILALL 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170  199 QVTLVMRLVRAEMLEVLRSDYVKFARARGIPRWRIYFRHALRNCLMPVVTMTAMNVGSLIAFALITETVFQWPGMGMLFI 278
Cdd:pfam00528  62 GWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLI 141

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 490569170  279 QAVTFLDIPVMAAYLCIISFIFVVLNTLVDIAYAVIDPRLR 319
Cdd:pfam00528 142 EAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 94-302 2.28e-11

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 61.91  E-value: 2.28e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170  94 FPATLELVLVATLISLLLGLPLGVLTAIKRGKWYTeGLQFISIVGVSLPSFVVGILLILVFSVTFGWLPAFGrgdvvqlg 173
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDR-LLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPG-------- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 174 wwstglltpsgraaILLPSVALSLYQVTLVMRLVRAEMLEVLRSDYVKFARARGIPRWRIYFRHALRNCLMPVVTMTAMN 253
Cdd:cd06261   72 --------------LGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLA 137

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 490569170 254 VGSLIAFALITETVF----QWPGMGMLFIQAVTFLDIPVMAAYLCIISFIFVV 302
Cdd:cd06261  138 FARALGEFALVSFLGggeaPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-321 5.60e-115

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 334.73  E-value: 5.60e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170   1 MLVFIIKRLANAVMVMLAVALLAFLIFRLA-GDPVEMMANEQMTQTDRDNLRERLGLNDGLMTQYTRFVVNAAQGNFGIS 79
Cdd:COG0601    1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLpGDPAAALLGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170  80 YRNGQDVLSLIAERFPATLELVLVATLISLLLGLPLGVLTAIKRGKWYTEGLQFISIVGVSLPSFVVGILLILVFSVTFG 159
Cdd:COG0601   81 FVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 160 WLPAFGRGDVVQLGWwstglltpSGRAAILLPSVALSLYQVTLVMRLVRAEMLEVLRSDYVKFARARGIPRWRIYFRHAL 239
Cdd:COG0601  161 WLPVSGRVSPWEDFL--------DALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHAL 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 240 RNCLMPVVTMTAMNVGSLIAFALITETVFQWPGMGMLFIQAVTFLDIPVMAAYLCIISFIFVVLNTLVDIAYAVIDPRLR 319
Cdd:COG0601  233 RNALIPVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIR 312


                 ..
gi 490569170 320 TA 321
Cdd:COG0601  313 LG 314
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 1-322 1.68e-64

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 206.09  E-value: 1.68e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170   1 MLVFIIKRLANAVMVMLAVALLAFLIFRLA-GDP-VEMMANEQMTQTDR--DNLRERLGLNDGLMTQYTRFVVNAAQGNF 76
Cdd:PRK10352   1 MLRYILRRLLLLIPMLLAASVIIFLMLRLGtGDPaLDYLRLSNLPPTPEmlASTRTMLGLDQPLYVQYGTWLWKALHLDF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170  77 GISYRNGQDVLSLIAERFPATLELVLVATLISLLLGLPLGVLTAIKRGKWYTEGLQFISIVGVSLPSFVVGILLILVFSV 156
Cdd:PRK10352  81 GISFATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 157 TFGWLPAFGRGdvvqlgwwstglltpsGRAAILLPSVALSLYQVTLVMRLVRAEMLEVLRSDYVKFARARGIPRWRIYFR 236
Cdd:PRK10352 161 YLQWLPAMGYG----------------GWQHIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERR 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 237 HALRNCLMPVVTMTAMNVGSLIAFALITETVFQWPGMGMLFIQAVTFLDIPVMAAYLCIISFIFVVLNTLVDIAYAVIDP 316
Cdd:PRK10352 225 HILRNASLPMITAVGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDP 304


                 ....*.
gi 490569170 317 RLRTAR 322
Cdd:PRK10352 305 RIRRHE 310
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 1-319 4.89e-59

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 191.85  E-value: 4.89e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170   1 MLVFIIKRLANAVMVMLAVALLAFL-IFRLAGDPVEMMANEQMTQTDRDNLRERLGLNDGLMTQYTRFVVNAAQGNFGIS 79
Cdd:PRK15081   1 MLNYVIKRLLGLIPTLLIVAVLVFLfVHLLPGDPARLAAGPEADAQVVALVRQQLGLDQPLPHQFWHYISNALQGDFGTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170  80 YRNGQDVLSLIAERFPATLELVLVATLISLLLGLPLGVLTAIKRGKWYTEGLQFISIVGVSLPSFVVGILLILVFSVTFG 159
Cdd:PRK15081  81 MVSRRPVSEEIASRFMPTLWLTITSMVWAVIFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMQVFSVELG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 160 WLPAFGRGdvvqlGWWStglltpsgraaILLPSVALSLYQVTLVMRLVRAEMLEVLRSDYVKFARARGIPRWRIYFRHAL 239
Cdd:PRK15081 161 WLPTVGAD-----SWQH-----------YILPSLTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGL 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 240 RNCLMPVVTMTAMNVGSLIAFALITETVFQWPGMGMLFIQAVTFLDIPVMAAYLCIISFIFVVLNTLVDIAYAVIDPRLR 319
Cdd:PRK15081 225 RNAMIPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLYAAINPAIR 304
SapB COG4168
ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];
1-316 5.81e-55

ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];


Pssm-ID: 443329 [Multi-domain]  Cd Length: 321  Bit Score: 181.57  E-value: 5.81e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170   1 MLVFIIKRLANAVMVMLAVALLAFLIFRLagDPVEMMANEqmtqtdrdnlrerlglndGLMTQYTRFVVNAAQGNFGISY 80
Cdd:COG4168    1 MLIYLLRRLNLLLITLLILSLISFSLLYR--DPLNPLSDA------------------SLFSGYLFYLQNLLQGDFGISS 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170  81 RNGQDVLSLIAERFPATLELVLVATLISLLLGLPLGVLTAIKRGKWYTEGLQFISIVGVSLPSFVVGILLILVFSVTFGW 160
Cdd:COG4168   61 INGEPILEQLLTVFPATLELCFLAFLLALLIGIPLGILAGIYRGKWLDKLISSLSLLGFSIPVFWLALLLILFFSLNLGW 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 161 LPAFGRGDV---------VQL--GWWSTgllTPSGRAAI-------LLPSVALSLYQVTLVMRLVRAEMLEVLRSDYVKF 222
Cdd:COG4168  141 LPVSGRYNLlyeippvtgFALidAWLSD---SPYRLKAIqsalqhlILPTLVLAVAPTTEVIRLTRQSTEEVMNQNYIKA 217

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 223 ARARGIPRWRIYFRHALRNCLMPVVTMTAMNVGSLIAFALITETVFQWPGMGMLFIQAVTFLDIPVMAAYLCIISFIFVV 302
Cdd:COG4168  218 AATRGLSRFTIIRRHVLRNALPPIIPQLGLQFSTMLTLAMITEVVFSWPGIGRWLINAIRQQDYAAISAGVIVIGTFVII 297

                        330
                 ....*....|....
gi 490569170 303 LNTLVDIAYAVIDP 316
Cdd:COG4168  298 VNILSDILGALLNP 311
oppB PRK09471
oligopeptide ABC transporter permease OppB;
1-319 2.84e-52

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 174.10  E-value: 2.84e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170   1 MLVFIIKRLANAVMVMLAVALLAFLIFRLA-GDPV--------EMMANeqmtqtdrdnLRERLGLNDGLMTQYTRFVVNA 71
Cdd:PRK09471   1 MLKFILRRCLEAIPTLFILITISFFMMRLApGSPFtgertlppEVMAN----------IEAKYHLNDPIMTQYFSYLKQL 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170  72 AQGNFGISYR-NGQDVLSLIAERFPATLELVLVATLISLLLGLPLGVLTAIKRGKWYTEGLQFISIVGVSLPSFVVGILL 150
Cdd:PRK09471  71 AHGDFGPSFKyKDYSVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGFAMTGVVIPSFVVAPLL 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 151 ILVFSVTFGWLPAfgrgdvvqlGWWSTGlltpsGRAAILLPSVALSLYQVTLVMRLVRAEMLEVLRSDYVKFARARGIPR 230
Cdd:PRK09471 151 VLIFAITLHWLPG---------GGWNGG-----ALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPM 216

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 231 WRIYFRHALRNCLMPVVTMTAMNVGSLIAFALITETVFQWPGMGMLFIQAVTFLDIPVMAAYLCIISFIFVVLNTLVDIA 310
Cdd:PRK09471 217 RRIILRHALKPALLPVLSYMGPAFVGIITGSMVIETIFGLPGIGQLFVNGALNRDYSLVLSLTILVGALTILFNAIVDVL 296


                 ....*....
gi 490569170 311 YAVIDPRLR 319
Cdd:PRK09471 297 YAVIDPKIR 305
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
1-319 1.47e-51

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 173.46  E-value: 1.47e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170   1 MLVFIIKRLANAVMVMLAVALLAF-LIFRLAGDPVEMMANEQMTQTDRD-NLRERLGLNDGLMTQYTRFVVNAAQGNFGI 78
Cdd:PRK10914   1 MLQFILRRLGLVIPTFIGITLLTFaFVHMIPGDPVMIMAGERGISPERHaQLLAELGLDKPMWQQYLHYIWGVMHGDLGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170  79 SYRNGQDVLSLIAERFPATLELVLVATLISLLLGLPLGVLTAIKRGKWYTEGLQFISIVGVSLPSFVVGILLILVFSVTF 158
Cdd:PRK10914  81 SLKSRIPVWDEFVPRFKATLELGVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHW 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 159 GWLPAFGR-GDVVQLG---------------WWSTGLLTpSGRAAILLPSVALSLYQVTLVMRLVRAEMLEVLRSDYVKF 222
Cdd:PRK10914 161 NLTPVSGRvSDMVFLDdsnpltgfmlidtaiWGEDGNFI-DAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRT 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 223 ARARGIPRWRIYFRHALRNCLMPVVTMTAMNVGSLIAFALITETVFQWPGMGMLFIQAVTFLDIPVMAAYLCIISFIFVV 302
Cdd:PRK10914 240 ARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIIL 319

                        330
                 ....*....|....*..
gi 490569170 303 LNTLVDIAYAVIDPRLR 319
Cdd:PRK10914 320 VNLLVDLLYGVVNPRIR 336
PRK15110 PRK15110
peptide ABC transporter permease SapB;
73-316 3.91e-35

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 129.81  E-value: 3.91e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170  73 QGNFGISYRNGQDVLSLIAERFPATLELVLVATLISLLLGLPLGVLTAIKRGKWYTEGLQFISIVGVSLPSFVVGILLIL 152
Cdd:PRK15110  53 HWDFGVSSINGQPISEQLKEVFPATMELCILAFGFALLVGIPVGIIAGVTRHKWQDNLISALALLGFSIPVFWLALLLTL 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 153 VFSVTFGWLPAFGRGDVVQLGWWSTGL---------------LTPSGRAAILLPSVALSLYQVTLVMRLVRAEMLEVLRS 217
Cdd:PRK15110 133 FFSLTLGWLPVSGRFDLLYEVKPVTGFalidawlsdspwrdeMIMSAIRHMILPVITLAVAPTTEVIRLMRISTIEVYDQ 212

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 218 DYVKFARARGIPRWRIYFRHALRNCLMPVVTMTAMNVGSLIAFALITETVFQWPGMGMLFIQAVTFLDIPVMAAYLCIIS 297
Cdd:PRK15110 213 NYVKAAATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQDYAAISAGVMVVG 292

                        250
                 ....*....|....*....
gi 490569170 298 FIFVVLNTLVDIAYAVIDP 316
Cdd:PRK15110 293 SLVIIVNVLSDILGAMANP 311
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 119-319 8.20e-23

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 93.13  E-value: 8.20e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170  119 TAIKRGKWYTEGLQFISIVGVSLPSFVVGILLILVFsvtfgWLPAFGRGdvvqlgwwstglltpsgraaiLLPSVALSLY 198
Cdd:pfam00528   8 AALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIA-----ILSILGHG---------------------ILPAIILALL 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170  199 QVTLVMRLVRAEMLEVLRSDYVKFARARGIPRWRIYFRHALRNCLMPVVTMTAMNVGSLIAFALITETVFQWPGMGMLFI 278
Cdd:pfam00528  62 GWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLI 141

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 490569170  279 QAVTFLDIPVMAAYLCIISFIFVVLNTLVDIAYAVIDPRLR 319
Cdd:pfam00528 142 EAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 52-318 3.55e-22

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 95.20  E-value: 3.55e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170  52 ERLGLNDGLMTQYTRFVVNAAQGNFGISYRNGQDVLSLIAERFPATLELVLVATLISLLLGLPLGVLTAIKRGKWYTEGL 131
Cdd:PRK15133  91 HRYGFDKPLHERYFKMLWDYIRFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAVRNGSRFDVWS 170

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 132 QFISIVGVSLPSFVVGILLILVFS--VTFGWLPAFG--RGDVVQLGWWS--TGLLTpsgraAILLPSVALSLYQVTLVMR 205
Cdd:PRK15133 171 SAFIIIGYAIPAFLFAILLIVFFAggSYFDLFPLRGlvSANFDSLPWYQkiTDYLW-----HITLPVLATVIGGFAALTM 245

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 206 LVRAEMLEVLRSDYVKFARARGIPRWRIYFRHALRNCLMPVVT-MTAMNVGSLIAFALITETVFQWPGMGMLFIQAVTFL 284
Cdd:PRK15133 246 LTKNSFLDEIRKQYVVTARAKGVSEKNILWKHVFRNAMLLVIAgFPATFISMFFTGSLLIEVMFSLNGLGLLGYEATVSR 325

                        250       260       270
                 ....*....|....*....|....*....|....
gi 490569170 285 DIPVMAAYLCIISFIFVVLNTLVDIAYAVIDPRL 318
Cdd:PRK15133 326 DYPVMFGTLYIFTLIGLLLNIVSDISYTLVDPRI 359
BPD_transp_1_N pfam19300
Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal ...
 1-100 1.21e-12

Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal transmembrane domain of the Binding-protein-dependent transport system inner membrane component.


Pssm-ID: 437132 [Multi-domain]  Cd Length: 114  Bit Score: 63.39  E-value: 1.21e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170    1 MLVFIIKRLANAVMVMLAVALLAFLIFRLA-GDPVEMMANEQMTQTDRDNLRERLGLNDGLMTQYTRFVVN-------AA 72
Cdd:pfam19300   1 MLRFLVRRTLGAVVILLIISAVTFFLFYAIpRDPARLACGKNCTPETLALIRHNLGLDKPIPVQYWHFLSGifagrdfGA 80

                          90       100       110
                  ....*....|....*....|....*....|...
gi 490569170   73 QGN-----FGISYRNGQDVLSLIAERFPATLEL 100
Cdd:pfam19300  81 VGHcpapcLGYSFANNEPVWDTIMDRFPTTLSL 113
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 94-302 2.28e-11

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 61.91  E-value: 2.28e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170  94 FPATLELVLVATLISLLLGLPLGVLTAIKRGKWYTeGLQFISIVGVSLPSFVVGILLILVFSVTFGWLPAFGrgdvvqlg 173
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDR-LLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPG-------- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 174 wwstglltpsgraaILLPSVALSLYQVTLVMRLVRAEMLEVLRSDYVKFARARGIPRWRIYFRHALRNCLMPVVTMTAMN 253
Cdd:cd06261   72 --------------LGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLA 137

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 490569170 254 VGSLIAFALITETVF----QWPGMGMLFIQAVTFLDIPVMAAYLCIISFIFVV 302
Cdd:cd06261  138 FARALGEFALVSFLGggeaPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 193-258 5.92e-11

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 62.05  E-value: 5.92e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490569170 193 VALSLYQVTLVMRLVRAEMLEVLRSDYVKFARARGIPRWRIYFRHALRNCLMPVVTMTAMNVGSLI 258
Cdd:COG1173  146 LALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAI 211
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 206-249 2.63e-06

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 48.22  E-value: 2.63e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 490569170 206 LVRAEMLEVLRSDYVKFARARGIPRWRIYFRHALRNCLMPVVTM 249
Cdd:COG4239  221 VVRAEFLRARNLEYVRAARALGVSDRRIMFRHILPNAMVATLTF 264
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
186-261 9.57e-06

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 46.35  E-value: 9.57e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 186 AAILLPSV-----ALSLYQVTLVMRLVRAEMLEVLRSDYVKFARARGIPRWRIYFRHALRNCLMPVVTMTAMNVGSLIAF 260
Cdd:PRK09881 149 AAALGPSLfnamlAIAIVRIPFYVRLARGQALVVRQYTYVQAAKTFGASRWHLISWHILRNSLPPLIVQASLDIGSAILM 228


                 .
gi 490569170 261 A 261
Cdd:PRK09881 229 A 229
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 82-315 1.03e-04

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 43.43  E-value: 1.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170  82 NGQDVLSLIAERFPATLELVLVATLISLLLGLPLGVLTAIKRGKWYTEGLQFISiVGVSLPSFVVGILLILVFSVTFGWL 161
Cdd:PRK15021 128 NGGDVLARILYGTRISVLFGLMLTLCSSVMGVLAGALQGYYGGKVDLWGQRFIE-VWSGMPTLFLIILLSSVVQPNFWWL 206

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 162 PAFgrgdVVQLGWWStglltpsgraaillpsvalslyqvtlVMRLVRAEMLEVLRSDYVKFARARGIPRWRIYFRHALRN 241
Cdd:PRK15021 207 LAI----TVLFGWMS--------------------------LVGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPN 256

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 242 CLMPVVT---------MTAMNVGSLIAFALITETvfqwPGMGMLFIQAVTFLDIPvmaaYLCIISF--IFVVLNTLVDIA 310
Cdd:PRK15021 257 AMVATLTflpfilcssITTLTSLDFLGFGLPLGS----PSLGELLLQGKNNLQAP----WLGITAFlsVAILLSLLIFIG 328


                 ....*
gi 490569170 311 YAVID 315
Cdd:PRK15021 329 EAVRD 333
nikC PRK10417
nickel transporter permease NikC; Provisional
 137-258 2.92e-03

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 38.88  E-value: 2.92e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 137 VGVSLPSFVVGILLILVFSVTFGWLPAF--GRGDVVQLGWWSTGLLTPSGRAAILLPSV----------ALSLYQVTLVM 204
Cdd:PRK10417  66 TRVSLGSVMACLLLVLALGLVIGGSAGLlgGRVDQATMRVADMFMTFPTSILAFFMVGVlgtgltnviiAIALSHWAWYA 145

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 490569170 205 RLVRAEMLEVLRSDYVKFARARGIPRWRIYFRHALRNCLMPVVTMTAMNVGSLI 258
Cdd:PRK10417 146 RMVRSLVISLRQREFVLAARLSGAGHVRVFIDHLLPAVIPQLLVLATLDIGHMM 199
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 173-274 4.35e-03

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 38.17  E-value: 4.35e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490569170 173 GWWS-------------TGLLTPSGRAAILLPS-----VALSLYQVTLVMRLVRAEMLEVLRSDYVKFARARGIPRWRIY 234
Cdd:PRK15082 129 GWWDriimricdvlfafPGILLAIAVVAILGSGmanviIAVAIFSIPAFARLVRGNTLVLKQQTYIESARSIGASDWTIL 208

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 490569170 235 FRHALRNCLMPVVTMTAMNVGSLIafalITETVFQWPGMG 274
Cdd:PRK15082 209 LRHILPGTVSSIVVYFTMRIGTSI----ITAASLSFLGLG 244
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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