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Conserved domains on  [gi|490310106|ref|WP_004204824|]
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MULTISPECIES: exodeoxyribonuclease VII small subunit [Klebsiella]

Protein Classification

exodeoxyribonuclease VII small subunit( domain architecture ID 10011590)

small subunit of exodeoxyribonuclease VII, which degrades single-stranded DNA bidirectionally into nucleoside 5'-phosphates

EC:  3.1.11.6
Gene Ontology:  GO:0008855|GO:0004527|GO:0006308
PubMed:  6284744
SCOP:  4002913

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK00977 PRK00977
exodeoxyribonuclease VII small subunit; Provisional
 1-78 2.97e-28

exodeoxyribonuclease VII small subunit; Provisional


:

Pssm-ID: 179195  Cd Length: 80  Bit Score: 96.51  E-value: 2.97e-28
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490310106  1 MPKKNEAPASFETALGELEQIVNRLESGDLPLEEALSEFERGVQLARQGQSQLQQAEQRVQILL-ADSEDSPTTPFTPD 78
Cdd:PRK00977  2 MPAKKSKPLSFEEALAELEEIVTRLESGDLPLEESLAAFERGVALARQCQKKLQQAEQRVEKLLdEDGKEASLEPFDPD 80
 
Name Accession Description Interval E-value
PRK00977 PRK00977
exodeoxyribonuclease VII small subunit; Provisional
 1-78 2.97e-28

exodeoxyribonuclease VII small subunit; Provisional


Pssm-ID: 179195  Cd Length: 80  Bit Score: 96.51  E-value: 2.97e-28
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490310106  1 MPKKNEAPASFETALGELEQIVNRLESGDLPLEEALSEFERGVQLARQGQSQLQQAEQRVQILL-ADSEDSPTTPFTPD 78
Cdd:PRK00977  2 MPAKKSKPLSFEEALAELEEIVTRLESGDLPLEESLAAFERGVALARQCQKKLQQAEQRVEKLLdEDGKEASLEPFDPD 80
XseB COG1722
Exonuclease VII small subunit [Replication, recombination and repair];
5-78 1.28e-24

Exonuclease VII small subunit [Replication, recombination and repair];


Pssm-ID: 441328  Cd Length: 74  Bit Score: 87.21  E-value: 1.28e-24
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490310106  5 NEAPASFETALGELEQIVNRLESGDLPLEEALSEFERGVQLARQGQSQLQQAEQRVQILLADSEDSPTTPFTPD 78
Cdd:COG1722   1 DKKELSFEEALAELEEIVERLESGELPLEESLALYERGVALAKRCQKKLDEAEQKVEKLLEDEDGELEEPFDPE 74
xseB TIGR01280
exodeoxyribonuclease VII, small subunit; This protein is the small subunit for ...
 10-63 1.03e-17

exodeoxyribonuclease VII, small subunit; This protein is the small subunit for exodeoxyribonuclease VII. Exodeoxyribonuclease VII is made of a complex of four small subunits to one large subunit. The complex degrades single-stranded DNA into large acid-insoluble oligonucleotides. These nucleotides are then degraded further into acid-soluble oligonucleotides. [DNA metabolism, Degradation of DNA]


Pssm-ID: 273536  Cd Length: 54  Bit Score: 68.99  E-value: 1.03e-17
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 490310106  10 SFETALGELEQIVNRLESGDLPLEEALSEFERGVQLARQGQSQLQQAEQRVQIL 63
Cdd:TIGR01280  1 SFEEALAELEEIVEKLESGDLSLEESLKLYEEGIKLLKHCQKKLEEAEQKIEKL 54
Exonuc_VII_S pfam02609
Exonuclease VII small subunit; This family consist of exonuclease VII, small subunit EC:3.1.11. ...
 11-61 3.15e-17

Exonuclease VII small subunit; This family consist of exonuclease VII, small subunit EC:3.1.11.6 This enzyme catalyzes exonucleolytic cleavage in either 5'->3' or 3'->5' direction to yield 5'-phosphomononucleotides. This exonuclease VII enzyme is composed of one large subunit and 4 small ones.


Pssm-ID: 460618  Cd Length: 51  Bit Score: 67.79  E-value: 3.15e-17
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 490310106  11 FETALGELEQIVNRLESGDLPLEEALSEFERGVQLARQGQSQLQQAEQRVQ 61
Cdd:pfam02609  1 FEEALAELEEIVEKLESGELSLEESLKLYEEGIKLLKFCEKKLDEAEQKIE 51
 
Name Accession Description Interval E-value
PRK00977 PRK00977
exodeoxyribonuclease VII small subunit; Provisional
 1-78 2.97e-28

exodeoxyribonuclease VII small subunit; Provisional


Pssm-ID: 179195  Cd Length: 80  Bit Score: 96.51  E-value: 2.97e-28
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490310106  1 MPKKNEAPASFETALGELEQIVNRLESGDLPLEEALSEFERGVQLARQGQSQLQQAEQRVQILL-ADSEDSPTTPFTPD 78
Cdd:PRK00977  2 MPAKKSKPLSFEEALAELEEIVTRLESGDLPLEESLAAFERGVALARQCQKKLQQAEQRVEKLLdEDGKEASLEPFDPD 80
XseB COG1722
Exonuclease VII small subunit [Replication, recombination and repair];
5-78 1.28e-24

Exonuclease VII small subunit [Replication, recombination and repair];


Pssm-ID: 441328  Cd Length: 74  Bit Score: 87.21  E-value: 1.28e-24
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490310106  5 NEAPASFETALGELEQIVNRLESGDLPLEEALSEFERGVQLARQGQSQLQQAEQRVQILLADSEDSPTTPFTPD 78
Cdd:COG1722   1 DKKELSFEEALAELEEIVERLESGELPLEESLALYERGVALAKRCQKKLDEAEQKVEKLLEDEDGELEEPFDPE 74
xseB TIGR01280
exodeoxyribonuclease VII, small subunit; This protein is the small subunit for ...
 10-63 1.03e-17

exodeoxyribonuclease VII, small subunit; This protein is the small subunit for exodeoxyribonuclease VII. Exodeoxyribonuclease VII is made of a complex of four small subunits to one large subunit. The complex degrades single-stranded DNA into large acid-insoluble oligonucleotides. These nucleotides are then degraded further into acid-soluble oligonucleotides. [DNA metabolism, Degradation of DNA]


Pssm-ID: 273536  Cd Length: 54  Bit Score: 68.99  E-value: 1.03e-17
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 490310106  10 SFETALGELEQIVNRLESGDLPLEEALSEFERGVQLARQGQSQLQQAEQRVQIL 63
Cdd:TIGR01280  1 SFEEALAELEEIVEKLESGDLSLEESLKLYEEGIKLLKHCQKKLEEAEQKIEKL 54
Exonuc_VII_S pfam02609
Exonuclease VII small subunit; This family consist of exonuclease VII, small subunit EC:3.1.11. ...
 11-61 3.15e-17

Exonuclease VII small subunit; This family consist of exonuclease VII, small subunit EC:3.1.11.6 This enzyme catalyzes exonucleolytic cleavage in either 5'->3' or 3'->5' direction to yield 5'-phosphomononucleotides. This exonuclease VII enzyme is composed of one large subunit and 4 small ones.


Pssm-ID: 460618  Cd Length: 51  Bit Score: 67.79  E-value: 3.15e-17
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 490310106  11 FETALGELEQIVNRLESGDLPLEEALSEFERGVQLARQGQSQLQQAEQRVQ 61
Cdd:pfam02609  1 FEEALAELEEIVEKLESGELSLEESLKLYEEGIKLLKFCEKKLDEAEQKIE 51
PRK14066 PRK14066
exodeoxyribonuclease VII small subunit; Provisional
 7-78 3.31e-13

exodeoxyribonuclease VII small subunit; Provisional


Pssm-ID: 172556  Cd Length: 75  Bit Score: 58.31  E-value: 3.31e-13
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490310106  7 APASFETALGELEQIVNRLESGDLPLEEALSEFERGVQLARQGQSQLQQAEQRVQILLADSEDS-PTTPFTPD 78
Cdd:PRK14066  2 AVEKFETALKKLEEVVKKLEGGELSLDDSLKAFEEGVKHAAFCSKKLDEAERRVEVLLKQKDGSfVREPFRLD 74
PRK14063 PRK14063
exodeoxyribonuclease VII small subunit; Provisional
 5-80 3.83e-10

exodeoxyribonuclease VII small subunit; Provisional


Pssm-ID: 184483  Cd Length: 76  Bit Score: 50.60  E-value: 3.83e-10
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490310106  5 NEAPASFETALGELEQIVNRLESGDLPLEEALSEFERGVQLARQGQSQLQQAEQRVQILLadSEDSPTTPFTPDAE 80
Cdd:PRK14063  1 MENKLSFEEAISQLEHLVSKLEQGDVPLEEAISYFKEGMELSKLCDEKLKNVQEQMAVIL--GEDGELEPFTALGD 74
PRK14067 PRK14067
exodeoxyribonuclease VII small subunit; Provisional
 9-62 9.18e-09

exodeoxyribonuclease VII small subunit; Provisional


Pssm-ID: 172557  Cd Length: 80  Bit Score: 47.12  E-value: 9.18e-09
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 490310106  9 ASFETALGELEQIVNRLESGDLPLEEALSEFERGVQLARQGQSQLQQAEQRVQI 62
Cdd:PRK14067  7 ADFEQQLARLQEIVDALEGGDLPLEESVALYKEGLGLARACREQLAKARNEIRL 60
PRK14069 PRK14069
exodeoxyribonuclease VII small subunit; Provisional
 10-66 2.13e-08

exodeoxyribonuclease VII small subunit; Provisional


Pssm-ID: 172559  Cd Length: 95  Bit Score: 46.55  E-value: 2.13e-08
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 490310106 10 SFETALGELEQIVNRLESGDLPLEEALSEFERGVQLARQGQSQLQQAEQRVQILLAD 66
Cdd:PRK14069  9 SFEDALRELEQIAEKLERQDFSLEESLKAYERGMELKKICSGILDDAEGKIEALTKD 65
PRK14070 PRK14070
exodeoxyribonuclease VII small subunit; Provisional
 15-68 4.35e-08

exodeoxyribonuclease VII small subunit; Provisional


Pssm-ID: 184486  Cd Length: 69  Bit Score: 45.40  E-value: 4.35e-08
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 490310106 15 LGELEQIVNRLESGDLPLEEALSEFERGVQLARQGQSQLQQAEQRVQILLADSE 68
Cdd:PRK14070  1 MKELEEIVNRLENEDLPLEESIKLFERGVELYRKCKEILQQNRLKIIDVMKELE 54
PRK14064 PRK14064
exodeoxyribonuclease VII small subunit; Provisional
 10-80 3.37e-07

exodeoxyribonuclease VII small subunit; Provisional


Pssm-ID: 172554  Cd Length: 75  Bit Score: 43.28  E-value: 3.37e-07
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490310106 10 SFETALGELEQIVNRLESGDLPLEEALSEFERGVQLARQGQSQLQQAEQRVQILLadSEDSPTTPFTPDAE 80
Cdd:PRK14064  7 TFEEAIAELETIVEALENGSASLEDSLDMYQKGIELTKLCQDKLQSAEKRMAKVV--TDAGEEIPFEADGE 75
PRK14068 PRK14068
exodeoxyribonuclease VII small subunit; Provisional
 10-66 1.34e-05

exodeoxyribonuclease VII small subunit; Provisional


Pssm-ID: 184485  Cd Length: 76  Bit Score: 39.09  E-value: 1.34e-05
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 490310106 10 SFETALGELEQIVNRLESGDLPLEEALSEFERGVQLARQGQSQLQQAEQRVQILLAD 66
Cdd:PRK14068  7 SFEEMMQELEQIVQKLDNETVSLEESLDLYQRGMKLSAACDTTLKNAEKKVNDLIKE 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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