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Conserved domains on  [gi|490254990|ref|WP_004152946|]
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MULTISPECIES: ABC transporter permease [Klebsiella]

Protein Classification

ABC transporter permease( domain architecture ID 10003058)

ABC transporter permease is the transmembrane subunit found in a periplasmic binding protein (PBP)-dependent ABC transport system, which may be involved in the transport of one or more from a variety of substrates such as monosaccharide sugars such as xylose, arabinose, and fructose

Gene Ontology:  GO:0140359|GO:0042626
PubMed:  18535149|17723295|25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AraH COG1172
Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component ...
 9-339 5.31e-87

Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440785  Cd Length: 322  Bit Score: 264.66  E-value: 5.31e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990   9 SEGSSFFANLRHKMPKDTGIFVVMLVIALTFEIAgwyvrdQSFLLNTNRLVLIVLQVAIIGIIAVGVTQVIITTGIDLSS 88
Cdd:COG1172    2 SATTTTARSLLRRLLPELGLLLALVLLLVVFSIL------SPGFLSPGNLSNILRQAAILGILALGMTLVIITGGIDLSV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990  89 GSVIALAAVVAASLAQTSDslspmfpalvnLPAVIPICAGIGVGLLCGLTNGFLVTRTGIPPFIATLGMMVSARGLAQYY 168
Cdd:COG1172   76 GSVVALSGVVAALLLVALG-----------LPILLAILLALLVGALLGLLNGLLVAKLRIPPFIVTLGTMFIARGLALLL 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 169 TQGNPISFLSDSFTAIGQGA-----MPVIIFFVIAAVFHIALKHTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAG 243
Cdd:COG1172  145 TGGRPISGLPDAFRALGQGSllgipVPVLIALVVALVAWFLLRRTRFGRYIYAVGGNEEAARLSGINVRRVKILAYVLSG 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 244 ALSGLAGVVLAARVSSGQSSMGMSYELDAIAAAVIGGSSLMGGVGRITGTLIGAMILGLIKSGFTFVGVDAYVQDIIKGI 323
Cdd:COG1172  225 LLAGLAGILLAARLGSAQPNAGSGYELDAIAAVVIGGTSLTGGRGSVLGTLLGALILGVLNNGLNLLGVSSYWQQIVKGA 304

                        330
                 ....*....|....*.
gi 490254990 324 IIVAAVTIDMRRNRKK 339
Cdd:COG1172  305 IILLAVLLDRLRRRRR 320
 
Name Accession Description Interval E-value
AraH COG1172
Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component ...
 9-339 5.31e-87

Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440785  Cd Length: 322  Bit Score: 264.66  E-value: 5.31e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990   9 SEGSSFFANLRHKMPKDTGIFVVMLVIALTFEIAgwyvrdQSFLLNTNRLVLIVLQVAIIGIIAVGVTQVIITTGIDLSS 88
Cdd:COG1172    2 SATTTTARSLLRRLLPELGLLLALVLLLVVFSIL------SPGFLSPGNLSNILRQAAILGILALGMTLVIITGGIDLSV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990  89 GSVIALAAVVAASLAQTSDslspmfpalvnLPAVIPICAGIGVGLLCGLTNGFLVTRTGIPPFIATLGMMVSARGLAQYY 168
Cdd:COG1172   76 GSVVALSGVVAALLLVALG-----------LPILLAILLALLVGALLGLLNGLLVAKLRIPPFIVTLGTMFIARGLALLL 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 169 TQGNPISFLSDSFTAIGQGA-----MPVIIFFVIAAVFHIALKHTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAG 243
Cdd:COG1172  145 TGGRPISGLPDAFRALGQGSllgipVPVLIALVVALVAWFLLRRTRFGRYIYAVGGNEEAARLSGINVRRVKILAYVLSG 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 244 ALSGLAGVVLAARVSSGQSSMGMSYELDAIAAAVIGGSSLMGGVGRITGTLIGAMILGLIKSGFTFVGVDAYVQDIIKGI 323
Cdd:COG1172  225 LLAGLAGILLAARLGSAQPNAGSGYELDAIAAVVIGGTSLTGGRGSVLGTLLGALILGVLNNGLNLLGVSSYWQQIVKGA 304

                        330
                 ....*....|....*.
gi 490254990 324 IIVAAVTIDMRRNRKK 339
Cdd:COG1172  305 IILLAVLLDRLRRRRR 320
TM_PBP1_transp_AraH_like cd06579
Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the ...
 65-332 2.09e-72

Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group also contains E. coli RbsC, AlsC, and MglC, which are TMs of other monosaccharide transporters, the ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also be involved in low affinity ribose transport. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Proteins in this subgroup have a single TM which homodimerizes to generate the transmembrane pore.


Pssm-ID: 119321 [Multi-domain]  Cd Length: 263  Bit Score: 225.37  E-value: 2.09e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990  65 VAIIGIIAVGVTQVIITTGIDLSSGSVIALAAVVAASLAQTSDslspmfpalvnLPAVIPICAGIGVGLLCGLTNGFLVT 144
Cdd:cd06579    1 AAVLGILALGMTLVIITGGIDLSVGSVAALSAVVAALLLVNAG-----------LPIPLAILAALAVGALIGLLNGLLVA 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 145 RTGIPPFIATLGMMVSARGLAQYYTQGNPISFLSDSFTAIGQGA------MPVIIFFVIAAVFHIALKHTRYGKYVYAIG 218
Cdd:cd06579   70 YLRIPPFIVTLGTMFILRGLALLITGGRPISGLPPLFSFFLGGGlilgipVPVLIALAVALVAWFLLRRTRFGRYLYAVG 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 219 GNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVVLAARVSSGQSSMGMSYELDAIAAAVIGGSSLMGGVGRITGTLIGAM 298
Cdd:cd06579  150 GNPEAARLSGINVRRVKILAYVLSGLLAGLAGILLAARLGSAQPTAGNGYELDAIAAVVLGGTSLTGGRGSVLGTLLGAL 229

                        250       260       270
                 ....*....|....*....|....*....|....
gi 490254990 299 ILGLIKSGFTFVGVDAYVQDIIKGIIIVAAVTID 332
Cdd:cd06579  230 LLGVLNNGLNLLGVSSFWQQIVKGAILLLAVALD 263
mglC PRK09478
galactose/methyl galactoside ABC transporter permease MglC;
24-339 3.23e-66

galactose/methyl galactoside ABC transporter permease MglC;


Pssm-ID: 181892 [Multi-domain]  Cd Length: 336  Bit Score: 211.85  E-value: 3.23e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990  24 KDTGIFVVMLVIaltfeIAGWYVRDQSFLlNTNRLVLIVLQVAIIGIIAVGVTQVIITTGIDLSSGSVIALAAVVAASLA 103
Cdd:PRK09478  14 KEGGIYVVLLVL-----LAIIIIQDPTFL-SLLNLSNILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAAVVAATLL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 104 QTSDSLSPMFPALVNLPAVIPICAGIGVGLLCGLTNGFLVTRTGIPPFIATLGMMVSARGLAQYYTQ---GNPISFLSDS 180
Cdd:PRK09478  88 QSMDNANKVFPELATMPIALVILIVCAIGAVIGLINGLIIAYLNVTPFIATLGTMIIVYGINSLYYDfvgASPISGFDSG 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 181 FTAIGQG-------AMPVIIFFVIAAVFHI--ALKHTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGV 251
Cdd:PRK09478 168 FSTFAQGfvalgsfRLSYITFYALIAVAFVwvLWNKTRFGKNIFAIGGNPEAAKVSGVNVPLNLLMIYALSGVFYAFGGM 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 252 VLAARVSSGQSSMGMSYELDAIAAAVIGGSSLMGGVGRITGTLIGAMILGLIKSGFTFVGVDAYVQDIIKGIIIVAAVTI 331
Cdd:PRK09478 248 LEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAIIIFAVAL 327


                 ....*...
gi 490254990 332 DMRRNRKK 339
Cdd:PRK09478 328 DSLKYARK 335
GguB NF040906
sugar ABC transporter permease;
27-338 3.86e-40

sugar ABC transporter permease;


Pssm-ID: 468841 [Multi-domain]  Cd Length: 375  Bit Score: 144.91  E-value: 3.86e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990  27 GIFVVMLVIALTFEIAgwyvrDQSFLLNTNRLVLIVLQVAIIGIIAVGVTQVIITTGIDLSSGSVIALAAVVAASLAQTS 106
Cdd:NF040906   6 GMLIALVAIVVLFQIL-----TGGILLRPLNVTNLILQNSYILILAIGMLLVIIAGHIDLSVGSVVAFVGAVAAVLMVNW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 107 DslspmfpalVNLPAVIPICagIGVGLLCGLTNGFLVTRTGIPPFIATLGMMVSARGLAQYYTQGNPISFLSDSFTAIGQ 186
Cdd:NF040906  81 G---------MPWWLAVLLC--LLVGALIGAWQGFWVAYVGIPAFIVTLAGMLVFRGLTLVVLGGQSIGPFPDGFQKISS 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 187 GAMP--------------------------------------------------------VIIFF--------------- 195
Cdd:NF040906 150 GFLPdlfggtglhlltlllgvlaaaalvwsqlrgrrrrikyglevepmalfiaklvliaaAILFFtyllasyrglpnvli 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 196 ---VIAAVFHIALKHTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVVLAARVSSGQSSMGMSYELDA 272
Cdd:NF040906 230 ilgVLILVYSFVTNRTVIGRHIYAVGGNEKAAKLSGIKTKRVTFLVFVNMGVLAALAGLVFAARLNSATPKAGNGFELDA 309

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490254990 273 IAAAVIGGSSLMGGVGRITGTLIGAMILGLIKSGFTFVGVDAYVQDIIKGIIIVAAVTIDMRRNRK 338
Cdd:NF040906 310 IAACFIGGASASGGVGTVVGAIIGALVMGVLNNGMSILGIGIDWQQVIKGLVLLAAVAFDVYNKRK 375
BPD_transp_2 pfam02653
Branched-chain amino acid transport system / permease component; This is a large family mainly ...
 58-329 2.77e-23

Branched-chain amino acid transport system / permease component; This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as E. coli LivH and LivM, both of which are form the LIV-I transport system. Also found with in this family are proteins from the galactose transport system permease and a ribose transport system.


Pssm-ID: 396977 [Multi-domain]  Cd Length: 269  Bit Score: 96.94  E-value: 2.77e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990   58 LVLIVLQVAIIGIIAVGVTQVIITTG-IDLSSGSVIALAAVVAASLAQtsdslspmfPALVNLPAVIPicAGIGVGLLCG 136
Cdd:pfam02653   2 ILNILTLASIYAIAALGLTLIYGIAGvINLGHGGFMMLGAYVAAMLLN---------LLGPGLWLALP--VGILVGAAVG 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990  137 LTNGFLVTRTGIPPFIATLGMMVSARGLAQYYTQG----------NPISFLSDSFTAIGQGAMPVIIFFVIAAVFHIALK 206
Cdd:pfam02653  71 LLIGILTLRLKINEVIITLLLNLAALGLALFLVTGilggeggtsgITGPSGFPGAFLSFAFAFIFLLALLLVLALWLLLY 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990  207 HTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVVLAAR-VSSGQSSMGMSYELDAIAAAVIggsslmG 285
Cdd:pfam02653 151 RTKFGRALRAVGENEEAARAAGINVKKLKLLTFVISGALAGLAGALLALYtGVVPPSNFGVGLGLDAIAAVVL------G 224

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 490254990  286 GVGRITGTLIGAMILGLIKS-GFTFVGVDAYVQDIIKGIIIVAAV 329
Cdd:pfam02653 225 GAGSPIGVVIGSLIIGLVQSlGLGALGSPPELSLLVLGALLILVL 269
 
Name Accession Description Interval E-value
AraH COG1172
Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component ...
 9-339 5.31e-87

Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440785  Cd Length: 322  Bit Score: 264.66  E-value: 5.31e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990   9 SEGSSFFANLRHKMPKDTGIFVVMLVIALTFEIAgwyvrdQSFLLNTNRLVLIVLQVAIIGIIAVGVTQVIITTGIDLSS 88
Cdd:COG1172    2 SATTTTARSLLRRLLPELGLLLALVLLLVVFSIL------SPGFLSPGNLSNILRQAAILGILALGMTLVIITGGIDLSV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990  89 GSVIALAAVVAASLAQTSDslspmfpalvnLPAVIPICAGIGVGLLCGLTNGFLVTRTGIPPFIATLGMMVSARGLAQYY 168
Cdd:COG1172   76 GSVVALSGVVAALLLVALG-----------LPILLAILLALLVGALLGLLNGLLVAKLRIPPFIVTLGTMFIARGLALLL 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 169 TQGNPISFLSDSFTAIGQGA-----MPVIIFFVIAAVFHIALKHTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAG 243
Cdd:COG1172  145 TGGRPISGLPDAFRALGQGSllgipVPVLIALVVALVAWFLLRRTRFGRYIYAVGGNEEAARLSGINVRRVKILAYVLSG 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 244 ALSGLAGVVLAARVSSGQSSMGMSYELDAIAAAVIGGSSLMGGVGRITGTLIGAMILGLIKSGFTFVGVDAYVQDIIKGI 323
Cdd:COG1172  225 LLAGLAGILLAARLGSAQPNAGSGYELDAIAAVVIGGTSLTGGRGSVLGTLLGALILGVLNNGLNLLGVSSYWQQIVKGA 304

                        330
                 ....*....|....*.
gi 490254990 324 IIVAAVTIDMRRNRKK 339
Cdd:COG1172  305 IILLAVLLDRLRRRRR 320
TM_PBP1_transp_AraH_like cd06579
Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the ...
 65-332 2.09e-72

Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group also contains E. coli RbsC, AlsC, and MglC, which are TMs of other monosaccharide transporters, the ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also be involved in low affinity ribose transport. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Proteins in this subgroup have a single TM which homodimerizes to generate the transmembrane pore.


Pssm-ID: 119321 [Multi-domain]  Cd Length: 263  Bit Score: 225.37  E-value: 2.09e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990  65 VAIIGIIAVGVTQVIITTGIDLSSGSVIALAAVVAASLAQTSDslspmfpalvnLPAVIPICAGIGVGLLCGLTNGFLVT 144
Cdd:cd06579    1 AAVLGILALGMTLVIITGGIDLSVGSVAALSAVVAALLLVNAG-----------LPIPLAILAALAVGALIGLLNGLLVA 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 145 RTGIPPFIATLGMMVSARGLAQYYTQGNPISFLSDSFTAIGQGA------MPVIIFFVIAAVFHIALKHTRYGKYVYAIG 218
Cdd:cd06579   70 YLRIPPFIVTLGTMFILRGLALLITGGRPISGLPPLFSFFLGGGlilgipVPVLIALAVALVAWFLLRRTRFGRYLYAVG 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 219 GNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVVLAARVSSGQSSMGMSYELDAIAAAVIGGSSLMGGVGRITGTLIGAM 298
Cdd:cd06579  150 GNPEAARLSGINVRRVKILAYVLSGLLAGLAGILLAARLGSAQPTAGNGYELDAIAAVVLGGTSLTGGRGSVLGTLLGAL 229

                        250       260       270
                 ....*....|....*....|....*....|....
gi 490254990 299 ILGLIKSGFTFVGVDAYVQDIIKGIIIVAAVTID 332
Cdd:cd06579  230 LLGVLNNGLNLLGVSSFWQQIVKGAILLLAVALD 263
mglC PRK09478
galactose/methyl galactoside ABC transporter permease MglC;
24-339 3.23e-66

galactose/methyl galactoside ABC transporter permease MglC;


Pssm-ID: 181892 [Multi-domain]  Cd Length: 336  Bit Score: 211.85  E-value: 3.23e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990  24 KDTGIFVVMLVIaltfeIAGWYVRDQSFLlNTNRLVLIVLQVAIIGIIAVGVTQVIITTGIDLSSGSVIALAAVVAASLA 103
Cdd:PRK09478  14 KEGGIYVVLLVL-----LAIIIIQDPTFL-SLLNLSNILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAAVVAATLL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 104 QTSDSLSPMFPALVNLPAVIPICAGIGVGLLCGLTNGFLVTRTGIPPFIATLGMMVSARGLAQYYTQ---GNPISFLSDS 180
Cdd:PRK09478  88 QSMDNANKVFPELATMPIALVILIVCAIGAVIGLINGLIIAYLNVTPFIATLGTMIIVYGINSLYYDfvgASPISGFDSG 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 181 FTAIGQG-------AMPVIIFFVIAAVFHI--ALKHTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGV 251
Cdd:PRK09478 168 FSTFAQGfvalgsfRLSYITFYALIAVAFVwvLWNKTRFGKNIFAIGGNPEAAKVSGVNVPLNLLMIYALSGVFYAFGGM 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 252 VLAARVSSGQSSMGMSYELDAIAAAVIGGSSLMGGVGRITGTLIGAMILGLIKSGFTFVGVDAYVQDIIKGIIIVAAVTI 331
Cdd:PRK09478 248 LEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAIIIFAVAL 327


                 ....*...
gi 490254990 332 DMRRNRKK 339
Cdd:PRK09478 328 DSLKYARK 335
XylH COG4214
ABC-type xylose transport system, permease component [Carbohydrate transport and metabolism];
1-338 9.53e-63

ABC-type xylose transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443360 [Multi-domain]  Cd Length: 393  Bit Score: 204.58  E-value: 9.53e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990   1 MKLTAAPASEGSSFFANLRHKMpKDTGIFVVMLVIALTFEIAgwyvRDQSFLLNTNrLVLIVLQVAIIGIIAVGVTQVII 80
Cdd:COG4214    1 MSTTAAPGGAVRSLRRLLGGDL-RSLGMIIALVVIWIVFQIL----TGGTFLTPRN-LSNLLLQNSYIGILAIGMVLVIL 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990  81 TTGIDLSSGSVIALAAvvaaslaqtsdSLSPMFPALVNLPAVIPICAGIGVGLLCGLTNGFLVTRTGIPPFIATLGMMVS 160
Cdd:COG4214   75 LGHIDLSVGSVSGFVG-----------AVAAVLMVNWGLPWWLAILAALLVGALIGAWQGFWVAYVGIPSFIVTLAGMLA 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 161 ARGLAQYYTQGNPISFLSDSFTAIGQGAMP-------------------------------------------------- 190
Cdd:COG4214  144 FRGLTLLVLGGGTIAPFDPTFQAIGNGFLPdilgtlswvlgavavaayvalqlrsrrrrrryglpveplwlfvlklalla 223

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 191 -------------------VIIFFVIAAVFHIALKHTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGV 251
Cdd:COG4214  224 vlilgavyllnsyrgipivVLILLVLVVVYTFVLTRTVFGRHIYAVGGNPEAARLSGINVRRVTFSVFVNMGVLAALAGI 303

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 252 VLAARVSSGQSSMGMSYELDAIAAAVIGGSSLMGGVGRITGTLIGAMILGLIKSGFTFVGVDAYVQDIIKGIIIVAAVTI 331
Cdd:COG4214  304 VFAARLNSATPSAGTGFELDAIAAAVIGGTSLFGGVGTVYGAVIGALVMGSLNNGMSLLGVDSDWQQIVKGLVLLLAVAF 383


                 ....*....
gi 490254990 332 DM--RRNRK 338
Cdd:COG4214  384 DVlsRRRRG 392
COG4158 COG4158
Predicted ABC-type sugar transport system, permease component [General function prediction ...
 27-339 1.75e-60

Predicted ABC-type sugar transport system, permease component [General function prediction only];


Pssm-ID: 443324  Cd Length: 334  Bit Score: 197.07  E-value: 1.75e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990  27 GIFVVMLVIALTFEIAGwyvrdqSFLLNTNRLVLIVLQVAIIGIIAVGVTQVIITTGIDLSSGSVIalaavvaaslaqts 106
Cdd:COG4158   31 GMLPVLILLCIGFELLT------PNFLTVQNLSNIARQASINIVLAAGMTFVILTGGIDLSVGSIL-------------- 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 107 dSLSPMFPALVNL---PAVIPICAGIGVGLLCGLTNGFLVTRTGIPPFIATLGMMVSARGLAQYYTQGNPISFLSDSFTA 183
Cdd:COG4158   91 -AASAVVAVLVSLlpgLGLLGIPAALLVGLLFGLINGLLIAFLKLPPFIVTLGSLTALRGAARLLANGTTVFNPDLPFAW 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 184 IGQGAM-----PVIIFFVIAAVFHIALKHTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVVLAARVS 258
Cdd:COG4158  170 IGNGYLlgipwLVVIALAVVLASWFILRRTVLGVHIYAVGGNAQAARLTGIKVWRVLLFVYAVSGLLAGLGGVMSAARLY 249

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 259 SGQSSMG-MSYELDAIAAAVIGGSSLMGGVGRITGTLIGAMILGLIKSGFTFVGVDAYVQDIIKGIIIVAAVTIDMRRNR 337
Cdd:COG4158  250 AANGLQLgQGYELDAIAAVILGGTSFVGGIGSIWGTLIGALIIAVLNNGLILLGVSDFWQFIIKGLVIIIAVALDRYRQR 329


                 ..
gi 490254990 338 KK 339
Cdd:COG4158  330 GS 331
rbsC PRK09512
ribose ABC transporter permease protein; Reviewed
 34-332 6.56e-58

ribose ABC transporter permease protein; Reviewed


Pssm-ID: 181922 [Multi-domain]  Cd Length: 320  Bit Score: 189.93  E-value: 6.56e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990  34 VIALTFEIAGWYVRDQSFLlNTNRLVLIVLQVAIIGIIAVGVTQVIITTGIDLSSGSVIALAAVVAASLAQTsdslspmf 113
Cdd:PRK09512  22 LIALLVLIAIVSTLSPNFF-TVNNLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAASIVGI-------- 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 114 palvNLPAVIPICAGIGVGLLCGLTNGFLVTRTGIPPFIATLGMMVSARGLAQYYTQGNPISF----LSDSFTAIGQG-- 187
Cdd:PRK09512  93 ----EVNALVAVPAALALGAAIGAVTGVIVAKGKVQAFIATLVMMLLLRGVTMVYTDGSPINTgftdNADLFGWFGIGrp 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 188 ---AMPVIIFFVIAAVFHIALKHTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVVLAARVSSGQSSM 264
Cdd:PRK09512 169 lgiPTPVWIMAIVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNKVKIIVYALCGLLAALAGIIEVARLSSAQPTA 248

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490254990 265 GMSYELDAIAAAVIGGSSLMGGVGRITGTLIGAMILGLIKSGFTFVGVDAYVQDIIKGIIIVAAVTID 332
Cdd:PRK09512 249 GTGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLVD 316
PRK09699 PRK09699
D-allose ABC transporter permease;
27-332 3.56e-45

D-allose ABC transporter permease;


Pssm-ID: 182035 [Multi-domain]  Cd Length: 312  Bit Score: 156.47  E-value: 3.56e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990  27 GIFVVMLVIALTFEIAgwyvrDQSFLLNTNRLVLIVLQVAIIGIIAVGVTQVIITTGIDLSSGSVIalaavvaaslaqts 106
Cdd:PRK09699  13 GTFFILAIIVAIFGSL-----SPEYFLTTNNITQIFVQSSVTVLIGMGEFFAILVAGIDLSVGAIL-------------- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 107 dSLSPMFPALVNLPAVIPICA----GIGVGLLCGLTNGFLVTRTGIPPFIATLGMMVSARGLAQYYTQGNPISFLSDSFT 182
Cdd:PRK09699  74 -ALSGMVTAKLMLAGVDPFLAaligGVLVGGALGAINGCLVNWTGLHPFIITLGTNAIFRGITLVISDANSVYGFSFDFV 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 183 AIGQGAM-----PVIIFFVIAAVFHIALKHTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVVLAARV 257
Cdd:PRK09699 153 NFFAASVigipvPVIFSLIVALILWFLTTRMRLGRNIYALGGNKNSAFYSGIDVKFHILVVFIISGVCAGLAGVVSTARL 232

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490254990 258 SSGQSSMGMSYELDAIAAAVIGGSSLMGGVGRITGTLIGAMILGLIKSGFTFVGVDAYVQDIIKGIIIVAAVTID 332
Cdd:PRK09699 233 GAAEPLAGMGFETYAIASAIIGGTSFFGGKGRIFSVVIGGLIIGTINNGLNILQVQTYYQLVVMGGLIIAAVALD 307
araH PRK11285
L-arabinose transporter permease protein; Provisional
 63-339 1.15e-40

L-arabinose transporter permease protein; Provisional


Pssm-ID: 183076 [Multi-domain]  Cd Length: 333  Bit Score: 145.21  E-value: 1.15e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990  63 LQVAIIGIIAVGVTQVIITTGIDLSSGSVIALAAVVAASLAQTSDSLspmfpalvnlpaVIPICAGIGVGLLCGLTNGFL 142
Cdd:PRK11285  61 LAISMIGMVACTMLFCLASGDFDLSVASVVAFAGVVTAVVINATESL------------WLGVAAGLLLGAAVGLVNGFV 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 143 VTRTGIPPFIATLGMMVSARGLAQYYTQGNPISFLSDSFTAIGQGAM-----PVIIFFVIAAVFHIALKHTRYGKYVYAI 217
Cdd:PRK11285 129 IARLKINALITTLATMQIVRGLAYIISDGKAVGISDERFFALGYANFfgvpaPIWLTVACFVVFGFLLNKTTFGRNTLAI 208

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 218 GGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVVLAARVSSGQSSMGMSYELDAIAAAVIGGSSLMGGVGRITGTLIGA 297
Cdd:PRK11285 209 GGNEEAARLAGVPVVRTKIIIFVLQGLVSALAGVILASRMTSGQPMTSIGFELIVISACVLGGVSLKGGIAKISGVVAGV 288

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 490254990 298 MILGLIKSGFTFVGVDAYVQDIIKGIIIVAAVTIDMRRNRKK 339
Cdd:PRK11285 289 LILGTVENAMNLLNISPFYQYVVRGLILLAAVLFDRYKQRAK 330
GguB NF040906
sugar ABC transporter permease;
27-338 3.86e-40

sugar ABC transporter permease;


Pssm-ID: 468841 [Multi-domain]  Cd Length: 375  Bit Score: 144.91  E-value: 3.86e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990  27 GIFVVMLVIALTFEIAgwyvrDQSFLLNTNRLVLIVLQVAIIGIIAVGVTQVIITTGIDLSSGSVIALAAVVAASLAQTS 106
Cdd:NF040906   6 GMLIALVAIVVLFQIL-----TGGILLRPLNVTNLILQNSYILILAIGMLLVIIAGHIDLSVGSVVAFVGAVAAVLMVNW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 107 DslspmfpalVNLPAVIPICagIGVGLLCGLTNGFLVTRTGIPPFIATLGMMVSARGLAQYYTQGNPISFLSDSFTAIGQ 186
Cdd:NF040906  81 G---------MPWWLAVLLC--LLVGALIGAWQGFWVAYVGIPAFIVTLAGMLVFRGLTLVVLGGQSIGPFPDGFQKISS 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 187 GAMP--------------------------------------------------------VIIFF--------------- 195
Cdd:NF040906 150 GFLPdlfggtglhlltlllgvlaaaalvwsqlrgrrrrikyglevepmalfiaklvliaaAILFFtyllasyrglpnvli 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 196 ---VIAAVFHIALKHTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVVLAARVSSGQSSMGMSYELDA 272
Cdd:NF040906 230 ilgVLILVYSFVTNRTVIGRHIYAVGGNEKAAKLSGIKTKRVTFLVFVNMGVLAALAGLVFAARLNSATPKAGNGFELDA 309

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490254990 273 IAAAVIGGSSLMGGVGRITGTLIGAMILGLIKSGFTFVGVDAYVQDIIKGIIIVAAVTIDMRRNRK 338
Cdd:NF040906 310 IAACFIGGASASGGVGTVVGAIIGALVMGVLNNGMSILGIGIDWQQVIKGLVLLAAVAFDVYNKRK 375
PRK11618 PRK11618
inner membrane ABC transporter permease protein YjfF; Provisional
 66-311 4.01e-31

inner membrane ABC transporter permease protein YjfF; Provisional


Pssm-ID: 183235 [Multi-domain]  Cd Length: 317  Bit Score: 119.29  E-value: 4.01e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990  66 AIIGIIAVGVTQVIITTGIDLSSGSVIALAAVVAASLAQTSDslspmFPALVNLPAVIPICAGIGVGLlcgltnGFLVTR 145
Cdd:PRK11618  43 AFLGIVAVGMTFVILSGGIDLSVGSVIAFTGVFLAKLIGDYG-----WSPLLAFPLVLVMGAAFGAFM------GALIHY 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 146 TGIPPFIATLGMMVSARGLAQYY-TQGNPI-----SFLSDSFTAIGQGAM---PVIIFFVIAAVFHIALKHTRYGKYVYA 216
Cdd:PRK11618 112 LKLPAFIVTLAGMFLARGVSFLVsEESIPInhpfyDTLSSLAWKLPGGGRlsaMALIMLAVVAIGIFLAHRTRFGNNVYA 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 217 IGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVVLAARVSSGQSSMGMSYELDAIAAAVIGGSSLMGGVGRITGTLIG 296
Cdd:PRK11618 192 IGGNATSANLMGIPVRRTTIRIYMLSGFLATLAGIVFSLYTSAGYALAAVGVELDAIAAVVIGGTLLTGGVGTVLGTLFG 271

                        250
                 ....*....|....*
gi 490254990 297 AMILGLIKSGFTFVG 311
Cdd:PRK11618 272 VLIQGLIQTYITFDG 286
PRK15432 PRK15432
autoinducer 2 ABC transporter permease LsrC; Provisional
 31-334 1.28e-26

autoinducer 2 ABC transporter permease LsrC; Provisional


Pssm-ID: 185330 [Multi-domain]  Cd Length: 344  Bit Score: 107.89  E-value: 1.28e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990  31 VMLVIALTFEIAGwYVRDQSFLLNTnrLVLIVLQVAIIGIIAVGVTQVIITTGIDLSSGSVIALAAVVAASLAQTSDSLS 110
Cdd:PRK15432  13 ALLAIVLLFVLLG-FLDRQYLSLQT--LTMVFSSAQILILLAIGATLVMLTRNIDVSVGSITGLCAVLVGMLLNAGYSLP 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 111 pmfpalvnlpavIPICAGIGVGLLCGLTNGFLVTRTGIPPFIATLGMMVSARGLAQYYTQGNPISFLSDSF------TAI 184
Cdd:PRK15432  90 ------------VACLATLLLGLLAGFFNGVLVAWLRIPAIVATLGTLGLYRGIMLLWTGGKWIEGLPAELkqlsapILL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 185 GQGAMPVIIFFVIAAVFHIaLKHTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVVLAARVSSGQSSM 264
Cdd:PRK15432 158 GISPIGWLTLILILAMAWL-LAKTAFGRSFYATGDNLQGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQIGFIPNQT 236

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 265 GMSYELDAIAAAVIGGSSLMGGVGRITGTLIGAMILGLIKSGFTFVGVDAYVQDIIKGIIIVAAVTIDMR 334
Cdd:PRK15432 237 GTGLEMKAIAACVLGGISLLGGSGTIIGAVLGAYFLTQIDSVLVLLRIPAWWNDFIAGLVLLGVLVFDGR 306
BPD_transp_2 pfam02653
Branched-chain amino acid transport system / permease component; This is a large family mainly ...
 58-329 2.77e-23

Branched-chain amino acid transport system / permease component; This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as E. coli LivH and LivM, both of which are form the LIV-I transport system. Also found with in this family are proteins from the galactose transport system permease and a ribose transport system.


Pssm-ID: 396977 [Multi-domain]  Cd Length: 269  Bit Score: 96.94  E-value: 2.77e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990   58 LVLIVLQVAIIGIIAVGVTQVIITTG-IDLSSGSVIALAAVVAASLAQtsdslspmfPALVNLPAVIPicAGIGVGLLCG 136
Cdd:pfam02653   2 ILNILTLASIYAIAALGLTLIYGIAGvINLGHGGFMMLGAYVAAMLLN---------LLGPGLWLALP--VGILVGAAVG 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990  137 LTNGFLVTRTGIPPFIATLGMMVSARGLAQYYTQG----------NPISFLSDSFTAIGQGAMPVIIFFVIAAVFHIALK 206
Cdd:pfam02653  71 LLIGILTLRLKINEVIITLLLNLAALGLALFLVTGilggeggtsgITGPSGFPGAFLSFAFAFIFLLALLLVLALWLLLY 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990  207 HTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVVLAAR-VSSGQSSMGMSYELDAIAAAVIggsslmG 285
Cdd:pfam02653 151 RTKFGRALRAVGENEEAARAAGINVKKLKLLTFVISGALAGLAGALLALYtGVVPPSNFGVGLGLDAIAAVVL------G 224

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 490254990  286 GVGRITGTLIGAMILGLIKS-GFTFVGVDAYVQDIIKGIIIVAAV 329
Cdd:pfam02653 225 GAGSPIGVVIGSLIIGLVQSlGLGALGSPPELSLLVLGALLILVL 269
PRK15038 PRK15038
autoinducer 2 ABC transporter permease LsrD;
52-329 3.83e-23

autoinducer 2 ABC transporter permease LsrD;


Pssm-ID: 184998  Cd Length: 330  Bit Score: 97.98  E-value: 3.83e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990  52 LLNTNRLVLIVLQVAIIGIIAVGVTQVIITTGIDLSSGSVIALaavvaaslaqTSDSLSPMFPALVNLPAVIPICagIGV 131
Cdd:PRK15038  29 MLDINVLLFSTSDFICIGIVALPLTMVIVSGGIDISFGSTIGL----------CAIALGVLFQSGVPMPLAILLT--LLL 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 132 GLLCGLTNGFLVTRTGIPPFIATLGMMVSARGLAQYYTQ-----------GNPISFLSDSFTAIGQGAMPVIIFFVIAAV 200
Cdd:PRK15038  97 GALCGLINAGLIIYTGVNPLVITLGTLYLFGGSALLLSGmagatgyegigGFPMAFTDFANLDVLGLPVPLIIFLICLLV 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 201 FHIALKHTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVVLAARVSSGQSSMGMSYELDAIAAAVIGG 280
Cdd:PRK15038 177 FWLLMHRTHAGRNVFLIGQSPRVALYSAIPVNRTLCALYAMTGLASAIAAVLLVSYFGSARSDLGASFLMPAITAVVLGG 256

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 490254990 281 SSLMGGVGRITGTLIGAMILGLIKSGFTFVGVDAYVQDIIKGIIIVAAV 329
Cdd:PRK15038 257 ANIYGGSGSIIGTALAVLLVGYLQQGLQMAGVPNQISSALSGALLIVVV 305
TM_PBP1_branched-chain-AA_like cd06574
Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette ...
 127-329 4.72e-19

Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of monosaccharides including ribose, galactose, and arabinose. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. This group includes Escherichia coli LivM and LivH, two TMs which heterodimerize to form the translocation pathway of the E. coli branched-chain AA LIV-1/LS transporter. This transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) and LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine. Included in this group are proteins from transport systems that contain a single TM which homodimerizes to generate the transmembrane pore; for example E. coli RbsC, AlsC, and MglC, the TMs of the high affinity ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also to be involved in low affinity ribose transport.


Pssm-ID: 119320 [Multi-domain]  Cd Length: 266  Bit Score: 85.41  E-value: 4.72e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 127 AGIGVGLLCGLTNGFLVTRTGIPPFIATLGMMVSARGLAQYYTQGNPIS----------FLSDSFTAIGQGAMPVIIFFV 196
Cdd:cd06574   52 AAILAGAAAGLVTGFLHTRLKINGLLAGILIMIGLYSINLRIMGGPNIPlgtrdtllglLLLFGISGTLSIPVVLLLIVL 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 197 IAAVFHIALKHTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVVLAARVSSGQSSMGMSYELDAIAAA 276
Cdd:cd06574  132 LVLFLVIWFLRTKLGLAMRATGDNPDMARSLGINVDRTRILGLVISNALAALGGALYAQYQGFADVNMGIGTGVIGLAAV 211

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 490254990 277 VIGGSSL--MGGVGRITGTLIGAMILGLIKSGFTFVGVDAYVQDIIKGIIIVAAV 329
Cdd:cd06574  212 IIGGAIVgrRTIKASILGVIIGAILYRIALALALGSGLIPSDLKLITAGVIVLVL 266
LivH COG0559
Branched-chain amino acid ABC-type transport system, permease component [Amino acid transport ...
 113-326 1.69e-15

Branched-chain amino acid ABC-type transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440325 [Multi-domain]  Cd Length: 290  Bit Score: 75.48  E-value: 1.69e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 113 FPALVNLPAVIPICAGIGVgLLCGLTNGFLVTRTGIPPFIATLGMMVSARGLAQYYTQGNPISF---LSDSFTaIGQGAM 189
Cdd:COG0559   59 LPLWLALLLAVLVAALLGV-LLERLVIRPLRGAPPLALLLATIGLSLVLQGLVLLIFGADPRSFpalLSGSVE-LGGVSI 136

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 190 PVIIFFVIA------AVFHIALKHTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVVLAArVSSGQSS 263
Cdd:COG0559  137 PAYRLFIIVvalvllAALWLFLRRTRLGLAMRAVAQNREAARLMGINVDRVIALTFALGAALAGLAGVLLAP-IYSVSPT 215

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490254990 264 MGMSYELDAIAAAVIggsslmGGVGRITGTLIGAMILGLIKSGFTFVGVDAYVQDIIKGIIIV 326
Cdd:COG0559  216 MGFLLGLKAFAAVVL------GGLGSIPGAVVGGLLLGLAESLGAAYLPSGYKDVVAFVLLIL 272
TM_PBP1_transp_TpRbsC_like cd06580
Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. ...
 108-328 4.98e-15

Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters, which are mainly involved in the uptake of branched-chain amino acids (AAs) or in the uptake of monosaccharides including ribose, galactose, and arabinose, and which generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction.


Pssm-ID: 119322 [Multi-domain]  Cd Length: 234  Bit Score: 73.24  E-value: 4.98e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 108 SLSPMFPALVNLPAVIpiCAGIGVGLLCGLTNGFLVTRTGIPPFIATLGMMVSARGLAQYYtqgnpisflsdsftaigqg 187
Cdd:cd06580   39 ALYLGLPATGSLPLGL--LAAALAGALWALLPALLKAKLGVNEVISGLMLNYIALGLTSYL------------------- 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 188 ampVIIFFVIAAVFHIALKHTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVVLAARVSSGQSSMGMS 267
Cdd:cd06580   98 ---LLLALLLVILVWLLLYRTRFGLRLRAVGENPRAARYAGINVKRVRLLAMLISGALAGLAGAYLVLGVQGRFTEGMSA 174

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490254990 268 -YELDAIAAAVIGGsslmggvGRITGTLIGAMILGLIKSGF----TFVGVDAYVQDIIKGIIIVAA 328
Cdd:cd06580  175 gYGFIAIAVALLGR-------WNPLGILLAALLFGALEAGGialqRSGGVPSELVQVLPGIIVLFV 233
TM_PBP1_LivH_like cd06582
Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two ...
 114-326 9.69e-14

Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivH forms a heterodimer with another TM, LivM, to generate the transmembrane pore. LivM is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.


Pssm-ID: 119324 [Multi-domain]  Cd Length: 272  Bit Score: 70.15  E-value: 9.69e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 114 PALVNLPAVIPICAGIGVGLLCGLTNgFLVTRTGIPPFIATLGMMVSARGLAQYY--TQGNPISFLSDSFTAIG------ 185
Cdd:cd06582   50 PFWLALLLALLVAALLGVLLERLVLR-PLRGAPLLTLLITFGGLLILLQGLLLIFggDPRVPPPPLLSGSVELGgvtipp 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 186 QGAMPVIIFFVIAAVFHIALKHTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVVLAArVSSGQSSMG 265
Cdd:cd06582  129 YRLFIIAVALVLLAALYLFLRRTRLGRAIRAVAQNPEAARLLGINVRRVFALTFALGAALAGLAGVLLAP-ITGVSPTMG 207

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490254990 266 MSYELDAIAAAVIggsslmGGVGRITGTLIGAMILGLIKSGFTFVGVDAYVQDIIKGIIIV 326
Cdd:cd06582  208 LLLLLKAFAAVVL------GGLGSIPGAVVGGLLLGLAESLAAAYLSSGYKDAVAFVLLIL 262
TM_PBP1_LivM_like cd06581
Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two ...
 119-329 2.52e-13

Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivM forms a heterodimer with another TM, LivH, to generate the transmembrane pore. LivH is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.


Pssm-ID: 119323 [Multi-domain]  Cd Length: 268  Bit Score: 69.01  E-value: 2.52e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 119 LPAVIPICAGIGVGLLCGLTNGFLVTRTGIPPF-IATLGMMVSARGLAQY---YTQGN-------PISFLSDSFTAIGQG 187
Cdd:cd06581   45 LPFWLALLAAGLVAALVGLLLGLPALRLRGVYFaIATLAFAEIVRLLALNwssLTGGSnglsgipPPLLGGLLLSSPLAF 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 188 AMPVIIFFVIAAVFHIALKHTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVVLAARVSSGQSSMGMS 267
Cdd:cd06581  125 YYLVLAVLLLVLLLLRRLVRSPFGRALRAIRENEVAAEALGINVTRYKLLAFALSAALAGLAGALYAHYLGFVSPESFGF 204

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490254990 268 YELDAIAAAVIggsslMGGVGRITGTLIGAMILGLIKSGFTFVGvdAYVQDIIKGIIIVAAV 329
Cdd:cd06581  205 ALSIELLLMVV-----LGGLGSLLGPVLGAALLVLLPELLRSLG--PGLRLLVFGLLLILVV 259
LivM COG4177
ABC-type branched-chain amino acid transport system, permease component [Amino acid transport ...
 118-329 1.59e-12

ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443336 [Multi-domain]  Cd Length: 285  Bit Score: 67.03  E-value: 1.59e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 118 NLPAVIPICAGIGVGLLCGLTNGFLVTRTGIPPF-IATLGMMVSARGLA---QYYTQGN-------PISFLSDSFTAIGQ 186
Cdd:COG4177   54 GLPFWLALLLAGLVAALLGLLIGLPALRLRGDYLaIATLAFAEIVRLLAlnlESLTGGAdglsgipRPTLFGLDLGSPLA 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 187 GAMPVIIFFVIAAVFHIALKHTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVVLAARVSSGQ-SSMG 265
Cdd:COG4177  134 FYYLVLALLVLVLLLLRRLVRSRFGRALRAIRENEIAAEALGINVTRYKLLAFVLSAALAGLAGALYAHYVGFVSpESFS 213

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490254990 266 MSYELDAIAAAVIggsslmGGVGRITGTLIGAMILGLIKSGFTFVgvdAYVQDIIKGIIIVAAV 329
Cdd:COG4177  214 FLLSIEILLMVVL------GGLGSLLGPVLGAVLLVLLPELLRSL---PEYRLLIFGLLLILVV 268
NupP COG4603
ABC-type guanosine uptake system NupNOPQ, permease component NupP [Nucleotide transport and ...
 111-333 6.11e-11

ABC-type guanosine uptake system NupNOPQ, permease component NupP [Nucleotide transport and metabolism];


Pssm-ID: 443653 [Multi-domain]  Cd Length: 356  Bit Score: 62.83  E-value: 6.11e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 111 PMFPALVNLPAVIpiCAGIGVGLLCGLTNGFLVTRTGIPPFIATLgMMVS-ARGLAQYYTQG---NPISFLSDSfTAIGQ 186
Cdd:COG4603  108 PGLPGPLHLPLAL--LAGALAGALWAAIPGLLKARFGVNEVITTL-MLNYiALYLVNYLVRGplrDPGSGFPQT-PPIPE 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 187 GAM------------PVIIFFVIAAVFHIALKHTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVV-L 253
Cdd:COG4603  184 SARlprllpgtrlhlGLLIALLAAVLVWVLLNRTTLGYELRAVGLNPRAARYAGINVKRLIVLAMLISGALAGLAGAVeV 263

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 254 AARVSSGQSSMGMSYELDAIAAAVIGGSSlmggvgrITGTLIGAMILGLIKSGF----TFVGVDAYVQDIIKGIIIVAAV 329
Cdd:COG4603  264 LGVQGRLTPGFSPGYGFTGIAVALLGRNN-------PLGIILAALLFGALYVGGdamqRALGVPSEIVDVIQGLIILFVL 336


                 ....
gi 490254990 330 TIDM 333
Cdd:COG4603  337 AADF 340
NupQ COG1079
ABC-type guanosine uptake system NupNOPQ, permease subunit NupQ [Nucleotide transport and ...
 125-254 8.08e-06

ABC-type guanosine uptake system NupNOPQ, permease subunit NupQ [Nucleotide transport and metabolism];


Pssm-ID: 440697 [Multi-domain]  Cd Length: 309  Bit Score: 46.99  E-value: 8.08e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 125 ICAGIGVGLLCGLTNGFLVTRTGIPPFIATLGMMVSARGLAQY----YTQGNPISFLSDSFTAI---GQGAMPVI--IFF 195
Cdd:COG1079   66 LLAAALAGALLALLHAFLTITLRANQIVSGLALNLLALGLTAFlgrlLFGQGGQTPSIPGLPPIpipGLSDIPVLgpLLF 145

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490254990 196 ----------VIAAVFHIALKHTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVVLA 254
Cdd:COG1079  146 gqsplvylalLLVPLVWWVLYRTRFGLRLRAVGENPAAADALGINVYRIRYLAVLIGGALAGLGGAYLS 214
PRK10740 PRK10740
high-affinity branched-chain amino acid ABC transporter permease LivH;
192-302 1.97e-04

high-affinity branched-chain amino acid ABC transporter permease LivH;


Pssm-ID: 182689 [Multi-domain]  Cd Length: 308  Bit Score: 42.60  E-value: 1.97e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 192 IIFFVIAAVFHIALKHTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVVLAARVSSGQSSMGMSYELD 271
Cdd:PRK10740 162 IVTFLAMLALTIFIRYSRMGRACRACAEDLKMASLLGINTDRVIALTFVIGAAMAAVAGVLLGQFYGVINPYIGFMAGMK 241

                         90       100       110
                 ....*....|....*....|....*....|.
gi 490254990 272 AIAAAViggsslMGGVGRITGTLIGAMILGL 302
Cdd:PRK10740 242 AFTAAV------LGGIGSIPGAMIGGLILGI 266
COG4120 COG4120
ABC-type uncharacterized transport system, permease component [General function prediction ...
 125-254 1.32e-03

ABC-type uncharacterized transport system, permease component [General function prediction only];


Pssm-ID: 443296  Cd Length: 296  Bit Score: 40.10  E-value: 1.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 125 ICAGIGVGLLCGLTNGFLVTRTGIPPFIATLGMMVSARGLAQYYTQGNPISFLSD-------SFTAIGQGAMPVIIFFVI 197
Cdd:COG4120   62 TLAAFLAGALAGLVTGLLHTKLKIPPLLAGILTMTALYSINLRIMGKPNIPLLGEdtiftllPDLGLPGDWAKLLVLLVI 141

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254990 198 AAVFHIALK---HTRYGKYVYAIGGNMTSAKVSGINVNKYLVIVYTIAGALSGLAGVVLA 254
Cdd:COG4120  142 VLVIKLLLDwflKTELGLALRATGDNPQMARALGINTDRMKILGLALSNGLVALSGALVA 201
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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