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Conserved domains on  [gi|490246431|ref|WP_004144603|]
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MULTISPECIES: taurine ABC transporter permease TauC [Klebsiella]

Protein Classification

taurine ABC transporter permease TauC( domain architecture ID 10793353)

taurine ABC transporter permease TauC is part of a binding-protein-dependent transport system for taurine

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10160 PRK10160
taurine ABC transporter permease TauC;
1-275 2.73e-162

taurine ABC transporter permease TauC;


:

Pssm-ID: 182276  Cd Length: 275  Bit Score: 451.16  E-value: 2.73e-162
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431   1 MSVVLNDKPRQSTLKWRWPLSRQLTLSVATLAVLLAVWWAVAALQLISPLFLPPPGQVLQKLITIAGPQGFMDATLWQHL 80
Cdd:PRK10160   1 MSVLINEKLHSRRLKWRWPLSRQLTLSIGTLAVLLAVWWAVAALQLISPLFLPPPQQVLAKLLTIAGPQGFMDATLWQHL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431  81 AASLTRIVIALLAAVLIGVPVGIAMGLNSTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS 160
Cdd:PRK10160  81 AASLTRIVLALLAAVVIGIPVGIAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431 161 ALAGVKSAQQVRIRAARSLGASRAQVLWLVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD 240
Cdd:PRK10160 161 ALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD 240

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 490246431 241 VVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ 275
Cdd:PRK10160 241 VVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ 275
 
Name Accession Description Interval E-value
PRK10160 PRK10160
taurine ABC transporter permease TauC;
1-275 2.73e-162

taurine ABC transporter permease TauC;


Pssm-ID: 182276  Cd Length: 275  Bit Score: 451.16  E-value: 2.73e-162
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431   1 MSVVLNDKPRQSTLKWRWPLSRQLTLSVATLAVLLAVWWAVAALQLISPLFLPPPGQVLQKLITIAGPQGFMDATLWQHL 80
Cdd:PRK10160   1 MSVLINEKLHSRRLKWRWPLSRQLTLSIGTLAVLLAVWWAVAALQLISPLFLPPPQQVLAKLLTIAGPQGFMDATLWQHL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431  81 AASLTRIVIALLAAVLIGVPVGIAMGLNSTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS 160
Cdd:PRK10160  81 AASLTRIVLALLAAVVIGIPVGIAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431 161 ALAGVKSAQQVRIRAARSLGASRAQVLWLVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD 240
Cdd:PRK10160 161 ALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD 240

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 490246431 241 VVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ 275
Cdd:PRK10160 241 VVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ 275
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 22-271 1.31e-71

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 220.40  E-value: 1.31e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431  22 RQLTLSVATLAVLLAVWWAVAALQLISPLFLPPPGQVLQKLITIAGpqgfmDATLWQHLAASLTRIVIALLAAVLIGVPV 101
Cdd:COG0600   10 RRLLLPLLSLALLLALWELAARLGLVPPFLLPSPSAVLAALVELLA-----SGELWEHLLASLLRVLLGFALAALLGVPL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431 102 GIAMGLNSTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMSALAGVKSAQQVRIRAARSLGA 181
Cdd:COG0600   85 GLLLGLSRLLRRLLDPLLVFLRPIPPLALAPLLILWFGIGEASKIFVIFLGAFFPILLNTAAGVRSVDPELLELARSLGA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431 182 SRAQVLWLVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDVVLAGIAVIAIIAFLLELGLR 261
Cdd:COG0600  165 SRWQILRKVVLPAALPYIFTGLRIALGLAWIGLVVAELLGASSGLGYLILDARQLLDTDLVFAAILVIGLLGLLLDLLLR 244

                        250
                 ....*....|
gi 490246431 262 ALQRRLTPWH 271
Cdd:COG0600  245 LLERRLLRWR 254
ntrB TIGR01183
nitrate ABC transporter, permease protein; This model describes the nitrate transport permease ...
 70-233 7.56e-25

nitrate ABC transporter, permease protein; This model describes the nitrate transport permease in bacteria. This is gene product of ntrB. The nitrate transport permease is the integral membrane component of the nitrate transport system and belongs to the ATP-binding cassette (ABC) superfamily. At least in photosynthetic bacteria nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA, ntrB, ntrC, ntrD, narB. Functionally ntrC and ntrD resemble the ATP binding components of the binding protein-dependent transport systems. Mutational studies have shown that ntrB and ntrC are mandatory for nitrate accumulation. Nitrate reductase is encoded by narB. [Transport and binding proteins, Anions]


Pssm-ID: 130251  Cd Length: 202  Bit Score: 98.33  E-value: 7.56e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431   70 GFMDATLWQHLAASLTRIVIALLAAVLIGVPVGIAMGLNSTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLI 149
Cdd:TIGR01183   9 GGTDKGLFWQIIASLTRVAVGFSIAAIIGIAVGILIGLSKFLNAALDPIFQVLRTIPPLAWLPIALAAFQDAQPAAIFVI 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431  150 YLAIFAPVAMSALAGVKSAQQVRIRAARSLGASRAQVLWLVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFM 229
Cdd:TIGR01183  89 FITAIWPIIINTAVGVQQIPQDYNNVARVLKLSKSDYFLKVLLPAAVPYIFTGLRIAIGLSWLAIVAAEMLMGGVGIGFF 168


                  ....
gi 490246431  230 VQSA 233
Cdd:TIGR01183 169 IWDA 172
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 98-269 3.23e-13

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 66.17  E-value: 3.23e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431   98 GVPVGI--AMGLNSTVRGILDPLIELYRPVPPLAYLPLMVI-----WFGIGETSKILLIYLAIFAPVAMSALAGVKSAQQ 170
Cdd:pfam00528   1 GIPLGIiaALRRGRRLDRLLRPLIDLLQALPSFVLAILLVViailsILGHGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431  171 VRIRAARSLGASRAQVLWLVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDVVLAGIAVIA 250
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAA 160

                         170
                  ....*....|....*....
gi 490246431  251 IIAFLLELGLRALQRRLTP 269
Cdd:pfam00528 161 LILLLLNLLVDILQRLLDP 179
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 80-222 9.98e-11

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 59.60  E-value: 9.98e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431  80 LAASLTRIVIALLAAVLIGVPVGIAMGLN-STVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSK---------ILLI 149
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKrGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGilpglglpaLILA 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490246431 150 YLAIFAPVAMSALAGVKSAQQVRIRAARSLGASRAQVLWLVILPGALPEILTGLRIGLGVGWSTLVAAELIAA 222
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG 153
 
Name Accession Description Interval E-value
PRK10160 PRK10160
taurine ABC transporter permease TauC;
1-275 2.73e-162

taurine ABC transporter permease TauC;


Pssm-ID: 182276  Cd Length: 275  Bit Score: 451.16  E-value: 2.73e-162
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431   1 MSVVLNDKPRQSTLKWRWPLSRQLTLSVATLAVLLAVWWAVAALQLISPLFLPPPGQVLQKLITIAGPQGFMDATLWQHL 80
Cdd:PRK10160   1 MSVLINEKLHSRRLKWRWPLSRQLTLSIGTLAVLLAVWWAVAALQLISPLFLPPPQQVLAKLLTIAGPQGFMDATLWQHL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431  81 AASLTRIVIALLAAVLIGVPVGIAMGLNSTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS 160
Cdd:PRK10160  81 AASLTRIVLALLAAVVIGIPVGIAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431 161 ALAGVKSAQQVRIRAARSLGASRAQVLWLVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD 240
Cdd:PRK10160 161 ALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD 240

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 490246431 241 VVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ 275
Cdd:PRK10160 241 VVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ 275
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 22-271 1.31e-71

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 220.40  E-value: 1.31e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431  22 RQLTLSVATLAVLLAVWWAVAALQLISPLFLPPPGQVLQKLITIAGpqgfmDATLWQHLAASLTRIVIALLAAVLIGVPV 101
Cdd:COG0600   10 RRLLLPLLSLALLLALWELAARLGLVPPFLLPSPSAVLAALVELLA-----SGELWEHLLASLLRVLLGFALAALLGVPL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431 102 GIAMGLNSTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMSALAGVKSAQQVRIRAARSLGA 181
Cdd:COG0600   85 GLLLGLSRLLRRLLDPLLVFLRPIPPLALAPLLILWFGIGEASKIFVIFLGAFFPILLNTAAGVRSVDPELLELARSLGA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431 182 SRAQVLWLVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDVVLAGIAVIAIIAFLLELGLR 261
Cdd:COG0600  165 SRWQILRKVVLPAALPYIFTGLRIALGLAWIGLVVAELLGASSGLGYLILDARQLLDTDLVFAAILVIGLLGLLLDLLLR 244

                        250
                 ....*....|
gi 490246431 262 ALQRRLTPWH 271
Cdd:COG0600  245 LLERRLLRWR 254
ssuC PRK11365
aliphatic sulfonate ABC transporter permease SsuC;
34-271 8.04e-37

aliphatic sulfonate ABC transporter permease SsuC;


Pssm-ID: 183100  Cd Length: 263  Bit Score: 131.21  E-value: 8.04e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431  34 LLAVWWAVAALQLISPLFLPPPGQVLQKLITIAGpqgfmDATLWQHLAASLTRIVIALLAAVLIGVPVGIAMGLNSTVRG 113
Cdd:PRK11365  21 IVAVWQLASSVGWLSTRILPSPEGVVTAFWTLSA-----SGELWQHLAISSWRALIGFSIGGSLGLILGLISGLSRWGER 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431 114 ILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMSALAGVKSAQQVRIRAARSLGASRAQVLWLVILP 193
Cdd:PRK11365  96 LLDTSIQMLRNVPHLALIPLVILWFGIDESAKIFLVALGTLFPIYINTWHGIRNIDRGLVEMARSYGLSGIPLFIHVILP 175

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490246431 194 GALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDVVLAGIAVIAIIAFLLELGLRALQRRLTPWH 271
Cdd:PRK11365 176 GALPSIMVGVRFALGLMWLTLIVAETISANSGIGYLAMNAREFLQTDVVVVAIILYALLGKLADVSAQLLERLWLRWN 253
ntrB TIGR01183
nitrate ABC transporter, permease protein; This model describes the nitrate transport permease ...
 70-233 7.56e-25

nitrate ABC transporter, permease protein; This model describes the nitrate transport permease in bacteria. This is gene product of ntrB. The nitrate transport permease is the integral membrane component of the nitrate transport system and belongs to the ATP-binding cassette (ABC) superfamily. At least in photosynthetic bacteria nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA, ntrB, ntrC, ntrD, narB. Functionally ntrC and ntrD resemble the ATP binding components of the binding protein-dependent transport systems. Mutational studies have shown that ntrB and ntrC are mandatory for nitrate accumulation. Nitrate reductase is encoded by narB. [Transport and binding proteins, Anions]


Pssm-ID: 130251  Cd Length: 202  Bit Score: 98.33  E-value: 7.56e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431   70 GFMDATLWQHLAASLTRIVIALLAAVLIGVPVGIAMGLNSTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLI 149
Cdd:TIGR01183   9 GGTDKGLFWQIIASLTRVAVGFSIAAIIGIAVGILIGLSKFLNAALDPIFQVLRTIPPLAWLPIALAAFQDAQPAAIFVI 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431  150 YLAIFAPVAMSALAGVKSAQQVRIRAARSLGASRAQVLWLVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFM 229
Cdd:TIGR01183  89 FITAIWPIIINTAVGVQQIPQDYNNVARVLKLSKSDYFLKVLLPAAVPYIFTGLRIAIGLSWLAIVAAEMLMGGVGIGFF 168


                  ....
gi 490246431  230 VQSA 233
Cdd:TIGR01183 169 IWDA 172
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 76-270 2.08e-18

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 81.25  E-value: 2.08e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431  76 LWQHLAASLtrivIALLAAVLIGVPVGIAMGLNSTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFA 155
Cdd:COG1174   20 LLEHLLLVL----LALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGIGPAPAIIALVLYALL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431 156 PVAMSALAGVKSAQQVRIRAARSLGASRAQVLWLVILPGALPEILTGLRIGL--GVGWSTLVAaeLIAAtRGLGFMVQSA 233
Cdd:COG1174   96 PILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAvqNIGTATLAA--LIGA-GGLGDLIFDG 172

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 490246431 234 GEFLATDVVLAGIAVIAIIAFLLELGLRALQRRLTPW 270
Cdd:COG1174  173 LQLNNTALILAGAILVALLALLVDLLLALLERLLTPR 209
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 98-269 3.23e-13

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 66.17  E-value: 3.23e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431   98 GVPVGI--AMGLNSTVRGILDPLIELYRPVPPLAYLPLMVI-----WFGIGETSKILLIYLAIFAPVAMSALAGVKSAQQ 170
Cdd:pfam00528   1 GIPLGIiaALRRGRRLDRLLRPLIDLLQALPSFVLAILLVViailsILGHGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431  171 VRIRAARSLGASRAQVLWLVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDVVLAGIAVIA 250
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAA 160

                         170
                  ....*....|....*....
gi 490246431  251 IIAFLLELGLRALQRRLTP 269
Cdd:pfam00528 161 LILLLLNLLVDILQRLLDP 179
PRK10952 PRK10952
proline/glycine betaine ABC transporter permease ProW;
77-230 4.16e-12

proline/glycine betaine ABC transporter permease ProW;


Pssm-ID: 236805  Cd Length: 355  Bit Score: 65.50  E-value: 4.16e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431  77 WQHLAASLTRIVIALLAAVLIGVPVGIAMGLNSTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAP 156
Cdd:PRK10952 143 WSQAMVTLALVLTALLFCIVIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPP 222

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490246431 157 VAMSALAGVKSAQQVRIRAARSLGASRAQVLWLVILPGALPEILTGLRIGLGVGWSTLVAAELIAATrGLGFMV 230
Cdd:PRK10952 223 IVRLTILGINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVG-GLGQMV 295
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 80-222 9.98e-11

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 59.60  E-value: 9.98e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431  80 LAASLTRIVIALLAAVLIGVPVGIAMGLN-STVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSK---------ILLI 149
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKrGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGilpglglpaLILA 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490246431 150 YLAIFAPVAMSALAGVKSAQQVRIRAARSLGASRAQVLWLVILPGALPEILTGLRIGLGVGWSTLVAAELIAA 222
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG 153
COG4986 COG4986
ABC-type anion transport system, duplicated permease component [Inorganic ion transport and ...
 8-227 2.30e-06

ABC-type anion transport system, duplicated permease component [Inorganic ion transport and metabolism];


Pssm-ID: 444010 [Multi-domain]  Cd Length: 576  Bit Score: 48.30  E-value: 2.30e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431   8 KPRQSTLKWRWPLSRQLTLSVATLAVLLAVWWAVAALQLIspLFLPPPGQVLQklITIAGpqgfmdatlwqhlAASLTRI 87
Cdd:COG4986  316 PRAPRPPAVSRALSRWLDRLWLALLALLVLYGLWRLLLFL--LTEVGLSEVLH--VFLLG-------------LLTLLRV 378

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431  88 VIALLAAVLIGVPVGIAMGLNSTVRGILDPLIELYRPVPPLAYLPLMVIWF-GIGETSKILLIYLAIFAP---VAMSALA 163
Cdd:COG4986  379 VVLIALASLIWVPVGVWIGLRPRLARRLQPVAQFLASFPANLLFPVAVLLIvRFGLNPNIWLSPLMILGTqwyILFNVIA 458

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431 164 GVKSAQQVRIRAARSLGASRAQVLWLVILPGALPEILTGLRIGLGVGWSTLVAAELIA------ATRGLG 227
Cdd:COG4986  459 GASAIPNDLREAARNFGLRGWLWWRRLILPGIFPYYVTGAITASGGAWNASIVAEYVSwgdttlQATGLG 528
MetP COG2011
ABC-type methionine transport system, permease component [Amino acid transport and metabolism]; ...
 72-203 5.48e-06

ABC-type methionine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 441614  Cd Length: 220  Bit Score: 46.20  E-value: 5.48e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431  72 MDATLWQHLAASLTRIVIALLAAVLIGVPVGIAM------GL--NSTVRGILDPLIELYRPVPplaYLPLMVIWF----- 138
Cdd:COG2011    8 LWPLLLQATGETLYMVGVSTLIAVLLGLPLGVLLvltrpgGLlpNPVLYRVLGVIVNIFRSIP---FIILLVALIpltrl 84

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490246431 139 ----GIGETSKIL-LIYLAI--FAPVAMSALAGVKSAqqvRIRAARSLGASRAQVLWLVILPGALPEILTGL 203
Cdd:COG2011   85 ivgtSIGTTAAIVpLTIAAIpfFARLVENALREVDPG---VIEAAQAMGASPWQIIFKVLLPEALPSLILGL 153
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 71-202 5.38e-05

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 43.56  E-value: 5.38e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431  71 FMDATLWQHLAASLTRIVIALLAAVLIGVPVGIAMG-LNSTVRGILDPLIELYRPVPPLAY-LPLMVIWFGIGETSKILL 148
Cdd:COG1177   54 FSDPRLLDALLNSLLIALLSTLLATVLGTPAALALArYRFRGRRLLLALLLLPLVVPGIVLgVALLLLFSALGLSGGLWG 133

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 490246431 149 IYLAIFAP----VAMSALAGVKSAQQVRIRAARSLGASRAQVLWLVILPGALPEILTG 202
Cdd:COG1177  134 LILAHVVFtlpfVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAG 191
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 76-200 2.58e-04

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 41.21  E-value: 2.58e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431  76 LWQHLAASLTRIVIALLAAVLIGVPVGIAMGLNSTV-RGILDPLIELYRPVPPLayLPLMVIWFGIGEtskiLLIYLAIF 154
Cdd:COG0765   15 LLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVlRWLATAYVEFFRGTPLL--VQLFFIYFGLPL----LGIDLSPF 88

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 490246431 155 --APVAMSALAGVKSAQQVR----------IRAARSLGASRAQVLWLVILPGALPEIL 200
Cdd:COG0765   89 vaAVIALTLNSAAYLAEIVRagiqsvpkgqWEAARALGLSRWQTMRRIILPQALRIIL 146
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
71-203 3.78e-04

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 41.69  E-value: 3.78e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431  71 FMDATLWQHLAASLTRIVIALLAAVLIGVPVGIAMG-LNSTVRGILDPLIELYRPVPP----LAYLPLMVIWFGIGETSK 145
Cdd:COG1178  331 LLDPSLLRALLNSLLLALLAALLAVLLALLLAYLVRrRRGRLARLLDRLAMLPYAVPGivlgLGLLLLFNRPLPLLLYGT 410

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490246431 146 ILLI---YLAIFAPVAM-SALAGVKSAQQVRIRAARSLGASRAQVLWLVILPGALPEILTGL 203
Cdd:COG1178  411 LAILvlaYVVRFLPFALrSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAA 472
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 76-200 6.84e-04

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 40.22  E-value: 6.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431   76 LWQHLAASLTRIVIALLAAVLIGVPVGIAMGLNSTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFA 155
Cdd:TIGR01097  60 LLETLAMAILGTVLAAVLAVPLALLAARNITPSPWLYGLARLLLNFLRAIPELVWALIFVAAVGLGPFAGVLALAFHTVG 139

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 490246431  156 PVAMSALAGVKSAQQVRIRAARSLGASRAQVLWLVILPGALPEIL 200
Cdd:TIGR01097 140 FLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQVLPQFL 184
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 175-203 7.23e-04

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 40.12  E-value: 7.23e-04
                         10        20
                 ....*....|....*....|....*....
gi 490246431 175 AARSLGASRAQVLWLVILPGALPEILTGL 203
Cdd:COG0555  169 AAATLGASRWQTFRRVILPLLLPALLTGF 197
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
 28-200 1.53e-03

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 38.91  E-value: 1.53e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431  28 VATLAVLLAVWWAVAALQlISPLFLPPPGQVLQKLITIAGPQGFmdATLWQHLAASLTRIVIALLA---AVLIGVPVGIA 104
Cdd:COG3639    1 LLLLALLALLVWSLWGLE-FDLGRLIDGLPNLADFLSRFFPPDW--SYLPDLLSALLETLAIALLGtllGAVLALPLAFL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431 105 ----MGLNSTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVA--MS-ALAGVKSAQqvrIRAAR 177
Cdd:COG3639   78 aarnLAPNPWVRLLARRLLNVLRAIPELVWALIFVAAVGLGPFAGVLALAIHTIGFLGklFAeAIEEIDPGP---VEALR 154

                        170       180
                 ....*....|....*....|...
gi 490246431 178 SLGASRAQVLWLVILPGALPEIL 200
Cdd:COG3639  155 ATGASRLQVIRYGVLPQVLPQFL 177
PstA COG0581
ABC-type phosphate transport system, permease component [Inorganic ion transport and ...
 175-208 2.36e-03

ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440346 [Multi-domain]  Cd Length: 259  Bit Score: 38.48  E-value: 2.36e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 490246431 175 AARSLGASRAQVLWLVILPGALPEILTGLRIGLG 208
Cdd:COG0581  147 ASYALGATKWQTIRKVVLPAALPGILTGVILAIA 180
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 173-202 6.78e-03

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 37.43  E-value: 6.78e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 490246431 173 IRAARSLGASRAQVLWLVILPGALPEILTG 202
Cdd:COG1176  185 LEAARDLGASPWQTFRRVILPLSLPGIIAG 214
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 76-233 9.18e-03

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 36.97  E-value: 9.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431  76 LWQHLAASLTRIVIALLAAVLIGVPVGIAMGL--NSTVRGILDPLIELYRPVPPLAYLPLMVIWFGI--------GETSK 145
Cdd:COG0601   91 IAERLPVTLELALLALLLALLIGIPLGILAALrrGSWLDRLITVLALLGISIPSFWLGLLLILLFAVklgwlpvsGRVSP 170

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490246431 146 -----------------ILLIYLAIFAPVAMSALAGVKSAQQVriRAARSLGASRAQVLWLVILPGALPEILT--GLRIG 206
Cdd:COG0601  171 wedfldalrhlilpaltLALGSLAGIARLTRSSMLEVLGQDYV--RTARAKGLSERRVLLRHALRNALIPVVTvlGLQLG 248

                        170       180
                 ....*....|....*....|....*..
gi 490246431 207 LGVGWSTLVaaELIAATRGLGFMVQSA 233
Cdd:COG0601  249 GLLGGAVVV--ETVFSWPGLGRLLVDA 273
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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