|
Name |
Accession |
Description |
Interval |
E-value |
| propeller_TolB |
TIGR02800 |
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB ... |
13-427 |
0e+00 |
|
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB periplasmic protein of Gram-negative bacteria. TolB is part of the Tol-Pal (peptidoglycan-associated lipoprotein) multiprotein complex, comprising five envelope proteins, TolQ, TolR, TolA, TolB and Pal, which form two complexes. The TolQ, TolR and TolA inner-membrane proteins interact via their transmembrane domains. The {beta}-propeller domain of the periplasmic protein TolB is responsible for its interaction with Pal. TolB also interacts with the outer-membrane peptidoglycan-associated proteins Lpp and OmpA. TolA undergoes a conformational change in response to changes in the proton-motive force, and interacts with Pal in an energy-dependent manner. The C-terminal periplasmic domain of TolA also interacts with the N-terminal domain of TolB. The Tol-PAL system is required for bacterial outer membrane integrity. E. coli TolB is involved in the tonB-independent uptake of group A colicins (colicins A, E1, E2, E3 and K), and is necessary for the colicins to reach their respective targets after initial binding to the bacteria. It is also involved in uptake of filamentous DNA. Study of its structure suggest that the TolB protein might be involved in the recycling of peptidoglycan or in its covalent linking with lipoproteins. The Tol-Pal system is also implicated in pathogenesis of E. coli, Haemophilus ducreyi , Salmonella enterica and Vibrio cholerae, but the mechanism(s) is unclear. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274305 [Multi-domain] Cd Length: 417 Bit Score: 539.55 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 13 MLWAAVLHAEVRIEITQGVDSARPIGVVPFQWAGQGAAP----EDVGGIVAADLRNSGKFNPLDRSRLPQQPGSAQEVQP 88
Cdd:TIGR02800 1 LAVSTPAAADLTIEITKGGASALPIAVAPFSNDGGGSPDanlgESIAEVIANDLKRSGLFSPVDKAGLPSNPIAESQVNP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 89 AAWSALGIDAVVVGQVTQNPDGSYNVAYQLVDTGGApGTVLAQNSFKVTKQYLRYAAHAASDAVFEKLTGIKGAFRTRIA 168
Cdd:TIGR02800 81 AAWQALGADALVVGSVTPNGNGRYTVRFRLYDVVSG-QLQLLGKQYTVTASQLRRVAHRIADAIYEKLTGERGAFSTRIA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 169 YVVQtNGGQFPYELRVSDYDGYNQFLVHRSTQPLMSPAWSPDGAKLAYVTFESGRSALVVQTLANGSVRQIASFPQHNGA 248
Cdd:TIGR02800 160 YVSK-SGKSRRYELQVADYDGANPQTITRSREPILSPAWSPDGQKLAYVSFESGKPEIYVQDLATGQREKVASFPGMNGA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 249 PAFSPDGSKLAFALSKTGSLNLYVMDLGSGQIRQVTNGRSNNTEPSWFPDSQNLAFTSDQAGRPQVYKVNINGGTPQRIT 328
Cdd:TIGR02800 239 PAFSPDGSKLAVSLSKDGNPDIYVMDLDGKQLTRLTNGPGIDTEPSWSPDGKSIAFTSDRGGSPQIYMMDADGGEVRRLT 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 329 WEGSQNQDADVSADGKTMVMVSSAGGQQHIAKQDLEAGGVQVLSSTFLDETPSLAPNGTMVIYSSSQGMGSVLNLVSTDG 408
Cdd:TIGR02800 319 FRGGYNASPSWSPDGDLIAFVHREGGGFNIAVMDLDGGGERVLTDTGLDESPSFAPNGRMILYATTRGGRGVLGLVSTDG 398
|
410
....*....|....*....
gi 490232244 409 RFKARLPATDGQVKSPAWS 427
Cdd:TIGR02800 399 RFRARLPLGNGDVREPAWS 417
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
258-416 |
8.76e-49 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 163.30 E-value: 8.76e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 258 LAFALSKTGSLNLYVMDLGSGQIRQVTNGRSNNTEPSWFPDSQNLAFTSDQAGRPQVYKVNINGGTPQRITWEGSQNQDA 337
Cdd:COG0823 1 LAFTLSRDGNSDIYVVDLDGGEPRRLTNSPGIDTSPAWSPDGRRIAFTSDRGGGPQIYVVDADGGEPRRLTFGGGYNASP 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490232244 338 DVSADGKTMVMVSSAGGQQHIAKQDLEAGGVQVLSSTFLDetPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRfKARLPA 416
Cdd:COG0823 81 SWSPDGKRLAFVSRSDGRFDIYVLDLDGGAPRRLTDGPGS--PSWSPDGRRIVFSSDRGGRPDLYVVDLDGR-KRRLTP 156
|
|
| TolB_N |
pfam04052 |
TolB amino-terminal domain; TolB is an essential periplasmic component of the tol-dependent ... |
23-121 |
4.61e-41 |
|
TolB amino-terminal domain; TolB is an essential periplasmic component of the tol-dependent translocation system. This function of this amino terminal domain is uncertain.
Pssm-ID: 461148 Cd Length: 105 Bit Score: 141.22 E-value: 4.61e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 23 VRIEITQGVDSARPIGVVPFQWAGQGAAPEDVGGIVAADLRNSGKFNPLDRSRLPQQPGSAQEVQPAAWSALGIDAVVVG 102
Cdd:pfam04052 1 LRIEITGGGDTALPIAVVPFQGEGGADLPQDISEVIAADLERSGLFRPIDPAAFPQRPTSDSEVDFADWRALGADALVTG 80
|
90
....*....|....*....
gi 490232244 103 QVTQNPDGSYNVAYQLVDT 121
Cdd:pfam04052 81 SVTRGGDGRYKVEFRLYDV 99
|
|
| tolB |
PRK01029 |
Tol-Pal system protein TolB; |
131-426 |
2.67e-26 |
|
Tol-Pal system protein TolB;
Pssm-ID: 234889 [Multi-domain] Cd Length: 428 Bit Score: 109.85 E-value: 2.67e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 131 QNSFKVTKQYL-------RYAAHAASDAVFEKLTGIKGAFRTRIAYVVQTNGGQFPY---ELRVSDYDGYNQFLVHRSTQ 200
Cdd:PRK01029 106 KNPQKLFSLELsgdlskdRQKIHEAADTIHYALTGVPGISSGKIIFSLSTTNSDTELkqgELWSVDYDGQNLRPLTQEHS 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 201 PLMSPAWSPDGAKLA--YVTFESGRSALVVQTLANGSVRQIASFPQHNGAPAFSPDGSKLAFALSKTGSLNLYV--MDLG 276
Cdd:PRK01029 186 LSITPTWMHIGSGFPylYVSYKLGVPKIFLGSLENPAGKKILALQGNQLMPTFSPRKKLLAFISDRYGNPDLFIqsFSLE 265
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 277 SGQI---RQVTNGR-SNNTEPSWFPDSQNLAFTSDQAGRPQVYKVNIN--GGTPQRITWEGSQNQDADVSADGKTMVMVS 350
Cdd:PRK01029 266 TGAIgkpRRLLNEAfGTQGNPSFSPDGTRLVFVSNKDGRPRIYIMQIDpeGQSPRLLTKKYRNSSCPAWSPDGKKIAFCS 345
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490232244 351 SAGGQQHIAKQDLEAGGVQVLSSTFLD-ETPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRFKARLPATDGQVKSPAW 426
Cdd:PRK01029 346 VIKGVRQICVYDLATGRDYQLTTSPENkESPSWAIDSLHLVYSAGNSNESELYLISLITKKTRKIVIGSGEKRFPSW 422
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| propeller_TolB |
TIGR02800 |
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB ... |
13-427 |
0e+00 |
|
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB periplasmic protein of Gram-negative bacteria. TolB is part of the Tol-Pal (peptidoglycan-associated lipoprotein) multiprotein complex, comprising five envelope proteins, TolQ, TolR, TolA, TolB and Pal, which form two complexes. The TolQ, TolR and TolA inner-membrane proteins interact via their transmembrane domains. The {beta}-propeller domain of the periplasmic protein TolB is responsible for its interaction with Pal. TolB also interacts with the outer-membrane peptidoglycan-associated proteins Lpp and OmpA. TolA undergoes a conformational change in response to changes in the proton-motive force, and interacts with Pal in an energy-dependent manner. The C-terminal periplasmic domain of TolA also interacts with the N-terminal domain of TolB. The Tol-PAL system is required for bacterial outer membrane integrity. E. coli TolB is involved in the tonB-independent uptake of group A colicins (colicins A, E1, E2, E3 and K), and is necessary for the colicins to reach their respective targets after initial binding to the bacteria. It is also involved in uptake of filamentous DNA. Study of its structure suggest that the TolB protein might be involved in the recycling of peptidoglycan or in its covalent linking with lipoproteins. The Tol-Pal system is also implicated in pathogenesis of E. coli, Haemophilus ducreyi , Salmonella enterica and Vibrio cholerae, but the mechanism(s) is unclear. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274305 [Multi-domain] Cd Length: 417 Bit Score: 539.55 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 13 MLWAAVLHAEVRIEITQGVDSARPIGVVPFQWAGQGAAP----EDVGGIVAADLRNSGKFNPLDRSRLPQQPGSAQEVQP 88
Cdd:TIGR02800 1 LAVSTPAAADLTIEITKGGASALPIAVAPFSNDGGGSPDanlgESIAEVIANDLKRSGLFSPVDKAGLPSNPIAESQVNP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 89 AAWSALGIDAVVVGQVTQNPDGSYNVAYQLVDTGGApGTVLAQNSFKVTKQYLRYAAHAASDAVFEKLTGIKGAFRTRIA 168
Cdd:TIGR02800 81 AAWQALGADALVVGSVTPNGNGRYTVRFRLYDVVSG-QLQLLGKQYTVTASQLRRVAHRIADAIYEKLTGERGAFSTRIA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 169 YVVQtNGGQFPYELRVSDYDGYNQFLVHRSTQPLMSPAWSPDGAKLAYVTFESGRSALVVQTLANGSVRQIASFPQHNGA 248
Cdd:TIGR02800 160 YVSK-SGKSRRYELQVADYDGANPQTITRSREPILSPAWSPDGQKLAYVSFESGKPEIYVQDLATGQREKVASFPGMNGA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 249 PAFSPDGSKLAFALSKTGSLNLYVMDLGSGQIRQVTNGRSNNTEPSWFPDSQNLAFTSDQAGRPQVYKVNINGGTPQRIT 328
Cdd:TIGR02800 239 PAFSPDGSKLAVSLSKDGNPDIYVMDLDGKQLTRLTNGPGIDTEPSWSPDGKSIAFTSDRGGSPQIYMMDADGGEVRRLT 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 329 WEGSQNQDADVSADGKTMVMVSSAGGQQHIAKQDLEAGGVQVLSSTFLDETPSLAPNGTMVIYSSSQGMGSVLNLVSTDG 408
Cdd:TIGR02800 319 FRGGYNASPSWSPDGDLIAFVHREGGGFNIAVMDLDGGGERVLTDTGLDESPSFAPNGRMILYATTRGGRGVLGLVSTDG 398
|
410
....*....|....*....
gi 490232244 409 RFKARLPATDGQVKSPAWS 427
Cdd:TIGR02800 399 RFRARLPLGNGDVREPAWS 417
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
258-416 |
8.76e-49 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 163.30 E-value: 8.76e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 258 LAFALSKTGSLNLYVMDLGSGQIRQVTNGRSNNTEPSWFPDSQNLAFTSDQAGRPQVYKVNINGGTPQRITWEGSQNQDA 337
Cdd:COG0823 1 LAFTLSRDGNSDIYVVDLDGGEPRRLTNSPGIDTSPAWSPDGRRIAFTSDRGGGPQIYVVDADGGEPRRLTFGGGYNASP 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490232244 338 DVSADGKTMVMVSSAGGQQHIAKQDLEAGGVQVLSSTFLDetPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRfKARLPA 416
Cdd:COG0823 81 SWSPDGKRLAFVSRSDGRFDIYVLDLDGGAPRRLTDGPGS--PSWSPDGRRIVFSSDRGGRPDLYVVDLDGR-KRRLTP 156
|
|
| TolB_N |
pfam04052 |
TolB amino-terminal domain; TolB is an essential periplasmic component of the tol-dependent ... |
23-121 |
4.61e-41 |
|
TolB amino-terminal domain; TolB is an essential periplasmic component of the tol-dependent translocation system. This function of this amino terminal domain is uncertain.
Pssm-ID: 461148 Cd Length: 105 Bit Score: 141.22 E-value: 4.61e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 23 VRIEITQGVDSARPIGVVPFQWAGQGAAPEDVGGIVAADLRNSGKFNPLDRSRLPQQPGSAQEVQPAAWSALGIDAVVVG 102
Cdd:pfam04052 1 LRIEITGGGDTALPIAVVPFQGEGGADLPQDISEVIAADLERSGLFRPIDPAAFPQRPTSDSEVDFADWRALGADALVTG 80
|
90
....*....|....*....
gi 490232244 103 QVTQNPDGSYNVAYQLVDT 121
Cdd:pfam04052 81 SVTRGGDGRYKVEFRLYDV 99
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
167-328 |
1.13e-35 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 129.02 E-value: 1.13e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 167 IAYVVQTNGGqfpYELRVSDYDGYNQFLVHRSTQPLMSPAWSPDGAKLAYVTFESGRSALVVQTLANGSVRQIASFPQHN 246
Cdd:COG0823 1 LAFTLSRDGN---SDIYVVDLDGGEPRRLTNSPGIDTSPAWSPDGRRIAFTSDRGGGPQIYVVDADGGEPRRLTFGGGYN 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 247 GAPAFSPDGSKLAFALSKTGSLNLYVMDLGSGQIRQVTNGRSNntePSWFPDSQNLAFTSDQAGRPQVYKVNINgGTPQR 326
Cdd:COG0823 78 ASPSWSPDGKRLAFVSRSDGRFDIYVLDLDGGAPRRLTDGPGS---PSWSPDGRRIVFSSDRGGRPDLYVVDLD-GRKRR 153
|
..
gi 490232244 327 IT 328
Cdd:COG0823 154 LT 155
|
|
| tolB |
PRK01029 |
Tol-Pal system protein TolB; |
131-426 |
2.67e-26 |
|
Tol-Pal system protein TolB;
Pssm-ID: 234889 [Multi-domain] Cd Length: 428 Bit Score: 109.85 E-value: 2.67e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 131 QNSFKVTKQYL-------RYAAHAASDAVFEKLTGIKGAFRTRIAYVVQTNGGQFPY---ELRVSDYDGYNQFLVHRSTQ 200
Cdd:PRK01029 106 KNPQKLFSLELsgdlskdRQKIHEAADTIHYALTGVPGISSGKIIFSLSTTNSDTELkqgELWSVDYDGQNLRPLTQEHS 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 201 PLMSPAWSPDGAKLA--YVTFESGRSALVVQTLANGSVRQIASFPQHNGAPAFSPDGSKLAFALSKTGSLNLYV--MDLG 276
Cdd:PRK01029 186 LSITPTWMHIGSGFPylYVSYKLGVPKIFLGSLENPAGKKILALQGNQLMPTFSPRKKLLAFISDRYGNPDLFIqsFSLE 265
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 277 SGQI---RQVTNGR-SNNTEPSWFPDSQNLAFTSDQAGRPQVYKVNIN--GGTPQRITWEGSQNQDADVSADGKTMVMVS 350
Cdd:PRK01029 266 TGAIgkpRRLLNEAfGTQGNPSFSPDGTRLVFVSNKDGRPRIYIMQIDpeGQSPRLLTKKYRNSSCPAWSPDGKKIAFCS 345
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490232244 351 SAGGQQHIAKQDLEAGGVQVLSSTFLD-ETPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRFKARLPATDGQVKSPAW 426
Cdd:PRK01029 346 VIKGVRQICVYDLATGRDYQLTTSPENkESPSWAIDSLHLVYSAGNSNESELYLISLITKKTRKIVIGSGEKRFPSW 422
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
204-351 |
1.04e-22 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 101.27 E-value: 1.04e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 204 SPAWSPDGAKLAYVTFESGRSALVVQTLANGS-VRQIASF-PQHNGAPAFSPDGSKLAFAlskTGSLNLYVMDLGSGQIR 281
Cdd:COG4946 347 LPAWSPDGKSIAYFSDASGEYELYIAPADGSGePKQLTLGdLGRVFNPVWSPDGKKIAFT---DNRGRLWVVDLASGKVR 423
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490232244 282 QVTNGRSN--NTEPSWFPDSQNLAFT-SDQAGRPQVYKVNINGGTPQRITWEGSQNQDADVSADGKTMVMVSS 351
Cdd:COG4946 424 KVDTDGYGdgISDLAWSPDSKWLAYSkPGPNQLSQIFLYDVETGKTVQLTDGRYDDGSPAFSPDGKYLYFLSS 496
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
234-347 |
1.13e-17 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 85.86 E-value: 1.13e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 234 GSVRQIASFPQHNGAPAFSPDGSKLAFALSKTGSLNLYVMDLGSGQIRQVTNGRSNNTEPSWFPDSQNLAFTSDQ----A 309
Cdd:COG4946 51 GRARRLTSHPGYESFPRFSPDGKWIAFTSDYDGNTDVYVMPAEGGEPKRLTYHPANDRVVGWTPDGKSVLFASNRgsppS 130
|
90 100 110
....*....|....*....|....*....|....*....
gi 490232244 310 GRPQVYKVNINGGTPQRITW-EGSqnqDADVSADGKTMV 347
Cdd:COG4946 131 RSNQLYTVPVDGGLPERLPLpPAG---DGSFSPDGKKLA 166
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
203-326 |
1.40e-17 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 85.48 E-value: 1.40e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 203 MSPAWSPDGAKLAYVtfeSGRSALVVQTLANGSVRQIASFPQHNGA--PAFSPDGSKLAFALSKTGSL-NLYVMDLGSGQ 279
Cdd:COG4946 392 FNPVWSPDGKKIAFT---DNRGRLWVVDLASGKVRKVDTDGYGDGIsdLAWSPDSKWLAYSKPGPNQLsQIFLYDVETGK 468
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 490232244 280 IRQVTNGRSNNTEPSWFPDSQNLAFTSDQAGRPQVYKVNINGGTPQR 326
Cdd:COG4946 469 TVQLTDGRYDDGSPAFSPDGKYLYFLSSRDFNPTYGDLDFDLAFPRT 515
|
|
| tolB |
PRK01029 |
Tol-Pal system protein TolB; |
204-335 |
1.80e-17 |
|
Tol-Pal system protein TolB;
Pssm-ID: 234889 [Multi-domain] Cd Length: 428 Bit Score: 84.04 E-value: 1.80e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 204 SPAWSPDGAKLAYVTFESGRSAL-VVQTLANG-SVRQIASFPQHNGAPAFSPDGSKLAFALSKTGSLNLYVMDLGSGQIR 281
Cdd:PRK01029 285 NPSFSPDGTRLVFVSNKDGRPRIyIMQIDPEGqSPRLLTKKYRNSSCPAWSPDGKKIAFCSVIKGVRQICVYDLATGRDY 364
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490232244 282 QVTNGRSNNTEPSWFPDSQNLAFTSDQAGRPQVYKVNINGGTPQRIT----------WEGSQNQ 335
Cdd:PRK01029 365 QLTTSPENKESPSWAIDSLHLVYSAGNSNESELYLISLITKKTRKIVigsgekrfpsWGAFPSQ 428
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
206-428 |
1.88e-15 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 78.93 E-value: 1.88e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 206 AWSPDGAKLAYVT---FESGRSALVVQTLANGSVRQIASFPQHNGApAFSPDGSKLAFAlSKTGSLN------------L 270
Cdd:COG4946 111 GWTPDGKSVLFASnrgSPPSRSNQLYTVPVDGGLPERLPLPPAGDG-SFSPDGKKLAYT-RIGREFRtwkryrggtagdI 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 271 YVMDLGSGQIRQVTNGRSNNTEPSWFPDsqNLAFTSDQAGRPQVYKVNINGGTPQRITwegsQNQDADV---SADGKTMV 347
Cdd:COG4946 189 WIYDLGTGEFTRLTDFGGNDRNPMWIGD--RIYFLSDRDGTFNLYSYDPDGKDLRQLT----HFKDFDVrfpSTDGGRIV 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 348 MvsSAGGQQHiaKQDLEAGGVQVLS----STFLDETP------------SLAPNGTMV-------IYSSSQGMGSVLNLV 404
Cdd:COG4946 263 Y--EQGGDLY--LLDLASGEPRKLNitlaGDFPQRRPrwvdvsgyltsfALSPDGKRVafeargeVFTVPAEKGPTRNLT 338
|
250 260
....*....|....*....|....
gi 490232244 405 STDGrfkarlpatdGQVKSPAWSP 428
Cdd:COG4946 339 NTPG----------VRERLPAWSP 352
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
269-392 |
1.59e-12 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 69.68 E-value: 1.59e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 269 NLYVMDLGSGQIRQVTNGRSNNTEPSWFPDSQNLAFTSDQAGRPQVYKVNINGGTPQRITWEGSQNQDADVSADGKTMVM 348
Cdd:COG4946 42 DLWTVPADGGRARRLTSHPGYESFPRFSPDGKWIAFTSDYDGNTDVYVMPAEGGEPKRLTYHPANDRVVGWTPDGKSVLF 121
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 490232244 349 VSSAG----GQQHIAKQDLEAGGVQVLS---STFLdetpSLAPNGTMVIYS 392
Cdd:COG4946 122 ASNRGsppsRSNQLYTVPVDGGLPERLPlppAGDG----SFSPDGKKLAYT 168
|
|
| tolB |
PRK04043 |
Tol-Pal system protein TolB; |
57-350 |
5.52e-11 |
|
Tol-Pal system protein TolB;
Pssm-ID: 235212 [Multi-domain] Cd Length: 419 Bit Score: 63.86 E-value: 5.52e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 57 IVAADLRNSGKFNPLDRSRlpqqpGSAQEVQPAAWSALGIDAVVVGQVTQNPDGSYNVAYQLVDtgGAPGTVLAQNSFKV 136
Cdd:PRK04043 53 ILVNDLKVSSHFEVSENKD-----QSSGDINYNELKDKKVDLVFRYSLANKNGNKLSLRVKLYD--VNTGSLKFEKDYTI 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 137 TkQYLRY--AAH-AASDA----------------VFEKLTGIKgafRTRIAyvvqtnggqfpyelrVSDY---------- 187
Cdd:PRK04043 126 N-SLDRYpfLAHkSAIDIndylkapsidwmkrkvVFSKYTGPK---KSNIV---------------LADYtltyqkvivk 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 188 DGYNQFlvhrstqplmsPAWSPDGAKLAYVTFESGRS-ALVVQTLANGSVRQIASfpqHNG---APAFSPDGSKLAFALS 263
Cdd:PRK04043 187 GGLNIF-----------PKWANKEQTAFYYTSYGERKpTLYKYNLYTGKKEKIAS---SQGmlvVSDVSKDGSKLLLTMA 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 264 KTGSLNLYVMDLGSGQIRQVTNGRSNNTEPSWFPDSQNLAFTSDQAGRPQVYKVNINGGTPQRITWEGsQNQDAdVSADG 343
Cdd:PRK04043 253 PKGQPDIYLYDTNTKTLTQITNYPGIDVNGNFVEDDKRIVFVSDRLGYPNIFMKKLNSGSVEQVVFHG-KNNSS-VSTYK 330
|
....*..
gi 490232244 344 KTMVMVS 350
Cdd:PRK04043 331 NYIVYSS 337
|
|
| PD40 |
pfam07676 |
WD40-like Beta Propeller Repeat; This family appears to be related to the pfam00400 repeat. ... |
280-316 |
1.24e-09 |
|
WD40-like Beta Propeller Repeat; This family appears to be related to the pfam00400 repeat. This repeat corresponds to the RIVW repeat identified in cell surface proteins [Adindla et al. Comparative and Functional Genomics 2004; 5:2-16].
Pssm-ID: 429587 [Multi-domain] Cd Length: 37 Bit Score: 53.29 E-value: 1.24e-09
10 20 30
....*....|....*....|....*....|....*..
gi 490232244 280 IRQVTNGRSNNTEPSWFPDSQNLAFTSDQAGRPQVYK 316
Cdd:pfam07676 1 LGRLTNTPGNETAPSWSPDGKRLAFSSDRDGKPDIYV 37
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
252-430 |
3.04e-09 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 59.28 E-value: 3.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 252 SPDGSKLAFALSktGslNLYVMDLGSGQIRQVTN--GrSNNTEPSWFPDSQNLAFTSDQAGRPQVYKVNING-GTPQRIT 328
Cdd:COG4946 310 SPDGKRVAFEAR--G--EVFTVPAEKGPTRNLTNtpG-VRERLPAWSPDGKSIAYFSDASGEYELYIAPADGsGEPKQLT 384
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 329 WEGS-QNQDADVSADGKTMVmVSSAGGQQHIAkqDLEAGGV-QVLSSTFLDETPSLA--PNGTMVIYSSSQGMG-SVLNL 403
Cdd:COG4946 385 LGDLgRVFNPVWSPDGKKIA-FTDNRGRLWVV--DLASGKVrKVDTDGYGDGISDLAwsPDSKWLAYSKPGPNQlSQIFL 461
|
170 180 190
....*....|....*....|....*....|..
gi 490232244 404 VSTDGrfKARLPATDGQVK--SPAWSP---YL 430
Cdd:COG4946 462 YDVET--GKTVQLTDGRYDdgSPAFSPdgkYL 491
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
182-428 |
5.16e-08 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 54.53 E-value: 5.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 182 LRVSDYDGYNQFLVHRSTQPLMSPAWSPDGAKLAYVtfeSGRSALVVQTLANGsvRQIASFPQHNGAP---AFSPDGSKL 258
Cdd:COG2319 61 LLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASA---SADGTVRLWDLATG--LLLRTLTGHTGAVrsvAFSPDGKTL 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 259 AFAlSKTGSLNLYvmDLGSGQIRQVTNGRSNNTEP-SWFPDSQNLAFTSDQAgrpQVYKVNINGGTPQRiTWEGSQN--Q 335
Cdd:COG2319 136 ASG-SADGTVRLW--DLATGKLLRTLTGHSGAVTSvAFSPDGKLLASGSDDG---TVRLWDLATGKLLR-TLTGHTGavR 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 336 DADVSADGKTMVmvssAGGQQHIAKQ-DLEAGGVQVLSSTFLDETPSLA--PNGTMVIYSSSQGMGSVLNLvsTDGRFKA 412
Cdd:COG2319 209 SVAFSPDGKLLA----SGSADGTVRLwDLATGKLLRTLTGHSGSVRSVAfsPDGRLLASGSADGTVRLWDL--ATGELLR 282
|
250
....*....|....*.
gi 490232244 413 RLPATDGQVKSPAWSP 428
Cdd:COG2319 283 TLTGHSGGVNSVAFSP 298
|
|
| PD40 |
pfam07676 |
WD40-like Beta Propeller Repeat; This family appears to be related to the pfam00400 repeat. ... |
236-272 |
5.68e-08 |
|
WD40-like Beta Propeller Repeat; This family appears to be related to the pfam00400 repeat. This repeat corresponds to the RIVW repeat identified in cell surface proteins [Adindla et al. Comparative and Functional Genomics 2004; 5:2-16].
Pssm-ID: 429587 [Multi-domain] Cd Length: 37 Bit Score: 48.67 E-value: 5.68e-08
10 20 30
....*....|....*....|....*....|....*..
gi 490232244 236 VRQIASFPQHNGAPAFSPDGSKLAFALSKTGSLNLYV 272
Cdd:pfam07676 1 LGRLTNTPGNETAPSWSPDGKRLAFSSDRDGKPDIYV 37
|
|
| Peptidase_S9_N |
pfam02897 |
Prolyl oligopeptidase, N-terminal beta-propeller domain; This unusual 7-stranded ... |
247-352 |
1.34e-05 |
|
Prolyl oligopeptidase, N-terminal beta-propeller domain; This unusual 7-stranded beta-propeller domain protects the catalytic triad of prolyl oligopeptidase (see pfam00326), excluding larger peptides and proteins from proteolysis in the cytosol.
Pssm-ID: 397164 [Multi-domain] Cd Length: 414 Bit Score: 46.92 E-value: 1.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 247 GAPAFSPDGSKLAFALSKTGS--LNLYVMDLGSGQ-IRQVTNGrSNNTEPSWFPDSQNLAFTS--DQAGRP--------Q 313
Cdd:pfam02897 127 GGFAFSPDGRLLAYSLSLSGSdwYTIRFRDVETGEdLPDVLEG-VKFSGIVWAPDGKGFFYTRydKPDERSdtgtnlnqK 205
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 490232244 314 VYKVNIngGTPQ---RITWEGSQNQD----ADVSADGKTmVMVSSA 352
Cdd:pfam02897 206 VWRHRL--GTPQsqdVLVFEFPKDPLwslgAERSEDGKY-LFISSA 248
|
|
| DPPIV_N |
pfam00930 |
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ... |
195-411 |
3.06e-05 |
|
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.
Pssm-ID: 395744 [Multi-domain] Cd Length: 352 Bit Score: 45.77 E-value: 3.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 195 VHRSTQPLMSPAWSPDGAKLAYVtFESGrsaLVVQTLANGSVRQIASFPQ---HNGAP---------------AFSPDGS 256
Cdd:pfam00930 38 LPPGEGKIQDAKWSPDGDRLAFV-RDNN---LYVRELATGKEIQITSDGSdgiFNGVAdwvyeeevlgsnsavWWSPDGS 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 257 KLAFA----------------------------LSKTGSLN----LYVMDLGSGQIRQVTNGRSNNTEP------SWFPD 298
Cdd:pfam00930 114 RLAFLrfdesevpiitlpyytdegpgpevreikYPKAGAPNptveLFVYDLASGKTVEVVPPDDLSDADyyitrvKWVPD 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 299 SqNLAFTsdQAGRPQ----VYKVNINGGTPQRI------TWEGSQNQDADVSADGKTMVMVSSAGGQQHIAKQDLEAGGV 368
Cdd:pfam00930 194 G-KLLVQ--WLNRDQnrlkVVLCDAETGRTVVIleetsdGWVELHQDPHFIKRDGSGFLWISERDGYNHLYLYDLDGKSP 270
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 490232244 369 QVLSSTFLDETPSLAPNGTM--VIYSSSQGMGSVLNL--VSTDGRFK 411
Cdd:pfam00930 271 IQLTSGNWEVTSILGVDETRdlVYFTATEDSPTERHLysVSLDSGGE 317
|
|
| Pectate_lyase22 |
pfam14583 |
Oligogalacturonate lyase; This is a family of oligogalacturonate lyases, referred to more ... |
188-315 |
7.09e-05 |
|
Oligogalacturonate lyase; This is a family of oligogalacturonate lyases, referred to more generally as pectate lyase family 22. These proteins fold into 7-bladed beta-propellers.
Pssm-ID: 434052 [Multi-domain] Cd Length: 386 Bit Score: 44.62 E-value: 7.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 188 DGYNQFLV--HRSTQPLMSPAWSPDGAKLAYVTFESGRSALVV-----QTLANgsvRQIASFP-------QHNGAPAFSp 253
Cdd:pfam14583 224 DGSNMRKVktHAEGESCTHEFWVPDGSALVYVSYLKGSTDRFIysadpVTLEN---RQLTSMPacshlmsNYDGTLMVG- 299
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490232244 254 DGSKLAFALSKTGSLN------LYVMDLGSGQIRQVTNGRSN-----------NTEPSWFPDSQNLAFTSDQAGRPQVY 315
Cdd:pfam14583 300 DGSDAPVDVQDDSGYKiendpfLYVFNMKNGTQHRVARHDTSwevfegdrqvtHPHPSFTPDDKQILFTSDVHGKPALY 378
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
199-353 |
1.15e-04 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 44.13 E-value: 1.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 199 TQPLMSPAWSPDGAKLAYVtfeSGRSALVVQTLANGsvRQIASFPQHNGAP---AFSPDGSKLAFAlSKTGSLNLYvmDL 275
Cdd:COG2319 246 SGSVRSVAFSPDGRLLASG---SADGTVRLWDLATG--ELLRTLTGHSGGVnsvAFSPDGKLLASG-SDDGTVRLW--DL 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 276 GSGQIRQVTNGRSNNTEP-SWFPDSQNLAFTSDQAGrpqVYKVNINGGTPQRiTWEGSQNQ--DADVSADGKTMVMVSSA 352
Cdd:COG2319 318 ATGKLLRTLTGHTGAVRSvAFSPDGKTLASGSDDGT---VRLWDLATGELLR-TLTGHTGAvtSVAFSPDGRTLASGSAD 393
|
.
gi 490232244 353 G 353
Cdd:COG2319 394 G 394
|
|
| Pectate_lyase22 |
pfam14583 |
Oligogalacturonate lyase; This is a family of oligogalacturonate lyases, referred to more ... |
251-307 |
1.93e-04 |
|
Oligogalacturonate lyase; This is a family of oligogalacturonate lyases, referred to more generally as pectate lyase family 22. These proteins fold into 7-bladed beta-propellers.
Pssm-ID: 434052 [Multi-domain] Cd Length: 386 Bit Score: 43.47 E-value: 1.93e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 490232244 251 FSPDGSKLAFALSKTGSLNLYVMDLGSGQIRQVTNGRSNNTEPSWF-PDSQNLAFTSD 307
Cdd:pfam14583 43 FTRDGSKLLFGGAFDGPWNYYLLDLNTQVATQLTEGRGDNTFGGFLsPDDDALFYVKD 100
|
|
| DPPIV_N |
pfam00930 |
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ... |
252-332 |
8.99e-04 |
|
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.
Pssm-ID: 395744 [Multi-domain] Cd Length: 352 Bit Score: 41.15 E-value: 8.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490232244 252 SPDGSKLAFALSKT------GSLNLYVMDLGSGQIRQVTNGRSNNTEPSWFPDSQNLAFTSDQagrpQVYKVNINGGTPQ 325
Cdd:pfam00930 1 SPDGKYLLLATNYTknwrhsYTADYYIYDLETNRVEPLPPGEGKIQDAKWSPDGDRLAFVRDN----NLYVRELATGKEI 76
|
....*..
gi 490232244 326 RITWEGS 332
Cdd:pfam00930 77 QITSDGS 83
|
|
| |
