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Conserved domains on  [gi|490219748|ref|WP_004118124|]
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MULTISPECIES: type I toxin-antitoxin system Hok family toxin [Bacteria]

Protein Classification

type I toxin-antitoxin system Hok family toxin( domain architecture ID 10013329)

type I toxin-antitoxin system Hok family toxin similar to Hok, a small, toxic protein encoded on the parB (hok/sok) locus of plasmid R1, that mediates plasmid stabilization by killing plasmid-free cells

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK09738 PRK09738
small toxic polypeptide; Provisional
 1-50 7.44e-22

small toxic polypeptide; Provisional


:

Pssm-ID: 182055  Cd Length: 52  Bit Score: 78.29  E-value: 7.44e-22
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 490219748  1 MKLPRNALVWCVLIVCLTLLIFTCLTRNRLCEVRLKDGNREVAASLAYES 50
Cdd:PRK09738  1 MKLPRSPLVWCVLIVCLTLLIFTYLTRKSLCELRYRDGDREVAAFMAYES 50
 
Name Accession Description Interval E-value
PRK09738 PRK09738
small toxic polypeptide; Provisional
 1-50 7.44e-22

small toxic polypeptide; Provisional


Pssm-ID: 182055  Cd Length: 52  Bit Score: 78.29  E-value: 7.44e-22
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 490219748  1 MKLPRNALVWCVLIVCLTLLIFTCLTRNRLCEVRLKDGNREVAASLAYES 50
Cdd:PRK09738  1 MKLPRSPLVWCVLIVCLTLLIFTYLTRKSLCELRYRDGDREVAAFMAYES 50
HOK_GEF pfam01848
Hok/gef family;
8-48 2.73e-09

Hok/gef family;


Pssm-ID: 426473  Cd Length: 41  Bit Score: 46.60  E-value: 2.73e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 490219748   8 LVWCVLIVCLTLLIFTCLTRNRLCEVRLKDGNREVAASLAY 48
Cdd:pfam01848  1 ALVALIVICITVLLFTLVTRKSLCELRIRQGQTEVAAFLAC 41
 
Name Accession Description Interval E-value
PRK09738 PRK09738
small toxic polypeptide; Provisional
 1-50 7.44e-22

small toxic polypeptide; Provisional


Pssm-ID: 182055  Cd Length: 52  Bit Score: 78.29  E-value: 7.44e-22
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 490219748  1 MKLPRNALVWCVLIVCLTLLIFTCLTRNRLCEVRLKDGNREVAASLAYES 50
Cdd:PRK09738  1 MKLPRSPLVWCVLIVCLTLLIFTYLTRKSLCELRYRDGDREVAAFMAYES 50
HOK_GEF pfam01848
Hok/gef family;
8-48 2.73e-09

Hok/gef family;


Pssm-ID: 426473  Cd Length: 41  Bit Score: 46.60  E-value: 2.73e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 490219748   8 LVWCVLIVCLTLLIFTCLTRNRLCEVRLKDGNREVAASLAY 48
Cdd:pfam01848  1 ALVALIVICITVLLFTLVTRKSLCELRIRQGQTEVAAFLAC 41
PRK09759 PRK09759
type I toxin-antitoxin system toxin HokA;
3-47 6.52e-07

type I toxin-antitoxin system toxin HokA;


Pssm-ID: 182063  Cd Length: 50  Bit Score: 40.68  E-value: 6.52e-07
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*
gi 490219748  3 LPRNALVWCVLIVCLTLLIFTCLTRNRLCEVRLKDGNREVAASLA 47
Cdd:PRK09759  1 MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQGSYELAAFLA 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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