|
Name |
Accession |
Description |
Interval |
E-value |
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
2-319 |
0e+00 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 595.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 2 IKKIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVFGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDEH 81
Cdd:PRK03202 1 MKRIGVLTSGGDAPGMNAAIRAVVRTAISEGLEVYGIYDGYAGLLEGDIVKLDLKSVSDIINRGGTILGSARFPEFKDEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 82 IREVAIENMKKRGLDALVVIGGDGSYMGAKRLTEMGFPCIGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDRLRDTSSSH 161
Cdd:PRK03202 81 GRAKAIENLKKLGIDALVVIGGDGSYMGAKRLTEHGIPVIGLPGTIDNDIAGTDYTIGFDTALNTAVEAIDRLRDTASSH 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 162 QRISIVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVAEIKAGIAKGKKHAIVAITEHICDVDELAKYIETETKR 241
Cdd:PRK03202 161 ERVFIVEVMGRHAGDLALHAGIAGGAEVILIPEVPFDIEELCAKIKKGRERGKKHAIIVVAEGVMPAEELAKEIEERTGL 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489958702 242 ETRATVLGHIQRGGSPGPYDRILASRMGAYAIELLLQGHGGRCVGIQNEKLVHHDIIDAIENMKRPFKGDWLDCAKKL 319
Cdd:PRK03202 241 ETRVTVLGHIQRGGSPTAFDRVLASRMGAHAVELLLEGKGGRMVGIQNNKIVHVPIEEAVENMKHPFDKDLYELAKKL 318
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
3-320 |
0e+00 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 557.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 3 KKIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVFGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDEHI 82
Cdd:cd00763 1 KRIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIRDGYAGLIAGDIVPLDRYSVSDIINRGGTFLGSARFPEFKDEEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 83 REVAIENMKKRGLDALVVIGGDGSYMGAKRLTEMGFPCIGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDRLRDTSSSHQ 162
Cdd:cd00763 81 QAKAIEQLKKHGIDALVVIGGDGSYMGAMRLTEHGFPCVGLPGTIDNDIPGTDYTIGFDTALNTVVEAIDRIRDTSSSHQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 163 RISIVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVAEIKAGIAKGKKHAIVAITEHICDVDELAKYIETETKRE 242
Cdd:cd00763 161 RISVVEVMGRHCGDIALAAGIAGGAEFIVIPEAEFDREEVANRIKAGIERGKKHAIVVVAEGVYDVDELAKEIEEATGFE 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489958702 243 TRATVLGHIQRGGSPGPYDRILASRMGAYAIELLLQGHGGRCVGIQNEKLVHHDIIDAIENMKrPFKGDWLDCAKKLY 320
Cdd:cd00763 241 TRATVLGHIQRGGSPTAFDRILASRMGAYAVELLLAGKGGLAVGIQNEQLVHHDIIDAIENMK-PFKKDWLALAKKLS 317
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
2-319 |
1.92e-163 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 458.77 E-value: 1.92e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 2 IKKIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVFGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDEH 81
Cdd:COG0205 1 MKRIGILTSGGDAPGLNAAIRAVVRTAIKYGIEVYGIRDGYEGLLEGDIIDLTREDVSGILQRGGTILGSSRSKPFKTEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 82 IREVAIENMKKRGLDALVVIGGDGSYMGAKRLTE-MGFPCIGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDRLRDTSSS 160
Cdd:COG0205 81 GREKALENLKKLGIDALVVIGGDGSLDGAAKLAEeYGIPVVGIPKTIDNDLPGTDYTIGFDTAVNTAAEAIDRLRDTAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 161 HQRISIVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVAEIKAGIAKGKKHAIVAITEHICDVD----------- 229
Cdd:COG0205 161 HERVFVVEVMGRHAGWLALAAGLAGGADLILIPEVPFDLDKLLEKLKERRKRGKGYSIIVVAEGAGDEDgeavleadtda 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 230 -----------ELAKYIETETKRETRATVLGHIQRGGSPGPYDRILASRMGAYAIELLLQGHGGRCVGIQNEKLVHHDII 298
Cdd:COG0205 241 fghvrlggigeYLAKEIEERTGIETRVTVLGHLQRGGSPSAFDRVLASRLGAAAVELLLEGKTGVMVGIRRGEIVLVPLE 320
|
330 340
....*....|....*....|..
gi 489958702 299 DAIENMKR-PFKGDWLDCAKKL 319
Cdd:COG0205 321 EVANKEKPvDPDSPLIQLAREL 342
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
4-274 |
1.14e-153 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 430.99 E-value: 1.14e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 4 KIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVFGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDEHIR 83
Cdd:pfam00365 1 RIGILTSGGDAPGMNAAIRAVVRTAIYRGHEVYGIRNGYEGLVEGDIDELTWRDVSGILNRGGTILGTSRSKPFKTEEGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 84 EVAIENMKKRGLDALVVIGGDGSYMGAKRLT-EMGFPCIGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDRLRDTSSSHQ 162
Cdd:pfam00365 81 EKIAENLKKLGIDALVVIGGDGSLTGANKLSeERGIPVVGIPKTIDNDIPGTDYTIGFDTALNTIVEAIDRIRDTASSHN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 163 RISIVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVAEIKAGIaKGKKHAIVAITEHICDVDELAKYIETETKRE 242
Cdd:pfam00365 161 RVFVVEVMGRHCGWLALMAGLAGGADAILIPEIPFDIEELCEKIKELR-KGKRFSIIVVAEGASDGEFLAKLIEEGTGIE 239
|
250 260 270
....*....|....*....|....*....|..
gi 489958702 243 TRATVLGHIQRGGSPGPYDRILASRMGAYAIE 274
Cdd:pfam00365 240 TRVTVLGHVQRGGTPSAFDRILATRLGVKAVE 271
|
|
| PFKA_ATP |
TIGR02482 |
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate ... |
4-301 |
6.17e-144 |
|
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate from ATP to fructose 6-phosphate to give fructose 1,6-bisphosphate. This represents a key control step in glycolysis. This model hits bacterial ATP-dependent 6-phosphofructokinases which lack a beta-hairpin loop present in TIGR02483 family members. TIGR02483 contains members that are ATP-dependent as well as members that are pyrophosphate-dependent. TIGR02477 represents the pyrophosphate-dependent phosphofructokinase, diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90). [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213713 [Multi-domain] Cd Length: 301 Bit Score: 407.89 E-value: 6.17e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 4 KIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVFGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDEHIR 83
Cdd:TIGR02482 1 KIGILTSGGDAPGMNAAIRAVVRTAIYHGFEVYGIRRGYKGLINGKIEPLESKNVSGIIHRGGTILGTARCPEFKTEEVR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 84 EVAIENMKKRGLDALVVIGGDGSYMGAKRLTEMG-FPCIGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDRLRDTSSSHQ 162
Cdd:TIGR02482 81 EKAVENLKKLGIEGLVVIGGDGSYTGAQKLYEEGgIPVIGLPGTIDNDIPGTDYTIGFDTALNTIIDAVDKIRDTATSHE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 163 RISIVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVAEIKAGIAKGKKHA-IVAITEHICD-VDELAKYIETETK 240
Cdd:TIGR02482 161 RAFVIEVMGRHAGDLALYAGIATGAEIIIIPEFDYDIDELIQRLKEQHEAGKKHSiIIVAEGNIVGsAKEVAKKIEEKTG 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489958702 241 RETRATVLGHIQRGGSPGPYDRILASRMGAYAIELLLQGHGGRCVGIQNEKLVHHDIIDAI 301
Cdd:TIGR02482 241 IETRVTVLGHTQRGGSPSAFDRVLASRLGAKAVELLLEGKGGVMIGIQNNKIVTHPIEEAL 301
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
2-319 |
0e+00 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 595.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 2 IKKIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVFGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDEH 81
Cdd:PRK03202 1 MKRIGVLTSGGDAPGMNAAIRAVVRTAISEGLEVYGIYDGYAGLLEGDIVKLDLKSVSDIINRGGTILGSARFPEFKDEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 82 IREVAIENMKKRGLDALVVIGGDGSYMGAKRLTEMGFPCIGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDRLRDTSSSH 161
Cdd:PRK03202 81 GRAKAIENLKKLGIDALVVIGGDGSYMGAKRLTEHGIPVIGLPGTIDNDIAGTDYTIGFDTALNTAVEAIDRLRDTASSH 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 162 QRISIVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVAEIKAGIAKGKKHAIVAITEHICDVDELAKYIETETKR 241
Cdd:PRK03202 161 ERVFIVEVMGRHAGDLALHAGIAGGAEVILIPEVPFDIEELCAKIKKGRERGKKHAIIVVAEGVMPAEELAKEIEERTGL 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489958702 242 ETRATVLGHIQRGGSPGPYDRILASRMGAYAIELLLQGHGGRCVGIQNEKLVHHDIIDAIENMKRPFKGDWLDCAKKL 319
Cdd:PRK03202 241 ETRVTVLGHIQRGGSPTAFDRVLASRMGAHAVELLLEGKGGRMVGIQNNKIVHVPIEEAVENMKHPFDKDLYELAKKL 318
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
3-320 |
0e+00 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 557.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 3 KKIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVFGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDEHI 82
Cdd:cd00763 1 KRIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIRDGYAGLIAGDIVPLDRYSVSDIINRGGTFLGSARFPEFKDEEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 83 REVAIENMKKRGLDALVVIGGDGSYMGAKRLTEMGFPCIGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDRLRDTSSSHQ 162
Cdd:cd00763 81 QAKAIEQLKKHGIDALVVIGGDGSYMGAMRLTEHGFPCVGLPGTIDNDIPGTDYTIGFDTALNTVVEAIDRIRDTSSSHQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 163 RISIVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVAEIKAGIAKGKKHAIVAITEHICDVDELAKYIETETKRE 242
Cdd:cd00763 161 RISVVEVMGRHCGDIALAAGIAGGAEFIVIPEAEFDREEVANRIKAGIERGKKHAIVVVAEGVYDVDELAKEIEEATGFE 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489958702 243 TRATVLGHIQRGGSPGPYDRILASRMGAYAIELLLQGHGGRCVGIQNEKLVHHDIIDAIENMKrPFKGDWLDCAKKLY 320
Cdd:cd00763 241 TRATVLGHIQRGGSPTAFDRILASRMGAYAVELLLAGKGGLAVGIQNEQLVHHDIIDAIENMK-PFKKDWLALAKKLS 317
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
3-318 |
1.27e-163 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 459.07 E-value: 1.27e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 3 KKIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVFGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDEHI 82
Cdd:cd00363 1 KKIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIYEGYAGLVEGDIKELDWESVSDIINRGGTIIGSARCKEFRTEEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 83 REVAIENMKKRGLDALVVIGGDGSYMGAKRLTEM------GFPCIGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDRLRD 156
Cdd:cd00363 81 RAKAAENLKKHGIDALVVIGGDGSYTGADLLTEEwpskyqGFNVIGLPGTIDNDIKGTDYTIGFDTALKTIVEAIDRIRD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 157 TSSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEF---SREDLVAEIKAGIAKGKKHAIVAITEHICD------ 227
Cdd:cd00363 161 TASSHQRTFVVEVMGRHCGDIALEAGLATGADIIFIPEEPAadeWEEEMVDVIKKRRERGKRHGIVIVAEGAIDfipkpi 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 228 -VDELAKYIETETKRETRATVLGHIQRGGSPGPYDRILASRMGAYAIELLLQGHGGRCVGIQNE---KLVHHDIIDAIEN 303
Cdd:cd00363 241 tEKLLAKLVEERLGFDTRATVLGHVQRGGTPTAFDRILASRLGAEAVELLLEGTGGTPVGIQNLnenQVVRHPLTEAVNM 320
|
330
....*....|....*...
gi 489958702 304 MKR---PFKGDWLDCAKK 318
Cdd:cd00363 321 TKRvgvDLEGRPFKKFAK 338
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
2-319 |
1.92e-163 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 458.77 E-value: 1.92e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 2 IKKIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVFGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDEH 81
Cdd:COG0205 1 MKRIGILTSGGDAPGLNAAIRAVVRTAIKYGIEVYGIRDGYEGLLEGDIIDLTREDVSGILQRGGTILGSSRSKPFKTEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 82 IREVAIENMKKRGLDALVVIGGDGSYMGAKRLTE-MGFPCIGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDRLRDTSSS 160
Cdd:COG0205 81 GREKALENLKKLGIDALVVIGGDGSLDGAAKLAEeYGIPVVGIPKTIDNDLPGTDYTIGFDTAVNTAAEAIDRLRDTAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 161 HQRISIVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVAEIKAGIAKGKKHAIVAITEHICDVD----------- 229
Cdd:COG0205 161 HERVFVVEVMGRHAGWLALAAGLAGGADLILIPEVPFDLDKLLEKLKERRKRGKGYSIIVVAEGAGDEDgeavleadtda 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 230 -----------ELAKYIETETKRETRATVLGHIQRGGSPGPYDRILASRMGAYAIELLLQGHGGRCVGIQNEKLVHHDII 298
Cdd:COG0205 241 fghvrlggigeYLAKEIEERTGIETRVTVLGHLQRGGSPSAFDRVLASRLGAAAVELLLEGKTGVMVGIRRGEIVLVPLE 320
|
330 340
....*....|....*....|..
gi 489958702 299 DAIENMKR-PFKGDWLDCAKKL 319
Cdd:COG0205 321 EVANKEKPvDPDSPLIQLAREL 342
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
4-274 |
1.14e-153 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 430.99 E-value: 1.14e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 4 KIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVFGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDEHIR 83
Cdd:pfam00365 1 RIGILTSGGDAPGMNAAIRAVVRTAIYRGHEVYGIRNGYEGLVEGDIDELTWRDVSGILNRGGTILGTSRSKPFKTEEGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 84 EVAIENMKKRGLDALVVIGGDGSYMGAKRLT-EMGFPCIGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDRLRDTSSSHQ 162
Cdd:pfam00365 81 EKIAENLKKLGIDALVVIGGDGSLTGANKLSeERGIPVVGIPKTIDNDIPGTDYTIGFDTALNTIVEAIDRIRDTASSHN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 163 RISIVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVAEIKAGIaKGKKHAIVAITEHICDVDELAKYIETETKRE 242
Cdd:pfam00365 161 RVFVVEVMGRHCGWLALMAGLAGGADAILIPEIPFDIEELCEKIKELR-KGKRFSIIVVAEGASDGEFLAKLIEEGTGIE 239
|
250 260 270
....*....|....*....|....*....|..
gi 489958702 243 TRATVLGHIQRGGSPGPYDRILASRMGAYAIE 274
Cdd:pfam00365 240 TRVTVLGHVQRGGTPSAFDRILATRLGVKAVE 271
|
|
| PFKA_ATP |
TIGR02482 |
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate ... |
4-301 |
6.17e-144 |
|
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate from ATP to fructose 6-phosphate to give fructose 1,6-bisphosphate. This represents a key control step in glycolysis. This model hits bacterial ATP-dependent 6-phosphofructokinases which lack a beta-hairpin loop present in TIGR02483 family members. TIGR02483 contains members that are ATP-dependent as well as members that are pyrophosphate-dependent. TIGR02477 represents the pyrophosphate-dependent phosphofructokinase, diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90). [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213713 [Multi-domain] Cd Length: 301 Bit Score: 407.89 E-value: 6.17e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 4 KIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVFGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDEHIR 83
Cdd:TIGR02482 1 KIGILTSGGDAPGMNAAIRAVVRTAIYHGFEVYGIRRGYKGLINGKIEPLESKNVSGIIHRGGTILGTARCPEFKTEEVR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 84 EVAIENMKKRGLDALVVIGGDGSYMGAKRLTEMG-FPCIGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDRLRDTSSSHQ 162
Cdd:TIGR02482 81 EKAVENLKKLGIEGLVVIGGDGSYTGAQKLYEEGgIPVIGLPGTIDNDIPGTDYTIGFDTALNTIIDAVDKIRDTATSHE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 163 RISIVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVAEIKAGIAKGKKHA-IVAITEHICD-VDELAKYIETETK 240
Cdd:TIGR02482 161 RAFVIEVMGRHAGDLALYAGIATGAEIIIIPEFDYDIDELIQRLKEQHEAGKKHSiIIVAEGNIVGsAKEVAKKIEEKTG 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489958702 241 RETRATVLGHIQRGGSPGPYDRILASRMGAYAIELLLQGHGGRCVGIQNEKLVHHDIIDAI 301
Cdd:TIGR02482 241 IETRVTVLGHTQRGGSPSAFDRVLASRLGAKAVELLLEGKGGVMIGIQNNKIVTHPIEEAL 301
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
3-305 |
1.99e-87 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 277.30 E-value: 1.99e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 3 KKIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVFGIYDGYLGLYE--DRMVQLDRYSVSDMINRGGTFLGSARFPEFRDE 80
Cdd:TIGR02478 1 KRIAVLTSGGDAQGMNAAVRAVVRMAIYVGCRVYAIREGYQGLVDggDNIEEAQWEDVRGILSLGGTIIGTARCKEFRER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 81 HIREVAIENMKKRGLDALVVIGGDGSYMGA-----------KRLTEMG------------FPCIGLPGTIDNDIKGTDYT 137
Cdd:TIGR02478 81 PGRLKAARNLVSNGIDALVVIGGDGSLTGAdlfreewpsllEELVDTGkitaeqaeehrhLTIVGLVGSIDNDMCGTDMT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 138 IGYFTALGTVVEAIDRLRDTSSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFVVVPEV---EFSREDLVAEIKAGIAKGK 214
Cdd:TIGR02478 161 IGADSALHRICEAIDAISSTAQSHQRAFVVEVMGRHCGYLALMAAIATGADYVFIPERppeEGWEDQLCHKLKRNRKAGK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 215 KHAIVAITEHICD-------VDELAKYIETETKRETRATVLGHIQRGGSPGPYDRILASRMGAYAIELLLQGHG---GRC 284
Cdd:TIGR02478 241 RKTIVIVAEGAIDrdlnpitSEDVKDVLVERLGLDTRITVLGHVQRGGAPSAFDRILATRQGVEAVLAVLESTPetpSPV 320
|
330 340
....*....|....*....|.
gi 489958702 285 VGIQNEKLVHHDIIDAIENMK 305
Cdd:TIGR02478 321 ISLRGNKIVRKPLVEAVAQTK 341
|
|
| PRK14071 |
PRK14071 |
ATP-dependent 6-phosphofructokinase; |
2-302 |
4.56e-83 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 184487 [Multi-domain] Cd Length: 360 Bit Score: 255.00 E-value: 4.56e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 2 IKKIGVLTSGGDAPGMNAAIRGVV-RAALTEGLEVFGIYDGYLGLYED--RMVQLDRYSVSDMINRGGTFLGSAR----- 73
Cdd:PRK14071 4 KKRIGILTSGGDCAGLNAVIRAVVhRARGTYGWEVIGIRDATQGLMARppQYIELDLDQVDDLLRMGGTILGTTNkgdpf 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 74 -FP----EFRDEhiREVAIENMKKRGLDALVVIGGDGSYMGAKRLTEMG-FPCIGLPGTIDNDIKGTDYTIGYFTALGTV 147
Cdd:PRK14071 84 aFPmpdgSLRDR--SQEIIDGYHSLGLDALIGIGGDGSLAILRRLAQQGgINLVGIPKTIDNDVGATEVSIGFDTAVNIA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 148 VEAIDRLRDTSSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVAEIKAGIAKGKKHAIVAITEHICD 227
Cdd:PRK14071 162 TEALDRLHFTAASHNRVMILEVMGRDAGHIALAAGIAGGADVILIPEIPYTLENVCKKIRERQEEGKNFCLVVVSEAVRT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 228 VD--------------------ELAKYIETETKRETRATVLGHIQRGGSPGPYDRILASRMGAYAIELLLQGHGGRCVGI 287
Cdd:PRK14071 242 EEgeqvtktqalgedryggigqYLAEQIAERTGAETRVTVLGHIQRGGIPSPRDRLLASAFGVAAVDLIAQGKFDRMVAW 321
|
330
....*....|....*
gi 489958702 288 QNEKLVHHDIIDAIE 302
Cdd:PRK14071 322 QNRQVVSVPIAEAIA 336
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
3-279 |
4.17e-74 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 242.42 E-value: 4.17e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 3 KKIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVFGIYDGYLGLYE--DRMVQLDRYSVSDMINRGGTFLGSARFPEFRDE 80
Cdd:cd00764 4 KAIAVLTSGGDAQGMNAAVRAVVRMGIYVGAKVFFVYEGYEGLVKggDYIKQAEWESVSNWLQEGGTIIGSARCKEFRER 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 81 HIREVAIENMKKRGLDALVVIGGDGSYMGAK-----------------RLTEMGFP------CIGLPGTIDNDIKGTDYT 137
Cdd:cd00764 84 EGRLQAAYNLIQRGITNLCVIGGDGSLTGADlfrsewpslleelvkdgKITEEEVAkyqhlnIVGMVGSIDNDFCGTDMT 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 138 IGYFTALGTVVEAIDRLRDTSSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSR---EDLVAEIKAGIAKGK 214
Cdd:cd00764 164 IGTDSALHRICEVVDAITTTAQSHQRTFVLEVMGRHCGYLALVSGLATGADWIFIPERPPEDgweDQMCRRLSEHRSRGK 243
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489958702 215 KHAIVAITEHICDVD-------ELAKYIETETKRETRATVLGHIQRGGSPGPYDRILASRMGAYAIELLLQG 279
Cdd:cd00764 244 RLNIIIVAEGAIDDQlkpitseDVKDLVVERLGLDTRVTTLGHVQRGGTPSAFDRILASLMGVEAVMALLEA 315
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
3-277 |
4.04e-55 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 191.01 E-value: 4.04e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 3 KKIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVFGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARfpEFRDEHI 82
Cdd:TIGR02478 390 LRIAIIHVGAPAGGMNAATRSAVRYALARGHTVIAIHNGFSGLARHDVRELTWSDVEGWVGEGGSELGTNR--SLPGDDL 467
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 83 REVAiENMKKRGLDALVVIGGDGSYMGAKRL-------TEMGFPCIGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDRLR 155
Cdd:TIGR02478 468 GTIA-YYFQQHKIDGLIIIGGFEAFEALYQLdaarekyPAFRIPMVVIPATISNNVPGTEYSLGSDTALNEITEYCDNIK 546
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 156 DTSS-SHQRISIVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDL---VAEIKAGIAKGKKHAIVAITEHICDV--- 228
Cdd:TIGR02478 547 QSASaSKRRVFVVETMGGYSGYLATMAGLATGADAAYIPEEGISLKDLqedIEHLKETFAEGRAGKLILRNEKASKVytt 626
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 489958702 229 DELAKYIETETKR--ETRATVLGHIQRGGSPGPYDRILASRMGAYAIELLL 277
Cdd:TIGR02478 627 DFIARIISEEGKGrfDARTAVLGHMQQGGSPSPFDRVRATRLAIRAVDFIE 677
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
4-280 |
2.44e-46 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 166.92 E-value: 2.44e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 4 KIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVFGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEfrDEHIR 83
Cdd:cd00764 391 NIAIVNVGAPAAGMNAAVRSAVRYGLAHGHRPYAIYDGFEGLAKGQIVELGWIDVGGWTGRGGSELGTKRTLP--KKDLE 468
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 84 EVAiENMKKRGLDALVVIGGDGSYMGAKRL-------TEMGFPCIGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDRLRD 156
Cdd:cd00764 469 TIA-YNFQKYGIDGLIIVGGFEAYKGLLQLreareqyEEFCIPMVLIPATVSNNVPGTDFSLGSDTALNALMKYCDRIKQ 547
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 157 T-SSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVAEI-------KAGIAKGKKHAIVAITEHICDV 228
Cdd:cd00764 548 SaSGTKRRVFIVETMGGYCGYLATMTGLAVGADAAYVFEEPFNIRDLQENVehltekmKTTIGRGLVLRNEKCNENYTTV 627
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 489958702 229 DELAKYIETETKR-ETRATVLGHIQRGGSPGPYDRILASRMGAYAIELLLQGH 280
Cdd:cd00764 628 FTYELYSEEGKGVfDCRTNVLGHVQQGGAPSPFDRNFGTKFAVKAMKWIEQKL 680
|
|
| PTZ00286 |
PTZ00286 |
6-phospho-1-fructokinase; Provisional |
4-293 |
2.85e-38 |
|
6-phospho-1-fructokinase; Provisional
Pssm-ID: 185539 Cd Length: 459 Bit Score: 140.95 E-value: 2.85e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 4 KIGVLTSGGDAPGMNAAIRGVVRAALTE-GLE-VFGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDeh 81
Cdd:PTZ00286 89 KAGIVTCGGLCPGLNVVIRELVMNLINNyGVKtIYGAKYGYKGLYKEDWIKLDPKDVKTIHRLGGTILGSSRGGFDPK-- 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 82 ireVAIENMKKRGLDALVVIGGDGSYMGAKRLTE----MGFPC--IGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDRLR 155
Cdd:PTZ00286 167 ---VMVDTLIRHGINILFTLGGDGTHRGALAIYKelrrRKLNIsvVGIPKTIDNDIPIIDESFGFQTAVEEAQNAIRAAY 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 156 DTSSSHQR-ISIVEVMGRYCGDLTLAAAIAGGCEFVV-VPEVEFSREDLVAEIKAGIAKgKKHAIVAITEHIC------- 226
Cdd:PTZ00286 244 VEAKSAKNgVGIVKLMGRDSGFIALHASVASADVNVClIPEFDIPLEGVLEYIEQRLQK-KGHCVIVVAEGAGqslkdad 322
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 227 --------------DV-----DELAKYIEtetKRETRATVlGHIQ-----RGGSPGPYDRILASRMGAYAIELLLQGHGG 282
Cdd:PTZ00286 323 ldlgtdasgnkklwDIgvylkDEITKYLK---KKKPEHTV-KYIDpsymiRAVPANAADAKFCTQLAQNAVHGAMAGFTG 398
|
330
....*....|.
gi 489958702 283 RCVGIQNEKLV 293
Cdd:PTZ00286 399 FIIGHVHNNYV 409
|
|
| PRK14072 |
PRK14072 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; |
1-288 |
4.69e-27 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase;
Pssm-ID: 237600 [Multi-domain] Cd Length: 416 Bit Score: 109.56 E-value: 4.69e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 1 MIKKIGVLTSGGDAPGMNAAIRGVVRAAL--TEGLEVFGIYDGYLGLYEDRMVQLDRYSVSD---MINRGGTFLGSARFP 75
Cdd:PRK14072 2 MKGNALYAQSGGPTAVINASAAGVIEEARkhKKIGKVYGARNGIIGILDEDLIDLSKESDEAlaaLAHTPSGALGSCRYK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 76 EFRDEHIR---EVAIENMKKRGLDALVVIGGDGSYMGAKRLTE----MGFP--CIGLPGTIDNDIKGTDYTIGY-----F 141
Cdd:PRK14072 82 LKSLEEDRaeyERLLEVFKAHDIGYFFYNGGNDSMDTALKVSQlakkMGYPirCIGIPKTIDNDLPGTDHCPGFgsaakY 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 142 TAlGTVVEAIdrlRDTSSSHQ--RISIVEVMGRYCGDLTLAAAIA-----GGCEFVVVPEVEFSREDLVAEIKAGIAKGK 214
Cdd:PRK14072 162 IA-TSVLEAA---LDVAAMANtsKVFILEVMGRHAGWLAAAAALAkqnpdDAPHLIYLPERPFDEEKFLADVRAIVKRYG 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 215 KHAIVA-----------ITEHICDVDE------------LAKYIETETKRETRATVLGHIQRGGspgpydRILASR---- 267
Cdd:PRK14072 238 YCVVVVsegirdadgkfIAEAGLAEDAfghaqlggvapvLANLIKEKLGKKVHWAVLDYLQRAA------RHIASKtdve 311
|
330 340
....*....|....*....|....*
gi 489958702 268 ----MGAYAIELLLQGHGGRCVGIQ 288
Cdd:PRK14072 312 eayaVGKAAVEYALAGKNGVMPAIR 336
|
|
| PRK06830 |
PRK06830 |
ATP-dependent 6-phosphofructokinase; |
4-223 |
1.89e-25 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235869 Cd Length: 443 Bit Score: 105.34 E-value: 1.89e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 4 KIGVLTSGGDAPGMNAAIRGVVRAALTE-GL-EVFGIYDGYLGL---YEDRMVQLDRYSVSDMINRGGTFLGSARFPEFR 78
Cdd:PRK06830 82 KAAIVTCGGLCPGLNDVIRAIVLELHHHyGVrRILGIRYGYQGLiprYGHDPVELTPEVVADIHEFGGTILGSSRGPQDP 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 79 DEHIRevAIENMkkrGLDALVVIGGDGSYMGAKRLTE------MGFPCIGLPGTIDNDIKGTDYTIGYFTALGTVVEAID 152
Cdd:PRK06830 162 EEIVD--TLERM---NINILFVIGGDGTLRGASAIAEeierrgLKISVIGIPKTIDNDINFIQKSFGFETAVEKATEAIR 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 153 rlrdtsSSHQR-------ISIVEVMGRYCGDLTLAAAIAGG-CEFVVVPEVEFSRED---LVAEIKAGIAKgKKHAIVAI 221
Cdd:PRK06830 237 ------CAHVEangapngIGLVKLMGRHSGFIAAYAALASKdVNFVLIPEVPFDLEGpngLLAALEKRLAE-RGHAVIVV 309
|
..
gi 489958702 222 TE 223
Cdd:PRK06830 310 AE 311
|
|
| PLN02884 |
PLN02884 |
6-phosphofructokinase |
4-306 |
1.08e-24 |
|
6-phosphofructokinase
Pssm-ID: 178472 [Multi-domain] Cd Length: 411 Bit Score: 102.97 E-value: 1.08e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 4 KIGVLTSGGDAPGMNAAIRGVVRAALTEGLE-VFGIYDGYLGLYEDRM--VQLDRYSVSDMINRGGTFLGSARfpefRDE 80
Cdd:PLN02884 55 KAAIVTCGGLCPGLNDVIRQIVFTLEIYGVKnIVGIPFGYRGFFEKGLseMPLSRKVVQNIHLSGGSLLGVSR----GGA 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 81 HIREVaIENMKKRGLDALVVIGGDGSYMGAK------RLTEMGFPCIGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDRL 154
Cdd:PLN02884 131 KTSDI-VDSIEARGINMLFVLGGNGTHAGANaihnecRKRKMKVSVVGVPKTIDNDILLMDKTFGFDTAVEEAQRAINSA 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 155 R-DTSSSHQRISIVEVMGRYCGDLTLAAAIAGG-CEFVVVPEVEFS---REDLVAEIKAGIAKgKKHAIVAITEHiCDVD 229
Cdd:PLN02884 210 YiEAHSAYHGIGLVKLMGRSSGFIAMHASLASGqVDICLIPEVPFTldgPNGVLRHLEHLIET-KGSAVVCVAEG-AGQD 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 230 ELAK-----------------YIETETKRETRATVL---------GHIQRGGSPGPYDRILASRMGAYAIELLLQGHGGR 283
Cdd:PLN02884 288 LLQKtnatdasgnpvlgdigvHLQQEIKKHFKDIGVpadvkyidpTYMIRACRANASDAILCTVLGQNAVHGAFAGFSGI 367
|
330 340
....*....|....*....|...
gi 489958702 284 CVGIQNEKLVHHDIIDAIENMKR 306
Cdd:PLN02884 368 TVGICNTHYVYLPIPEVIAYPRR 390
|
|
| PLN02564 |
PLN02564 |
6-phosphofructokinase |
7-197 |
1.63e-24 |
|
6-phosphofructokinase
Pssm-ID: 178178 Cd Length: 484 Bit Score: 103.29 E-value: 1.63e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 7 VLTSGGDAPGMNAAIRGVVRaalteGL-------EVFGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSArfpefRD 79
Cdd:PLN02564 92 IVTCGGLCPGLNTVIREIVC-----GLsymygvtRILGIDGGYRGFYSRNTIPLTPKVVNDIHKRGGTILGTS-----RG 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 80 EHIREVAIENMKKRGLDALVVIGGDGSYMGAKRLTE----MGFPC--IGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDR 153
Cdd:PLN02564 162 GHDTSKIVDSIQDRGINQVYIIGGDGTQKGASVIYEeirrRGLKVavAGIPKTIDNDIPVIDKSFGFDTAVEEAQRAINA 241
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 489958702 154 LR-DTSSSHQRISIVEVMGRYCGDLTLAAAIAG-GCEFVVVPEVEF 197
Cdd:PLN02564 242 AHvEAESVENGIGLVKLMGRYSGFIAMYATLASrDVDCCLIPESPF 287
|
|
| PRK07085 |
PRK07085 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
3-236 |
1.50e-20 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 235930 Cd Length: 555 Bit Score: 91.91 E-value: 1.50e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 3 KKIGVLTSGGDAPGMNAAIRGVVRA--ALTEGLEVFGIYDGYLGLYEDRMVQLDRYSVSDMINRGG-TFLGSARFPEFRD 79
Cdd:PRK07085 71 LKVGVILSGGQAPGGHNVIAGLFDGlkKLNPDSKLFGFIGGPLGLLNGKYIEITEEVIDEYRNTGGfDMIGSGRTKIETE 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 80 EHIrEVAIENMKKRGLDALVVIGGDGSYMGAKRLTE------MGFPCIGLPGTIDNDIKGT--DYTIGYFTALGTVVEAI 151
Cdd:PRK07085 151 EQK-EACLETVKKLKLDGLVIIGGDDSNTNAAILAEyfakhgCKTQVIGVPKTIDGDLKNEfiETSFGFDTATKTYSEMI 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 152 DRL-RDTSSSHQRISIVEVMGRYcgdltlAAAIAGGCEFVVVP-------EVE---FSREDLVAEIKAGI----AKGKKH 216
Cdd:PRK07085 230 GNIsRDALSAKKYWHFIKLMGRS------ASHIALECALQTHPnicliseEVAekkMSLQDIVHYIASVIadraAKGKNY 303
|
250 260
....*....|....*....|....
gi 489958702 217 AIVAI----TEHICDVDELAKYIE 236
Cdd:PRK07085 304 GVILIpeglIEFIPEMKSLIKELN 327
|
|
| PTZ00287 |
PTZ00287 |
6-phosphofructokinase; Provisional |
2-223 |
2.34e-19 |
|
6-phosphofructokinase; Provisional
Pssm-ID: 240345 [Multi-domain] Cd Length: 1419 Bit Score: 88.94 E-value: 2.34e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 2 IKKIGVLTSGGDAPGMNAAIRGVVRAA--LTEGLEVFGIYDGYLGLYEDRMVQLDRYSVSDMINRGG-TFLGSARFPEFR 78
Cdd:PTZ00287 177 VLKIGIILSGGPAPGGHNVISGIYDYAkrYNEQSQVIGFLGGIDGLYSKNYVTITDSLMNRFRNLGGfNMLWSGRGKVRN 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 79 DEHIreVAIENM-KKRGLDALVVIGGDGSYMGAKRLTE------MGFPCIGLPGTIDNDIK--GTDYTIGYFTALGTVVE 149
Cdd:PTZ00287 257 KDDL--IAIENIvAKLKLNGLVIIGGDGSNSNAALISEyfaerqIPISIIGIPKTIDGDLKseAIEISFGFDTATKTYSE 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 150 AIDRL-RDTSSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFVVV-PEVE---FSREDLVAEIKAGIAK----GKKHAIVA 220
Cdd:PTZ00287 335 VIGNLcTDVKTGHNVYHVVRVMGRSASHVVLECALQTRPNIVLIgEEVEkenLSLKDIVSNIVNTILKrrslNKNYGVIL 414
|
...
gi 489958702 221 ITE 223
Cdd:PTZ00287 415 IPE 417
|
|
| PTZ00468 |
PTZ00468 |
phosphofructokinase family protein; Provisional |
3-223 |
5.21e-17 |
|
phosphofructokinase family protein; Provisional
Pssm-ID: 185647 [Multi-domain] Cd Length: 1328 Bit Score: 81.94 E-value: 5.21e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 3 KKIGVLTSGGDAPGMNAAIRGVVR--AALTEGLEVFGIYDGYLGLYEDRMVQLDRYSVSDMINRGG-TFLGSARFPEFRD 79
Cdd:PTZ00468 103 RRIGVVLSGGQASGGHNVIAGLMSyiKLCNQSSQLFGFLGGPEGVYSERYRELTEDDINGILNQGGfNIICSGRHKIETE 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 80 EHIReVAIENMKKRGLDALVVIGGDGSYMGAKRLTEM------GFPCIGLPGTIDNDIKG--TDYTIGYFTALGTVVEAI 151
Cdd:PTZ00468 183 EQMR-ASLEICEKLKLHGLVVIGGDDSNTNAAVLAEYfkrnssSTVVVGCPKTIDGDLKNevIETSFGYDTAVKTYSEQI 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 152 DRLRDT-SSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFVVVPEvEFSRED-----LVAEIKAGIAK----GKKHAIVAI 221
Cdd:PTZ00468 262 GSIMDAiKTEGYGYYFVRLMGRSASHITLECGLQTRANMILIGE-EIKEENrslmsIVDEIVEMILKrdslGKKHGIVLL 340
|
..
gi 489958702 222 TE 223
Cdd:PTZ00468 341 PE 342
|
|
| Pyrophosphate_PFK |
cd00765 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
4-228 |
3.89e-16 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include pyrophosphate-dependent phosphofructokinases. These are found in bacteria as well as plants. These may be dimeric nonallosteric enzymes as in bacteria or allosteric heterotetramers as in plants.
Pssm-ID: 238390 Cd Length: 550 Bit Score: 78.76 E-value: 3.89e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 4 KIGVLTSGGDAPGMNAAIRGVVRA--ALTEGLEVFGIYDGYLGLYEDRMVQLDRYSVSDMINRGG-TFLGSARFPEFRDE 80
Cdd:cd00765 74 KIGIVLSGGQAPGGHNVISGLFDYlkERAKGSTLYGFKGGPAGILKCDYIELNAEYIQPYRNTGGfDMICSGRTKIETED 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 81 HIREvAIENMKKRGLDALVVIGGDGSYMGAKRLTE------MGFPCIGLPGTIDNDIKG--TDYTIGYFTALGTVVEAID 152
Cdd:cd00765 154 QFKQ-AEETAKKLDLDALVVIGGDDSNTNAALLAEnfrskgLKTRVIGVPKTIDGDLKNkeIETSFGFDTATKIYSELIG 232
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489958702 153 RL-RDTSSSHQRISIVEVMGRYcgdltlAAAIAGGCEFVVVPEVEFSREDLVAeikagiakgKKHAIVAITEHICDV 228
Cdd:cd00765 233 NVmRDARSTGKYWHFVKLMGRS------ASHIALECALKTHPNICIISEEVSA---------QKQTLKNITDYMVDV 294
|
|
| PRK06555 |
PRK06555 |
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated |
1-207 |
1.16e-14 |
|
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated
Pssm-ID: 180620 [Multi-domain] Cd Length: 403 Bit Score: 73.89 E-value: 1.16e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 1 MIKKIGVLTSGGDAPGMNAAIRGVVRA--ALTEGLEVFGIYDGYLGLYEDRMVQLD---RYSVSDMINRGGTFLGSAR-- 73
Cdd:PRK06555 2 AVKKVALLTAGGLAPCLSSAVGGLIERytEIAPEVEIIAYRSGYQGLLLGDSIEITpavRANAGLLHRYGGSPIGNSRvk 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 74 FPEFRD----------EHIREVAIENMKKRGLDALVVIGGD---------GSYMGAK--RLTemgfpCIGLPGTIDNDIK 132
Cdd:PRK06555 82 LTNVADcvkrglvkegENPLKVAAERLAADGVDILHTIGGDdtnttaadlAAYLAENgyDLT-----VVGLPKTIDNDVV 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 133 GTDYTIGYFTALGTVVEAIDRLRDTSSSHQRISIV-EVMGRYCGDLTLAAAIA-----GGCEF---------------VV 191
Cdd:PRK06555 157 PIRQSLGAWTAAEQGARFFDNVINEHSANPRMLIIhEVMGRNCGWLTAATARAyrewlDRQEYvpgfglsaerwdihaVY 236
|
250
....*....|....*.
gi 489958702 192 VPEVEFsreDLVAEIK 207
Cdd:PRK06555 237 LPEMAF---DLEAEAE 249
|
|
| PLN02251 |
PLN02251 |
pyrophosphate-dependent phosphofructokinase |
4-183 |
5.30e-12 |
|
pyrophosphate-dependent phosphofructokinase
Pssm-ID: 215140 Cd Length: 568 Bit Score: 66.35 E-value: 5.30e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 4 KIGVLTSGGDAPGMNAAIRGVVR--AALTEGLEVFGIYDGYLGLYEDRMVQLDRYSVSDMINRGG-TFLGSARFPEFRDE 80
Cdd:PLN02251 98 KIGVVLSGGQAPGGHNVISGIFDylQEHAKGSVLYGFKGGPAGIMKCKYVELTAEFIYPYRNQGGfDMICSGRDKIETPE 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 81 HIREvAIENMKKRGLDALVVIGGDGSYMGAKRLTE------MGFPCIGLPGTIDNDIKGTDYTI--GYFTALGTVVEAI- 151
Cdd:PLN02251 178 QFKQ-AEETATKLDLDGLVVIGGDDSNTNACLLAEyfraknLKTRVIGCPKTIDGDLKSKEVPTsfGFDTACKIYSEMIg 256
|
170 180 190
....*....|....*....|....*....|..
gi 489958702 152 DRLRDTSSSHQRISIVEVMGRYCGDLTLAAAI 183
Cdd:PLN02251 257 NVMIDARSTGKYYHFVRLMGRAASHITLECAL 288
|
|
| PLN03028 |
PLN03028 |
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
4-223 |
5.37e-06 |
|
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 215543 Cd Length: 610 Bit Score: 47.85 E-value: 5.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 4 KIGVLTSGGDAPGMNAAIRGVVRA--ALTEGLEVFGIYDGYLGLYEDRMVQLDRYSVSDMINRGG-TFLGSARfpefrdE 80
Cdd:PLN03028 81 RVGVVFCGRQSPGGHNVIWGLHDAlkAHNPNSVLLGFLGGTEGLFAQKTLEITDDVLSTYKNQGGyDLLGRTK------D 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 81 HIREV--------AIENMKkrgLDALVVIGGDGSYMGAKRLTE--MGFPC----IGLPGTIDNDIKG--TDYTIGYFTAL 144
Cdd:PLN03028 155 QIRTTeqvnaalaACEALK---LDGLVIIGGVTSNTDAAQLAEtfAEAKCktkvVGVPVTLNGDLKNqfVETNVGFDTIC 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489958702 145 GTVVEAIDRL-RDTSSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFVVV-PEVEFSR---EDLVAEI----KAGIAKGKK 215
Cdd:PLN03028 232 KVNSQLISNVcTDALSAEKYYYFIRLMGRKASHVALECALQSHPNMVILgEEVAASKltlFDITKQIcdavQARAEQDKN 311
|
....*...
gi 489958702 216 HAIVAITE 223
Cdd:PLN03028 312 HGVILIPE 319
|
|
| |
